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Network neighborhood for query Sequence : AB1IP_MOUSE

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AB1IP_MOUSE
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AB1IP_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

AB1IP_HUMAN
θ value	4.11024e-170 (rank : 2)	NC score	0.951245 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	213	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

RAPH1_HUMAN
θ value	2.00813e-108 (rank : 3)	NC score	0.803550 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	593	Shared Neighborhood Hits	101
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GRB14_HUMAN
θ value	2.50074e-42 (rank : 4)	NC score	0.699253 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	18
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB10_HUMAN
θ value	1.98146e-39 (rank : 5)	NC score	0.730791 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	1.98146e-39 (rank : 6)	NC score	0.732497 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_MOUSE
θ value	1.6774e-38 (rank : 7)	NC score	0.683682 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	4.72714e-33 (rank : 8)	NC score	0.705824 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	6.38894e-30 (rank : 9)	NC score	0.686599 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	157	Shared Neighborhood Hits	17
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

RGS3_MOUSE
θ value	0.000270298 (rank : 10)	NC score	0.108063 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	1621	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MAGE1_HUMAN
θ value	0.000602161 (rank : 11)	NC score	0.094145 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	1389	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CEL_HUMAN
θ value	0.000786445 (rank : 12)	NC score	0.093159 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CEND1_HUMAN
θ value	0.00298849 (rank : 13)	NC score	0.098360 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	284	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

FA47B_HUMAN
θ value	0.00298849 (rank : 14)	NC score	0.141608 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

AATK_HUMAN
θ value	0.00390308 (rank : 15)	NC score	0.028639 (rank : 297)
Query Neighborhood Hits	181	Target Neighborhood Hits	1243	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

NFH_MOUSE
θ value	0.00869519 (rank : 16)	NC score	0.062468 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	2247	Shared Neighborhood Hits	84
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LCP2_HUMAN
θ value	0.0113563 (rank : 17)	NC score	0.126057 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	531	Shared Neighborhood Hits	51
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ZN687_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.034708 (rank : 283)
Query Neighborhood Hits	181	Target Neighborhood Hits	1244	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

F120C_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.077058 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

NACAM_MOUSE
θ value	0.0193708 (rank : 20)	NC score	0.115596 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	1866	Shared Neighborhood Hits	97
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MILK1_MOUSE
θ value	0.0252991 (rank : 21)	NC score	0.082042 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	788	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SON_HUMAN
θ value	0.0252991 (rank : 22)	NC score	0.098381 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	1568	Shared Neighborhood Hits	90
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FA47A_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.154411 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	451	Shared Neighborhood Hits	59
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

TXND2_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.092904 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CEND1_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.074162 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

RGS3_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.088063 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	1375	Shared Neighborhood Hits	71
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GA2L2_MOUSE
θ value	0.0736092 (rank : 27)	NC score	0.083689 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	395	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

IF4G1_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.058681 (rank : 202)
Query Neighborhood Hits	181	Target Neighborhood Hits	534	Shared Neighborhood Hits	38
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PCLO_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.093556 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	2046	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ECM1_MOUSE
θ value	0.125558 (rank : 30)	NC score	0.078362 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

OGFR_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.065607 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	584	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

RPGF1_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.050638 (rank : 253)
Query Neighborhood Hits	181	Target Neighborhood Hits	262	Shared Neighborhood Hits	20
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

ZIM10_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.074963 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	577	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	0.125558 (rank : 34)	NC score	0.061522 (rank : 189)
Query Neighborhood Hits	181	Target Neighborhood Hits	430	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

K1543_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.089154 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	497	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CEND2_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.055793 (rank : 217)
Query Neighborhood Hits	181	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

GAB1_MOUSE
θ value	0.21417 (rank : 37)	NC score	0.089254 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	233	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

NPAS4_MOUSE
θ value	0.21417 (rank : 38)	NC score	0.055991 (rank : 215)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

TROAP_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.097436 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	258	Shared Neighborhood Hits	31
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

IASPP_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.042453 (rank : 270)
Query Neighborhood Hits	181	Target Neighborhood Hits	1024	Shared Neighborhood Hits	62
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

UBQL2_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.028658 (rank : 296)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

BAG3_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.085440 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

F120C_HUMAN
θ value	0.365318 (rank : 43)	NC score	0.062662 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

AIRE_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.041235 (rank : 273)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CO039_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.070557 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MLL3_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.070699 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	1644	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NSD1_MOUSE
θ value	0.47712 (rank : 47)	NC score	0.046215 (rank : 265)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SMR2C_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.073902 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	O35985	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform gamma precursor (Salivary protein MSG2, isoform gamma).

SMR2D_MOUSE
θ value	0.47712 (rank : 49)	NC score	0.075234 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O35979	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform delta precursor (Salivary protein MSG2, isoform delta).

SPR1B_MOUSE
θ value	0.47712 (rank : 50)	NC score	0.070206 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	395	Shared Neighborhood Hits	32
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

ZN710_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.002217 (rank : 355)
Query Neighborhood Hits	181	Target Neighborhood Hits	796	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

BCL9_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.080851 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	1008	Shared Neighborhood Hits	72
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

GAB1_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.078373 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

IGHG1_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.011025 (rank : 337)
Query Neighborhood Hits	181	Target Neighborhood Hits	229	Shared Neighborhood Hits	2
SwissProt Accessions	P01857	Gene names	IGHG1
Domain Architecture
Description	Ig gamma-1 chain C region.

IQGA3_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.024087 (rank : 305)
Query Neighborhood Hits	181	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

LPP_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.047115 (rank : 264)
Query Neighborhood Hits	181	Target Neighborhood Hits	775	Shared Neighborhood Hits	50
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PSL1_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.061925 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RERE_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.097083 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.095443 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	785	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

UB7I3_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.026977 (rank : 301)
Query Neighborhood Hits	181	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

ZN516_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.014375 (rank : 327)
Query Neighborhood Hits	181	Target Neighborhood Hits	1197	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CNKR2_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.074095 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.074152 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH3_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.072671 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

DACH1_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.032082 (rank : 291)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

FMN2_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.076084 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	349	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

HCLS1_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.038753 (rank : 278)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	28
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

INP5E_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.038164 (rank : 280)
Query Neighborhood Hits	181	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

PKN3_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.005869 (rank : 351)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

URP2_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.039971 (rank : 275)
Query Neighborhood Hits	181	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

ACK1_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.025391 (rank : 303)
Query Neighborhood Hits	181	Target Neighborhood Hits	1140	Shared Neighborhood Hits	64
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CASP_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.019784 (rank : 315)
Query Neighborhood Hits	181	Target Neighborhood Hits	1131	Shared Neighborhood Hits	21
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.029586 (rank : 295)
Query Neighborhood Hits	181	Target Neighborhood Hits	1574	Shared Neighborhood Hits	44
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CYH3_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.076596 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

DCC_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.020843 (rank : 312)
Query Neighborhood Hits	181	Target Neighborhood Hits	896	Shared Neighborhood Hits	34
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

FGD5_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.019539 (rank : 316)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

K1802_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.082299 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	1596	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TULP4_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.054605 (rank : 228)
Query Neighborhood Hits	181	Target Neighborhood Hits	426	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

CASP_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.019865 (rank : 314)
Query Neighborhood Hits	181	Target Neighborhood Hits	1152	Shared Neighborhood Hits	21
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CD2_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.061857 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	504	Shared Neighborhood Hits	34
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

GAK5_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.053265 (rank : 236)
Query Neighborhood Hits	181	Target Neighborhood Hits	429	Shared Neighborhood Hits	36
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MYO5A_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.011175 (rank : 336)
Query Neighborhood Hits	181	Target Neighborhood Hits	1117	Shared Neighborhood Hits	27
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

PRRT3_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.089191 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	998	Shared Neighborhood Hits	74
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ACK1_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.020368 (rank : 313)
Query Neighborhood Hits	181	Target Neighborhood Hits	1080	Shared Neighborhood Hits	56
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ANK2_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.027302 (rank : 300)
Query Neighborhood Hits	181	Target Neighborhood Hits	1615	Shared Neighborhood Hits	60
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CD008_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.033986 (rank : 285)
Query Neighborhood Hits	181	Target Neighborhood Hits	330	Shared Neighborhood Hits	16
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CYH1_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.076536 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.076903 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	176	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.074802 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	1.81305 (rank : 90)	NC score	0.073932 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	171	Shared Neighborhood Hits	28
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

