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Network neighborhood for query Sequence : MFN1_HUMAN

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MFN1_HUMAN
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MFN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

MFN1_MOUSE
θ value	0 (rank : 2)	NC score	0.991079 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

MFN2_HUMAN
θ value	0 (rank : 3)	NC score	0.974451 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

MFN2_MOUSE
θ value	0 (rank : 4)	NC score	0.976155 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	52	Shared Neighborhood Hits	8
SwissProt Accessions	Q80U63, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2	Gene names	Mfn2, Kiaa0214, Marf
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2) (Hypertension- related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein).

MX1_HUMAN
θ value	0.000602161 (rank : 5)	NC score	0.097781 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

HOME1_HUMAN
θ value	0.00509761 (rank : 6)	NC score	0.085724 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	564	Shared Neighborhood Hits	39
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

HOME1_MOUSE
θ value	0.00509761 (rank : 7)	NC score	0.084334 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	630	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

ROCK1_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.023618 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	2000	Shared Neighborhood Hits	49
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

MX1_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.085865 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

OPA1_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.091757 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

MX2_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.083777 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

OPA1_MOUSE
θ value	0.21417 (rank : 12)	NC score	0.088694 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

MACF1_MOUSE
θ value	0.365318 (rank : 13)	NC score	0.038860 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1313	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

LUM_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.015529 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

NIN_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.041367 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	1416	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

LUM_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.014992 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	P51885, Q3TP25, Q99JZ3, Q9CXK0	Gene names	Lum, Lcn, Ldc
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

ROCK1_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.020555 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	2126	Shared Neighborhood Hits	49
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SM1L2_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.031952 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	1019	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

CI093_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.035212 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	1088	Shared Neighborhood Hits	46
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

MACF1_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.036386 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	1341	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.040976 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	1321	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CK5P2_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.038717 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	1151	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

RBP26_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.022896 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

VDP_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.036233 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	645	Shared Neighborhood Hits	40
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

GOGA4_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.033265 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	1939	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SAPS2_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.014712 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

CAR11_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.030682 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

GIMA4_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.051731 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JY3	Gene names	Gimap4, Ian1, Imap4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein).

MX2_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.080920 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

MYH9_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.022699 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	1762	Shared Neighborhood Hits	44
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SYCP1_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.032688 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	1456	Shared Neighborhood Hits	47
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ANR18_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.024128 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	1106	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR26_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.025704 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	1554	Shared Neighborhood Hits	46
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

APOA4_MOUSE
θ value	4.03905 (rank : 34)	NC score	0.026862 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	435	Shared Neighborhood Hits	30
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

CK5P2_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.032489 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	1433	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CTGE5_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.033976 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	928	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

FLIP1_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.031858 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	1176	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GAS8_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.028247 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	622	Shared Neighborhood Hits	36
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MYH9_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.022038 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	1829	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SYT6_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.005303 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	132	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

DYN1_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.051650 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.052020 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

GIMA2_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.022280 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UG22, Q96L25	Gene names	GIMAP2, IMAP2
Domain Architecture
Description	GTPase, IMAP family member 2 (Immunity-associated protein 2) (hIMAP2).

HMMR_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.035598 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	1082	Shared Neighborhood Hits	44
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

LNK_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.011027 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	132	Shared Neighborhood Hits	2
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MYOC_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.019690 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	489	Shared Neighborhood Hits	36
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

RUFY1_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.026381 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	848	Shared Neighborhood Hits	45
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SYCP3_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.027395 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

UACA_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.026788 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	1622	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AL2SE_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.012551 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

ANR26_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.028780 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	1614	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

OFD1_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.031374 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

RBP2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.013308 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

SDCG8_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.024513 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	886	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TPR_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.028327 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	1921	Shared Neighborhood Hits	46
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

AKAP9_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.031918 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	1710	Shared Neighborhood Hits	46
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CD226_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.011460 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4F0	Gene names	Cd226, Pta1
Domain Architecture
Description	CD226 antigen precursor (Platelet and T-cell activation antigen 1).

CN145_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.030344 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	1196	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DMD_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.027221 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DNM1L_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.053660 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.053440 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

FBXL5_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.014208 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FBXL5_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.014576 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FLIP1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.030136 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	1405	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

KLC1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.013442 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	471	Shared Neighborhood Hits	34
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

MYH3_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.021074 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	1660	Shared Neighborhood Hits	46
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NIN_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.034144 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	1376	Shared Neighborhood Hits	44
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RB6I2_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.027921 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	1584	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RBP22_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.017943 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

SLK_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.007186 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	1775	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ZN451_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.002345 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	643	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

Hits sorted by NC score

MFN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

MFN1_MOUSE
NC score	0.991079 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

MFN2_MOUSE
NC score	0.976155 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	52	Shared Neighborhood Hits	8
SwissProt Accessions	Q80U63, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2	Gene names	Mfn2, Kiaa0214, Marf
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2) (Hypertension- related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein).

MFN2_HUMAN
NC score	0.974451 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

MX1_HUMAN
NC score	0.097781 (rank : 5)	θ value	0.000602161 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

OPA1_HUMAN
NC score	0.091757 (rank : 6)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_MOUSE
NC score	0.088694 (rank : 7)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

MX1_MOUSE
NC score	0.085865 (rank : 8)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

HOME1_HUMAN
NC score	0.085724 (rank : 9)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	564	Shared Neighborhood Hits	39
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

HOME1_MOUSE
NC score	0.084334 (rank : 10)	θ value	0.00509761 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	630	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

MX2_MOUSE
NC score	0.083777 (rank : 11)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX2_HUMAN
NC score	0.080920 (rank : 12)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

DNM1L_HUMAN
NC score	0.053660 (rank : 13)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
NC score	0.053440 (rank : 14)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

DYN1_MOUSE
NC score	0.052020 (rank : 15)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

GIMA4_MOUSE
NC score	0.051731 (rank : 16)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JY3	Gene names	Gimap4, Ian1, Imap4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein).

