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Network neighborhood for query Sequence : LY10_HUMAN

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LY10_HUMAN
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LY10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	151
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SP100_HUMAN
θ value	1.14825e-79 (rank : 2)	NC score	0.494843 (rank : 14)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SP110_HUMAN
θ value	2.3998e-69 (rank : 3)	NC score	0.874152 (rank : 2)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

IPR1_MOUSE
θ value	1.86321e-21 (rank : 4)	NC score	0.616979 (rank : 3)
Query Neighborhood Hits	151	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

TIF1A_MOUSE
θ value	3.17815e-21 (rank : 5)	NC score	0.567728 (rank : 10)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	86
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

SP100_MOUSE
θ value	5.42112e-21 (rank : 6)	NC score	0.578708 (rank : 6)
Query Neighborhood Hits	151	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

TIF1A_HUMAN
θ value	9.24701e-21 (rank : 7)	NC score	0.559089 (rank : 11)
Query Neighborhood Hits	151	Target Neighborhood Hits	327	Shared Neighborhood Hits	86
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1G_HUMAN
θ value	4.58923e-20 (rank : 8)	NC score	0.531835 (rank : 12)
Query Neighborhood Hits	151	Target Neighborhood Hits	410	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	1.02238e-19 (rank : 9)	NC score	0.529545 (rank : 13)
Query Neighborhood Hits	151	Target Neighborhood Hits	498	Shared Neighborhood Hits	86
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

S100R_MOUSE
θ value	9.56915e-18 (rank : 10)	NC score	0.576386 (rank : 7)
Query Neighborhood Hits	151	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

TRI66_HUMAN
θ value	4.74913e-17 (rank : 11)	NC score	0.571145 (rank : 8)
Query Neighborhood Hits	151	Target Neighborhood Hits	479	Shared Neighborhood Hits	88
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	1.80466e-16 (rank : 12)	NC score	0.570793 (rank : 9)
Query Neighborhood Hits	151	Target Neighborhood Hits	491	Shared Neighborhood Hits	89
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

AIRE_HUMAN
θ value	1.2105e-12 (rank : 13)	NC score	0.595718 (rank : 4)
Query Neighborhood Hits	151	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	1.2105e-12 (rank : 14)	NC score	0.595451 (rank : 5)
Query Neighborhood Hits	151	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

DEAF1_HUMAN
θ value	2.52405e-10 (rank : 15)	NC score	0.373945 (rank : 24)
Query Neighborhood Hits	151	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
θ value	2.52405e-10 (rank : 16)	NC score	0.373628 (rank : 25)
Query Neighborhood Hits	151	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

TIF1B_HUMAN
θ value	5.62301e-10 (rank : 17)	NC score	0.470911 (rank : 16)
Query Neighborhood Hits	151	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	1.25267e-09 (rank : 18)	NC score	0.472979 (rank : 15)
Query Neighborhood Hits	151	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

BPTF_HUMAN
θ value	6.87365e-08 (rank : 19)	NC score	0.393232 (rank : 23)
Query Neighborhood Hits	151	Target Neighborhood Hits	786	Shared Neighborhood Hits	91
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PHF12_HUMAN
θ value	4.45536e-07 (rank : 20)	NC score	0.459217 (rank : 19)
Query Neighborhood Hits	151	Target Neighborhood Hits	174	Shared Neighborhood Hits	67
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	4.45536e-07 (rank : 21)	NC score	0.459351 (rank : 18)
Query Neighborhood Hits	151	Target Neighborhood Hits	172	Shared Neighborhood Hits	68
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CHD4_HUMAN
θ value	2.21117e-06 (rank : 22)	NC score	0.278619 (rank : 38)
Query Neighborhood Hits	151	Target Neighborhood Hits	365	Shared Neighborhood Hits	76
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	2.21117e-06 (rank : 23)	NC score	0.277074 (rank : 39)
Query Neighborhood Hits	151	Target Neighborhood Hits	408	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

PF21A_HUMAN
θ value	2.88788e-06 (rank : 24)	NC score	0.454477 (rank : 20)
Query Neighborhood Hits	151	Target Neighborhood Hits	303	Shared Neighborhood Hits	73
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	2.88788e-06 (rank : 25)	NC score	0.462262 (rank : 17)
Query Neighborhood Hits	151	Target Neighborhood Hits	285	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CHD3_HUMAN
θ value	4.92598e-06 (rank : 26)	NC score	0.272414 (rank : 40)
Query Neighborhood Hits	151	Target Neighborhood Hits	397	Shared Neighborhood Hits	74
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
θ value	4.92598e-06 (rank : 27)	NC score	0.281556 (rank : 37)
Query Neighborhood Hits	151	Target Neighborhood Hits	349	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

GMEB1_HUMAN
θ value	3.19293e-05 (rank : 28)	NC score	0.261003 (rank : 41)
Query Neighborhood Hits	151	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

GMEB1_MOUSE
θ value	4.1701e-05 (rank : 29)	NC score	0.260166 (rank : 42)
Query Neighborhood Hits	151	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

NSD1_HUMAN
θ value	0.000158464 (rank : 30)	NC score	0.300037 (rank : 33)
Query Neighborhood Hits	151	Target Neighborhood Hits	427	Shared Neighborhood Hits	71
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0.000158464 (rank : 31)	NC score	0.302665 (rank : 32)
Query Neighborhood Hits	151	Target Neighborhood Hits	472	Shared Neighborhood Hits	73
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

GMEB2_HUMAN
θ value	0.00020696 (rank : 32)	NC score	0.252680 (rank : 44)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
θ value	0.00020696 (rank : 33)	NC score	0.252916 (rank : 43)
Query Neighborhood Hits	151	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

PKCB1_HUMAN
θ value	0.000602161 (rank : 34)	NC score	0.409906 (rank : 21)
Query Neighborhood Hits	151	Target Neighborhood Hits	488	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PHF1_HUMAN
θ value	0.000786445 (rank : 35)	NC score	0.227777 (rank : 53)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PF21B_HUMAN
θ value	0.00298849 (rank : 36)	NC score	0.404291 (rank : 22)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF1_MOUSE
θ value	0.00298849 (rank : 37)	NC score	0.222788 (rank : 59)
Query Neighborhood Hits	151	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

BAZ2B_HUMAN
θ value	0.00509761 (rank : 38)	NC score	0.312561 (rank : 30)
Query Neighborhood Hits	151	Target Neighborhood Hits	803	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD3_MOUSE
θ value	0.00665767 (rank : 39)	NC score	0.236283 (rank : 48)
Query Neighborhood Hits	151	Target Neighborhood Hits	402	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	0.00665767 (rank : 40)	NC score	0.222456 (rank : 60)
Query Neighborhood Hits	151	Target Neighborhood Hits	851	Shared Neighborhood Hits	52
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

SON_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.084370 (rank : 132)
Query Neighborhood Hits	151	Target Neighborhood Hits	957	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BRD3_HUMAN
θ value	0.0113563 (rank : 42)	NC score	0.236360 (rank : 47)
Query Neighborhood Hits	151	Target Neighborhood Hits	369	Shared Neighborhood Hits	42
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

SON_HUMAN
θ value	0.0113563 (rank : 43)	NC score	0.085154 (rank : 130)
Query Neighborhood Hits	151	Target Neighborhood Hits	1568	Shared Neighborhood Hits	56
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ATRX_MOUSE
θ value	0.0148317 (rank : 44)	NC score	0.156288 (rank : 99)
Query Neighborhood Hits	151	Target Neighborhood Hits	682	Shared Neighborhood Hits	54
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BRD4_MOUSE
θ value	0.0148317 (rank : 45)	NC score	0.220958 (rank : 62)
Query Neighborhood Hits	151	Target Neighborhood Hits	845	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MYST3_HUMAN
θ value	0.0148317 (rank : 46)	NC score	0.222078 (rank : 61)
Query Neighborhood Hits	151	Target Neighborhood Hits	772	Shared Neighborhood Hits	74
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.0148317 (rank : 47)	NC score	0.224690 (rank : 58)
Query Neighborhood Hits	151	Target Neighborhood Hits	688	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

