Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : COT1_MOUSE

For an explanation of this page, click here

COT1_MOUSE
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COT1_HUMAN
θ value	0 (rank : 1)	NC score	0.999389 (rank : 2)
Query Neighborhood Hits	160	Target Neighborhood Hits	159	Shared Neighborhood Hits	147
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	160	Target Neighborhood Hits	160	Shared Neighborhood Hits	160
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT2_HUMAN
θ value	0 (rank : 3)	NC score	0.998128 (rank : 3)
Query Neighborhood Hits	160	Target Neighborhood Hits	135	Shared Neighborhood Hits	114
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	0 (rank : 4)	NC score	0.998128 (rank : 4)
Query Neighborhood Hits	160	Target Neighborhood Hits	135	Shared Neighborhood Hits	114
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

EAR2_HUMAN
θ value	2.87295e-139 (rank : 5)	NC score	0.995521 (rank : 5)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
θ value	7.07634e-138 (rank : 6)	NC score	0.995434 (rank : 6)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRA_HUMAN
θ value	1.45253e-74 (rank : 7)	NC score	0.975961 (rank : 14)
Query Neighborhood Hits	160	Target Neighborhood Hits	223	Shared Neighborhood Hits	100
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
θ value	1.45253e-74 (rank : 8)	NC score	0.978885 (rank : 13)
Query Neighborhood Hits	160	Target Neighborhood Hits	129	Shared Neighborhood Hits	99
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_HUMAN
θ value	5.51964e-74 (rank : 9)	NC score	0.979875 (rank : 11)
Query Neighborhood Hits	160	Target Neighborhood Hits	114	Shared Neighborhood Hits	101
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
θ value	1.04096e-72 (rank : 10)	NC score	0.979652 (rank : 12)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	99
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

NR2E3_HUMAN
θ value	3.95564e-72 (rank : 11)	NC score	0.984481 (rank : 7)
Query Neighborhood Hits	160	Target Neighborhood Hits	102	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
θ value	1.66191e-70 (rank : 12)	NC score	0.983777 (rank : 8)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RXRB_HUMAN
θ value	2.3998e-69 (rank : 13)	NC score	0.971308 (rank : 20)
Query Neighborhood Hits	160	Target Neighborhood Hits	280	Shared Neighborhood Hits	113
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	5.34618e-69 (rank : 14)	NC score	0.974917 (rank : 16)
Query Neighborhood Hits	160	Target Neighborhood Hits	230	Shared Neighborhood Hits	103
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

NR2E1_HUMAN
θ value	1.19101e-68 (rank : 15)	NC score	0.982744 (rank : 9)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E1_MOUSE
θ value	1.5555e-68 (rank : 16)	NC score	0.982668 (rank : 10)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

HNF4A_MOUSE
θ value	2.48917e-58 (rank : 17)	NC score	0.974763 (rank : 18)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
θ value	4.69435e-57 (rank : 18)	NC score	0.974271 (rank : 19)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_MOUSE
θ value	1.78386e-56 (rank : 19)	NC score	0.974804 (rank : 17)
Query Neighborhood Hits	160	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_HUMAN
θ value	3.0428e-56 (rank : 20)	NC score	0.974974 (rank : 15)
Query Neighborhood Hits	160	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

ERR2_MOUSE
θ value	1.04822e-48 (rank : 21)	NC score	0.955353 (rank : 21)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR2_HUMAN
θ value	1.36902e-48 (rank : 22)	NC score	0.952977 (rank : 24)
Query Neighborhood Hits	160	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR3_HUMAN
θ value	6.7944e-48 (rank : 23)	NC score	0.955132 (rank : 22)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	6.7944e-48 (rank : 24)	NC score	0.955132 (rank : 23)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR1_HUMAN
θ value	1.56636e-44 (rank : 25)	NC score	0.952375 (rank : 25)
Query Neighborhood Hits	160	Target Neighborhood Hits	157	Shared Neighborhood Hits	100
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

NR4A2_HUMAN
θ value	5.57106e-42 (rank : 26)	NC score	0.938994 (rank : 27)
Query Neighborhood Hits	160	Target Neighborhood Hits	120	Shared Neighborhood Hits	98
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	7.27602e-42 (rank : 27)	NC score	0.939035 (rank : 26)
Query Neighborhood Hits	160	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A1_HUMAN
θ value	1.79215e-40 (rank : 28)	NC score	0.938676 (rank : 28)
Query Neighborhood Hits	160	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

RARG1_HUMAN
θ value	2.34062e-40 (rank : 29)	NC score	0.933020 (rank : 37)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
θ value	2.34062e-40 (rank : 30)	NC score	0.933165 (rank : 35)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

NR4A1_MOUSE
θ value	3.99248e-40 (rank : 31)	NC score	0.937378 (rank : 29)
Query Neighborhood Hits	160	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

RARB_MOUSE
θ value	1.98146e-39 (rank : 32)	NC score	0.932591 (rank : 40)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARG1_MOUSE
θ value	1.98146e-39 (rank : 33)	NC score	0.932336 (rank : 41)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	1.98146e-39 (rank : 34)	NC score	0.932626 (rank : 39)
Query Neighborhood Hits	160	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARA_HUMAN
θ value	4.41421e-39 (rank : 35)	NC score	0.933179 (rank : 34)
Query Neighborhood Hits	160	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	7.52953e-39 (rank : 36)	NC score	0.933084 (rank : 36)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_HUMAN
θ value	7.52953e-39 (rank : 37)	NC score	0.932631 (rank : 38)
Query Neighborhood Hits	160	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

NR4A3_MOUSE
θ value	2.86122e-38 (rank : 38)	NC score	0.936514 (rank : 30)
Query Neighborhood Hits	160	Target Neighborhood Hits	127	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
θ value	5.96599e-36 (rank : 39)	NC score	0.935238 (rank : 31)
Query Neighborhood Hits	160	Target Neighborhood Hits	131	Shared Neighborhood Hits	94
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

