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Network neighborhood for query Sequence : RAPH1_HUMAN

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RAPH1_HUMAN
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RAPH1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	593	Target Neighborhood Hits	593	Shared Neighborhood Hits	593
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

AB1IP_HUMAN
θ value	7.37397e-111 (rank : 2)	NC score	0.822430 (rank : 2)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
θ value	2.00813e-108 (rank : 3)	NC score	0.803550 (rank : 3)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	101
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

GRB14_HUMAN
θ value	2.19075e-38 (rank : 4)	NC score	0.552818 (rank : 7)
Query Neighborhood Hits	593	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	7.04741e-37 (rank : 5)	NC score	0.541135 (rank : 9)
Query Neighborhood Hits	593	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB10_HUMAN
θ value	9.20422e-37 (rank : 6)	NC score	0.580603 (rank : 4)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	5.584e-34 (rank : 7)	NC score	0.578610 (rank : 5)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB7_HUMAN
θ value	5.584e-34 (rank : 8)	NC score	0.559578 (rank : 6)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	2.59387e-31 (rank : 9)	NC score	0.545645 (rank : 8)
Query Neighborhood Hits	593	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

MUC1_HUMAN
θ value	3.88503e-19 (rank : 10)	NC score	0.226951 (rank : 61)
Query Neighborhood Hits	593	Target Neighborhood Hits	975	Shared Neighborhood Hits	201
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NACAM_MOUSE
θ value	5.43371e-13 (rank : 11)	NC score	0.320426 (rank : 18)
Query Neighborhood Hits	593	Target Neighborhood Hits	1866	Shared Neighborhood Hits	373
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFH_MOUSE
θ value	3.89403e-11 (rank : 12)	NC score	0.167373 (rank : 135)
Query Neighborhood Hits	593	Target Neighborhood Hits	2247	Shared Neighborhood Hits	306
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

K1802_MOUSE
θ value	5.08577e-11 (rank : 13)	NC score	0.216006 (rank : 72)
Query Neighborhood Hits	593	Target Neighborhood Hits	1596	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAGE1_HUMAN
θ value	5.62301e-10 (rank : 14)	NC score	0.200905 (rank : 90)
Query Neighborhood Hits	593	Target Neighborhood Hits	1389	Shared Neighborhood Hits	281
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MDC1_HUMAN
θ value	1.06045e-08 (rank : 15)	NC score	0.276766 (rank : 30)
Query Neighborhood Hits	593	Target Neighborhood Hits	1446	Shared Neighborhood Hits	280
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PCLO_HUMAN
θ value	8.97725e-08 (rank : 16)	NC score	0.269141 (rank : 31)
Query Neighborhood Hits	593	Target Neighborhood Hits	2046	Shared Neighborhood Hits	378
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MLL3_MOUSE
θ value	3.41135e-07 (rank : 17)	NC score	0.188208 (rank : 104)
Query Neighborhood Hits	593	Target Neighborhood Hits	1399	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MDC1_MOUSE
θ value	4.45536e-07 (rank : 18)	NC score	0.267162 (rank : 32)
Query Neighborhood Hits	593	Target Neighborhood Hits	998	Shared Neighborhood Hits	226
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SON_HUMAN
θ value	9.92553e-07 (rank : 19)	NC score	0.240071 (rank : 50)
Query Neighborhood Hits	593	Target Neighborhood Hits	1568	Shared Neighborhood Hits	292
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CEL_HUMAN
θ value	1.29631e-06 (rank : 20)	NC score	0.143880 (rank : 191)
Query Neighborhood Hits	593	Target Neighborhood Hits	896	Shared Neighborhood Hits	178
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ZN438_HUMAN
θ value	1.69304e-06 (rank : 21)	NC score	0.049903 (rank : 847)
Query Neighborhood Hits	593	Target Neighborhood Hits	906	Shared Neighborhood Hits	99
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

FA47A_HUMAN
θ value	3.77169e-06 (rank : 22)	NC score	0.240292 (rank : 49)
Query Neighborhood Hits	593	Target Neighborhood Hits	451	Shared Neighborhood Hits	129
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

RGS3_MOUSE
θ value	4.92598e-06 (rank : 23)	NC score	0.213123 (rank : 77)
Query Neighborhood Hits	593	Target Neighborhood Hits	1621	Shared Neighborhood Hits	287
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CD248_HUMAN
θ value	8.40245e-06 (rank : 24)	NC score	0.118168 (rank : 266)
Query Neighborhood Hits	593	Target Neighborhood Hits	679	Shared Neighborhood Hits	147
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

NUMBL_HUMAN
θ value	8.40245e-06 (rank : 25)	NC score	0.146565 (rank : 183)
Query Neighborhood Hits	593	Target Neighborhood Hits	394	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TARSH_HUMAN
θ value	1.09739e-05 (rank : 26)	NC score	0.282109 (rank : 27)
Query Neighborhood Hits	593	Target Neighborhood Hits	768	Shared Neighborhood Hits	206
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MLL3_HUMAN
θ value	3.19293e-05 (rank : 27)	NC score	0.208024 (rank : 86)
Query Neighborhood Hits	593	Target Neighborhood Hits	1644	Shared Neighborhood Hits	282
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PRRT3_HUMAN
θ value	3.19293e-05 (rank : 28)	NC score	0.228089 (rank : 60)
Query Neighborhood Hits	593	Target Neighborhood Hits	998	Shared Neighborhood Hits	224
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

K1802_HUMAN
θ value	5.44631e-05 (rank : 29)	NC score	0.223324 (rank : 63)
Query Neighborhood Hits	593	Target Neighborhood Hits	1378	Shared Neighborhood Hits	283
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RGS3_HUMAN
θ value	7.1131e-05 (rank : 30)	NC score	0.154341 (rank : 156)
Query Neighborhood Hits	593	Target Neighborhood Hits	1375	Shared Neighborhood Hits	232
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CEND1_HUMAN
θ value	9.29e-05 (rank : 31)	NC score	0.085777 (rank : 450)
Query Neighborhood Hits	593	Target Neighborhood Hits	284	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

PHC2_HUMAN
θ value	9.29e-05 (rank : 32)	NC score	0.154086 (rank : 157)
Query Neighborhood Hits	593	Target Neighborhood Hits	388	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

LPP_HUMAN
θ value	0.000121331 (rank : 33)	NC score	0.128760 (rank : 231)
Query Neighborhood Hits	593	Target Neighborhood Hits	775	Shared Neighborhood Hits	164
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

OGFR_HUMAN
θ value	0.000121331 (rank : 34)	NC score	0.204024 (rank : 88)
Query Neighborhood Hits	593	Target Neighborhood Hits	1582	Shared Neighborhood Hits	257
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CAC1G_HUMAN
θ value	0.000270298 (rank : 35)	NC score	0.066736 (rank : 612)
Query Neighborhood Hits	593	Target Neighborhood Hits	587	Shared Neighborhood Hits	116
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TXND2_HUMAN
θ value	0.000270298 (rank : 36)	NC score	0.176087 (rank : 122)
Query Neighborhood Hits	593	Target Neighborhood Hits	793	Shared Neighborhood Hits	148
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

NUP53_MOUSE
θ value	0.00035302 (rank : 37)	NC score	0.125060 (rank : 241)
Query Neighborhood Hits	593	Target Neighborhood Hits	94	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

SON_MOUSE
θ value	0.00035302 (rank : 38)	NC score	0.229018 (rank : 58)
Query Neighborhood Hits	593	Target Neighborhood Hits	957	Shared Neighborhood Hits	211
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

JPH2_HUMAN
θ value	0.000602161 (rank : 39)	NC score	0.107961 (rank : 310)
Query Neighborhood Hits	593	Target Neighborhood Hits	639	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NUP53_HUMAN
θ value	0.000602161 (rank : 40)	NC score	0.132369 (rank : 223)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

DCC_MOUSE
θ value	0.000786445 (rank : 41)	NC score	0.051296 (rank : 829)
Query Neighborhood Hits	593	Target Neighborhood Hits	896	Shared Neighborhood Hits	124
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

PER2_MOUSE
θ value	0.000786445 (rank : 42)	NC score	0.073003 (rank : 537)
Query Neighborhood Hits	593	Target Neighborhood Hits	325	Shared Neighborhood Hits	65
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

LCP2_HUMAN
θ value	0.00102713 (rank : 43)	NC score	0.192219 (rank : 98)
Query Neighborhood Hits	593	Target Neighborhood Hits	531	Shared Neighborhood Hits	159
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

NCOA6_HUMAN
θ value	0.00102713 (rank : 44)	NC score	0.224846 (rank : 62)
Query Neighborhood Hits	593	Target Neighborhood Hits	1202	Shared Neighborhood Hits	291
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SPR1B_MOUSE
θ value	0.00102713 (rank : 45)	NC score	0.143010 (rank : 194)
Query Neighborhood Hits	593	Target Neighborhood Hits	395	Shared Neighborhood Hits	94
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

FA47B_HUMAN
θ value	0.00134147 (rank : 46)	NC score	0.208457 (rank : 85)
Query Neighborhood Hits	593	Target Neighborhood Hits	431	Shared Neighborhood Hits	127
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GAK2_HUMAN
θ value	0.00134147 (rank : 47)	NC score	0.151678 (rank : 168)
Query Neighborhood Hits	593	Target Neighborhood Hits	406	Shared Neighborhood Hits	100
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MAP4_HUMAN
θ value	0.00134147 (rank : 48)	NC score	0.199082 (rank : 91)
Query Neighborhood Hits	593	Target Neighborhood Hits	428	Shared Neighborhood Hits	119
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

GAK11_HUMAN
θ value	0.00175202 (rank : 49)	NC score	0.152550 (rank : 164)
Query Neighborhood Hits	593	Target Neighborhood Hits	409	Shared Neighborhood Hits	104
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	0.00175202 (rank : 50)	NC score	0.148622 (rank : 176)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	93
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.00175202 (rank : 51)	NC score	0.153058 (rank : 162)
Query Neighborhood Hits	593	Target Neighborhood Hits	415	Shared Neighborhood Hits	104
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	0.00175202 (rank : 52)	NC score	0.153561 (rank : 160)
Query Neighborhood Hits	593	Target Neighborhood Hits	429	Shared Neighborhood Hits	105
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.00175202 (rank : 53)	NC score	0.148145 (rank : 178)
Query Neighborhood Hits	593	Target Neighborhood Hits	392	Shared Neighborhood Hits	101
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LR37A_HUMAN
θ value	0.00175202 (rank : 54)	NC score	0.135618 (rank : 215)
Query Neighborhood Hits	593	Target Neighborhood Hits	720	Shared Neighborhood Hits	157
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ZN217_HUMAN
θ value	0.00175202 (rank : 55)	NC score	0.026624 (rank : 957)
Query Neighborhood Hits	593	Target Neighborhood Hits	905	Shared Neighborhood Hits	85
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

CBP_MOUSE
θ value	0.00228821 (rank : 56)	NC score	0.210901 (rank : 82)
Query Neighborhood Hits	593	Target Neighborhood Hits	1051	Shared Neighborhood Hits	273
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GAB1_HUMAN
θ value	0.00228821 (rank : 57)	NC score	0.131673 (rank : 226)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	87
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GNAS1_MOUSE
θ value	0.00298849 (rank : 58)	NC score	0.098701 (rank : 364)
Query Neighborhood Hits	593	Target Neighborhood Hits	651	Shared Neighborhood Hits	147
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K1683_HUMAN
θ value	0.00298849 (rank : 59)	NC score	0.158855 (rank : 147)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SEPT9_HUMAN
θ value	0.00298849 (rank : 60)	NC score	0.099391 (rank : 357)
Query Neighborhood Hits	593	Target Neighborhood Hits	706	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ANK2_HUMAN
θ value	0.00390308 (rank : 61)	NC score	0.091300 (rank : 410)
Query Neighborhood Hits	593	Target Neighborhood Hits	1615	Shared Neighborhood Hits	233
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BCAR1_HUMAN
θ value	0.00509761 (rank : 62)	NC score	0.149128 (rank : 173)
Query Neighborhood Hits	593	Target Neighborhood Hits	554	Shared Neighborhood Hits	142
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BSN_MOUSE
θ value	0.00509761 (rank : 63)	NC score	0.249863 (rank : 42)
Query Neighborhood Hits	593	Target Neighborhood Hits	2057	Shared Neighborhood Hits	348
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CT032_HUMAN
θ value	0.00509761 (rank : 64)	NC score	0.101172 (rank : 343)
Query Neighborhood Hits	593	Target Neighborhood Hits	235	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ERRFI_MOUSE
θ value	0.00509761 (rank : 65)	NC score	0.106168 (rank : 322)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

RTKN_HUMAN
θ value	0.00509761 (rank : 66)	NC score	0.099491 (rank : 355)
Query Neighborhood Hits	593	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

TCF8_HUMAN
θ value	0.00509761 (rank : 67)	NC score	0.020688 (rank : 997)
Query Neighborhood Hits	593	Target Neighborhood Hits	1057	Shared Neighborhood Hits	63
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TCGAP_HUMAN
θ value	0.00509761 (rank : 68)	NC score	0.126214 (rank : 238)
Query Neighborhood Hits	593	Target Neighborhood Hits	872	Shared Neighborhood Hits	179
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TGON2_HUMAN
θ value	0.00509761 (rank : 69)	NC score	0.151126 (rank : 169)
Query Neighborhood Hits	593	Target Neighborhood Hits	1037	Shared Neighborhood Hits	167
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

GA2L2_MOUSE
θ value	0.00665767 (rank : 70)	NC score	0.129974 (rank : 228)
Query Neighborhood Hits	593	Target Neighborhood Hits	395	Shared Neighborhood Hits	116
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

JADE2_MOUSE
θ value	0.00665767 (rank : 71)	NC score	0.089831 (rank : 417)
Query Neighborhood Hits	593	Target Neighborhood Hits	560	Shared Neighborhood Hits	127
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

NUMBL_MOUSE
θ value	0.00665767 (rank : 72)	NC score	0.114165 (rank : 281)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	42
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

PCLO_MOUSE
θ value	0.00665767 (rank : 73)	NC score	0.242877 (rank : 46)
Query Neighborhood Hits	593	Target Neighborhood Hits	2275	Shared Neighborhood Hits	380
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SC24C_HUMAN
θ value	0.00665767 (rank : 74)	NC score	0.166994 (rank : 136)
Query Neighborhood Hits	593	Target Neighborhood Hits	662	Shared Neighborhood Hits	152
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SSBP4_HUMAN
θ value	0.00665767 (rank : 75)	NC score	0.108177 (rank : 308)
Query Neighborhood Hits	593	Target Neighborhood Hits	753	Shared Neighborhood Hits	149
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TM108_MOUSE
θ value	0.00665767 (rank : 76)	NC score	0.183607 (rank : 111)
Query Neighborhood Hits	593	Target Neighborhood Hits	336	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

EFS_HUMAN
θ value	0.00869519 (rank : 77)	NC score	0.152462 (rank : 165)
Query Neighborhood Hits	593	Target Neighborhood Hits	348	Shared Neighborhood Hits	102
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FOXN1_HUMAN
θ value	0.00869519 (rank : 78)	NC score	0.058205 (rank : 719)
Query Neighborhood Hits	593	Target Neighborhood Hits	377	Shared Neighborhood Hits	75
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GAB1_MOUSE
θ value	0.00869519 (rank : 79)	NC score	0.131895 (rank : 225)
Query Neighborhood Hits	593	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

NOTC2_MOUSE
θ value	0.00869519 (rank : 80)	NC score	0.033649 (rank : 923)
Query Neighborhood Hits	593	Target Neighborhood Hits	1069	Shared Neighborhood Hits	98
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SPR1A_MOUSE
θ value	0.00869519 (rank : 81)	NC score	0.130392 (rank : 227)
Query Neighborhood Hits	593	Target Neighborhood Hits	343	Shared Neighborhood Hits	82
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TAU_MOUSE
θ value	0.00869519 (rank : 82)	NC score	0.158765 (rank : 148)
Query Neighborhood Hits	593	Target Neighborhood Hits	502	Shared Neighborhood Hits	133
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CIC_HUMAN
θ value	0.0113563 (rank : 83)	NC score	0.210686 (rank : 83)
Query Neighborhood Hits	593	Target Neighborhood Hits	992	Shared Neighborhood Hits	263
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CSF1_HUMAN
θ value	0.0113563 (rank : 84)	NC score	0.112136 (rank : 292)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	75
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

IRF2_MOUSE
θ value	0.0113563 (rank : 85)	NC score	0.038238 (rank : 896)
Query Neighborhood Hits	593	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

RTP3_MOUSE
θ value	0.0113563 (rank : 86)	NC score	0.146997 (rank : 181)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	116
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SAPS1_HUMAN
θ value	0.0113563 (rank : 87)	NC score	0.136611 (rank : 212)
Query Neighborhood Hits	593	Target Neighborhood Hits	704	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ACK1_HUMAN
θ value	0.0148317 (rank : 88)	NC score	0.044495 (rank : 867)
Query Neighborhood Hits	593	Target Neighborhood Hits	1140	Shared Neighborhood Hits	178
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CRSP2_HUMAN
θ value	0.0148317 (rank : 89)	NC score	0.146827 (rank : 182)
Query Neighborhood Hits	593	Target Neighborhood Hits	380	Shared Neighborhood Hits	105
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

TULP4_HUMAN
θ value	0.0148317 (rank : 90)	NC score	0.089821 (rank : 418)
Query Neighborhood Hits	593	Target Neighborhood Hits	426	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ASPP1_MOUSE
θ value	0.0193708 (rank : 91)	NC score	0.117018 (rank : 269)
Query Neighborhood Hits	593	Target Neighborhood Hits	1244	Shared Neighborhood Hits	196
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BRD4_HUMAN
θ value	0.0193708 (rank : 92)	NC score	0.203813 (rank : 89)
Query Neighborhood Hits	593	Target Neighborhood Hits	851	Shared Neighborhood Hits	250
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CD248_MOUSE
θ value	0.0193708 (rank : 93)	NC score	0.095051 (rank : 386)
Query Neighborhood Hits	593	Target Neighborhood Hits	578	Shared Neighborhood Hits	107
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DHX57_HUMAN
θ value	0.0193708 (rank : 94)	NC score	0.031939 (rank : 930)
Query Neighborhood Hits	593	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

MYO15_MOUSE
θ value	0.0193708 (rank : 95)	NC score	0.070158 (rank : 574)
Query Neighborhood Hits	593	Target Neighborhood Hits	467	Shared Neighborhood Hits	135
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_MOUSE
θ value	0.0193708 (rank : 96)	NC score	0.216517 (rank : 67)
Query Neighborhood Hits	593	Target Neighborhood Hits	1076	Shared Neighborhood Hits	258
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ZN645_HUMAN
θ value	0.0193708 (rank : 97)	NC score	0.121210 (rank : 253)
Query Neighborhood Hits	593	Target Neighborhood Hits	265	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

LAD1_HUMAN
θ value	0.0252991 (rank : 98)	NC score	0.135466 (rank : 216)
Query Neighborhood Hits	593	Target Neighborhood Hits	441	Shared Neighborhood Hits	90
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MISS_MOUSE
θ value	0.0252991 (rank : 99)	NC score	0.194487 (rank : 93)
Query Neighborhood Hits	593	Target Neighborhood Hits	444	Shared Neighborhood Hits	133
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PSL1_HUMAN
θ value	0.0252991 (rank : 100)	NC score	0.115862 (rank : 275)
Query Neighborhood Hits	593	Target Neighborhood Hits	650	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RC3H1_HUMAN
θ value	0.0252991 (rank : 101)	NC score	0.069754 (rank : 579)
Query Neighborhood Hits	593	Target Neighborhood Hits	433	Shared Neighborhood Hits	69
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