ATRX_HUMAN
θ value	0.0193708 (rank : 48)	NC score	0.148296 (rank : 101)
Query Neighborhood Hits	151	Target Neighborhood Hits	842	Shared Neighborhood Hits	64
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

JAD1D_MOUSE
θ value	0.0193708 (rank : 49)	NC score	0.216017 (rank : 66)
Query Neighborhood Hits	151	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PF21B_MOUSE
θ value	0.0330416 (rank : 50)	NC score	0.370315 (rank : 26)
Query Neighborhood Hits	151	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BAZ2A_MOUSE
θ value	0.0431538 (rank : 51)	NC score	0.338794 (rank : 28)
Query Neighborhood Hits	151	Target Neighborhood Hits	744	Shared Neighborhood Hits	91
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST4_HUMAN
θ value	0.0431538 (rank : 52)	NC score	0.224857 (rank : 57)
Query Neighborhood Hits	151	Target Neighborhood Hits	671	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

BRD2_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.245765 (rank : 45)
Query Neighborhood Hits	151	Target Neighborhood Hits	242	Shared Neighborhood Hits	42
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRWD1_MOUSE
θ value	0.0563607 (rank : 54)	NC score	0.117936 (rank : 116)
Query Neighborhood Hits	151	Target Neighborhood Hits	478	Shared Neighborhood Hits	43
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

MLL2_HUMAN
θ value	0.0563607 (rank : 55)	NC score	0.202239 (rank : 73)
Query Neighborhood Hits	151	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYST4_MOUSE
θ value	0.0563607 (rank : 56)	NC score	0.233428 (rank : 49)
Query Neighborhood Hits	151	Target Neighborhood Hits	416	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

JAD1D_HUMAN
θ value	0.0736092 (rank : 57)	NC score	0.220381 (rank : 63)
Query Neighborhood Hits	151	Target Neighborhood Hits	147	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PHF22_MOUSE
θ value	0.0736092 (rank : 58)	NC score	0.217712 (rank : 64)
Query Neighborhood Hits	151	Target Neighborhood Hits	89	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ZMY11_HUMAN
θ value	0.0736092 (rank : 59)	NC score	0.295726 (rank : 35)
Query Neighborhood Hits	151	Target Neighborhood Hits	201	Shared Neighborhood Hits	68
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

BAZ2A_HUMAN
θ value	0.0961366 (rank : 60)	NC score	0.343154 (rank : 27)
Query Neighborhood Hits	151	Target Neighborhood Hits	780	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

TAF1_HUMAN
θ value	0.0961366 (rank : 61)	NC score	0.202731 (rank : 72)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	38
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

BAZ1B_HUMAN
θ value	0.125558 (rank : 62)	NC score	0.299481 (rank : 34)
Query Neighborhood Hits	151	Target Neighborhood Hits	701	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	0.125558 (rank : 63)	NC score	0.319303 (rank : 29)
Query Neighborhood Hits	151	Target Neighborhood Hits	394	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

MLL3_HUMAN
θ value	0.125558 (rank : 64)	NC score	0.193067 (rank : 78)
Query Neighborhood Hits	151	Target Neighborhood Hits	1644	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	0.125558 (rank : 65)	NC score	0.205564 (rank : 70)
Query Neighborhood Hits	151	Target Neighborhood Hits	1399	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF14_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.198036 (rank : 75)
Query Neighborhood Hits	151	Target Neighborhood Hits	447	Shared Neighborhood Hits	72
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	0.125558 (rank : 67)	NC score	0.199587 (rank : 74)
Query Neighborhood Hits	151	Target Neighborhood Hits	342	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF22_HUMAN
θ value	0.125558 (rank : 68)	NC score	0.214629 (rank : 67)
Query Neighborhood Hits	151	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SPB8_MOUSE
θ value	0.125558 (rank : 69)	NC score	0.011943 (rank : 227)
Query Neighborhood Hits	151	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	O08800	Gene names	Serpinb8
Domain Architecture	No domain graphic available
Description	Serpin B8.

CECR2_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.216177 (rank : 65)
Query Neighborhood Hits	151	Target Neighborhood Hits	543	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

XRCC4_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.050373 (rank : 205)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

BRDT_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.231631 (rank : 50)
Query Neighborhood Hits	151	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

AMPH_MOUSE
θ value	0.279714 (rank : 73)	NC score	0.032030 (rank : 212)
Query Neighborhood Hits	151	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

JAD1C_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.206304 (rank : 69)
Query Neighborhood Hits	151	Target Neighborhood Hits	187	Shared Neighborhood Hits	57
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0.279714 (rank : 75)	NC score	0.206900 (rank : 68)
Query Neighborhood Hits	151	Target Neighborhood Hits	164	Shared Neighborhood Hits	57
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

SVIL_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.028066 (rank : 213)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	9
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

CBP_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.166881 (rank : 91)
Query Neighborhood Hits	151	Target Neighborhood Hits	1051	Shared Neighborhood Hits	59
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TAF1L_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.193726 (rank : 77)
Query Neighborhood Hits	151	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

ZCPW1_MOUSE
θ value	0.365318 (rank : 79)	NC score	0.052678 (rank : 203)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

BRDT_MOUSE
θ value	0.47712 (rank : 80)	NC score	0.228937 (rank : 52)
Query Neighborhood Hits	151	Target Neighborhood Hits	243	Shared Neighborhood Hits	36
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BRWD1_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.111759 (rank : 119)
Query Neighborhood Hits	151	Target Neighborhood Hits	448	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

K1045_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.072312 (rank : 148)
Query Neighborhood Hits	151	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TL4, Q8BH08	Gene names	Kiaa1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

RTN1_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.033452 (rank : 211)
Query Neighborhood Hits	151	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

BAZ1A_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.310951 (rank : 31)
Query Neighborhood Hits	151	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

JADE2_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.145810 (rank : 102)
Query Neighborhood Hits	151	Target Neighborhood Hits	199	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.139613 (rank : 105)
Query Neighborhood Hits	151	Target Neighborhood Hits	560	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

RANB3_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.043143 (rank : 207)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

DPF1_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.227492 (rank : 54)
Query Neighborhood Hits	151	Target Neighborhood Hits	491	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DSPP_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.056100 (rank : 196)
Query Neighborhood Hits	151	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

K1045_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.062240 (rank : 177)
Query Neighborhood Hits	151	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPV7, Q58FE9, Q5T662	Gene names	KIAA1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

ZMY11_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.291012 (rank : 36)
Query Neighborhood Hits	151	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ADCY8_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.015982 (rank : 222)
Query Neighborhood Hits	151	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P40145	Gene names	ADCY8
Domain Architecture
Description	Adenylate cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type VIII) (ATP pyrophosphate-lyase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase).