TR4_HUMAN
θ value	1.01765e-35 (rank : 40)	NC score	0.933955 (rank : 32)
Query Neighborhood Hits	160	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
θ value	1.32909e-35 (rank : 41)	NC score	0.933597 (rank : 33)
Query Neighborhood Hits	160	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

ESR1_HUMAN
θ value	8.06329e-33 (rank : 42)	NC score	0.928482 (rank : 47)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_MOUSE
θ value	2.34606e-32 (rank : 43)	NC score	0.928561 (rank : 46)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR1H3_HUMAN
θ value	5.22648e-32 (rank : 44)	NC score	0.923489 (rank : 50)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_MOUSE
θ value	1.16434e-31 (rank : 45)	NC score	0.922248 (rank : 51)
Query Neighborhood Hits	160	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

TR2_MOUSE
θ value	1.16434e-31 (rank : 46)	NC score	0.930973 (rank : 43)
Query Neighborhood Hits	160	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

PPARD_MOUSE
θ value	5.77852e-31 (rank : 47)	NC score	0.913146 (rank : 63)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

PPARA_HUMAN
θ value	9.8567e-31 (rank : 48)	NC score	0.915841 (rank : 58)
Query Neighborhood Hits	160	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARD_HUMAN
θ value	1.28732e-30 (rank : 49)	NC score	0.914488 (rank : 61)
Query Neighborhood Hits	160	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

ESR2_MOUSE
θ value	1.6813e-30 (rank : 50)	NC score	0.930822 (rank : 44)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

PPARG_MOUSE
θ value	2.19584e-30 (rank : 51)	NC score	0.911535 (rank : 67)
Query Neighborhood Hits	160	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_HUMAN
θ value	2.86786e-30 (rank : 52)	NC score	0.911906 (rank : 65)
Query Neighborhood Hits	160	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

ESR2_HUMAN
θ value	3.74554e-30 (rank : 53)	NC score	0.932195 (rank : 42)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

PPARA_MOUSE
θ value	4.89182e-30 (rank : 54)	NC score	0.914873 (rank : 60)
Query Neighborhood Hits	160	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

NR1H2_MOUSE
θ value	1.08979e-29 (rank : 55)	NC score	0.913820 (rank : 62)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR1H4_MOUSE
θ value	5.40856e-29 (rank : 56)	NC score	0.920658 (rank : 55)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

TR2_HUMAN
θ value	1.57365e-28 (rank : 57)	NC score	0.928689 (rank : 45)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR5A2_MOUSE
θ value	3.50572e-28 (rank : 58)	NC score	0.921678 (rank : 53)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR1H4_HUMAN
θ value	7.80994e-28 (rank : 59)	NC score	0.921368 (rank : 54)
Query Neighborhood Hits	160	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

THA_HUMAN
θ value	1.33217e-27 (rank : 60)	NC score	0.909449 (rank : 68)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
θ value	1.33217e-27 (rank : 61)	NC score	0.909443 (rank : 69)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

NR1I3_HUMAN
θ value	1.12775e-26 (rank : 62)	NC score	0.922187 (rank : 52)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR5A2_HUMAN
θ value	4.28545e-26 (rank : 63)	NC score	0.918438 (rank : 56)
Query Neighborhood Hits	160	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

RORG_HUMAN
θ value	1.24688e-25 (rank : 64)	NC score	0.898792 (rank : 80)
Query Neighborhood Hits	160	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

RORG_MOUSE
θ value	2.12685e-25 (rank : 65)	NC score	0.902022 (rank : 75)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORA_HUMAN
θ value	3.62785e-25 (rank : 66)	NC score	0.897906 (rank : 81)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	3.62785e-25 (rank : 67)	NC score	0.897877 (rank : 82)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORB_HUMAN
θ value	4.73814e-25 (rank : 68)	NC score	0.899256 (rank : 78)
Query Neighborhood Hits	160	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	4.73814e-25 (rank : 69)	NC score	0.899028 (rank : 79)
Query Neighborhood Hits	160	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

THB1_HUMAN
θ value	8.08199e-25 (rank : 70)	NC score	0.903274 (rank : 73)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_HUMAN
θ value	8.08199e-25 (rank : 71)	NC score	0.903702 (rank : 72)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

NR1I3_MOUSE
θ value	1.05554e-24 (rank : 72)	NC score	0.917588 (rank : 57)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

THB1_MOUSE
θ value	5.23862e-24 (rank : 73)	NC score	0.901910 (rank : 76)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	5.23862e-24 (rank : 74)	NC score	0.901774 (rank : 77)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

ANDR_HUMAN
θ value	3.39556e-23 (rank : 75)	NC score	0.876678 (rank : 89)
Query Neighborhood Hits	160	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_HUMAN
θ value	3.39556e-23 (rank : 76)	NC score	0.880433 (rank : 87)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
θ value	4.43474e-23 (rank : 77)	NC score	0.871854 (rank : 91)
Query Neighborhood Hits	160	Target Neighborhood Hits	149	Shared Neighborhood Hits	94
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

ANDR_MOUSE
θ value	7.56453e-23 (rank : 78)	NC score	0.877868 (rank : 88)
Query Neighborhood Hits	160	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

NR1D2_MOUSE
θ value	3.75424e-22 (rank : 79)	NC score	0.902566 (rank : 74)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

NR6A1_MOUSE
θ value	3.75424e-22 (rank : 80)	NC score	0.925559 (rank : 49)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

MCR_MOUSE
θ value	8.36355e-22 (rank : 81)	NC score	0.868120 (rank : 93)
Query Neighborhood Hits	160	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

