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Network neighborhood for query Sequence : SP110_HUMAN

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SP110_HUMAN
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SP110_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

IPR1_MOUSE
θ value	2.92676e-75 (rank : 2)	NC score	0.765024 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

LY10_HUMAN
θ value	2.3998e-69 (rank : 3)	NC score	0.874152 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	69
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SP100_HUMAN
θ value	2.12685e-25 (rank : 4)	NC score	0.456081 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SP100_MOUSE
θ value	1.47631e-18 (rank : 5)	NC score	0.589505 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

S100R_MOUSE
θ value	3.28887e-18 (rank : 6)	NC score	0.609300 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

AIRE_MOUSE
θ value	3.76295e-14 (rank : 7)	NC score	0.565595 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	196	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TIF1A_MOUSE
θ value	3.76295e-14 (rank : 8)	NC score	0.455455 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
θ value	7.09661e-13 (rank : 9)	NC score	0.446641 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	327	Shared Neighborhood Hits	62
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

AIRE_HUMAN
θ value	4.59992e-12 (rank : 10)	NC score	0.559120 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	58
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

TRI66_HUMAN
θ value	1.02475e-11 (rank : 11)	NC score	0.466433 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	479	Shared Neighborhood Hits	69
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	8.67504e-11 (rank : 12)	NC score	0.464748 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1G_MOUSE
θ value	4.30538e-10 (rank : 13)	NC score	0.419784 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	498	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
θ value	6.21693e-09 (rank : 14)	NC score	0.418882 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	410	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

DEAF1_HUMAN
θ value	7.59969e-07 (rank : 15)	NC score	0.356844 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
θ value	7.59969e-07 (rank : 16)	NC score	0.356428 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

PHF12_HUMAN
θ value	9.92553e-07 (rank : 17)	NC score	0.436967 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	54
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	9.92553e-07 (rank : 18)	NC score	0.437229 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	172	Shared Neighborhood Hits	55
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CHD4_HUMAN
θ value	1.29631e-06 (rank : 19)	NC score	0.272104 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	365	Shared Neighborhood Hits	67
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	1.29631e-06 (rank : 20)	NC score	0.271262 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	408	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	1.29631e-06 (rank : 21)	NC score	0.275329 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	349	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
θ value	4.92598e-06 (rank : 22)	NC score	0.266894 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	397	Shared Neighborhood Hits	73
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

PF21A_HUMAN
θ value	8.40245e-06 (rank : 23)	NC score	0.428730 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	303	Shared Neighborhood Hits	65
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	8.40245e-06 (rank : 24)	NC score	0.435090 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	285	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

BPTF_HUMAN
θ value	1.43324e-05 (rank : 25)	NC score	0.313510 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	786	Shared Neighborhood Hits	84
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

GMEB1_HUMAN
θ value	1.87187e-05 (rank : 26)	NC score	0.280093 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

GMEB1_MOUSE
θ value	2.44474e-05 (rank : 27)	NC score	0.280222 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB2_HUMAN
θ value	0.000270298 (rank : 28)	NC score	0.273675 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
θ value	0.000270298 (rank : 29)	NC score	0.273446 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

NSD1_HUMAN
θ value	0.000270298 (rank : 30)	NC score	0.289575 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	427	Shared Neighborhood Hits	70
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0.000270298 (rank : 31)	NC score	0.291635 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	472	Shared Neighborhood Hits	72
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21B_HUMAN
θ value	0.000270298 (rank : 32)	NC score	0.398120 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TIF1B_HUMAN
θ value	0.000602161 (rank : 33)	NC score	0.377877 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	312	Shared Neighborhood Hits	53
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	0.000602161 (rank : 34)	NC score	0.380146 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	276	Shared Neighborhood Hits	53
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

PHF22_MOUSE
θ value	0.00228821 (rank : 35)	NC score	0.236402 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_HUMAN
θ value	0.00390308 (rank : 36)	NC score	0.232956 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PKCB1_HUMAN
θ value	0.00665767 (rank : 37)	NC score	0.342201 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	488	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_MOUSE
θ value	0.00869519 (rank : 38)	NC score	0.362608 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	60
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MYST4_HUMAN
θ value	0.0148317 (rank : 39)	NC score	0.213366 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	0.0148317 (rank : 40)	NC score	0.216358 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SOX6_MOUSE
θ value	0.0148317 (rank : 41)	NC score	0.052995 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

MLL3_HUMAN
θ value	0.0193708 (rank : 42)	NC score	0.187938 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	1644	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SFR11_HUMAN
θ value	0.0193708 (rank : 43)	NC score	0.109428 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

TARA_MOUSE
θ value	0.0193708 (rank : 44)	NC score	0.058593 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	1133	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

JAD1D_HUMAN
θ value	0.0252991 (rank : 45)	NC score	0.182583 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MLL2_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.190126 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	1788	Shared Neighborhood Hits	82
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
θ value	0.0330416 (rank : 47)	NC score	0.198615 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	1399	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SOX6_HUMAN
θ value	0.0330416 (rank : 48)	NC score	0.050701 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	332	Shared Neighborhood Hits	17
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

PHF1_HUMAN
θ value	0.0431538 (rank : 49)	NC score	0.184564 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	40
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	0.0431538 (rank : 50)	NC score	0.180998 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

ZN655_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.002253 (rank : 253)
Query Neighborhood Hits	141	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N720, Q8IV00, Q8TA89, Q96EZ3	Gene names	ZNF655, VIK
Domain Architecture	No domain graphic available
Description	Zinc finger protein 655 (Vav-interacting Krueppel-like protein).