IWS1_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.062165 (rank : 178)
Query Neighborhood Hits	151	Target Neighborhood Hits	1258	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UHRF1_MOUSE
θ value	1.38821 (rank : 94)	NC score	0.190139 (rank : 80)
Query Neighborhood Hits	151	Target Neighborhood Hits	278	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_MOUSE
θ value	1.38821 (rank : 95)	NC score	0.160033 (rank : 95)
Query Neighborhood Hits	151	Target Neighborhood Hits	275	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

JAD1A_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.204498 (rank : 71)
Query Neighborhood Hits	151	Target Neighborhood Hits	328	Shared Neighborhood Hits	66
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JADE1_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.142968 (rank : 103)
Query Neighborhood Hits	151	Target Neighborhood Hits	140	Shared Neighborhood Hits	58
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.142718 (rank : 104)
Query Neighborhood Hits	151	Target Neighborhood Hits	160	Shared Neighborhood Hits	58
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

NDF2_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.013772 (rank : 225)
Query Neighborhood Hits	151	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

PB1_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.177919 (rank : 86)
Query Neighborhood Hits	151	Target Neighborhood Hits	261	Shared Neighborhood Hits	40
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

SFR11_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.067659 (rank : 159)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

DLL1_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.004300 (rank : 242)
Query Neighborhood Hits	151	Target Neighborhood Hits	455	Shared Neighborhood Hits	9
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

MTF1_MOUSE
θ value	2.36792 (rank : 103)	NC score	-0.001067 (rank : 247)
Query Neighborhood Hits	151	Target Neighborhood Hits	785	Shared Neighborhood Hits	10
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MYO7A_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.010010 (rank : 234)
Query Neighborhood Hits	151	Target Neighborhood Hits	209	Shared Neighborhood Hits	5
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.009771 (rank : 235)
Query Neighborhood Hits	151	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

RPTN_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.024208 (rank : 214)
Query Neighborhood Hits	151	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SMCA4_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.118486 (rank : 115)
Query Neighborhood Hits	151	Target Neighborhood Hits	597	Shared Neighborhood Hits	52
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

ZNF22_MOUSE
θ value	2.36792 (rank : 108)	NC score	-0.002961 (rank : 250)
Query Neighborhood Hits	151	Target Neighborhood Hits	731	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ERU3, Q3TF83, Q8VEK7	Gene names	Znf22, Krox25, Krox26, Zfp422
Domain Architecture	No domain graphic available
Description	Zinc finger protein 22 (Zinc finger protein 422) (Krox-25 protein) (Krox-26 protein).

ADCY8_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.014076 (rank : 224)
Query Neighborhood Hits	151	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P97490	Gene names	Adcy8
Domain Architecture
Description	Adenylate cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type VIII) (ATP pyrophosphate-lyase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase).

CBP_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.160245 (rank : 94)
Query Neighborhood Hits	151	Target Neighborhood Hits	941	Shared Neighborhood Hits	49
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CREL1_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.011068 (rank : 229)
Query Neighborhood Hits	151	Target Neighborhood Hits	441	Shared Neighborhood Hits	8
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DPF1_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.230451 (rank : 51)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	66
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

SAFB2_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.011734 (rank : 228)
Query Neighborhood Hits	151	Target Neighborhood Hits	720	Shared Neighborhood Hits	21
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SFRS6_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.008963 (rank : 237)
Query Neighborhood Hits	151	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

SMRA3_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.058564 (rank : 188)
Query Neighborhood Hits	151	Target Neighborhood Hits	267	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

FMN2_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.021938 (rank : 215)
Query Neighborhood Hits	151	Target Neighborhood Hits	484	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MEGF6_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.001911 (rank : 244)
Query Neighborhood Hits	151	Target Neighborhood Hits	671	Shared Neighborhood Hits	7
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MTF2_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.160471 (rank : 93)
Query Neighborhood Hits	151	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.159557 (rank : 96)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

REQU_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.226498 (rank : 55)
Query Neighborhood Hits	151	Target Neighborhood Hits	523	Shared Neighborhood Hits	72
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

CENPB_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.017926 (rank : 220)
Query Neighborhood Hits	151	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

DNM3A_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.040279 (rank : 208)
Query Neighborhood Hits	151	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.040254 (rank : 209)
Query Neighborhood Hits	151	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

HUWE1_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.010891 (rank : 231)
Query Neighborhood Hits	151	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

MEGF9_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.010948 (rank : 230)
Query Neighborhood Hits	151	Target Neighborhood Hits	896	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

REQU_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.224894 (rank : 56)
Query Neighborhood Hits	151	Target Neighborhood Hits	519	Shared Neighborhood Hits	71
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SPDYA_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.015876 (rank : 223)
Query Neighborhood Hits	151	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q5IBH7, Q5IBH8, Q8C5T5	Gene names	Spdya, Spdy1
Domain Architecture	No domain graphic available
Description	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (mSpy/Ringo A).

THYG_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.007651 (rank : 238)
Query Neighborhood Hits	151	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TRPS1_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.007614 (rank : 239)
Query Neighborhood Hits	151	Target Neighborhood Hits	539	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

UHRF1_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.195050 (rank : 76)
Query Neighborhood Hits	151	Target Neighborhood Hits	272	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

AKP8L_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.012282 (rank : 226)
Query Neighborhood Hits	151	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

BRPF1_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.192689 (rank : 79)
Query Neighborhood Hits	151	Target Neighborhood Hits	259	Shared Neighborhood Hits	81
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

HMMR_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.001406 (rank : 245)
Query Neighborhood Hits	151	Target Neighborhood Hits	1178	Shared Neighborhood Hits	18
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IRX4_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.005633 (rank : 240)
Query Neighborhood Hits	151	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	P78413, Q9UHR2	Gene names	IRX4, IRXA3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

M3K12_MOUSE
θ value	6.88961 (rank : 135)	NC score	-0.005476 (rank : 252)
Query Neighborhood Hits	151	Target Neighborhood Hits	957	Shared Neighborhood Hits	7
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

RBBP6_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.035145 (rank : 210)
Query Neighborhood Hits	151	Target Neighborhood Hits	1135	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TTC14_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.020266 (rank : 217)
Query Neighborhood Hits	151	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

ZN335_HUMAN
θ value	6.88961 (rank : 138)	NC score	-0.001414 (rank : 248)
Query Neighborhood Hits	151	Target Neighborhood Hits	973	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ZN480_HUMAN
θ value	6.88961 (rank : 139)	NC score	-0.004165 (rank : 251)
Query Neighborhood Hits	151	Target Neighborhood Hits	744	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WV37, Q5JPG9, Q6P0Q4, Q8N1M5	Gene names	ZNF480
Domain Architecture	No domain graphic available
Description	Zinc finger protein 480.

CORIN_MOUSE
θ value	8.99809 (rank : 140)	NC score	-0.001561 (rank : 249)
Query Neighborhood Hits	151	Target Neighborhood Hits	451	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

EP300_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.161805 (rank : 92)
Query Neighborhood Hits	151	Target Neighborhood Hits	821	Shared Neighborhood Hits	55
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HTSF1_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.016000 (rank : 221)
Query Neighborhood Hits	151	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MATR3_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.019008 (rank : 219)
Query Neighborhood Hits	151	Target Neighborhood Hits	325	Shared Neighborhood Hits	20
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MSX1_HUMAN
θ value	8.99809 (rank : 144)	NC score	-0.000500 (rank : 246)
Query Neighborhood Hits	151	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

NARG1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.010671 (rank : 232)
Query Neighborhood Hits	151	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.010647 (rank : 233)
Query Neighborhood Hits	151	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NKTR_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.021164 (rank : 216)
Query Neighborhood Hits	151	Target Neighborhood Hits	658	Shared Neighborhood Hits	31
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RB6I2_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.003819 (rank : 243)
Query Neighborhood Hits	151	Target Neighborhood Hits	1584	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RGS14_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.005285 (rank : 241)
Query Neighborhood Hits	151	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

SOX13_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.020012 (rank : 218)
Query Neighborhood Hits	151	Target Neighborhood Hits	464	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ZHX2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.009382 (rank : 236)
Query Neighborhood Hits	151	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

AF10_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.056019 (rank : 197)
Query Neighborhood Hits	151	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.056182 (rank : 195)
Query Neighborhood Hits	151	Target Neighborhood Hits	182	Shared Neighborhood Hits	40
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.062975 (rank : 176)
Query Neighborhood Hits	151	Target Neighborhood Hits	230	Shared Neighborhood Hits	41
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