NR1D2_HUMAN
θ value	1.09232e-21 (rank : 82)	NC score	0.904800 (rank : 71)
Query Neighborhood Hits	160	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D1_HUMAN
θ value	1.42661e-21 (rank : 83)	NC score	0.911609 (rank : 66)
Query Neighborhood Hits	160	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

STF1_HUMAN
θ value	1.42661e-21 (rank : 84)	NC score	0.912876 (rank : 64)
Query Neighborhood Hits	160	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	1.42661e-21 (rank : 85)	NC score	0.915578 (rank : 59)
Query Neighborhood Hits	160	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR1H2_HUMAN
θ value	1.86321e-21 (rank : 86)	NC score	0.905507 (rank : 70)
Query Neighborhood Hits	160	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

NR6A1_HUMAN
θ value	1.86321e-21 (rank : 87)	NC score	0.926638 (rank : 48)
Query Neighborhood Hits	160	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

PRGR_HUMAN
θ value	1.86321e-21 (rank : 88)	NC score	0.869424 (rank : 92)
Query Neighborhood Hits	160	Target Neighborhood Hits	163	Shared Neighborhood Hits	96
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
θ value	3.17815e-21 (rank : 89)	NC score	0.864218 (rank : 94)
Query Neighborhood Hits	160	Target Neighborhood Hits	286	Shared Neighborhood Hits	105
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
θ value	2.69047e-20 (rank : 90)	NC score	0.646185 (rank : 95)
Query Neighborhood Hits	160	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

GCR_MOUSE
θ value	4.58923e-20 (rank : 91)	NC score	0.873392 (rank : 90)
Query Neighborhood Hits	160	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

SHP_MOUSE
θ value	2.5182e-18 (rank : 92)	NC score	0.639195 (rank : 96)
Query Neighborhood Hits	160	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

VDR_HUMAN
θ value	2.13179e-17 (rank : 93)	NC score	0.895799 (rank : 84)
Query Neighborhood Hits	160	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
θ value	2.13179e-17 (rank : 94)	NC score	0.897309 (rank : 83)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PXR_HUMAN
θ value	1.38178e-16 (rank : 95)	NC score	0.892596 (rank : 86)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

PXR_MOUSE
θ value	3.07829e-16 (rank : 96)	NC score	0.894664 (rank : 85)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

DAX1_HUMAN
θ value	6.41864e-14 (rank : 97)	NC score	0.592779 (rank : 98)
Query Neighborhood Hits	160	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

DAX1_MOUSE
θ value	6.00763e-12 (rank : 98)	NC score	0.610337 (rank : 97)
Query Neighborhood Hits	160	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

CO4A2_HUMAN
θ value	0.00509761 (rank : 99)	NC score	0.045550 (rank : 101)
Query Neighborhood Hits	160	Target Neighborhood Hits	454	Shared Neighborhood Hits	47
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO5A2_HUMAN
θ value	0.00665767 (rank : 100)	NC score	0.045797 (rank : 100)
Query Neighborhood Hits	160	Target Neighborhood Hits	760	Shared Neighborhood Hits	50
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO4A1_HUMAN
θ value	0.0252991 (rank : 101)	NC score	0.044376 (rank : 105)
Query Neighborhood Hits	160	Target Neighborhood Hits	425	Shared Neighborhood Hits	49
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO7A1_HUMAN
θ value	0.0563607 (rank : 102)	NC score	0.029203 (rank : 129)
Query Neighborhood Hits	160	Target Neighborhood Hits	807	Shared Neighborhood Hits	49
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO9A1_MOUSE
θ value	0.0961366 (rank : 103)	NC score	0.045117 (rank : 103)
Query Neighborhood Hits	160	Target Neighborhood Hits	477	Shared Neighborhood Hits	50
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

C1QC_MOUSE
θ value	0.125558 (rank : 104)	NC score	0.035642 (rank : 121)
Query Neighborhood Hits	160	Target Neighborhood Hits	150	Shared Neighborhood Hits	38
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

CO4A3_HUMAN
θ value	0.163984 (rank : 105)	NC score	0.040676 (rank : 111)
Query Neighborhood Hits	160	Target Neighborhood Hits	421	Shared Neighborhood Hits	45
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A5_HUMAN
θ value	0.163984 (rank : 106)	NC score	0.052274 (rank : 99)
Query Neighborhood Hits	160	Target Neighborhood Hits	383	Shared Neighborhood Hits	51
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO1A2_HUMAN
θ value	0.21417 (rank : 107)	NC score	0.044432 (rank : 104)
Query Neighborhood Hits	160	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A1_MOUSE
θ value	0.21417 (rank : 108)	NC score	0.040536 (rank : 112)
Query Neighborhood Hits	160	Target Neighborhood Hits	450	Shared Neighborhood Hits	48
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A1_HUMAN
θ value	0.365318 (rank : 109)	NC score	0.039016 (rank : 113)
Query Neighborhood Hits	160	Target Neighborhood Hits	420	Shared Neighborhood Hits	47
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A2_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.045328 (rank : 102)
Query Neighborhood Hits	160	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO2A1_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.043200 (rank : 106)
Query Neighborhood Hits	160	Target Neighborhood Hits	486	Shared Neighborhood Hits	51
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	0.813845 (rank : 112)	NC score	0.042605 (rank : 108)
Query Neighborhood Hits	160	Target Neighborhood Hits	483	Shared Neighborhood Hits	49
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A4_HUMAN
θ value	0.813845 (rank : 113)	NC score	0.042249 (rank : 109)
Query Neighborhood Hits	160	Target Neighborhood Hits	440	Shared Neighborhood Hits	50
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CEL_HUMAN
θ value	1.06291 (rank : 114)	NC score	0.015545 (rank : 135)
Query Neighborhood Hits	160	Target Neighborhood Hits	896	Shared Neighborhood Hits	42
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ULK1_HUMAN
θ value	1.06291 (rank : 115)	NC score	-0.007345 (rank : 158)
Query Neighborhood Hits	160	Target Neighborhood Hits	1121	Shared Neighborhood Hits	26
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CO6A1_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.033083 (rank : 126)
Query Neighborhood Hits	160	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ZN335_HUMAN
θ value	1.38821 (rank : 117)	NC score	-0.006372 (rank : 157)
Query Neighborhood Hits	160	Target Neighborhood Hits	973	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

