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Network neighborhood for query Sequence : JADE3_MOUSE

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JADE3_MOUSE
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JADE1_HUMAN
θ value	0 (rank : 1)	NC score	0.978055 (rank : 3)
Query Neighborhood Hits	174	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	0 (rank : 2)	NC score	0.977615 (rank : 4)
Query Neighborhood Hits	174	Target Neighborhood Hits	160	Shared Neighborhood Hits	107
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_HUMAN
θ value	0 (rank : 3)	NC score	0.993938 (rank : 2)
Query Neighborhood Hits	174	Target Neighborhood Hits	148	Shared Neighborhood Hits	115
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
θ value	1.41267e-170 (rank : 5)	NC score	0.966162 (rank : 5)
Query Neighborhood Hits	174	Target Neighborhood Hits	199	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	2.11095e-166 (rank : 6)	NC score	0.917009 (rank : 6)
Query Neighborhood Hits	174	Target Neighborhood Hits	560	Shared Neighborhood Hits	105
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BRPF1_HUMAN
θ value	1.11734e-58 (rank : 7)	NC score	0.823856 (rank : 8)
Query Neighborhood Hits	174	Target Neighborhood Hits	259	Shared Neighborhood Hits	99
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD1_HUMAN
θ value	6.77864e-56 (rank : 8)	NC score	0.816273 (rank : 9)
Query Neighborhood Hits	174	Target Neighborhood Hits	188	Shared Neighborhood Hits	93
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
θ value	1.2784e-54 (rank : 9)	NC score	0.808399 (rank : 10)
Query Neighborhood Hits	174	Target Neighborhood Hits	217	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

AF10_MOUSE
θ value	8.91499e-32 (rank : 10)	NC score	0.797707 (rank : 11)
Query Neighborhood Hits	174	Target Neighborhood Hits	182	Shared Neighborhood Hits	64
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
θ value	1.52067e-31 (rank : 11)	NC score	0.795609 (rank : 12)
Query Neighborhood Hits	174	Target Neighborhood Hits	198	Shared Neighborhood Hits	64
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	4.42448e-31 (rank : 12)	NC score	0.833184 (rank : 7)
Query Neighborhood Hits	174	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

PHF14_HUMAN
θ value	1.33217e-27 (rank : 13)	NC score	0.755323 (rank : 14)
Query Neighborhood Hits	174	Target Neighborhood Hits	447	Shared Neighborhood Hits	101
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	1.33217e-27 (rank : 14)	NC score	0.768295 (rank : 13)
Query Neighborhood Hits	174	Target Neighborhood Hits	342	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

JHD3B_HUMAN
θ value	3.75424e-22 (rank : 15)	NC score	0.612120 (rank : 15)
Query Neighborhood Hits	174	Target Neighborhood Hits	128	Shared Neighborhood Hits	51
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	1.09232e-21 (rank : 16)	NC score	0.607860 (rank : 16)
Query Neighborhood Hits	174	Target Neighborhood Hits	152	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_HUMAN
θ value	4.15078e-21 (rank : 17)	NC score	0.594193 (rank : 20)
Query Neighborhood Hits	174	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3C_MOUSE
θ value	2.69047e-20 (rank : 18)	NC score	0.598799 (rank : 17)
Query Neighborhood Hits	174	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_MOUSE
θ value	5.07402e-19 (rank : 19)	NC score	0.598193 (rank : 18)
Query Neighborhood Hits	174	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_HUMAN
θ value	1.13037e-18 (rank : 20)	NC score	0.595792 (rank : 19)
Query Neighborhood Hits	174	Target Neighborhood Hits	78	Shared Neighborhood Hits	43
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

PHF1_HUMAN
θ value	7.59969e-07 (rank : 21)	NC score	0.388913 (rank : 22)
Query Neighborhood Hits	174	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	7.59969e-07 (rank : 22)	NC score	0.389031 (rank : 21)
Query Neighborhood Hits	174	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

MLL4_HUMAN
θ value	1.29631e-06 (rank : 23)	NC score	0.289704 (rank : 30)
Query Neighborhood Hits	174	Target Neighborhood Hits	722	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MTF2_HUMAN
θ value	2.88788e-06 (rank : 24)	NC score	0.382781 (rank : 24)
Query Neighborhood Hits	174	Target Neighborhood Hits	119	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	2.88788e-06 (rank : 25)	NC score	0.386369 (rank : 23)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PHF10_HUMAN
θ value	7.1131e-05 (rank : 26)	NC score	0.369287 (rank : 25)
Query Neighborhood Hits	174	Target Neighborhood Hits	151	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	9.29e-05 (rank : 27)	NC score	0.366463 (rank : 26)
Query Neighborhood Hits	174	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

BAZ2B_HUMAN
θ value	0.000461057 (rank : 28)	NC score	0.248227 (rank : 42)
Query Neighborhood Hits	174	Target Neighborhood Hits	803	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CHD4_HUMAN
θ value	0.000602161 (rank : 29)	NC score	0.182603 (rank : 84)
Query Neighborhood Hits	174	Target Neighborhood Hits	365	Shared Neighborhood Hits	91
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

TIF1B_MOUSE
θ value	0.000602161 (rank : 30)	NC score	0.216359 (rank : 67)
Query Neighborhood Hits	174	Target Neighborhood Hits	276	Shared Neighborhood Hits	67
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

CHD5_HUMAN
θ value	0.000786445 (rank : 31)	NC score	0.186609 (rank : 83)
Query Neighborhood Hits	174	Target Neighborhood Hits	349	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

NSD1_HUMAN
θ value	0.00102713 (rank : 32)	NC score	0.239417 (rank : 54)
Query Neighborhood Hits	174	Target Neighborhood Hits	427	Shared Neighborhood Hits	86
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0.00102713 (rank : 33)	NC score	0.243641 (rank : 49)
Query Neighborhood Hits	174	Target Neighborhood Hits	472	Shared Neighborhood Hits	90
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RAI1_MOUSE
θ value	0.00102713 (rank : 34)	NC score	0.223863 (rank : 62)
Query Neighborhood Hits	174	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CHD4_MOUSE
θ value	0.00134147 (rank : 35)	NC score	0.181001 (rank : 86)
Query Neighborhood Hits	174	Target Neighborhood Hits	408	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

MLL2_HUMAN
θ value	0.00175202 (rank : 36)	NC score	0.245429 (rank : 45)
Query Neighborhood Hits	174	Target Neighborhood Hits	1788	Shared Neighborhood Hits	117
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BAZ1B_HUMAN
θ value	0.00228821 (rank : 37)	NC score	0.262132 (rank : 37)
Query Neighborhood Hits	174	Target Neighborhood Hits	701	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	0.00228821 (rank : 38)	NC score	0.277345 (rank : 33)
Query Neighborhood Hits	174	Target Neighborhood Hits	394	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

TIF1G_MOUSE
θ value	0.00228821 (rank : 39)	NC score	0.201037 (rank : 79)
Query Neighborhood Hits	174	Target Neighborhood Hits	498	Shared Neighborhood Hits	74
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

HRX_HUMAN
θ value	0.00298849 (rank : 40)	NC score	0.256269 (rank : 38)
Query Neighborhood Hits	174	Target Neighborhood Hits	825	Shared Neighborhood Hits	98
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TAF3_HUMAN
θ value	0.00298849 (rank : 41)	NC score	0.207425 (rank : 70)
Query Neighborhood Hits	174	Target Neighborhood Hits	568	Shared Neighborhood Hits	91
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	0.00298849 (rank : 42)	NC score	0.202461 (rank : 78)
Query Neighborhood Hits	174	Target Neighborhood Hits	463	Shared Neighborhood Hits	79
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

