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Network neighborhood for query Sequence : SP100_MOUSE

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SP100_MOUSE
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SP100_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

S100R_MOUSE
θ value	1.01059e-59 (rank : 2)	NC score	0.939161 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

SP100_HUMAN
θ value	9.81109e-47 (rank : 3)	NC score	0.572754 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

LY10_HUMAN
θ value	5.42112e-21 (rank : 4)	NC score	0.578708 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

IPR1_MOUSE
θ value	1.13037e-18 (rank : 5)	NC score	0.706085 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

SP110_HUMAN
θ value	1.47631e-18 (rank : 6)	NC score	0.589505 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

DEAF1_HUMAN
θ value	0.000461057 (rank : 7)	NC score	0.310519 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.308028 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

DSPP_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.045076 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	645	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

JHD2C_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.040011 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	279	Shared Neighborhood Hits	6
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

CD2L5_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.005928 (rank : 41)
Query Neighborhood Hits	32	Target Neighborhood Hits	987	Shared Neighborhood Hits	5
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

RHG12_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.019048 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

PCDGH_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.005039 (rank : 43)
Query Neighborhood Hits	32	Target Neighborhood Hits	164	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5G0, Q9Y5C6	Gene names	PCDHGB5
Domain Architecture
Description	Protocadherin gamma B5 precursor (PCDH-gamma-B5).

SFRIP_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.034250 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	530	Shared Neighborhood Hits	9
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

JHD2C_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.038442 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

LETM1_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.026136 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	338	Shared Neighborhood Hits	3
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

TBCD5_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.025257 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

BOP1_MOUSE
θ value	4.03905 (rank : 18)	NC score	0.016921 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	267	Shared Neighborhood Hits	2
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

PCLO_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.011684 (rank : 38)
Query Neighborhood Hits	32	Target Neighborhood Hits	2046	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PROX1_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.023866 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

RPGF2_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.016877 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

AP3B1_MOUSE
θ value	5.27518 (rank : 22)	NC score	0.014654 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CA106_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.019005 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

MARK4_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.001228 (rank : 44)
Query Neighborhood Hits	32	Target Neighborhood Hits	898	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

NFAC3_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.013078 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

TACC3_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.011173 (rank : 39)
Query Neighborhood Hits	32	Target Neighborhood Hits	607	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

AIRE_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.095790 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

SRRM2_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.022607 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	1296	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.018032 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	1470	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CTR9_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.013051 (rank : 37)
Query Neighborhood Hits	32	Target Neighborhood Hits	383	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

ITCH_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.005853 (rank : 42)
Query Neighborhood Hits	32	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

USH1C_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.007954 (rank : 40)
Query Neighborhood Hits	32	Target Neighborhood Hits	557	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.094847 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

GMEB1_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.103322 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

GMEB1_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.103968 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB2_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.103435 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.103396 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

HMG1X_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.104673 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	97	Shared Neighborhood Hits	1
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB1_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.100075 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.100089 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.093403 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	114	Shared Neighborhood Hits	1
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.094136 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	111	Shared Neighborhood Hits	1
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.082168 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	86	Shared Neighborhood Hits	1
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.082548 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	88	Shared Neighborhood Hits	1
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

Hits sorted by NC score

SP100_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

S100R_MOUSE
NC score	0.939161 (rank : 2)	θ value	1.01059e-59 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

IPR1_MOUSE
NC score	0.706085 (rank : 3)	θ value	1.13037e-18 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

SP110_HUMAN
NC score	0.589505 (rank : 4)	θ value	1.47631e-18 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

LY10_HUMAN
NC score	0.578708 (rank : 5)	θ value	5.42112e-21 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SP100_HUMAN
NC score	0.572754 (rank : 6)	θ value	9.81109e-47 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

DEAF1_HUMAN
NC score	0.310519 (rank : 7)	θ value	0.000461057 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
NC score	0.308028 (rank : 8)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

HMG1X_HUMAN
NC score	0.104673 (rank : 9)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	32	Target Neighborhood Hits	97	Shared Neighborhood Hits	1
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

GMEB1_MOUSE
NC score	0.103968 (rank : 10)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB2_HUMAN
NC score	0.103435 (rank : 11)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
NC score	0.103396 (rank : 12)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	32	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

GMEB1_HUMAN
NC score	0.103322 (rank : 13)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

HMGB1_MOUSE
NC score	0.100089 (rank : 14)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	32	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_HUMAN
NC score	0.100075 (rank : 15)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	32	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

AIRE_HUMAN
NC score	0.095790 (rank : 16)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.094847 (rank : 17)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

HMGB2_MOUSE
NC score	0.094136 (rank : 18)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	32	Target Neighborhood Hits	111	Shared Neighborhood Hits	1
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_HUMAN
NC score	0.093403 (rank : 19)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	32	Target Neighborhood Hits	114	Shared Neighborhood Hits	1
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_MOUSE
NC score	0.082548 (rank : 20)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	32	Target Neighborhood Hits	88	Shared Neighborhood Hits	1
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_HUMAN
NC score	0.082168 (rank : 21)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	32	Target Neighborhood Hits	86	Shared Neighborhood Hits	1
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

DSPP_HUMAN
NC score	0.045076 (rank : 22)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	645	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

JHD2C_HUMAN
NC score	0.040011 (rank : 23)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	279	Shared Neighborhood Hits	6
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

JHD2C_MOUSE
NC score	0.038442 (rank : 24)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

SFRIP_HUMAN
NC score	0.034250 (rank : 25)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	530	Shared Neighborhood Hits	9
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

LETM1_HUMAN
NC score	0.026136 (rank : 26)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	338	Shared Neighborhood Hits	3
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

TBCD5_HUMAN
NC score	0.025257 (rank : 27)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

PROX1_HUMAN
NC score	0.023866 (rank : 28)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

SRRM2_HUMAN
NC score	0.022607 (rank : 29)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	1296	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RHG12_HUMAN
NC score	0.019048 (rank : 30)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CA106_HUMAN
NC score	0.019005 (rank : 31)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

SRRM2_MOUSE
NC score	0.018032 (rank : 32)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	1470	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BOP1_MOUSE
NC score	0.016921 (rank : 33)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	267	Shared Neighborhood Hits	2
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

RPGF2_HUMAN
NC score	0.016877 (rank : 34)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

AP3B1_MOUSE
NC score	0.014654 (rank : 35)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

NFAC3_HUMAN
NC score	0.013078 (rank : 36)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

CTR9_HUMAN
NC score	0.013051 (rank : 37)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	383	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

PCLO_HUMAN
NC score	0.011684 (rank : 38)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	2046	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TACC3_MOUSE
NC score	0.011173 (rank : 39)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	607	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

USH1C_MOUSE
NC score	0.007954 (rank : 40)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	557	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

CD2L5_HUMAN
NC score	0.005928 (rank : 41)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	987	Shared Neighborhood Hits	5
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

ITCH_MOUSE
NC score	0.005853 (rank : 42)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

PCDGH_HUMAN
NC score	0.005039 (rank : 43)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	164	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5G0, Q9Y5C6	Gene names	PCDHGB5
Domain Architecture
Description	Protocadherin gamma B5 precursor (PCDH-gamma-B5).

MARK4_MOUSE
NC score	0.001228 (rank : 44)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	898	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).