ABTAP_MOUSE
θ value	0.0563607 (rank : 52)	NC score	0.053198 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ATRX_MOUSE
θ value	0.0563607 (rank : 53)	NC score	0.161575 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	682	Shared Neighborhood Hits	67
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
θ value	0.0736092 (rank : 54)	NC score	0.152837 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	842	Shared Neighborhood Hits	71
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

JAD1D_MOUSE
θ value	0.125558 (rank : 55)	NC score	0.177391 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	228	Shared Neighborhood Hits	47
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

TSH1_MOUSE
θ value	0.125558 (rank : 56)	NC score	0.032068 (rank : 223)
Query Neighborhood Hits	141	Target Neighborhood Hits	675	Shared Neighborhood Hits	27
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

GON4L_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.049737 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

BAZ2A_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.246701 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	780	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MPP8_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.043498 (rank : 216)
Query Neighborhood Hits	141	Target Neighborhood Hits	948	Shared Neighborhood Hits	47
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYST3_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.203756 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	772	Shared Neighborhood Hits	74
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.206310 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	688	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PPIG_HUMAN
θ value	0.21417 (rank : 62)	NC score	0.036214 (rank : 222)
Query Neighborhood Hits	141	Target Neighborhood Hits	670	Shared Neighborhood Hits	40
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SFRS4_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.038051 (rank : 220)
Query Neighborhood Hits	141	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SRRM2_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.074648 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	1296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RSF1_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.230813 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	539	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SFR16_MOUSE
θ value	0.47712 (rank : 66)	NC score	0.050120 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

TINF2_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.045881 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG9	Gene names	Tinf2, Tin2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

DNM3B_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.082512 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DPF1_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.206260 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

PCLO_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.050492 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	2046	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ZMY11_MOUSE
θ value	0.62314 (rank : 71)	NC score	0.252042 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

DDX46_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.019862 (rank : 232)
Query Neighborhood Hits	141	Target Neighborhood Hits	357	Shared Neighborhood Hits	19
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	0.813845 (rank : 73)	NC score	0.019882 (rank : 231)
Query Neighborhood Hits	141	Target Neighborhood Hits	358	Shared Neighborhood Hits	21
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

Z3H7A_HUMAN
θ value	0.813845 (rank : 74)	NC score	0.031079 (rank : 224)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

ZMY11_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.254687 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

CBP_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.102070 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	1051	Shared Neighborhood Hits	56
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CJ012_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.062795 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	467	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

DNM3B_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.072355 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

FA13A_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.021946 (rank : 230)
Query Neighborhood Hits	141	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

NIPBL_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.078775 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	1311	Shared Neighborhood Hits	73
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TP53B_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.059418 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	644	Shared Neighborhood Hits	49
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BAZ2A_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.241783 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	744	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

SRRM2_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.069772 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	1470	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

UNC5B_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.008984 (rank : 246)
Query Neighborhood Hits	141	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

CHD9_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.090244 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CIR_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.051360 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

DNM3A_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.069071 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.068632 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DPF1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.213643 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

NCOA6_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.050895 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	1076	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ZN75A_HUMAN
θ value	2.36792 (rank : 91)	NC score	-0.001539 (rank : 256)
Query Neighborhood Hits	141	Target Neighborhood Hits	720	Shared Neighborhood Hits	5
SwissProt Accessions	Q96N20, Q92669	Gene names	ZNF75A
Domain Architecture	No domain graphic available
Description	Zinc finger protein 75A.

APC_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.028784 (rank : 225)
Query Neighborhood Hits	141	Target Neighborhood Hits	603	Shared Neighborhood Hits	34
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CHD9_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.091894 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

H2BWT_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.012383 (rank : 243)
Query Neighborhood Hits	141	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2G1	Gene names	H2BFWT
Domain Architecture	No domain graphic available
Description	Histone H2B type W-T (H2B histone family member W testis-specific).

LPIN2_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.015437 (rank : 239)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

MDC1_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.059782 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	1446	Shared Neighborhood Hits	69
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PML_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.117784 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	248	Shared Neighborhood Hits	19
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

SRRM1_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.057573 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	966	Shared Neighborhood Hits	53
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRDN_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.039708 (rank : 219)
Query Neighborhood Hits	141	Target Neighborhood Hits	542	Shared Neighborhood Hits	33
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

AP3B2_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.017673 (rank : 235)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

ARHGF_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.019687 (rank : 233)
Query Neighborhood Hits	141	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

K1688_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.017177 (rank : 236)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

PHF20_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.061068 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PRP4B_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.004848 (rank : 249)
Query Neighborhood Hits	141	Target Neighborhood Hits	1040	Shared Neighborhood Hits	28
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TARA_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.060340 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	1626	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TOP2A_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.016086 (rank : 237)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

CNGB3_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.010107 (rank : 245)
Query Neighborhood Hits	141	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

NCOR1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.022001 (rank : 229)
Query Neighborhood Hits	141	Target Neighborhood Hits	577	Shared Neighborhood Hits	32
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