AIRE_HUMAN
θ value	0.00509761 (rank : 43)	NC score	0.329471 (rank : 27)
Query Neighborhood Hits	174	Target Neighborhood Hits	144	Shared Neighborhood Hits	72
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

JAD1D_HUMAN
θ value	0.00509761 (rank : 44)	NC score	0.299485 (rank : 29)
Query Neighborhood Hits	174	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

CHD3_HUMAN
θ value	0.00665767 (rank : 45)	NC score	0.181744 (rank : 85)
Query Neighborhood Hits	174	Target Neighborhood Hits	397	Shared Neighborhood Hits	95
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

DPF1_MOUSE
θ value	0.00665767 (rank : 46)	NC score	0.254788 (rank : 39)
Query Neighborhood Hits	174	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TIF1B_HUMAN
θ value	0.00665767 (rank : 47)	NC score	0.205531 (rank : 71)
Query Neighborhood Hits	174	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

BAZ2A_HUMAN
θ value	0.00869519 (rank : 48)	NC score	0.240714 (rank : 52)
Query Neighborhood Hits	174	Target Neighborhood Hits	780	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

TIF1G_HUMAN
θ value	0.00869519 (rank : 49)	NC score	0.198057 (rank : 80)
Query Neighborhood Hits	174	Target Neighborhood Hits	410	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

AIRE_MOUSE
θ value	0.0113563 (rank : 50)	NC score	0.319545 (rank : 28)
Query Neighborhood Hits	174	Target Neighborhood Hits	196	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

K1333_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.191790 (rank : 81)
Query Neighborhood Hits	174	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

JAD1C_HUMAN
θ value	0.0148317 (rank : 52)	NC score	0.273229 (rank : 35)
Query Neighborhood Hits	174	Target Neighborhood Hits	187	Shared Neighborhood Hits	82
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.273305 (rank : 34)
Query Neighborhood Hits	174	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

MYST3_HUMAN
θ value	0.0148317 (rank : 54)	NC score	0.219763 (rank : 64)
Query Neighborhood Hits	174	Target Neighborhood Hits	772	Shared Neighborhood Hits	99
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.0148317 (rank : 55)	NC score	0.219103 (rank : 65)
Query Neighborhood Hits	174	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PHF7_HUMAN
θ value	0.0148317 (rank : 56)	NC score	0.247687 (rank : 43)
Query Neighborhood Hits	174	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

REQU_HUMAN
θ value	0.0148317 (rank : 57)	NC score	0.249106 (rank : 41)
Query Neighborhood Hits	174	Target Neighborhood Hits	523	Shared Neighborhood Hits	75
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BAZ2A_MOUSE
θ value	0.0193708 (rank : 58)	NC score	0.237782 (rank : 56)
Query Neighborhood Hits	174	Target Neighborhood Hits	744	Shared Neighborhood Hits	89
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST4_MOUSE
θ value	0.0193708 (rank : 59)	NC score	0.225226 (rank : 61)
Query Neighborhood Hits	174	Target Neighborhood Hits	416	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PHF6_HUMAN
θ value	0.0193708 (rank : 60)	NC score	0.223357 (rank : 63)
Query Neighborhood Hits	174	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

MYST4_HUMAN
θ value	0.0252991 (rank : 61)	NC score	0.216366 (rank : 66)
Query Neighborhood Hits	174	Target Neighborhood Hits	671	Shared Neighborhood Hits	101
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PHF6_MOUSE
θ value	0.0252991 (rank : 62)	NC score	0.205423 (rank : 72)
Query Neighborhood Hits	174	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_MOUSE
θ value	0.0252991 (rank : 63)	NC score	0.280183 (rank : 31)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RAI1_HUMAN
θ value	0.0252991 (rank : 64)	NC score	0.204095 (rank : 75)
Query Neighborhood Hits	174	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REQU_MOUSE
θ value	0.0252991 (rank : 65)	NC score	0.243836 (rank : 46)
Query Neighborhood Hits	174	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	0.0431538 (rank : 66)	NC score	0.246321 (rank : 44)
Query Neighborhood Hits	174	Target Neighborhood Hits	539	Shared Neighborhood Hits	89
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PHF12_HUMAN
θ value	0.0563607 (rank : 67)	NC score	0.238961 (rank : 55)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	75
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	0.0563607 (rank : 68)	NC score	0.237226 (rank : 57)
Query Neighborhood Hits	174	Target Neighborhood Hits	172	Shared Neighborhood Hits	74
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BAZ1A_HUMAN
θ value	0.0736092 (rank : 69)	NC score	0.251060 (rank : 40)
Query Neighborhood Hits	174	Target Neighborhood Hits	693	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

JAD1D_MOUSE
θ value	0.0736092 (rank : 70)	NC score	0.271906 (rank : 36)
Query Neighborhood Hits	174	Target Neighborhood Hits	228	Shared Neighborhood Hits	86
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MEOX1_HUMAN
θ value	0.0736092 (rank : 71)	NC score	0.022697 (rank : 163)
Query Neighborhood Hits	174	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	P50221	Gene names	MEOX1, MOX1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

BPTF_HUMAN
θ value	0.0961366 (rank : 72)	NC score	0.202580 (rank : 77)
Query Neighborhood Hits	174	Target Neighborhood Hits	786	Shared Neighborhood Hits	99
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CCD82_MOUSE
θ value	0.0961366 (rank : 73)	NC score	0.044615 (rank : 151)
Query Neighborhood Hits	174	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

MLL3_HUMAN
θ value	0.0961366 (rank : 74)	NC score	0.226043 (rank : 60)
Query Neighborhood Hits	174	Target Neighborhood Hits	1644	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	0.0961366 (rank : 75)	NC score	0.243667 (rank : 48)
Query Neighborhood Hits	174	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF11_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.240779 (rank : 50)
Query Neighborhood Hits	174	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

TRI66_HUMAN
θ value	0.0961366 (rank : 77)	NC score	0.213613 (rank : 69)
Query Neighborhood Hits	174	Target Neighborhood Hits	479	Shared Neighborhood Hits	75
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	0.125558 (rank : 78)	NC score	0.214617 (rank : 68)
Query Neighborhood Hits	174	Target Neighborhood Hits	491	Shared Neighborhood Hits	81
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

DPF1_HUMAN
θ value	0.163984 (rank : 79)	NC score	0.243703 (rank : 47)
Query Neighborhood Hits	174	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

EPC1_HUMAN
θ value	0.163984 (rank : 80)	NC score	0.157867 (rank : 88)
Query Neighborhood Hits	174	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

EPC1_MOUSE
θ value	0.163984 (rank : 81)	NC score	0.147008 (rank : 91)
Query Neighborhood Hits	174	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

EPC2_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.139140 (rank : 98)
Query Neighborhood Hits	174	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

EPC2_MOUSE
θ value	0.163984 (rank : 83)	NC score	0.139477 (rank : 97)
Query Neighborhood Hits	174	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

PKCB1_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.203828 (rank : 76)
Query Neighborhood Hits	174	Target Neighborhood Hits	488	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

UHRF2_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.190196 (rank : 82)
Query Neighborhood Hits	174	Target Neighborhood Hits	275	Shared Neighborhood Hits	66
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MEOX1_MOUSE
θ value	0.21417 (rank : 86)	NC score	0.023466 (rank : 161)
Query Neighborhood Hits	174	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	P32442	Gene names	Meox1, Mox-1, Mox1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

TIF1A_HUMAN
θ value	0.21417 (rank : 87)	NC score	0.205282 (rank : 73)
Query Neighborhood Hits	174	Target Neighborhood Hits	327	Shared Neighborhood Hits	75
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

