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Network neighborhood for query Sequence : MFN1_MOUSE

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MFN1_MOUSE
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MFN1_HUMAN
θ value	0 (rank : 1)	NC score	0.991079 (rank : 2)
Query Neighborhood Hits	55	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

MFN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	55	Target Neighborhood Hits	55	Shared Neighborhood Hits	55
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

MFN2_HUMAN
θ value	0 (rank : 3)	NC score	0.981364 (rank : 4)
Query Neighborhood Hits	55	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

MFN2_MOUSE
θ value	0 (rank : 4)	NC score	0.982764 (rank : 3)
Query Neighborhood Hits	55	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	Q80U63, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2	Gene names	Mfn2, Kiaa0214, Marf
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2) (Hypertension- related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein).

ROCK1_HUMAN
θ value	0.0193708 (rank : 5)	NC score	0.023314 (rank : 43)
Query Neighborhood Hits	55	Target Neighborhood Hits	2000	Shared Neighborhood Hits	39
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

HOME1_HUMAN
θ value	0.0736092 (rank : 6)	NC score	0.074809 (rank : 5)
Query Neighborhood Hits	55	Target Neighborhood Hits	564	Shared Neighborhood Hits	34
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

HOME1_MOUSE
θ value	0.0736092 (rank : 7)	NC score	0.074683 (rank : 6)
Query Neighborhood Hits	55	Target Neighborhood Hits	630	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

TRI18_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.016420 (rank : 50)
Query Neighborhood Hits	55	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

ROCK1_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.020318 (rank : 46)
Query Neighborhood Hits	55	Target Neighborhood Hits	2126	Shared Neighborhood Hits	39
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

MACF1_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.039536 (rank : 10)
Query Neighborhood Hits	55	Target Neighborhood Hits	1313	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACF1_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.036960 (rank : 13)
Query Neighborhood Hits	55	Target Neighborhood Hits	1341	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.041709 (rank : 9)
Query Neighborhood Hits	55	Target Neighborhood Hits	1321	Shared Neighborhood Hits	38
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CK5P2_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.036252 (rank : 14)
Query Neighborhood Hits	55	Target Neighborhood Hits	1151	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

NIN_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.037992 (rank : 12)
Query Neighborhood Hits	55	Target Neighborhood Hits	1416	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

ANR26_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.026799 (rank : 31)
Query Neighborhood Hits	55	Target Neighborhood Hits	1614	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CE290_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.031687 (rank : 19)
Query Neighborhood Hits	55	Target Neighborhood Hits	1553	Shared Neighborhood Hits	38
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CN145_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.030385 (rank : 25)
Query Neighborhood Hits	55	Target Neighborhood Hits	1196	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

IFT81_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.030570 (rank : 23)
Query Neighborhood Hits	55	Target Neighborhood Hits	959	Shared Neighborhood Hits	35
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

KNTC2_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.031742 (rank : 18)
Query Neighborhood Hits	55	Target Neighborhood Hits	673	Shared Neighborhood Hits	35
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

BRCA2_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.020391 (rank : 45)
Query Neighborhood Hits	55	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

GIMA4_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.055553 (rank : 7)
Query Neighborhood Hits	55	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JY3	Gene names	Gimap4, Ian1, Imap4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein).

HMMR_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.033608 (rank : 15)
Query Neighborhood Hits	55	Target Neighborhood Hits	1082	Shared Neighborhood Hits	38
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MYO5C_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.032041 (rank : 17)
Query Neighborhood Hits	55	Target Neighborhood Hits	1206	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NEMO_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.028638 (rank : 28)
Query Neighborhood Hits	55	Target Neighborhood Hits	820	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

OPA1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.041955 (rank : 8)
Query Neighborhood Hits	55	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

SAMD9_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.025487 (rank : 36)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q5K651, Q6P080, Q75N21, Q8IVG6, Q9NXS8	Gene names	SAMD9, KIAA2004, OEF1
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 9.

GOGA4_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.030549 (rank : 24)
Query Neighborhood Hits	55	Target Neighborhood Hits	1939	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LAMA2_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.015906 (rank : 51)
Query Neighborhood Hits	55	Target Neighborhood Hits	1198	Shared Neighborhood Hits	36
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

OPA1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.038497 (rank : 11)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

UACA_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.024284 (rank : 39)
Query Neighborhood Hits	55	Target Neighborhood Hits	1622	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

EEA1_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.026657 (rank : 32)
Query Neighborhood Hits	55	Target Neighborhood Hits	1796	Shared Neighborhood Hits	40
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GIMA2_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.024795 (rank : 37)
Query Neighborhood Hits	55	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UG22, Q96L25	Gene names	GIMAP2, IMAP2
Domain Architecture
Description	GTPase, IMAP family member 2 (Immunity-associated protein 2) (hIMAP2).