PHF14_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.151616 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	447	Shared Neighborhood Hits	62
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.152659 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	342	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

REQU_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.198811 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	519	Shared Neighborhood Hits	56
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

TXND2_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.054840 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	828	Shared Neighborhood Hits	59
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

YTDC1_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.044679 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	458	Shared Neighborhood Hits	34
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

BRD1_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.117417 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	49
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

CDKL3_MOUSE
θ value	6.88961 (rank : 115)	NC score	-0.004140 (rank : 258)
Query Neighborhood Hits	141	Target Neighborhood Hits	857	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

EP15_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.003540 (rank : 251)
Query Neighborhood Hits	141	Target Neighborhood Hits	1021	Shared Neighborhood Hits	18
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

K1045_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.040908 (rank : 218)
Query Neighborhood Hits	141	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TL4, Q8BH08	Gene names	Kiaa1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

KI67_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.055204 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	581	Shared Neighborhood Hits	47
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LHX61_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.002980 (rank : 252)
Query Neighborhood Hits	141	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

MINT_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.041630 (rank : 217)
Query Neighborhood Hits	141	Target Neighborhood Hits	1291	Shared Neighborhood Hits	67
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MTR1L_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.000417 (rank : 255)
Query Neighborhood Hits	141	Target Neighborhood Hits	1180	Shared Neighborhood Hits	19
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

MYO9B_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.015574 (rank : 238)
Query Neighborhood Hits	141	Target Neighborhood Hits	641	Shared Neighborhood Hits	36
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

REQU_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.199522 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	523	Shared Neighborhood Hits	58
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SELPL_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.046232 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	588	Shared Neighborhood Hits	35
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SETX_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.024528 (rank : 227)
Query Neighborhood Hits	141	Target Neighborhood Hits	368	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SRR35_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.013339 (rank : 242)
Query Neighborhood Hits	141	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

ZCH11_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.024193 (rank : 228)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

AP3B2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.018614 (rank : 234)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

ARI4A_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.037308 (rank : 221)
Query Neighborhood Hits	141	Target Neighborhood Hits	434	Shared Neighborhood Hits	33
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ARRD1_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.012350 (rank : 244)
Query Neighborhood Hits	141	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CEP57_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.006517 (rank : 248)
Query Neighborhood Hits	141	Target Neighborhood Hits	580	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

EP300_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.097515 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

JAD1A_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.166202 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	328	Shared Neighborhood Hits	56
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

MFN1_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.007927 (rank : 247)
Query Neighborhood Hits	141	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

MYH3_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.004365 (rank : 250)
Query Neighborhood Hits	141	Target Neighborhood Hits	1660	Shared Neighborhood Hits	41
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

SON_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.053373 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	1568	Shared Neighborhood Hits	57
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPEG_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.001574 (rank : 254)
Query Neighborhood Hits	141	Target Neighborhood Hits	1959	Shared Neighborhood Hits	41
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TAF9_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.014150 (rank : 240)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TCOF_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.027790 (rank : 226)
Query Neighborhood Hits	141	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TXLNB_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.013978 (rank : 241)
Query Neighborhood Hits	141	Target Neighborhood Hits	912	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ZN667_MOUSE
θ value	8.99809 (rank : 141)	NC score	-0.002641 (rank : 257)
Query Neighborhood Hits	141	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q2TL60	Gene names	Znf667, Mip1, Zfp667
Domain Architecture	No domain graphic available
Description	Zinc finger protein 667 (Myocardial ischemic preconditioning up- regulated protein 1).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.216464 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.196498 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	701	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.209426 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	394	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.207803 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	803	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD2_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.104624 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.098009 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	369	Shared Neighborhood Hits	31
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.098013 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	402	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.101152 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	851	Shared Neighborhood Hits	49
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.101482 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD7_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.058060 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.056875 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.077596 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.083190 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	422	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD9_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.052282 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.060834 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRDT_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.094839 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.091883 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	243	Shared Neighborhood Hits	23
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BRPF1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.125846 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRPF3_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.118191 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	217	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BRWD1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.051429 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	478	Shared Neighborhood Hits	31
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BTAF1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.066185 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CBP_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.091125 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	941	Shared Neighborhood Hits	48
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.110802 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.084071 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.082714 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.086948 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	360	Shared Neighborhood Hits	26
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.086693 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	342	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.083641 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	235	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

DNM3L_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.061670 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.082290 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

EP400_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.070799 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	556	Shared Neighborhood Hits	33
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.072859 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ERCC6_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.076904 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

GCNL2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.091087 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	159	Shared Neighborhood Hits	17
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.087490 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

HMG1X_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.061262 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.060286 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.059706 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.057837 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.058563 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.051252 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HRX_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.106024 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	825	Shared Neighborhood Hits	74
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ING1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.054540 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.053506 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.066772 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

ING2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.068778 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.052397 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING5_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.070212 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.068003 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

INOC1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.068571 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.068975 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

IWS1_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.052226 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	1241	Shared Neighborhood Hits	62
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.061008 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	1258	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAD1C_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.167705 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	187	Shared Neighborhood Hits	48
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.168408 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	164	Shared Neighborhood Hits	50
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JADE1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.094152 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.094069 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	160	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.096701 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	199	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.095454 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	560	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.088509 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	48
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.091515 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	50
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