APC_MOUSE
θ value	0.279714 (rank : 88)	NC score	0.036298 (rank : 154)
Query Neighborhood Hits	174	Target Neighborhood Hits	441	Shared Neighborhood Hits	21
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ITSN2_HUMAN
θ value	0.279714 (rank : 89)	NC score	0.016435 (rank : 173)
Query Neighborhood Hits	174	Target Neighborhood Hits	1173	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SRRM2_MOUSE
θ value	0.279714 (rank : 90)	NC score	0.046874 (rank : 150)
Query Neighborhood Hits	174	Target Neighborhood Hits	1470	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCF20_MOUSE
θ value	0.279714 (rank : 91)	NC score	0.146968 (rank : 92)
Query Neighborhood Hits	174	Target Neighborhood Hits	396	Shared Neighborhood Hits	46
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TIF1A_MOUSE
θ value	0.279714 (rank : 92)	NC score	0.204386 (rank : 74)
Query Neighborhood Hits	174	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

UHRF2_HUMAN
θ value	0.279714 (rank : 93)	NC score	0.171959 (rank : 87)
Query Neighborhood Hits	174	Target Neighborhood Hits	269	Shared Neighborhood Hits	68
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

APC_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.038277 (rank : 153)
Query Neighborhood Hits	174	Target Neighborhood Hits	603	Shared Neighborhood Hits	30
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PF21A_HUMAN
θ value	0.47712 (rank : 95)	NC score	0.235482 (rank : 58)
Query Neighborhood Hits	174	Target Neighborhood Hits	303	Shared Neighborhood Hits	88
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

HXA1_MOUSE
θ value	0.62314 (rank : 96)	NC score	0.010528 (rank : 192)
Query Neighborhood Hits	174	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	P09022, P15463	Gene names	Hoxa1, Era-1, Hox-1.6, Hoxa-1
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1.6) (Homeotic protein ERA-1-993) (Early retinoic acid 1) (Homeoboxless protein ERA-1-399).

K0555_HUMAN
θ value	0.62314 (rank : 97)	NC score	0.021027 (rank : 167)
Query Neighborhood Hits	174	Target Neighborhood Hits	880	Shared Neighborhood Hits	41
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KIF5C_HUMAN
θ value	0.62314 (rank : 98)	NC score	0.016434 (rank : 174)
Query Neighborhood Hits	174	Target Neighborhood Hits	974	Shared Neighborhood Hits	35
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PF21A_MOUSE
θ value	0.62314 (rank : 99)	NC score	0.234340 (rank : 59)
Query Neighborhood Hits	174	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PININ_HUMAN
θ value	0.62314 (rank : 100)	NC score	0.028192 (rank : 159)
Query Neighborhood Hits	174	Target Neighborhood Hits	753	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CTRO_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.009283 (rank : 196)
Query Neighborhood Hits	174	Target Neighborhood Hits	2344	Shared Neighborhood Hits	70
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

HXA1_HUMAN
θ value	0.813845 (rank : 102)	NC score	0.010233 (rank : 193)
Query Neighborhood Hits	174	Target Neighborhood Hits	334	Shared Neighborhood Hits	6
SwissProt Accessions	P49639, O43363	Gene names	HOXA1, HOX1F
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1F).

IFT81_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.018851 (rank : 169)
Query Neighborhood Hits	174	Target Neighborhood Hits	959	Shared Neighborhood Hits	38
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

JAD1A_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.279013 (rank : 32)
Query Neighborhood Hits	174	Target Neighborhood Hits	328	Shared Neighborhood Hits	97
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

NFH_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.043730 (rank : 152)
Query Neighborhood Hits	174	Target Neighborhood Hits	2247	Shared Neighborhood Hits	83
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCF20_HUMAN
θ value	0.813845 (rank : 106)	NC score	0.149126 (rank : 89)
Query Neighborhood Hits	174	Target Neighborhood Hits	323	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CCDC6_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.021997 (rank : 165)
Query Neighborhood Hits	174	Target Neighborhood Hits	723	Shared Neighborhood Hits	31
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

ING3_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.119537 (rank : 103)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

KIF5C_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.017762 (rank : 170)
Query Neighborhood Hits	174	Target Neighborhood Hits	1040	Shared Neighborhood Hits	40
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PHF22_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.146207 (rank : 93)
Query Neighborhood Hits	174	Target Neighborhood Hits	89	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ING3_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.115856 (rank : 104)
Query Neighborhood Hits	174	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

NFM_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.014238 (rank : 179)
Query Neighborhood Hits	174	Target Neighborhood Hits	1328	Shared Neighborhood Hits	60
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SEMG2_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.026427 (rank : 160)
Query Neighborhood Hits	174	Target Neighborhood Hits	251	Shared Neighborhood Hits	16
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

TEKT2_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.016284 (rank : 176)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

PHF20_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.082317 (rank : 122)
Query Neighborhood Hits	174	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.086865 (rank : 116)
Query Neighborhood Hits	174	Target Neighborhood Hits	513	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CCD82_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.032528 (rank : 156)
Query Neighborhood Hits	174	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

DIDO1_HUMAN
θ value	2.36792 (rank : 118)	NC score	0.059733 (rank : 139)
Query Neighborhood Hits	174	Target Neighborhood Hits	960	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GLE1_MOUSE
θ value	2.36792 (rank : 119)	NC score	0.023270 (rank : 162)
Query Neighborhood Hits	174	Target Neighborhood Hits	504	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

ITSN2_MOUSE
θ value	2.36792 (rank : 120)	NC score	0.011360 (rank : 190)
Query Neighborhood Hits	174	Target Neighborhood Hits	1371	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PLEC1_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.014184 (rank : 180)
Query Neighborhood Hits	174	Target Neighborhood Hits	1326	Shared Neighborhood Hits	51
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RP1_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.012194 (rank : 186)
Query Neighborhood Hits	174	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

CENPE_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.012086 (rank : 188)
Query Neighborhood Hits	174	Target Neighborhood Hits	2060	Shared Neighborhood Hits	65
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GLE1_HUMAN
θ value	3.0926 (rank : 124)	NC score	0.019225 (rank : 168)
Query Neighborhood Hits	174	Target Neighborhood Hits	445	Shared Neighborhood Hits	21
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

K1333_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.134273 (rank : 100)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

LRRF1_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.029043 (rank : 158)
Query Neighborhood Hits	174	Target Neighborhood Hits	625	Shared Neighborhood Hits	40
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

PRP40_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.022500 (rank : 164)
Query Neighborhood Hits	174	Target Neighborhood Hits	442	Shared Neighborhood Hits	29
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

AHTF1_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.012400 (rank : 185)
Query Neighborhood Hits	174	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

BANK1_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.012802 (rank : 184)
Query Neighborhood Hits	174	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDB2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2	Gene names	BANK1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats.

DDX21_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.006840 (rank : 203)
Query Neighborhood Hits	174	Target Neighborhood Hits	350	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

HRB2_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.013707 (rank : 182)
Query Neighborhood Hits	174	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q13601, Q8NEA8, Q8TC37, Q96AT5	Gene names	HRB2
Domain Architecture	No domain graphic available
Description	HIV-1 Rev-binding protein 2 (Rev-interacting protein 1) (Rip-1).