ATAD2_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.067413 (rank : 162)
Query Neighborhood Hits	151	Target Neighborhood Hits	322	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.064102 (rank : 172)
Query Neighborhood Hits	151	Target Neighborhood Hits	167	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BRD1_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.183274 (rank : 83)
Query Neighborhood Hits	151	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRD7_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.125549 (rank : 111)
Query Neighborhood Hits	151	Target Neighborhood Hits	94	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.120871 (rank : 112)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.153912 (rank : 100)
Query Neighborhood Hits	151	Target Neighborhood Hits	292	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.156656 (rank : 98)
Query Neighborhood Hits	151	Target Neighborhood Hits	422	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD9_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.118694 (rank : 114)
Query Neighborhood Hits	151	Target Neighborhood Hits	56	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.128389 (rank : 110)
Query Neighborhood Hits	151	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRPF3_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.188559 (rank : 81)
Query Neighborhood Hits	151	Target Neighborhood Hits	217	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BTAF1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.059234 (rank : 184)
Query Neighborhood Hits	151	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CHD1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.074585 (rank : 137)
Query Neighborhood Hits	151	Target Neighborhood Hits	337	Shared Neighborhood Hits	21
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.073147 (rank : 142)
Query Neighborhood Hits	151	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.074190 (rank : 138)
Query Neighborhood Hits	151	Target Neighborhood Hits	360	Shared Neighborhood Hits	18
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.073782 (rank : 140)
Query Neighborhood Hits	151	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.070168 (rank : 153)
Query Neighborhood Hits	151	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.072973 (rank : 143)
Query Neighborhood Hits	151	Target Neighborhood Hits	343	Shared Neighborhood Hits	19
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.072003 (rank : 150)
Query Neighborhood Hits	151	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DIDO1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.050032 (rank : 206)
Query Neighborhood Hits	151	Target Neighborhood Hits	960	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DNM3L_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.065177 (rank : 169)
Query Neighborhood Hits	151	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

EP400_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.066611 (rank : 166)
Query Neighborhood Hits	151	Target Neighborhood Hits	556	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.069945 (rank : 155)
Query Neighborhood Hits	151	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ERCC6_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.072792 (rank : 145)
Query Neighborhood Hits	151	Target Neighborhood Hits	247	Shared Neighborhood Hits	18
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

GCNL2_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.174643 (rank : 87)
Query Neighborhood Hits	151	Target Neighborhood Hits	159	Shared Neighborhood Hits	33
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.169239 (rank : 90)
Query Neighborhood Hits	151	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

HMG1X_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.088944 (rank : 127)
Query Neighborhood Hits	151	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.085570 (rank : 129)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.084873 (rank : 131)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.080789 (rank : 134)
Query Neighborhood Hits	151	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.081821 (rank : 133)
Query Neighborhood Hits	151	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.070075 (rank : 154)
Query Neighborhood Hits	151	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.071142 (rank : 151)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HRX_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.104197 (rank : 121)
Query Neighborhood Hits	151	Target Neighborhood Hits	825	Shared Neighborhood Hits	70
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ING1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.058856 (rank : 187)
Query Neighborhood Hits	151	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.057189 (rank : 193)
Query Neighborhood Hits	151	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.074062 (rank : 139)
Query Neighborhood Hits	151	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

ING2_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.075727 (rank : 136)
Query Neighborhood Hits	151	Target Neighborhood Hits	102	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING3_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.057459 (rank : 192)
Query Neighborhood Hits	151	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.052922 (rank : 201)
Query Neighborhood Hits	151	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING5_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.069495 (rank : 156)
Query Neighborhood Hits	151	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.067397 (rank : 163)
Query Neighborhood Hits	151	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

INOC1_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.061883 (rank : 180)
Query Neighborhood Hits	151	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.061940 (rank : 179)
Query Neighborhood Hits	151	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

IWS1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.053446 (rank : 200)
Query Neighborhood Hits	151	Target Neighborhood Hits	1241	Shared Neighborhood Hits	56
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JADE3_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.132510 (rank : 109)
Query Neighborhood Hits	151	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.135616 (rank : 107)
Query Neighborhood Hits	151	Target Neighborhood Hits	174	Shared Neighborhood Hits	60
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

MLL4_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.107225 (rank : 120)
Query Neighborhood Hits	151	Target Neighborhood Hits	722	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NIPBL_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.056352 (rank : 194)
Query Neighborhood Hits	151	Target Neighborhood Hits	1311	Shared Neighborhood Hits	59
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PCAF_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.180338 (rank : 85)
Query Neighborhood Hits	151	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PHF10_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.184854 (rank : 82)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.182980 (rank : 84)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF20_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.051021 (rank : 204)
Query Neighborhood Hits	151	Target Neighborhood Hits	513	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PML_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.136922 (rank : 106)
Query Neighborhood Hits	151	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.134712 (rank : 108)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	12
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RA54B_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.064490 (rank : 170)
Query Neighborhood Hits	151	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.064315 (rank : 171)
Query Neighborhood Hits	151	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.066540 (rank : 167)
Query Neighborhood Hits	151	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.065474 (rank : 168)
Query Neighborhood Hits	151	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RSF1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.238747 (rank : 46)
Query Neighborhood Hits	151	Target Neighborhood Hits	539	Shared Neighborhood Hits	74
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SMAL1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.057647 (rank : 191)
Query Neighborhood Hits	151	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.059155 (rank : 186)
Query Neighborhood Hits	151	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.067804 (rank : 158)
Query Neighborhood Hits	151	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.067309 (rank : 164)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.118805 (rank : 113)
Query Neighborhood Hits	151	Target Neighborhood Hits	503	Shared Neighborhood Hits	49
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA5_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.067461 (rank : 160)
Query Neighborhood Hits	151	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.067452 (rank : 161)
Query Neighborhood Hits	151	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRA3_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.054824 (rank : 198)
Query Neighborhood Hits	151	Target Neighborhood Hits	265	Shared Neighborhood Hits	14
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRCD_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.063566 (rank : 174)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.063671 (rank : 173)
Query Neighborhood Hits	151	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

TAF3_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.068446 (rank : 157)
Query Neighborhood Hits	151	Target Neighborhood Hits	568	Shared Neighborhood Hits	59
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.061809 (rank : 182)
Query Neighborhood Hits	151	Target Neighborhood Hits	463	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI18_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.059187 (rank : 185)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.059597 (rank : 183)
Query Neighborhood Hits	151	Target Neighborhood Hits	292	Shared Neighborhood Hits	15
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI29_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.067197 (rank : 165)
Query Neighborhood Hits	151	Target Neighborhood Hits	273	Shared Neighborhood Hits	9
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.063100 (rank : 175)
Query Neighborhood Hits	151	Target Neighborhood Hits	306	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI36_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.077055 (rank : 135)
Query Neighborhood Hits	151	Target Neighborhood Hits	282	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.072380 (rank : 147)
Query Neighborhood Hits	151	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI37_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.058403 (rank : 190)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.058499 (rank : 189)
Query Neighborhood Hits	151	Target Neighborhood Hits	316	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.088546 (rank : 128)
Query Neighborhood Hits	151	Target Neighborhood Hits	283	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.091868 (rank : 126)
Query Neighborhood Hits	151	Target Neighborhood Hits	316	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI45_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.172399 (rank : 88)
Query Neighborhood Hits	151	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.170737 (rank : 89)
Query Neighborhood Hits	151	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.073579 (rank : 141)
Query Neighborhood Hits	151	Target Neighborhood Hits	291	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.072199 (rank : 149)
Query Neighborhood Hits	151	Target Neighborhood Hits	287	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI55_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.052842 (rank : 202)
Query Neighborhood Hits	151	Target Neighborhood Hits	292	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI56_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.115489 (rank : 118)
Query Neighborhood Hits	151	Target Neighborhood Hits	339	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.116586 (rank : 117)
Query Neighborhood Hits	151	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI63_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.070902 (rank : 152)
Query Neighborhood Hits	151	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.061829 (rank : 181)
Query Neighborhood Hits	151	Target Neighborhood Hits	240	Shared Neighborhood Hits	12
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.072662 (rank : 146)
Query Neighborhood Hits	151	Target Neighborhood Hits	345	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.072891 (rank : 144)
Query Neighborhood Hits	151	Target Neighborhood Hits	361	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM2_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.096163 (rank : 122)
Query Neighborhood Hits	151	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.096120 (rank : 123)
Query Neighborhood Hits	151	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.093674 (rank : 125)
Query Neighborhood Hits	151	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.095500 (rank : 124)
Query Neighborhood Hits	151	Target Neighborhood Hits	351	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TTF2_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.053521 (rank : 199)
Query Neighborhood Hits	151	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