MLL4_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.101428 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	722	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MTF2_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.115929 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.115106 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

NPBL_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.062378 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	1041	Shared Neighborhood Hits	63
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PB1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.085331 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	261	Shared Neighborhood Hits	24
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCAF_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.089970 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PHF10_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.163704 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.162171 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PML_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.108720 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RA54B_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.071266 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.071205 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.073735 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.072371 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

SET1A_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.058997 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	690	Shared Neighborhood Hits	41
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD2_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.053480 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMAL1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.065506 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.066201 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.075889 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.076030 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.098948 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	503	Shared Neighborhood Hits	35
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.098749 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	597	Shared Neighborhood Hits	38
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA5_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.075577 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.075564 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRA3_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.053244 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	265	Shared Neighborhood Hits	10
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.055219 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRCD_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.070844 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.071001 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

TAF1L_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.084057 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.089743 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TAF3_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.064531 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	568	Shared Neighborhood Hits	60
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.059364 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	463	Shared Neighborhood Hits	51
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TGON2_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.051208 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	1037	Shared Neighborhood Hits	55
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRI29_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.050744 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	273	Shared Neighborhood Hits	13
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI36_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.058065 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	282	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.054034 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI42_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.063531 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	283	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.066073 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI45_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.131585 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.130124 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.055846 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.054401 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI56_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.084685 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	339	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.085694 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI63_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.052737 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	298	Shared Neighborhood Hits	13
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.052664 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.052931 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	361	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM2_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.072338 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	330	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.072239 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.069827 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	357	Shared Neighborhood Hits	10
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.071613 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TTF2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.051319 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.063227 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	364	Shared Neighborhood Hits	32
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

UHRF1_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.150985 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	272	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.144988 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.121878 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	269	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.121584 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	275	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

Hits sorted by NC score

SP110_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

LY10_HUMAN
NC score	0.874152 (rank : 2)	θ value	2.3998e-69 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	69
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

IPR1_MOUSE
NC score	0.765024 (rank : 3)	θ value	2.92676e-75 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

S100R_MOUSE
NC score	0.609300 (rank : 4)	θ value	3.28887e-18 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

SP100_MOUSE
NC score	0.589505 (rank : 5)	θ value	1.47631e-18 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

AIRE_MOUSE
NC score	0.565595 (rank : 6)	θ value	3.76295e-14 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	196	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.559120 (rank : 7)	θ value	4.59992e-12 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	58
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

TRI66_HUMAN
NC score	0.466433 (rank : 8)	θ value	1.02475e-11 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	479	Shared Neighborhood Hits	69
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
NC score	0.464748 (rank : 9)	θ value	8.67504e-11 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SP100_HUMAN
NC score	0.456081 (rank : 10)	θ value	2.12685e-25 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

TIF1A_MOUSE
NC score	0.455455 (rank : 11)	θ value	3.76295e-14 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.446641 (rank : 12)	θ value	7.09661e-13 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	327	Shared Neighborhood Hits	62
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

PHF12_MOUSE
NC score	0.437229 (rank : 13)	θ value	9.92553e-07 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	172	Shared Neighborhood Hits	55
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.436967 (rank : 14)	θ value	9.92553e-07 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	54
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21A_MOUSE
NC score	0.435090 (rank : 15)	θ value	8.40245e-06 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	285	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.428730 (rank : 16)	θ value	8.40245e-06 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	303	Shared Neighborhood Hits	65
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TIF1G_MOUSE
NC score	0.419784 (rank : 17)	θ value	4.30538e-10 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	498	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.418882 (rank : 18)	θ value	6.21693e-09 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	410	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

PF21B_HUMAN
NC score	0.398120 (rank : 19)	θ value	0.000270298 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TIF1B_MOUSE
NC score	0.380146 (rank : 20)	θ value	0.000602161 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	276	Shared Neighborhood Hits	53
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1B_HUMAN
NC score	0.377877 (rank : 21)	θ value	0.000602161 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	312	Shared Neighborhood Hits	53
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PF21B_MOUSE
NC score	0.362608 (rank : 22)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	60
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

DEAF1_HUMAN
NC score	0.356844 (rank : 23)	θ value	7.59969e-07 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
NC score	0.356428 (rank : 24)	θ value	7.59969e-07 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

PKCB1_HUMAN
NC score	0.342201 (rank : 25)	θ value	0.00665767 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	488	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BPTF_HUMAN
NC score	0.313510 (rank : 26)	θ value	1.43324e-05 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	786	Shared Neighborhood Hits	84
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NSD1_MOUSE
NC score	0.291635 (rank : 27)	θ value	0.000270298 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	472	Shared Neighborhood Hits	72
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.289575 (rank : 28)	θ value	0.000270298 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	427	Shared Neighborhood Hits	70
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

GMEB1_MOUSE
NC score	0.280222 (rank : 29)	θ value	2.44474e-05 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB1_HUMAN
NC score	0.280093 (rank : 30)	θ value	1.87187e-05 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

CHD5_HUMAN
NC score	0.275329 (rank : 31)	θ value	1.29631e-06 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	349	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