CO4A2_MOUSE
θ value	1.81305 (rank : 118)	NC score	0.042718 (rank : 107)
Query Neighborhood Hits	160	Target Neighborhood Hits	492	Shared Neighborhood Hits	52
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

BOC_HUMAN
θ value	2.36792 (rank : 119)	NC score	-0.000786 (rank : 154)
Query Neighborhood Hits	160	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CO1A2_MOUSE
θ value	2.36792 (rank : 120)	NC score	0.038333 (rank : 115)
Query Neighborhood Hits	160	Target Neighborhood Hits	388	Shared Neighborhood Hits	46
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO5A3_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.041657 (rank : 110)
Query Neighborhood Hits	160	Target Neighborhood Hits	433	Shared Neighborhood Hits	49
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

INVS_MOUSE
θ value	2.36792 (rank : 122)	NC score	-0.002787 (rank : 155)
Query Neighborhood Hits	160	Target Neighborhood Hits	609	Shared Neighborhood Hits	5
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

OXRP_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.006677 (rank : 142)
Query Neighborhood Hits	160	Target Neighborhood Hits	544	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

COBA2_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.033535 (rank : 125)
Query Neighborhood Hits	160	Target Neighborhood Hits	501	Shared Neighborhood Hits	48
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CXCC1_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.006553 (rank : 143)
Query Neighborhood Hits	160	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

PARD3_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.004576 (rank : 146)
Query Neighborhood Hits	160	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

RTEL1_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.005490 (rank : 144)
Query Neighborhood Hits	160	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

CO1A1_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.038097 (rank : 116)
Query Neighborhood Hits	160	Target Neighborhood Hits	475	Shared Neighborhood Hits	50
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A2_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.037163 (rank : 119)
Query Neighborhood Hits	160	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COAA1_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.034564 (rank : 123)
Query Neighborhood Hits	160	Target Neighborhood Hits	286	Shared Neighborhood Hits	44
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COEA1_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.022107 (rank : 133)
Query Neighborhood Hits	160	Target Neighborhood Hits	427	Shared Neighborhood Hits	45
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CONA1_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.034671 (rank : 122)
Query Neighborhood Hits	160	Target Neighborhood Hits	281	Shared Neighborhood Hits	43
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CONA1_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.037743 (rank : 118)
Query Neighborhood Hits	160	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

KCNH6_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.001753 (rank : 150)
Query Neighborhood Hits	160	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

PEX6_MOUSE
θ value	4.03905 (rank : 135)	NC score	0.002046 (rank : 149)
Query Neighborhood Hits	160	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PODO_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.007063 (rank : 141)
Query Neighborhood Hits	160	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

ZN385_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.019901 (rank : 134)
Query Neighborhood Hits	160	Target Neighborhood Hits	614	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CO4A6_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.038984 (rank : 114)
Query Neighborhood Hits	160	Target Neighborhood Hits	318	Shared Neighborhood Hits	45
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

SI1L1_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.004868 (rank : 145)
Query Neighborhood Hits	160	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

ZN341_HUMAN
θ value	5.27518 (rank : 140)	NC score	-0.005559 (rank : 156)
Query Neighborhood Hits	160	Target Neighborhood Hits	803	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

BCL9_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.032413 (rank : 128)
Query Neighborhood Hits	160	Target Neighborhood Hits	770	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

C1QT5_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.029093 (rank : 130)
Query Neighborhood Hits	160	Target Neighborhood Hits	131	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

CO6A1_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.032565 (rank : 127)
Query Neighborhood Hits	160	Target Neighborhood Hits	241	Shared Neighborhood Hits	39
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

COBA1_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.035815 (rank : 120)
Query Neighborhood Hits	160	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.033610 (rank : 124)
Query Neighborhood Hits	160	Target Neighborhood Hits	487	Shared Neighborhood Hits	47
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

ERB1_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.008220 (rank : 140)
Query Neighborhood Hits	160	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

PCNT_HUMAN
θ value	6.88961 (rank : 147)	NC score	-0.008597 (rank : 160)
Query Neighborhood Hits	160	Target Neighborhood Hits	1551	Shared Neighborhood Hits	6
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RMD5B_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.009709 (rank : 138)
Query Neighborhood Hits	160	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YQ7	Gene names	Rmnd5b
Domain Architecture
Description	RMD5 homolog B.

ADIPO_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.023424 (rank : 131)
Query Neighborhood Hits	160	Target Neighborhood Hits	169	Shared Neighborhood Hits	37
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

ADIPO_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.023168 (rank : 132)
Query Neighborhood Hits	160	Target Neighborhood Hits	182	Shared Neighborhood Hits	37
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

CIC_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.000600 (rank : 152)
Query Neighborhood Hits	160	Target Neighborhood Hits	992	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO9A3_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.037892 (rank : 117)
Query Neighborhood Hits	160	Target Neighborhood Hits	361	Shared Neighborhood Hits	46
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CXCC1_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.004285 (rank : 147)
Query Neighborhood Hits	160	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

FA62A_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.000996 (rank : 151)
Query Neighborhood Hits	160	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FCN1_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.013301 (rank : 136)
Query Neighborhood Hits	160	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

LAMC2_HUMAN
θ value	8.99809 (rank : 156)	NC score	-0.000563 (rank : 153)
Query Neighborhood Hits	160	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

PKHA6_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.010330 (rank : 137)
Query Neighborhood Hits	160	Target Neighborhood Hits	556	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKN3_MOUSE
θ value	8.99809 (rank : 158)	NC score	-0.008416 (rank : 159)
Query Neighborhood Hits	160	Target Neighborhood Hits	1009	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

RMD5B_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.008723 (rank : 139)
Query Neighborhood Hits	160	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q96G75, Q6UVY7, Q9H6F6	Gene names	RMND5B
Domain Architecture
Description	RMD5 homolog B.