PININ_MOUSE
θ value	4.03905 (rank : 132)	NC score	0.030524 (rank : 157)
Query Neighborhood Hits	174	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PRP40_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.021486 (rank : 166)
Query Neighborhood Hits	174	Target Neighborhood Hits	447	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

TMM24_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.015411 (rank : 177)
Query Neighborhood Hits	174	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

CLMN_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.012091 (rank : 187)
Query Neighborhood Hits	174	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

DLG5_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.011591 (rank : 189)
Query Neighborhood Hits	174	Target Neighborhood Hits	1088	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GOGA4_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.015354 (rank : 178)
Query Neighborhood Hits	174	Target Neighborhood Hits	2034	Shared Neighborhood Hits	66
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

IP3KC_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.008296 (rank : 200)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

PKHG1_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.008956 (rank : 198)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

TSP2_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.003974 (rank : 209)
Query Neighborhood Hits	174	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ABL1_MOUSE
θ value	6.88961 (rank : 141)	NC score	-0.003953 (rank : 218)
Query Neighborhood Hits	174	Target Neighborhood Hits	1178	Shared Neighborhood Hits	16
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ADA22_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.002293 (rank : 214)
Query Neighborhood Hits	174	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.002278 (rank : 215)
Query Neighborhood Hits	174	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

BFSP1_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.007022 (rank : 202)
Query Neighborhood Hits	174	Target Neighborhood Hits	508	Shared Neighborhood Hits	21
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

CFAH_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.002662 (rank : 212)
Query Neighborhood Hits	174	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CXCC1_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.068203 (rank : 132)
Query Neighborhood Hits	174	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.066477 (rank : 134)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

ERC2_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.009898 (rank : 195)
Query Neighborhood Hits	174	Target Neighborhood Hits	1156	Shared Neighborhood Hits	44
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.010042 (rank : 194)
Query Neighborhood Hits	174	Target Neighborhood Hits	1166	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FHL1_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.013668 (rank : 183)
Query Neighborhood Hits	174	Target Neighborhood Hits	462	Shared Neighborhood Hits	12
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

HORN_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.008995 (rank : 197)
Query Neighborhood Hits	174	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

ING4_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.089106 (rank : 112)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.087987 (rank : 114)
Query Neighborhood Hits	174	Target Neighborhood Hits	93	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

IWS1_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.052421 (rank : 147)
Query Neighborhood Hits	174	Target Neighborhood Hits	1258	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRRK2_HUMAN
θ value	6.88961 (rank : 155)	NC score	-0.003848 (rank : 217)
Query Neighborhood Hits	174	Target Neighborhood Hits	1382	Shared Neighborhood Hits	7
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

NED4L_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.003632 (rank : 210)
Query Neighborhood Hits	174	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

PCNT_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.016388 (rank : 175)
Query Neighborhood Hits	174	Target Neighborhood Hits	1551	Shared Neighborhood Hits	56
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ROCK1_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.002193 (rank : 216)
Query Neighborhood Hits	174	Target Neighborhood Hits	2000	Shared Neighborhood Hits	54
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

STABP_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.008468 (rank : 199)
Query Neighborhood Hits	174	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

SYCP1_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.016578 (rank : 172)
Query Neighborhood Hits	174	Target Neighborhood Hits	1456	Shared Neighborhood Hits	59
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

UHRF1_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.145389 (rank : 94)
Query Neighborhood Hits	174	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

USP9X_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.006091 (rank : 207)
Query Neighborhood Hits	174	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.006554 (rank : 205)
Query Neighborhood Hits	174	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

ACET_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.006577 (rank : 204)
Query Neighborhood Hits	174	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P22967	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.006405 (rank : 206)
Query Neighborhood Hits	174	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

CCNT2_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.007494 (rank : 201)
Query Neighborhood Hits	174	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

NED4L_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.003300 (rank : 211)
Query Neighborhood Hits	174	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OPTN_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.014030 (rank : 181)
Query Neighborhood Hits	174	Target Neighborhood Hits	827	Shared Neighborhood Hits	42
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PHF22_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.095455 (rank : 109)
Query Neighborhood Hits	174	Target Neighborhood Hits	121	Shared Neighborhood Hits	43
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ROCK1_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.002609 (rank : 213)
Query Neighborhood Hits	174	Target Neighborhood Hits	2126	Shared Neighborhood Hits	51
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RUFY2_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.010547 (rank : 191)
Query Neighborhood Hits	174	Target Neighborhood Hits	1208	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SPTB1_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.005204 (rank : 208)
Query Neighborhood Hits	174	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SRRM2_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.033765 (rank : 155)
Query Neighborhood Hits	174	Target Neighborhood Hits	1296	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TMM24_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.017659 (rank : 171)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

ATAD2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.051481 (rank : 149)
Query Neighborhood Hits	174	Target Neighborhood Hits	322	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BRD2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.077271 (rank : 126)
Query Neighborhood Hits	174	Target Neighborhood Hits	242	Shared Neighborhood Hits	28
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.071514 (rank : 129)
Query Neighborhood Hits	174	Target Neighborhood Hits	369	Shared Neighborhood Hits	33
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.076042 (rank : 127)
Query Neighborhood Hits	174	Target Neighborhood Hits	402	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.070846 (rank : 130)
Query Neighborhood Hits	174	Target Neighborhood Hits	851	Shared Neighborhood Hits	46
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.078174 (rank : 125)
Query Neighborhood Hits	174	Target Neighborhood Hits	845	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD7_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.111138 (rank : 107)
Query Neighborhood Hits	174	Target Neighborhood Hits	94	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.108674 (rank : 108)
Query Neighborhood Hits	174	Target Neighborhood Hits	141	Shared Neighborhood Hits	22
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.086036 (rank : 119)
Query Neighborhood Hits	174	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.083939 (rank : 120)
Query Neighborhood Hits	174	Target Neighborhood Hits	422	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD9_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.113857 (rank : 105)
Query Neighborhood Hits	174	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.111923 (rank : 106)
Query Neighborhood Hits	174	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRDT_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.065894 (rank : 135)
Query Neighborhood Hits	174	Target Neighborhood Hits	280	Shared Neighborhood Hits	28
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.065696 (rank : 136)
Query Neighborhood Hits	174	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CBP_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.069161 (rank : 131)
Query Neighborhood Hits	174	Target Neighborhood Hits	941	Shared Neighborhood Hits	37
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.064170 (rank : 137)
Query Neighborhood Hits	174	Target Neighborhood Hits	1051	Shared Neighborhood Hits	39
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.086054 (rank : 118)
Query Neighborhood Hits	174	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

DPF3_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.052919 (rank : 146)
Query Neighborhood Hits	174	Target Neighborhood Hits	327	Shared Neighborhood Hits	11
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

EP300_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.067127 (rank : 133)
Query Neighborhood Hits	174	Target Neighborhood Hits	821	Shared Neighborhood Hits	37
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GCNL2_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.088153 (rank : 113)
Query Neighborhood Hits	174	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.087599 (rank : 115)
Query Neighborhood Hits	174	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

ING1_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.055536 (rank : 144)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.054561 (rank : 145)
Query Neighborhood Hits	174	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING5_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.058162 (rank : 140)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.056673 (rank : 142)
Query Neighborhood Hits	174	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

IWS1_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.052353 (rank : 148)
Query Neighborhood Hits	174	Target Neighborhood Hits	1241	Shared Neighborhood Hits	55
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JARD2_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.120003 (rank : 102)
Query Neighborhood Hits	174	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.122004 (rank : 101)
Query Neighborhood Hits	174	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3D_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.239505 (rank : 53)
Query Neighborhood Hits	174	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.240736 (rank : 51)
Query Neighborhood Hits	174	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

LY10_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.135616 (rank : 99)
Query Neighborhood Hits	174	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