ZN516_MOUSE
θ value	0.0252991 (rank : 102)	NC score	0.037342 (rank : 901)
Query Neighborhood Hits	593	Target Neighborhood Hits	1197	Shared Neighborhood Hits	140
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CS016_HUMAN
θ value	0.0330416 (rank : 103)	NC score	0.277689 (rank : 29)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	146
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

KMHN1_HUMAN
θ value	0.0330416 (rank : 104)	NC score	0.024362 (rank : 967)
Query Neighborhood Hits	593	Target Neighborhood Hits	950	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MAST4_HUMAN
θ value	0.0330416 (rank : 105)	NC score	0.044886 (rank : 866)
Query Neighborhood Hits	593	Target Neighborhood Hits	1804	Shared Neighborhood Hits	220
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MINT_MOUSE
θ value	0.0330416 (rank : 106)	NC score	0.157834 (rank : 149)
Query Neighborhood Hits	593	Target Neighborhood Hits	1514	Shared Neighborhood Hits	244
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SELPL_MOUSE
θ value	0.0330416 (rank : 107)	NC score	0.187625 (rank : 106)
Query Neighborhood Hits	593	Target Neighborhood Hits	588	Shared Neighborhood Hits	149
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRRM2_MOUSE
θ value	0.0330416 (rank : 108)	NC score	0.235426 (rank : 54)
Query Neighborhood Hits	593	Target Neighborhood Hits	1470	Shared Neighborhood Hits	289
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AATK_HUMAN
θ value	0.0431538 (rank : 109)	NC score	0.040658 (rank : 881)
Query Neighborhood Hits	593	Target Neighborhood Hits	1243	Shared Neighborhood Hits	146
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CNTRB_MOUSE
θ value	0.0431538 (rank : 110)	NC score	0.050480 (rank : 842)
Query Neighborhood Hits	593	Target Neighborhood Hits	1029	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CUTL1_MOUSE
θ value	0.0431538 (rank : 111)	NC score	0.063069 (rank : 647)
Query Neighborhood Hits	593	Target Neighborhood Hits	1620	Shared Neighborhood Hits	151
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ETV3_HUMAN
θ value	0.0431538 (rank : 112)	NC score	0.069912 (rank : 577)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	76
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

GAK10_HUMAN
θ value	0.0431538 (rank : 113)	NC score	0.136428 (rank : 213)
Query Neighborhood Hits	593	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	0.0431538 (rank : 114)	NC score	0.136421 (rank : 214)
Query Neighborhood Hits	593	Target Neighborhood Hits	268	Shared Neighborhood Hits	71
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK8_HUMAN
θ value	0.0431538 (rank : 115)	NC score	0.124181 (rank : 246)
Query Neighborhood Hits	593	Target Neighborhood Hits	145	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MYH13_HUMAN
θ value	0.0431538 (rank : 116)	NC score	0.023119 (rank : 973)
Query Neighborhood Hits	593	Target Neighborhood Hits	1504	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYO15_HUMAN
θ value	0.0431538 (rank : 117)	NC score	0.086207 (rank : 447)
Query Neighborhood Hits	593	Target Neighborhood Hits	671	Shared Neighborhood Hits	189
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NOTC2_HUMAN
θ value	0.0431538 (rank : 118)	NC score	0.035448 (rank : 910)
Query Neighborhood Hits	593	Target Neighborhood Hits	1113	Shared Neighborhood Hits	114
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PDLI7_HUMAN
θ value	0.0431538 (rank : 119)	NC score	0.056898 (rank : 737)
Query Neighborhood Hits	593	Target Neighborhood Hits	547	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

TP53B_MOUSE
θ value	0.0431538 (rank : 120)	NC score	0.132890 (rank : 221)
Query Neighborhood Hits	593	Target Neighborhood Hits	644	Shared Neighborhood Hits	125
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BCAR1_MOUSE
θ value	0.0563607 (rank : 121)	NC score	0.139300 (rank : 205)
Query Neighborhood Hits	593	Target Neighborhood Hits	438	Shared Neighborhood Hits	131
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PDZD2_HUMAN
θ value	0.0563607 (rank : 122)	NC score	0.096155 (rank : 380)
Query Neighborhood Hits	593	Target Neighborhood Hits	772	Shared Neighborhood Hits	148
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SHAN2_HUMAN
θ value	0.0563607 (rank : 123)	NC score	0.086031 (rank : 448)
Query Neighborhood Hits	593	Target Neighborhood Hits	346	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

ULK1_MOUSE
θ value	0.0563607 (rank : 124)	NC score	0.017501 (rank : 1016)
Query Neighborhood Hits	593	Target Neighborhood Hits	1214	Shared Neighborhood Hits	118
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZIM10_HUMAN
θ value	0.0563607 (rank : 125)	NC score	0.116140 (rank : 271)
Query Neighborhood Hits	593	Target Neighborhood Hits	577	Shared Neighborhood Hits	143
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ANR11_HUMAN
θ value	0.0736092 (rank : 126)	NC score	0.078796 (rank : 489)
Query Neighborhood Hits	593	Target Neighborhood Hits	1289	Shared Neighborhood Hits	168
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CBP_HUMAN
θ value	0.0736092 (rank : 127)	NC score	0.216410 (rank : 68)
Query Neighborhood Hits	593	Target Neighborhood Hits	941	Shared Neighborhood Hits	260
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CNKR2_HUMAN
θ value	0.0736092 (rank : 128)	NC score	0.077814 (rank : 499)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.0736092 (rank : 129)	NC score	0.077869 (rank : 498)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

SPRR3_HUMAN
θ value	0.0736092 (rank : 130)	NC score	0.141453 (rank : 199)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

BCL9_HUMAN
θ value	0.0961366 (rank : 131)	NC score	0.193525 (rank : 95)
Query Neighborhood Hits	593	Target Neighborhood Hits	1008	Shared Neighborhood Hits	222
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CEND1_MOUSE
θ value	0.0961366 (rank : 132)	NC score	0.062952 (rank : 651)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CK024_HUMAN
θ value	0.0961366 (rank : 133)	NC score	0.230729 (rank : 57)
Query Neighborhood Hits	593	Target Neighborhood Hits	408	Shared Neighborhood Hits	133
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CO039_MOUSE
θ value	0.0961366 (rank : 134)	NC score	0.166300 (rank : 140)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	158
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

FOXN1_MOUSE
θ value	0.0961366 (rank : 135)	NC score	0.047860 (rank : 855)
Query Neighborhood Hits	593	Target Neighborhood Hits	300	Shared Neighborhood Hits	58
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

IL3RB_MOUSE
θ value	0.0961366 (rank : 136)	NC score	0.085071 (rank : 452)
Query Neighborhood Hits	593	Target Neighborhood Hits	355	Shared Neighborhood Hits	78
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

K1543_MOUSE
θ value	0.0961366 (rank : 137)	NC score	0.152573 (rank : 163)
Query Neighborhood Hits	593	Target Neighborhood Hits	497	Shared Neighborhood Hits	130
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MYH14_MOUSE
θ value	0.0961366 (rank : 138)	NC score	0.024972 (rank : 962)
Query Neighborhood Hits	593	Target Neighborhood Hits	1225	Shared Neighborhood Hits	61
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PCD12_MOUSE
θ value	0.0961366 (rank : 139)	NC score	0.007512 (rank : 1077)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	15
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

RP3A_MOUSE
θ value	0.0961366 (rank : 140)	NC score	0.069991 (rank : 575)
Query Neighborhood Hits	593	Target Neighborhood Hits	510	Shared Neighborhood Hits	109
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SC24A_MOUSE
θ value	0.0961366 (rank : 141)	NC score	0.142986 (rank : 195)
Query Neighborhood Hits	593	Target Neighborhood Hits	394	Shared Neighborhood Hits	129
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SOX13_MOUSE
θ value	0.0961366 (rank : 142)	NC score	0.072116 (rank : 551)
Query Neighborhood Hits	593	Target Neighborhood Hits	495	Shared Neighborhood Hits	106
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRBP1_MOUSE
θ value	0.0961366 (rank : 143)	NC score	0.110277 (rank : 296)
Query Neighborhood Hits	593	Target Neighborhood Hits	384	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

STAT2_MOUSE
θ value	0.0961366 (rank : 144)	NC score	0.041596 (rank : 877)
Query Neighborhood Hits	593	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SYNJ1_MOUSE
θ value	0.0961366 (rank : 145)	NC score	0.176665 (rank : 120)
Query Neighborhood Hits	593	Target Neighborhood Hits	516	Shared Neighborhood Hits	220
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZN687_HUMAN
θ value	0.0961366 (rank : 146)	NC score	0.059335 (rank : 694)
Query Neighborhood Hits	593	Target Neighborhood Hits	1244	Shared Neighborhood Hits	163
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CBL_MOUSE
θ value	0.125558 (rank : 147)	NC score	0.071947 (rank : 556)
Query Neighborhood Hits	593	Target Neighborhood Hits	426	Shared Neighborhood Hits	75
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

GAK7_HUMAN
θ value	0.125558 (rank : 148)	NC score	0.124563 (rank : 243)
Query Neighborhood Hits	593	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

MILK1_MOUSE
θ value	0.125558 (rank : 149)	NC score	0.174316 (rank : 126)
Query Neighborhood Hits	593	Target Neighborhood Hits	788	Shared Neighborhood Hits	214
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PO6F1_MOUSE
θ value	0.125558 (rank : 150)	NC score	0.043813 (rank : 869)
Query Neighborhood Hits	593	Target Neighborhood Hits	581	Shared Neighborhood Hits	83
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

SOX13_HUMAN
θ value	0.125558 (rank : 151)	NC score	0.077163 (rank : 504)
Query Neighborhood Hits	593	Target Neighborhood Hits	464	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

UBP36_HUMAN
θ value	0.125558 (rank : 152)	NC score	0.057767 (rank : 727)
Query Neighborhood Hits	593	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

BAT2_HUMAN
θ value	0.163984 (rank : 153)	NC score	0.259841 (rank : 33)
Query Neighborhood Hits	593	Target Neighborhood Hits	931	Shared Neighborhood Hits	275
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
θ value	0.163984 (rank : 154)	NC score	0.231777 (rank : 56)
Query Neighborhood Hits	593	Target Neighborhood Hits	1537	Shared Neighborhood Hits	303
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DHX57_MOUSE
θ value	0.163984 (rank : 155)	NC score	0.028694 (rank : 946)
Query Neighborhood Hits	593	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

EVI1_HUMAN
θ value	0.163984 (rank : 156)	NC score	0.012397 (rank : 1051)
Query Neighborhood Hits	593	Target Neighborhood Hits	924	Shared Neighborhood Hits	61
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

INVO_HUMAN
θ value	0.163984 (rank : 157)	NC score	0.052918 (rank : 802)
Query Neighborhood Hits	593	Target Neighborhood Hits	636	Shared Neighborhood Hits	71
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

PRGC2_MOUSE
θ value	0.163984 (rank : 158)	NC score	0.080540 (rank : 477)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RPGF1_HUMAN
θ value	0.163984 (rank : 159)	NC score	0.055864 (rank : 752)
Query Neighborhood Hits	593	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SF3B1_HUMAN
θ value	0.163984 (rank : 160)	NC score	0.107995 (rank : 309)
Query Neighborhood Hits	593	Target Neighborhood Hits	341	Shared Neighborhood Hits	76
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.163984 (rank : 161)	NC score	0.107843 (rank : 311)
Query Neighborhood Hits	593	Target Neighborhood Hits	352	Shared Neighborhood Hits	77
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ZCPW1_MOUSE
θ value	0.163984 (rank : 162)	NC score	0.070262 (rank : 573)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ACK1_MOUSE
θ value	0.21417 (rank : 163)	NC score	0.039571 (rank : 885)
Query Neighborhood Hits	593	Target Neighborhood Hits	1080	Shared Neighborhood Hits	157
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ADA12_MOUSE
θ value	0.21417 (rank : 164)	NC score	0.030770 (rank : 934)
Query Neighborhood Hits	593	Target Neighborhood Hits	474	Shared Neighborhood Hits	93
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BRD4_MOUSE
θ value	0.21417 (rank : 165)	NC score	0.216129 (rank : 70)
Query Neighborhood Hits	593	Target Neighborhood Hits	845	Shared Neighborhood Hits	241
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CSPG3_HUMAN
θ value	0.21417 (rank : 166)	NC score	0.039533 (rank : 886)
Query Neighborhood Hits	593	Target Neighborhood Hits	676	Shared Neighborhood Hits	89
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DLG5_HUMAN
θ value	0.21417 (rank : 167)	NC score	0.042472 (rank : 874)
Query Neighborhood Hits	593	Target Neighborhood Hits	1088	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DOCK4_HUMAN
θ value	0.21417 (rank : 168)	NC score	0.054696 (rank : 769)
Query Neighborhood Hits	593	Target Neighborhood Hits	237	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

FAT2_HUMAN
θ value	0.21417 (rank : 169)	NC score	0.012023 (rank : 1053)
Query Neighborhood Hits	593	Target Neighborhood Hits	507	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

IQEC2_MOUSE
θ value	0.21417 (rank : 170)	NC score	0.095254 (rank : 384)
Query Neighborhood Hits	593	Target Neighborhood Hits	417	Shared Neighborhood Hits	137
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SRRM1_HUMAN
θ value	0.21417 (rank : 171)	NC score	0.320544 (rank : 17)
Query Neighborhood Hits	593	Target Neighborhood Hits	690	Shared Neighborhood Hits	220
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

STAR8_HUMAN
θ value	0.21417 (rank : 172)	NC score	0.040736 (rank : 879)
Query Neighborhood Hits	593	Target Neighborhood Hits	216	Shared Neighborhood Hits	43
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

ZIMP7_MOUSE
θ value	0.21417 (rank : 173)	NC score	0.109261 (rank : 303)
Query Neighborhood Hits	593	Target Neighborhood Hits	566	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CI079_HUMAN
θ value	0.279714 (rank : 174)	NC score	0.120795 (rank : 257)
Query Neighborhood Hits	593	Target Neighborhood Hits	288	Shared Neighborhood Hits	91
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

FBLI1_HUMAN
θ value	0.279714 (rank : 175)	NC score	0.056602 (rank : 739)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

FRAS1_HUMAN
θ value	0.279714 (rank : 176)	NC score	0.018235 (rank : 1010)
Query Neighborhood Hits	593	Target Neighborhood Hits	759	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KCNQ2_MOUSE
θ value	0.279714 (rank : 177)	NC score	0.017117 (rank : 1019)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KIF1B_MOUSE
θ value	0.279714 (rank : 178)	NC score	0.017354 (rank : 1017)
Query Neighborhood Hits	593	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

NPAS4_MOUSE
θ value	0.279714 (rank : 179)	NC score	0.097194 (rank : 374)
Query Neighborhood Hits	593	Target Neighborhood Hits	245	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

POLS_MOUSE
θ value	0.279714 (rank : 180)	NC score	0.039088 (rank : 891)
Query Neighborhood Hits	593	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

SOX30_HUMAN
θ value	0.279714 (rank : 181)	NC score	0.070521 (rank : 570)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	80
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

STAT6_HUMAN
θ value	0.279714 (rank : 182)	NC score	0.034643 (rank : 917)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	31
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

SYGP1_HUMAN
θ value	0.279714 (rank : 183)	NC score	0.031233 (rank : 931)
Query Neighborhood Hits	593	Target Neighborhood Hits	589	Shared Neighborhood Hits	43
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

WIRE_HUMAN
θ value	0.279714 (rank : 184)	NC score	0.305482 (rank : 21)
Query Neighborhood Hits	593	Target Neighborhood Hits	329	Shared Neighborhood Hits	192
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ZN687_MOUSE
θ value	0.279714 (rank : 185)	NC score	0.038781 (rank : 892)
Query Neighborhood Hits	593	Target Neighborhood Hits	913	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

APC_HUMAN
θ value	0.365318 (rank : 186)	NC score	0.095031 (rank : 387)
Query Neighborhood Hits	593	Target Neighborhood Hits	603	Shared Neighborhood Hits	105
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BIN1_HUMAN
θ value	0.365318 (rank : 187)	NC score	0.078936 (rank : 488)
Query Neighborhood Hits	593	Target Neighborhood Hits	335	Shared Neighborhood Hits	75
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BLNK_MOUSE
θ value	0.365318 (rank : 188)	NC score	0.112308 (rank : 291)
Query Neighborhood Hits	593	Target Neighborhood Hits	296	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CASC3_MOUSE
θ value	0.365318 (rank : 189)	NC score	0.113709 (rank : 284)
Query Neighborhood Hits	593	Target Neighborhood Hits	333	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

EGR1_MOUSE
θ value	0.365318 (rank : 190)	NC score	0.020504 (rank : 998)
Query Neighborhood Hits	593	Target Neighborhood Hits	816	Shared Neighborhood Hits	81
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

IL4RA_MOUSE
θ value	0.365318 (rank : 191)	NC score	0.065490 (rank : 626)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	50
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

LARP4_MOUSE
θ value	0.365318 (rank : 192)	NC score	0.089706 (rank : 420)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MKL1_MOUSE
θ value	0.365318 (rank : 193)	NC score	0.098906 (rank : 361)
Query Neighborhood Hits	593	Target Neighborhood Hits	667	Shared Neighborhood Hits	148
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MMAC_HUMAN
θ value	0.365318 (rank : 194)	NC score	0.046242 (rank : 859)
Query Neighborhood Hits	593	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

MNT_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.189795 (rank : 99)
Query Neighborhood Hits	593	Target Neighborhood Hits	496	Shared Neighborhood Hits	161
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NDF1_MOUSE
θ value	0.365318 (rank : 196)	NC score	0.029507 (rank : 941)
Query Neighborhood Hits	593	Target Neighborhood Hits	209	Shared Neighborhood Hits	34
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NPAS4_HUMAN
θ value	0.365318 (rank : 197)	NC score	0.075353 (rank : 514)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PHC1_MOUSE
θ value	0.365318 (rank : 198)	NC score	0.109653 (rank : 300)
Query Neighborhood Hits	593	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

PKN3_MOUSE
θ value	0.365318 (rank : 199)	NC score	0.006063 (rank : 1084)
Query Neighborhood Hits	593	Target Neighborhood Hits	1009	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PRGC2_HUMAN
θ value	0.365318 (rank : 200)	NC score	0.084017 (rank : 456)
Query Neighborhood Hits	593	Target Neighborhood Hits	272	Shared Neighborhood Hits	62
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RN165_HUMAN
θ value	0.365318 (rank : 201)	NC score	0.030556 (rank : 935)
Query Neighborhood Hits	593	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RTN4_MOUSE
θ value	0.365318 (rank : 202)	NC score	0.114933 (rank : 278)
Query Neighborhood Hits	593	Target Neighborhood Hits	341	Shared Neighborhood Hits	101
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SPEG_MOUSE
θ value	0.365318 (rank : 203)	NC score	0.056104 (rank : 749)
Query Neighborhood Hits	593	Target Neighborhood Hits	1959	Shared Neighborhood Hits	266
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPT5H_HUMAN
θ value	0.365318 (rank : 204)	NC score	0.119247 (rank : 261)
Query Neighborhood Hits	593	Target Neighborhood Hits	436	Shared Neighborhood Hits	121
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.365318 (rank : 205)	NC score	0.120906 (rank : 256)
Query Neighborhood Hits	593	Target Neighborhood Hits	437	Shared Neighborhood Hits	122
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TRAK2_HUMAN
θ value	0.365318 (rank : 206)	NC score	0.039610 (rank : 884)
Query Neighborhood Hits	593	Target Neighborhood Hits	476	Shared Neighborhood Hits	32
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

BCL3_MOUSE
θ value	0.47712 (rank : 207)	NC score	0.028696 (rank : 945)
Query Neighborhood Hits	593	Target Neighborhood Hits	388	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

DDX20_MOUSE
θ value	0.47712 (rank : 208)	NC score	0.011003 (rank : 1055)
Query Neighborhood Hits	593	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

EGR3_HUMAN
θ value	0.47712 (rank : 209)	NC score	0.012434 (rank : 1050)
Query Neighborhood Hits	593	Target Neighborhood Hits	746	Shared Neighborhood Hits	44
SwissProt Accessions	Q06889	Gene names	EGR3, PILOT
Domain Architecture	No domain graphic available
Description	Early growth response protein 3 (EGR-3) (Zinc finger protein pilot).

