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Network neighborhood for query Sequence : RIN2_MOUSE

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RIN2_MOUSE
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIN2_HUMAN
θ value	0 (rank : 1)	NC score	0.991347 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN3_MOUSE
θ value	4.07447e-85 (rank : 3)	NC score	0.821314 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_HUMAN
θ value	2.64101e-84 (rank : 4)	NC score	0.839274 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN1_MOUSE
θ value	2.10232e-65 (rank : 5)	NC score	0.858053 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

RIN1_HUMAN
θ value	4.84666e-62 (rank : 6)	NC score	0.852243 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

RABX5_HUMAN
θ value	6.21693e-09 (rank : 7)	NC score	0.407234 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RABX5_MOUSE
θ value	1.17247e-07 (rank : 8)	NC score	0.442537 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

GRB14_MOUSE
θ value	2.44474e-05 (rank : 9)	NC score	0.185314 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_HUMAN
θ value	0.000158464 (rank : 10)	NC score	0.174509 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	137	Shared Neighborhood Hits	16
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

CP007_MOUSE
θ value	0.00020696 (rank : 11)	NC score	0.267802 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

GRB10_HUMAN
θ value	0.00035302 (rank : 12)	NC score	0.186911 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	0.000602161 (rank : 13)	NC score	0.185616 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB7_HUMAN
θ value	0.00102713 (rank : 14)	NC score	0.185707 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

ALS2_HUMAN
θ value	0.00390308 (rank : 15)	NC score	0.135705 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
θ value	0.00390308 (rank : 16)	NC score	0.134309 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

GRB7_MOUSE
θ value	0.00390308 (rank : 17)	NC score	0.176422 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

SH22A_MOUSE
θ value	0.0563607 (rank : 18)	NC score	0.116250 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	179	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

T22D4_HUMAN
θ value	0.0563607 (rank : 19)	NC score	0.041681 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	403	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

PHC1_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.055826 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

TENS4_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.112608 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	214	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

HSH2D_HUMAN
θ value	0.125558 (rank : 22)	NC score	0.095584 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	159	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

SON_HUMAN
θ value	0.163984 (rank : 23)	NC score	0.051591 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	1568	Shared Neighborhood Hits	19
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

GCC2_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.018821 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	1558	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.018845 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	1559	Shared Neighborhood Hits	13
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SMAL1_HUMAN
θ value	0.21417 (rank : 26)	NC score	0.030190 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CRSP2_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.040604 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	380	Shared Neighborhood Hits	9
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

TENS4_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.102910 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

HSH2D_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.095670 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MATK_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.011805 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	954	Shared Neighborhood Hits	20
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

ZN318_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.040015 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	497	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ANK2_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.015212 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	1615	Shared Neighborhood Hits	22
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

K1688_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.019187 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

ZN318_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.034163 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	642	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

BPL1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.025508 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P50747, Q99451	Gene names	HLCS
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

MATK_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.013865 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	952	Shared Neighborhood Hits	21
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

GOGA2_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.015216 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	856	Shared Neighborhood Hits	9
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

MLL3_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.026075 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	1644	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DCHS_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.018978 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

FA35A_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.021382 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEN2	Gene names	Fam35a
Domain Architecture	No domain graphic available
Description	Protein FAM35A.

LTB1L_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.003510 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	553	Shared Neighborhood Hits	3
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NACAM_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.029805 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	1866	Shared Neighborhood Hits	24
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

HRSL5_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.021047 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

HRSL5_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.020951 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CPX5, Q9CVQ2, Q9CVS0	Gene names	Hrasls5, Hrlp5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

K0562_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.017214 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

PCNT_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.010324 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	1551	Shared Neighborhood Hits	13
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PRGR_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.018538 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SMAL1_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.024352 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SOCS1_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.072826 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

ZN750_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.017469 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BNIPL_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.011179 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CRK_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.039119 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.038447 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

P55G_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.017067 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	401	Shared Neighborhood Hits	18
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RARB_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.003888 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

TM1L1_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.011747 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

ATX7_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.014519 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	328	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CNTN1_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.001509 (rank : 74)
Query Neighborhood Hits	72	Target Neighborhood Hits	431	Shared Neighborhood Hits	2
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

DIDO1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.008848 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	960	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GCM2_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.011814 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O09102, Q9QWX7, Q9Z289	Gene names	Gcm2, Gcmb
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (mGCMb).