EAN57_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.029927 (rank : 294)
Query Neighborhood Hits	181	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

GAK11_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.051929 (rank : 244)
Query Neighborhood Hits	181	Target Neighborhood Hits	409	Shared Neighborhood Hits	36
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.051161 (rank : 249)
Query Neighborhood Hits	181	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.052152 (rank : 243)
Query Neighborhood Hits	181	Target Neighborhood Hits	415	Shared Neighborhood Hits	37
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GLIS3_MOUSE
θ value	1.81305 (rank : 95)	NC score	0.005742 (rank : 352)
Query Neighborhood Hits	181	Target Neighborhood Hits	861	Shared Neighborhood Hits	29
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

MYH9_MOUSE
θ value	1.81305 (rank : 96)	NC score	0.008816 (rank : 345)
Query Neighborhood Hits	181	Target Neighborhood Hits	1829	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SPR1A_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.055363 (rank : 220)
Query Neighborhood Hits	181	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TCGAP_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.062419 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	872	Shared Neighborhood Hits	58
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BAZ2A_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.033601 (rank : 287)
Query Neighborhood Hits	181	Target Neighborhood Hits	744	Shared Neighborhood Hits	44
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CUTL1_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.032593 (rank : 288)
Query Neighborhood Hits	181	Target Neighborhood Hits	1620	Shared Neighborhood Hits	41
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYH4_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.063961 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.068678 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

FGF21_MOUSE
θ value	2.36792 (rank : 103)	NC score	0.017746 (rank : 321)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJN1	Gene names	Fgf21
Domain Architecture
Description	Fibroblast growth factor 21 precursor (FGF-21).

GLTL1_MOUSE
θ value	2.36792 (rank : 104)	NC score	0.013962 (rank : 328)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JJ61	Gene names	Galntl1
Domain Architecture	No domain graphic available
Description	Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase- like protein 1) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1).

MDC1_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.076606 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SC24C_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.061206 (rank : 192)
Query Neighborhood Hits	181	Target Neighborhood Hits	662	Shared Neighborhood Hits	46
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SCNNB_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.013077 (rank : 331)
Query Neighborhood Hits	181	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

SEPT9_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.045818 (rank : 267)
Query Neighborhood Hits	181	Target Neighborhood Hits	706	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SETX_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.022968 (rank : 309)
Query Neighborhood Hits	181	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

TARSH_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.106313 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	768	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

URP2_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.032299 (rank : 289)
Query Neighborhood Hits	181	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

BCAR1_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.055343 (rank : 222)
Query Neighborhood Hits	181	Target Neighborhood Hits	554	Shared Neighborhood Hits	51
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CJ108_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.048945 (rank : 263)
Query Neighborhood Hits	181	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CSTF2_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.009211 (rank : 344)
Query Neighborhood Hits	181	Target Neighborhood Hits	296	Shared Neighborhood Hits	13
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

CTGE4_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.017859 (rank : 320)
Query Neighborhood Hits	181	Target Neighborhood Hits	393	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

GALT1_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.012922 (rank : 332)
Query Neighborhood Hits	181	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q10472, Q86TJ7, Q9UM86	Gene names	GALNT1
Domain Architecture
Description	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) [Contains: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form].

K1543_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.070955 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	435	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.075641 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

M3K5_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.002519 (rank : 354)
Query Neighborhood Hits	181	Target Neighborhood Hits	868	Shared Neighborhood Hits	12
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

MILK2_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.041533 (rank : 272)
Query Neighborhood Hits	181	Target Neighborhood Hits	457	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

OBSCN_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.009485 (rank : 342)
Query Neighborhood Hits	181	Target Neighborhood Hits	1931	Shared Neighborhood Hits	60
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PCLO_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.080004 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	2275	Shared Neighborhood Hits	108
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TXLNB_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.021473 (rank : 311)
Query Neighborhood Hits	181	Target Neighborhood Hits	640	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

CO039_MOUSE
θ value	4.03905 (rank : 124)	NC score	0.076496 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	445	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DGKH_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.028481 (rank : 298)
Query Neighborhood Hits	181	Target Neighborhood Hits	255	Shared Neighborhood Hits	24
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ELL_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.023620 (rank : 307)
Query Neighborhood Hits	181	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ELL_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.030203 (rank : 293)
Query Neighborhood Hits	181	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

GALT5_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.012920 (rank : 333)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C102	Gene names	Galnt5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

INVS_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.012295 (rank : 335)
Query Neighborhood Hits	181	Target Neighborhood Hits	609	Shared Neighborhood Hits	28
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

LARP4_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.039613 (rank : 276)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MTSS1_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.049834 (rank : 261)
Query Neighborhood Hits	181	Target Neighborhood Hits	504	Shared Neighborhood Hits	30
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MYO15_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.034144 (rank : 284)
Query Neighborhood Hits	181	Target Neighborhood Hits	671	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OGFR_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.085635 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	1582	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ALMS1_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.018413 (rank : 318)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ASPP1_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.045462 (rank : 268)
Query Neighborhood Hits	181	Target Neighborhood Hits	1244	Shared Neighborhood Hits	64
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATF6B_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.017116 (rank : 322)
Query Neighborhood Hits	181	Target Neighborhood Hits	122	Shared Neighborhood Hits	12
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BSN_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.083958 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	2057	Shared Neighborhood Hits	105
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CI047_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.026906 (rank : 302)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZRZ4, Q5SQD7, Q7Z568, Q8N1V4	Gene names	C9orf47
Domain Architecture	No domain graphic available
Description	Protein C9orf47 precursor.

EDD1_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.009802 (rank : 341)
Query Neighborhood Hits	181	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

ERBB2_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.006452 (rank : 349)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	24
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

GAK7_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.036487 (rank : 282)
Query Neighborhood Hits	181	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

GGA1_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.015543 (rank : 326)
Query Neighborhood Hits	181	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

INVO_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.023423 (rank : 308)
Query Neighborhood Hits	181	Target Neighborhood Hits	636	Shared Neighborhood Hits	19
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

KSR2_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.007531 (rank : 346)
Query Neighborhood Hits	181	Target Neighborhood Hits	920	Shared Neighborhood Hits	31
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

LCP2_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.072496 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	177	Shared Neighborhood Hits	23
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LNX2_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.004867 (rank : 353)
Query Neighborhood Hits	181	Target Neighborhood Hits	407	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PI3R4_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.010528 (rank : 340)
Query Neighborhood Hits	181	Target Neighborhood Hits	535	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

SOX3_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.006938 (rank : 347)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

TACC3_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.016066 (rank : 325)
Query Neighborhood Hits	181	Target Neighborhood Hits	607	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TCF7_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.013313 (rank : 329)
Query Neighborhood Hits	181	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TRI66_MOUSE
θ value	5.27518 (rank : 151)	NC score	0.033923 (rank : 286)
Query Neighborhood Hits	181	Target Neighborhood Hits	491	Shared Neighborhood Hits	47
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WNK1_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.006493 (rank : 348)
Query Neighborhood Hits	181	Target Neighborhood Hits	1179	Shared Neighborhood Hits	35
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZN710_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.001222 (rank : 356)
Query Neighborhood Hits	181	Target Neighborhood Hits	749	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U288, Q3U341, Q6P9R3, Q8BJH0, Q8BTL6	Gene names	Znf710, Zfp710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ATBF1_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.017945 (rank : 319)
Query Neighborhood Hits	181	Target Neighborhood Hits	1547	Shared Neighborhood Hits	63
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CC036_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.024028 (rank : 306)
Query Neighborhood Hits	181	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q3SXR2, Q3SXR3, Q9H6K8	Gene names	C3orf36
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf36.