UHRF2_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.157311 (rank : 97)
Query Neighborhood Hits	151	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

Hits sorted by NC score

LY10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	151
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SP110_HUMAN
NC score	0.874152 (rank : 2)	θ value	2.3998e-69 (rank : 3)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

IPR1_MOUSE
NC score	0.616979 (rank : 3)	θ value	1.86321e-21 (rank : 4)
Query Neighborhood Hits	151	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

AIRE_HUMAN
NC score	0.595718 (rank : 4)	θ value	1.2105e-12 (rank : 13)
Query Neighborhood Hits	151	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.595451 (rank : 5)	θ value	1.2105e-12 (rank : 14)
Query Neighborhood Hits	151	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

SP100_MOUSE
NC score	0.578708 (rank : 6)	θ value	5.42112e-21 (rank : 6)
Query Neighborhood Hits	151	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

S100R_MOUSE
NC score	0.576386 (rank : 7)	θ value	9.56915e-18 (rank : 10)
Query Neighborhood Hits	151	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

TRI66_HUMAN
NC score	0.571145 (rank : 8)	θ value	4.74913e-17 (rank : 11)
Query Neighborhood Hits	151	Target Neighborhood Hits	479	Shared Neighborhood Hits	88
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
NC score	0.570793 (rank : 9)	θ value	1.80466e-16 (rank : 12)
Query Neighborhood Hits	151	Target Neighborhood Hits	491	Shared Neighborhood Hits	89
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_MOUSE
NC score	0.567728 (rank : 10)	θ value	3.17815e-21 (rank : 5)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	86
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.559089 (rank : 11)	θ value	9.24701e-21 (rank : 7)
Query Neighborhood Hits	151	Target Neighborhood Hits	327	Shared Neighborhood Hits	86
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1G_HUMAN
NC score	0.531835 (rank : 12)	θ value	4.58923e-20 (rank : 8)
Query Neighborhood Hits	151	Target Neighborhood Hits	410	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.529545 (rank : 13)	θ value	1.02238e-19 (rank : 9)
Query Neighborhood Hits	151	Target Neighborhood Hits	498	Shared Neighborhood Hits	86
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SP100_HUMAN
NC score	0.494843 (rank : 14)	θ value	1.14825e-79 (rank : 2)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

TIF1B_MOUSE
NC score	0.472979 (rank : 15)	θ value	1.25267e-09 (rank : 18)
Query Neighborhood Hits	151	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1B_HUMAN
NC score	0.470911 (rank : 16)	θ value	5.62301e-10 (rank : 17)
Query Neighborhood Hits	151	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PF21A_MOUSE
NC score	0.462262 (rank : 17)	θ value	2.88788e-06 (rank : 25)
Query Neighborhood Hits	151	Target Neighborhood Hits	285	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PHF12_MOUSE
NC score	0.459351 (rank : 18)	θ value	4.45536e-07 (rank : 21)
Query Neighborhood Hits	151	Target Neighborhood Hits	172	Shared Neighborhood Hits	68
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.459217 (rank : 19)	θ value	4.45536e-07 (rank : 20)
Query Neighborhood Hits	151	Target Neighborhood Hits	174	Shared Neighborhood Hits	67
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21A_HUMAN
NC score	0.454477 (rank : 20)	θ value	2.88788e-06 (rank : 24)
Query Neighborhood Hits	151	Target Neighborhood Hits	303	Shared Neighborhood Hits	73
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PKCB1_HUMAN
NC score	0.409906 (rank : 21)	θ value	0.000602161 (rank : 34)
Query Neighborhood Hits	151	Target Neighborhood Hits	488	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_HUMAN
NC score	0.404291 (rank : 22)	θ value	0.00298849 (rank : 36)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BPTF_HUMAN
NC score	0.393232 (rank : 23)	θ value	6.87365e-08 (rank : 19)
Query Neighborhood Hits	151	Target Neighborhood Hits	786	Shared Neighborhood Hits	91
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DEAF1_HUMAN
NC score	0.373945 (rank : 24)	θ value	2.52405e-10 (rank : 15)
Query Neighborhood Hits	151	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
NC score	0.373628 (rank : 25)	θ value	2.52405e-10 (rank : 16)
Query Neighborhood Hits	151	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

PF21B_MOUSE
NC score	0.370315 (rank : 26)	θ value	0.0330416 (rank : 50)
Query Neighborhood Hits	151	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BAZ2A_HUMAN
NC score	0.343154 (rank : 27)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	151	Target Neighborhood Hits	780	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
NC score	0.338794 (rank : 28)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	151	Target Neighborhood Hits	744	Shared Neighborhood Hits	91
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ1B_MOUSE
NC score	0.319303 (rank : 29)	θ value	0.125558 (rank : 63)
Query Neighborhood Hits	151	Target Neighborhood Hits	394	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2B_HUMAN
NC score	0.312561 (rank : 30)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	151	Target Neighborhood Hits	803	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ1A_HUMAN
NC score	0.310951 (rank : 31)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	151	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

NSD1_MOUSE
NC score	0.302665 (rank : 32)	θ value	0.000158464 (rank : 31)
Query Neighborhood Hits	151	Target Neighborhood Hits	472	Shared Neighborhood Hits	73
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.300037 (rank : 33)	θ value	0.000158464 (rank : 30)
Query Neighborhood Hits	151	Target Neighborhood Hits	427	Shared Neighborhood Hits	71
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

BAZ1B_HUMAN
NC score	0.299481 (rank : 34)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	151	Target Neighborhood Hits	701	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

ZMY11_HUMAN
NC score	0.295726 (rank : 35)	θ value	0.0736092 (rank : 59)
Query Neighborhood Hits	151	Target Neighborhood Hits	201	Shared Neighborhood Hits	68
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
NC score	0.291012 (rank : 36)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	151	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CHD5_HUMAN
NC score	0.281556 (rank : 37)	θ value	4.92598e-06 (rank : 27)
Query Neighborhood Hits	151	Target Neighborhood Hits	349	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_HUMAN
NC score	0.278619 (rank : 38)	θ value	2.21117e-06 (rank : 22)
Query Neighborhood Hits	151	Target Neighborhood Hits	365	Shared Neighborhood Hits	76
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.277074 (rank : 39)	θ value	2.21117e-06 (rank : 23)
Query Neighborhood Hits	151	Target Neighborhood Hits	408	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.272414 (rank : 40)	θ value	4.92598e-06 (rank : 26)
Query Neighborhood Hits	151	Target Neighborhood Hits	397	Shared Neighborhood Hits	74
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

GMEB1_HUMAN
NC score	0.261003 (rank : 41)	θ value	3.19293e-05 (rank : 28)
Query Neighborhood Hits	151	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

GMEB1_MOUSE
NC score	0.260166 (rank : 42)	θ value	4.1701e-05 (rank : 29)
Query Neighborhood Hits	151	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB2_MOUSE
NC score	0.252916 (rank : 43)	θ value	0.00020696 (rank : 33)
Query Neighborhood Hits	151	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

GMEB2_HUMAN
NC score	0.252680 (rank : 44)	θ value	0.00020696 (rank : 32)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

BRD2_HUMAN
NC score	0.245765 (rank : 45)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	151	Target Neighborhood Hits	242	Shared Neighborhood Hits	42
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