GOGB1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.029927 (rank : 26)
Query Neighborhood Hits	55	Target Neighborhood Hits	2297	Shared Neighborhood Hits	45
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

RUFY1_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.024184 (rank : 40)
Query Neighborhood Hits	55	Target Neighborhood Hits	765	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

CTGE5_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.032815 (rank : 16)
Query Neighborhood Hits	55	Target Neighborhood Hits	928	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

IFT81_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.031417 (rank : 20)
Query Neighborhood Hits	55	Target Neighborhood Hits	893	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

PXR_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.003827 (rank : 55)
Query Neighborhood Hits	55	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

TNIP3_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.029375 (rank : 27)
Query Neighborhood Hits	55	Target Neighborhood Hits	511	Shared Neighborhood Hits	32
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

ANR18_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.021719 (rank : 44)
Query Neighborhood Hits	55	Target Neighborhood Hits	1106	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

AT10D_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.003908 (rank : 54)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2X1	Gene names	Atp10d
Domain Architecture
Description	Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPVD).

CAR11_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.026283 (rank : 34)
Query Neighborhood Hits	55	Target Neighborhood Hits	690	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CASP_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.027073 (rank : 30)
Query Neighborhood Hits	55	Target Neighborhood Hits	1131	Shared Neighborhood Hits	39
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CREB3_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.011795 (rank : 52)
Query Neighborhood Hits	55	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

CUTL1_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.023644 (rank : 42)
Query Neighborhood Hits	55	Target Neighborhood Hits	1574	Shared Neighborhood Hits	39
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

ERAL_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.030764 (rank : 22)
Query Neighborhood Hits	55	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

ERAL_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.031142 (rank : 21)
Query Neighborhood Hits	55	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

GIMA7_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.019266 (rank : 48)
Query Neighborhood Hits	55	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHV1	Gene names	GIMAP7, IAN7
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 7 (Immunity-associated nucleotide 7 protein).

MX2_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.019015 (rank : 49)
Query Neighborhood Hits	55	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

MYH11_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.019317 (rank : 47)
Query Neighborhood Hits	55	Target Neighborhood Hits	1777	Shared Neighborhood Hits	39
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NUMA1_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.027360 (rank : 29)
Query Neighborhood Hits	55	Target Neighborhood Hits	1523	Shared Neighborhood Hits	37
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OLR1_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.023947 (rank : 41)
Query Neighborhood Hits	55	Target Neighborhood Hits	596	Shared Neighborhood Hits	33
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

RB6I2_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.026074 (rank : 35)
Query Neighborhood Hits	55	Target Neighborhood Hits	1584	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RUFY1_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.026629 (rank : 33)
Query Neighborhood Hits	55	Target Neighborhood Hits	848	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SP110_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.007927 (rank : 53)
Query Neighborhood Hits	55	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SYCP3_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.024356 (rank : 38)
Query Neighborhood Hits	55	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

Hits sorted by NC score

MFN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	55	Target Neighborhood Hits	55	Shared Neighborhood Hits	55
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

MFN1_HUMAN
NC score	0.991079 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	55	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

MFN2_MOUSE
NC score	0.982764 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	55	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	Q80U63, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2	Gene names	Mfn2, Kiaa0214, Marf
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2) (Hypertension- related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein).

MFN2_HUMAN
NC score	0.981364 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	55	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

HOME1_HUMAN
NC score	0.074809 (rank : 5)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	55	Target Neighborhood Hits	564	Shared Neighborhood Hits	34
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

HOME1_MOUSE
NC score	0.074683 (rank : 6)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	55	Target Neighborhood Hits	630	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

GIMA4_MOUSE
NC score	0.055553 (rank : 7)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	55	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JY3	Gene names	Gimap4, Ian1, Imap4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein).

OPA1_HUMAN
NC score	0.041955 (rank : 8)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	55	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

MACF4_HUMAN
NC score	0.041709 (rank : 9)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	55	Target Neighborhood Hits	1321	Shared Neighborhood Hits	38
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_MOUSE
NC score	0.039536 (rank : 10)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	55	Target Neighborhood Hits	1313	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

OPA1_MOUSE
NC score	0.038497 (rank : 11)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

NIN_HUMAN
NC score	0.037992 (rank : 12)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	55	Target Neighborhood Hits	1416	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

MACF1_HUMAN
NC score	0.036960 (rank : 13)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	55	Target Neighborhood Hits	1341	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

CK5P2_MOUSE
NC score	0.036252 (rank : 14)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	55	Target Neighborhood Hits	1151	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

HMMR_HUMAN
NC score	0.033608 (rank : 15)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	55	Target Neighborhood Hits	1082	Shared Neighborhood Hits	38
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CTGE5_MOUSE
NC score	0.032815 (rank : 16)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	55	Target Neighborhood Hits	928	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

MYO5C_HUMAN
NC score	0.032041 (rank : 17)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	55	Target Neighborhood Hits	1206	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

KNTC2_HUMAN
NC score	0.031742 (rank : 18)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	55	Target Neighborhood Hits	673	Shared Neighborhood Hits	35
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