DLG5_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.018845 (rank : 317)
Query Neighborhood Hits	181	Target Neighborhood Hits	1088	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GALT5_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.013170 (rank : 330)
Query Neighborhood Hits	181	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

MAP4_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.066746 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	428	Shared Neighborhood Hits	45
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAVS_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.041139 (rank : 274)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

OTU7B_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.010726 (rank : 338)
Query Neighborhood Hits	181	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

PHLB1_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.042361 (rank : 271)
Query Neighborhood Hits	181	Target Neighborhood Hits	1038	Shared Neighborhood Hits	67
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TPO_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.032217 (rank : 290)
Query Neighborhood Hits	181	Target Neighborhood Hits	258	Shared Neighborhood Hits	19
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

ARNT_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.006180 (rank : 350)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARRD1_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.009301 (rank : 343)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ATN1_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.103598 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	676	Shared Neighborhood Hits	73
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CEBPE_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.010607 (rank : 339)
Query Neighborhood Hits	181	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CTGE6_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.016388 (rank : 324)
Query Neighborhood Hits	181	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

GAK12_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.049024 (rank : 262)
Query Neighborhood Hits	181	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

K0310_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.065233 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	420	Shared Neighborhood Hits	47
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAGD4_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.024441 (rank : 304)
Query Neighborhood Hits	181	Target Neighborhood Hits	338	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MTSS1_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.046081 (rank : 266)
Query Neighborhood Hits	181	Target Neighborhood Hits	592	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PHLB1_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.039304 (rank : 277)
Query Neighborhood Hits	181	Target Neighborhood Hits	678	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PLEK_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.028349 (rank : 299)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PSD4_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.042946 (rank : 269)
Query Neighborhood Hits	181	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

RAD21_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.012577 (rank : 334)
Query Neighborhood Hits	181	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q61550, P70219, Q91VB9, Q9DBU4	Gene names	Rad21, Hr21
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog).

RC3H1_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.038325 (rank : 279)
Query Neighborhood Hits	181	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RHG25_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.030305 (rank : 292)
Query Neighborhood Hits	181	Target Neighborhood Hits	550	Shared Neighborhood Hits	34
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.037738 (rank : 281)
Query Neighborhood Hits	181	Target Neighborhood Hits	492	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIMS1_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.022432 (rank : 310)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SFPQ_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.071870 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	958	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SPEG_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.017048 (rank : 323)
Query Neighborhood Hits	181	Target Neighborhood Hits	1762	Shared Neighborhood Hits	83
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

3BP1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.054143 (rank : 234)
Query Neighborhood Hits	181	Target Neighborhood Hits	376	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.054553 (rank : 230)
Query Neighborhood Hits	181	Target Neighborhood Hits	296	Shared Neighborhood Hits	35
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ALEX_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.070280 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.052183 (rank : 242)
Query Neighborhood Hits	181	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

APS_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.074947 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.066414 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

BAG3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.059540 (rank : 197)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	49
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.062637 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	321	Shared Neighborhood Hits	33
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.063643 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.079196 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	931	Shared Neighborhood Hits	92
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.069436 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	947	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCAR3_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.075680 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.077365 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCL9_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.066398 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	770	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BLNK_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.065530 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	296	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BRD4_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.062061 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	851	Shared Neighborhood Hits	85
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.064670 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	845	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BSN_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.070329 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	1537	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CBP_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.058841 (rank : 200)
Query Neighborhood Hits	181	Target Neighborhood Hits	941	Shared Neighborhood Hits	76
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.055420 (rank : 219)
Query Neighborhood Hits	181	Target Neighborhood Hits	1051	Shared Neighborhood Hits	81
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCNK_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.070246 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	350	Shared Neighborhood Hits	75
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.050717 (rank : 252)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	34
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CIC_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.054303 (rank : 232)
Query Neighborhood Hits	181	Target Neighborhood Hits	992	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ078_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.084420 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	559	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.065399 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.076939 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.068574 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	233	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.087767 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CPSF6_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.074553 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	359	Shared Neighborhood Hits	59
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.075925 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	356	Shared Neighborhood Hits	61
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRKL_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.072061 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	313	Shared Neighborhood Hits	11
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.069372 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.082179 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	308	Shared Neighborhood Hits	13
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.080739 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	14
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRTC1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.065090 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	319	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS007_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.050405 (rank : 255)
Query Neighborhood Hits	181	Target Neighborhood Hits	464	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.089036 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DAPP1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.068188 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.064529 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DGKK_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.059375 (rank : 199)
Query Neighborhood Hits	181	Target Neighborhood Hits	378	Shared Neighborhood Hits	61
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

EFS_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.052821 (rank : 237)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	39
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

ENAH_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.074285 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	919	Shared Neighborhood Hits	93
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.054874 (rank : 226)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	83
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FMN1A_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.057829 (rank : 209)
Query Neighborhood Hits	181	Target Neighborhood Hits	423	Shared Neighborhood Hits	63
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.063258 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	447	Shared Neighborhood Hits	68
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.066696 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	484	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.061813 (rank : 188)
Query Neighborhood Hits	181	Target Neighborhood Hits	529	Shared Neighborhood Hits	83
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GGN_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.069416 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	269	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.068674 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	311	Shared Neighborhood Hits	57
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRAP2_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.073022 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	304	Shared Neighborhood Hits	12
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.066452 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	297	Shared Neighborhood Hits	12
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.075357 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	16
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.072419 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	309	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.061504 (rank : 191)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	14
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.061508 (rank : 190)
Query Neighborhood Hits	181	Target Neighborhood Hits	312	Shared Neighborhood Hits	14
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GSCR1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.088810 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	674	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HSH2D_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.063711 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.075713 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IQEC2_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.054831 (rank : 227)
Query Neighborhood Hits	181	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

K1802_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.065884 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	1378	Shared Neighborhood Hits	80
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LNK_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.073400 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	151	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.087630 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MADCA_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.054556 (rank : 229)
Query Neighborhood Hits	181	Target Neighborhood Hits	221	Shared Neighborhood Hits	40
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MARCS_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.056099 (rank : 213)
Query Neighborhood Hits	181	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MBD6_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.082807 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.071675 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	1446	Shared Neighborhood Hits	77
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MILK1_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.052720 (rank : 238)
Query Neighborhood Hits	181	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.050366 (rank : 257)
Query Neighborhood Hits	181	Target Neighborhood Hits	1514	Shared Neighborhood Hits	81
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MISS_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.079247 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	444	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.070300 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	1788	Shared Neighborhood Hits	109
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.062156 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	1399	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL4_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.066788 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	722	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MNT_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.064201 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	496	Shared Neighborhood Hits	68
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.056093 (rank : 214)
Query Neighborhood Hits	181	Target Neighborhood Hits	432	Shared Neighborhood Hits	59
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MUC1_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.080795 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	975	Shared Neighborhood Hits	62
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC2_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.054880 (rank : 225)
Query Neighborhood Hits	181	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.090973 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	538	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.051335 (rank : 247)
Query Neighborhood Hits	181	Target Neighborhood Hits	777	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCK1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.072263 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	312	Shared Neighborhood Hits	14
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.068939 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	14
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOA6_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.064961 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	1202	Shared Neighborhood Hits	88
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.059531 (rank : 198)
Query Neighborhood Hits	181	Target Neighborhood Hits	1076	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NUMBL_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.052275 (rank : 241)
Query Neighborhood Hits	181	Target Neighborhood Hits	394	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PELP1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.058449 (rank : 203)
Query Neighborhood Hits	181	Target Neighborhood Hits	596	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.054477 (rank : 231)
Query Neighborhood Hits	181	Target Neighborhood Hits	709	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PLCG1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.066556 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	293	Shared Neighborhood Hits	15
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.066634 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	15
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.063060 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PO121_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.050186 (rank : 259)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRB3_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.100628 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	318	Shared Neighborhood Hits	59
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.104735 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	330	Shared Neighborhood Hits	58
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.086740 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	764	Shared Neighborhood Hits	76
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.081549 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	624	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.110143 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	385	Shared Neighborhood Hits	67
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.120504 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	347	Shared Neighborhood Hits	64
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.062046 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.066170 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR12_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.121571 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	460	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.069060 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.051646 (rank : 246)
Query Neighborhood Hits	181	Target Neighborhood Hits	54	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PS1C2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.071375 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.058797 (rank : 201)
Query Neighborhood Hits	181	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN11_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.051069 (rank : 251)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.051076 (rank : 250)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

