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Network neighborhood for query Sequence : TAF1_HUMAN

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TAF1_HUMAN
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TAF1L_HUMAN
θ value	0 (rank : 1)	NC score	0.985583 (rank : 2)
Query Neighborhood Hits	136	Target Neighborhood Hits	144	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	136	Target Neighborhood Hits	136	Shared Neighborhood Hits	136
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

CECR2_HUMAN
θ value	1.68911e-14 (rank : 3)	NC score	0.566963 (rank : 6)
Query Neighborhood Hits	136	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

GCNL2_HUMAN
θ value	4.16044e-13 (rank : 4)	NC score	0.584216 (rank : 4)
Query Neighborhood Hits	136	Target Neighborhood Hits	159	Shared Neighborhood Hits	47
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

PB1_HUMAN
θ value	4.16044e-13 (rank : 5)	NC score	0.547220 (rank : 12)
Query Neighborhood Hits	136	Target Neighborhood Hits	261	Shared Neighborhood Hits	49
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

GCNL2_MOUSE
θ value	7.09661e-13 (rank : 6)	NC score	0.581118 (rank : 5)
Query Neighborhood Hits	136	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

PKCB1_HUMAN
θ value	2.28291e-11 (rank : 7)	NC score	0.449113 (rank : 26)
Query Neighborhood Hits	136	Target Neighborhood Hits	488	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PCAF_HUMAN
θ value	6.64225e-11 (rank : 8)	NC score	0.597178 (rank : 3)
Query Neighborhood Hits	136	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BAZ2B_HUMAN
θ value	8.67504e-11 (rank : 9)	NC score	0.467406 (rank : 21)
Query Neighborhood Hits	136	Target Neighborhood Hits	803	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD3_HUMAN
θ value	1.133e-10 (rank : 10)	NC score	0.563868 (rank : 8)
Query Neighborhood Hits	136	Target Neighborhood Hits	369	Shared Neighborhood Hits	68
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	1.133e-10 (rank : 11)	NC score	0.559604 (rank : 9)
Query Neighborhood Hits	136	Target Neighborhood Hits	402	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRDT_HUMAN
θ value	2.52405e-10 (rank : 12)	NC score	0.555661 (rank : 10)
Query Neighborhood Hits	136	Target Neighborhood Hits	280	Shared Neighborhood Hits	70
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BAZ1A_HUMAN
θ value	2.13673e-09 (rank : 13)	NC score	0.474974 (rank : 20)
Query Neighborhood Hits	136	Target Neighborhood Hits	693	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CBP_MOUSE
θ value	2.13673e-09 (rank : 14)	NC score	0.415551 (rank : 31)
Query Neighborhood Hits	136	Target Neighborhood Hits	1051	Shared Neighborhood Hits	59
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BRPF3_HUMAN
θ value	2.79066e-09 (rank : 15)	NC score	0.399627 (rank : 34)
Query Neighborhood Hits	136	Target Neighborhood Hits	217	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BPTF_HUMAN
θ value	3.64472e-09 (rank : 16)	NC score	0.454596 (rank : 24)
Query Neighborhood Hits	136	Target Neighborhood Hits	786	Shared Neighborhood Hits	71
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD4_HUMAN
θ value	4.76016e-09 (rank : 17)	NC score	0.503623 (rank : 17)
Query Neighborhood Hits	136	Target Neighborhood Hits	851	Shared Neighborhood Hits	73
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	4.76016e-09 (rank : 18)	NC score	0.500925 (rank : 18)
Query Neighborhood Hits	136	Target Neighborhood Hits	845	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRDT_MOUSE
θ value	6.21693e-09 (rank : 19)	NC score	0.547300 (rank : 11)
Query Neighborhood Hits	136	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CBP_HUMAN
θ value	6.21693e-09 (rank : 20)	NC score	0.427829 (rank : 28)
Query Neighborhood Hits	136	Target Neighborhood Hits	941	Shared Neighborhood Hits	56
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BRD2_HUMAN
θ value	8.11959e-09 (rank : 21)	NC score	0.566557 (rank : 7)
Query Neighborhood Hits	136	Target Neighborhood Hits	242	Shared Neighborhood Hits	56
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BAZ1B_MOUSE
θ value	1.38499e-08 (rank : 22)	NC score	0.461027 (rank : 23)
Query Neighborhood Hits	136	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BRD7_MOUSE
θ value	1.80886e-08 (rank : 23)	NC score	0.527994 (rank : 14)
Query Neighborhood Hits	136	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD7_HUMAN
θ value	2.36244e-08 (rank : 24)	NC score	0.535102 (rank : 13)
Query Neighborhood Hits	136	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRWD1_HUMAN
θ value	2.36244e-08 (rank : 25)	NC score	0.288989 (rank : 41)
Query Neighborhood Hits	136	Target Neighborhood Hits	448	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BAZ1B_HUMAN
θ value	4.0297e-08 (rank : 26)	NC score	0.425578 (rank : 30)
Query Neighborhood Hits	136	Target Neighborhood Hits	701	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ2A_MOUSE
θ value	4.0297e-08 (rank : 27)	NC score	0.444849 (rank : 27)
Query Neighborhood Hits	136	Target Neighborhood Hits	744	Shared Neighborhood Hits	70
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ATAD2_HUMAN
θ value	5.26297e-08 (rank : 28)	NC score	0.259459 (rank : 45)
Query Neighborhood Hits	136	Target Neighborhood Hits	322	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BAZ2A_HUMAN
θ value	5.26297e-08 (rank : 29)	NC score	0.452369 (rank : 25)
Query Neighborhood Hits	136	Target Neighborhood Hits	780	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

EP300_HUMAN
θ value	5.26297e-08 (rank : 30)	NC score	0.425684 (rank : 29)
Query Neighborhood Hits	136	Target Neighborhood Hits	821	Shared Neighborhood Hits	56
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

TIF1A_HUMAN
θ value	1.99992e-07 (rank : 31)	NC score	0.404111 (rank : 33)
Query Neighborhood Hits	136	Target Neighborhood Hits	327	Shared Neighborhood Hits	56
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	3.41135e-07 (rank : 32)	NC score	0.408618 (rank : 32)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	53
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BRD9_HUMAN
θ value	5.81887e-07 (rank : 33)	NC score	0.525218 (rank : 15)
Query Neighborhood Hits	136	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