EGR3_MOUSE
θ value	0.47712 (rank : 210)	NC score	0.012454 (rank : 1049)
Query Neighborhood Hits	593	Target Neighborhood Hits	747	Shared Neighborhood Hits	44
SwissProt Accessions	P43300, Q9R276	Gene names	Egr3, Egr-3
Domain Architecture
Description	Early growth response protein 3 (EGR-3).

MLL2_HUMAN
θ value	0.47712 (rank : 211)	NC score	0.247856 (rank : 43)
Query Neighborhood Hits	593	Target Neighborhood Hits	1788	Shared Neighborhood Hits	361
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NPBL_MOUSE
θ value	0.47712 (rank : 212)	NC score	0.094056 (rank : 396)
Query Neighborhood Hits	593	Target Neighborhood Hits	1041	Shared Neighborhood Hits	133
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PHLB1_HUMAN
θ value	0.47712 (rank : 213)	NC score	0.097890 (rank : 370)
Query Neighborhood Hits	593	Target Neighborhood Hits	1038	Shared Neighborhood Hits	166
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRD16_HUMAN
θ value	0.47712 (rank : 214)	NC score	0.012601 (rank : 1048)
Query Neighborhood Hits	593	Target Neighborhood Hits	832	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

SI1L3_HUMAN
θ value	0.47712 (rank : 215)	NC score	0.047321 (rank : 857)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	75
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SYNP2_HUMAN
θ value	0.47712 (rank : 216)	NC score	0.081239 (rank : 473)
Query Neighborhood Hits	593	Target Neighborhood Hits	323	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ATX7_MOUSE
θ value	0.62314 (rank : 217)	NC score	0.097234 (rank : 373)
Query Neighborhood Hits	593	Target Neighborhood Hits	328	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAT3_HUMAN
θ value	0.62314 (rank : 218)	NC score	0.153777 (rank : 159)
Query Neighborhood Hits	593	Target Neighborhood Hits	490	Shared Neighborhood Hits	127
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	0.62314 (rank : 219)	NC score	0.181518 (rank : 113)
Query Neighborhood Hits	593	Target Neighborhood Hits	518	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CABIN_HUMAN
θ value	0.62314 (rank : 220)	NC score	0.150542 (rank : 170)
Query Neighborhood Hits	593	Target Neighborhood Hits	490	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CECR2_HUMAN
θ value	0.62314 (rank : 221)	NC score	0.094765 (rank : 389)
Query Neighborhood Hits	593	Target Neighborhood Hits	543	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

GGA2_MOUSE
θ value	0.62314 (rank : 222)	NC score	0.024654 (rank : 965)
Query Neighborhood Hits	593	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GRIP2_HUMAN
θ value	0.62314 (rank : 223)	NC score	0.030862 (rank : 933)
Query Neighborhood Hits	593	Target Neighborhood Hits	256	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

KLF17_HUMAN
θ value	0.62314 (rank : 224)	NC score	0.021603 (rank : 986)
Query Neighborhood Hits	593	Target Neighborhood Hits	882	Shared Neighborhood Hits	96
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

MEF2B_HUMAN
θ value	0.62314 (rank : 225)	NC score	0.072453 (rank : 545)
Query Neighborhood Hits	593	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MEGF9_MOUSE
θ value	0.62314 (rank : 226)	NC score	0.082685 (rank : 465)
Query Neighborhood Hits	593	Target Neighborhood Hits	896	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SOS1_HUMAN
θ value	0.62314 (rank : 227)	NC score	0.067457 (rank : 605)
Query Neighborhood Hits	593	Target Neighborhood Hits	274	Shared Neighborhood Hits	90
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

WIRE_MOUSE
θ value	0.62314 (rank : 228)	NC score	0.284569 (rank : 25)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	178
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

AP180_MOUSE
θ value	0.813845 (rank : 229)	NC score	0.132820 (rank : 222)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	71
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

CCD21_MOUSE
θ value	0.813845 (rank : 230)	NC score	0.030400 (rank : 937)
Query Neighborhood Hits	593	Target Neighborhood Hits	1135	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CD2_HUMAN
θ value	0.813845 (rank : 231)	NC score	0.107005 (rank : 318)
Query Neighborhood Hits	593	Target Neighborhood Hits	504	Shared Neighborhood Hits	110
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CG1_HUMAN
θ value	0.813845 (rank : 232)	NC score	0.126472 (rank : 236)
Query Neighborhood Hits	593	Target Neighborhood Hits	222	Shared Neighborhood Hits	82
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CS007_MOUSE
θ value	0.813845 (rank : 233)	NC score	0.156212 (rank : 152)
Query Neighborhood Hits	593	Target Neighborhood Hits	464	Shared Neighborhood Hits	147
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DOK2_MOUSE
θ value	0.813845 (rank : 234)	NC score	0.045092 (rank : 865)
Query Neighborhood Hits	593	Target Neighborhood Hits	244	Shared Neighborhood Hits	55
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

E2F4_HUMAN
θ value	0.813845 (rank : 235)	NC score	0.051560 (rank : 821)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	50
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

ELK4_HUMAN
θ value	0.813845 (rank : 236)	NC score	0.045467 (rank : 863)
Query Neighborhood Hits	593	Target Neighborhood Hits	184	Shared Neighborhood Hits	49
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ERRFI_HUMAN
θ value	0.813845 (rank : 237)	NC score	0.085612 (rank : 451)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

GAK3_HUMAN
θ value	0.813845 (rank : 238)	NC score	0.122864 (rank : 247)
Query Neighborhood Hits	593	Target Neighborhood Hits	182	Shared Neighborhood Hits	42
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GLI1_HUMAN
θ value	0.813845 (rank : 239)	NC score	0.014030 (rank : 1037)
Query Neighborhood Hits	593	Target Neighborhood Hits	828	Shared Neighborhood Hits	65
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HN1L_HUMAN
θ value	0.813845 (rank : 240)	NC score	0.059426 (rank : 693)
Query Neighborhood Hits	593	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

HXB3_HUMAN
θ value	0.813845 (rank : 241)	NC score	0.014014 (rank : 1038)
Query Neighborhood Hits	593	Target Neighborhood Hits	559	Shared Neighborhood Hits	68
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

ITSN1_HUMAN
θ value	0.813845 (rank : 242)	NC score	0.037844 (rank : 898)
Query Neighborhood Hits	593	Target Neighborhood Hits	1757	Shared Neighborhood Hits	145
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

JIP1_MOUSE
θ value	0.813845 (rank : 243)	NC score	0.073499 (rank : 535)
Query Neighborhood Hits	593	Target Neighborhood Hits	259	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP3_HUMAN
θ value	0.813845 (rank : 244)	NC score	0.049320 (rank : 848)
Query Neighborhood Hits	593	Target Neighborhood Hits	1039	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MAP1A_HUMAN
θ value	0.813845 (rank : 245)	NC score	0.118217 (rank : 265)
Query Neighborhood Hits	593	Target Neighborhood Hits	1626	Shared Neighborhood Hits	223
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYLK_MOUSE
θ value	0.813845 (rank : 246)	NC score	0.015260 (rank : 1032)
Query Neighborhood Hits	593	Target Neighborhood Hits	1489	Shared Neighborhood Hits	99
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NFRKB_HUMAN
θ value	0.813845 (rank : 247)	NC score	0.129697 (rank : 229)
Query Neighborhood Hits	593	Target Neighborhood Hits	211	Shared Neighborhood Hits	65
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PTN22_MOUSE
θ value	0.813845 (rank : 248)	NC score	0.019277 (rank : 1001)
Query Neighborhood Hits	593	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

RABE1_HUMAN
θ value	0.813845 (rank : 249)	NC score	0.022471 (rank : 979)
Query Neighborhood Hits	593	Target Neighborhood Hits	1104	Shared Neighborhood Hits	59
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SAPS1_MOUSE
θ value	0.813845 (rank : 250)	NC score	0.067788 (rank : 600)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SFPQ_HUMAN
θ value	0.813845 (rank : 251)	NC score	0.209561 (rank : 84)
Query Neighborhood Hits	593	Target Neighborhood Hits	986	Shared Neighborhood Hits	253
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFRIP_HUMAN
θ value	0.813845 (rank : 252)	NC score	0.092605 (rank : 405)
Query Neighborhood Hits	593	Target Neighborhood Hits	530	Shared Neighborhood Hits	86
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

YETS2_HUMAN
θ value	0.813845 (rank : 253)	NC score	0.070967 (rank : 564)
Query Neighborhood Hits	593	Target Neighborhood Hits	212	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZN409_HUMAN
θ value	0.813845 (rank : 254)	NC score	0.048997 (rank : 850)
Query Neighborhood Hits	593	Target Neighborhood Hits	842	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

AFF2_MOUSE
θ value	1.06291 (rank : 255)	NC score	0.080877 (rank : 475)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

ATS14_HUMAN
θ value	1.06291 (rank : 256)	NC score	0.021627 (rank : 985)
Query Neighborhood Hits	593	Target Neighborhood Hits	382	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

CN092_MOUSE
θ value	1.06291 (rank : 257)	NC score	0.069565 (rank : 580)
Query Neighborhood Hits	593	Target Neighborhood Hits	206	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

FBLI1_MOUSE
θ value	1.06291 (rank : 258)	NC score	0.065691 (rank : 624)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	69
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

GAB2_HUMAN
θ value	1.06291 (rank : 259)	NC score	0.079454 (rank : 484)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GATA6_MOUSE
θ value	1.06291 (rank : 260)	NC score	0.016775 (rank : 1021)
Query Neighborhood Hits	593	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	Q61169, P97729, Q9QZK3	Gene names	Gata6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

GPS2_HUMAN
θ value	1.06291 (rank : 261)	NC score	0.065687 (rank : 625)
Query Neighborhood Hits	593	Target Neighborhood Hits	459	Shared Neighborhood Hits	67
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

HCLS1_HUMAN
θ value	1.06291 (rank : 262)	NC score	0.066371 (rank : 618)
Query Neighborhood Hits	593	Target Neighborhood Hits	358	Shared Neighborhood Hits	87
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCN1_HUMAN
θ value	1.06291 (rank : 263)	NC score	0.018458 (rank : 1007)
Query Neighborhood Hits	593	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

IL3B2_MOUSE
θ value	1.06291 (rank : 264)	NC score	0.082812 (rank : 464)
Query Neighborhood Hits	593	Target Neighborhood Hits	372	Shared Neighborhood Hits	83
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

PHLB1_MOUSE
θ value	1.06291 (rank : 265)	NC score	0.088436 (rank : 432)
Query Neighborhood Hits	593	Target Neighborhood Hits	678	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PI5PA_HUMAN
θ value	1.06291 (rank : 266)	NC score	0.169086 (rank : 131)
Query Neighborhood Hits	593	Target Neighborhood Hits	749	Shared Neighborhood Hits	224
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RHG25_MOUSE
θ value	1.06291 (rank : 267)	NC score	0.043139 (rank : 871)
Query Neighborhood Hits	593	Target Neighborhood Hits	492	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SNPC4_HUMAN
θ value	1.06291 (rank : 268)	NC score	0.124949 (rank : 242)
Query Neighborhood Hits	593	Target Neighborhood Hits	589	Shared Neighborhood Hits	137
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TAB3_MOUSE
θ value	1.06291 (rank : 269)	NC score	0.100026 (rank : 350)
Query Neighborhood Hits	593	Target Neighborhood Hits	273	Shared Neighborhood Hits	97
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

THAP7_MOUSE
θ value	1.06291 (rank : 270)	NC score	0.034521 (rank : 918)
Query Neighborhood Hits	593	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

ZN142_HUMAN
θ value	1.06291 (rank : 271)	NC score	0.013772 (rank : 1041)
Query Neighborhood Hits	593	Target Neighborhood Hits	1007	Shared Neighborhood Hits	104
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

AFF2_HUMAN
θ value	1.38821 (rank : 272)	NC score	0.074426 (rank : 520)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	56
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

ATN1_HUMAN
θ value	1.38821 (rank : 273)	NC score	0.259229 (rank : 35)
Query Neighborhood Hits	593	Target Neighborhood Hits	676	Shared Neighborhood Hits	225
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX1_MOUSE
θ value	1.38821 (rank : 274)	NC score	0.068156 (rank : 595)
Query Neighborhood Hits	593	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ATX2_MOUSE
θ value	1.38821 (rank : 275)	NC score	0.143033 (rank : 193)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	150
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

ATX7_HUMAN
θ value	1.38821 (rank : 276)	NC score	0.098827 (rank : 362)
Query Neighborhood Hits	593	Target Neighborhood Hits	351	Shared Neighborhood Hits	94
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BCL9_MOUSE
θ value	1.38821 (rank : 277)	NC score	0.185200 (rank : 108)
Query Neighborhood Hits	593	Target Neighborhood Hits	770	Shared Neighborhood Hits	201
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CHD5_HUMAN
θ value	1.38821 (rank : 278)	NC score	0.022138 (rank : 980)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CIC_MOUSE
θ value	1.38821 (rank : 279)	NC score	0.188409 (rank : 103)
Query Neighborhood Hits	593	Target Neighborhood Hits	742	Shared Neighborhood Hits	222
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CRTC1_HUMAN
θ value	1.38821 (rank : 280)	NC score	0.166670 (rank : 139)
Query Neighborhood Hits	593	Target Neighborhood Hits	319	Shared Neighborhood Hits	135
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CSKI1_HUMAN
θ value	1.38821 (rank : 281)	NC score	0.129545 (rank : 230)
Query Neighborhood Hits	593	Target Neighborhood Hits	997	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	1.38821 (rank : 282)	NC score	0.121148 (rank : 254)
Query Neighborhood Hits	593	Target Neighborhood Hits	1031	Shared Neighborhood Hits	257
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTGE6_HUMAN
θ value	1.38821 (rank : 283)	NC score	0.024678 (rank : 964)
Query Neighborhood Hits	593	Target Neighborhood Hits	650	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

EFS_MOUSE
θ value	1.38821 (rank : 284)	NC score	0.126412 (rank : 237)
Query Neighborhood Hits	593	Target Neighborhood Hits	389	Shared Neighborhood Hits	98
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

FOXH1_HUMAN
θ value	1.38821 (rank : 285)	NC score	0.024415 (rank : 966)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

G137B_HUMAN
θ value	1.38821 (rank : 286)	NC score	0.036668 (rank : 905)
Query Neighborhood Hits	593	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

GLI2_HUMAN
θ value	1.38821 (rank : 287)	NC score	0.017097 (rank : 1020)
Query Neighborhood Hits	593	Target Neighborhood Hits	971	Shared Neighborhood Hits	103
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

IF4B_HUMAN
θ value	1.38821 (rank : 288)	NC score	0.054067 (rank : 780)
Query Neighborhood Hits	593	Target Neighborhood Hits	417	Shared Neighborhood Hits	71
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IGHD_HUMAN
θ value	1.38821 (rank : 289)	NC score	0.015987 (rank : 1026)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	P01880	Gene names	IGHD
Domain Architecture	No domain graphic available
Description	Ig delta chain C region.

K1543_HUMAN
θ value	1.38821 (rank : 290)	NC score	0.146258 (rank : 185)
Query Neighborhood Hits	593	Target Neighborhood Hits	435	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAGD4_HUMAN
θ value	1.38821 (rank : 291)	NC score	0.059139 (rank : 699)
Query Neighborhood Hits	593	Target Neighborhood Hits	338	Shared Neighborhood Hits	85
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MAP1B_MOUSE
θ value	1.38821 (rank : 292)	NC score	0.087137 (rank : 444)
Query Neighborhood Hits	593	Target Neighborhood Hits	977	Shared Neighborhood Hits	135
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MUCDL_HUMAN
θ value	1.38821 (rank : 293)	NC score	0.157353 (rank : 150)
Query Neighborhood Hits	593	Target Neighborhood Hits	777	Shared Neighborhood Hits	175
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCEN_MOUSE
θ value	1.38821 (rank : 294)	NC score	0.053744 (rank : 786)
Query Neighborhood Hits	593	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

NIPA_HUMAN
θ value	1.38821 (rank : 295)	NC score	0.040697 (rank : 880)
Query Neighborhood Hits	593	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

NIPBL_HUMAN
θ value	1.38821 (rank : 296)	NC score	0.093888 (rank : 397)
Query Neighborhood Hits	593	Target Neighborhood Hits	1311	Shared Neighborhood Hits	152
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

P3H1_HUMAN
θ value	1.38821 (rank : 297)	NC score	0.013026 (rank : 1045)
Query Neighborhood Hits	593	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

PHC3_HUMAN
θ value	1.38821 (rank : 298)	NC score	0.099821 (rank : 352)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PHF3_HUMAN
θ value	1.38821 (rank : 299)	NC score	0.046189 (rank : 860)
Query Neighborhood Hits	593	Target Neighborhood Hits	419	Shared Neighborhood Hits	49
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RASA1_HUMAN
θ value	1.38821 (rank : 300)	NC score	0.072548 (rank : 544)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SPRR3_MOUSE
θ value	1.38821 (rank : 301)	NC score	0.137370 (rank : 210)
Query Neighborhood Hits	593	Target Neighborhood Hits	106	Shared Neighborhood Hits	38
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TM55B_MOUSE
θ value	1.38821 (rank : 302)	NC score	0.026856 (rank : 956)
Query Neighborhood Hits	593	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

UBP42_HUMAN
θ value	1.38821 (rank : 303)	NC score	0.058264 (rank : 718)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

WASIP_MOUSE
θ value	1.38821 (rank : 304)	NC score	0.346627 (rank : 14)
Query Neighborhood Hits	593	Target Neighborhood Hits	392	Shared Neighborhood Hits	216
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ZCH11_HUMAN
θ value	1.38821 (rank : 305)	NC score	0.053829 (rank : 785)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	62
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ZN605_HUMAN
θ value	1.38821 (rank : 306)	NC score	0.001838 (rank : 1099)
Query Neighborhood Hits	593	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q86T29, Q86T91	Gene names	ZNF605
Domain Architecture	No domain graphic available
Description	Zinc finger protein 605.