PB1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.074797 (rank : 128)
Query Neighborhood Hits	174	Target Neighborhood Hits	261	Shared Neighborhood Hits	19
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCAF_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.086593 (rank : 117)
Query Neighborhood Hits	174	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PF21B_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.144118 (rank : 95)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.140042 (rank : 96)
Query Neighborhood Hits	174	Target Neighborhood Hits	278	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SET1A_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.055859 (rank : 143)
Query Neighborhood Hits	174	Target Neighborhood Hits	690	Shared Neighborhood Hits	29
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SMCA2_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.057568 (rank : 141)
Query Neighborhood Hits	174	Target Neighborhood Hits	503	Shared Neighborhood Hits	33
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.062175 (rank : 138)
Query Neighborhood Hits	174	Target Neighborhood Hits	597	Shared Neighborhood Hits	36
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SP110_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.091515 (rank : 111)
Query Neighborhood Hits	174	Target Neighborhood Hits	141	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TAF1L_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.078439 (rank : 124)
Query Neighborhood Hits	174	Target Neighborhood Hits	144	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.080859 (rank : 123)
Query Neighborhood Hits	174	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

UHRF1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.147399 (rank : 90)
Query Neighborhood Hits	174	Target Neighborhood Hits	272	Shared Neighborhood Hits	66
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ZMY11_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.082902 (rank : 121)
Query Neighborhood Hits	174	Target Neighborhood Hits	201	Shared Neighborhood Hits	60
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.093337 (rank : 110)
Query Neighborhood Hits	174	Target Neighborhood Hits	198	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

JADE3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_HUMAN
NC score	0.993938 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	174	Target Neighborhood Hits	148	Shared Neighborhood Hits	115
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE1_HUMAN
NC score	0.978055 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	174	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.977615 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	174	Target Neighborhood Hits	160	Shared Neighborhood Hits	107
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
NC score	0.966162 (rank : 5)	θ value	1.41267e-170 (rank : 5)
Query Neighborhood Hits	174	Target Neighborhood Hits	199	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
NC score	0.917009 (rank : 6)	θ value	2.11095e-166 (rank : 6)
Query Neighborhood Hits	174	Target Neighborhood Hits	560	Shared Neighborhood Hits	105
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

AF17_HUMAN
NC score	0.833184 (rank : 7)	θ value	4.42448e-31 (rank : 12)
Query Neighborhood Hits	174	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

BRPF1_HUMAN
NC score	0.823856 (rank : 8)	θ value	1.11734e-58 (rank : 7)
Query Neighborhood Hits	174	Target Neighborhood Hits	259	Shared Neighborhood Hits	99
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD1_HUMAN
NC score	0.816273 (rank : 9)	θ value	6.77864e-56 (rank : 8)
Query Neighborhood Hits	174	Target Neighborhood Hits	188	Shared Neighborhood Hits	93
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
NC score	0.808399 (rank : 10)	θ value	1.2784e-54 (rank : 9)
Query Neighborhood Hits	174	Target Neighborhood Hits	217	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

AF10_MOUSE
NC score	0.797707 (rank : 11)	θ value	8.91499e-32 (rank : 10)
Query Neighborhood Hits	174	Target Neighborhood Hits	182	Shared Neighborhood Hits	64
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
NC score	0.795609 (rank : 12)	θ value	1.52067e-31 (rank : 11)
Query Neighborhood Hits	174	Target Neighborhood Hits	198	Shared Neighborhood Hits	64
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

PHF14_MOUSE
NC score	0.768295 (rank : 13)	θ value	1.33217e-27 (rank : 14)
Query Neighborhood Hits	174	Target Neighborhood Hits	342	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.755323 (rank : 14)	θ value	1.33217e-27 (rank : 13)
Query Neighborhood Hits	174	Target Neighborhood Hits	447	Shared Neighborhood Hits	101
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

JHD3B_HUMAN
NC score	0.612120 (rank : 15)	θ value	3.75424e-22 (rank : 15)
Query Neighborhood Hits	174	Target Neighborhood Hits	128	Shared Neighborhood Hits	51
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
NC score	0.607860 (rank : 16)	θ value	1.09232e-21 (rank : 16)
Query Neighborhood Hits	174	Target Neighborhood Hits	152	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_MOUSE
NC score	0.598799 (rank : 17)	θ value	2.69047e-20 (rank : 18)
Query Neighborhood Hits	174	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_MOUSE
NC score	0.598193 (rank : 18)	θ value	5.07402e-19 (rank : 19)
Query Neighborhood Hits	174	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_HUMAN
NC score	0.595792 (rank : 19)	θ value	1.13037e-18 (rank : 20)
Query Neighborhood Hits	174	Target Neighborhood Hits	78	Shared Neighborhood Hits	43
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_HUMAN
NC score	0.594193 (rank : 20)	θ value	4.15078e-21 (rank : 17)
Query Neighborhood Hits	174	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

PHF1_MOUSE
NC score	0.389031 (rank : 21)	θ value	7.59969e-07 (rank : 22)
Query Neighborhood Hits	174	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF1_HUMAN
NC score	0.388913 (rank : 22)	θ value	7.59969e-07 (rank : 21)
Query Neighborhood Hits	174	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

MTF2_MOUSE
NC score	0.386369 (rank : 23)	θ value	2.88788e-06 (rank : 25)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_HUMAN
NC score	0.382781 (rank : 24)	θ value	2.88788e-06 (rank : 24)
Query Neighborhood Hits	174	Target Neighborhood Hits	119	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PHF10_HUMAN
NC score	0.369287 (rank : 25)	θ value	7.1131e-05 (rank : 26)
Query Neighborhood Hits	174	Target Neighborhood Hits	151	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.366463 (rank : 26)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	174	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

AIRE_HUMAN
NC score	0.329471 (rank : 27)	θ value	0.00509761 (rank : 43)
Query Neighborhood Hits	174	Target Neighborhood Hits	144	Shared Neighborhood Hits	72
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.319545 (rank : 28)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	174	Target Neighborhood Hits	196	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

JAD1D_HUMAN
NC score	0.299485 (rank : 29)	θ value	0.00509761 (rank : 44)
Query Neighborhood Hits	174	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MLL4_HUMAN
NC score	0.289704 (rank : 30)	θ value	1.29631e-06 (rank : 23)
Query Neighborhood Hits	174	Target Neighborhood Hits	722	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PHF7_MOUSE
NC score	0.280183 (rank : 31)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

JAD1A_HUMAN
NC score	0.279013 (rank : 32)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	174	Target Neighborhood Hits	328	Shared Neighborhood Hits	97
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

BAZ1B_MOUSE
NC score	0.277345 (rank : 33)	θ value	0.00228821 (rank : 38)
Query Neighborhood Hits	174	Target Neighborhood Hits	394	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

JAD1C_MOUSE
NC score	0.273305 (rank : 34)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	174	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.273229 (rank : 35)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	174	Target Neighborhood Hits	187	Shared Neighborhood Hits	82
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1D_MOUSE
NC score	0.271906 (rank : 36)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	174	Target Neighborhood Hits	228	Shared Neighborhood Hits	86
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

BAZ1B_HUMAN
NC score	0.262132 (rank : 37)	θ value	0.00228821 (rank : 37)
Query Neighborhood Hits	174	Target Neighborhood Hits	701	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

HRX_HUMAN
NC score	0.256269 (rank : 38)	θ value	0.00298849 (rank : 40)
Query Neighborhood Hits	174	Target Neighborhood Hits	825	Shared Neighborhood Hits	98
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

DPF1_MOUSE
NC score	0.254788 (rank : 39)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	174	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

BAZ1A_HUMAN
NC score	0.251060 (rank : 40)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	174	Target Neighborhood Hits	693	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