GMEB2_HUMAN
NC score	0.273675 (rank : 32)	θ value	0.000270298 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
NC score	0.273446 (rank : 33)	θ value	0.000270298 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

CHD4_HUMAN
NC score	0.272104 (rank : 34)	θ value	1.29631e-06 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	365	Shared Neighborhood Hits	67
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.271262 (rank : 35)	θ value	1.29631e-06 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	408	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.266894 (rank : 36)	θ value	4.92598e-06 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	397	Shared Neighborhood Hits	73
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ZMY11_HUMAN
NC score	0.254687 (rank : 37)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
NC score	0.252042 (rank : 38)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BAZ2A_HUMAN
NC score	0.246701 (rank : 39)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	780	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
NC score	0.241783 (rank : 40)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	744	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PHF22_MOUSE
NC score	0.236402 (rank : 41)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_HUMAN
NC score	0.232956 (rank : 42)	θ value	0.00390308 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

RSF1_HUMAN
NC score	0.230813 (rank : 43)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	539	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BAZ1A_HUMAN
NC score	0.216464 (rank : 44)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

MYST4_MOUSE
NC score	0.216358 (rank : 45)	θ value	0.0148317 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

DPF1_HUMAN
NC score	0.213643 (rank : 46)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MYST4_HUMAN
NC score	0.213366 (rank : 47)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

BAZ1B_MOUSE
NC score	0.209426 (rank : 48)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	394	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2B_HUMAN
NC score	0.207803 (rank : 49)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	803	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MYST3_MOUSE
NC score	0.206310 (rank : 50)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	688	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

DPF1_MOUSE
NC score	0.206260 (rank : 51)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MYST3_HUMAN
NC score	0.203756 (rank : 52)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	772	Shared Neighborhood Hits	74
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

REQU_HUMAN
NC score	0.199522 (rank : 53)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	523	Shared Neighborhood Hits	58
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.198811 (rank : 54)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	519	Shared Neighborhood Hits	56
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

MLL3_MOUSE
NC score	0.198615 (rank : 55)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	1399	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BAZ1B_HUMAN
NC score	0.196498 (rank : 56)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	701	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

MLL2_HUMAN
NC score	0.190126 (rank : 57)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	1788	Shared Neighborhood Hits	82
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.187938 (rank : 58)	θ value	0.0193708 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	1644	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PHF1_HUMAN
NC score	0.184564 (rank : 59)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	40
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

JAD1D_HUMAN
NC score	0.182583 (rank : 60)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	147	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PHF1_MOUSE
NC score	0.180998 (rank : 61)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

JAD1D_MOUSE
NC score	0.177391 (rank : 62)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	228	Shared Neighborhood Hits	47
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_MOUSE
NC score	0.168408 (rank : 63)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	164	Shared Neighborhood Hits	50
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.167705 (rank : 64)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	187	Shared Neighborhood Hits	48
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1A_HUMAN
NC score	0.166202 (rank : 65)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	328	Shared Neighborhood Hits	56
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

PHF10_HUMAN
NC score	0.163704 (rank : 66)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.162171 (rank : 67)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

ATRX_MOUSE
NC score	0.161575 (rank : 68)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	682	Shared Neighborhood Hits	67
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.152837 (rank : 69)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	842	Shared Neighborhood Hits	71
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

PHF14_MOUSE
NC score	0.152659 (rank : 70)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	342	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.151616 (rank : 71)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	447	Shared Neighborhood Hits	62
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

UHRF1_HUMAN
NC score	0.150985 (rank : 72)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	141	Target Neighborhood Hits	272	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
NC score	0.144988 (rank : 73)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

TRI45_HUMAN
NC score	0.131585 (rank : 74)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	141	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
NC score	0.130124 (rank : 75)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	141	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

BRPF1_HUMAN
NC score	0.125846 (rank : 76)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

UHRF2_HUMAN
NC score	0.121878 (rank : 77)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	141	Target Neighborhood Hits	269	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.121584 (rank : 78)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	141	Target Neighborhood Hits	275	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BRPF3_HUMAN
NC score	0.118191 (rank : 79)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	217	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

PML_HUMAN
NC score	0.117784 (rank : 80)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	248	Shared Neighborhood Hits	19
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

BRD1_HUMAN
NC score	0.117417 (rank : 81)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	49
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

MTF2_HUMAN
NC score	0.115929 (rank : 82)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.115106 (rank : 83)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

CECR2_HUMAN
NC score	0.110802 (rank : 84)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

SFR11_HUMAN
NC score	0.109428 (rank : 85)	θ value	0.0193708 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

PML_MOUSE
NC score	0.108720 (rank : 86)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

HRX_HUMAN
NC score	0.106024 (rank : 87)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	825	Shared Neighborhood Hits	74
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

BRD2_HUMAN
NC score	0.104624 (rank : 88)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CBP_MOUSE
NC score	0.102070 (rank : 89)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	1051	Shared Neighborhood Hits	56
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BRD4_MOUSE
NC score	0.101482 (rank : 90)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MLL4_HUMAN
NC score	0.101428 (rank : 91)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	722	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

BRD4_HUMAN
NC score	0.101152 (rank : 92)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	851	Shared Neighborhood Hits	49
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