RASA1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.085223 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RIN2_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.077593 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN2_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.088507 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN3_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.064136 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.067017 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	239	Shared Neighborhood Hits	61
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SC24A_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.051763 (rank : 245)
Query Neighborhood Hits	181	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SELPL_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.055078 (rank : 224)
Query Neighborhood Hits	181	Target Neighborhood Hits	588	Shared Neighborhood Hits	48
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.056229 (rank : 211)
Query Neighborhood Hits	181	Target Neighborhood Hits	118	Shared Neighborhood Hits	29
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.064881 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	690	Shared Neighborhood Hits	83
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.062530 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	287	Shared Neighborhood Hits	66
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.055572 (rank : 218)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.083872 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	263	Shared Neighborhood Hits	63
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.084611 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	58
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.071089 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	986	Shared Neighborhood Hits	87
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFR15_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.057963 (rank : 207)
Query Neighborhood Hits	181	Target Neighborhood Hits	368	Shared Neighborhood Hits	54
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.050312 (rank : 258)
Query Neighborhood Hits	181	Target Neighborhood Hits	180	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SH21A_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.100792 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.094899 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.105358 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.077302 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.103305 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.111101 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH2D3_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.051280 (rank : 248)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.057855 (rank : 208)
Query Neighborhood Hits	181	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHC1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.070336 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.067528 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.089162 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.089420 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.075302 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.079127 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.050390 (rank : 256)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.052543 (rank : 240)
Query Neighborhood Hits	181	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SLAP2_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.060418 (rank : 194)
Query Neighborhood Hits	181	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.050152 (rank : 260)
Query Neighborhood Hits	181	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SMR1_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.101488 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	44
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.076991 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SMR3B_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.060075 (rank : 195)
Query Neighborhood Hits	181	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SON_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.082342 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	957	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRRM1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.098322 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	690	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.083966 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	966	Shared Neighborhood Hits	76
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.064318 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	1296	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.061879 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	1470	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYN1_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.057964 (rank : 206)
Query Neighborhood Hits	181	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.050551 (rank : 254)
Query Neighborhood Hits	181	Target Neighborhood Hits	363	Shared Neighborhood Hits	57
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.057993 (rank : 205)
Query Neighborhood Hits	181	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.059981 (rank : 196)
Query Neighborhood Hits	181	Target Neighborhood Hits	516	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T22D2_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.058264 (rank : 204)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	47
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAF4_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.084960 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	687	Shared Neighborhood Hits	74
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TENS4_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.055277 (rank : 223)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TM108_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.054266 (rank : 233)
Query Neighborhood Hits	181	Target Neighborhood Hits	336	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

VCY1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.052679 (rank : 239)
Query Neighborhood Hits	181	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

WASF1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.056248 (rank : 210)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.055349 (rank : 221)
Query Neighborhood Hits	181	Target Neighborhood Hits	261	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.071912 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	280	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.072393 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	315	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF4_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.070142 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	282	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.113513 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	80
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.115689 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	392	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.078493 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.083385 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	339	Shared Neighborhood Hits	69
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.065097 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	55
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.056213 (rank : 212)
Query Neighborhood Hits	181	Target Neighborhood Hits	223	Shared Neighborhood Hits	50
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.085051 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	354	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.082283 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	362	Shared Neighborhood Hits	66
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.053281 (rank : 235)
Query Neighborhood Hits	181	Target Neighborhood Hits	273	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.101791 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	329	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.094447 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.060663 (rank : 193)
Query Neighborhood Hits	181	Target Neighborhood Hits	670	Shared Neighborhood Hits	70
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.076095 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	505	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZIMP7_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.055990 (rank : 216)
Query Neighborhood Hits	181	Target Neighborhood Hits	566	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN207_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.068156 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	326	Shared Neighborhood Hits	40
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

AB1IP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

AB1IP_HUMAN
NC score	0.951245 (rank : 2)	θ value	4.11024e-170 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	213	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

RAPH1_HUMAN
NC score	0.803550 (rank : 3)	θ value	2.00813e-108 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	593	Shared Neighborhood Hits	101
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GRB10_MOUSE
NC score	0.732497 (rank : 4)	θ value	1.98146e-39 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB10_HUMAN
NC score	0.730791 (rank : 5)	θ value	1.98146e-39 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB7_HUMAN
NC score	0.705824 (rank : 6)	θ value	4.72714e-33 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB14_HUMAN
NC score	0.699253 (rank : 7)	θ value	2.50074e-42 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	18
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_MOUSE
NC score	0.686599 (rank : 8)	θ value	6.38894e-30 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	157	Shared Neighborhood Hits	17
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRB14_MOUSE
NC score	0.683682 (rank : 9)	θ value	1.6774e-38 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

FA47A_HUMAN
NC score	0.154411 (rank : 10)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	451	Shared Neighborhood Hits	59
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
NC score	0.141608 (rank : 11)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

LCP2_HUMAN
NC score	0.126057 (rank : 12)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	531	Shared Neighborhood Hits	51
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PRR12_HUMAN
NC score	0.121571 (rank : 13)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	181	Target Neighborhood Hits	460	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRP2_MOUSE
NC score	0.120504 (rank : 14)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	181	Target Neighborhood Hits	347	Shared Neighborhood Hits	64
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

WASIP_MOUSE
NC score	0.115689 (rank : 15)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	181	Target Neighborhood Hits	392	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

NACAM_MOUSE
NC score	0.115596 (rank : 16)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	1866	Shared Neighborhood Hits	97
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WASIP_HUMAN
NC score	0.113513 (rank : 17)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	80
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SH22A_MOUSE
NC score	0.111101 (rank : 18)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	181	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

PRP1_HUMAN
NC score	0.110143 (rank : 19)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	181	Target Neighborhood Hits	385	Shared Neighborhood Hits	67
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RGS3_MOUSE
NC score	0.108063 (rank : 20)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	1621	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TARSH_HUMAN
NC score	0.106313 (rank : 21)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	768	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SH21B_HUMAN
NC score	0.105358 (rank : 22)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

PRB4S_HUMAN
NC score	0.104735 (rank : 23)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	181	Target Neighborhood Hits	330	Shared Neighborhood Hits	58
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ATN1_HUMAN
NC score	0.103598 (rank : 24)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	676	Shared Neighborhood Hits	73
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SH22A_HUMAN
NC score	0.103305 (rank : 25)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

WIRE_HUMAN
NC score	0.101791 (rank : 26)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	181	Target Neighborhood Hits	329	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SMR1_MOUSE
NC score	0.101488 (rank : 27)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	44
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SH21A_HUMAN
NC score	0.100792 (rank : 28)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

PRB3_HUMAN
NC score	0.100628 (rank : 29)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	181	Target Neighborhood Hits	318	Shared Neighborhood Hits	59
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SON_HUMAN
NC score	0.098381 (rank : 30)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	1568	Shared Neighborhood Hits	90
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CEND1_HUMAN
NC score	0.098360 (rank : 31)	θ value	0.00298849 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	284	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

SRRM1_HUMAN
NC score	0.098322 (rank : 32)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	181	Target Neighborhood Hits	690	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TROAP_HUMAN
NC score	0.097436 (rank : 33)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	258	Shared Neighborhood Hits	31
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

RERE_HUMAN
NC score	0.097083 (rank : 34)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
NC score	0.095443 (rank : 35)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	785	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SH21A_MOUSE
NC score	0.094899 (rank : 36)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

WIRE_MOUSE
NC score	0.094447 (rank : 37)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MAGE1_HUMAN
NC score	0.094145 (rank : 38)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	1389	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PCLO_HUMAN
NC score	0.093556 (rank : 39)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	2046	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CEL_HUMAN
NC score	0.093159 (rank : 40)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TXND2_HUMAN
NC score	0.092904 (rank : 41)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MUC7_HUMAN
NC score	0.090973 (rank : 42)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	181	Target Neighborhood Hits	538	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SHC2_MOUSE
NC score	0.089420 (rank : 43)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