ABCA7_HUMAN
θ value	1.81305 (rank : 307)	NC score	0.006176 (rank : 1083)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

AFF1_HUMAN
θ value	1.81305 (rank : 308)	NC score	0.143138 (rank : 192)
Query Neighborhood Hits	593	Target Neighborhood Hits	506	Shared Neighborhood Hits	128
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ARI1A_HUMAN
θ value	1.81305 (rank : 309)	NC score	0.168662 (rank : 132)
Query Neighborhood Hits	593	Target Neighborhood Hits	787	Shared Neighborhood Hits	206
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CBL_HUMAN
θ value	1.81305 (rank : 310)	NC score	0.058179 (rank : 722)
Query Neighborhood Hits	593	Target Neighborhood Hits	353	Shared Neighborhood Hits	59
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CENPC_HUMAN
θ value	1.81305 (rank : 311)	NC score	0.028852 (rank : 944)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

DOCK4_MOUSE
θ value	1.81305 (rank : 312)	NC score	0.052649 (rank : 806)
Query Neighborhood Hits	593	Target Neighborhood Hits	210	Shared Neighborhood Hits	65
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

FRAS1_MOUSE
θ value	1.81305 (rank : 313)	NC score	0.018452 (rank : 1008)
Query Neighborhood Hits	593	Target Neighborhood Hits	747	Shared Neighborhood Hits	23
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GAB2_MOUSE
θ value	1.81305 (rank : 314)	NC score	0.080721 (rank : 476)
Query Neighborhood Hits	593	Target Neighborhood Hits	220	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GGA2_HUMAN
θ value	1.81305 (rank : 315)	NC score	0.026363 (rank : 958)
Query Neighborhood Hits	593	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

HLF_HUMAN
θ value	1.81305 (rank : 316)	NC score	0.032961 (rank : 925)
Query Neighborhood Hits	593	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

HLF_MOUSE
θ value	1.81305 (rank : 317)	NC score	0.032209 (rank : 929)
Query Neighborhood Hits	593	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

ITSN1_MOUSE
θ value	1.81305 (rank : 318)	NC score	0.039318 (rank : 889)
Query Neighborhood Hits	593	Target Neighborhood Hits	1669	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

JIP1_HUMAN
θ value	1.81305 (rank : 319)	NC score	0.069258 (rank : 586)
Query Neighborhood Hits	593	Target Neighborhood Hits	271	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KI67_HUMAN
θ value	1.81305 (rank : 320)	NC score	0.118296 (rank : 264)
Query Neighborhood Hits	593	Target Neighborhood Hits	581	Shared Neighborhood Hits	94
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIF1B_HUMAN
θ value	1.81305 (rank : 321)	NC score	0.015669 (rank : 1028)
Query Neighborhood Hits	593	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

MA1B1_HUMAN
θ value	1.81305 (rank : 322)	NC score	0.030428 (rank : 936)
Query Neighborhood Hits	593	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MAN1_HUMAN
θ value	1.81305 (rank : 323)	NC score	0.026901 (rank : 955)
Query Neighborhood Hits	593	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2U8, Q9NT47, Q9NYA5	Gene names	LEMD3, MAN1
Domain Architecture
Description	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3).

MARK2_HUMAN
θ value	1.81305 (rank : 324)	NC score	0.008090 (rank : 1073)
Query Neighborhood Hits	593	Target Neighborhood Hits	1056	Shared Neighborhood Hits	75
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MNT_MOUSE
θ value	1.81305 (rank : 325)	NC score	0.175856 (rank : 123)
Query Neighborhood Hits	593	Target Neighborhood Hits	432	Shared Neighborhood Hits	145
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NEB2_MOUSE
θ value	1.81305 (rank : 326)	NC score	0.041153 (rank : 878)
Query Neighborhood Hits	593	Target Neighborhood Hits	889	Shared Neighborhood Hits	71
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFAC1_HUMAN
θ value	1.81305 (rank : 327)	NC score	0.071246 (rank : 562)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	112
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NID2_HUMAN
θ value	1.81305 (rank : 328)	NC score	0.016363 (rank : 1023)
Query Neighborhood Hits	593	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NU155_HUMAN
θ value	1.81305 (rank : 329)	NC score	0.022583 (rank : 978)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	O75694, Q9UBE9, Q9UFL5	Gene names	NUP155, KIAA0791
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

PHC1_HUMAN
θ value	1.81305 (rank : 330)	NC score	0.114178 (rank : 280)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PRAX_HUMAN
θ value	1.81305 (rank : 331)	NC score	0.104619 (rank : 326)
Query Neighborhood Hits	593	Target Neighborhood Hits	215	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRG4_MOUSE
θ value	1.81305 (rank : 332)	NC score	0.280217 (rank : 28)
Query Neighborhood Hits	593	Target Neighborhood Hits	624	Shared Neighborhood Hits	207
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

T22D4_HUMAN
θ value	1.81305 (rank : 333)	NC score	0.075983 (rank : 511)
Query Neighborhood Hits	593	Target Neighborhood Hits	403	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

WASF2_HUMAN
θ value	1.81305 (rank : 334)	NC score	0.212633 (rank : 78)
Query Neighborhood Hits	593	Target Neighborhood Hits	280	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF4_HUMAN
θ value	1.81305 (rank : 335)	NC score	0.215337 (rank : 73)
Query Neighborhood Hits	593	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ZN688_HUMAN
θ value	1.81305 (rank : 336)	NC score	0.007235 (rank : 1078)
Query Neighborhood Hits	593	Target Neighborhood Hits	873	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ZN750_MOUSE
θ value	1.81305 (rank : 337)	NC score	0.101766 (rank : 340)
Query Neighborhood Hits	593	Target Neighborhood Hits	346	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AAK1_HUMAN
θ value	2.36792 (rank : 338)	NC score	0.048122 (rank : 854)
Query Neighborhood Hits	593	Target Neighborhood Hits	1077	Shared Neighborhood Hits	142
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AMBN_HUMAN
θ value	2.36792 (rank : 339)	NC score	0.032978 (rank : 924)
Query Neighborhood Hits	593	Target Neighborhood Hits	107	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

ANK3_HUMAN
θ value	2.36792 (rank : 340)	NC score	0.034807 (rank : 915)
Query Neighborhood Hits	593	Target Neighborhood Hits	853	Shared Neighborhood Hits	103
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

BAT2_MOUSE
θ value	2.36792 (rank : 341)	NC score	0.214635 (rank : 74)
Query Neighborhood Hits	593	Target Neighborhood Hits	947	Shared Neighborhood Hits	258
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CASC3_HUMAN
θ value	2.36792 (rank : 342)	NC score	0.093856 (rank : 398)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

COA2_HUMAN
θ value	2.36792 (rank : 343)	NC score	0.035445 (rank : 911)
Query Neighborhood Hits	593	Target Neighborhood Hits	184	Shared Neighborhood Hits	50
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

COIA1_HUMAN
θ value	2.36792 (rank : 344)	NC score	0.084252 (rank : 454)
Query Neighborhood Hits	593	Target Neighborhood Hits	447	Shared Neighborhood Hits	118
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DGKH_HUMAN
θ value	2.36792 (rank : 345)	NC score	0.027970 (rank : 951)
Query Neighborhood Hits	593	Target Neighborhood Hits	255	Shared Neighborhood Hits	26
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

E2F1_HUMAN
θ value	2.36792 (rank : 346)	NC score	0.018259 (rank : 1009)
Query Neighborhood Hits	593	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

GCP6_HUMAN
θ value	2.36792 (rank : 347)	NC score	0.035808 (rank : 908)
Query Neighborhood Hits	593	Target Neighborhood Hits	295	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

GLIS3_MOUSE
θ value	2.36792 (rank : 348)	NC score	0.017177 (rank : 1018)
Query Neighborhood Hits	593	Target Neighborhood Hits	861	Shared Neighborhood Hits	90
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

GRIN1_HUMAN
θ value	2.36792 (rank : 349)	NC score	0.111057 (rank : 295)
Query Neighborhood Hits	593	Target Neighborhood Hits	681	Shared Neighborhood Hits	135
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HMMR_MOUSE
θ value	2.36792 (rank : 350)	NC score	0.017879 (rank : 1012)
Query Neighborhood Hits	593	Target Neighborhood Hits	1178	Shared Neighborhood Hits	53
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HRX_HUMAN
θ value	2.36792 (rank : 351)	NC score	0.124485 (rank : 244)
Query Neighborhood Hits	593	Target Neighborhood Hits	825	Shared Neighborhood Hits	180
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HSF1_MOUSE
θ value	2.36792 (rank : 352)	NC score	0.046045 (rank : 862)
Query Neighborhood Hits	593	Target Neighborhood Hits	267	Shared Neighborhood Hits	71
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HXD1_MOUSE
θ value	2.36792 (rank : 353)	NC score	0.002531 (rank : 1098)
Query Neighborhood Hits	593	Target Neighborhood Hits	381	Shared Neighborhood Hits	15
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

LRTM4_HUMAN
θ value	2.36792 (rank : 354)	NC score	0.000117 (rank : 1103)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VH4	Gene names	LRRTM4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

M3K14_MOUSE
θ value	2.36792 (rank : 355)	NC score	0.008456 (rank : 1070)
Query Neighborhood Hits	593	Target Neighborhood Hits	889	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

MEF2D_HUMAN
θ value	2.36792 (rank : 356)	NC score	0.059252 (rank : 696)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	66
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2D_MOUSE
θ value	2.36792 (rank : 357)	NC score	0.059858 (rank : 687)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	59
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MRCKB_HUMAN
θ value	2.36792 (rank : 358)	NC score	0.010403 (rank : 1060)
Query Neighborhood Hits	593	Target Neighborhood Hits	2239	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYST3_MOUSE
θ value	2.36792 (rank : 359)	NC score	0.087502 (rank : 440)
Query Neighborhood Hits	593	Target Neighborhood Hits	688	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NRX2A_HUMAN
θ value	2.36792 (rank : 360)	NC score	0.042460 (rank : 875)
Query Neighborhood Hits	593	Target Neighborhood Hits	614	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	2.36792 (rank : 361)	NC score	0.057892 (rank : 726)
Query Neighborhood Hits	593	Target Neighborhood Hits	481	Shared Neighborhood Hits	89
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PRR12_HUMAN
θ value	2.36792 (rank : 362)	NC score	0.359294 (rank : 10)
Query Neighborhood Hits	593	Target Neighborhood Hits	460	Shared Neighborhood Hits	235
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

REC8L_MOUSE
θ value	2.36792 (rank : 363)	NC score	0.030222 (rank : 938)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C5S7, Q3UIN9, Q9JK52	Gene names	Rec8L1, Rec8
Domain Architecture
Description	Meiotic recombination protein REC8-like 1 (Cohesin Rec8p).

RECQ5_HUMAN
θ value	2.36792 (rank : 364)	NC score	0.040488 (rank : 882)
Query Neighborhood Hits	593	Target Neighborhood Hits	390	Shared Neighborhood Hits	75
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SPR1B_HUMAN
θ value	2.36792 (rank : 365)	NC score	0.072311 (rank : 548)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	23
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SRRM1_MOUSE
θ value	2.36792 (rank : 366)	NC score	0.308810 (rank : 20)
Query Neighborhood Hits	593	Target Neighborhood Hits	966	Shared Neighborhood Hits	268
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TARA_HUMAN
θ value	2.36792 (rank : 367)	NC score	0.142872 (rank : 196)
Query Neighborhood Hits	593	Target Neighborhood Hits	1626	Shared Neighborhood Hits	244
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

UROL1_MOUSE
θ value	2.36792 (rank : 368)	NC score	0.018073 (rank : 1011)
Query Neighborhood Hits	593	Target Neighborhood Hits	235	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

XCL2_HUMAN
θ value	2.36792 (rank : 369)	NC score	0.021064 (rank : 994)
Query Neighborhood Hits	593	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBD3	Gene names	XCL2, SCYC2
Domain Architecture
Description	Cytokine SCM-1 beta precursor (XCL2) (XC chemokine ligand 2).

3BP2_HUMAN
θ value	3.0926 (rank : 370)	NC score	0.098712 (rank : 363)
Query Neighborhood Hits	593	Target Neighborhood Hits	296	Shared Neighborhood Hits	92
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABI1_HUMAN
θ value	3.0926 (rank : 371)	NC score	0.052441 (rank : 809)
Query Neighborhood Hits	593	Target Neighborhood Hits	257	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ACD_HUMAN
θ value	3.0926 (rank : 372)	NC score	0.071955 (rank : 555)
Query Neighborhood Hits	593	Target Neighborhood Hits	143	Shared Neighborhood Hits	52
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

AIRE_MOUSE
θ value	3.0926 (rank : 373)	NC score	0.051402 (rank : 824)
Query Neighborhood Hits	593	Target Neighborhood Hits	196	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ATX2_HUMAN
θ value	3.0926 (rank : 374)	NC score	0.143907 (rank : 190)
Query Neighborhood Hits	593	Target Neighborhood Hits	375	Shared Neighborhood Hits	144
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BAG3_MOUSE
θ value	3.0926 (rank : 375)	NC score	0.168239 (rank : 133)
Query Neighborhood Hits	593	Target Neighborhood Hits	513	Shared Neighborhood Hits	163
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CCD1A_HUMAN
θ value	3.0926 (rank : 376)	NC score	0.083181 (rank : 461)
Query Neighborhood Hits	593	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

CEND3_MOUSE
θ value	3.0926 (rank : 377)	NC score	0.054688 (rank : 770)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CNOT4_HUMAN
θ value	3.0926 (rank : 378)	NC score	0.043772 (rank : 870)
Query Neighborhood Hits	593	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

ECM1_MOUSE
θ value	3.0926 (rank : 379)	NC score	0.066544 (rank : 616)
Query Neighborhood Hits	593	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

ERF_HUMAN
θ value	3.0926 (rank : 380)	NC score	0.037042 (rank : 904)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

IF4G1_MOUSE
θ value	3.0926 (rank : 381)	NC score	0.103667 (rank : 330)
Query Neighborhood Hits	593	Target Neighborhood Hits	534	Shared Neighborhood Hits	135
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

JPH2_MOUSE
θ value	3.0926 (rank : 382)	NC score	0.096989 (rank : 376)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MBB1A_HUMAN
θ value	3.0926 (rank : 383)	NC score	0.102717 (rank : 334)
Query Neighborhood Hits	593	Target Neighborhood Hits	665	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NDF1_HUMAN
θ value	3.0926 (rank : 384)	NC score	0.023148 (rank : 972)
Query Neighborhood Hits	593	Target Neighborhood Hits	186	Shared Neighborhood Hits	29
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NUCL_HUMAN
θ value	3.0926 (rank : 385)	NC score	0.018984 (rank : 1004)
Query Neighborhood Hits	593	Target Neighborhood Hits	415	Shared Neighborhood Hits	31
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

P73L_HUMAN
θ value	3.0926 (rank : 386)	NC score	0.021517 (rank : 988)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

PHLB2_MOUSE
θ value	3.0926 (rank : 387)	NC score	0.038472 (rank : 895)
Query Neighborhood Hits	593	Target Neighborhood Hits	1016	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PTPRN_MOUSE
θ value	3.0926 (rank : 388)	NC score	0.013838 (rank : 1040)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	51
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RHG25_HUMAN
θ value	3.0926 (rank : 389)	NC score	0.034661 (rank : 916)
Query Neighborhood Hits	593	Target Neighborhood Hits	550	Shared Neighborhood Hits	55
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SEM6A_HUMAN
θ value	3.0926 (rank : 390)	NC score	0.006976 (rank : 1079)
Query Neighborhood Hits	593	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6A_MOUSE
θ value	3.0926 (rank : 391)	NC score	0.007765 (rank : 1076)
Query Neighborhood Hits	593	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SYNP2_MOUSE
θ value	3.0926 (rank : 392)	NC score	0.088436 (rank : 433)
Query Neighborhood Hits	593	Target Neighborhood Hits	252	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TAF4_HUMAN
θ value	3.0926 (rank : 393)	NC score	0.286410 (rank : 24)
Query Neighborhood Hits	593	Target Neighborhood Hits	687	Shared Neighborhood Hits	224
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TLN1_HUMAN
θ value	3.0926 (rank : 394)	NC score	0.027274 (rank : 953)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
θ value	3.0926 (rank : 395)	NC score	0.022934 (rank : 975)
Query Neighborhood Hits	593	Target Neighborhood Hits	157	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	3.0926 (rank : 396)	NC score	0.023019 (rank : 974)
Query Neighborhood Hits	593	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TPO_MOUSE
θ value	3.0926 (rank : 397)	NC score	0.051256 (rank : 830)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	54
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TROAP_HUMAN
θ value	3.0926 (rank : 398)	NC score	0.141201 (rank : 201)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	97
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TULP1_MOUSE
θ value	3.0926 (rank : 399)	NC score	0.037223 (rank : 903)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

TXLNB_MOUSE
θ value	3.0926 (rank : 400)	NC score	0.032839 (rank : 927)
Query Neighborhood Hits	593	Target Neighborhood Hits	640	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

YAP1_HUMAN
θ value	3.0926 (rank : 401)	NC score	0.046156 (rank : 861)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	56
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZBT16_HUMAN
θ value	3.0926 (rank : 402)	NC score	0.004138 (rank : 1092)
Query Neighborhood Hits	593	Target Neighborhood Hits	1010	Shared Neighborhood Hits	65
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ASPP2_HUMAN
θ value	4.03905 (rank : 403)	NC score	0.070688 (rank : 568)
Query Neighborhood Hits	593	Target Neighborhood Hits	1156	Shared Neighborhood Hits	144
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

BCL6_MOUSE
θ value	4.03905 (rank : 404)	NC score	0.008636 (rank : 1068)
Query Neighborhood Hits	593	Target Neighborhood Hits	913	Shared Neighborhood Hits	69
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BORG1_MOUSE
θ value	4.03905 (rank : 405)	NC score	0.022008 (rank : 982)
Query Neighborhood Hits	593	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

CAF1B_MOUSE
θ value	4.03905 (rank : 406)	NC score	0.036084 (rank : 906)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CDC20_HUMAN
θ value	4.03905 (rank : 407)	NC score	0.008331 (rank : 1072)
Query Neighborhood Hits	593	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

DAF1_MOUSE
θ value	4.03905 (rank : 408)	NC score	0.018922 (rank : 1006)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

FOXJ2_HUMAN
θ value	4.03905 (rank : 409)	NC score	0.037309 (rank : 902)
Query Neighborhood Hits	593	Target Neighborhood Hits	239	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GORS2_MOUSE
θ value	4.03905 (rank : 410)	NC score	0.056376 (rank : 745)
Query Neighborhood Hits	593	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

INP5E_MOUSE
θ value	4.03905 (rank : 411)	NC score	0.029724 (rank : 940)
Query Neighborhood Hits	593	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

LAMC3_HUMAN
θ value	4.03905 (rank : 412)	NC score	0.012748 (rank : 1046)
Query Neighborhood Hits	593	Target Neighborhood Hits	588	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEF2B_MOUSE
θ value	4.03905 (rank : 413)	NC score	0.062863 (rank : 652)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	58
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

NFIP2_HUMAN
θ value	4.03905 (rank : 414)	NC score	0.024749 (rank : 963)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

NU214_HUMAN
θ value	4.03905 (rank : 415)	NC score	0.172694 (rank : 127)
Query Neighborhood Hits	593	Target Neighborhood Hits	657	Shared Neighborhood Hits	151
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OBF1_HUMAN
θ value	4.03905 (rank : 416)	NC score	0.053116 (rank : 799)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	55
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PER2_HUMAN
θ value	4.03905 (rank : 417)	NC score	0.058792 (rank : 705)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	61
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PF21A_HUMAN
θ value	4.03905 (rank : 418)	NC score	0.041601 (rank : 876)
Query Neighborhood Hits	593	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PP1R8_MOUSE
θ value	4.03905 (rank : 419)	NC score	0.023555 (rank : 969)
Query Neighborhood Hits	593	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