SMCA2_HUMAN
NC score	0.098948 (rank : 93)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	141	Target Neighborhood Hits	503	Shared Neighborhood Hits	35
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.098749 (rank : 94)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	141	Target Neighborhood Hits	597	Shared Neighborhood Hits	38
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

BRD3_MOUSE
NC score	0.098013 (rank : 95)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	402	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD3_HUMAN
NC score	0.098009 (rank : 96)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	369	Shared Neighborhood Hits	31
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

EP300_HUMAN
NC score	0.097515 (rank : 97)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

JADE2_HUMAN
NC score	0.096701 (rank : 98)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	199	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
NC score	0.095454 (rank : 99)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	560	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BRDT_HUMAN
NC score	0.094839 (rank : 100)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

JADE1_HUMAN
NC score	0.094152 (rank : 101)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.094069 (rank : 102)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	160	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

CHD9_MOUSE
NC score	0.091894 (rank : 103)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

BRDT_MOUSE
NC score	0.091883 (rank : 104)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	243	Shared Neighborhood Hits	23
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

JADE3_MOUSE
NC score	0.091515 (rank : 105)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	50
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

CBP_HUMAN
NC score	0.091125 (rank : 106)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	941	Shared Neighborhood Hits	48
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GCNL2_HUMAN
NC score	0.091087 (rank : 107)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	159	Shared Neighborhood Hits	17
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

CHD9_HUMAN
NC score	0.090244 (rank : 108)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

PCAF_HUMAN
NC score	0.089970 (rank : 109)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

TAF1_HUMAN
NC score	0.089743 (rank : 110)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

JADE3_HUMAN
NC score	0.088509 (rank : 111)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	48
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

GCNL2_MOUSE
NC score	0.087490 (rank : 112)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

CHD2_HUMAN
NC score	0.086948 (rank : 113)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	360	Shared Neighborhood Hits	26
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
NC score	0.086693 (rank : 114)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	342	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

TRI56_MOUSE
NC score	0.085694 (rank : 115)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	141	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

PB1_HUMAN
NC score	0.085331 (rank : 116)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	261	Shared Neighborhood Hits	24
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TRI56_HUMAN
NC score	0.084685 (rank : 117)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	141	Target Neighborhood Hits	339	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

CHD1_HUMAN
NC score	0.084071 (rank : 118)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

TAF1L_HUMAN
NC score	0.084057 (rank : 119)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

CHD8_HUMAN
NC score	0.083641 (rank : 120)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	235	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

BRD8_MOUSE
NC score	0.083190 (rank : 121)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	422	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CHD1_MOUSE
NC score	0.082714 (rank : 122)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

DNM3B_HUMAN
NC score	0.082512 (rank : 123)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3L_MOUSE
NC score	0.082290 (rank : 124)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

NIPBL_HUMAN
NC score	0.078775 (rank : 125)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	1311	Shared Neighborhood Hits	73
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

BRD8_HUMAN
NC score	0.077596 (rank : 126)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

ERCC6_HUMAN
NC score	0.076904 (rank : 127)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA1_MOUSE
NC score	0.076030 (rank : 128)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA1_HUMAN
NC score	0.075889 (rank : 129)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_HUMAN
NC score	0.075577 (rank : 130)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	141	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
NC score	0.075564 (rank : 131)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	141	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SRRM2_HUMAN
NC score	0.074648 (rank : 132)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	1296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RAD54_HUMAN
NC score	0.073735 (rank : 133)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

EP400_MOUSE
NC score	0.072859 (rank : 134)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RAD54_MOUSE
NC score	0.072371 (rank : 135)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

DNM3B_MOUSE
NC score	0.072355 (rank : 136)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

TRIM2_HUMAN
NC score	0.072338 (rank : 137)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	141	Target Neighborhood Hits	330	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.072239 (rank : 138)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	141	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_MOUSE
NC score	0.071613 (rank : 139)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	141	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RA54B_HUMAN
NC score	0.071266 (rank : 140)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
NC score	0.071205 (rank : 141)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMRCD_MOUSE
NC score	0.071001 (rank : 142)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.070844 (rank : 143)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

EP400_HUMAN
NC score	0.070799 (rank : 144)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	556	Shared Neighborhood Hits	33
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ING5_HUMAN
NC score	0.070212 (rank : 145)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

TRIM3_HUMAN
NC score	0.069827 (rank : 146)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	141	Target Neighborhood Hits	357	Shared Neighborhood Hits	10
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

SRRM2_MOUSE
NC score	0.069772 (rank : 147)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	1470	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DNM3A_HUMAN
NC score	0.069071 (rank : 148)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

INOC1_MOUSE
NC score	0.068975 (rank : 149)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

ING2_MOUSE
NC score	0.068778 (rank : 150)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

DNM3A_MOUSE
NC score	0.068632 (rank : 151)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

INOC1_HUMAN
NC score	0.068571 (rank : 152)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

ING5_MOUSE
NC score	0.068003 (rank : 153)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

ING2_HUMAN
NC score	0.066772 (rank : 154)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

SMAL1_MOUSE
NC score	0.066201 (rank : 155)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

BTAF1_HUMAN
NC score	0.066185 (rank : 156)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

TRI42_MOUSE
NC score	0.066073 (rank : 157)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	141	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

SMAL1_HUMAN
NC score	0.065506 (rank : 158)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