GAB1_MOUSE
NC score	0.089254 (rank : 44)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	233	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PRRT3_HUMAN
NC score	0.089191 (rank : 45)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	998	Shared Neighborhood Hits	74
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SHC2_HUMAN
NC score	0.089162 (rank : 46)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

K1543_MOUSE
NC score	0.089154 (rank : 47)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	497	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CS016_HUMAN
NC score	0.089036 (rank : 48)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

GSCR1_HUMAN
NC score	0.088810 (rank : 49)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	181	Target Neighborhood Hits	674	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

RIN2_MOUSE
NC score	0.088507 (rank : 50)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	181	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RGS3_HUMAN
NC score	0.088063 (rank : 51)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	1375	Shared Neighborhood Hits	71
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CN155_HUMAN
NC score	0.087767 (rank : 52)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	181	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

LNK_MOUSE
NC score	0.087630 (rank : 53)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	181	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

PRG4_HUMAN
NC score	0.086740 (rank : 54)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	181	Target Neighborhood Hits	764	Shared Neighborhood Hits	76
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

OGFR_HUMAN
NC score	0.085635 (rank : 55)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	1582	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BAG3_MOUSE
NC score	0.085440 (rank : 56)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

RASA1_HUMAN
NC score	0.085223 (rank : 57)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	181	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

WBP11_HUMAN
NC score	0.085051 (rank : 58)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	181	Target Neighborhood Hits	354	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

TAF4_HUMAN
NC score	0.084960 (rank : 59)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	181	Target Neighborhood Hits	687	Shared Neighborhood Hits	74
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SF3A2_MOUSE
NC score	0.084611 (rank : 60)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	58
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CJ078_MOUSE
NC score	0.084420 (rank : 61)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	181	Target Neighborhood Hits	559	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SRRM1_MOUSE
NC score	0.083966 (rank : 62)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	181	Target Neighborhood Hits	966	Shared Neighborhood Hits	76
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BSN_MOUSE
NC score	0.083958 (rank : 63)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	2057	Shared Neighborhood Hits	105
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SF3A2_HUMAN
NC score	0.083872 (rank : 64)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	181	Target Neighborhood Hits	263	Shared Neighborhood Hits	63
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

GA2L2_MOUSE
NC score	0.083689 (rank : 65)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	395	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

WASL_MOUSE
NC score	0.083385 (rank : 66)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	181	Target Neighborhood Hits	339	Shared Neighborhood Hits	69
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MBD6_HUMAN
NC score	0.082807 (rank : 67)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	181	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

SON_MOUSE
NC score	0.082342 (rank : 68)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	181	Target Neighborhood Hits	957	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

K1802_MOUSE
NC score	0.082299 (rank : 69)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	1596	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WBP11_MOUSE
NC score	0.082283 (rank : 70)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	181	Target Neighborhood Hits	362	Shared Neighborhood Hits	66
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

CRK_HUMAN
NC score	0.082179 (rank : 71)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	181	Target Neighborhood Hits	308	Shared Neighborhood Hits	13
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

MILK1_MOUSE
NC score	0.082042 (rank : 72)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	788	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PRG4_MOUSE
NC score	0.081549 (rank : 73)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	181	Target Neighborhood Hits	624	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

BCL9_HUMAN
NC score	0.080851 (rank : 74)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	1008	Shared Neighborhood Hits	72
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MUC1_HUMAN
NC score	0.080795 (rank : 75)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	181	Target Neighborhood Hits	975	Shared Neighborhood Hits	62
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CRK_MOUSE
NC score	0.080739 (rank : 76)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	14
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PCLO_MOUSE
NC score	0.080004 (rank : 77)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	2275	Shared Neighborhood Hits	108
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MISS_MOUSE
NC score	0.079247 (rank : 78)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	181	Target Neighborhood Hits	444	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

BAT2_HUMAN
NC score	0.079196 (rank : 79)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	181	Target Neighborhood Hits	931	Shared Neighborhood Hits	92
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SHC3_MOUSE
NC score	0.079127 (rank : 80)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	181	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

WASL_HUMAN
NC score	0.078493 (rank : 81)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	181	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

GAB1_HUMAN
NC score	0.078373 (rank : 82)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

ECM1_MOUSE
NC score	0.078362 (rank : 83)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

RIN2_HUMAN
NC score	0.077593 (rank : 84)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	181	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

BCAR3_MOUSE
NC score	0.077365 (rank : 85)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	181	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

SH21B_MOUSE
NC score	0.077302 (rank : 86)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

F120C_MOUSE
NC score	0.077058 (rank : 87)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

SMR3A_HUMAN
NC score	0.076991 (rank : 88)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

CN032_HUMAN
NC score	0.076939 (rank : 89)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	181	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CYH1_MOUSE
NC score	0.076903 (rank : 90)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	176	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

MDC1_MOUSE
NC score	0.076606 (rank : 91)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CYH3_HUMAN
NC score	0.076596 (rank : 92)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
NC score	0.076536 (rank : 93)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CO039_MOUSE
NC score	0.076496 (rank : 94)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	445	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

YLPM1_MOUSE
NC score	0.076095 (rank : 95)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	181	Target Neighborhood Hits	505	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

FMN2_MOUSE
NC score	0.076084 (rank : 96)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	349	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

CPSF6_MOUSE
NC score	0.075925 (rank : 97)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	181	Target Neighborhood Hits	356	Shared Neighborhood Hits	61
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

HSH2D_MOUSE
NC score	0.075713 (rank : 98)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	181	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

BCAR3_HUMAN
NC score	0.075680 (rank : 99)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	181	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

K1683_HUMAN
NC score	0.075641 (rank : 100)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

GRAP_HUMAN
NC score	0.075357 (rank : 101)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	16
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SHC3_HUMAN
NC score	0.075302 (rank : 102)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	181	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SMR2D_MOUSE
NC score	0.075234 (rank : 103)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O35979	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform delta precursor (Salivary protein MSG2, isoform delta).

ZIM10_HUMAN
NC score	0.074963 (rank : 104)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	577	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

APS_HUMAN
NC score	0.074947 (rank : 105)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CYH2_HUMAN
NC score	0.074802 (rank : 106)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CPSF6_HUMAN
NC score	0.074553 (rank : 107)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	181	Target Neighborhood Hits	359	Shared Neighborhood Hits	59
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

ENAH_MOUSE
NC score	0.074285 (rank : 108)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	181	Target Neighborhood Hits	919	Shared Neighborhood Hits	93
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CEND1_MOUSE
NC score	0.074162 (rank : 109)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CNKR2_MOUSE
NC score	0.074152 (rank : 110)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.074095 (rank : 111)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH2_MOUSE
NC score	0.073932 (rank : 112)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	171	Shared Neighborhood Hits	28
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

SMR2C_MOUSE
NC score	0.073902 (rank : 113)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	O35985	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform gamma precursor (Salivary protein MSG2, isoform gamma).