DYN1_HUMAN
NC score	0.051650 (rank : 17)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

NIN_HUMAN
NC score	0.041367 (rank : 18)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	1416	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

MACF4_HUMAN
NC score	0.040976 (rank : 19)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	1321	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_MOUSE
NC score	0.038860 (rank : 20)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	1313	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

CK5P2_MOUSE
NC score	0.038717 (rank : 21)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	1151	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

MACF1_HUMAN
NC score	0.036386 (rank : 22)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1341	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

VDP_HUMAN
NC score	0.036233 (rank : 23)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	645	Shared Neighborhood Hits	40
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

HMMR_HUMAN
NC score	0.035598 (rank : 24)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	1082	Shared Neighborhood Hits	44
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CI093_HUMAN
NC score	0.035212 (rank : 25)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	1088	Shared Neighborhood Hits	46
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

NIN_MOUSE
NC score	0.034144 (rank : 26)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	1376	Shared Neighborhood Hits	44
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CTGE5_MOUSE
NC score	0.033976 (rank : 27)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	928	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

GOGA4_MOUSE
NC score	0.033265 (rank : 28)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	1939	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SYCP1_MOUSE
NC score	0.032688 (rank : 29)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	1456	Shared Neighborhood Hits	47
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CK5P2_HUMAN
NC score	0.032489 (rank : 30)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	1433	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

SM1L2_HUMAN
NC score	0.031952 (rank : 31)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	1019	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

AKAP9_HUMAN
NC score	0.031918 (rank : 32)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	1710	Shared Neighborhood Hits	46
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

FLIP1_MOUSE
NC score	0.031858 (rank : 33)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	1176	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

OFD1_HUMAN
NC score	0.031374 (rank : 34)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

CAR11_HUMAN
NC score	0.030682 (rank : 35)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CN145_HUMAN
NC score	0.030344 (rank : 36)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	1196	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

FLIP1_HUMAN
NC score	0.030136 (rank : 37)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	1405	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ANR26_HUMAN
NC score	0.028780 (rank : 38)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	1614	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TPR_HUMAN
NC score	0.028327 (rank : 39)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	1921	Shared Neighborhood Hits	46
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

GAS8_MOUSE
NC score	0.028247 (rank : 40)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	622	Shared Neighborhood Hits	36
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RB6I2_HUMAN
NC score	0.027921 (rank : 41)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	1584	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SYCP3_HUMAN
NC score	0.027395 (rank : 42)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

DMD_HUMAN
NC score	0.027221 (rank : 43)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

APOA4_MOUSE
NC score	0.026862 (rank : 44)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	435	Shared Neighborhood Hits	30
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

UACA_HUMAN
NC score	0.026788 (rank : 45)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	1622	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

RUFY1_HUMAN
NC score	0.026381 (rank : 46)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	848	Shared Neighborhood Hits	45
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

ANR26_MOUSE
NC score	0.025704 (rank : 47)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	1554	Shared Neighborhood Hits	46
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SDCG8_MOUSE
NC score	0.024513 (rank : 48)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	886	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

ANR18_HUMAN
NC score	0.024128 (rank : 49)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	1106	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ROCK1_HUMAN
NC score	0.023618 (rank : 50)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	2000	Shared Neighborhood Hits	49
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

RBP26_HUMAN
NC score	0.022896 (rank : 51)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

MYH9_HUMAN
NC score	0.022699 (rank : 52)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	1762	Shared Neighborhood Hits	44
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GIMA2_HUMAN
NC score	0.022280 (rank : 53)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UG22, Q96L25	Gene names	GIMAP2, IMAP2
Domain Architecture
Description	GTPase, IMAP family member 2 (Immunity-associated protein 2) (hIMAP2).

MYH9_MOUSE
NC score	0.022038 (rank : 54)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	1829	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH3_HUMAN
NC score	0.021074 (rank : 55)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	1660	Shared Neighborhood Hits	46
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

ROCK1_MOUSE
NC score	0.020555 (rank : 56)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	2126	Shared Neighborhood Hits	49
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

MYOC_HUMAN
NC score	0.019690 (rank : 57)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	489	Shared Neighborhood Hits	36
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

RBP22_HUMAN
NC score	0.017943 (rank : 58)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

LUM_HUMAN
NC score	0.015529 (rank : 59)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

LUM_MOUSE
NC score	0.014992 (rank : 60)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	P51885, Q3TP25, Q99JZ3, Q9CXK0	Gene names	Lum, Lcn, Ldc
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

SAPS2_MOUSE
NC score	0.014712 (rank : 61)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

FBXL5_MOUSE
NC score	0.014576 (rank : 62)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXL5_HUMAN
NC score	0.014208 (rank : 63)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

KLC1_HUMAN
NC score	0.013442 (rank : 64)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	471	Shared Neighborhood Hits	34
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

RBP2_HUMAN
NC score	0.013308 (rank : 65)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

AL2SE_HUMAN
NC score	0.012551 (rank : 66)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

CD226_MOUSE
NC score	0.011460 (rank : 67)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4F0	Gene names	Cd226, Pta1
Domain Architecture
Description	CD226 antigen precursor (Platelet and T-cell activation antigen 1).

LNK_MOUSE
NC score	0.011027 (rank : 68)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	132	Shared Neighborhood Hits	2
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

SLK_HUMAN
NC score	0.007186 (rank : 69)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	1775	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SYT6_MOUSE
NC score	0.005303 (rank : 70)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	132	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

ZN451_MOUSE
NC score	0.002345 (rank : 71)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	643	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.