TAF3_HUMAN
NC score	0.064531 (rank : 159)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	141	Target Neighborhood Hits	568	Shared Neighborhood Hits	60
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI42_HUMAN
NC score	0.063531 (rank : 160)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	141	Target Neighborhood Hits	283	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TTF2_MOUSE
NC score	0.063227 (rank : 161)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	141	Target Neighborhood Hits	364	Shared Neighborhood Hits	32
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

CJ012_HUMAN
NC score	0.062795 (rank : 162)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	467	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

NPBL_MOUSE
NC score	0.062378 (rank : 163)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	1041	Shared Neighborhood Hits	63
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

DNM3L_HUMAN
NC score	0.061670 (rank : 164)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

HMG1X_HUMAN
NC score	0.061262 (rank : 165)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

PHF20_MOUSE
NC score	0.061068 (rank : 166)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

IWS1_MOUSE
NC score	0.061008 (rank : 167)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	1258	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BRD9_MOUSE
NC score	0.060834 (rank : 168)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

TARA_HUMAN
NC score	0.060340 (rank : 169)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	1626	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

HMGB1_HUMAN
NC score	0.060286 (rank : 170)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

MDC1_HUMAN
NC score	0.059782 (rank : 171)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	1446	Shared Neighborhood Hits	69
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

HMGB1_MOUSE
NC score	0.059706 (rank : 172)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

TP53B_MOUSE
NC score	0.059418 (rank : 173)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	644	Shared Neighborhood Hits	49
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TAF3_MOUSE
NC score	0.059364 (rank : 174)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	141	Target Neighborhood Hits	463	Shared Neighborhood Hits	51
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SET1A_HUMAN
NC score	0.058997 (rank : 175)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	141	Target Neighborhood Hits	690	Shared Neighborhood Hits	41
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TARA_MOUSE
NC score	0.058593 (rank : 176)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	1133	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

HMGB2_MOUSE
NC score	0.058563 (rank : 177)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

TRI36_HUMAN
NC score	0.058065 (rank : 178)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	141	Target Neighborhood Hits	282	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

BRD7_HUMAN
NC score	0.058060 (rank : 179)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

HMGB2_HUMAN
NC score	0.057837 (rank : 180)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

SRRM1_MOUSE
NC score	0.057573 (rank : 181)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	966	Shared Neighborhood Hits	53
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BRD7_MOUSE
NC score	0.056875 (rank : 182)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

TRI46_HUMAN
NC score	0.055846 (rank : 183)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	141	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

SMRA3_MOUSE
NC score	0.055219 (rank : 184)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	141	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

KI67_HUMAN
NC score	0.055204 (rank : 185)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	581	Shared Neighborhood Hits	47
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

TXND2_MOUSE
NC score	0.054840 (rank : 186)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	828	Shared Neighborhood Hits	59
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ING1_HUMAN
NC score	0.054540 (rank : 187)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

TRI46_MOUSE
NC score	0.054401 (rank : 188)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	141	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI36_MOUSE
NC score	0.054034 (rank : 189)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	141	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

ING1_MOUSE
NC score	0.053506 (rank : 190)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

SETD2_HUMAN
NC score	0.053480 (rank : 191)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	141	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SON_HUMAN
NC score	0.053373 (rank : 192)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	1568	Shared Neighborhood Hits	57
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SMRA3_HUMAN
NC score	0.053244 (rank : 193)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	141	Target Neighborhood Hits	265	Shared Neighborhood Hits	10
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ABTAP_MOUSE
NC score	0.053198 (rank : 194)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

SOX6_MOUSE
NC score	0.052995 (rank : 195)	θ value	0.0148317 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

TRIM1_MOUSE
NC score	0.052931 (rank : 196)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	141	Target Neighborhood Hits	361	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI63_HUMAN
NC score	0.052737 (rank : 197)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	141	Target Neighborhood Hits	298	Shared Neighborhood Hits	13
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM1_HUMAN
NC score	0.052664 (rank : 198)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	141	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

ING3_HUMAN
NC score	0.052397 (rank : 199)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

BRD9_HUMAN
NC score	0.052282 (rank : 200)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

IWS1_HUMAN
NC score	0.052226 (rank : 201)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	1241	Shared Neighborhood Hits	62
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BRWD1_MOUSE
NC score	0.051429 (rank : 202)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	478	Shared Neighborhood Hits	31
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CIR_MOUSE
NC score	0.051360 (rank : 203)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

TTF2_HUMAN
NC score	0.051319 (rank : 204)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	141	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

HMGB3_MOUSE
NC score	0.051252 (rank : 205)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

TGON2_HUMAN
NC score	0.051208 (rank : 206)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	141	Target Neighborhood Hits	1037	Shared Neighborhood Hits	55
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

NCOA6_MOUSE
NC score	0.050895 (rank : 207)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	1076	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TRI29_HUMAN
NC score	0.050744 (rank : 208)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	141	Target Neighborhood Hits	273	Shared Neighborhood Hits	13
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

SOX6_HUMAN
NC score	0.050701 (rank : 209)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	332	Shared Neighborhood Hits	17
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

PCLO_HUMAN
NC score	0.050492 (rank : 210)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	2046	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SFR16_MOUSE
NC score	0.050120 (rank : 211)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

