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Network neighborhood for query Sequence : TM1L1_HUMAN

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TM1L1_HUMAN
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TM1L1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TM1L1_MOUSE
θ value	0 (rank : 2)	NC score	0.992571 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TOM1_MOUSE
θ value	3.71096e-62 (rank : 3)	NC score	0.913547 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_HUMAN
θ value	6.99855e-61 (rank : 4)	NC score	0.912373 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

GGA2_HUMAN
θ value	6.85773e-16 (rank : 5)	NC score	0.637563 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA3_HUMAN
θ value	6.85773e-16 (rank : 6)	NC score	0.665416 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	127	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
θ value	1.29331e-14 (rank : 7)	NC score	0.646120 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

STAM2_HUMAN
θ value	1.68911e-14 (rank : 8)	NC score	0.493568 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	288	Shared Neighborhood Hits	17
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	2.20605e-14 (rank : 9)	NC score	0.478496 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

GGA1_HUMAN
θ value	6.41864e-14 (rank : 10)	NC score	0.639318 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_MOUSE
θ value	1.42992e-13 (rank : 11)	NC score	0.642276 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	128	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA2_MOUSE
θ value	1.86753e-13 (rank : 12)	NC score	0.631511 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

STAM1_HUMAN
θ value	5.43371e-13 (rank : 13)	NC score	0.477962 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	7.09661e-13 (rank : 14)	NC score	0.471422 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	273	Shared Neighborhood Hits	16
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

HGS_MOUSE
θ value	1.25267e-09 (rank : 15)	NC score	0.430300 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	2.13673e-09 (rank : 16)	NC score	0.432688 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	517	Shared Neighborhood Hits	23
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

GOGA1_HUMAN
θ value	0.0736092 (rank : 17)	NC score	0.027454 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	1222	Shared Neighborhood Hits	20
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

AKAP9_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.030095 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	1710	Shared Neighborhood Hits	25
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

TBCD1_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.045877 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

TRI66_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.021949 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	491	Shared Neighborhood Hits	6
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CABYR_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.063359 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

KCC1G_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.003030 (rank : 56)
Query Neighborhood Hits	52	Target Neighborhood Hits	850	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NX5, Q86UH5, Q9Y3J7	Gene names	CAMK1G, VWS1
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

S13A4_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.021466 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKG4	Gene names	SLC13A4, SUT1
Domain Architecture
Description	Solute carrier family 13 member 4 (Na(+)/sulfate cotransporter SUT-1).

CE290_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.024728 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	1553	Shared Neighborhood Hits	25
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

PDCL3_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.037785 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

CENPE_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.017080 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	2060	Shared Neighborhood Hits	30
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DMD_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.020276 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	1111	Shared Neighborhood Hits	20
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ABEC4_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.024806 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WW27, Q8N7F6	Gene names	APOBEC4, C1orf169
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

SNX23_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.010521 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	944	Shared Neighborhood Hits	14
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

RNF8_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.015149 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	622	Shared Neighborhood Hits	14
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

VDP_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.025523 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	645	Shared Neighborhood Hits	17
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ARHGC_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.007553 (rank : 54)
Query Neighborhood Hits	52	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BPAEA_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.012915 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	1369	Shared Neighborhood Hits	19
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAR10_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.013083 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	569	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CENPK_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.021247 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

DMD_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.020412 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	1135	Shared Neighborhood Hits	20
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DNM1L_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.009138 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

RIN2_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.011747 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

ANGL3_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.009416 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

HMMR_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.013373 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	1082	Shared Neighborhood Hits	18
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PRP4B_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.001573 (rank : 57)
Query Neighborhood Hits	52	Target Neighborhood Hits	1040	Shared Neighborhood Hits	6
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SETD2_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.013712 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	412	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

TBCD4_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.022685 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

USH1C_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.011583 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	557	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WASF3_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.012355 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	204	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

AF10_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.005974 (rank : 55)
Query Neighborhood Hits	52	Target Neighborhood Hits	198	Shared Neighborhood Hits	2
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

DNMT2_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.012100 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

GABT_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.011032 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P61922, Q8BZA3	Gene names	Abat, Gabat
Domain Architecture
Description	4-aminobutyrate aminotransferase, mitochondrial precursor (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (GABA-T) (L-AIBAT).

MYO5A_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.007616 (rank : 53)
Query Neighborhood Hits	52	Target Neighborhood Hits	1092	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

PRP4B_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.001260 (rank : 58)
Query Neighborhood Hits	52	Target Neighborhood Hits	1030	Shared Neighborhood Hits	6
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

UACA_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.008987 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	1622	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

WASF3_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.011376 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

AP1G1_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.093113 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.089915 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.080715 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.085829 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

STAC3_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.053463 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.054275 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

Hits sorted by NC score

TM1L1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TM1L1_MOUSE
NC score	0.992571 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TOM1_MOUSE
NC score	0.913547 (rank : 3)	θ value	3.71096e-62 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_HUMAN
NC score	0.912373 (rank : 4)	θ value	6.99855e-61 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

GGA3_HUMAN
NC score	0.665416 (rank : 5)	θ value	6.85773e-16 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	127	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
NC score	0.646120 (rank : 6)	θ value	1.29331e-14 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA1_MOUSE
NC score	0.642276 (rank : 7)	θ value	1.42992e-13 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	128	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_HUMAN
NC score	0.639318 (rank : 8)	θ value	6.41864e-14 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA2_HUMAN
NC score	0.637563 (rank : 9)	θ value	6.85773e-16 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
NC score	0.631511 (rank : 10)	θ value	1.86753e-13 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