PRG4_HUMAN
θ value	4.03905 (rank : 420)	NC score	0.334333 (rank : 15)
Query Neighborhood Hits	593	Target Neighborhood Hits	764	Shared Neighborhood Hits	267
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRS10_HUMAN
θ value	4.03905 (rank : 421)	NC score	0.004696 (rank : 1090)
Query Neighborhood Hits	593	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	4.03905 (rank : 422)	NC score	0.004696 (rank : 1091)
Query Neighborhood Hits	593	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

RAI14_HUMAN
θ value	4.03905 (rank : 423)	NC score	0.019275 (rank : 1002)
Query Neighborhood Hits	593	Target Neighborhood Hits	1367	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	4.03905 (rank : 424)	NC score	0.023352 (rank : 970)
Query Neighborhood Hits	593	Target Neighborhood Hits	1505	Shared Neighborhood Hits	88
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RNF25_HUMAN
θ value	4.03905 (rank : 425)	NC score	0.045421 (rank : 864)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SRPK1_HUMAN
θ value	4.03905 (rank : 426)	NC score	0.013407 (rank : 1044)
Query Neighborhood Hits	593	Target Neighborhood Hits	706	Shared Neighborhood Hits	60
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SRRM2_HUMAN
θ value	4.03905 (rank : 427)	NC score	0.243343 (rank : 45)
Query Neighborhood Hits	593	Target Neighborhood Hits	1296	Shared Neighborhood Hits	296
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STON1_HUMAN
θ value	4.03905 (rank : 428)	NC score	0.021502 (rank : 989)
Query Neighborhood Hits	593	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TAB2_MOUSE
θ value	4.03905 (rank : 429)	NC score	0.030992 (rank : 932)
Query Neighborhood Hits	593	Target Neighborhood Hits	245	Shared Neighborhood Hits	42
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TITIN_HUMAN
θ value	4.03905 (rank : 430)	NC score	0.055338 (rank : 760)
Query Neighborhood Hits	593	Target Neighborhood Hits	2923	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TOP1_MOUSE
θ value	4.03905 (rank : 431)	NC score	0.026937 (rank : 954)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ZC11A_MOUSE
θ value	4.03905 (rank : 432)	NC score	0.039530 (rank : 887)
Query Neighborhood Hits	593	Target Neighborhood Hits	216	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

AFAD_HUMAN
θ value	5.27518 (rank : 433)	NC score	0.042545 (rank : 873)
Query Neighborhood Hits	593	Target Neighborhood Hits	689	Shared Neighborhood Hits	77
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AKAP2_HUMAN
θ value	5.27518 (rank : 434)	NC score	0.032440 (rank : 928)
Query Neighborhood Hits	593	Target Neighborhood Hits	507	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

BAZ2A_MOUSE
θ value	5.27518 (rank : 435)	NC score	0.094746 (rank : 390)
Query Neighborhood Hits	593	Target Neighborhood Hits	744	Shared Neighborhood Hits	156
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CAC1B_MOUSE
θ value	5.27518 (rank : 436)	NC score	0.023191 (rank : 971)
Query Neighborhood Hits	593	Target Neighborhood Hits	351	Shared Neighborhood Hits	66
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CBLB_HUMAN
θ value	5.27518 (rank : 437)	NC score	0.049165 (rank : 849)
Query Neighborhood Hits	593	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	5.27518 (rank : 438)	NC score	0.050506 (rank : 841)
Query Neighborhood Hits	593	Target Neighborhood Hits	277	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CDC20_MOUSE
θ value	5.27518 (rank : 439)	NC score	0.006670 (rank : 1081)
Query Neighborhood Hits	593	Target Neighborhood Hits	325	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

CEP68_HUMAN
θ value	5.27518 (rank : 440)	NC score	0.036060 (rank : 907)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CJ108_HUMAN
θ value	5.27518 (rank : 441)	NC score	0.067221 (rank : 608)
Query Neighborhood Hits	593	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CLSPN_HUMAN
θ value	5.27518 (rank : 442)	NC score	0.021311 (rank : 992)
Query Neighborhood Hits	593	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CNOT4_MOUSE
θ value	5.27518 (rank : 443)	NC score	0.058034 (rank : 724)
Query Neighborhood Hits	593	Target Neighborhood Hits	277	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

EP400_MOUSE
θ value	5.27518 (rank : 444)	NC score	0.090494 (rank : 414)
Query Neighborhood Hits	593	Target Neighborhood Hits	592	Shared Neighborhood Hits	177
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPN3_MOUSE
θ value	5.27518 (rank : 445)	NC score	0.063859 (rank : 641)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	90
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ETV3_MOUSE
θ value	5.27518 (rank : 446)	NC score	0.035074 (rank : 913)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FMN1B_MOUSE
θ value	5.27518 (rank : 447)	NC score	0.145693 (rank : 188)
Query Neighborhood Hits	593	Target Neighborhood Hits	447	Shared Neighborhood Hits	176
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

GA2L3_HUMAN
θ value	5.27518 (rank : 448)	NC score	0.086454 (rank : 446)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GNAS1_HUMAN
θ value	5.27518 (rank : 449)	NC score	0.069348 (rank : 584)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	80
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GP152_MOUSE
θ value	5.27518 (rank : 450)	NC score	0.034042 (rank : 921)
Query Neighborhood Hits	593	Target Neighborhood Hits	607	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

INSM1_MOUSE
θ value	5.27518 (rank : 451)	NC score	0.014707 (rank : 1034)
Query Neighborhood Hits	593	Target Neighborhood Hits	678	Shared Neighborhood Hits	47
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

IWS1_MOUSE
θ value	5.27518 (rank : 452)	NC score	0.095324 (rank : 383)
Query Neighborhood Hits	593	Target Neighborhood Hits	1258	Shared Neighborhood Hits	166
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JHD1A_HUMAN
θ value	5.27518 (rank : 453)	NC score	0.008379 (rank : 1071)
Query Neighborhood Hits	593	Target Neighborhood Hits	133	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

MAGD1_HUMAN
θ value	5.27518 (rank : 454)	NC score	0.038613 (rank : 893)
Query Neighborhood Hits	593	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MINT_HUMAN
θ value	5.27518 (rank : 455)	NC score	0.153890 (rank : 158)
Query Neighborhood Hits	593	Target Neighborhood Hits	1291	Shared Neighborhood Hits	242
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYH7_HUMAN
θ value	5.27518 (rank : 456)	NC score	0.019090 (rank : 1003)
Query Neighborhood Hits	593	Target Neighborhood Hits	1559	Shared Neighborhood Hits	68
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NCOR2_HUMAN
θ value	5.27518 (rank : 457)	NC score	0.140938 (rank : 203)
Query Neighborhood Hits	593	Target Neighborhood Hits	870	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	5.27518 (rank : 458)	NC score	0.112664 (rank : 287)
Query Neighborhood Hits	593	Target Neighborhood Hits	790	Shared Neighborhood Hits	151
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NCTR2_HUMAN
θ value	5.27518 (rank : 459)	NC score	0.028096 (rank : 949)
Query Neighborhood Hits	593	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

NFRKB_MOUSE
θ value	5.27518 (rank : 460)	NC score	0.122372 (rank : 249)
Query Neighborhood Hits	593	Target Neighborhood Hits	393	Shared Neighborhood Hits	120
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PLCG1_HUMAN
θ value	5.27518 (rank : 461)	NC score	0.061640 (rank : 666)
Query Neighborhood Hits	593	Target Neighborhood Hits	293	Shared Neighborhood Hits	29
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	5.27518 (rank : 462)	NC score	0.062506 (rank : 657)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	32
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PP1R8_HUMAN
θ value	5.27518 (rank : 463)	NC score	0.022031 (rank : 981)
Query Neighborhood Hits	593	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

PTN4_HUMAN
θ value	5.27518 (rank : 464)	NC score	0.009242 (rank : 1065)
Query Neighborhood Hits	593	Target Neighborhood Hits	303	Shared Neighborhood Hits	35
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RUNX1_HUMAN
θ value	5.27518 (rank : 465)	NC score	0.017528 (rank : 1014)
Query Neighborhood Hits	593	Target Neighborhood Hits	94	Shared Neighborhood Hits	22
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SASH1_MOUSE
θ value	5.27518 (rank : 466)	NC score	0.051793 (rank : 818)
Query Neighborhood Hits	593	Target Neighborhood Hits	263	Shared Neighborhood Hits	68
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SCAP_HUMAN
θ value	5.27518 (rank : 467)	NC score	0.020721 (rank : 996)
Query Neighborhood Hits	593	Target Neighborhood Hits	368	Shared Neighborhood Hits	46
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SFRS4_MOUSE
θ value	5.27518 (rank : 468)	NC score	0.037518 (rank : 899)
Query Neighborhood Hits	593	Target Neighborhood Hits	406	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SOX30_MOUSE
θ value	5.27518 (rank : 469)	NC score	0.068589 (rank : 592)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

STON2_HUMAN
θ value	5.27518 (rank : 470)	NC score	0.020230 (rank : 1000)
Query Neighborhood Hits	593	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

SYNPO_HUMAN
θ value	5.27518 (rank : 471)	NC score	0.095545 (rank : 381)
Query Neighborhood Hits	593	Target Neighborhood Hits	281	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TACC1_MOUSE
θ value	5.27518 (rank : 472)	NC score	0.035042 (rank : 914)
Query Neighborhood Hits	593	Target Neighborhood Hits	667	Shared Neighborhood Hits	71
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TENS1_HUMAN
θ value	5.27518 (rank : 473)	NC score	0.083176 (rank : 462)
Query Neighborhood Hits	593	Target Neighborhood Hits	400	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

THAP7_HUMAN
θ value	5.27518 (rank : 474)	NC score	0.028134 (rank : 948)
Query Neighborhood Hits	593	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

TLE4_HUMAN
θ value	5.27518 (rank : 475)	NC score	0.015704 (rank : 1027)
Query Neighborhood Hits	593	Target Neighborhood Hits	477	Shared Neighborhood Hits	57
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	5.27518 (rank : 476)	NC score	0.015624 (rank : 1029)
Query Neighborhood Hits	593	Target Neighborhood Hits	482	Shared Neighborhood Hits	58
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TRI17_MOUSE
θ value	5.27518 (rank : 477)	NC score	0.001829 (rank : 1100)
Query Neighborhood Hits	593	Target Neighborhood Hits	620	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRIP6_HUMAN
θ value	5.27518 (rank : 478)	NC score	0.039157 (rank : 890)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

USH2A_MOUSE
θ value	5.27518 (rank : 479)	NC score	0.015613 (rank : 1030)
Query Neighborhood Hits	593	Target Neighborhood Hits	626	Shared Neighborhood Hits	32
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

XCL1_HUMAN
θ value	5.27518 (rank : 480)	NC score	0.016736 (rank : 1022)
Query Neighborhood Hits	593	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P47992, Q52MA8	Gene names	XCL1, LTN, SCYC1
Domain Architecture
Description	Lymphotactin precursor (XCL1) (Cytokine SCM-1) (ATAC) (Lymphotaxin) (SCM-1-alpha) (Small inducible cytokine C1) (XC chemokine ligand 1).

ZF106_MOUSE
θ value	5.27518 (rank : 481)	NC score	0.020389 (rank : 999)
Query Neighborhood Hits	593	Target Neighborhood Hits	472	Shared Neighborhood Hits	53
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

ZN198_HUMAN
θ value	5.27518 (rank : 482)	NC score	0.010310 (rank : 1061)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

ZN385_HUMAN
θ value	5.27518 (rank : 483)	NC score	0.067549 (rank : 602)
Query Neighborhood Hits	593	Target Neighborhood Hits	614	Shared Neighborhood Hits	97
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN414_MOUSE
θ value	5.27518 (rank : 484)	NC score	0.028592 (rank : 947)
Query Neighborhood Hits	593	Target Neighborhood Hits	473	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

AAK1_MOUSE
θ value	6.88961 (rank : 485)	NC score	0.035178 (rank : 912)
Query Neighborhood Hits	593	Target Neighborhood Hits	1051	Shared Neighborhood Hits	125
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AHI1_HUMAN
θ value	6.88961 (rank : 486)	NC score	0.016073 (rank : 1025)
Query Neighborhood Hits	593	Target Neighborhood Hits	537	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ARNT_MOUSE
θ value	6.88961 (rank : 487)	NC score	0.025865 (rank : 960)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	38
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ATF7_HUMAN
θ value	6.88961 (rank : 488)	NC score	0.037379 (rank : 900)
Query Neighborhood Hits	593	Target Neighborhood Hits	333	Shared Neighborhood Hits	50
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	6.88961 (rank : 489)	NC score	0.032913 (rank : 926)
Query Neighborhood Hits	593	Target Neighborhood Hits	286	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATS4_HUMAN
θ value	6.88961 (rank : 490)	NC score	0.003936 (rank : 1093)
Query Neighborhood Hits	593	Target Neighborhood Hits	138	Shared Neighborhood Hits	6
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

BACH2_MOUSE
θ value	6.88961 (rank : 491)	NC score	0.003823 (rank : 1095)
Query Neighborhood Hits	593	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BAZ2A_HUMAN
θ value	6.88961 (rank : 492)	NC score	0.078753 (rank : 490)
Query Neighborhood Hits	593	Target Neighborhood Hits	780	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BCL6_HUMAN
θ value	6.88961 (rank : 493)	NC score	0.007888 (rank : 1075)
Query Neighborhood Hits	593	Target Neighborhood Hits	922	Shared Neighborhood Hits	63
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

BCOR_HUMAN
θ value	6.88961 (rank : 494)	NC score	0.039393 (rank : 888)
Query Neighborhood Hits	593	Target Neighborhood Hits	609	Shared Neighborhood Hits	94
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CENG3_HUMAN
θ value	6.88961 (rank : 495)	NC score	0.017522 (rank : 1015)
Query Neighborhood Hits	593	Target Neighborhood Hits	455	Shared Neighborhood Hits	28
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	6.88961 (rank : 496)	NC score	0.017639 (rank : 1013)
Query Neighborhood Hits	593	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CSPG2_MOUSE
θ value	6.88961 (rank : 497)	NC score	0.025303 (rank : 961)
Query Neighborhood Hits	593	Target Neighborhood Hits	711	Shared Neighborhood Hits	60
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CYH4_MOUSE
θ value	6.88961 (rank : 498)	NC score	0.026330 (rank : 959)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DAB1_MOUSE
θ value	6.88961 (rank : 499)	NC score	0.052767 (rank : 804)
Query Neighborhood Hits	593	Target Neighborhood Hits	145	Shared Neighborhood Hits	50
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

DCAK1_MOUSE
θ value	6.88961 (rank : 500)	NC score	-0.001816 (rank : 1106)
Query Neighborhood Hits	593	Target Neighborhood Hits	867	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

DLX4_MOUSE
θ value	6.88961 (rank : 501)	NC score	0.000829 (rank : 1102)
Query Neighborhood Hits	593	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

DOK1_HUMAN
θ value	6.88961 (rank : 502)	NC score	0.029173 (rank : 942)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

E2AK4_MOUSE
θ value	6.88961 (rank : 503)	NC score	-0.000044 (rank : 1104)
Query Neighborhood Hits	593	Target Neighborhood Hits	984	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

ES8L2_HUMAN
θ value	6.88961 (rank : 504)	NC score	0.014379 (rank : 1035)
Query Neighborhood Hits	593	Target Neighborhood Hits	193	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ETV1_MOUSE
θ value	6.88961 (rank : 505)	NC score	0.014866 (rank : 1033)
Query Neighborhood Hits	593	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

GRIN1_MOUSE
θ value	6.88961 (rank : 506)	NC score	0.146411 (rank : 184)
Query Neighborhood Hits	593	Target Neighborhood Hits	337	Shared Neighborhood Hits	115
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GTSE1_HUMAN
θ value	6.88961 (rank : 507)	NC score	0.099084 (rank : 359)
Query Neighborhood Hits	593	Target Neighborhood Hits	193	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

IASPP_MOUSE
θ value	6.88961 (rank : 508)	NC score	0.114536 (rank : 279)
Query Neighborhood Hits	593	Target Neighborhood Hits	1024	Shared Neighborhood Hits	192
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IC1_MOUSE
θ value	6.88961 (rank : 509)	NC score	0.006319 (rank : 1082)
Query Neighborhood Hits	593	Target Neighborhood Hits	164	Shared Neighborhood Hits	22
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

IRTF_HUMAN
θ value	6.88961 (rank : 510)	NC score	0.012686 (rank : 1047)
Query Neighborhood Hits	593	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

JIP2_HUMAN
θ value	6.88961 (rank : 511)	NC score	0.065137 (rank : 630)
Query Neighborhood Hits	593	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

LAMA5_HUMAN
θ value	6.88961 (rank : 512)	NC score	0.014131 (rank : 1036)
Query Neighborhood Hits	593	Target Neighborhood Hits	976	Shared Neighborhood Hits	61
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LIPS_HUMAN
θ value	6.88961 (rank : 513)	NC score	0.087335 (rank : 441)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	95
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MARE3_HUMAN
θ value	6.88961 (rank : 514)	NC score	0.010962 (rank : 1056)
Query Neighborhood Hits	593	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPY8, O00265, Q6FI15, Q9BZP7, Q9BZP8	Gene names	MAPRE3
Domain Architecture
Description	Microtubule-associated protein RP/EB family member 3 (End-binding protein 3) (EB3) (EB1 protein family member 3) (EBF3) (RP3).

MARE3_MOUSE
θ value	6.88961 (rank : 515)	NC score	0.010776 (rank : 1058)
Query Neighborhood Hits	593	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PER3, Q61167	Gene names	Mapre3
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein RP/EB family member 3 (End-binding protein 3) (EB3) (EB1 protein family member 3) (EBF3) (RP3).

MAST1_HUMAN
θ value	6.88961 (rank : 516)	NC score	0.013413 (rank : 1043)
Query Neighborhood Hits	593	Target Neighborhood Hits	1146	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MDN1_HUMAN
θ value	6.88961 (rank : 517)	NC score	0.034490 (rank : 919)
Query Neighborhood Hits	593	Target Neighborhood Hits	662	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYH6_HUMAN
θ value	6.88961 (rank : 518)	NC score	0.018945 (rank : 1005)
Query Neighborhood Hits	593	Target Neighborhood Hits	1426	Shared Neighborhood Hits	62
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYPN_HUMAN
θ value	6.88961 (rank : 519)	NC score	0.027723 (rank : 952)
Query Neighborhood Hits	593	Target Neighborhood Hits	418	Shared Neighborhood Hits	58
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

NECD_MOUSE
θ value	6.88961 (rank : 520)	NC score	0.038485 (rank : 894)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

P210L_HUMAN
θ value	6.88961 (rank : 521)	NC score	0.006759 (rank : 1080)
Query Neighborhood Hits	593	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

PF21B_MOUSE
θ value	6.88961 (rank : 522)	NC score	0.065857 (rank : 622)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	67
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PLXB1_HUMAN
θ value	6.88961 (rank : 523)	NC score	0.048756 (rank : 851)
Query Neighborhood Hits	593	Target Neighborhood Hits	360	Shared Neighborhood Hits	96
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PMS2_MOUSE
θ value	6.88961 (rank : 524)	NC score	0.010712 (rank : 1059)
Query Neighborhood Hits	593	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

REPS2_HUMAN
θ value	6.88961 (rank : 525)	NC score	0.044178 (rank : 868)
Query Neighborhood Hits	593	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

S23IP_MOUSE
θ value	6.88961 (rank : 526)	NC score	0.081200 (rank : 474)
Query Neighborhood Hits	593	Target Neighborhood Hits	363	Shared Neighborhood Hits	107
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SART3_HUMAN
θ value	6.88961 (rank : 527)	NC score	0.011759 (rank : 1054)
Query Neighborhood Hits	593	Target Neighborhood Hits	301	Shared Neighborhood Hits	22
SwissProt Accessions	Q15020, Q58F06, Q8IUS1, Q96J95	Gene names	SART3, KIAA0156, TIP110
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (hSART-3) (Tat-interacting protein of 110 kDa) (Tip110).

