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Network neighborhood for query Sequence : DNM1L_HUMAN

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DNM1L_HUMAN
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DNM1L_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
θ value	0 (rank : 2)	NC score	0.999064 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

DYN1_HUMAN
θ value	1.20984e-129 (rank : 3)	NC score	0.939219 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	1.20984e-129 (rank : 4)	NC score	0.944844 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN2_MOUSE
θ value	2.78914e-126 (rank : 5)	NC score	0.947684 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN2_HUMAN
θ value	6.21357e-126 (rank : 6)	NC score	0.947469 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN3_HUMAN
θ value	1.0968e-122 (rank : 7)	NC score	0.941171 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

MX2_MOUSE
θ value	2.94719e-51 (rank : 8)	NC score	0.883088 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
θ value	1.46268e-50 (rank : 9)	NC score	0.883303 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX1_HUMAN
θ value	5.55816e-50 (rank : 10)	NC score	0.882693 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_HUMAN
θ value	7.25919e-50 (rank : 11)	NC score	0.877542 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

OPA1_HUMAN
θ value	2.87452e-22 (rank : 12)	NC score	0.711925 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_MOUSE
θ value	2.87452e-22 (rank : 13)	NC score	0.714856 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

DNMT1_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.024632 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	401	Shared Neighborhood Hits	6
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SPB8_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.008675 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P50452	Gene names	SERPINB8, PI8
Domain Architecture
Description	Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Protease inhibitor 8).

CT026_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.037752 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

MYH4_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.005546 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	1476	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

PTPRF_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.002377 (rank : 43)
Query Neighborhood Hits	39	Target Neighborhood Hits	489	Shared Neighborhood Hits	2
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

SFRIP_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.023421 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	530	Shared Neighborhood Hits	4
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

KGUA_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.015612 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

ARHG1_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.007617 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

RAP2A_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.003189 (rank : 42)
Query Neighborhood Hits	39	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	P10114, Q5JSC2	Gene names	RAP2A
Domain Architecture
Description	Ras-related protein Rap-2a (RbBP-30).

RAP2A_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.003224 (rank : 41)
Query Neighborhood Hits	39	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZJ1, Q3USK1, Q7TSK4, Q810A2, Q9D3D5	Gene names	Rap2a
Domain Architecture	No domain graphic available
Description	Ras-related protein Rap-2a.

RBP1_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.011541 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	493	Shared Neighborhood Hits	11
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

NAF1_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.005516 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	937	Shared Neighborhood Hits	9
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

KCC4_HUMAN
θ value	5.27518 (rank : 26)	NC score	-0.001643 (rank : 45)
Query Neighborhood Hits	39	Target Neighborhood Hits	841	Shared Neighborhood Hits	3
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

MYH1_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.004818 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	1461	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

STMN1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.013572 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	554	Shared Neighborhood Hits	10
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

TM1L1_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.009138 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

CAR15_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.009416 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

MYH3_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.004064 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	1660	Shared Neighborhood Hits	12
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

STMN1_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.012292 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	560	Shared Neighborhood Hits	10
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

BFSP2_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.004787 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

FR1OP_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.009561 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	O95684, Q49AI0, Q5R3F6, Q96EW1	Gene names	FGFR1OP, FOP
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

MFN1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.053660 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

MYH8_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.004863 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	1610	Shared Neighborhood Hits	14
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.004305 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	1600	Shared Neighborhood Hits	12
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NAL12_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.003882 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

ULK2_HUMAN
θ value	8.99809 (rank : 39)	NC score	-0.001558 (rank : 44)
Query Neighborhood Hits	39	Target Neighborhood Hits	979	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

CNKR1_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.064282 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.061299 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.061354 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH1_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.052116 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.052218 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.050104 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

Hits sorted by NC score

DNM1L_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
NC score	0.999064 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

DYN2_MOUSE
NC score	0.947684 (rank : 3)	θ value	2.78914e-126 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN2_HUMAN
NC score	0.947469 (rank : 4)	θ value	6.21357e-126 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN1_MOUSE
NC score	0.944844 (rank : 5)	θ value	1.20984e-129 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN3_HUMAN
NC score	0.941171 (rank : 6)	θ value	1.0968e-122 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DYN1_HUMAN
NC score	0.939219 (rank : 7)	θ value	1.20984e-129 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