ATAD2_MOUSE
θ value	7.59969e-07 (rank : 34)	NC score	0.257247 (rank : 46)
Query Neighborhood Hits	136	Target Neighborhood Hits	167	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BRD1_HUMAN
θ value	7.59969e-07 (rank : 35)	NC score	0.374093 (rank : 37)
Query Neighborhood Hits	136	Target Neighborhood Hits	188	Shared Neighborhood Hits	49
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRD8_HUMAN
θ value	7.59969e-07 (rank : 36)	NC score	0.497396 (rank : 19)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRPF1_HUMAN
θ value	7.59969e-07 (rank : 37)	NC score	0.355745 (rank : 38)
Query Neighborhood Hits	136	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD9_MOUSE
θ value	9.92553e-07 (rank : 38)	NC score	0.523453 (rank : 16)
Query Neighborhood Hits	136	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRWD1_MOUSE
θ value	9.92553e-07 (rank : 39)	NC score	0.278703 (rank : 42)
Query Neighborhood Hits	136	Target Neighborhood Hits	478	Shared Neighborhood Hits	51
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRD8_MOUSE
θ value	6.43352e-06 (rank : 40)	NC score	0.462448 (rank : 22)
Query Neighborhood Hits	136	Target Neighborhood Hits	422	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

TRI66_MOUSE
θ value	8.40245e-06 (rank : 41)	NC score	0.379542 (rank : 36)
Query Neighborhood Hits	136	Target Neighborhood Hits	491	Shared Neighborhood Hits	61
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
θ value	1.09739e-05 (rank : 42)	NC score	0.381435 (rank : 35)
Query Neighborhood Hits	136	Target Neighborhood Hits	479	Shared Neighborhood Hits	59
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1G_HUMAN
θ value	3.19293e-05 (rank : 43)	NC score	0.340487 (rank : 39)
Query Neighborhood Hits	136	Target Neighborhood Hits	410	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	4.1701e-05 (rank : 44)	NC score	0.335193 (rank : 40)
Query Neighborhood Hits	136	Target Neighborhood Hits	498	Shared Neighborhood Hits	56
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SMCA4_HUMAN
θ value	0.000786445 (rank : 45)	NC score	0.183175 (rank : 49)
Query Neighborhood Hits	136	Target Neighborhood Hits	597	Shared Neighborhood Hits	67
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA2_HUMAN
θ value	0.00102713 (rank : 46)	NC score	0.183527 (rank : 48)
Query Neighborhood Hits	136	Target Neighborhood Hits	503	Shared Neighborhood Hits	63
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ZMY11_HUMAN
θ value	0.00298849 (rank : 47)	NC score	0.278356 (rank : 44)
Query Neighborhood Hits	136	Target Neighborhood Hits	201	Shared Neighborhood Hits	43
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	0.00298849 (rank : 48)	NC score	0.278396 (rank : 43)
Query Neighborhood Hits	136	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

LEO1_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.059557 (rank : 97)
Query Neighborhood Hits	136	Target Neighborhood Hits	946	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

GCC2_MOUSE
θ value	0.0961366 (rank : 50)	NC score	0.050743 (rank : 113)
Query Neighborhood Hits	136	Target Neighborhood Hits	1619	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

LY10_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.202731 (rank : 47)
Query Neighborhood Hits	136	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MY18A_MOUSE
θ value	0.0961366 (rank : 52)	NC score	0.047900 (rank : 116)
Query Neighborhood Hits	136	Target Neighborhood Hits	1989	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_HUMAN
θ value	0.125558 (rank : 53)	NC score	0.047001 (rank : 117)
Query Neighborhood Hits	136	Target Neighborhood Hits	1929	Shared Neighborhood Hits	73
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD41_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.052469 (rank : 111)
Query Neighborhood Hits	136	Target Neighborhood Hits	1139	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

UACA_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.035434 (rank : 137)
Query Neighborhood Hits	136	Target Neighborhood Hits	1620	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

LIPA2_MOUSE
θ value	0.279714 (rank : 56)	NC score	0.035853 (rank : 136)
Query Neighborhood Hits	136	Target Neighborhood Hits	1282	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CEP72_MOUSE
θ value	0.365318 (rank : 57)	NC score	0.054886 (rank : 107)
Query Neighborhood Hits	136	Target Neighborhood Hits	381	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

STK10_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.025402 (rank : 153)
Query Neighborhood Hits	136	Target Neighborhood Hits	2132	Shared Neighborhood Hits	65
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MRCKB_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.022311 (rank : 159)
Query Neighborhood Hits	136	Target Neighborhood Hits	2239	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SPTA2_HUMAN
θ value	0.47712 (rank : 60)	NC score	0.027050 (rank : 150)
Query Neighborhood Hits	136	Target Neighborhood Hits	888	Shared Neighborhood Hits	33
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SUHW4_MOUSE
θ value	0.47712 (rank : 61)	NC score	0.007522 (rank : 180)
Query Neighborhood Hits	136	Target Neighborhood Hits	737	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

WRN_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.023699 (rank : 156)
Query Neighborhood Hits	136	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

ZCHC6_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.051039 (rank : 112)
Query Neighborhood Hits	136	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

OGFR_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.029394 (rank : 147)
Query Neighborhood Hits	136	Target Neighborhood Hits	584	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

CCD46_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.042603 (rank : 121)
Query Neighborhood Hits	136	Target Neighborhood Hits	1430	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

LEO1_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.055469 (rank : 105)
Query Neighborhood Hits	136	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PPCT_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.045565 (rank : 119)
Query Neighborhood Hits	136	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P53808, Q9QZX0, Q9R058	Gene names	Pctp, Stard2
Domain Architecture
Description	Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2).