SART3_MOUSE
θ value	6.88961 (rank : 528)	NC score	0.012291 (rank : 1052)
Query Neighborhood Hits	593	Target Neighborhood Hits	341	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

SDK1_HUMAN
θ value	6.88961 (rank : 529)	NC score	0.009519 (rank : 1063)
Query Neighborhood Hits	593	Target Neighborhood Hits	511	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	6.88961 (rank : 530)	NC score	0.008761 (rank : 1066)
Query Neighborhood Hits	593	Target Neighborhood Hits	495	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SOS2_HUMAN
θ value	6.88961 (rank : 531)	NC score	0.047346 (rank : 856)
Query Neighborhood Hits	593	Target Neighborhood Hits	193	Shared Neighborhood Hits	60
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SP5_MOUSE
θ value	6.88961 (rank : 532)	NC score	0.013515 (rank : 1042)
Query Neighborhood Hits	593	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

SPEG_HUMAN
θ value	6.88961 (rank : 533)	NC score	0.054118 (rank : 778)
Query Neighborhood Hits	593	Target Neighborhood Hits	1762	Shared Neighborhood Hits	246
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TGIF_MOUSE
θ value	6.88961 (rank : 534)	NC score	0.007939 (rank : 1074)
Query Neighborhood Hits	593	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	P70284, Q921F9, Q99JS3	Gene names	Tgif
Domain Architecture
Description	5'-TG-3'-interacting factor (Homeobox protein TGIF).

TOP1_HUMAN
θ value	6.88961 (rank : 535)	NC score	0.022901 (rank : 976)
Query Neighborhood Hits	593	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TTBK1_HUMAN
θ value	6.88961 (rank : 536)	NC score	0.028914 (rank : 943)
Query Neighborhood Hits	593	Target Neighborhood Hits	1058	Shared Neighborhood Hits	118
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

YLPM1_HUMAN
θ value	6.88961 (rank : 537)	NC score	0.211284 (rank : 80)
Query Neighborhood Hits	593	Target Neighborhood Hits	670	Shared Neighborhood Hits	228
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZC11A_HUMAN
θ value	6.88961 (rank : 538)	NC score	0.039825 (rank : 883)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	28
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZC3H3_MOUSE
θ value	6.88961 (rank : 539)	NC score	0.038033 (rank : 897)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

3BP1_HUMAN
θ value	8.99809 (rank : 540)	NC score	0.147369 (rank : 180)
Query Neighborhood Hits	593	Target Neighborhood Hits	376	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ANC1_HUMAN
θ value	8.99809 (rank : 541)	NC score	0.008730 (rank : 1067)
Query Neighborhood Hits	593	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ARMX2_MOUSE
θ value	8.99809 (rank : 542)	NC score	0.088513 (rank : 430)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	93
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

AUTS2_HUMAN
θ value	8.99809 (rank : 543)	NC score	0.148857 (rank : 174)
Query Neighborhood Hits	593	Target Neighborhood Hits	342	Shared Neighborhood Hits	143
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BORG1_HUMAN
θ value	8.99809 (rank : 544)	NC score	0.022796 (rank : 977)
Query Neighborhood Hits	593	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

C2TA_HUMAN
θ value	8.99809 (rank : 545)	NC score	0.035681 (rank : 909)
Query Neighborhood Hits	593	Target Neighborhood Hits	190	Shared Neighborhood Hits	51
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

COIA1_MOUSE
θ value	8.99809 (rank : 546)	NC score	0.065262 (rank : 628)
Query Neighborhood Hits	593	Target Neighborhood Hits	481	Shared Neighborhood Hits	110
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CRSP7_HUMAN
θ value	8.99809 (rank : 547)	NC score	0.046748 (rank : 858)
Query Neighborhood Hits	593	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CS007_HUMAN
θ value	8.99809 (rank : 548)	NC score	0.134550 (rank : 220)
Query Neighborhood Hits	593	Target Neighborhood Hits	401	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS029_MOUSE
θ value	8.99809 (rank : 549)	NC score	0.020844 (rank : 995)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CSKI2_MOUSE
θ value	8.99809 (rank : 550)	NC score	0.084518 (rank : 453)
Query Neighborhood Hits	593	Target Neighborhood Hits	812	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CXA1_MOUSE
θ value	8.99809 (rank : 551)	NC score	0.000972 (rank : 1101)
Query Neighborhood Hits	593	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P23242	Gene names	Gja1, Cxn-43
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

DAB1_HUMAN
θ value	8.99809 (rank : 552)	NC score	0.070836 (rank : 565)
Query Neighborhood Hits	593	Target Neighborhood Hits	219	Shared Neighborhood Hits	72
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DCC_HUMAN
θ value	8.99809 (rank : 553)	NC score	0.021250 (rank : 993)
Query Neighborhood Hits	593	Target Neighborhood Hits	583	Shared Neighborhood Hits	42
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCP1B_HUMAN
θ value	8.99809 (rank : 554)	NC score	0.048658 (rank : 852)
Query Neighborhood Hits	593	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

DDEF1_MOUSE
θ value	8.99809 (rank : 555)	NC score	0.058449 (rank : 714)
Query Neighborhood Hits	593	Target Neighborhood Hits	592	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DUET_HUMAN
θ value	8.99809 (rank : 556)	NC score	0.003922 (rank : 1094)
Query Neighborhood Hits	593	Target Neighborhood Hits	1220	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ENL_HUMAN
θ value	8.99809 (rank : 557)	NC score	0.124426 (rank : 245)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	87
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

GA2L2_HUMAN
θ value	8.99809 (rank : 558)	NC score	0.048552 (rank : 853)
Query Neighborhood Hits	593	Target Neighborhood Hits	175	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GCM2_HUMAN
θ value	8.99809 (rank : 559)	NC score	0.015552 (rank : 1031)
Query Neighborhood Hits	593	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

GON4L_HUMAN
θ value	8.99809 (rank : 560)	NC score	0.056626 (rank : 738)
Query Neighborhood Hits	593	Target Neighborhood Hits	555	Shared Neighborhood Hits	86
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GON4L_MOUSE
θ value	8.99809 (rank : 561)	NC score	0.060924 (rank : 675)
Query Neighborhood Hits	593	Target Neighborhood Hits	455	Shared Neighborhood Hits	93
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HPS4_MOUSE
θ value	8.99809 (rank : 562)	NC score	0.023898 (rank : 968)
Query Neighborhood Hits	593	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

ITCH_HUMAN
θ value	8.99809 (rank : 563)	NC score	0.006017 (rank : 1085)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITF2_MOUSE
θ value	8.99809 (rank : 564)	NC score	0.009803 (rank : 1062)
Query Neighborhood Hits	593	Target Neighborhood Hits	154	Shared Neighborhood Hits	16
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

JHD2A_HUMAN
θ value	8.99809 (rank : 565)	NC score	0.016277 (rank : 1024)
Query Neighborhood Hits	593	Target Neighborhood Hits	118	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

K0310_HUMAN
θ value	8.99809 (rank : 566)	NC score	0.141267 (rank : 200)
Query Neighborhood Hits	593	Target Neighborhood Hits	420	Shared Neighborhood Hits	137
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1219_HUMAN
θ value	8.99809 (rank : 567)	NC score	0.021501 (rank : 990)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

K1219_MOUSE
θ value	8.99809 (rank : 568)	NC score	0.021439 (rank : 991)
Query Neighborhood Hits	593	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

M3K4_HUMAN
θ value	8.99809 (rank : 569)	NC score	-0.001245 (rank : 1105)
Query Neighborhood Hits	593	Target Neighborhood Hits	911	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

M3K9_HUMAN
θ value	8.99809 (rank : 570)	NC score	0.005618 (rank : 1087)
Query Neighborhood Hits	593	Target Neighborhood Hits	1123	Shared Neighborhood Hits	76
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MTR1L_HUMAN
θ value	8.99809 (rank : 571)	NC score	0.002965 (rank : 1097)
Query Neighborhood Hits	593	Target Neighborhood Hits	1180	Shared Neighborhood Hits	77
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NIPA_MOUSE
θ value	8.99809 (rank : 572)	NC score	0.034354 (rank : 920)
Query Neighborhood Hits	593	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

OSBL5_MOUSE
θ value	8.99809 (rank : 573)	NC score	0.005074 (rank : 1088)
Query Neighborhood Hits	593	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

P66A_HUMAN
θ value	8.99809 (rank : 574)	NC score	0.029769 (rank : 939)
Query Neighborhood Hits	593	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

PAPOG_HUMAN
θ value	8.99809 (rank : 575)	NC score	0.008593 (rank : 1069)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

PDLI5_HUMAN
θ value	8.99809 (rank : 576)	NC score	0.033707 (rank : 922)
Query Neighborhood Hits	593	Target Neighborhood Hits	322	Shared Neighborhood Hits	42
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PO6F2_MOUSE
θ value	8.99809 (rank : 577)	NC score	0.087785 (rank : 437)
Query Neighborhood Hits	593	Target Neighborhood Hits	639	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PSMF1_MOUSE
θ value	8.99809 (rank : 578)	NC score	0.013988 (rank : 1039)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

PTN14_HUMAN
θ value	8.99809 (rank : 579)	NC score	0.005670 (rank : 1086)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	8.99809 (rank : 580)	NC score	0.004786 (rank : 1089)
Query Neighborhood Hits	593	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

RAI1_HUMAN
θ value	8.99809 (rank : 581)	NC score	0.067038 (rank : 610)
Query Neighborhood Hits	593	Target Neighborhood Hits	360	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RFX1_HUMAN
θ value	8.99809 (rank : 582)	NC score	0.103060 (rank : 333)
Query Neighborhood Hits	593	Target Neighborhood Hits	256	Shared Neighborhood Hits	127
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SFPQ_MOUSE
θ value	8.99809 (rank : 583)	NC score	0.211003 (rank : 81)
Query Neighborhood Hits	593	Target Neighborhood Hits	958	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SNPC4_MOUSE
θ value	8.99809 (rank : 584)	NC score	0.052694 (rank : 805)
Query Neighborhood Hits	593	Target Neighborhood Hits	237	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SNTB2_MOUSE
θ value	8.99809 (rank : 585)	NC score	0.010778 (rank : 1057)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

STAT6_MOUSE
θ value	8.99809 (rank : 586)	NC score	0.021635 (rank : 984)
Query Neighborhood Hits	593	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

TAF6L_MOUSE
θ value	8.99809 (rank : 587)	NC score	0.028037 (rank : 950)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TAF9B_HUMAN
θ value	8.99809 (rank : 588)	NC score	0.021928 (rank : 983)
Query Neighborhood Hits	593	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

TENS4_MOUSE
θ value	8.99809 (rank : 589)	NC score	0.055289 (rank : 761)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TLN1_MOUSE
θ value	8.99809 (rank : 590)	NC score	0.021592 (rank : 987)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	22
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TOP2B_HUMAN
θ value	8.99809 (rank : 591)	NC score	0.009498 (rank : 1064)
Query Neighborhood Hits	593	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

WDR46_MOUSE
θ value	8.99809 (rank : 592)	NC score	0.042885 (rank : 872)
Query Neighborhood Hits	593	Target Neighborhood Hits	243	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZN575_MOUSE
θ value	8.99809 (rank : 593)	NC score	0.003754 (rank : 1096)
Query Neighborhood Hits	593	Target Neighborhood Hits	715	Shared Neighborhood Hits	35
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

3BP1_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.095121 (rank : 385)
Query Neighborhood Hits	593	Target Neighborhood Hits	238	Shared Neighborhood Hits	102
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.058903 (rank : 702)
Query Neighborhood Hits	593	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABI2_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.079290 (rank : 487)
Query Neighborhood Hits	593	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI3_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.058767 (rank : 706)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.053275 (rank : 796)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ACINU_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.080257 (rank : 481)
Query Neighborhood Hits	593	Target Neighborhood Hits	828	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.089551 (rank : 421)
Query Neighborhood Hits	593	Target Neighborhood Hits	712	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF1_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.120352 (rank : 258)
Query Neighborhood Hits	593	Target Neighborhood Hits	351	Shared Neighborhood Hits	112
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AFF4_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.075437 (rank : 513)
Query Neighborhood Hits	593	Target Neighborhood Hits	611	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.074149 (rank : 525)
Query Neighborhood Hits	593	Target Neighborhood Hits	581	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AKA12_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.069509 (rank : 581)
Query Neighborhood Hits	593	Target Neighborhood Hits	825	Shared Neighborhood Hits	91
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AKAP2_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.058705 (rank : 707)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ALEX_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.204970 (rank : 87)
Query Neighborhood Hits	593	Target Neighborhood Hits	361	Shared Neighborhood Hits	157
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.150255 (rank : 171)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	101
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALMS1_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.052646 (rank : 807)
Query Neighborhood Hits	593	Target Neighborhood Hits	356	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

AMELX_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.100346 (rank : 349)
Query Neighborhood Hits	593	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

AMELX_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.058383 (rank : 715)
Query Neighborhood Hits	593	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	P63277, P45559, P70592, Q61293	Gene names	Amelx, Amel
Domain Architecture	No domain graphic available
Description	Amelogenin, X isoform precursor (Leucine-rich amelogenin peptide) (LRAP).

AMELY_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.051982 (rank : 817)
Query Neighborhood Hits	593	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

AMOT_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.083844 (rank : 457)
Query Neighborhood Hits	593	Target Neighborhood Hits	712	Shared Neighborhood Hits	125
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AMPH_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.072717 (rank : 540)
Query Neighborhood Hits	593	Target Neighborhood Hits	455	Shared Neighborhood Hits	89
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.060259 (rank : 683)
Query Neighborhood Hits	593	Target Neighborhood Hits	291	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANTR1_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.074193 (rank : 523)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR1_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.078233 (rank : 494)
Query Neighborhood Hits	593	Target Neighborhood Hits	143	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

AP180_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.120955 (rank : 255)
Query Neighborhood Hits	593	Target Neighborhood Hits	183	Shared Neighborhood Hits	81
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

APC_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.083016 (rank : 463)
Query Neighborhood Hits	593	Target Neighborhood Hits	441	Shared Neighborhood Hits	78
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APS_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.069988 (rank : 576)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.055866 (rank : 751)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APXL_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.068028 (rank : 597)
Query Neighborhood Hits	593	Target Neighborhood Hits	553	Shared Neighborhood Hits	95
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARHGF_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.079384 (rank : 485)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	98
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1B_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.126527 (rank : 235)
Query Neighborhood Hits	593	Target Neighborhood Hits	567	Shared Neighborhood Hits	163
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARID2_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.076755 (rank : 506)
Query Neighborhood Hits	593	Target Neighborhood Hits	302	Shared Neighborhood Hits	74
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

ARMX2_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.054077 (rank : 779)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	43
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ASPP1_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.094271 (rank : 394)
Query Neighborhood Hits	593	Target Neighborhood Hits	956	Shared Neighborhood Hits	138
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATBF1_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.055359 (rank : 758)
Query Neighborhood Hits	593	Target Neighborhood Hits	1841	Shared Neighborhood Hits	223
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATF5_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.060415 (rank : 681)
Query Neighborhood Hits	593	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

ATX2L_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.145819 (rank : 187)
Query Neighborhood Hits	593	Target Neighborhood Hits	443	Shared Neighborhood Hits	152
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.112503 (rank : 289)
Query Neighborhood Hits	593	Target Neighborhood Hits	401	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

B4GN4_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.051374 (rank : 827)
Query Neighborhood Hits	593	Target Neighborhood Hits	131	Shared Neighborhood Hits	54
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BAG3_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.141115 (rank : 202)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	112
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.182492 (rank : 112)
Query Neighborhood Hits	593	Target Neighborhood Hits	321	Shared Neighborhood Hits	89
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.189571 (rank : 100)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	75
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BCAR3_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.058865 (rank : 704)
Query Neighborhood Hits	593	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.061604 (rank : 667)
Query Neighborhood Hits	593	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCAS1_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.055627 (rank : 756)
Query Neighborhood Hits	593	Target Neighborhood Hits	215	Shared Neighborhood Hits	49
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

BIN1_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.050343 (rank : 844)
Query Neighborhood Hits	593	Target Neighborhood Hits	283	Shared Neighborhood Hits	66
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BLNK_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.058307 (rank : 716)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BORG5_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.087074 (rank : 445)
Query Neighborhood Hits	593	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

BPTF_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.096301 (rank : 379)
Query Neighborhood Hits	593	Target Neighborhood Hits	786	Shared Neighborhood Hits	135
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD3_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.063067 (rank : 648)
Query Neighborhood Hits	593	Target Neighborhood Hits	369	Shared Neighborhood Hits	68
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.062297 (rank : 659)
Query Neighborhood Hits	593	Target Neighborhood Hits	402	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD8_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.067980 (rank : 598)
Query Neighborhood Hits	593	Target Neighborhood Hits	422	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CARD6_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.051222 (rank : 832)
Query Neighborhood Hits	593	Target Neighborhood Hits	145	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CASL_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.061968 (rank : 663)
Query Neighborhood Hits	593	Target Neighborhood Hits	259	Shared Neighborhood Hits	47
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.064663 (rank : 636)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	41
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CCDC4_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.053314 (rank : 794)
Query Neighborhood Hits	593	Target Neighborhood Hits	104	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

CCNK_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.218328 (rank : 65)
Query Neighborhood Hits	593	Target Neighborhood Hits	350	Shared Neighborhood Hits	189
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.184437 (rank : 110)
Query Neighborhood Hits	593	Target Neighborhood Hits	168	Shared Neighborhood Hits	92
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CDN1C_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.066806 (rank : 611)
Query Neighborhood Hits	593	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CDT1_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.053968 (rank : 783)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

CE025_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.076786 (rank : 505)
Query Neighborhood Hits	593	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

CEND3_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.056240 (rank : 746)
Query Neighborhood Hits	593	Target Neighborhood Hits	275	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.099421 (rank : 356)
Query Neighborhood Hits	593	Target Neighborhood Hits	84	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CEND_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.053275 (rank : 797)
Query Neighborhood Hits	593	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JKC6, Q9DBA0	Gene names	Cend1, Bm88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CENPT_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.051145 (rank : 833)
Query Neighborhood Hits	593	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

CITE4_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.088880 (rank : 425)
Query Neighborhood Hits	593	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CITE4_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.066262 (rank : 621)
Query Neighborhood Hits	593	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CIZ1_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.125924 (rank : 239)
Query Neighborhood Hits	593	Target Neighborhood Hits	359	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ012_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.088768 (rank : 427)
Query Neighborhood Hits	593	Target Neighborhood Hits	467	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CJ026_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.061225 (rank : 672)
Query Neighborhood Hits	593	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