STAM2_HUMAN
NC score	0.493568 (rank : 11)	θ value	1.68911e-14 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	288	Shared Neighborhood Hits	17
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
NC score	0.478496 (rank : 12)	θ value	2.20605e-14 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STAM1_HUMAN
NC score	0.477962 (rank : 13)	θ value	5.43371e-13 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
NC score	0.471422 (rank : 14)	θ value	7.09661e-13 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	273	Shared Neighborhood Hits	16
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

HGS_HUMAN
NC score	0.432688 (rank : 15)	θ value	2.13673e-09 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	517	Shared Neighborhood Hits	23
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.430300 (rank : 16)	θ value	1.25267e-09 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

AP1G1_HUMAN
NC score	0.093113 (rank : 17)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	52	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
NC score	0.089915 (rank : 18)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	52	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_MOUSE
NC score	0.085829 (rank : 19)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_HUMAN
NC score	0.080715 (rank : 20)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	52	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

CABYR_HUMAN
NC score	0.063359 (rank : 21)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

STAC3_MOUSE
NC score	0.054275 (rank : 22)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	52	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.053463 (rank : 23)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	52	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

TBCD1_MOUSE
NC score	0.045877 (rank : 24)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

PDCL3_MOUSE
NC score	0.037785 (rank : 25)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

AKAP9_HUMAN
NC score	0.030095 (rank : 26)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	1710	Shared Neighborhood Hits	25
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GOGA1_HUMAN
NC score	0.027454 (rank : 27)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	1222	Shared Neighborhood Hits	20
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

VDP_HUMAN
NC score	0.025523 (rank : 28)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	645	Shared Neighborhood Hits	17
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ABEC4_HUMAN
NC score	0.024806 (rank : 29)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WW27, Q8N7F6	Gene names	APOBEC4, C1orf169
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

CE290_HUMAN
NC score	0.024728 (rank : 30)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	1553	Shared Neighborhood Hits	25
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TBCD4_HUMAN
NC score	0.022685 (rank : 31)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TRI66_MOUSE
NC score	0.021949 (rank : 32)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	491	Shared Neighborhood Hits	6
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

S13A4_HUMAN
NC score	0.021466 (rank : 33)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKG4	Gene names	SLC13A4, SUT1
Domain Architecture
Description	Solute carrier family 13 member 4 (Na(+)/sulfate cotransporter SUT-1).

CENPK_MOUSE
NC score	0.021247 (rank : 34)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

DMD_HUMAN
NC score	0.020412 (rank : 35)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	1135	Shared Neighborhood Hits	20
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
NC score	0.020276 (rank : 36)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	1111	Shared Neighborhood Hits	20
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

CENPE_HUMAN
NC score	0.017080 (rank : 37)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	2060	Shared Neighborhood Hits	30
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RNF8_HUMAN
NC score	0.015149 (rank : 38)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	622	Shared Neighborhood Hits	14
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

SETD2_HUMAN
NC score	0.013712 (rank : 39)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	412	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HMMR_HUMAN
NC score	0.013373 (rank : 40)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	1082	Shared Neighborhood Hits	18
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CAR10_HUMAN
NC score	0.013083 (rank : 41)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	569	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

BPAEA_HUMAN
NC score	0.012915 (rank : 42)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	1369	Shared Neighborhood Hits	19
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

WASF3_HUMAN
NC score	0.012355 (rank : 43)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	204	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

DNMT2_HUMAN
NC score	0.012100 (rank : 44)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

RIN2_MOUSE
NC score	0.011747 (rank : 45)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

USH1C_MOUSE
NC score	0.011583 (rank : 46)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	557	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WASF3_MOUSE
NC score	0.011376 (rank : 47)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

GABT_MOUSE
NC score	0.011032 (rank : 48)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P61922, Q8BZA3	Gene names	Abat, Gabat
Domain Architecture
Description	4-aminobutyrate aminotransferase, mitochondrial precursor (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA aminotransferase) (GABA-AT) (GABA-T) (L-AIBAT).

SNX23_HUMAN
NC score	0.010521 (rank : 49)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	944	Shared Neighborhood Hits	14
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ANGL3_HUMAN
NC score	0.009416 (rank : 50)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

DNM1L_HUMAN
NC score	0.009138 (rank : 51)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

UACA_HUMAN
NC score	0.008987 (rank : 52)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	1622	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MYO5A_HUMAN
NC score	0.007616 (rank : 53)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	1092	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

ARHGC_HUMAN
NC score	0.007553 (rank : 54)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

AF10_HUMAN
NC score	0.005974 (rank : 55)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	198	Shared Neighborhood Hits	2
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

KCC1G_HUMAN
NC score	0.003030 (rank : 56)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	850	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NX5, Q86UH5, Q9Y3J7	Gene names	CAMK1G, VWS1
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM- KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III).

PRP4B_MOUSE
NC score	0.001573 (rank : 57)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	1040	Shared Neighborhood Hits	6
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

PRP4B_HUMAN
NC score	0.001260 (rank : 58)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	1030	Shared Neighborhood Hits	6
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).