REQU_HUMAN
NC score	0.249106 (rank : 41)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	174	Target Neighborhood Hits	523	Shared Neighborhood Hits	75
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BAZ2B_HUMAN
NC score	0.248227 (rank : 42)	θ value	0.000461057 (rank : 28)
Query Neighborhood Hits	174	Target Neighborhood Hits	803	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PHF7_HUMAN
NC score	0.247687 (rank : 43)	θ value	0.0148317 (rank : 56)
Query Neighborhood Hits	174	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RSF1_HUMAN
NC score	0.246321 (rank : 44)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	174	Target Neighborhood Hits	539	Shared Neighborhood Hits	89
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MLL2_HUMAN
NC score	0.245429 (rank : 45)	θ value	0.00175202 (rank : 36)
Query Neighborhood Hits	174	Target Neighborhood Hits	1788	Shared Neighborhood Hits	117
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

REQU_MOUSE
NC score	0.243836 (rank : 46)	θ value	0.0252991 (rank : 65)
Query Neighborhood Hits	174	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

DPF1_HUMAN
NC score	0.243703 (rank : 47)	θ value	0.163984 (rank : 79)
Query Neighborhood Hits	174	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL3_MOUSE
NC score	0.243667 (rank : 48)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	174	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NSD1_MOUSE
NC score	0.243641 (rank : 49)	θ value	0.00102713 (rank : 33)
Query Neighborhood Hits	174	Target Neighborhood Hits	472	Shared Neighborhood Hits	90
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PHF11_HUMAN
NC score	0.240779 (rank : 50)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	174	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

JHD3D_MOUSE
NC score	0.240736 (rank : 51)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	174	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

BAZ2A_HUMAN
NC score	0.240714 (rank : 52)	θ value	0.00869519 (rank : 48)
Query Neighborhood Hits	174	Target Neighborhood Hits	780	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

JHD3D_HUMAN
NC score	0.239505 (rank : 53)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	174	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

NSD1_HUMAN
NC score	0.239417 (rank : 54)	θ value	0.00102713 (rank : 32)
Query Neighborhood Hits	174	Target Neighborhood Hits	427	Shared Neighborhood Hits	86
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PHF12_HUMAN
NC score	0.238961 (rank : 55)	θ value	0.0563607 (rank : 67)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	75
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BAZ2A_MOUSE
NC score	0.237782 (rank : 56)	θ value	0.0193708 (rank : 58)
Query Neighborhood Hits	174	Target Neighborhood Hits	744	Shared Neighborhood Hits	89
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PHF12_MOUSE
NC score	0.237226 (rank : 57)	θ value	0.0563607 (rank : 68)
Query Neighborhood Hits	174	Target Neighborhood Hits	172	Shared Neighborhood Hits	74
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21A_HUMAN
NC score	0.235482 (rank : 58)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	174	Target Neighborhood Hits	303	Shared Neighborhood Hits	88
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
NC score	0.234340 (rank : 59)	θ value	0.62314 (rank : 99)
Query Neighborhood Hits	174	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

MLL3_HUMAN
NC score	0.226043 (rank : 60)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	174	Target Neighborhood Hits	1644	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYST4_MOUSE
NC score	0.225226 (rank : 61)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	174	Target Neighborhood Hits	416	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RAI1_MOUSE
NC score	0.223863 (rank : 62)	θ value	0.00102713 (rank : 34)
Query Neighborhood Hits	174	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PHF6_HUMAN
NC score	0.223357 (rank : 63)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	174	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

MYST3_HUMAN
NC score	0.219763 (rank : 64)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	174	Target Neighborhood Hits	772	Shared Neighborhood Hits	99
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
NC score	0.219103 (rank : 65)	θ value	0.0148317 (rank : 55)
Query Neighborhood Hits	174	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
NC score	0.216366 (rank : 66)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	174	Target Neighborhood Hits	671	Shared Neighborhood Hits	101
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TIF1B_MOUSE
NC score	0.216359 (rank : 67)	θ value	0.000602161 (rank : 30)
Query Neighborhood Hits	174	Target Neighborhood Hits	276	Shared Neighborhood Hits	67
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI66_MOUSE
NC score	0.214617 (rank : 68)	θ value	0.125558 (rank : 78)
Query Neighborhood Hits	174	Target Neighborhood Hits	491	Shared Neighborhood Hits	81
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
NC score	0.213613 (rank : 69)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	174	Target Neighborhood Hits	479	Shared Neighborhood Hits	75
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TAF3_HUMAN
NC score	0.207425 (rank : 70)	θ value	0.00298849 (rank : 41)
Query Neighborhood Hits	174	Target Neighborhood Hits	568	Shared Neighborhood Hits	91
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TIF1B_HUMAN
NC score	0.205531 (rank : 71)	θ value	0.00665767 (rank : 47)
Query Neighborhood Hits	174	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PHF6_MOUSE
NC score	0.205423 (rank : 72)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	174	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

TIF1A_HUMAN
NC score	0.205282 (rank : 73)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	174	Target Neighborhood Hits	327	Shared Neighborhood Hits	75
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
NC score	0.204386 (rank : 74)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	174	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

RAI1_HUMAN
NC score	0.204095 (rank : 75)	θ value	0.0252991 (rank : 64)
Query Neighborhood Hits	174	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PKCB1_HUMAN
NC score	0.203828 (rank : 76)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	174	Target Neighborhood Hits	488	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BPTF_HUMAN
NC score	0.202580 (rank : 77)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	174	Target Neighborhood Hits	786	Shared Neighborhood Hits	99
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

TAF3_MOUSE
NC score	0.202461 (rank : 78)	θ value	0.00298849 (rank : 42)
Query Neighborhood Hits	174	Target Neighborhood Hits	463	Shared Neighborhood Hits	79
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TIF1G_MOUSE
NC score	0.201037 (rank : 79)	θ value	0.00228821 (rank : 39)
Query Neighborhood Hits	174	Target Neighborhood Hits	498	Shared Neighborhood Hits	74
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.198057 (rank : 80)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	174	Target Neighborhood Hits	410	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

K1333_MOUSE
NC score	0.191790 (rank : 81)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	174	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

UHRF2_MOUSE
NC score	0.190196 (rank : 82)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	174	Target Neighborhood Hits	275	Shared Neighborhood Hits	66
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

CHD5_HUMAN
NC score	0.186609 (rank : 83)	θ value	0.000786445 (rank : 31)
Query Neighborhood Hits	174	Target Neighborhood Hits	349	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_HUMAN
NC score	0.182603 (rank : 84)	θ value	0.000602161 (rank : 29)
Query Neighborhood Hits	174	Target Neighborhood Hits	365	Shared Neighborhood Hits	91
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD3_HUMAN
NC score	0.181744 (rank : 85)	θ value	0.00665767 (rank : 45)
Query Neighborhood Hits	174	Target Neighborhood Hits	397	Shared Neighborhood Hits	95
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_MOUSE
NC score	0.181001 (rank : 86)	θ value	0.00134147 (rank : 35)
Query Neighborhood Hits	174	Target Neighborhood Hits	408	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

UHRF2_HUMAN
NC score	0.171959 (rank : 87)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	174	Target Neighborhood Hits	269	Shared Neighborhood Hits	68
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

EPC1_HUMAN
NC score	0.157867 (rank : 88)	θ value	0.163984 (rank : 80)
Query Neighborhood Hits	174	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

TCF20_HUMAN
NC score	0.149126 (rank : 89)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	174	Target Neighborhood Hits	323	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

UHRF1_HUMAN
NC score	0.147399 (rank : 90)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	174	Target Neighborhood Hits	272	Shared Neighborhood Hits	66
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