ZDHC8_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.004153 (rank : 148)
Query Neighborhood Hits	160	Target Neighborhood Hits	243	Shared Neighborhood Hits	29
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

Hits sorted by NC score

COT1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	160	Target Neighborhood Hits	160	Shared Neighborhood Hits	160
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.999389 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	160	Target Neighborhood Hits	159	Shared Neighborhood Hits	147
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT2_HUMAN
NC score	0.998128 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	160	Target Neighborhood Hits	135	Shared Neighborhood Hits	114
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.998128 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	160	Target Neighborhood Hits	135	Shared Neighborhood Hits	114
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

EAR2_HUMAN
NC score	0.995521 (rank : 5)	θ value	2.87295e-139 (rank : 5)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
NC score	0.995434 (rank : 6)	θ value	7.07634e-138 (rank : 6)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

NR2E3_HUMAN
NC score	0.984481 (rank : 7)	θ value	3.95564e-72 (rank : 11)
Query Neighborhood Hits	160	Target Neighborhood Hits	102	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
NC score	0.983777 (rank : 8)	θ value	1.66191e-70 (rank : 12)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_HUMAN
NC score	0.982744 (rank : 9)	θ value	1.19101e-68 (rank : 15)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E1_MOUSE
NC score	0.982668 (rank : 10)	θ value	1.5555e-68 (rank : 16)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

RXRG_HUMAN
NC score	0.979875 (rank : 11)	θ value	5.51964e-74 (rank : 9)
Query Neighborhood Hits	160	Target Neighborhood Hits	114	Shared Neighborhood Hits	101
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
NC score	0.979652 (rank : 12)	θ value	1.04096e-72 (rank : 10)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	99
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_MOUSE
NC score	0.978885 (rank : 13)	θ value	1.45253e-74 (rank : 8)
Query Neighborhood Hits	160	Target Neighborhood Hits	129	Shared Neighborhood Hits	99
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_HUMAN
NC score	0.975961 (rank : 14)	θ value	1.45253e-74 (rank : 7)
Query Neighborhood Hits	160	Target Neighborhood Hits	223	Shared Neighborhood Hits	100
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

HNF4G_HUMAN
NC score	0.974974 (rank : 15)	θ value	3.0428e-56 (rank : 20)
Query Neighborhood Hits	160	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

RXRB_MOUSE
NC score	0.974917 (rank : 16)	θ value	5.34618e-69 (rank : 14)
Query Neighborhood Hits	160	Target Neighborhood Hits	230	Shared Neighborhood Hits	103
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

HNF4G_MOUSE
NC score	0.974804 (rank : 17)	θ value	1.78386e-56 (rank : 19)
Query Neighborhood Hits	160	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_MOUSE
NC score	0.974763 (rank : 18)	θ value	2.48917e-58 (rank : 17)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
NC score	0.974271 (rank : 19)	θ value	4.69435e-57 (rank : 18)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

RXRB_HUMAN
NC score	0.971308 (rank : 20)	θ value	2.3998e-69 (rank : 13)
Query Neighborhood Hits	160	Target Neighborhood Hits	280	Shared Neighborhood Hits	113
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

ERR2_MOUSE
NC score	0.955353 (rank : 21)	θ value	1.04822e-48 (rank : 21)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
NC score	0.955132 (rank : 22)	θ value	6.7944e-48 (rank : 23)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.955132 (rank : 23)	θ value	6.7944e-48 (rank : 24)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_HUMAN
NC score	0.952977 (rank : 24)	θ value	1.36902e-48 (rank : 22)
Query Neighborhood Hits	160	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR1_HUMAN
NC score	0.952375 (rank : 25)	θ value	1.56636e-44 (rank : 25)
Query Neighborhood Hits	160	Target Neighborhood Hits	157	Shared Neighborhood Hits	100
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

NR4A2_MOUSE
NC score	0.939035 (rank : 26)	θ value	7.27602e-42 (rank : 27)
Query Neighborhood Hits	160	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A2_HUMAN
NC score	0.938994 (rank : 27)	θ value	5.57106e-42 (rank : 26)
Query Neighborhood Hits	160	Target Neighborhood Hits	120	Shared Neighborhood Hits	98
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A1_HUMAN
NC score	0.938676 (rank : 28)	θ value	1.79215e-40 (rank : 28)
Query Neighborhood Hits	160	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A1_MOUSE
NC score	0.937378 (rank : 29)	θ value	3.99248e-40 (rank : 31)
Query Neighborhood Hits	160	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

NR4A3_MOUSE
NC score	0.936514 (rank : 30)	θ value	2.86122e-38 (rank : 38)
Query Neighborhood Hits	160	Target Neighborhood Hits	127	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
NC score	0.935238 (rank : 31)	θ value	5.96599e-36 (rank : 39)
Query Neighborhood Hits	160	Target Neighborhood Hits	131	Shared Neighborhood Hits	94
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