LNK_HUMAN
NC score	0.073400 (rank : 114)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	181	Target Neighborhood Hits	151	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

GRAP2_HUMAN
NC score	0.073022 (rank : 115)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	181	Target Neighborhood Hits	304	Shared Neighborhood Hits	12
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

CYH3_MOUSE
NC score	0.072671 (rank : 116)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

LCP2_MOUSE
NC score	0.072496 (rank : 117)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	177	Shared Neighborhood Hits	23
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

GRAP_MOUSE
NC score	0.072419 (rank : 118)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	181	Target Neighborhood Hits	309	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

WASF2_MOUSE
NC score	0.072393 (rank : 119)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	181	Target Neighborhood Hits	315	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

NCK1_HUMAN
NC score	0.072263 (rank : 120)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	181	Target Neighborhood Hits	312	Shared Neighborhood Hits	14
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

CRKL_HUMAN
NC score	0.072061 (rank : 121)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	181	Target Neighborhood Hits	313	Shared Neighborhood Hits	11
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

WASF2_HUMAN
NC score	0.071912 (rank : 122)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	181	Target Neighborhood Hits	280	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

SFPQ_MOUSE
NC score	0.071870 (rank : 123)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	958	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

MDC1_HUMAN
NC score	0.071675 (rank : 124)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	181	Target Neighborhood Hits	1446	Shared Neighborhood Hits	77
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PS1C2_HUMAN
NC score	0.071375 (rank : 125)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

SFPQ_HUMAN
NC score	0.071089 (rank : 126)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	181	Target Neighborhood Hits	986	Shared Neighborhood Hits	87
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

K1543_HUMAN
NC score	0.070955 (rank : 127)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	435	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MLL3_HUMAN
NC score	0.070699 (rank : 128)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	1644	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CO039_HUMAN
NC score	0.070557 (rank : 129)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

SHC1_HUMAN
NC score	0.070336 (rank : 130)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

BSN_HUMAN
NC score	0.070329 (rank : 131)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	181	Target Neighborhood Hits	1537	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MLL2_HUMAN
NC score	0.070300 (rank : 132)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	181	Target Neighborhood Hits	1788	Shared Neighborhood Hits	109
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ALEX_HUMAN
NC score	0.070280 (rank : 133)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CCNK_MOUSE
NC score	0.070246 (rank : 134)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	181	Target Neighborhood Hits	350	Shared Neighborhood Hits	75
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

SPR1B_MOUSE
NC score	0.070206 (rank : 135)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	395	Shared Neighborhood Hits	32
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

WASF4_HUMAN
NC score	0.070142 (rank : 136)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	181	Target Neighborhood Hits	282	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

BAT2_MOUSE
NC score	0.069436 (rank : 137)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	181	Target Neighborhood Hits	947	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GGN_HUMAN
NC score	0.069416 (rank : 138)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	181	Target Neighborhood Hits	269	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CRKL_MOUSE
NC score	0.069372 (rank : 139)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

PRR13_HUMAN
NC score	0.069060 (rank : 140)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

NCK2_HUMAN
NC score	0.068939 (rank : 141)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	14
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CYH4_MOUSE
NC score	0.068678 (rank : 142)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

GGN_MOUSE
NC score	0.068674 (rank : 143)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	181	Target Neighborhood Hits	311	Shared Neighborhood Hits	57
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CN032_MOUSE
NC score	0.068574 (rank : 144)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	181	Target Neighborhood Hits	233	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

DAPP1_HUMAN
NC score	0.068188 (rank : 145)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ZN207_HUMAN
NC score	0.068156 (rank : 146)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	181	Target Neighborhood Hits	326	Shared Neighborhood Hits	40
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

SHC1_MOUSE
NC score	0.067528 (rank : 147)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	181	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

RIN3_MOUSE
NC score	0.067017 (rank : 148)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	181	Target Neighborhood Hits	239	Shared Neighborhood Hits	61
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MLL4_HUMAN
NC score	0.066788 (rank : 149)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	181	Target Neighborhood Hits	722	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MAP4_HUMAN
NC score	0.066746 (rank : 150)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	428	Shared Neighborhood Hits	45
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

FMN2_HUMAN
NC score	0.066696 (rank : 151)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	181	Target Neighborhood Hits	484	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PLCG1_MOUSE
NC score	0.066634 (rank : 152)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	15
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_HUMAN
NC score	0.066556 (rank : 153)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	181	Target Neighborhood Hits	293	Shared Neighborhood Hits	15
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

GRAP2_MOUSE
NC score	0.066452 (rank : 154)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	181	Target Neighborhood Hits	297	Shared Neighborhood Hits	12
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

APS_MOUSE
NC score	0.066414 (rank : 155)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

BCL9_MOUSE
NC score	0.066398 (rank : 156)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	181	Target Neighborhood Hits	770	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PRPC_HUMAN
NC score	0.066170 (rank : 157)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	181	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

K1802_HUMAN
NC score	0.065884 (rank : 158)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	181	Target Neighborhood Hits	1378	Shared Neighborhood Hits	80
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

OGFR_MOUSE
NC score	0.065607 (rank : 159)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	584	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

BLNK_MOUSE
NC score	0.065530 (rank : 160)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	181	Target Neighborhood Hits	296	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CK024_HUMAN
NC score	0.065399 (rank : 161)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	181	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

K0310_HUMAN
NC score	0.065233 (rank : 162)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	420	Shared Neighborhood Hits	47
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

WASP_HUMAN
NC score	0.065097 (rank : 163)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	55
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

CRTC1_HUMAN
NC score	0.065090 (rank : 164)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	181	Target Neighborhood Hits	319	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

NCOA6_HUMAN
NC score	0.064961 (rank : 165)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	181	Target Neighborhood Hits	1202	Shared Neighborhood Hits	88
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SET1A_HUMAN
NC score	0.064881 (rank : 166)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	181	Target Neighborhood Hits	690	Shared Neighborhood Hits	83
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

BRD4_MOUSE
NC score	0.064670 (rank : 167)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	181	Target Neighborhood Hits	845	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

DAPP1_MOUSE
NC score	0.064529 (rank : 168)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SRRM2_HUMAN
NC score	0.064318 (rank : 169)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	181	Target Neighborhood Hits	1296	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MNT_HUMAN
NC score	0.064201 (rank : 170)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	181	Target Neighborhood Hits	496	Shared Neighborhood Hits	68
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RIN3_HUMAN
NC score	0.064136 (rank : 171)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CYH4_HUMAN
NC score	0.063961 (rank : 172)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

HSH2D_HUMAN
NC score	0.063711 (rank : 173)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	181	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

BASP_MOUSE
NC score	0.063643 (rank : 174)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

FMN1B_MOUSE
NC score	0.063258 (rank : 175)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	181	Target Neighborhood Hits	447	Shared Neighborhood Hits	68
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

PLCG2_HUMAN
NC score	0.063060 (rank : 176)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	181	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

F120C_HUMAN
NC score	0.062662 (rank : 177)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

BASP_HUMAN
NC score	0.062637 (rank : 178)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	181	Target Neighborhood Hits	321	Shared Neighborhood Hits	33
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SF01_HUMAN
NC score	0.062530 (rank : 179)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	181	Target Neighborhood Hits	287	Shared Neighborhood Hits	66
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

NFH_MOUSE
NC score	0.062468 (rank : 180)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	2247	Shared Neighborhood Hits	84
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCGAP_HUMAN
NC score	0.062419 (rank : 181)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	872	Shared Neighborhood Hits	58
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MLL3_MOUSE
NC score	0.062156 (rank : 182)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	181	Target Neighborhood Hits	1399	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BRD4_HUMAN
NC score	0.062061 (rank : 183)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	181	Target Neighborhood Hits	851	Shared Neighborhood Hits	85
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

PRP5_HUMAN
NC score	0.062046 (rank : 184)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	181	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PSL1_HUMAN
NC score	0.061925 (rank : 185)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SRRM2_MOUSE
NC score	0.061879 (rank : 186)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	181	Target Neighborhood Hits	1470	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CD2_HUMAN
NC score	0.061857 (rank : 187)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	504	Shared Neighborhood Hits	34
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

FMNL_HUMAN
NC score	0.061813 (rank : 188)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	181	Target Neighborhood Hits	529	Shared Neighborhood Hits	83
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ZIM10_MOUSE
NC score	0.061522 (rank : 189)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	430	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

GRB2_MOUSE
NC score	0.061508 (rank : 190)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	181	Target Neighborhood Hits	312	Shared Neighborhood Hits	14
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRB2_HUMAN
NC score	0.061504 (rank : 191)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	14
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

SC24C_HUMAN
NC score	0.061206 (rank : 192)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	662	Shared Neighborhood Hits	46
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

YLPM1_HUMAN
NC score	0.060663 (rank : 193)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	181	Target Neighborhood Hits	670	Shared Neighborhood Hits	70
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SLAP2_HUMAN
NC score	0.060418 (rank : 194)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	181	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SMR3B_HUMAN
NC score	0.060075 (rank : 195)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	181	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SYNJ1_MOUSE
NC score	0.059981 (rank : 196)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	181	Target Neighborhood Hits	516	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BAG3_HUMAN
NC score	0.059540 (rank : 197)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	49
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