TMF1_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.042594 (rank : 122)
Query Neighborhood Hits	136	Target Neighborhood Hits	987	Shared Neighborhood Hits	47
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

FLIP1_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.039997 (rank : 126)
Query Neighborhood Hits	136	Target Neighborhood Hits	1405	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GCC2_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.049092 (rank : 115)
Query Neighborhood Hits	136	Target Neighborhood Hits	1558	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RASK_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.005835 (rank : 186)
Query Neighborhood Hits	136	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	P32883, P04200, P08643	Gene names	Kras, Kras2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

RBP24_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.049174 (rank : 114)
Query Neighborhood Hits	136	Target Neighborhood Hits	1559	Shared Neighborhood Hits	55
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

WDHD1_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.027769 (rank : 148)
Query Neighborhood Hits	136	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

UBP13_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.026265 (rank : 151)
Query Neighborhood Hits	136	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

BPA1_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.032233 (rank : 140)
Query Neighborhood Hits	136	Target Neighborhood Hits	1477	Shared Neighborhood Hits	60
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GAS8_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.034529 (rank : 138)
Query Neighborhood Hits	136	Target Neighborhood Hits	819	Shared Neighborhood Hits	40
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RASK_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.005154 (rank : 188)
Query Neighborhood Hits	136	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	P01116, P01118, Q96D10	Gene names	KRAS, KRAS2, RASK2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

TEX2_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.037026 (rank : 134)
Query Neighborhood Hits	136	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ZN638_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.027264 (rank : 149)
Query Neighborhood Hits	136	Target Neighborhood Hits	318	Shared Neighborhood Hits	20
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

IFT74_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.042543 (rank : 123)
Query Neighborhood Hits	136	Target Neighborhood Hits	949	Shared Neighborhood Hits	44
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

JIP3_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.031218 (rank : 143)
Query Neighborhood Hits	136	Target Neighborhood Hits	759	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

K0831_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.038143 (rank : 131)
Query Neighborhood Hits	136	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MD1L1_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.038084 (rank : 132)
Query Neighborhood Hits	136	Target Neighborhood Hits	893	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MYST4_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.098756 (rank : 60)
Query Neighborhood Hits	136	Target Neighborhood Hits	671	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	2.36792 (rank : 85)	NC score	0.092631 (rank : 61)
Query Neighborhood Hits	136	Target Neighborhood Hits	416	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PVRL2_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.021735 (rank : 160)
Query Neighborhood Hits	136	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

STK10_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.017651 (rank : 166)
Query Neighborhood Hits	136	Target Neighborhood Hits	1921	Shared Neighborhood Hits	59
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SYNE2_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.031281 (rank : 142)
Query Neighborhood Hits	136	Target Neighborhood Hits	1323	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ABCAD_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.007003 (rank : 181)
Query Neighborhood Hits	136	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ACINU_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.056897 (rank : 103)
Query Neighborhood Hits	136	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BICD1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.031507 (rank : 141)
Query Neighborhood Hits	136	Target Neighborhood Hits	837	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

STX1B_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.019235 (rank : 163)
Query Neighborhood Hits	136	Target Neighborhood Hits	252	Shared Neighborhood Hits	22
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

ZCHC6_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.042466 (rank : 124)
Query Neighborhood Hits	136	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

GOGA3_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.039536 (rank : 128)
Query Neighborhood Hits	136	Target Neighborhood Hits	1437	Shared Neighborhood Hits	59
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GRIP1_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.009354 (rank : 178)
Query Neighborhood Hits	136	Target Neighborhood Hits	241	Shared Neighborhood Hits	6
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

HS70L_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.005336 (rank : 187)
Query Neighborhood Hits	136	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

LAP4_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.003019 (rank : 189)
Query Neighborhood Hits	136	Target Neighborhood Hits	590	Shared Neighborhood Hits	8
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

TNIP3_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.038217 (rank : 130)
Query Neighborhood Hits	136	Target Neighborhood Hits	511	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

XRCC4_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.069607 (rank : 90)
Query Neighborhood Hits	136	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

CP250_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.037373 (rank : 133)
Query Neighborhood Hits	136	Target Neighborhood Hits	1805	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

JIP3_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.040320 (rank : 125)
Query Neighborhood Hits	136	Target Neighborhood Hits	1039	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MYO1F_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.009003 (rank : 179)
Query Neighborhood Hits	136	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

NOL6_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.024074 (rank : 155)
Query Neighborhood Hits	136	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H6R4, Q5T5M3, Q5T5M4, Q7L4G6, Q8N6I0, Q8TEY9, Q8TEZ0, Q8TEZ1, Q9H675	Gene names	NOL6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

PKHA5_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.018908 (rank : 164)
Query Neighborhood Hits	136	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RPGR_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.015114 (rank : 169)
Query Neighborhood Hits	136	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

SDS3_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.036989 (rank : 135)
Query Neighborhood Hits	136	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

TBX3_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.006018 (rank : 184)
Query Neighborhood Hits	136	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

UBP47_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.012828 (rank : 173)
Query Neighborhood Hits	136	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

CCD41_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.046497 (rank : 118)
Query Neighborhood Hits	136	Target Neighborhood Hits	1399	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CUTL1_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.030787 (rank : 144)
Query Neighborhood Hits	136	Target Neighborhood Hits	1620	Shared Neighborhood Hits	60
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ERCC4_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.023216 (rank : 157)
Query Neighborhood Hits	136	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q92889, O00140, Q8TD83	Gene names	ERCC4, ERCC11, XPF
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA-repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein).

ERCC4_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.020735 (rank : 162)
Query Neighborhood Hits	136	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

HOME3_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.022975 (rank : 158)
Query Neighborhood Hits	136	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

K2C8_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.012214 (rank : 174)
Query Neighborhood Hits	136	Target Neighborhood Hits	593	Shared Neighborhood Hits	36
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

KIF5A_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.021000 (rank : 161)
Query Neighborhood Hits	136	Target Neighborhood Hits	859	Shared Neighborhood Hits	43
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

MPP3_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.005869 (rank : 185)
Query Neighborhood Hits	136	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

P85B_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.015117 (rank : 168)
Query Neighborhood Hits	136	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.015579 (rank : 167)
Query Neighborhood Hits	136	Target Neighborhood Hits	519	Shared Neighborhood Hits	23
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

REST_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.039025 (rank : 129)
Query Neighborhood Hits	136	Target Neighborhood Hits	1605	Shared Neighborhood Hits	56
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RRFM_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.030497 (rank : 145)
Query Neighborhood Hits	136	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D6S7	Gene names	Mrrf
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

SMRC1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.024094 (rank : 154)
Query Neighborhood Hits	136	Target Neighborhood Hits	375	Shared Neighborhood Hits	18
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

CLH2_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.011267 (rank : 176)
Query Neighborhood Hits	136	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).