ZN253_HUMAN
θ value	6.88961 (rank : 61)	NC score	-0.000627 (rank : 76)
Query Neighborhood Hits	72	Target Neighborhood Hits	711	Shared Neighborhood Hits	4
SwissProt Accessions	O75346	Gene names	ZNF253, BMZF1
Domain Architecture
Description	Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1).

CISH_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.019256 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q62225, Q3TC70	Gene names	Cish, Cis
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS).

CP250_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.003882 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	1805	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

JHD2A_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.010885 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

MAGD4_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.004121 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	338	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MPDZ_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.003145 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	261	Shared Neighborhood Hits	2
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NCOA6_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.017928 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	1202	Shared Neighborhood Hits	21
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PF21A_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.008577 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RX_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.001991 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	429	Shared Neighborhood Hits	4
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SOCS1_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.067988 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

SRRM1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.026105 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	966	Shared Neighborhood Hits	22
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ZN486_HUMAN
θ value	8.99809 (rank : 72)	NC score	-0.000282 (rank : 75)
Query Neighborhood Hits	72	Target Neighborhood Hits	645	Shared Neighborhood Hits	3
SwissProt Accessions	Q96H40	Gene names	ZNF486, KRBO2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 486.

AB1IP_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.087856 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.088507 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

RAPH1_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.074026 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	593	Shared Neighborhood Hits	21
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SH22A_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.058984 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

Hits sorted by NC score

RIN2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN2_HUMAN
NC score	0.991347 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN1_MOUSE
NC score	0.858053 (rank : 3)	θ value	2.10232e-65 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

RIN1_HUMAN
NC score	0.852243 (rank : 4)	θ value	4.84666e-62 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

RIN3_HUMAN
NC score	0.839274 (rank : 5)	θ value	2.64101e-84 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
NC score	0.821314 (rank : 6)	θ value	4.07447e-85 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RABX5_MOUSE
NC score	0.442537 (rank : 7)	θ value	1.17247e-07 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

RABX5_HUMAN
NC score	0.407234 (rank : 8)	θ value	6.21693e-09 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

CP007_MOUSE
NC score	0.267802 (rank : 9)	θ value	0.00020696 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

GRB10_HUMAN
NC score	0.186911 (rank : 10)	θ value	0.00035302 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB7_HUMAN
NC score	0.185707 (rank : 11)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB10_MOUSE
NC score	0.185616 (rank : 12)	θ value	0.000602161 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_MOUSE
NC score	0.185314 (rank : 13)	θ value	2.44474e-05 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_MOUSE
NC score	0.176422 (rank : 14)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRB14_HUMAN
NC score	0.174509 (rank : 15)	θ value	0.000158464 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	137	Shared Neighborhood Hits	16
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

ALS2_HUMAN
NC score	0.135705 (rank : 16)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
NC score	0.134309 (rank : 17)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

SH22A_MOUSE
NC score	0.116250 (rank : 18)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	179	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

TENS4_HUMAN
NC score	0.112608 (rank : 19)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	214	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TENS4_MOUSE
NC score	0.102910 (rank : 20)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

HSH2D_MOUSE
NC score	0.095670 (rank : 21)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_HUMAN
NC score	0.095584 (rank : 22)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	159	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

AB1IP_MOUSE
NC score	0.088507 (rank : 23)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	72	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

AB1IP_HUMAN
NC score	0.087856 (rank : 24)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

RAPH1_HUMAN
NC score	0.074026 (rank : 25)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	72	Target Neighborhood Hits	593	Shared Neighborhood Hits	21
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SOCS1_HUMAN
NC score	0.072826 (rank : 26)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

SOCS1_MOUSE
NC score	0.067988 (rank : 27)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

SH22A_HUMAN
NC score	0.058984 (rank : 28)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	72	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

PHC1_HUMAN
NC score	0.055826 (rank : 29)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

SON_HUMAN
NC score	0.051591 (rank : 30)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	1568	Shared Neighborhood Hits	19
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

T22D4_HUMAN
NC score	0.041681 (rank : 31)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	403	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

CRSP2_HUMAN
NC score	0.040604 (rank : 32)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	380	Shared Neighborhood Hits	9
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

ZN318_HUMAN
NC score	0.040015 (rank : 33)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	497	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

CRK_HUMAN
NC score	0.039119 (rank : 34)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
NC score	0.038447 (rank : 35)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