TR4_HUMAN
NC score	0.933955 (rank : 32)	θ value	1.01765e-35 (rank : 40)
Query Neighborhood Hits	160	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.933597 (rank : 33)	θ value	1.32909e-35 (rank : 41)
Query Neighborhood Hits	160	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RARA_HUMAN
NC score	0.933179 (rank : 34)	θ value	4.41421e-39 (rank : 35)
Query Neighborhood Hits	160	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG2_HUMAN
NC score	0.933165 (rank : 35)	θ value	2.34062e-40 (rank : 30)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARA_MOUSE
NC score	0.933084 (rank : 36)	θ value	7.52953e-39 (rank : 36)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_HUMAN
NC score	0.933020 (rank : 37)	θ value	2.34062e-40 (rank : 29)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARB_HUMAN
NC score	0.932631 (rank : 38)	θ value	7.52953e-39 (rank : 37)
Query Neighborhood Hits	160	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARG2_MOUSE
NC score	0.932626 (rank : 39)	θ value	1.98146e-39 (rank : 34)
Query Neighborhood Hits	160	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARB_MOUSE
NC score	0.932591 (rank : 40)	θ value	1.98146e-39 (rank : 32)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARG1_MOUSE
NC score	0.932336 (rank : 41)	θ value	1.98146e-39 (rank : 33)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

ESR2_HUMAN
NC score	0.932195 (rank : 42)	θ value	3.74554e-30 (rank : 53)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

TR2_MOUSE
NC score	0.930973 (rank : 43)	θ value	1.16434e-31 (rank : 46)
Query Neighborhood Hits	160	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

ESR2_MOUSE
NC score	0.930822 (rank : 44)	θ value	1.6813e-30 (rank : 50)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

TR2_HUMAN
NC score	0.928689 (rank : 45)	θ value	1.57365e-28 (rank : 57)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

ESR1_MOUSE
NC score	0.928561 (rank : 46)	θ value	2.34606e-32 (rank : 43)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
NC score	0.928482 (rank : 47)	θ value	8.06329e-33 (rank : 42)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR6A1_HUMAN
NC score	0.926638 (rank : 48)	θ value	1.86321e-21 (rank : 87)
Query Neighborhood Hits	160	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
NC score	0.925559 (rank : 49)	θ value	3.75424e-22 (rank : 80)
Query Neighborhood Hits	160	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR1H3_HUMAN
NC score	0.923489 (rank : 50)	θ value	5.22648e-32 (rank : 44)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_MOUSE
NC score	0.922248 (rank : 51)	θ value	1.16434e-31 (rank : 45)
Query Neighborhood Hits	160	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1I3_HUMAN
NC score	0.922187 (rank : 52)	θ value	1.12775e-26 (rank : 62)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR5A2_MOUSE
NC score	0.921678 (rank : 53)	θ value	3.50572e-28 (rank : 58)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR1H4_HUMAN
NC score	0.921368 (rank : 54)	θ value	7.80994e-28 (rank : 59)
Query Neighborhood Hits	160	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_MOUSE
NC score	0.920658 (rank : 55)	θ value	5.40856e-29 (rank : 56)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR5A2_HUMAN
NC score	0.918438 (rank : 56)	θ value	4.28545e-26 (rank : 63)
Query Neighborhood Hits	160	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR1I3_MOUSE
NC score	0.917588 (rank : 57)	θ value	1.05554e-24 (rank : 72)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

PPARA_HUMAN
NC score	0.915841 (rank : 58)	θ value	9.8567e-31 (rank : 48)
Query Neighborhood Hits	160	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

STF1_MOUSE
NC score	0.915578 (rank : 59)	θ value	1.42661e-21 (rank : 85)
Query Neighborhood Hits	160	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

PPARA_MOUSE
NC score	0.914873 (rank : 60)	θ value	4.89182e-30 (rank : 54)
Query Neighborhood Hits	160	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARD_HUMAN
NC score	0.914488 (rank : 61)	θ value	1.28732e-30 (rank : 49)
Query Neighborhood Hits	160	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

NR1H2_MOUSE
NC score	0.913820 (rank : 62)	θ value	1.08979e-29 (rank : 55)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

PPARD_MOUSE
NC score	0.913146 (rank : 63)	θ value	5.77852e-31 (rank : 47)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

STF1_HUMAN
NC score	0.912876 (rank : 64)	θ value	1.42661e-21 (rank : 84)
Query Neighborhood Hits	160	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

PPARG_HUMAN
NC score	0.911906 (rank : 65)	θ value	2.86786e-30 (rank : 52)
Query Neighborhood Hits	160	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR1D1_HUMAN
NC score	0.911609 (rank : 66)	θ value	1.42661e-21 (rank : 83)
Query Neighborhood Hits	160	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PPARG_MOUSE
NC score	0.911535 (rank : 67)	θ value	2.19584e-30 (rank : 51)
Query Neighborhood Hits	160	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

THA_HUMAN
NC score	0.909449 (rank : 68)	θ value	1.33217e-27 (rank : 60)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
NC score	0.909443 (rank : 69)	θ value	1.33217e-27 (rank : 61)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

NR1H2_HUMAN
NC score	0.905507 (rank : 70)	θ value	1.86321e-21 (rank : 86)
Query Neighborhood Hits	160	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

NR1D2_HUMAN
NC score	0.904800 (rank : 71)	θ value	1.09232e-21 (rank : 82)
Query Neighborhood Hits	160	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

THB2_HUMAN
NC score	0.903702 (rank : 72)	θ value	8.08199e-25 (rank : 71)
Query Neighborhood Hits	160	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.903274 (rank : 73)	θ value	8.08199e-25 (rank : 70)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1D2_MOUSE
NC score	0.902566 (rank : 74)	θ value	3.75424e-22 (rank : 79)
Query Neighborhood Hits	160	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

RORG_MOUSE
NC score	0.902022 (rank : 75)	θ value	2.12685e-25 (rank : 65)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

THB1_MOUSE
NC score	0.901910 (rank : 76)	θ value	5.23862e-24 (rank : 73)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
NC score	0.901774 (rank : 77)	θ value	5.23862e-24 (rank : 74)
Query Neighborhood Hits	160	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