DNMT2_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.018006 (rank : 165)
Query Neighborhood Hits	136	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

EDD1_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.006745 (rank : 182)
Query Neighborhood Hits	136	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

GOGA3_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.039589 (rank : 127)
Query Neighborhood Hits	136	Target Neighborhood Hits	1317	Shared Neighborhood Hits	50
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

KMHN1_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.033400 (rank : 139)
Query Neighborhood Hits	136	Target Neighborhood Hits	949	Shared Neighborhood Hits	50
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MOR2A_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.013545 (rank : 172)
Query Neighborhood Hits	136	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

NC6IP_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.014124 (rank : 170)
Query Neighborhood Hits	136	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

RFC1_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.029923 (rank : 146)
Query Neighborhood Hits	136	Target Neighborhood Hits	352	Shared Neighborhood Hits	21
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RRFM_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.026086 (rank : 152)
Query Neighborhood Hits	136	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q96E11, Q5RKT1, Q5T7T0, Q5T7T1, Q5T7T2, Q5T7T3, Q5T7T4, Q5T7T5	Gene names	MRRF
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

RYR2_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.006222 (rank : 183)
Query Neighborhood Hits	136	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

UBP47_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.010425 (rank : 177)
Query Neighborhood Hits	136	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

VPS72_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.043238 (rank : 120)
Query Neighborhood Hits	136	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ZBT10_HUMAN
θ value	8.99809 (rank : 134)	NC score	-0.002409 (rank : 190)
Query Neighborhood Hits	136	Target Neighborhood Hits	831	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

ZFYV1_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.013979 (rank : 171)
Query Neighborhood Hits	136	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.012065 (rank : 175)
Query Neighborhood Hits	136	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

AF10_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.058088 (rank : 102)
Query Neighborhood Hits	136	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.060013 (rank : 96)
Query Neighborhood Hits	136	Target Neighborhood Hits	182	Shared Neighborhood Hits	15
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.066314 (rank : 93)
Query Neighborhood Hits	136	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AIRE_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.141347 (rank : 50)
Query Neighborhood Hits	136	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.138152 (rank : 51)
Query Neighborhood Hits	136	Target Neighborhood Hits	196	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ATRX_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.054510 (rank : 108)
Query Neighborhood Hits	136	Target Neighborhood Hits	842	Shared Neighborhood Hits	59
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CHD3_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.078815 (rank : 73)
Query Neighborhood Hits	136	Target Neighborhood Hits	397	Shared Neighborhood Hits	32
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.077874 (rank : 77)
Query Neighborhood Hits	136	Target Neighborhood Hits	365	Shared Neighborhood Hits	32
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.077916 (rank : 76)
Query Neighborhood Hits	136	Target Neighborhood Hits	408	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.078754 (rank : 74)
Query Neighborhood Hits	136	Target Neighborhood Hits	349	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

DPF1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.072771 (rank : 85)
Query Neighborhood Hits	136	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.077630 (rank : 78)
Query Neighborhood Hits	136	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

JAD1A_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.066389 (rank : 92)
Query Neighborhood Hits	136	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1C_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.055526 (rank : 104)
Query Neighborhood Hits	136	Target Neighborhood Hits	187	Shared Neighborhood Hits	24
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.055103 (rank : 106)
Query Neighborhood Hits	136	Target Neighborhood Hits	164	Shared Neighborhood Hits	23
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.062457 (rank : 94)
Query Neighborhood Hits	136	Target Neighborhood Hits	147	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.058638 (rank : 100)
Query Neighborhood Hits	136	Target Neighborhood Hits	228	Shared Neighborhood Hits	27
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JADE1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.076686 (rank : 80)
Query Neighborhood Hits	136	Target Neighborhood Hits	140	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.076829 (rank : 79)
Query Neighborhood Hits	136	Target Neighborhood Hits	160	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.074800 (rank : 82)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.074524 (rank : 83)
Query Neighborhood Hits	136	Target Neighborhood Hits	560	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.078197 (rank : 75)
Query Neighborhood Hits	136	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.080859 (rank : 72)
Query Neighborhood Hits	136	Target Neighborhood Hits	174	Shared Neighborhood Hits	19
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

MLL2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.071617 (rank : 87)
Query Neighborhood Hits	136	Target Neighborhood Hits	1788	Shared Neighborhood Hits	55
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.072822 (rank : 84)
Query Neighborhood Hits	136	Target Neighborhood Hits	1644	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.071217 (rank : 88)
Query Neighborhood Hits	136	Target Neighborhood Hits	1399	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYST3_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.084626 (rank : 68)
Query Neighborhood Hits	136	Target Neighborhood Hits	772	Shared Neighborhood Hits	51
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.081266 (rank : 71)
Query Neighborhood Hits	136	Target Neighborhood Hits	688	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.072467 (rank : 86)
Query Neighborhood Hits	136	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.075409 (rank : 81)
Query Neighborhood Hits	136	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.126300 (rank : 56)
Query Neighborhood Hits	136	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.132666 (rank : 54)
Query Neighborhood Hits	136	Target Neighborhood Hits	285	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.100355 (rank : 59)
Query Neighborhood Hits	136	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.091938 (rank : 62)
Query Neighborhood Hits	136	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.087804 (rank : 64)
Query Neighborhood Hits	136	Target Neighborhood Hits	151	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.086519 (rank : 65)
Query Neighborhood Hits	136	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF12_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.106977 (rank : 57)
Query Neighborhood Hits	136	Target Neighborhood Hits	174	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.106779 (rank : 58)
Query Neighborhood Hits	136	Target Neighborhood Hits	172	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF14_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.085400 (rank : 67)
Query Neighborhood Hits	136	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.083836 (rank : 70)
Query Neighborhood Hits	136	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.052952 (rank : 109)
Query Neighborhood Hits	136	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.052503 (rank : 110)
Query Neighborhood Hits	136	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

REQU_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.086338 (rank : 66)
Query Neighborhood Hits	136	Target Neighborhood Hits	523	Shared Neighborhood Hits	26
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.084130 (rank : 69)
Query Neighborhood Hits	136	Target Neighborhood Hits	519	Shared Neighborhood Hits	25
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.130254 (rank : 55)
Query Neighborhood Hits	136	Target Neighborhood Hits	539	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.089743 (rank : 63)
Query Neighborhood Hits	136	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TIF1B_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.135028 (rank : 52)
Query Neighborhood Hits	136	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.133167 (rank : 53)
Query Neighborhood Hits	136	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI45_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.060218 (rank : 95)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.059433 (rank : 98)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