GON4L_MOUSE
NC score	0.049737 (rank : 212)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SELPL_MOUSE
NC score	0.046232 (rank : 213)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	588	Shared Neighborhood Hits	35
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TINF2_MOUSE
NC score	0.045881 (rank : 214)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG9	Gene names	Tinf2, Tin2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

YTDC1_HUMAN
NC score	0.044679 (rank : 215)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	458	Shared Neighborhood Hits	34
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

MPP8_HUMAN
NC score	0.043498 (rank : 216)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	948	Shared Neighborhood Hits	47
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MINT_HUMAN
NC score	0.041630 (rank : 217)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	1291	Shared Neighborhood Hits	67
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

K1045_MOUSE
NC score	0.040908 (rank : 218)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TL4, Q8BH08	Gene names	Kiaa1045
Domain Architecture	No domain graphic available
Description	Protein KIAA1045.

TRDN_HUMAN
NC score	0.039708 (rank : 219)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	542	Shared Neighborhood Hits	33
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

SFRS4_HUMAN
NC score	0.038051 (rank : 220)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

ARI4A_HUMAN
NC score	0.037308 (rank : 221)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	434	Shared Neighborhood Hits	33
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

PPIG_HUMAN
NC score	0.036214 (rank : 222)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	670	Shared Neighborhood Hits	40
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TSH1_MOUSE
NC score	0.032068 (rank : 223)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	675	Shared Neighborhood Hits	27
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

Z3H7A_HUMAN
NC score	0.031079 (rank : 224)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

APC_HUMAN
NC score	0.028784 (rank : 225)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	603	Shared Neighborhood Hits	34
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

TCOF_HUMAN
NC score	0.027790 (rank : 226)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SETX_HUMAN
NC score	0.024528 (rank : 227)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	368	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZCH11_HUMAN
NC score	0.024193 (rank : 228)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

NCOR1_HUMAN
NC score	0.022001 (rank : 229)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	577	Shared Neighborhood Hits	32
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

FA13A_HUMAN
NC score	0.021946 (rank : 230)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

DDX46_MOUSE
NC score	0.019882 (rank : 231)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	358	Shared Neighborhood Hits	21
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX46_HUMAN
NC score	0.019862 (rank : 232)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	357	Shared Neighborhood Hits	19
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

ARHGF_HUMAN
NC score	0.019687 (rank : 233)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

AP3B2_HUMAN
NC score	0.018614 (rank : 234)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP3B2_MOUSE
NC score	0.017673 (rank : 235)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

K1688_MOUSE
NC score	0.017177 (rank : 236)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

TOP2A_HUMAN
NC score	0.016086 (rank : 237)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

MYO9B_HUMAN
NC score	0.015574 (rank : 238)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	641	Shared Neighborhood Hits	36
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

LPIN2_HUMAN
NC score	0.015437 (rank : 239)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

TAF9_MOUSE
NC score	0.014150 (rank : 240)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TXLNB_HUMAN
NC score	0.013978 (rank : 241)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	912	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

SRR35_HUMAN
NC score	0.013339 (rank : 242)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

H2BWT_HUMAN
NC score	0.012383 (rank : 243)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2G1	Gene names	H2BFWT
Domain Architecture	No domain graphic available
Description	Histone H2B type W-T (H2B histone family member W testis-specific).

ARRD1_MOUSE
NC score	0.012350 (rank : 244)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CNGB3_HUMAN
NC score	0.010107 (rank : 245)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

UNC5B_HUMAN
NC score	0.008984 (rank : 246)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

MFN1_MOUSE
NC score	0.007927 (rank : 247)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

CEP57_MOUSE
NC score	0.006517 (rank : 248)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	580	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

PRP4B_MOUSE
NC score	0.004848 (rank : 249)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	1040	Shared Neighborhood Hits	28
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

MYH3_HUMAN
NC score	0.004365 (rank : 250)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	1660	Shared Neighborhood Hits	41
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

EP15_HUMAN
NC score	0.003540 (rank : 251)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	1021	Shared Neighborhood Hits	18
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

LHX61_MOUSE
NC score	0.002980 (rank : 252)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

ZN655_HUMAN
NC score	0.002253 (rank : 253)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N720, Q8IV00, Q8TA89, Q96EZ3	Gene names	ZNF655, VIK
Domain Architecture	No domain graphic available
Description	Zinc finger protein 655 (Vav-interacting Krueppel-like protein).

SPEG_MOUSE
NC score	0.001574 (rank : 254)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	1959	Shared Neighborhood Hits	41
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MTR1L_HUMAN
NC score	0.000417 (rank : 255)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	1180	Shared Neighborhood Hits	19
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

ZN75A_HUMAN
NC score	-0.001539 (rank : 256)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	720	Shared Neighborhood Hits	5
SwissProt Accessions	Q96N20, Q92669	Gene names	ZNF75A
Domain Architecture	No domain graphic available
Description	Zinc finger protein 75A.

ZN667_MOUSE
NC score	-0.002641 (rank : 257)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q2TL60	Gene names	Znf667, Mip1, Zfp667
Domain Architecture	No domain graphic available
Description	Zinc finger protein 667 (Myocardial ischemic preconditioning up- regulated protein 1).

CDKL3_MOUSE
NC score	-0.004140 (rank : 258)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	857	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).