RORB_HUMAN
NC score	0.899256 (rank : 78)	θ value	4.73814e-25 (rank : 68)
Query Neighborhood Hits	160	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
NC score	0.899028 (rank : 79)	θ value	4.73814e-25 (rank : 69)
Query Neighborhood Hits	160	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORG_HUMAN
NC score	0.898792 (rank : 80)	θ value	1.24688e-25 (rank : 64)
Query Neighborhood Hits	160	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

RORA_HUMAN
NC score	0.897906 (rank : 81)	θ value	3.62785e-25 (rank : 66)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
NC score	0.897877 (rank : 82)	θ value	3.62785e-25 (rank : 67)
Query Neighborhood Hits	160	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

VDR_MOUSE
NC score	0.897309 (rank : 83)	θ value	2.13179e-17 (rank : 94)
Query Neighborhood Hits	160	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_HUMAN
NC score	0.895799 (rank : 84)	θ value	2.13179e-17 (rank : 93)
Query Neighborhood Hits	160	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PXR_MOUSE
NC score	0.894664 (rank : 85)	θ value	3.07829e-16 (rank : 96)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

PXR_HUMAN
NC score	0.892596 (rank : 86)	θ value	1.38178e-16 (rank : 95)
Query Neighborhood Hits	160	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

GCR_HUMAN
NC score	0.880433 (rank : 87)	θ value	3.39556e-23 (rank : 76)
Query Neighborhood Hits	160	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_MOUSE
NC score	0.877868 (rank : 88)	θ value	7.56453e-23 (rank : 78)
Query Neighborhood Hits	160	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_HUMAN
NC score	0.876678 (rank : 89)	θ value	3.39556e-23 (rank : 75)
Query Neighborhood Hits	160	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
NC score	0.873392 (rank : 90)	θ value	4.58923e-20 (rank : 91)
Query Neighborhood Hits	160	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
NC score	0.871854 (rank : 91)	θ value	4.43474e-23 (rank : 77)
Query Neighborhood Hits	160	Target Neighborhood Hits	149	Shared Neighborhood Hits	94
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

PRGR_HUMAN
NC score	0.869424 (rank : 92)	θ value	1.86321e-21 (rank : 88)
Query Neighborhood Hits	160	Target Neighborhood Hits	163	Shared Neighborhood Hits	96
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

MCR_MOUSE
NC score	0.868120 (rank : 93)	θ value	8.36355e-22 (rank : 81)
Query Neighborhood Hits	160	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_MOUSE
NC score	0.864218 (rank : 94)	θ value	3.17815e-21 (rank : 89)
Query Neighborhood Hits	160	Target Neighborhood Hits	286	Shared Neighborhood Hits	105
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
NC score	0.646185 (rank : 95)	θ value	2.69047e-20 (rank : 90)
Query Neighborhood Hits	160	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.639195 (rank : 96)	θ value	2.5182e-18 (rank : 92)
Query Neighborhood Hits	160	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.610337 (rank : 97)	θ value	6.00763e-12 (rank : 98)
Query Neighborhood Hits	160	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.592779 (rank : 98)	θ value	6.41864e-14 (rank : 97)
Query Neighborhood Hits	160	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

CO4A5_HUMAN
NC score	0.052274 (rank : 99)	θ value	0.163984 (rank : 106)
Query Neighborhood Hits	160	Target Neighborhood Hits	383	Shared Neighborhood Hits	51
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO5A2_HUMAN
NC score	0.045797 (rank : 100)	θ value	0.00665767 (rank : 100)
Query Neighborhood Hits	160	Target Neighborhood Hits	760	Shared Neighborhood Hits	50
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO4A2_HUMAN
NC score	0.045550 (rank : 101)	θ value	0.00509761 (rank : 99)
Query Neighborhood Hits	160	Target Neighborhood Hits	454	Shared Neighborhood Hits	47
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO9A2_HUMAN
NC score	0.045328 (rank : 102)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	160	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A1_MOUSE
NC score	0.045117 (rank : 103)	θ value	0.0961366 (rank : 103)
Query Neighborhood Hits	160	Target Neighborhood Hits	477	Shared Neighborhood Hits	50
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO1A2_HUMAN
NC score	0.044432 (rank : 104)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	160	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A1_HUMAN
NC score	0.044376 (rank : 105)	θ value	0.0252991 (rank : 101)
Query Neighborhood Hits	160	Target Neighborhood Hits	425	Shared Neighborhood Hits	49
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO2A1_HUMAN
NC score	0.043200 (rank : 106)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	160	Target Neighborhood Hits	486	Shared Neighborhood Hits	51
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A2_MOUSE
NC score	0.042718 (rank : 107)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	160	Target Neighborhood Hits	492	Shared Neighborhood Hits	52
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO2A1_MOUSE
NC score	0.042605 (rank : 108)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	160	Target Neighborhood Hits	483	Shared Neighborhood Hits	49
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A4_HUMAN
NC score	0.042249 (rank : 109)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	160	Target Neighborhood Hits	440	Shared Neighborhood Hits	50
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO5A3_HUMAN
NC score	0.041657 (rank : 110)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	160	Target Neighborhood Hits	433	Shared Neighborhood Hits	49
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO4A3_HUMAN
NC score	0.040676 (rank : 111)	θ value	0.163984 (rank : 105)
Query Neighborhood Hits	160	Target Neighborhood Hits	421	Shared Neighborhood Hits	45
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A1_MOUSE
NC score	0.040536 (rank : 112)	θ value	0.21417 (rank : 108)
Query Neighborhood Hits	160	Target Neighborhood Hits	450	Shared Neighborhood Hits	48
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A1_HUMAN
NC score	0.039016 (rank : 113)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	160	Target Neighborhood Hits	420	Shared Neighborhood Hits	47
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO4A6_HUMAN
NC score	0.038984 (rank : 114)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	160	Target Neighborhood Hits	318	Shared Neighborhood Hits	45
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO1A2_MOUSE
NC score	0.038333 (rank : 115)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	160	Target Neighborhood Hits	388	Shared Neighborhood Hits	46
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A1_HUMAN
NC score	0.038097 (rank : 116)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	160	Target Neighborhood Hits	475	Shared Neighborhood Hits	50
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A3_HUMAN
NC score	0.037892 (rank : 117)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	160	Target Neighborhood Hits	361	Shared Neighborhood Hits	46
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CONA1_MOUSE
NC score	0.037743 (rank : 118)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	160	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CO9A2_MOUSE
NC score	0.037163 (rank : 119)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	160	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COBA1_HUMAN
NC score	0.035815 (rank : 120)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	160	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