UHRF1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.066994 (rank : 91)
Query Neighborhood Hits	136	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.069996 (rank : 89)
Query Neighborhood Hits	136	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.058558 (rank : 101)
Query Neighborhood Hits	136	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.058983 (rank : 99)
Query Neighborhood Hits	136	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

Hits sorted by NC score

TAF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	136	Target Neighborhood Hits	136	Shared Neighborhood Hits	136
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TAF1L_HUMAN
NC score	0.985583 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	136	Target Neighborhood Hits	144	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

PCAF_HUMAN
NC score	0.597178 (rank : 3)	θ value	6.64225e-11 (rank : 8)
Query Neighborhood Hits	136	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

GCNL2_HUMAN
NC score	0.584216 (rank : 4)	θ value	4.16044e-13 (rank : 4)
Query Neighborhood Hits	136	Target Neighborhood Hits	159	Shared Neighborhood Hits	47
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
NC score	0.581118 (rank : 5)	θ value	7.09661e-13 (rank : 6)
Query Neighborhood Hits	136	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

CECR2_HUMAN
NC score	0.566963 (rank : 6)	θ value	1.68911e-14 (rank : 3)
Query Neighborhood Hits	136	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BRD2_HUMAN
NC score	0.566557 (rank : 7)	θ value	8.11959e-09 (rank : 21)
Query Neighborhood Hits	136	Target Neighborhood Hits	242	Shared Neighborhood Hits	56
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
NC score	0.563868 (rank : 8)	θ value	1.133e-10 (rank : 10)
Query Neighborhood Hits	136	Target Neighborhood Hits	369	Shared Neighborhood Hits	68
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
NC score	0.559604 (rank : 9)	θ value	1.133e-10 (rank : 11)
Query Neighborhood Hits	136	Target Neighborhood Hits	402	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRDT_HUMAN
NC score	0.555661 (rank : 10)	θ value	2.52405e-10 (rank : 12)
Query Neighborhood Hits	136	Target Neighborhood Hits	280	Shared Neighborhood Hits	70
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
NC score	0.547300 (rank : 11)	θ value	6.21693e-09 (rank : 19)
Query Neighborhood Hits	136	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

PB1_HUMAN
NC score	0.547220 (rank : 12)	θ value	4.16044e-13 (rank : 5)
Query Neighborhood Hits	136	Target Neighborhood Hits	261	Shared Neighborhood Hits	49
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

BRD7_HUMAN
NC score	0.535102 (rank : 13)	θ value	2.36244e-08 (rank : 24)
Query Neighborhood Hits	136	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
NC score	0.527994 (rank : 14)	θ value	1.80886e-08 (rank : 23)
Query Neighborhood Hits	136	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD9_HUMAN
NC score	0.525218 (rank : 15)	θ value	5.81887e-07 (rank : 33)
Query Neighborhood Hits	136	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
NC score	0.523453 (rank : 16)	θ value	9.92553e-07 (rank : 38)
Query Neighborhood Hits	136	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD4_HUMAN
NC score	0.503623 (rank : 17)	θ value	4.76016e-09 (rank : 17)
Query Neighborhood Hits	136	Target Neighborhood Hits	851	Shared Neighborhood Hits	73
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
NC score	0.500925 (rank : 18)	θ value	4.76016e-09 (rank : 18)
Query Neighborhood Hits	136	Target Neighborhood Hits	845	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD8_HUMAN
NC score	0.497396 (rank : 19)	θ value	7.59969e-07 (rank : 36)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BAZ1A_HUMAN
NC score	0.474974 (rank : 20)	θ value	2.13673e-09 (rank : 13)
Query Neighborhood Hits	136	Target Neighborhood Hits	693	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ2B_HUMAN
NC score	0.467406 (rank : 21)	θ value	8.67504e-11 (rank : 9)
Query Neighborhood Hits	136	Target Neighborhood Hits	803	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD8_MOUSE
NC score	0.462448 (rank : 22)	θ value	6.43352e-06 (rank : 40)
Query Neighborhood Hits	136	Target Neighborhood Hits	422	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BAZ1B_MOUSE
NC score	0.461027 (rank : 23)	θ value	1.38499e-08 (rank : 22)
Query Neighborhood Hits	136	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BPTF_HUMAN
NC score	0.454596 (rank : 24)	θ value	3.64472e-09 (rank : 16)
Query Neighborhood Hits	136	Target Neighborhood Hits	786	Shared Neighborhood Hits	71
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BAZ2A_HUMAN
NC score	0.452369 (rank : 25)	θ value	5.26297e-08 (rank : 29)
Query Neighborhood Hits	136	Target Neighborhood Hits	780	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PKCB1_HUMAN
NC score	0.449113 (rank : 26)	θ value	2.28291e-11 (rank : 7)
Query Neighborhood Hits	136	Target Neighborhood Hits	488	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BAZ2A_MOUSE
NC score	0.444849 (rank : 27)	θ value	4.0297e-08 (rank : 27)
Query Neighborhood Hits	136	Target Neighborhood Hits	744	Shared Neighborhood Hits	70
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CBP_HUMAN
NC score	0.427829 (rank : 28)	θ value	6.21693e-09 (rank : 20)
Query Neighborhood Hits	136	Target Neighborhood Hits	941	Shared Neighborhood Hits	56
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EP300_HUMAN
NC score	0.425684 (rank : 29)	θ value	5.26297e-08 (rank : 30)
Query Neighborhood Hits	136	Target Neighborhood Hits	821	Shared Neighborhood Hits	56
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

BAZ1B_HUMAN
NC score	0.425578 (rank : 30)	θ value	4.0297e-08 (rank : 26)
Query Neighborhood Hits	136	Target Neighborhood Hits	701	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CBP_MOUSE
NC score	0.415551 (rank : 31)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	136	Target Neighborhood Hits	1051	Shared Neighborhood Hits	59
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TIF1A_MOUSE
NC score	0.408618 (rank : 32)	θ value	3.41135e-07 (rank : 32)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	53
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.404111 (rank : 33)	θ value	1.99992e-07 (rank : 31)
Query Neighborhood Hits	136	Target Neighborhood Hits	327	Shared Neighborhood Hits	56
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