RSF1_HUMAN
NC score	0.238747 (rank : 46)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	151	Target Neighborhood Hits	539	Shared Neighborhood Hits	74
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BRD3_HUMAN
NC score	0.236360 (rank : 47)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	151	Target Neighborhood Hits	369	Shared Neighborhood Hits	42
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
NC score	0.236283 (rank : 48)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	151	Target Neighborhood Hits	402	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

MYST4_MOUSE
NC score	0.233428 (rank : 49)	θ value	0.0563607 (rank : 56)
Query Neighborhood Hits	151	Target Neighborhood Hits	416	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

BRDT_HUMAN
NC score	0.231631 (rank : 50)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	151	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

DPF1_HUMAN
NC score	0.230451 (rank : 51)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	66
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

BRDT_MOUSE
NC score	0.228937 (rank : 52)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	151	Target Neighborhood Hits	243	Shared Neighborhood Hits	36
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

PHF1_HUMAN
NC score	0.227777 (rank : 53)	θ value	0.000786445 (rank : 35)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

DPF1_MOUSE
NC score	0.227492 (rank : 54)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	151	Target Neighborhood Hits	491	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.226498 (rank : 55)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	151	Target Neighborhood Hits	523	Shared Neighborhood Hits	72
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.224894 (rank : 56)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	151	Target Neighborhood Hits	519	Shared Neighborhood Hits	71
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

MYST4_HUMAN
NC score	0.224857 (rank : 57)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	151	Target Neighborhood Hits	671	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST3_MOUSE
NC score	0.224690 (rank : 58)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	151	Target Neighborhood Hits	688	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PHF1_MOUSE
NC score	0.222788 (rank : 59)	θ value	0.00298849 (rank : 37)
Query Neighborhood Hits	151	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

BRD4_HUMAN
NC score	0.222456 (rank : 60)	θ value	0.00665767 (rank : 40)
Query Neighborhood Hits	151	Target Neighborhood Hits	851	Shared Neighborhood Hits	52
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MYST3_HUMAN
NC score	0.222078 (rank : 61)	θ value	0.0148317 (rank : 46)
Query Neighborhood Hits	151	Target Neighborhood Hits	772	Shared Neighborhood Hits	74
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

BRD4_MOUSE
NC score	0.220958 (rank : 62)	θ value	0.0148317 (rank : 45)
Query Neighborhood Hits	151	Target Neighborhood Hits	845	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

JAD1D_HUMAN
NC score	0.220381 (rank : 63)	θ value	0.0736092 (rank : 57)
Query Neighborhood Hits	151	Target Neighborhood Hits	147	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PHF22_MOUSE
NC score	0.217712 (rank : 64)	θ value	0.0736092 (rank : 58)
Query Neighborhood Hits	151	Target Neighborhood Hits	89	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

CECR2_HUMAN
NC score	0.216177 (rank : 65)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	151	Target Neighborhood Hits	543	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

JAD1D_MOUSE
NC score	0.216017 (rank : 66)	θ value	0.0193708 (rank : 49)
Query Neighborhood Hits	151	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PHF22_HUMAN
NC score	0.214629 (rank : 67)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	151	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

JAD1C_MOUSE
NC score	0.206900 (rank : 68)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	151	Target Neighborhood Hits	164	Shared Neighborhood Hits	57
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.206304 (rank : 69)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	151	Target Neighborhood Hits	187	Shared Neighborhood Hits	57
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

MLL3_MOUSE
NC score	0.205564 (rank : 70)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	151	Target Neighborhood Hits	1399	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

JAD1A_HUMAN
NC score	0.204498 (rank : 71)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	151	Target Neighborhood Hits	328	Shared Neighborhood Hits	66
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

TAF1_HUMAN
NC score	0.202731 (rank : 72)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	38
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

MLL2_HUMAN
NC score	0.202239 (rank : 73)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	151	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHF14_MOUSE
NC score	0.199587 (rank : 74)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	151	Target Neighborhood Hits	342	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.198036 (rank : 75)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	151	Target Neighborhood Hits	447	Shared Neighborhood Hits	72
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

UHRF1_HUMAN
NC score	0.195050 (rank : 76)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	151	Target Neighborhood Hits	272	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

TAF1L_HUMAN
NC score	0.193726 (rank : 77)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	151	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

MLL3_HUMAN
NC score	0.193067 (rank : 78)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	151	Target Neighborhood Hits	1644	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BRPF1_HUMAN
NC score	0.192689 (rank : 79)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	151	Target Neighborhood Hits	259	Shared Neighborhood Hits	81
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

UHRF1_MOUSE
NC score	0.190139 (rank : 80)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	151	Target Neighborhood Hits	278	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BRPF3_HUMAN
NC score	0.188559 (rank : 81)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	151	Target Neighborhood Hits	217	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

PHF10_HUMAN
NC score	0.184854 (rank : 82)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

BRD1_HUMAN
NC score	0.183274 (rank : 83)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	151	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

PHF10_MOUSE
NC score	0.182980 (rank : 84)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PCAF_HUMAN
NC score	0.180338 (rank : 85)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	151	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PB1_HUMAN
NC score	0.177919 (rank : 86)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	151	Target Neighborhood Hits	261	Shared Neighborhood Hits	40
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

GCNL2_HUMAN
NC score	0.174643 (rank : 87)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	151	Target Neighborhood Hits	159	Shared Neighborhood Hits	33
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

TRI45_HUMAN
NC score	0.172399 (rank : 88)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	151	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
NC score	0.170737 (rank : 89)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	151	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

GCNL2_MOUSE
NC score	0.169239 (rank : 90)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	151	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

CBP_MOUSE
NC score	0.166881 (rank : 91)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	151	Target Neighborhood Hits	1051	Shared Neighborhood Hits	59
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EP300_HUMAN
NC score	0.161805 (rank : 92)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	151	Target Neighborhood Hits	821	Shared Neighborhood Hits	55
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MTF2_HUMAN
NC score	0.160471 (rank : 93)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	151	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

CBP_HUMAN
NC score	0.160245 (rank : 94)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	151	Target Neighborhood Hits	941	Shared Neighborhood Hits	49
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

UHRF2_MOUSE
NC score	0.160033 (rank : 95)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	151	Target Neighborhood Hits	275	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MTF2_MOUSE
NC score	0.159557 (rank : 96)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

UHRF2_HUMAN
NC score	0.157311 (rank : 97)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	151	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

BRD8_MOUSE
NC score	0.156656 (rank : 98)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	151	Target Neighborhood Hits	422	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ATRX_MOUSE
NC score	0.156288 (rank : 99)	θ value	0.0148317 (rank : 44)
Query Neighborhood Hits	151	Target Neighborhood Hits	682	Shared Neighborhood Hits	54
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BRD8_HUMAN
NC score	0.153912 (rank : 100)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	151	Target Neighborhood Hits	292	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

ATRX_HUMAN
NC score	0.148296 (rank : 101)	θ value	0.0193708 (rank : 48)
Query Neighborhood Hits	151	Target Neighborhood Hits	842	Shared Neighborhood Hits	64
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

JADE2_HUMAN
NC score	0.145810 (rank : 102)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	151	Target Neighborhood Hits	199	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE1_HUMAN
NC score	0.142968 (rank : 103)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	151	Target Neighborhood Hits	140	Shared Neighborhood Hits	58
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.142718 (rank : 104)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	151	Target Neighborhood Hits	160	Shared Neighborhood Hits	58
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_MOUSE
NC score	0.139613 (rank : 105)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	151	Target Neighborhood Hits	560	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PML_HUMAN
NC score	0.136922 (rank : 106)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	151	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

JADE3_MOUSE
NC score	0.135616 (rank : 107)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	151	Target Neighborhood Hits	174	Shared Neighborhood Hits	60
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

PML_MOUSE
NC score	0.134712 (rank : 108)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	12
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