NCOA6_MOUSE
NC score	0.059531 (rank : 198)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	181	Target Neighborhood Hits	1076	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DGKK_HUMAN
NC score	0.059375 (rank : 199)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	181	Target Neighborhood Hits	378	Shared Neighborhood Hits	61
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

CBP_HUMAN
NC score	0.058841 (rank : 200)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	181	Target Neighborhood Hits	941	Shared Neighborhood Hits	76
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PS1C2_MOUSE
NC score	0.058797 (rank : 201)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	181	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

IF4G1_MOUSE
NC score	0.058681 (rank : 202)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	534	Shared Neighborhood Hits	38
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PELP1_HUMAN
NC score	0.058449 (rank : 203)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	181	Target Neighborhood Hits	596	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

T22D2_HUMAN
NC score	0.058264 (rank : 204)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	47
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SYNJ1_HUMAN
NC score	0.057993 (rank : 205)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	181	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYN1_HUMAN
NC score	0.057964 (rank : 206)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	181	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SFR15_HUMAN
NC score	0.057963 (rank : 207)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	181	Target Neighborhood Hits	368	Shared Neighborhood Hits	54
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH2D3_MOUSE
NC score	0.057855 (rank : 208)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	181	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

FMN1A_MOUSE
NC score	0.057829 (rank : 209)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	181	Target Neighborhood Hits	423	Shared Neighborhood Hits	63
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

WASF1_HUMAN
NC score	0.056248 (rank : 210)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

SELV_HUMAN
NC score	0.056229 (rank : 211)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	181	Target Neighborhood Hits	118	Shared Neighborhood Hits	29
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

WASP_MOUSE
NC score	0.056213 (rank : 212)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	181	Target Neighborhood Hits	223	Shared Neighborhood Hits	50
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

MARCS_HUMAN
NC score	0.056099 (rank : 213)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	181	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MNT_MOUSE
NC score	0.056093 (rank : 214)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	181	Target Neighborhood Hits	432	Shared Neighborhood Hits	59
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NPAS4_MOUSE
NC score	0.055991 (rank : 215)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

ZIMP7_MOUSE
NC score	0.055990 (rank : 216)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	181	Target Neighborhood Hits	566	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CEND2_HUMAN
NC score	0.055793 (rank : 217)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SF01_MOUSE
NC score	0.055572 (rank : 218)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

CBP_MOUSE
NC score	0.055420 (rank : 219)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	181	Target Neighborhood Hits	1051	Shared Neighborhood Hits	81
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SPR1A_MOUSE
NC score	0.055363 (rank : 220)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

WASF1_MOUSE
NC score	0.055349 (rank : 221)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	181	Target Neighborhood Hits	261	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

BCAR1_HUMAN
NC score	0.055343 (rank : 222)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	554	Shared Neighborhood Hits	51
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

TENS4_HUMAN
NC score	0.055277 (rank : 223)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

SELPL_MOUSE
NC score	0.055078 (rank : 224)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	181	Target Neighborhood Hits	588	Shared Neighborhood Hits	48
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MUC2_HUMAN
NC score	0.054880 (rank : 225)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	181	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

EP300_HUMAN
NC score	0.054874 (rank : 226)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	83
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

IQEC2_MOUSE
NC score	0.054831 (rank : 227)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	181	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

TULP4_HUMAN
NC score	0.054605 (rank : 228)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	426	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MADCA_HUMAN
NC score	0.054556 (rank : 229)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	181	Target Neighborhood Hits	221	Shared Neighborhood Hits	40
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

3BP2_HUMAN
NC score	0.054553 (rank : 230)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	296	Shared Neighborhood Hits	35
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PELP1_MOUSE
NC score	0.054477 (rank : 231)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	181	Target Neighborhood Hits	709	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

CIC_HUMAN
NC score	0.054303 (rank : 232)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	181	Target Neighborhood Hits	992	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TM108_MOUSE
NC score	0.054266 (rank : 233)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	181	Target Neighborhood Hits	336	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

3BP1_HUMAN
NC score	0.054143 (rank : 234)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	376	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

WBS14_HUMAN
NC score	0.053281 (rank : 235)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	181	Target Neighborhood Hits	273	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

GAK5_HUMAN
NC score	0.053265 (rank : 236)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	429	Shared Neighborhood Hits	36
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

EFS_HUMAN
NC score	0.052821 (rank : 237)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	39
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

MILK1_HUMAN
NC score	0.052720 (rank : 238)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	181	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

VCY1_HUMAN
NC score	0.052679 (rank : 239)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	181	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

SHE_MOUSE
NC score	0.052543 (rank : 240)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	181	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

NUMBL_HUMAN
NC score	0.052275 (rank : 241)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	181	Target Neighborhood Hits	394	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

ALEX_MOUSE
NC score	0.052183 (rank : 242)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GAK4_HUMAN
NC score	0.052152 (rank : 243)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	415	Shared Neighborhood Hits	37
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.051929 (rank : 244)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	409	Shared Neighborhood Hits	36
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SC24A_MOUSE
NC score	0.051763 (rank : 245)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	181	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

PRR13_MOUSE
NC score	0.051646 (rank : 246)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	181	Target Neighborhood Hits	54	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

MUCDL_HUMAN
NC score	0.051335 (rank : 247)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	181	Target Neighborhood Hits	777	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SH2D3_HUMAN
NC score	0.051280 (rank : 248)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

GAK2_HUMAN
NC score	0.051161 (rank : 249)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PTN11_MOUSE
NC score	0.051076 (rank : 250)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.051069 (rank : 251)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

CDN1C_HUMAN
NC score	0.050717 (rank : 252)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	34
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

RPGF1_HUMAN
NC score	0.050638 (rank : 253)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	262	Shared Neighborhood Hits	20
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SYN1_MOUSE
NC score	0.050551 (rank : 254)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	181	Target Neighborhood Hits	363	Shared Neighborhood Hits	57
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CS007_MOUSE
NC score	0.050405 (rank : 255)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	181	Target Neighborhood Hits	464	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SHD_MOUSE
NC score	0.050390 (rank : 256)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

MINT_MOUSE
NC score	0.050366 (rank : 257)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	181	Target Neighborhood Hits	1514	Shared Neighborhood Hits	81
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SGIP1_MOUSE
NC score	0.050312 (rank : 258)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	181	Target Neighborhood Hits	180	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

PO121_HUMAN
NC score	0.050186 (rank : 259)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SLAP2_MOUSE
NC score	0.050152 (rank : 260)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	181	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

MTSS1_HUMAN
NC score	0.049834 (rank : 261)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	504	Shared Neighborhood Hits	30
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

GAK12_HUMAN
NC score	0.049024 (rank : 262)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CJ108_HUMAN
NC score	0.048945 (rank : 263)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

LPP_HUMAN
NC score	0.047115 (rank : 264)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	775	Shared Neighborhood Hits	50
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

NSD1_MOUSE
NC score	0.046215 (rank : 265)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MTSS1_MOUSE
NC score	0.046081 (rank : 266)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	592	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SEPT9_HUMAN
NC score	0.045818 (rank : 267)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	706	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ASPP1_MOUSE
NC score	0.045462 (rank : 268)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	1244	Shared Neighborhood Hits	64
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PSD4_HUMAN
NC score	0.042946 (rank : 269)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

IASPP_MOUSE
NC score	0.042453 (rank : 270)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	1024	Shared Neighborhood Hits	62
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PHLB1_HUMAN
NC score	0.042361 (rank : 271)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	1038	Shared Neighborhood Hits	67
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MILK2_HUMAN
NC score	0.041533 (rank : 272)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	457	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

AIRE_MOUSE
NC score	0.041235 (rank : 273)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MAVS_HUMAN
NC score	0.041139 (rank : 274)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

URP2_HUMAN
NC score	0.039971 (rank : 275)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

LARP4_MOUSE
NC score	0.039613 (rank : 276)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PHLB1_MOUSE
NC score	0.039304 (rank : 277)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	678	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

HCLS1_HUMAN
NC score	0.038753 (rank : 278)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	28
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