BRPF3_HUMAN
NC score	0.399627 (rank : 34)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	136	Target Neighborhood Hits	217	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

TRI66_HUMAN
NC score	0.381435 (rank : 35)	θ value	1.09739e-05 (rank : 42)
Query Neighborhood Hits	136	Target Neighborhood Hits	479	Shared Neighborhood Hits	59
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
NC score	0.379542 (rank : 36)	θ value	8.40245e-06 (rank : 41)
Query Neighborhood Hits	136	Target Neighborhood Hits	491	Shared Neighborhood Hits	61
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BRD1_HUMAN
NC score	0.374093 (rank : 37)	θ value	7.59969e-07 (rank : 35)
Query Neighborhood Hits	136	Target Neighborhood Hits	188	Shared Neighborhood Hits	49
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
NC score	0.355745 (rank : 38)	θ value	7.59969e-07 (rank : 37)
Query Neighborhood Hits	136	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

TIF1G_HUMAN
NC score	0.340487 (rank : 39)	θ value	3.19293e-05 (rank : 43)
Query Neighborhood Hits	136	Target Neighborhood Hits	410	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.335193 (rank : 40)	θ value	4.1701e-05 (rank : 44)
Query Neighborhood Hits	136	Target Neighborhood Hits	498	Shared Neighborhood Hits	56
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

BRWD1_HUMAN
NC score	0.288989 (rank : 41)	θ value	2.36244e-08 (rank : 25)
Query Neighborhood Hits	136	Target Neighborhood Hits	448	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_MOUSE
NC score	0.278703 (rank : 42)	θ value	9.92553e-07 (rank : 39)
Query Neighborhood Hits	136	Target Neighborhood Hits	478	Shared Neighborhood Hits	51
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

ZMY11_MOUSE
NC score	0.278396 (rank : 43)	θ value	0.00298849 (rank : 48)
Query Neighborhood Hits	136	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.278356 (rank : 44)	θ value	0.00298849 (rank : 47)
Query Neighborhood Hits	136	Target Neighborhood Hits	201	Shared Neighborhood Hits	43
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ATAD2_HUMAN
NC score	0.259459 (rank : 45)	θ value	5.26297e-08 (rank : 28)
Query Neighborhood Hits	136	Target Neighborhood Hits	322	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
NC score	0.257247 (rank : 46)	θ value	7.59969e-07 (rank : 34)
Query Neighborhood Hits	136	Target Neighborhood Hits	167	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

LY10_HUMAN
NC score	0.202731 (rank : 47)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	136	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SMCA2_HUMAN
NC score	0.183527 (rank : 48)	θ value	0.00102713 (rank : 46)
Query Neighborhood Hits	136	Target Neighborhood Hits	503	Shared Neighborhood Hits	63
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.183175 (rank : 49)	θ value	0.000786445 (rank : 45)
Query Neighborhood Hits	136	Target Neighborhood Hits	597	Shared Neighborhood Hits	67
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

AIRE_HUMAN
NC score	0.141347 (rank : 50)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	136	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.138152 (rank : 51)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	136	Target Neighborhood Hits	196	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TIF1B_HUMAN
NC score	0.135028 (rank : 52)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	136	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.133167 (rank : 53)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	136	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

PF21A_MOUSE
NC score	0.132666 (rank : 54)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	136	Target Neighborhood Hits	285	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

RSF1_HUMAN
NC score	0.130254 (rank : 55)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	136	Target Neighborhood Hits	539	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PF21A_HUMAN
NC score	0.126300 (rank : 56)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	136	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PHF12_HUMAN
NC score	0.106977 (rank : 57)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	136	Target Neighborhood Hits	174	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.106779 (rank : 58)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	136	Target Neighborhood Hits	172	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21B_HUMAN
NC score	0.100355 (rank : 59)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	136	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MYST4_HUMAN
NC score	0.098756 (rank : 60)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	136	Target Neighborhood Hits	671	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
NC score	0.092631 (rank : 61)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	136	Target Neighborhood Hits	416	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PF21B_MOUSE
NC score	0.091938 (rank : 62)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	136	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SP110_HUMAN
NC score	0.089743 (rank : 63)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	136	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

PHF10_HUMAN
NC score	0.087804 (rank : 64)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	136	Target Neighborhood Hits	151	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.086519 (rank : 65)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	136	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

REQU_HUMAN
NC score	0.086338 (rank : 66)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	136	Target Neighborhood Hits	523	Shared Neighborhood Hits	26
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PHF14_HUMAN
NC score	0.085400 (rank : 67)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	136	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

MYST3_HUMAN
NC score	0.084626 (rank : 68)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	136	Target Neighborhood Hits	772	Shared Neighborhood Hits	51
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

REQU_MOUSE
NC score	0.084130 (rank : 69)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	136	Target Neighborhood Hits	519	Shared Neighborhood Hits	25
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PHF14_MOUSE
NC score	0.083836 (rank : 70)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	136	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

MYST3_MOUSE
NC score	0.081266 (rank : 71)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	136	Target Neighborhood Hits	688	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

JADE3_MOUSE
NC score	0.080859 (rank : 72)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	136	Target Neighborhood Hits	174	Shared Neighborhood Hits	19
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

CHD3_HUMAN
NC score	0.078815 (rank : 73)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	136	Target Neighborhood Hits	397	Shared Neighborhood Hits	32
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
NC score	0.078754 (rank : 74)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	136	Target Neighborhood Hits	349	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

JADE3_HUMAN
NC score	0.078197 (rank : 75)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	136	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

CHD4_MOUSE
NC score	0.077916 (rank : 76)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	136	Target Neighborhood Hits	408	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.077874 (rank : 77)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	136	Target Neighborhood Hits	365	Shared Neighborhood Hits	32
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

DPF1_MOUSE
NC score	0.077630 (rank : 78)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	136	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

JADE1_MOUSE
NC score	0.076829 (rank : 79)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	136	Target Neighborhood Hits	160	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_HUMAN
NC score	0.076686 (rank : 80)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	136	Target Neighborhood Hits	140	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

NSD1_MOUSE
NC score	0.075409 (rank : 81)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	136	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