EPC1_MOUSE
NC score	0.147008 (rank : 91)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	174	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

TCF20_MOUSE
NC score	0.146968 (rank : 92)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	174	Target Neighborhood Hits	396	Shared Neighborhood Hits	46
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PHF22_MOUSE
NC score	0.146207 (rank : 93)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	174	Target Neighborhood Hits	89	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

UHRF1_MOUSE
NC score	0.145389 (rank : 94)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	174	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PF21B_HUMAN
NC score	0.144118 (rank : 95)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
NC score	0.140042 (rank : 96)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	174	Target Neighborhood Hits	278	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

EPC2_MOUSE
NC score	0.139477 (rank : 97)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	174	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

EPC2_HUMAN
NC score	0.139140 (rank : 98)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	174	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

LY10_HUMAN
NC score	0.135616 (rank : 99)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	174	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

K1333_HUMAN
NC score	0.134273 (rank : 100)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

JARD2_MOUSE
NC score	0.122004 (rank : 101)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	174	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_HUMAN
NC score	0.120003 (rank : 102)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	174	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

ING3_MOUSE
NC score	0.119537 (rank : 103)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_HUMAN
NC score	0.115856 (rank : 104)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	174	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

BRD9_HUMAN
NC score	0.113857 (rank : 105)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	174	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
NC score	0.111923 (rank : 106)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	174	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD7_HUMAN
NC score	0.111138 (rank : 107)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	174	Target Neighborhood Hits	94	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
NC score	0.108674 (rank : 108)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	174	Target Neighborhood Hits	141	Shared Neighborhood Hits	22
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

PHF22_HUMAN
NC score	0.095455 (rank : 109)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	174	Target Neighborhood Hits	121	Shared Neighborhood Hits	43
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ZMY11_MOUSE
NC score	0.093337 (rank : 110)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	174	Target Neighborhood Hits	198	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

SP110_HUMAN
NC score	0.091515 (rank : 111)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	174	Target Neighborhood Hits	141	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

ING4_HUMAN
NC score	0.089106 (rank : 112)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

GCNL2_HUMAN
NC score	0.088153 (rank : 113)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	174	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

ING4_MOUSE
NC score	0.087987 (rank : 114)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	174	Target Neighborhood Hits	93	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

GCNL2_MOUSE
NC score	0.087599 (rank : 115)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	174	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

PHF20_MOUSE
NC score	0.086865 (rank : 116)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	174	Target Neighborhood Hits	513	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PCAF_HUMAN
NC score	0.086593 (rank : 117)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	174	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

CECR2_HUMAN
NC score	0.086054 (rank : 118)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	174	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BRD8_HUMAN
NC score	0.086036 (rank : 119)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	174	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
NC score	0.083939 (rank : 120)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	174	Target Neighborhood Hits	422	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ZMY11_HUMAN
NC score	0.082902 (rank : 121)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	174	Target Neighborhood Hits	201	Shared Neighborhood Hits	60
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PHF20_HUMAN
NC score	0.082317 (rank : 122)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	174	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

TAF1_HUMAN
NC score	0.080859 (rank : 123)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	174	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TAF1L_HUMAN
NC score	0.078439 (rank : 124)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	174	Target Neighborhood Hits	144	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

BRD4_MOUSE
NC score	0.078174 (rank : 125)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	174	Target Neighborhood Hits	845	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD2_HUMAN
NC score	0.077271 (rank : 126)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	174	Target Neighborhood Hits	242	Shared Neighborhood Hits	28
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_MOUSE
NC score	0.076042 (rank : 127)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	174	Target Neighborhood Hits	402	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

PB1_HUMAN
NC score	0.074797 (rank : 128)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	174	Target Neighborhood Hits	261	Shared Neighborhood Hits	19
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

BRD3_HUMAN
NC score	0.071514 (rank : 129)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	174	Target Neighborhood Hits	369	Shared Neighborhood Hits	33
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD4_HUMAN
NC score	0.070846 (rank : 130)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	174	Target Neighborhood Hits	851	Shared Neighborhood Hits	46
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CBP_HUMAN
NC score	0.069161 (rank : 131)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	174	Target Neighborhood Hits	941	Shared Neighborhood Hits	37
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CXCC1_HUMAN
NC score	0.068203 (rank : 132)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	174	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

EP300_HUMAN
NC score	0.067127 (rank : 133)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	174	Target Neighborhood Hits	821	Shared Neighborhood Hits	37
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CXCC1_MOUSE
NC score	0.066477 (rank : 134)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

BRDT_HUMAN
NC score	0.065894 (rank : 135)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	174	Target Neighborhood Hits	280	Shared Neighborhood Hits	28
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
NC score	0.065696 (rank : 136)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	174	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CBP_MOUSE
NC score	0.064170 (rank : 137)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	174	Target Neighborhood Hits	1051	Shared Neighborhood Hits	39
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SMCA4_HUMAN
NC score	0.062175 (rank : 138)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	174	Target Neighborhood Hits	597	Shared Neighborhood Hits	36
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

DIDO1_HUMAN
NC score	0.059733 (rank : 139)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	174	Target Neighborhood Hits	960	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ING5_HUMAN
NC score	0.058162 (rank : 140)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

SMCA2_HUMAN
NC score	0.057568 (rank : 141)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	174	Target Neighborhood Hits	503	Shared Neighborhood Hits	33
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ING5_MOUSE
NC score	0.056673 (rank : 142)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	174	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

SET1A_HUMAN
NC score	0.055859 (rank : 143)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	174	Target Neighborhood Hits	690	Shared Neighborhood Hits	29
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ING1_HUMAN
NC score	0.055536 (rank : 144)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
NC score	0.054561 (rank : 145)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	174	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

DPF3_MOUSE
NC score	0.052919 (rank : 146)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	174	Target Neighborhood Hits	327	Shared Neighborhood Hits	11
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

IWS1_MOUSE
NC score	0.052421 (rank : 147)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	174	Target Neighborhood Hits	1258	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_HUMAN
NC score	0.052353 (rank : 148)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	174	Target Neighborhood Hits	1241	Shared Neighborhood Hits	55
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ATAD2_HUMAN
NC score	0.051481 (rank : 149)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	174	Target Neighborhood Hits	322	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SRRM2_MOUSE
NC score	0.046874 (rank : 150)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	174	Target Neighborhood Hits	1470	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CCD82_MOUSE
NC score	0.044615 (rank : 151)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	174	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

NFH_MOUSE
NC score	0.043730 (rank : 152)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	174	Target Neighborhood Hits	2247	Shared Neighborhood Hits	83
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

APC_HUMAN
NC score	0.038277 (rank : 153)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	174	Target Neighborhood Hits	603	Shared Neighborhood Hits	30
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
NC score	0.036298 (rank : 154)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	174	Target Neighborhood Hits	441	Shared Neighborhood Hits	21
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SRRM2_HUMAN
NC score	0.033765 (rank : 155)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	174	Target Neighborhood Hits	1296	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CCD82_HUMAN
NC score	0.032528 (rank : 156)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	174	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

PININ_MOUSE
NC score	0.030524 (rank : 157)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	174	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

LRRF1_HUMAN
NC score	0.029043 (rank : 158)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	174	Target Neighborhood Hits	625	Shared Neighborhood Hits	40
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

PININ_HUMAN
NC score	0.028192 (rank : 159)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	174	Target Neighborhood Hits	753	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SEMG2_HUMAN
NC score	0.026427 (rank : 160)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	174	Target Neighborhood Hits	251	Shared Neighborhood Hits	16
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

MEOX1_MOUSE
NC score	0.023466 (rank : 161)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	174	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	P32442	Gene names	Meox1, Mox-1, Mox1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

GLE1_MOUSE
NC score	0.023270 (rank : 162)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	174	Target Neighborhood Hits	504	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

MEOX1_HUMAN
NC score	0.022697 (rank : 163)	θ value	0.0736092 (rank : 71)
Query Neighborhood Hits	174	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	P50221	Gene names	MEOX1, MOX1
Domain Architecture
Description	Homeobox protein MOX-1 (Mesenchyme homeobox 1).