ZN318_MOUSE
NC score	0.034163 (rank : 36)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	642	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SMAL1_HUMAN
NC score	0.030190 (rank : 37)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

NACAM_MOUSE
NC score	0.029805 (rank : 38)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	1866	Shared Neighborhood Hits	24
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM1_MOUSE
NC score	0.026105 (rank : 39)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	966	Shared Neighborhood Hits	22
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MLL3_HUMAN
NC score	0.026075 (rank : 40)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	1644	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BPL1_HUMAN
NC score	0.025508 (rank : 41)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P50747, Q99451	Gene names	HLCS
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

SMAL1_MOUSE
NC score	0.024352 (rank : 42)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

FA35A_MOUSE
NC score	0.021382 (rank : 43)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEN2	Gene names	Fam35a
Domain Architecture	No domain graphic available
Description	Protein FAM35A.

HRSL5_HUMAN
NC score	0.021047 (rank : 44)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

HRSL5_MOUSE
NC score	0.020951 (rank : 45)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CPX5, Q9CVQ2, Q9CVS0	Gene names	Hrasls5, Hrlp5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

CISH_MOUSE
NC score	0.019256 (rank : 46)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q62225, Q3TC70	Gene names	Cish, Cis
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS).

K1688_HUMAN
NC score	0.019187 (rank : 47)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

DCHS_MOUSE
NC score	0.018978 (rank : 48)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

RBP24_HUMAN
NC score	0.018845 (rank : 49)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	1559	Shared Neighborhood Hits	13
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.018821 (rank : 50)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	1558	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

PRGR_MOUSE
NC score	0.018538 (rank : 51)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

NCOA6_HUMAN
NC score	0.017928 (rank : 52)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	1202	Shared Neighborhood Hits	21
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ZN750_MOUSE
NC score	0.017469 (rank : 53)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

K0562_MOUSE
NC score	0.017214 (rank : 54)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

P55G_MOUSE
NC score	0.017067 (rank : 55)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	401	Shared Neighborhood Hits	18
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

GOGA2_HUMAN
NC score	0.015216 (rank : 56)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	856	Shared Neighborhood Hits	9
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

ANK2_HUMAN
NC score	0.015212 (rank : 57)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	1615	Shared Neighborhood Hits	22
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ATX7_MOUSE
NC score	0.014519 (rank : 58)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	328	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

MATK_MOUSE
NC score	0.013865 (rank : 59)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	952	Shared Neighborhood Hits	21
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

GCM2_MOUSE
NC score	0.011814 (rank : 60)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O09102, Q9QWX7, Q9Z289	Gene names	Gcm2, Gcmb
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (mGCMb).

MATK_HUMAN
NC score	0.011805 (rank : 61)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	954	Shared Neighborhood Hits	20
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

TM1L1_HUMAN
NC score	0.011747 (rank : 62)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

BNIPL_HUMAN
NC score	0.011179 (rank : 63)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

JHD2A_HUMAN
NC score	0.010885 (rank : 64)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

PCNT_HUMAN
NC score	0.010324 (rank : 65)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	1551	Shared Neighborhood Hits	13
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

DIDO1_HUMAN
NC score	0.008848 (rank : 66)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	960	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PF21A_HUMAN
NC score	0.008577 (rank : 67)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MAGD4_HUMAN
NC score	0.004121 (rank : 68)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	338	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

RARB_HUMAN
NC score	0.003888 (rank : 69)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

CP250_HUMAN
NC score	0.003882 (rank : 70)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	1805	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

LTB1L_HUMAN
NC score	0.003510 (rank : 71)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	553	Shared Neighborhood Hits	3
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MPDZ_HUMAN
NC score	0.003145 (rank : 72)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	261	Shared Neighborhood Hits	2
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

RX_MOUSE
NC score	0.001991 (rank : 73)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	429	Shared Neighborhood Hits	4
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

CNTN1_HUMAN
NC score	0.001509 (rank : 74)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	431	Shared Neighborhood Hits	2
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

ZN486_HUMAN
NC score	-0.000282 (rank : 75)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	645	Shared Neighborhood Hits	3
SwissProt Accessions	Q96H40	Gene names	ZNF486, KRBO2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 486.

ZN253_HUMAN
NC score	-0.000627 (rank : 76)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	711	Shared Neighborhood Hits	4
SwissProt Accessions	O75346	Gene names	ZNF253, BMZF1
Domain Architecture
Description	Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1).