JADE2_HUMAN
NC score	0.074800 (rank : 82)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
NC score	0.074524 (rank : 83)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	136	Target Neighborhood Hits	560	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MLL3_HUMAN
NC score	0.072822 (rank : 84)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	136	Target Neighborhood Hits	1644	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DPF1_HUMAN
NC score	0.072771 (rank : 85)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	136	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

NSD1_HUMAN
NC score	0.072467 (rank : 86)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	136	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MLL2_HUMAN
NC score	0.071617 (rank : 87)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	136	Target Neighborhood Hits	1788	Shared Neighborhood Hits	55
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
NC score	0.071217 (rank : 88)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	136	Target Neighborhood Hits	1399	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

UHRF1_MOUSE
NC score	0.069996 (rank : 89)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	136	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

XRCC4_HUMAN
NC score	0.069607 (rank : 90)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	136	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

UHRF1_HUMAN
NC score	0.066994 (rank : 91)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	136	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

JAD1A_HUMAN
NC score	0.066389 (rank : 92)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	136	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

AF17_HUMAN
NC score	0.066314 (rank : 93)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	136	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

JAD1D_HUMAN
NC score	0.062457 (rank : 94)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	136	Target Neighborhood Hits	147	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

TRI45_HUMAN
NC score	0.060218 (rank : 95)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

AF10_MOUSE
NC score	0.060013 (rank : 96)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	136	Target Neighborhood Hits	182	Shared Neighborhood Hits	15
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

LEO1_MOUSE
NC score	0.059557 (rank : 97)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	136	Target Neighborhood Hits	946	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TRI45_MOUSE
NC score	0.059433 (rank : 98)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

UHRF2_MOUSE
NC score	0.058983 (rank : 99)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	136	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

JAD1D_MOUSE
NC score	0.058638 (rank : 100)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	136	Target Neighborhood Hits	228	Shared Neighborhood Hits	27
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

UHRF2_HUMAN
NC score	0.058558 (rank : 101)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	136	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

AF10_HUMAN
NC score	0.058088 (rank : 102)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	136	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

ACINU_HUMAN
NC score	0.056897 (rank : 103)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	136	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

JAD1C_HUMAN
NC score	0.055526 (rank : 104)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	136	Target Neighborhood Hits	187	Shared Neighborhood Hits	24
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

LEO1_HUMAN
NC score	0.055469 (rank : 105)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	136	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

JAD1C_MOUSE
NC score	0.055103 (rank : 106)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	136	Target Neighborhood Hits	164	Shared Neighborhood Hits	23
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

CEP72_MOUSE
NC score	0.054886 (rank : 107)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	136	Target Neighborhood Hits	381	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

ATRX_HUMAN
NC score	0.054510 (rank : 108)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	136	Target Neighborhood Hits	842	Shared Neighborhood Hits	59
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

PHF1_HUMAN
NC score	0.052952 (rank : 109)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	136	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.052503 (rank : 110)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	136	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

CCD41_HUMAN
NC score	0.052469 (rank : 111)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	136	Target Neighborhood Hits	1139	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

ZCHC6_HUMAN
NC score	0.051039 (rank : 112)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	136	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

GCC2_MOUSE
NC score	0.050743 (rank : 113)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	136	Target Neighborhood Hits	1619	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RBP24_HUMAN
NC score	0.049174 (rank : 114)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	136	Target Neighborhood Hits	1559	Shared Neighborhood Hits	55
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.049092 (rank : 115)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	136	Target Neighborhood Hits	1558	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MY18A_MOUSE
NC score	0.047900 (rank : 116)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	136	Target Neighborhood Hits	1989	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_HUMAN
NC score	0.047001 (rank : 117)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	136	Target Neighborhood Hits	1929	Shared Neighborhood Hits	73
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD41_MOUSE
NC score	0.046497 (rank : 118)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	136	Target Neighborhood Hits	1399	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

PPCT_MOUSE
NC score	0.045565 (rank : 119)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	136	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P53808, Q9QZX0, Q9R058	Gene names	Pctp, Stard2
Domain Architecture
Description	Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2).

VPS72_MOUSE
NC score	0.043238 (rank : 120)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	136	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CCD46_HUMAN
NC score	0.042603 (rank : 121)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	136	Target Neighborhood Hits	1430	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TMF1_HUMAN
NC score	0.042594 (rank : 122)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	136	Target Neighborhood Hits	987	Shared Neighborhood Hits	47
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

IFT74_HUMAN
NC score	0.042543 (rank : 123)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	136	Target Neighborhood Hits	949	Shared Neighborhood Hits	44
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ZCHC6_MOUSE
NC score	0.042466 (rank : 124)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	136	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

JIP3_HUMAN
NC score	0.040320 (rank : 125)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	136	Target Neighborhood Hits	1039	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

FLIP1_HUMAN
NC score	0.039997 (rank : 126)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	136	Target Neighborhood Hits	1405	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA3_HUMAN
NC score	0.039589 (rank : 127)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	136	Target Neighborhood Hits	1317	Shared Neighborhood Hits	50
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
NC score	0.039536 (rank : 128)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	136	Target Neighborhood Hits	1437	Shared Neighborhood Hits	59
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

REST_HUMAN
NC score	0.039025 (rank : 129)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	136	Target Neighborhood Hits	1605	Shared Neighborhood Hits	56
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TNIP3_HUMAN
NC score	0.038217 (rank : 130)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	136	Target Neighborhood Hits	511	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

K0831_MOUSE
NC score	0.038143 (rank : 131)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	136	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MD1L1_HUMAN
NC score	0.038084 (rank : 132)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	136	Target Neighborhood Hits	893	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CP250_HUMAN
NC score	0.037373 (rank : 133)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	136	Target Neighborhood Hits	1805	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

TEX2_HUMAN
NC score	0.037026 (rank : 134)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	136	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

SDS3_MOUSE
NC score	0.036989 (rank : 135)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	136	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

LIPA2_MOUSE
NC score	0.035853 (rank : 136)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	136	Target Neighborhood Hits	1282	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

UACA_MOUSE
NC score	0.035434 (rank : 137)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	136	Target Neighborhood Hits	1620	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GAS8_HUMAN
NC score	0.034529 (rank : 138)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	136	Target Neighborhood Hits	819	Shared Neighborhood Hits	40
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