CJ047_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.074139 (rank : 526)
Query Neighborhood Hits	593	Target Neighborhood Hits	164	Shared Neighborhood Hits	60
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CJ078_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.254790 (rank : 38)
Query Neighborhood Hits	593	Target Neighborhood Hits	559	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.108195 (rank : 307)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CN032_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.259773 (rank : 34)
Query Neighborhood Hits	593	Target Neighborhood Hits	267	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.253422 (rank : 40)
Query Neighborhood Hits	593	Target Neighborhood Hits	233	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.251430 (rank : 41)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	141
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNKR1_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.051075 (rank : 835)
Query Neighborhood Hits	593	Target Neighborhood Hits	154	Shared Neighborhood Hits	38
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNOT3_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.142160 (rank : 197)
Query Neighborhood Hits	593	Target Neighborhood Hits	425	Shared Neighborhood Hits	115
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.115800 (rank : 276)
Query Neighborhood Hits	593	Target Neighborhood Hits	504	Shared Neighborhood Hits	111
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO002_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.097425 (rank : 372)
Query Neighborhood Hits	593	Target Neighborhood Hits	387	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.155190 (rank : 155)
Query Neighborhood Hits	593	Target Neighborhood Hits	264	Shared Neighborhood Hits	111
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO1A1_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.068818 (rank : 591)
Query Neighborhood Hits	593	Target Neighborhood Hits	475	Shared Neighborhood Hits	101
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A1_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.071718 (rank : 558)
Query Neighborhood Hits	593	Target Neighborhood Hits	457	Shared Neighborhood Hits	104
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.073814 (rank : 533)
Query Neighborhood Hits	593	Target Neighborhood Hits	452	Shared Neighborhood Hits	107
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.073982 (rank : 532)
Query Neighborhood Hits	593	Target Neighborhood Hits	466	Shared Neighborhood Hits	109
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A4_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.052076 (rank : 815)
Query Neighborhood Hits	593	Target Neighborhood Hits	440	Shared Neighborhood Hits	87
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO4A5_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.077539 (rank : 502)
Query Neighborhood Hits	593	Target Neighborhood Hits	383	Shared Neighborhood Hits	96
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO5A2_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.050734 (rank : 839)
Query Neighborhood Hits	593	Target Neighborhood Hits	760	Shared Neighborhood Hits	104
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO8A2_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.058866 (rank : 703)
Query Neighborhood Hits	593	Target Neighborhood Hits	299	Shared Neighborhood Hits	73
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CO8A2_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.054371 (rank : 775)
Query Neighborhood Hits	593	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COAA1_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.058571 (rank : 711)
Query Neighborhood Hits	593	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COFA1_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.056566 (rank : 740)
Query Neighborhood Hits	593	Target Neighborhood Hits	292	Shared Neighborhood Hits	69
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

COGA1_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.061157 (rank : 673)
Query Neighborhood Hits	593	Target Neighborhood Hits	345	Shared Neighborhood Hits	74
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

COHA1_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.069489 (rank : 582)
Query Neighborhood Hits	593	Target Neighborhood Hits	400	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.062997 (rank : 650)
Query Neighborhood Hits	593	Target Neighborhood Hits	414	Shared Neighborhood Hits	97
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CPSF6_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.193042 (rank : 96)
Query Neighborhood Hits	593	Target Neighborhood Hits	359	Shared Neighborhood Hits	151
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.196052 (rank : 92)
Query Neighborhood Hits	593	Target Neighborhood Hits	356	Shared Neighborhood Hits	151
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRKL_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.064381 (rank : 638)
Query Neighborhood Hits	593	Target Neighborhood Hits	313	Shared Neighborhood Hits	34
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.060119 (rank : 684)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	30
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.071702 (rank : 559)
Query Neighborhood Hits	593	Target Neighborhood Hits	308	Shared Neighborhood Hits	35
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.072712 (rank : 541)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	40
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRTC1_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.107457 (rank : 316)
Query Neighborhood Hits	593	Target Neighborhood Hits	230	Shared Neighborhood Hits	81
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CSF1_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.051047 (rank : 836)
Query Neighborhood Hits	593	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

CSKI2_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.101027 (rank : 345)
Query Neighborhood Hits	593	Target Neighborhood Hits	747	Shared Neighborhood Hits	194
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT151_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.099183 (rank : 358)
Query Neighborhood Hits	593	Target Neighborhood Hits	382	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CT174_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.069450 (rank : 583)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

CTDP1_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.087663 (rank : 438)
Query Neighborhood Hits	593	Target Neighborhood Hits	416	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

CUTL1_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.050782 (rank : 838)
Query Neighborhood Hits	593	Target Neighborhood Hits	1574	Shared Neighborhood Hits	141
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DAB2_MOUSE
θ value	θ > 10 (rank : 701)	NC score	0.065045 (rank : 633)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

DACT1_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.063854 (rank : 642)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DAG1_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.078111 (rank : 496)
Query Neighborhood Hits	593	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

DAG1_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.078362 (rank : 493)
Query Neighborhood Hits	593	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

DAPP1_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.052920 (rank : 801)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DCP1A_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.068052 (rank : 596)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DDEF2_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.058196 (rank : 721)
Query Neighborhood Hits	593	Target Neighborhood Hits	599	Shared Neighborhood Hits	113
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.057677 (rank : 730)
Query Neighborhood Hits	593	Target Neighborhood Hits	625	Shared Neighborhood Hits	119
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKK_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.169963 (rank : 129)
Query Neighborhood Hits	593	Target Neighborhood Hits	378	Shared Neighborhood Hits	158
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.126585 (rank : 234)
Query Neighborhood Hits	593	Target Neighborhood Hits	784	Shared Neighborhood Hits	182
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.119351 (rank : 260)
Query Neighborhood Hits	593	Target Neighborhood Hits	839	Shared Neighborhood Hits	166
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DIAP2_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.056564 (rank : 741)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	95
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

DIDO1_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.101018 (rank : 346)
Query Neighborhood Hits	593	Target Neighborhood Hits	960	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DOT1L_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.116008 (rank : 273)
Query Neighborhood Hits	593	Target Neighborhood Hits	660	Shared Neighborhood Hits	138
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DREB_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.052366 (rank : 810)
Query Neighborhood Hits	593	Target Neighborhood Hits	450	Shared Neighborhood Hits	82
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DREB_MOUSE
θ value	θ > 10 (rank : 716)	NC score	0.059329 (rank : 695)
Query Neighborhood Hits	593	Target Neighborhood Hits	446	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

ELN_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.089110 (rank : 423)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

EMID2_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.052264 (rank : 811)
Query Neighborhood Hits	593	Target Neighborhood Hits	226	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EMSY_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.061579 (rank : 668)
Query Neighborhood Hits	593	Target Neighborhood Hits	296	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EMSY_MOUSE
θ value	θ > 10 (rank : 720)	NC score	0.070801 (rank : 566)
Query Neighborhood Hits	593	Target Neighborhood Hits	294	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ENAH_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.102674 (rank : 335)
Query Neighborhood Hits	593	Target Neighborhood Hits	784	Shared Neighborhood Hits	163
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.242658 (rank : 47)
Query Neighborhood Hits	593	Target Neighborhood Hits	919	Shared Neighborhood Hits	267
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENAM_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.057586 (rank : 733)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

ENAM_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.076396 (rank : 509)
Query Neighborhood Hits	593	Target Neighborhood Hits	229	Shared Neighborhood Hits	75
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

EP300_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.214369 (rank : 75)
Query Neighborhood Hits	593	Target Neighborhood Hits	821	Shared Neighborhood Hits	273
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EP400_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.096615 (rank : 377)
Query Neighborhood Hits	593	Target Neighborhood Hits	556	Shared Neighborhood Hits	180
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EPN1_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.092049 (rank : 407)
Query Neighborhood Hits	593	Target Neighborhood Hits	206	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

EPN1_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.088493 (rank : 431)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	90
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

ESX1L_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.054303 (rank : 776)
Query Neighborhood Hits	593	Target Neighborhood Hits	498	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

EVI2B_MOUSE
θ value	θ > 10 (rank : 730)	NC score	0.050215 (rank : 846)
Query Neighborhood Hits	593	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

EVL_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.063442 (rank : 645)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.051082 (rank : 834)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	60
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FBSH_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.052052 (rank : 816)
Query Neighborhood Hits	593	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

FHOD1_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.054687 (rank : 771)
Query Neighborhood Hits	593	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FIP1_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.054966 (rank : 764)
Query Neighborhood Hits	593	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

FMN1A_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.138940 (rank : 207)
Query Neighborhood Hits	593	Target Neighborhood Hits	423	Shared Neighborhood Hits	172
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN2_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.176142 (rank : 121)
Query Neighborhood Hits	593	Target Neighborhood Hits	484	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FMN2_MOUSE
θ value	θ > 10 (rank : 738)	NC score	0.157325 (rank : 151)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.164973 (rank : 141)
Query Neighborhood Hits	593	Target Neighborhood Hits	529	Shared Neighborhood Hits	197
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.107568 (rank : 315)
Query Neighborhood Hits	593	Target Neighborhood Hits	428	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FOG1_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.053723 (rank : 788)
Query Neighborhood Hits	593	Target Neighborhood Hits	981	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOG1_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.053668 (rank : 790)
Query Neighborhood Hits	593	Target Neighborhood Hits	1237	Shared Neighborhood Hits	199
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FYB_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.093809 (rank : 400)
Query Neighborhood Hits	593	Target Neighborhood Hits	379	Shared Neighborhood Hits	102
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

FYB_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.059860 (rank : 686)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	61
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

G3PT_MOUSE
θ value	θ > 10 (rank : 745)	NC score	0.056502 (rank : 743)
Query Neighborhood Hits	593	Target Neighborhood Hits	78	Shared Neighborhood Hits	55
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

GA2L1_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.051298 (rank : 828)
Query Neighborhood Hits	593	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GAK13_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.090718 (rank : 413)
Query Neighborhood Hits	593	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62686	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK14_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.093833 (rank : 399)
Query Neighborhood Hits	593	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P62687	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_16p3.3 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK15_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.101157 (rank : 344)
Query Neighborhood Hits	593	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P62688	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(I) Gag protein).

GAK17_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.101762 (rank : 341)
Query Neighborhood Hits	593	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK18_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.121216 (rank : 252)
Query Neighborhood Hits	593	Target Neighborhood Hits	116	Shared Neighborhood Hits	44
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK19_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.098635 (rank : 366)
Query Neighborhood Hits	593	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK9_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.101647 (rank : 342)
Query Neighborhood Hits	593	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

GCNL2_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.055783 (rank : 753)
Query Neighborhood Hits	593	Target Neighborhood Hits	159	Shared Neighborhood Hits	63
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.052152 (rank : 813)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

GCX1_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.054411 (rank : 774)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

GGN_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.235651 (rank : 53)
Query Neighborhood Hits	593	Target Neighborhood Hits	269	Shared Neighborhood Hits	147
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.247272 (rank : 44)
Query Neighborhood Hits	593	Target Neighborhood Hits	311	Shared Neighborhood Hits	174
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GNAS3_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.062155 (rank : 661)
Query Neighborhood Hits	593	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GNDS_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.078696 (rank : 491)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	90
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

GORS2_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.057628 (rank : 732)
Query Neighborhood Hits	593	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H8Y8, Q96I74, Q96K84, Q9H946, Q9UFW4	Gene names	GORASP2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) (Golgi phosphoprotein 6) (GOLPH6).

GP152_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.058450 (rank : 713)
Query Neighborhood Hits	593	Target Neighborhood Hits	636	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

GPTC8_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.061133 (rank : 674)
Query Neighborhood Hits	593	Target Neighborhood Hits	366	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRAP2_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.067494 (rank : 604)
Query Neighborhood Hits	593	Target Neighborhood Hits	304	Shared Neighborhood Hits	34
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.061342 (rank : 671)
Query Neighborhood Hits	593	Target Neighborhood Hits	297	Shared Neighborhood Hits	32
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.070712 (rank : 567)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.067821 (rank : 599)
Query Neighborhood Hits	593	Target Neighborhood Hits	309	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.057755 (rank : 728)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	33
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 769)	NC score	0.057754 (rank : 729)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	33
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GSCR1_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.318122 (rank : 19)
Query Neighborhood Hits	593	Target Neighborhood Hits	674	Shared Neighborhood Hits	287
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

GTSE1_MOUSE
θ value	θ > 10 (rank : 771)	NC score	0.069007 (rank : 588)
Query Neighborhood Hits	593	Target Neighborhood Hits	245	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

HCFC1_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.074985 (rank : 517)
Query Neighborhood Hits	593	Target Neighborhood Hits	331	Shared Neighborhood Hits	85
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.074054 (rank : 528)
Query Neighborhood Hits	593	Target Neighborhood Hits	348	Shared Neighborhood Hits	83
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCN2_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.074048 (rank : 529)
Query Neighborhood Hits	593	Target Neighborhood Hits	369	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.064107 (rank : 640)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	135
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.056204 (rank : 748)
Query Neighborhood Hits	593	Target Neighborhood Hits	303	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	θ > 10 (rank : 777)	NC score	0.060647 (rank : 678)
Query Neighborhood Hits	593	Target Neighborhood Hits	284	Shared Neighborhood Hits	118
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HGS_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.058956 (rank : 701)
Query Neighborhood Hits	593	Target Neighborhood Hits	589	Shared Neighborhood Hits	106
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HNRL1_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.054011 (rank : 782)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.066317 (rank : 620)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

HSH2D_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.052524 (rank : 808)
Query Neighborhood Hits	593	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.059800 (rank : 688)
Query Neighborhood Hits	593	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HXA3_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.051514 (rank : 822)
Query Neighborhood Hits	593	Target Neighborhood Hits	558	Shared Neighborhood Hits	149
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IASPP_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.113187 (rank : 285)
Query Neighborhood Hits	593	Target Neighborhood Hits	688	Shared Neighborhood Hits	158
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ICAL_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.051667 (rank : 819)
Query Neighborhood Hits	593	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ICAL_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.054776 (rank : 766)
Query Neighborhood Hits	593	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

IF35_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.088846 (rank : 426)
Query Neighborhood Hits	593	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF35_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.121843 (rank : 251)
Query Neighborhood Hits	593	Target Neighborhood Hits	210	Shared Neighborhood Hits	109
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF4G1_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.107342 (rank : 317)
Query Neighborhood Hits	593	Target Neighborhood Hits	347	Shared Neighborhood Hits	127
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IGEB_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.063497 (rank : 644)
Query Neighborhood Hits	593	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

IL3RB_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.087639 (rank : 439)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

INP5E_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.062582 (rank : 656)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

IQEC2_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.081360 (rank : 472)
Query Neighborhood Hits	593	Target Neighborhood Hits	403	Shared Neighborhood Hits	133
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IRS2_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.103188 (rank : 332)
Query Neighborhood Hits	593	Target Neighborhood Hits	262	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

IRS2_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.072961 (rank : 538)
Query Neighborhood Hits	593	Target Neighborhood Hits	248	Shared Neighborhood Hits	93
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IWS1_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.093078 (rank : 404)
Query Neighborhood Hits	593	Target Neighborhood Hits	1241	Shared Neighborhood Hits	156
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JADE2_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.052164 (rank : 812)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

K0460_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.091270 (rank : 411)
Query Neighborhood Hits	593	Target Neighborhood Hits	357	Shared Neighborhood Hits	102
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K0460_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.087238 (rank : 443)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	99
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K1210_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.050286 (rank : 845)
Query Neighborhood Hits	593	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

K1949_MOUSE
θ value	θ > 10 (rank : 801)	NC score	0.058156 (rank : 723)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

LAD1_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.111346 (rank : 294)
Query Neighborhood Hits	593	Target Neighborhood Hits	391	Shared Neighborhood Hits	91
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LCP2_MOUSE
θ value	θ > 10 (rank : 803)	NC score	0.089450 (rank : 422)
Query Neighborhood Hits	593	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LDB3_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.104731 (rank : 325)
Query Neighborhood Hits	593	Target Neighborhood Hits	497	Shared Neighborhood Hits	155
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.095452 (rank : 382)
Query Neighborhood Hits	593	Target Neighborhood Hits	510	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LEUK_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.076293 (rank : 510)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LEUK_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.068242 (rank : 594)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	43
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

LMBL3_MOUSE
θ value	θ > 10 (rank : 808)	NC score	0.053673 (rank : 789)
Query Neighborhood Hits	593	Target Neighborhood Hits	212	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

LNK_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.062849 (rank : 653)
Query Neighborhood Hits	593	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.068959 (rank : 590)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	14
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LPP_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.071528 (rank : 560)
Query Neighborhood Hits	593	Target Neighborhood Hits	247	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

LR37B_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.055277 (rank : 762)
Query Neighborhood Hits	593	Target Neighborhood Hits	392	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MADCA_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.166989 (rank : 137)
Query Neighborhood Hits	593	Target Neighborhood Hits	221	Shared Neighborhood Hits	109
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAGC1_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.085980 (rank : 449)
Query Neighborhood Hits	593	Target Neighborhood Hits	431	Shared Neighborhood Hits	136
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAML1_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.054716 (rank : 768)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAML3_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.070425 (rank : 571)
Query Neighborhood Hits	593	Target Neighborhood Hits	323	Shared Neighborhood Hits	78
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MAP1B_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.098593 (rank : 368)
Query Neighborhood Hits	593	Target Neighborhood Hits	903	Shared Neighborhood Hits	117
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP2_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.065261 (rank : 629)
Query Neighborhood Hits	593	Target Neighborhood Hits	348	Shared Neighborhood Hits	71
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MAP2_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.055663 (rank : 754)
Query Neighborhood Hits	593	Target Neighborhood Hits	342	Shared Neighborhood Hits	68
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MAP4_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.180131 (rank : 116)
Query Neighborhood Hits	593	Target Neighborhood Hits	409	Shared Neighborhood Hits	124
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.155933 (rank : 153)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.135321 (rank : 218)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	66
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAVS_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.106647 (rank : 320)
Query Neighborhood Hits	593	Target Neighborhood Hits	271	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBD6_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.282423 (rank : 26)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	164
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MECP2_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.057148 (rank : 735)
Query Neighborhood Hits	593	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MEGF9_HUMAN
θ value	θ > 10 (rank : 826)	NC score	0.074321 (rank : 521)
Query Neighborhood Hits	593	Target Neighborhood Hits	557	Shared Neighborhood Hits	120
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MILK1_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.135416 (rank : 217)
Query Neighborhood Hits	593	Target Neighborhood Hits	427	Shared Neighborhood Hits	149
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.081730 (rank : 470)
Query Neighborhood Hits	593	Target Neighborhood Hits	457	Shared Neighborhood Hits	105
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MKL1_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.059187 (rank : 698)
Query Neighborhood Hits	593	Target Neighborhood Hits	232	Shared Neighborhood Hits	77
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MKL2_HUMAN
θ value	θ > 10 (rank : 830)	NC score	0.063316 (rank : 646)
Query Neighborhood Hits	593	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MLL4_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.216025 (rank : 71)
Query Neighborhood Hits	593	Target Neighborhood Hits	722	Shared Neighborhood Hits	256
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MN1_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.096447 (rank : 378)
Query Neighborhood Hits	593	Target Neighborhood Hits	196	Shared Neighborhood Hits	69
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MORC2_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.054926 (rank : 765)
Query Neighborhood Hits	593	Target Neighborhood Hits	207	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

MTSS1_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.075141 (rank : 516)
Query Neighborhood Hits	593	Target Neighborhood Hits	504	Shared Neighborhood Hits	101
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.076499 (rank : 508)
Query Neighborhood Hits	593	Target Neighborhood Hits	592	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC13_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.128513 (rank : 232)
Query Neighborhood Hits	593	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.188873 (rank : 101)
Query Neighborhood Hits	593	Target Neighborhood Hits	388	Shared Neighborhood Hits	93
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.221065 (rank : 64)
Query Neighborhood Hits	593	Target Neighborhood Hits	906	Shared Neighborhood Hits	265
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.120298 (rank : 259)
Query Neighborhood Hits	593	Target Neighborhood Hits	1020	Shared Neighborhood Hits	181
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC7_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.353741 (rank : 13)
Query Neighborhood Hits	593	Target Neighborhood Hits	538	Shared Neighborhood Hits	242
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.103346 (rank : 331)
Query Neighborhood Hits	593	Target Neighborhood Hits	461	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYST3_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.092193 (rank : 406)
Query Neighborhood Hits	593	Target Neighborhood Hits	772	Shared Neighborhood Hits	161
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NACA_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.058541 (rank : 712)
Query Neighborhood Hits	593	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q13765, Q53A18, Q53G46	Gene names	NACA
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (Hom s 2.02).