C1QC_MOUSE
NC score	0.035642 (rank : 121)	θ value	0.125558 (rank : 104)
Query Neighborhood Hits	160	Target Neighborhood Hits	150	Shared Neighborhood Hits	38
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

CONA1_HUMAN
NC score	0.034671 (rank : 122)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	160	Target Neighborhood Hits	281	Shared Neighborhood Hits	43
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

COAA1_MOUSE
NC score	0.034564 (rank : 123)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	160	Target Neighborhood Hits	286	Shared Neighborhood Hits	44
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COBA1_MOUSE
NC score	0.033610 (rank : 124)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	160	Target Neighborhood Hits	487	Shared Neighborhood Hits	47
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA2_MOUSE
NC score	0.033535 (rank : 125)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	160	Target Neighborhood Hits	501	Shared Neighborhood Hits	48
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CO6A1_HUMAN
NC score	0.033083 (rank : 126)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	160	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_MOUSE
NC score	0.032565 (rank : 127)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	160	Target Neighborhood Hits	241	Shared Neighborhood Hits	39
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

BCL9_MOUSE
NC score	0.032413 (rank : 128)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	160	Target Neighborhood Hits	770	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CO7A1_HUMAN
NC score	0.029203 (rank : 129)	θ value	0.0563607 (rank : 102)
Query Neighborhood Hits	160	Target Neighborhood Hits	807	Shared Neighborhood Hits	49
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

C1QT5_MOUSE
NC score	0.029093 (rank : 130)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	160	Target Neighborhood Hits	131	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

ADIPO_HUMAN
NC score	0.023424 (rank : 131)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	160	Target Neighborhood Hits	169	Shared Neighborhood Hits	37
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

ADIPO_MOUSE
NC score	0.023168 (rank : 132)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	160	Target Neighborhood Hits	182	Shared Neighborhood Hits	37
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

COEA1_HUMAN
NC score	0.022107 (rank : 133)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	160	Target Neighborhood Hits	427	Shared Neighborhood Hits	45
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ZN385_HUMAN
NC score	0.019901 (rank : 134)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	160	Target Neighborhood Hits	614	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CEL_HUMAN
NC score	0.015545 (rank : 135)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	160	Target Neighborhood Hits	896	Shared Neighborhood Hits	42
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FCN1_MOUSE
NC score	0.013301 (rank : 136)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	160	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

PKHA6_HUMAN
NC score	0.010330 (rank : 137)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	160	Target Neighborhood Hits	556	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RMD5B_MOUSE
NC score	0.009709 (rank : 138)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	160	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YQ7	Gene names	Rmnd5b
Domain Architecture
Description	RMD5 homolog B.

RMD5B_HUMAN
NC score	0.008723 (rank : 139)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	160	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q96G75, Q6UVY7, Q9H6F6	Gene names	RMND5B
Domain Architecture
Description	RMD5 homolog B.

ERB1_HUMAN
NC score	0.008220 (rank : 140)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	160	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

PODO_HUMAN
NC score	0.007063 (rank : 141)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	160	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

OXRP_HUMAN
NC score	0.006677 (rank : 142)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	160	Target Neighborhood Hits	544	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

CXCC1_HUMAN
NC score	0.006553 (rank : 143)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	160	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

RTEL1_HUMAN
NC score	0.005490 (rank : 144)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	160	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

SI1L1_HUMAN
NC score	0.004868 (rank : 145)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	160	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

PARD3_HUMAN
NC score	0.004576 (rank : 146)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	160	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

CXCC1_MOUSE
NC score	0.004285 (rank : 147)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	160	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

ZDHC8_MOUSE
NC score	0.004153 (rank : 148)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	160	Target Neighborhood Hits	243	Shared Neighborhood Hits	29
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

PEX6_MOUSE
NC score	0.002046 (rank : 149)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	160	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

KCNH6_HUMAN
NC score	0.001753 (rank : 150)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	160	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

FA62A_HUMAN
NC score	0.000996 (rank : 151)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	160	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

CIC_HUMAN
NC score	0.000600 (rank : 152)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	160	Target Neighborhood Hits	992	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LAMC2_HUMAN
NC score	-0.000563 (rank : 153)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	160	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

BOC_HUMAN
NC score	-0.000786 (rank : 154)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	160	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

INVS_MOUSE
NC score	-0.002787 (rank : 155)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	160	Target Neighborhood Hits	609	Shared Neighborhood Hits	5
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ZN341_HUMAN
NC score	-0.005559 (rank : 156)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	160	Target Neighborhood Hits	803	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZN335_HUMAN
NC score	-0.006372 (rank : 157)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	160	Target Neighborhood Hits	973	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ULK1_HUMAN
NC score	-0.007345 (rank : 158)	θ value	1.06291 (rank : 115)
Query Neighborhood Hits	160	Target Neighborhood Hits	1121	Shared Neighborhood Hits	26
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

PKN3_MOUSE
NC score	-0.008416 (rank : 159)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	160	Target Neighborhood Hits	1009	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PCNT_HUMAN
NC score	-0.008597 (rank : 160)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	160	Target Neighborhood Hits	1551	Shared Neighborhood Hits	6
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).