RC3H1_HUMAN
NC score	0.038325 (rank : 279)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

INP5E_HUMAN
NC score	0.038164 (rank : 280)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

RHG25_MOUSE
NC score	0.037738 (rank : 281)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	492	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

GAK7_HUMAN
NC score	0.036487 (rank : 282)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

ZN687_HUMAN
NC score	0.034708 (rank : 283)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	1244	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MYO15_HUMAN
NC score	0.034144 (rank : 284)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	671	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CD008_HUMAN
NC score	0.033986 (rank : 285)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	330	Shared Neighborhood Hits	16
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

TRI66_MOUSE
NC score	0.033923 (rank : 286)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	491	Shared Neighborhood Hits	47
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BAZ2A_MOUSE
NC score	0.033601 (rank : 287)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	744	Shared Neighborhood Hits	44
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CUTL1_MOUSE
NC score	0.032593 (rank : 288)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	1620	Shared Neighborhood Hits	41
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

URP2_MOUSE
NC score	0.032299 (rank : 289)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

TPO_MOUSE
NC score	0.032217 (rank : 290)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	258	Shared Neighborhood Hits	19
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

DACH1_HUMAN
NC score	0.032082 (rank : 291)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

RHG25_HUMAN
NC score	0.030305 (rank : 292)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	550	Shared Neighborhood Hits	34
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

ELL_MOUSE
NC score	0.030203 (rank : 293)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

EAN57_HUMAN
NC score	0.029927 (rank : 294)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

CUTL1_HUMAN
NC score	0.029586 (rank : 295)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	1574	Shared Neighborhood Hits	44
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

UBQL2_HUMAN
NC score	0.028658 (rank : 296)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

AATK_HUMAN
NC score	0.028639 (rank : 297)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	1243	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

DGKH_HUMAN
NC score	0.028481 (rank : 298)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	255	Shared Neighborhood Hits	24
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

PLEK_HUMAN
NC score	0.028349 (rank : 299)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

ANK2_HUMAN
NC score	0.027302 (rank : 300)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	1615	Shared Neighborhood Hits	60
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

UB7I3_HUMAN
NC score	0.026977 (rank : 301)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

CI047_HUMAN
NC score	0.026906 (rank : 302)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZRZ4, Q5SQD7, Q7Z568, Q8N1V4	Gene names	C9orf47
Domain Architecture	No domain graphic available
Description	Protein C9orf47 precursor.

ACK1_HUMAN
NC score	0.025391 (rank : 303)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	1140	Shared Neighborhood Hits	64
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

MAGD4_HUMAN
NC score	0.024441 (rank : 304)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	338	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

IQGA3_HUMAN
NC score	0.024087 (rank : 305)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

CC036_HUMAN
NC score	0.024028 (rank : 306)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q3SXR2, Q3SXR3, Q9H6K8	Gene names	C3orf36
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf36.

ELL_HUMAN
NC score	0.023620 (rank : 307)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

INVO_HUMAN
NC score	0.023423 (rank : 308)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	636	Shared Neighborhood Hits	19
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

SETX_HUMAN
NC score	0.022968 (rank : 309)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

RIMS1_HUMAN
NC score	0.022432 (rank : 310)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TXLNB_MOUSE
NC score	0.021473 (rank : 311)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	640	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

DCC_MOUSE
NC score	0.020843 (rank : 312)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	896	Shared Neighborhood Hits	34
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ACK1_MOUSE
NC score	0.020368 (rank : 313)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	1080	Shared Neighborhood Hits	56
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CASP_MOUSE
NC score	0.019865 (rank : 314)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	1152	Shared Neighborhood Hits	21
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
NC score	0.019784 (rank : 315)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	1131	Shared Neighborhood Hits	21
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

FGD5_MOUSE
NC score	0.019539 (rank : 316)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

DLG5_HUMAN
NC score	0.018845 (rank : 317)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	1088	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

ALMS1_MOUSE
NC score	0.018413 (rank : 318)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ATBF1_HUMAN
NC score	0.017945 (rank : 319)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	1547	Shared Neighborhood Hits	63
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CTGE4_HUMAN
NC score	0.017859 (rank : 320)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	393	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

FGF21_MOUSE
NC score	0.017746 (rank : 321)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJN1	Gene names	Fgf21
Domain Architecture
Description	Fibroblast growth factor 21 precursor (FGF-21).

ATF6B_HUMAN
NC score	0.017116 (rank : 322)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	122	Shared Neighborhood Hits	12
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

SPEG_HUMAN
NC score	0.017048 (rank : 323)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	1762	Shared Neighborhood Hits	83
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CTGE6_HUMAN
NC score	0.016388 (rank : 324)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

TACC3_MOUSE
NC score	0.016066 (rank : 325)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	607	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

GGA1_MOUSE
NC score	0.015543 (rank : 326)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

ZN516_MOUSE
NC score	0.014375 (rank : 327)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	1197	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

GLTL1_MOUSE
NC score	0.013962 (rank : 328)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JJ61	Gene names	Galntl1
Domain Architecture	No domain graphic available
Description	Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase- like protein 1) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1).

TCF7_MOUSE
NC score	0.013313 (rank : 329)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

GALT5_HUMAN
NC score	0.013170 (rank : 330)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

SCNNB_HUMAN
NC score	0.013077 (rank : 331)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

GALT1_HUMAN
NC score	0.012922 (rank : 332)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q10472, Q86TJ7, Q9UM86	Gene names	GALNT1
Domain Architecture
Description	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) [Contains: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form].

GALT5_MOUSE
NC score	0.012920 (rank : 333)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C102	Gene names	Galnt5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

RAD21_MOUSE
NC score	0.012577 (rank : 334)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q61550, P70219, Q91VB9, Q9DBU4	Gene names	Rad21, Hr21
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog).

INVS_MOUSE
NC score	0.012295 (rank : 335)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	609	Shared Neighborhood Hits	28
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MYO5A_MOUSE
NC score	0.011175 (rank : 336)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	1117	Shared Neighborhood Hits	27
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

IGHG1_HUMAN
NC score	0.011025 (rank : 337)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	229	Shared Neighborhood Hits	2
SwissProt Accessions	P01857	Gene names	IGHG1
Domain Architecture
Description	Ig gamma-1 chain C region.

OTU7B_HUMAN
NC score	0.010726 (rank : 338)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

CEBPE_HUMAN
NC score	0.010607 (rank : 339)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

PI3R4_MOUSE
NC score	0.010528 (rank : 340)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	535	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

EDD1_MOUSE
NC score	0.009802 (rank : 341)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

OBSCN_HUMAN
NC score	0.009485 (rank : 342)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	1931	Shared Neighborhood Hits	60
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ARRD1_HUMAN
NC score	0.009301 (rank : 343)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CSTF2_HUMAN
NC score	0.009211 (rank : 344)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	296	Shared Neighborhood Hits	13
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

MYH9_MOUSE
NC score	0.008816 (rank : 345)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	1829	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

KSR2_HUMAN
NC score	0.007531 (rank : 346)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	920	Shared Neighborhood Hits	31
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

SOX3_HUMAN
NC score	0.006938 (rank : 347)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

WNK1_MOUSE
NC score	0.006493 (rank : 348)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	1179	Shared Neighborhood Hits	35
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ERBB2_HUMAN
NC score	0.006452 (rank : 349)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	24
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ARNT_HUMAN
NC score	0.006180 (rank : 350)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

PKN3_MOUSE
NC score	0.005869 (rank : 351)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

GLIS3_MOUSE
NC score	0.005742 (rank : 352)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	861	Shared Neighborhood Hits	29
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

LNX2_MOUSE
NC score	0.004867 (rank : 353)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	407	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

M3K5_HUMAN
NC score	0.002519 (rank : 354)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	868	Shared Neighborhood Hits	12
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

ZN710_HUMAN
NC score	0.002217 (rank : 355)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	796	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZN710_MOUSE
NC score	0.001222 (rank : 356)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	749	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U288, Q3U341, Q6P9R3, Q8BJH0, Q8BTL6	Gene names	Znf710, Zfp710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.