PRP40_HUMAN
NC score	0.022500 (rank : 164)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	174	Target Neighborhood Hits	442	Shared Neighborhood Hits	29
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

CCDC6_HUMAN
NC score	0.021997 (rank : 165)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	174	Target Neighborhood Hits	723	Shared Neighborhood Hits	31
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

PRP40_MOUSE
NC score	0.021486 (rank : 166)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	174	Target Neighborhood Hits	447	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

K0555_HUMAN
NC score	0.021027 (rank : 167)	θ value	0.62314 (rank : 97)
Query Neighborhood Hits	174	Target Neighborhood Hits	880	Shared Neighborhood Hits	41
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

GLE1_HUMAN
NC score	0.019225 (rank : 168)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	174	Target Neighborhood Hits	445	Shared Neighborhood Hits	21
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

IFT81_MOUSE
NC score	0.018851 (rank : 169)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	174	Target Neighborhood Hits	959	Shared Neighborhood Hits	38
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

KIF5C_MOUSE
NC score	0.017762 (rank : 170)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	174	Target Neighborhood Hits	1040	Shared Neighborhood Hits	40
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

TMM24_MOUSE
NC score	0.017659 (rank : 171)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	174	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

SYCP1_MOUSE
NC score	0.016578 (rank : 172)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	174	Target Neighborhood Hits	1456	Shared Neighborhood Hits	59
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ITSN2_HUMAN
NC score	0.016435 (rank : 173)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	174	Target Neighborhood Hits	1173	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KIF5C_HUMAN
NC score	0.016434 (rank : 174)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	174	Target Neighborhood Hits	974	Shared Neighborhood Hits	35
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PCNT_HUMAN
NC score	0.016388 (rank : 175)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	174	Target Neighborhood Hits	1551	Shared Neighborhood Hits	56
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TEKT2_HUMAN
NC score	0.016284 (rank : 176)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

TMM24_HUMAN
NC score	0.015411 (rank : 177)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	174	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

GOGA4_HUMAN
NC score	0.015354 (rank : 178)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	174	Target Neighborhood Hits	2034	Shared Neighborhood Hits	66
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

NFM_HUMAN
NC score	0.014238 (rank : 179)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	174	Target Neighborhood Hits	1328	Shared Neighborhood Hits	60
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PLEC1_HUMAN
NC score	0.014184 (rank : 180)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	174	Target Neighborhood Hits	1326	Shared Neighborhood Hits	51
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

OPTN_HUMAN
NC score	0.014030 (rank : 181)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	174	Target Neighborhood Hits	827	Shared Neighborhood Hits	42
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

HRB2_HUMAN
NC score	0.013707 (rank : 182)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	174	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q13601, Q8NEA8, Q8TC37, Q96AT5	Gene names	HRB2
Domain Architecture	No domain graphic available
Description	HIV-1 Rev-binding protein 2 (Rev-interacting protein 1) (Rip-1).

FHL1_MOUSE
NC score	0.013668 (rank : 183)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	174	Target Neighborhood Hits	462	Shared Neighborhood Hits	12
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

BANK1_HUMAN
NC score	0.012802 (rank : 184)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	174	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDB2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2	Gene names	BANK1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats.

AHTF1_MOUSE
NC score	0.012400 (rank : 185)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	174	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

RP1_MOUSE
NC score	0.012194 (rank : 186)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	174	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

CLMN_HUMAN
NC score	0.012091 (rank : 187)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	174	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CENPE_HUMAN
NC score	0.012086 (rank : 188)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	174	Target Neighborhood Hits	2060	Shared Neighborhood Hits	65
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DLG5_HUMAN
NC score	0.011591 (rank : 189)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	174	Target Neighborhood Hits	1088	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

ITSN2_MOUSE
NC score	0.011360 (rank : 190)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	174	Target Neighborhood Hits	1371	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RUFY2_HUMAN
NC score	0.010547 (rank : 191)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	174	Target Neighborhood Hits	1208	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

HXA1_MOUSE
NC score	0.010528 (rank : 192)	θ value	0.62314 (rank : 96)
Query Neighborhood Hits	174	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	P09022, P15463	Gene names	Hoxa1, Era-1, Hox-1.6, Hoxa-1
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1.6) (Homeotic protein ERA-1-993) (Early retinoic acid 1) (Homeoboxless protein ERA-1-399).

HXA1_HUMAN
NC score	0.010233 (rank : 193)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	174	Target Neighborhood Hits	334	Shared Neighborhood Hits	6
SwissProt Accessions	P49639, O43363	Gene names	HOXA1, HOX1F
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1F).

ERC2_MOUSE
NC score	0.010042 (rank : 194)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	174	Target Neighborhood Hits	1166	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ERC2_HUMAN
NC score	0.009898 (rank : 195)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	174	Target Neighborhood Hits	1156	Shared Neighborhood Hits	44
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CTRO_MOUSE
NC score	0.009283 (rank : 196)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	174	Target Neighborhood Hits	2344	Shared Neighborhood Hits	70
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

HORN_MOUSE
NC score	0.008995 (rank : 197)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	174	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PKHG1_HUMAN
NC score	0.008956 (rank : 198)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

STABP_HUMAN
NC score	0.008468 (rank : 199)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	174	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

IP3KC_HUMAN
NC score	0.008296 (rank : 200)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

CCNT2_HUMAN
NC score	0.007494 (rank : 201)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	174	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

BFSP1_HUMAN
NC score	0.007022 (rank : 202)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	174	Target Neighborhood Hits	508	Shared Neighborhood Hits	21
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

DDX21_MOUSE
NC score	0.006840 (rank : 203)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	174	Target Neighborhood Hits	350	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

ACET_MOUSE
NC score	0.006577 (rank : 204)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	174	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P22967	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

USP9X_MOUSE
NC score	0.006554 (rank : 205)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	174	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

ACE_MOUSE
NC score	0.006405 (rank : 206)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	174	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

USP9X_HUMAN
NC score	0.006091 (rank : 207)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	174	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

SPTB1_MOUSE
NC score	0.005204 (rank : 208)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	174	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

TSP2_MOUSE
NC score	0.003974 (rank : 209)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	174	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

NED4L_MOUSE
NC score	0.003632 (rank : 210)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	174	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.003300 (rank : 211)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	174	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

CFAH_MOUSE
NC score	0.002662 (rank : 212)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	174	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

ROCK1_MOUSE
NC score	0.002609 (rank : 213)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	174	Target Neighborhood Hits	2126	Shared Neighborhood Hits	51
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ADA22_HUMAN
NC score	0.002293 (rank : 214)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	174	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
NC score	0.002278 (rank : 215)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	174	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ROCK1_HUMAN
NC score	0.002193 (rank : 216)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	174	Target Neighborhood Hits	2000	Shared Neighborhood Hits	54
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

LRRK2_HUMAN
NC score	-0.003848 (rank : 217)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	174	Target Neighborhood Hits	1382	Shared Neighborhood Hits	7
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

ABL1_MOUSE
NC score	-0.003953 (rank : 218)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	174	Target Neighborhood Hits	1178	Shared Neighborhood Hits	16
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).