CE290_HUMAN
NC score	0.031687 (rank : 19)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	55	Target Neighborhood Hits	1553	Shared Neighborhood Hits	38
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

IFT81_HUMAN
NC score	0.031417 (rank : 20)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	55	Target Neighborhood Hits	893	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ERAL_MOUSE
NC score	0.031142 (rank : 21)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	55	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

ERAL_HUMAN
NC score	0.030764 (rank : 22)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	55	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

IFT81_MOUSE
NC score	0.030570 (rank : 23)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	55	Target Neighborhood Hits	959	Shared Neighborhood Hits	35
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GOGA4_MOUSE
NC score	0.030549 (rank : 24)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	55	Target Neighborhood Hits	1939	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CN145_HUMAN
NC score	0.030385 (rank : 25)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	55	Target Neighborhood Hits	1196	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

GOGB1_HUMAN
NC score	0.029927 (rank : 26)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	55	Target Neighborhood Hits	2297	Shared Neighborhood Hits	45
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TNIP3_HUMAN
NC score	0.029375 (rank : 27)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	55	Target Neighborhood Hits	511	Shared Neighborhood Hits	32
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

NEMO_HUMAN
NC score	0.028638 (rank : 28)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	55	Target Neighborhood Hits	820	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NUMA1_HUMAN
NC score	0.027360 (rank : 29)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	55	Target Neighborhood Hits	1523	Shared Neighborhood Hits	37
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CASP_HUMAN
NC score	0.027073 (rank : 30)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	55	Target Neighborhood Hits	1131	Shared Neighborhood Hits	39
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

ANR26_HUMAN
NC score	0.026799 (rank : 31)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	55	Target Neighborhood Hits	1614	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

EEA1_HUMAN
NC score	0.026657 (rank : 32)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	55	Target Neighborhood Hits	1796	Shared Neighborhood Hits	40
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RUFY1_HUMAN
NC score	0.026629 (rank : 33)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	55	Target Neighborhood Hits	848	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

CAR11_HUMAN
NC score	0.026283 (rank : 34)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	55	Target Neighborhood Hits	690	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

RB6I2_HUMAN
NC score	0.026074 (rank : 35)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	55	Target Neighborhood Hits	1584	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SAMD9_HUMAN
NC score	0.025487 (rank : 36)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q5K651, Q6P080, Q75N21, Q8IVG6, Q9NXS8	Gene names	SAMD9, KIAA2004, OEF1
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 9.

GIMA2_HUMAN
NC score	0.024795 (rank : 37)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	55	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UG22, Q96L25	Gene names	GIMAP2, IMAP2
Domain Architecture
Description	GTPase, IMAP family member 2 (Immunity-associated protein 2) (hIMAP2).

SYCP3_HUMAN
NC score	0.024356 (rank : 38)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	55	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

UACA_HUMAN
NC score	0.024284 (rank : 39)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	55	Target Neighborhood Hits	1622	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

RUFY1_MOUSE
NC score	0.024184 (rank : 40)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	55	Target Neighborhood Hits	765	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

OLR1_MOUSE
NC score	0.023947 (rank : 41)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	55	Target Neighborhood Hits	596	Shared Neighborhood Hits	33
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

CUTL1_HUMAN
NC score	0.023644 (rank : 42)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	55	Target Neighborhood Hits	1574	Shared Neighborhood Hits	39
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

ROCK1_HUMAN
NC score	0.023314 (rank : 43)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	55	Target Neighborhood Hits	2000	Shared Neighborhood Hits	39
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ANR18_HUMAN
NC score	0.021719 (rank : 44)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	55	Target Neighborhood Hits	1106	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BRCA2_HUMAN
NC score	0.020391 (rank : 45)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	55	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

ROCK1_MOUSE
NC score	0.020318 (rank : 46)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	55	Target Neighborhood Hits	2126	Shared Neighborhood Hits	39
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

MYH11_MOUSE
NC score	0.019317 (rank : 47)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	55	Target Neighborhood Hits	1777	Shared Neighborhood Hits	39
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GIMA7_HUMAN
NC score	0.019266 (rank : 48)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	55	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHV1	Gene names	GIMAP7, IAN7
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 7 (Immunity-associated nucleotide 7 protein).

MX2_HUMAN
NC score	0.019015 (rank : 49)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	55	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

TRI18_HUMAN
NC score	0.016420 (rank : 50)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	55	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

LAMA2_MOUSE
NC score	0.015906 (rank : 51)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	55	Target Neighborhood Hits	1198	Shared Neighborhood Hits	36
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CREB3_MOUSE
NC score	0.011795 (rank : 52)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	55	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

SP110_HUMAN
NC score	0.007927 (rank : 53)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	55	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

AT10D_MOUSE
NC score	0.003908 (rank : 54)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2X1	Gene names	Atp10d
Domain Architecture
Description	Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPVD).

PXR_MOUSE
NC score	0.003827 (rank : 55)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	55	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).