MX1_MOUSE
NC score	0.883303 (rank : 8)	θ value	1.46268e-50 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_MOUSE
NC score	0.883088 (rank : 9)	θ value	2.94719e-51 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_HUMAN
NC score	0.882693 (rank : 10)	θ value	5.55816e-50 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_HUMAN
NC score	0.877542 (rank : 11)	θ value	7.25919e-50 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

OPA1_MOUSE
NC score	0.714856 (rank : 12)	θ value	2.87452e-22 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_HUMAN
NC score	0.711925 (rank : 13)	θ value	2.87452e-22 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

CNKR1_HUMAN
NC score	0.064282 (rank : 14)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_MOUSE
NC score	0.061354 (rank : 15)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	39	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.061299 (rank : 16)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	39	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

MFN1_HUMAN
NC score	0.053660 (rank : 17)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

CYH1_MOUSE
NC score	0.052218 (rank : 18)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	39	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
NC score	0.052116 (rank : 19)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	39	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_HUMAN
NC score	0.050104 (rank : 20)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	39	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CT026_HUMAN
NC score	0.037752 (rank : 21)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

DNMT1_HUMAN
NC score	0.024632 (rank : 22)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	401	Shared Neighborhood Hits	6
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SFRIP_HUMAN
NC score	0.023421 (rank : 23)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	530	Shared Neighborhood Hits	4
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

KGUA_MOUSE
NC score	0.015612 (rank : 24)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

STMN1_HUMAN
NC score	0.013572 (rank : 25)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	554	Shared Neighborhood Hits	10
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
NC score	0.012292 (rank : 26)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	560	Shared Neighborhood Hits	10
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

RBP1_MOUSE
NC score	0.011541 (rank : 27)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	493	Shared Neighborhood Hits	11
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

FR1OP_HUMAN
NC score	0.009561 (rank : 28)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	O95684, Q49AI0, Q5R3F6, Q96EW1	Gene names	FGFR1OP, FOP
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

CAR15_MOUSE
NC score	0.009416 (rank : 29)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

TM1L1_HUMAN
NC score	0.009138 (rank : 30)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

SPB8_HUMAN
NC score	0.008675 (rank : 31)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P50452	Gene names	SERPINB8, PI8
Domain Architecture
Description	Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Protease inhibitor 8).

ARHG1_HUMAN
NC score	0.007617 (rank : 32)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

MYH4_MOUSE
NC score	0.005546 (rank : 33)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	1476	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NAF1_HUMAN
NC score	0.005516 (rank : 34)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	937	Shared Neighborhood Hits	9
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

MYH8_HUMAN
NC score	0.004863 (rank : 35)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	1610	Shared Neighborhood Hits	14
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH1_MOUSE
NC score	0.004818 (rank : 36)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	1461	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

BFSP2_MOUSE
NC score	0.004787 (rank : 37)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

MYH8_MOUSE
NC score	0.004305 (rank : 38)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	1600	Shared Neighborhood Hits	12
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH3_HUMAN
NC score	0.004064 (rank : 39)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	1660	Shared Neighborhood Hits	12
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NAL12_HUMAN
NC score	0.003882 (rank : 40)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

RAP2A_MOUSE
NC score	0.003224 (rank : 41)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZJ1, Q3USK1, Q7TSK4, Q810A2, Q9D3D5	Gene names	Rap2a
Domain Architecture	No domain graphic available
Description	Ras-related protein Rap-2a.

RAP2A_HUMAN
NC score	0.003189 (rank : 42)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	P10114, Q5JSC2	Gene names	RAP2A
Domain Architecture
Description	Ras-related protein Rap-2a (RbBP-30).

PTPRF_HUMAN
NC score	0.002377 (rank : 43)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	489	Shared Neighborhood Hits	2
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

ULK2_HUMAN
NC score	-0.001558 (rank : 44)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	979	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

KCC4_HUMAN
NC score	-0.001643 (rank : 45)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	841	Shared Neighborhood Hits	3
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).