JADE3_HUMAN
NC score	0.132510 (rank : 109)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	151	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

BRD9_MOUSE
NC score	0.128389 (rank : 110)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	151	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD7_HUMAN
NC score	0.125549 (rank : 111)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	151	Target Neighborhood Hits	94	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
NC score	0.120871 (rank : 112)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

SMCA2_HUMAN
NC score	0.118805 (rank : 113)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	151	Target Neighborhood Hits	503	Shared Neighborhood Hits	49
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

BRD9_HUMAN
NC score	0.118694 (rank : 114)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	151	Target Neighborhood Hits	56	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

SMCA4_HUMAN
NC score	0.118486 (rank : 115)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	151	Target Neighborhood Hits	597	Shared Neighborhood Hits	52
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

BRWD1_MOUSE
NC score	0.117936 (rank : 116)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	151	Target Neighborhood Hits	478	Shared Neighborhood Hits	43
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

TRI56_MOUSE
NC score	0.116586 (rank : 117)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	151	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.115489 (rank : 118)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	151	Target Neighborhood Hits	339	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

BRWD1_HUMAN
NC score	0.111759 (rank : 119)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	151	Target Neighborhood Hits	448	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

MLL4_HUMAN
NC score	0.107225 (rank : 120)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	151	Target Neighborhood Hits	722	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.104197 (rank : 121)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	151	Target Neighborhood Hits	825	Shared Neighborhood Hits	70
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TRIM2_HUMAN
NC score	0.096163 (rank : 122)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	151	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.096120 (rank : 123)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	151	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_MOUSE
NC score	0.095500 (rank : 124)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	151	Target Neighborhood Hits	351	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.093674 (rank : 125)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	151	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI42_MOUSE
NC score	0.091868 (rank : 126)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	151	Target Neighborhood Hits	316	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

HMG1X_HUMAN
NC score	0.088944 (rank : 127)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	151	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

TRI42_HUMAN
NC score	0.088546 (rank : 128)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	151	Target Neighborhood Hits	283	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

HMGB1_HUMAN
NC score	0.085570 (rank : 129)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

SON_HUMAN
NC score	0.085154 (rank : 130)	θ value	0.0113563 (rank : 43)
Query Neighborhood Hits	151	Target Neighborhood Hits	1568	Shared Neighborhood Hits	56
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

HMGB1_MOUSE
NC score	0.084873 (rank : 131)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

SON_MOUSE
NC score	0.084370 (rank : 132)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	151	Target Neighborhood Hits	957	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

HMGB2_MOUSE
NC score	0.081821 (rank : 133)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	151	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_HUMAN
NC score	0.080789 (rank : 134)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	151	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

TRI36_HUMAN
NC score	0.077055 (rank : 135)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	151	Target Neighborhood Hits	282	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

ING2_MOUSE
NC score	0.075727 (rank : 136)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	151	Target Neighborhood Hits	102	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

CHD1_HUMAN
NC score	0.074585 (rank : 137)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	151	Target Neighborhood Hits	337	Shared Neighborhood Hits	21
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
NC score	0.074190 (rank : 138)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	151	Target Neighborhood Hits	360	Shared Neighborhood Hits	18
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

ING2_HUMAN
NC score	0.074062 (rank : 139)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	151	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

CHD6_HUMAN
NC score	0.073782 (rank : 140)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	151	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

TRI46_HUMAN
NC score	0.073579 (rank : 141)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	151	Target Neighborhood Hits	291	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

CHD1_MOUSE
NC score	0.073147 (rank : 142)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	151	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD9_HUMAN
NC score	0.072973 (rank : 143)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	151	Target Neighborhood Hits	343	Shared Neighborhood Hits	19
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

TRIM1_MOUSE
NC score	0.072891 (rank : 144)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	151	Target Neighborhood Hits	361	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

ERCC6_HUMAN
NC score	0.072792 (rank : 145)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	151	Target Neighborhood Hits	247	Shared Neighborhood Hits	18
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

TRIM1_HUMAN
NC score	0.072662 (rank : 146)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	151	Target Neighborhood Hits	345	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI36_MOUSE
NC score	0.072380 (rank : 147)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	151	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

K1045_MOUSE
NC score	0.072312 (rank : 148)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	151	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TL4, Q8BH08	Gene names	Kiaa1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

TRI46_MOUSE
NC score	0.072199 (rank : 149)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	151	Target Neighborhood Hits	287	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

CHD9_MOUSE
NC score	0.072003 (rank : 150)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	151	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

HMGB3_MOUSE
NC score	0.071142 (rank : 151)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

TRI63_HUMAN
NC score	0.070902 (rank : 152)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	151	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

CHD8_HUMAN
NC score	0.070168 (rank : 153)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	151	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

HMGB3_HUMAN
NC score	0.070075 (rank : 154)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	151	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

EP400_MOUSE
NC score	0.069945 (rank : 155)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	151	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ING5_HUMAN
NC score	0.069495 (rank : 156)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	151	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

TAF3_HUMAN
NC score	0.068446 (rank : 157)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	151	Target Neighborhood Hits	568	Shared Neighborhood Hits	59
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SMCA1_HUMAN
NC score	0.067804 (rank : 158)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	151	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SFR11_HUMAN
NC score	0.067659 (rank : 159)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SMCA5_HUMAN
NC score	0.067461 (rank : 160)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	151	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
NC score	0.067452 (rank : 161)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	151	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

ATAD2_HUMAN
NC score	0.067413 (rank : 162)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	151	Target Neighborhood Hits	322	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ING5_MOUSE
NC score	0.067397 (rank : 163)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	151	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

SMCA1_MOUSE
NC score	0.067309 (rank : 164)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

TRI29_HUMAN
NC score	0.067197 (rank : 165)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	151	Target Neighborhood Hits	273	Shared Neighborhood Hits	9
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

EP400_HUMAN
NC score	0.066611 (rank : 166)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	151	Target Neighborhood Hits	556	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

RAD54_HUMAN
NC score	0.066540 (rank : 167)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	151	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
NC score	0.065474 (rank : 168)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	151	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

DNM3L_MOUSE
NC score	0.065177 (rank : 169)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	151	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

RA54B_HUMAN
NC score	0.064490 (rank : 170)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	151	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
NC score	0.064315 (rank : 171)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	151	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

ATAD2_MOUSE
NC score	0.064102 (rank : 172)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	151	Target Neighborhood Hits	167	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SMRCD_MOUSE
NC score	0.063671 (rank : 173)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	151	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.063566 (rank : 174)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

TRI29_MOUSE
NC score	0.063100 (rank : 175)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	151	Target Neighborhood Hits	306	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

AF17_HUMAN
NC score	0.062975 (rank : 176)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	151	Target Neighborhood Hits	230	Shared Neighborhood Hits	41
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

K1045_HUMAN
NC score	0.062240 (rank : 177)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	151	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPV7, Q58FE9, Q5T662	Gene names	KIAA1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

IWS1_MOUSE
NC score	0.062165 (rank : 178)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	151	Target Neighborhood Hits	1258	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

INOC1_MOUSE
NC score	0.061940 (rank : 179)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	151	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.061883 (rank : 180)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	151	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

TRI63_MOUSE
NC score	0.061829 (rank : 181)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	151	Target Neighborhood Hits	240	Shared Neighborhood Hits	12
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TAF3_MOUSE
NC score	0.061809 (rank : 182)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	151	Target Neighborhood Hits	463	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI18_MOUSE
NC score	0.059597 (rank : 183)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	151	Target Neighborhood Hits	292	Shared Neighborhood Hits	15
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

BTAF1_HUMAN
NC score	0.059234 (rank : 184)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	151	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

TRI18_HUMAN
NC score	0.059187 (rank : 185)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

SMAL1_MOUSE
NC score	0.059155 (rank : 186)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	151	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

ING1_HUMAN
NC score	0.058856 (rank : 187)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	151	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