KMHN1_MOUSE
NC score	0.033400 (rank : 139)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	136	Target Neighborhood Hits	949	Shared Neighborhood Hits	50
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

BPA1_MOUSE
NC score	0.032233 (rank : 140)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	136	Target Neighborhood Hits	1477	Shared Neighborhood Hits	60
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BICD1_MOUSE
NC score	0.031507 (rank : 141)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	136	Target Neighborhood Hits	837	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

SYNE2_HUMAN
NC score	0.031281 (rank : 142)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	136	Target Neighborhood Hits	1323	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

JIP3_MOUSE
NC score	0.031218 (rank : 143)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	136	Target Neighborhood Hits	759	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

CUTL1_MOUSE
NC score	0.030787 (rank : 144)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	136	Target Neighborhood Hits	1620	Shared Neighborhood Hits	60
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RRFM_MOUSE
NC score	0.030497 (rank : 145)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	136	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D6S7	Gene names	Mrrf
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

RFC1_HUMAN
NC score	0.029923 (rank : 146)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	136	Target Neighborhood Hits	352	Shared Neighborhood Hits	21
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

OGFR_MOUSE
NC score	0.029394 (rank : 147)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	136	Target Neighborhood Hits	584	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

WDHD1_HUMAN
NC score	0.027769 (rank : 148)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	136	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

ZN638_MOUSE
NC score	0.027264 (rank : 149)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	136	Target Neighborhood Hits	318	Shared Neighborhood Hits	20
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

SPTA2_HUMAN
NC score	0.027050 (rank : 150)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	136	Target Neighborhood Hits	888	Shared Neighborhood Hits	33
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

UBP13_HUMAN
NC score	0.026265 (rank : 151)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	136	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

RRFM_HUMAN
NC score	0.026086 (rank : 152)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	136	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q96E11, Q5RKT1, Q5T7T0, Q5T7T1, Q5T7T2, Q5T7T3, Q5T7T4, Q5T7T5	Gene names	MRRF
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

STK10_MOUSE
NC score	0.025402 (rank : 153)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	136	Target Neighborhood Hits	2132	Shared Neighborhood Hits	65
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SMRC1_HUMAN
NC score	0.024094 (rank : 154)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	136	Target Neighborhood Hits	375	Shared Neighborhood Hits	18
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

NOL6_HUMAN
NC score	0.024074 (rank : 155)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	136	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H6R4, Q5T5M3, Q5T5M4, Q7L4G6, Q8N6I0, Q8TEY9, Q8TEZ0, Q8TEZ1, Q9H675	Gene names	NOL6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

WRN_HUMAN
NC score	0.023699 (rank : 156)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	136	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

ERCC4_HUMAN
NC score	0.023216 (rank : 157)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	136	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q92889, O00140, Q8TD83	Gene names	ERCC4, ERCC11, XPF
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA-repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein).

HOME3_HUMAN
NC score	0.022975 (rank : 158)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	136	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

MRCKB_HUMAN
NC score	0.022311 (rank : 159)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	136	Target Neighborhood Hits	2239	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PVRL2_MOUSE
NC score	0.021735 (rank : 160)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	136	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

KIF5A_MOUSE
NC score	0.021000 (rank : 161)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	136	Target Neighborhood Hits	859	Shared Neighborhood Hits	43
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

ERCC4_MOUSE
NC score	0.020735 (rank : 162)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	136	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

STX1B_HUMAN
NC score	0.019235 (rank : 163)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	136	Target Neighborhood Hits	252	Shared Neighborhood Hits	22
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

PKHA5_HUMAN
NC score	0.018908 (rank : 164)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	136	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

DNMT2_HUMAN
NC score	0.018006 (rank : 165)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	136	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

STK10_HUMAN
NC score	0.017651 (rank : 166)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	136	Target Neighborhood Hits	1921	Shared Neighborhood Hits	59
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

P85B_MOUSE
NC score	0.015579 (rank : 167)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	136	Target Neighborhood Hits	519	Shared Neighborhood Hits	23
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_HUMAN
NC score	0.015117 (rank : 168)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	136	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RPGR_MOUSE
NC score	0.015114 (rank : 169)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	136	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

NC6IP_HUMAN
NC score	0.014124 (rank : 170)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	136	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

ZFYV1_HUMAN
NC score	0.013979 (rank : 171)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	136	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

MOR2A_MOUSE
NC score	0.013545 (rank : 172)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	136	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

UBP47_HUMAN
NC score	0.012828 (rank : 173)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	136	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

K2C8_HUMAN
NC score	0.012214 (rank : 174)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	136	Target Neighborhood Hits	593	Shared Neighborhood Hits	36
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

ZFYV1_MOUSE
NC score	0.012065 (rank : 175)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	136	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

CLH2_HUMAN
NC score	0.011267 (rank : 176)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	136	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).

UBP47_MOUSE
NC score	0.010425 (rank : 177)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	136	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

GRIP1_MOUSE
NC score	0.009354 (rank : 178)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	136	Target Neighborhood Hits	241	Shared Neighborhood Hits	6
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MYO1F_HUMAN
NC score	0.009003 (rank : 179)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	136	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SUHW4_MOUSE
NC score	0.007522 (rank : 180)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	136	Target Neighborhood Hits	737	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ABCAD_HUMAN
NC score	0.007003 (rank : 181)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	136	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

EDD1_HUMAN
NC score	0.006745 (rank : 182)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	136	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

RYR2_HUMAN
NC score	0.006222 (rank : 183)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	136	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

TBX3_HUMAN
NC score	0.006018 (rank : 184)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	136	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

MPP3_HUMAN
NC score	0.005869 (rank : 185)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	136	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

RASK_MOUSE
NC score	0.005835 (rank : 186)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	136	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	P32883, P04200, P08643	Gene names	Kras, Kras2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

HS70L_HUMAN
NC score	0.005336 (rank : 187)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	136	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

RASK_HUMAN
NC score	0.005154 (rank : 188)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	136	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	P01116, P01118, Q96D10	Gene names	KRAS, KRAS2, RASK2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

LAP4_MOUSE
NC score	0.003019 (rank : 189)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	136	Target Neighborhood Hits	590	Shared Neighborhood Hits	8
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

ZBT10_HUMAN
NC score	-0.002409 (rank : 190)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	136	Target Neighborhood Hits	831	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).