SMRA3_MOUSE
NC score	0.058564 (rank : 188)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	151	Target Neighborhood Hits	267	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRI37_MOUSE
NC score	0.058499 (rank : 189)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	151	Target Neighborhood Hits	316	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.058403 (rank : 190)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

SMAL1_HUMAN
NC score	0.057647 (rank : 191)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	151	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

ING3_HUMAN
NC score	0.057459 (rank : 192)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	151	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING1_MOUSE
NC score	0.057189 (rank : 193)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	151	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

NIPBL_HUMAN
NC score	0.056352 (rank : 194)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	151	Target Neighborhood Hits	1311	Shared Neighborhood Hits	59
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

AF10_MOUSE
NC score	0.056182 (rank : 195)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	151	Target Neighborhood Hits	182	Shared Neighborhood Hits	40
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

DSPP_HUMAN
NC score	0.056100 (rank : 196)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	151	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AF10_HUMAN
NC score	0.056019 (rank : 197)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	151	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

SMRA3_HUMAN
NC score	0.054824 (rank : 198)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	151	Target Neighborhood Hits	265	Shared Neighborhood Hits	14
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TTF2_MOUSE
NC score	0.053521 (rank : 199)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	151	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

IWS1_HUMAN
NC score	0.053446 (rank : 200)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	151	Target Neighborhood Hits	1241	Shared Neighborhood Hits	56
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ING3_MOUSE
NC score	0.052922 (rank : 201)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	151	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

TRI55_HUMAN
NC score	0.052842 (rank : 202)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	151	Target Neighborhood Hits	292	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

ZCPW1_MOUSE
NC score	0.052678 (rank : 203)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	151	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

PHF20_MOUSE
NC score	0.051021 (rank : 204)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	151	Target Neighborhood Hits	513	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

XRCC4_HUMAN
NC score	0.050373 (rank : 205)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

DIDO1_HUMAN
NC score	0.050032 (rank : 206)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	151	Target Neighborhood Hits	960	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

RANB3_MOUSE
NC score	0.043143 (rank : 207)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

DNM3A_HUMAN
NC score	0.040279 (rank : 208)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	151	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
NC score	0.040254 (rank : 209)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	151	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

RBBP6_HUMAN
NC score	0.035145 (rank : 210)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	151	Target Neighborhood Hits	1135	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RTN1_MOUSE
NC score	0.033452 (rank : 211)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	151	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

AMPH_MOUSE
NC score	0.032030 (rank : 212)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	151	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

SVIL_HUMAN
NC score	0.028066 (rank : 213)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	9
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

RPTN_MOUSE
NC score	0.024208 (rank : 214)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	151	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

FMN2_HUMAN
NC score	0.021938 (rank : 215)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	151	Target Neighborhood Hits	484	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

NKTR_HUMAN
NC score	0.021164 (rank : 216)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	151	Target Neighborhood Hits	658	Shared Neighborhood Hits	31
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TTC14_HUMAN
NC score	0.020266 (rank : 217)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	151	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

SOX13_HUMAN
NC score	0.020012 (rank : 218)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	151	Target Neighborhood Hits	464	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

MATR3_HUMAN
NC score	0.019008 (rank : 219)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	151	Target Neighborhood Hits	325	Shared Neighborhood Hits	20
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

CENPB_MOUSE
NC score	0.017926 (rank : 220)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	151	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

HTSF1_MOUSE
NC score	0.016000 (rank : 221)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	151	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

ADCY8_HUMAN
NC score	0.015982 (rank : 222)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	151	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P40145	Gene names	ADCY8
Domain Architecture
Description	Adenylate cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type VIII) (ATP pyrophosphate-lyase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase).

SPDYA_MOUSE
NC score	0.015876 (rank : 223)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	151	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q5IBH7, Q5IBH8, Q8C5T5	Gene names	Spdya, Spdy1
Domain Architecture	No domain graphic available
Description	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (mSpy/Ringo A).

ADCY8_MOUSE
NC score	0.014076 (rank : 224)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	151	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P97490	Gene names	Adcy8
Domain Architecture
Description	Adenylate cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type VIII) (ATP pyrophosphate-lyase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase).

NDF2_MOUSE
NC score	0.013772 (rank : 225)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	151	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

AKP8L_HUMAN
NC score	0.012282 (rank : 226)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	151	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

SPB8_MOUSE
NC score	0.011943 (rank : 227)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	151	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	O08800	Gene names	Serpinb8
Domain Architecture	No domain graphic available
Description	Serpin B8.

SAFB2_HUMAN
NC score	0.011734 (rank : 228)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	151	Target Neighborhood Hits	720	Shared Neighborhood Hits	21
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

CREL1_HUMAN
NC score	0.011068 (rank : 229)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	151	Target Neighborhood Hits	441	Shared Neighborhood Hits	8
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MEGF9_MOUSE
NC score	0.010948 (rank : 230)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	151	Target Neighborhood Hits	896	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

HUWE1_HUMAN
NC score	0.010891 (rank : 231)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	151	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

NARG1_HUMAN
NC score	0.010671 (rank : 232)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	151	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
NC score	0.010647 (rank : 233)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	151	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

MYO7A_HUMAN
NC score	0.010010 (rank : 234)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	151	Target Neighborhood Hits	209	Shared Neighborhood Hits	5
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
NC score	0.009771 (rank : 235)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	151	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

ZHX2_MOUSE
NC score	0.009382 (rank : 236)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	151	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

SFRS6_HUMAN
NC score	0.008963 (rank : 237)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	151	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

THYG_HUMAN
NC score	0.007651 (rank : 238)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	151	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TRPS1_HUMAN
NC score	0.007614 (rank : 239)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	151	Target Neighborhood Hits	539	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

IRX4_HUMAN
NC score	0.005633 (rank : 240)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	151	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	P78413, Q9UHR2	Gene names	IRX4, IRXA3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

RGS14_HUMAN
NC score	0.005285 (rank : 241)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	151	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

DLL1_HUMAN
NC score	0.004300 (rank : 242)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	151	Target Neighborhood Hits	455	Shared Neighborhood Hits	9
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

RB6I2_HUMAN
NC score	0.003819 (rank : 243)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	151	Target Neighborhood Hits	1584	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

MEGF6_HUMAN
NC score	0.001911 (rank : 244)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	151	Target Neighborhood Hits	671	Shared Neighborhood Hits	7
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

HMMR_MOUSE
NC score	0.001406 (rank : 245)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	151	Target Neighborhood Hits	1178	Shared Neighborhood Hits	18
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MSX1_HUMAN
NC score	-0.000500 (rank : 246)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	151	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

MTF1_MOUSE
NC score	-0.001067 (rank : 247)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	151	Target Neighborhood Hits	785	Shared Neighborhood Hits	10
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

ZN335_HUMAN
NC score	-0.001414 (rank : 248)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	151	Target Neighborhood Hits	973	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

CORIN_MOUSE
NC score	-0.001561 (rank : 249)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	151	Target Neighborhood Hits	451	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ZNF22_MOUSE
NC score	-0.002961 (rank : 250)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	151	Target Neighborhood Hits	731	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ERU3, Q3TF83, Q8VEK7	Gene names	Znf22, Krox25, Krox26, Zfp422
Domain Architecture	No domain graphic available
Description	Zinc finger protein 22 (Zinc finger protein 422) (Krox-25 protein) (Krox-26 protein).

ZN480_HUMAN
NC score	-0.004165 (rank : 251)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	151	Target Neighborhood Hits	744	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WV37, Q5JPG9, Q6P0Q4, Q8N1M5	Gene names	ZNF480
Domain Architecture	No domain graphic available
Description	Zinc finger protein 480.

M3K12_MOUSE
NC score	-0.005476 (rank : 252)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	151	Target Neighborhood Hits	957	Shared Neighborhood Hits	7
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).