NACA_MOUSE
θ value	θ > 10 (rank : 844)	NC score	0.059206 (rank : 697)
Query Neighborhood Hits	593	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q60817	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha (Alpha-NAC) (Alpha-NAC/1.9.2).

NCA11_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.063776 (rank : 643)
Query Neighborhood Hits	593	Target Neighborhood Hits	661	Shared Neighborhood Hits	125
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCK1_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.068995 (rank : 589)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	35
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.065090 (rank : 631)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOR1_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.055631 (rank : 755)
Query Neighborhood Hits	593	Target Neighborhood Hits	577	Shared Neighborhood Hits	104
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR1_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.055189 (rank : 763)
Query Neighborhood Hits	593	Target Neighborhood Hits	521	Shared Neighborhood Hits	95
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NELFA_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.122410 (rank : 248)
Query Neighborhood Hits	593	Target Neighborhood Hits	161	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.137566 (rank : 209)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NEUM_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.098606 (rank : 367)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.092020 (rank : 408)
Query Neighborhood Hits	593	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFH_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.097092 (rank : 375)
Query Neighborhood Hits	593	Target Neighborhood Hits	1242	Shared Neighborhood Hits	166
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NHS_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.066463 (rank : 617)
Query Neighborhood Hits	593	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NOLC1_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.169600 (rank : 130)
Query Neighborhood Hits	593	Target Neighborhood Hits	452	Shared Neighborhood Hits	109
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSD1_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.061489 (rank : 670)
Query Neighborhood Hits	593	Target Neighborhood Hits	427	Shared Neighborhood Hits	100
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.074130 (rank : 527)
Query Neighborhood Hits	593	Target Neighborhood Hits	472	Shared Neighborhood Hits	99
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NUMB_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.060343 (rank : 682)
Query Neighborhood Hits	593	Target Neighborhood Hits	112	Shared Neighborhood Hits	35
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	θ > 10 (rank : 860)	NC score	0.066657 (rank : 613)
Query Neighborhood Hits	593	Target Neighborhood Hits	91	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

NUP62_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.050677 (rank : 840)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	34
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

NUP62_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.051387 (rank : 826)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

ODO2_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.056446 (rank : 744)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

OGFR_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.107673 (rank : 312)
Query Neighborhood Hits	593	Target Neighborhood Hits	584	Shared Neighborhood Hits	101
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PAF49_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.091088 (rank : 412)
Query Neighborhood Hits	593	Target Neighborhood Hits	169	Shared Neighborhood Hits	61
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PARM1_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.079382 (rank : 486)
Query Neighborhood Hits	593	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PARM1_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.094277 (rank : 393)
Query Neighborhood Hits	593	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PB1_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.052957 (rank : 800)
Query Neighborhood Hits	593	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCQAP_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.175475 (rank : 125)
Query Neighborhood Hits	593	Target Neighborhood Hits	549	Shared Neighborhood Hits	171
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.147580 (rank : 179)
Query Neighborhood Hits	593	Target Neighborhood Hits	506	Shared Neighborhood Hits	158
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.118876 (rank : 262)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	132
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.110167 (rank : 297)
Query Neighborhood Hits	593	Target Neighborhood Hits	275	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDCD7_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.099693 (rank : 353)
Query Neighborhood Hits	593	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PDCD7_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.081986 (rank : 468)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PELP1_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.167415 (rank : 134)
Query Neighborhood Hits	593	Target Neighborhood Hits	596	Shared Neighborhood Hits	168
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 876)	NC score	0.161360 (rank : 144)
Query Neighborhood Hits	593	Target Neighborhood Hits	709	Shared Neighborhood Hits	178
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PER1_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.098910 (rank : 360)
Query Neighborhood Hits	593	Target Neighborhood Hits	215	Shared Neighborhood Hits	102
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.088074 (rank : 436)
Query Neighborhood Hits	593	Target Neighborhood Hits	235	Shared Neighborhood Hits	105
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.084140 (rank : 455)
Query Neighborhood Hits	593	Target Neighborhood Hits	479	Shared Neighborhood Hits	121
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PF21B_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.062188 (rank : 660)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PGCA_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.065330 (rank : 627)
Query Neighborhood Hits	593	Target Neighborhood Hits	821	Shared Neighborhood Hits	113
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PHAR2_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.088569 (rank : 429)
Query Neighborhood Hits	593	Target Neighborhood Hits	208	Shared Neighborhood Hits	62
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

PHC2_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.104106 (rank : 329)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PHC3_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.107628 (rank : 314)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PHLA1_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.067139 (rank : 609)
Query Neighborhood Hits	593	Target Neighborhood Hits	121	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

PI5PA_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.152441 (rank : 166)
Query Neighborhood Hits	593	Target Neighborhood Hits	331	Shared Neighborhood Hits	159
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PININ_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.055338 (rank : 759)
Query Neighborhood Hits	593	Target Neighborhood Hits	777	Shared Neighborhood Hits	100
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PKCB1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.054221 (rank : 777)
Query Neighborhood Hits	593	Target Neighborhood Hits	488	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PKHA4_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.077800 (rank : 500)
Query Neighborhood Hits	593	Target Neighborhood Hits	283	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.060655 (rank : 677)
Query Neighborhood Hits	593	Target Neighborhood Hits	591	Shared Neighborhood Hits	107
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLCG2_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.058632 (rank : 710)
Query Neighborhood Hits	593	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PO121_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.185002 (rank : 109)
Query Neighborhood Hits	593	Target Neighborhood Hits	344	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.163732 (rank : 142)
Query Neighborhood Hits	593	Target Neighborhood Hits	345	Shared Neighborhood Hits	112
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PO6F2_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.078213 (rank : 495)
Query Neighborhood Hits	593	Target Neighborhood Hits	618	Shared Neighborhood Hits	141
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PODXL_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.075937 (rank : 512)
Query Neighborhood Hits	593	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PODXL_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.066360 (rank : 619)
Query Neighborhood Hits	593	Target Neighborhood Hits	130	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PP1RA_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.066630 (rank : 614)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

PPRB_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.083384 (rank : 459)
Query Neighborhood Hits	593	Target Neighborhood Hits	311	Shared Neighborhood Hits	79
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PPRB_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.102493 (rank : 336)
Query Neighborhood Hits	593	Target Neighborhood Hits	354	Shared Neighborhood Hits	99
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRAX_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.094944 (rank : 388)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	61
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRB3_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.287951 (rank : 23)
Query Neighborhood Hits	593	Target Neighborhood Hits	318	Shared Neighborhood Hits	150
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.295302 (rank : 22)
Query Neighborhood Hits	593	Target Neighborhood Hits	330	Shared Neighborhood Hits	157
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRCC_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.113901 (rank : 282)
Query Neighborhood Hits	593	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

PRDM2_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.074028 (rank : 530)
Query Neighborhood Hits	593	Target Neighborhood Hits	1135	Shared Neighborhood Hits	184
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PRP1_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.329054 (rank : 16)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	183
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.355922 (rank : 12)
Query Neighborhood Hits	593	Target Neighborhood Hits	347	Shared Neighborhood Hits	175
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.137102 (rank : 211)
Query Neighborhood Hits	593	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.152340 (rank : 167)
Query Neighborhood Hits	593	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.081486 (rank : 471)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR13_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.211288 (rank : 79)
Query Neighborhood Hits	593	Target Neighborhood Hits	105	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.134790 (rank : 219)
Query Neighborhood Hits	593	Target Neighborhood Hits	54	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR8_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.112575 (rank : 288)
Query Neighborhood Hits	593	Target Neighborhood Hits	217	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PRRT1_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.097461 (rank : 371)
Query Neighborhood Hits	593	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT1_MOUSE
θ value	θ > 10 (rank : 914)	NC score	0.109524 (rank : 301)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT3_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.078004 (rank : 497)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PS1C2_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.122260 (rank : 250)
Query Neighborhood Hits	593	Target Neighborhood Hits	66	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.108884 (rank : 304)
Query Neighborhood Hits	593	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN23_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.116827 (rank : 270)
Query Neighborhood Hits	593	Target Neighborhood Hits	646	Shared Neighborhood Hits	207
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.112067 (rank : 293)
Query Neighborhood Hits	593	Target Neighborhood Hits	726	Shared Neighborhood Hits	232
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PYGO2_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.093752 (rank : 401)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

R3HD1_HUMAN
θ value	θ > 10 (rank : 921)	NC score	0.069888 (rank : 578)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

R3HD2_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.088968 (rank : 424)
Query Neighborhood Hits	593	Target Neighborhood Hits	397	Shared Neighborhood Hits	112
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RAI1_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.069190 (rank : 587)
Query Neighborhood Hits	593	Target Neighborhood Hits	344	Shared Neighborhood Hits	83
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RANB9_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.081978 (rank : 469)
Query Neighborhood Hits	593	Target Neighborhood Hits	179	Shared Neighborhood Hits	79
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RBBP6_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.072554 (rank : 542)
Query Neighborhood Hits	593	Target Neighborhood Hits	1135	Shared Neighborhood Hits	143
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 926)	NC score	0.070990 (rank : 563)
Query Neighborhood Hits	593	Target Neighborhood Hits	1014	Shared Neighborhood Hits	150
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBM12_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.106659 (rank : 319)
Query Neighborhood Hits	593	Target Neighborhood Hits	298	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.132189 (rank : 224)
Query Neighborhood Hits	593	Target Neighborhood Hits	313	Shared Neighborhood Hits	124
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM16_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.088352 (rank : 434)
Query Neighborhood Hits	593	Target Neighborhood Hits	300	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RD23B_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.054471 (rank : 773)
Query Neighborhood Hits	593	Target Neighborhood Hits	115	Shared Neighborhood Hits	35
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RD23B_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.083824 (rank : 458)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RERE_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.232877 (rank : 55)
Query Neighborhood Hits	593	Target Neighborhood Hits	779	Shared Neighborhood Hits	264
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.239813 (rank : 51)
Query Neighborhood Hits	593	Target Neighborhood Hits	785	Shared Neighborhood Hits	271
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

REXO1_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.072548 (rank : 543)
Query Neighborhood Hits	593	Target Neighborhood Hits	242	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RFIP1_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.066598 (rank : 615)
Query Neighborhood Hits	593	Target Neighborhood Hits	236	Shared Neighborhood Hits	68
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFX1_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.062596 (rank : 655)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	90
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

RIMB1_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.058268 (rank : 717)
Query Neighborhood Hits	593	Target Neighborhood Hits	1479	Shared Neighborhood Hits	168
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMS1_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.051397 (rank : 825)
Query Neighborhood Hits	593	Target Neighborhood Hits	437	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIN2_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.060520 (rank : 679)
Query Neighborhood Hits	593	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN2_MOUSE
θ value	θ > 10 (rank : 940)	NC score	0.074026 (rank : 531)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN3_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.140385 (rank : 204)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.155669 (rank : 154)
Query Neighborhood Hits	593	Target Neighborhood Hits	239	Shared Neighborhood Hits	135
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RL1D1_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.073358 (rank : 536)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	52
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

RNC_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.112366 (rank : 290)
Query Neighborhood Hits	593	Target Neighborhood Hits	176	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

RP1L1_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.110025 (rank : 298)
Query Neighborhood Hits	593	Target Neighborhood Hits	1072	Shared Neighborhood Hits	167
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RP3A_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.054727 (rank : 767)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPB1_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.159351 (rank : 146)
Query Neighborhood Hits	593	Target Neighborhood Hits	362	Shared Neighborhood Hits	140
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 948)	NC score	0.160608 (rank : 145)
Query Neighborhood Hits	593	Target Neighborhood Hits	363	Shared Neighborhood Hits	140
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RSF1_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.062141 (rank : 662)
Query Neighborhood Hits	593	Target Neighborhood Hits	539	Shared Neighborhood Hits	69
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RSMB_HUMAN
θ value	θ > 10 (rank : 950)	NC score	0.057330 (rank : 734)
Query Neighborhood Hits	593	Target Neighborhood Hits	117	Shared Neighborhood Hits	45
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

RSMN_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.067272 (rank : 606)
Query Neighborhood Hits	593	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	θ > 10 (rank : 952)	NC score	0.067272 (rank : 607)
Query Neighborhood Hits	593	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RTN1_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.058204 (rank : 720)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

RTN1_MOUSE
θ value	θ > 10 (rank : 954)	NC score	0.050385 (rank : 843)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

RTN4_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.113786 (rank : 283)
Query Neighborhood Hits	593	Target Neighborhood Hits	357	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RU1C_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.100918 (rank : 348)
Query Neighborhood Hits	593	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.102236 (rank : 337)
Query Neighborhood Hits	593	Target Neighborhood Hits	83	Shared Neighborhood Hits	49
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SC24B_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.059121 (rank : 700)
Query Neighborhood Hits	593	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SC24D_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.117750 (rank : 267)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	95
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SDC3_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.101003 (rank : 347)
Query Neighborhood Hits	593	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SDC3_MOUSE
θ value	θ > 10 (rank : 961)	NC score	0.105336 (rank : 324)
Query Neighborhood Hits	593	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SELPL_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.117034 (rank : 268)
Query Neighborhood Hits	593	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.188713 (rank : 102)
Query Neighborhood Hits	593	Target Neighborhood Hits	118	Shared Neighborhood Hits	73
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.193986 (rank : 94)
Query Neighborhood Hits	593	Target Neighborhood Hits	690	Shared Neighborhood Hits	209
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETBP_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.076521 (rank : 507)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.083233 (rank : 460)
Query Neighborhood Hits	593	Target Neighborhood Hits	352	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETD2_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.060014 (rank : 685)
Query Neighborhood Hits	593	Target Neighborhood Hits	412	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SF01_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.171555 (rank : 128)
Query Neighborhood Hits	593	Target Neighborhood Hits	287	Shared Neighborhood Hits	147
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.142028 (rank : 198)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	116
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A1_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.113028 (rank : 286)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	103
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	θ > 10 (rank : 971)	NC score	0.106386 (rank : 321)
Query Neighborhood Hits	593	Target Neighborhood Hits	198	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SF3A2_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.253698 (rank : 39)
Query Neighborhood Hits	593	Target Neighborhood Hits	263	Shared Neighborhood Hits	150
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 973)	NC score	0.257798 (rank : 37)
Query Neighborhood Hits	593	Target Neighborhood Hits	247	Shared Neighborhood Hits	149
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3B2_HUMAN
θ value	θ > 10 (rank : 974)	NC score	0.053400 (rank : 792)
Query Neighborhood Hits	593	Target Neighborhood Hits	157	Shared Neighborhood Hits	45
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SF3B4_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.082458 (rank : 467)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.186969 (rank : 107)
Query Neighborhood Hits	593	Target Neighborhood Hits	368	Shared Neighborhood Hits	142
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SFRS8_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.072420 (rank : 546)
Query Neighborhood Hits	593	Target Neighborhood Hits	166	Shared Neighborhood Hits	43
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SGIP1_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.146127 (rank : 186)
Query Neighborhood Hits	593	Target Neighborhood Hits	198	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 979)	NC score	0.145452 (rank : 189)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SH21A_HUMAN
θ value	θ > 10 (rank : 980)	NC score	0.077415 (rank : 503)
Query Neighborhood Hits	593	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 981)	NC score	0.072772 (rank : 539)
Query Neighborhood Hits	593	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 982)	NC score	0.080328 (rank : 479)
Query Neighborhood Hits	593	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 983)	NC score	0.057991 (rank : 725)
Query Neighborhood Hits	593	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.093697 (rank : 402)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 985)	NC score	0.091341 (rank : 409)
Query Neighborhood Hits	593	Target Neighborhood Hits	179	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH2D3_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.051569 (rank : 820)
Query Neighborhood Hits	593	Target Neighborhood Hits	174	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHAN1_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.115924 (rank : 274)
Query Neighborhood Hits	593	Target Neighborhood Hits	1041	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_MOUSE
θ value	θ > 10 (rank : 988)	NC score	0.071804 (rank : 557)
Query Neighborhood Hits	593	Target Neighborhood Hits	446	Shared Neighborhood Hits	93
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHC1_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.059748 (rank : 689)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 990)	NC score	0.056564 (rank : 742)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.074152 (rank : 524)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	25
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 992)	NC score	0.072089 (rank : 552)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.059545 (rank : 692)
Query Neighborhood Hits	593	Target Neighborhood Hits	155	Shared Neighborhood Hits	15
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 994)	NC score	0.062315 (rank : 658)
Query Neighborhood Hits	593	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SIN3A_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.052895 (rank : 803)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SMCA4_HUMAN
θ value	θ > 10 (rank : 996)	NC score	0.079722 (rank : 483)
Query Neighborhood Hits	593	Target Neighborhood Hits	597	Shared Neighborhood Hits	175
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMOO_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.108452 (rank : 306)
Query Neighborhood Hits	593	Target Neighborhood Hits	391	Shared Neighborhood Hits	128
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMR1_MOUSE
θ value	θ > 10 (rank : 998)	NC score	0.180325 (rank : 115)
Query Neighborhood Hits	593	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.187721 (rank : 105)
Query Neighborhood Hits	593	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SMR3B_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.088327 (rank : 435)
Query Neighborhood Hits	593	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SMRC1_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.074556 (rank : 518)
Query Neighborhood Hits	593	Target Neighborhood Hits	375	Shared Neighborhood Hits	99
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SMRC1_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.071452 (rank : 561)
Query Neighborhood Hits	593	Target Neighborhood Hits	459	Shared Neighborhood Hits	102
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SMRC2_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.098643 (rank : 365)
Query Neighborhood Hits	593	Target Neighborhood Hits	499	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.104163 (rank : 328)
Query Neighborhood Hits	593	Target Neighborhood Hits	487	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SOS1_MOUSE
θ value	θ > 10 (rank : 1005)	NC score	0.065745 (rank : 623)
Query Neighborhood Hits	593	Target Neighborhood Hits	281	Shared Neighborhood Hits	94
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SPAG8_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.052103 (rank : 814)
Query Neighborhood Hits	593	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

SPR1A_HUMAN
θ value	θ > 10 (rank : 1007)	NC score	0.067507 (rank : 603)
Query Neighborhood Hits	593	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPR2B_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.054011 (rank : 781)
Query Neighborhood Hits	593	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

SPR2D_HUMAN
θ value	θ > 10 (rank : 1009)	NC score	0.058636 (rank : 709)
Query Neighborhood Hits	593	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

SPR2D_MOUSE
θ value	θ > 10 (rank : 1010)	NC score	0.080473 (rank : 478)
Query Neighborhood Hits	593	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_MOUSE
θ value	θ > 10 (rank : 1011)	NC score	0.064493 (rank : 637)
Query Neighborhood Hits	593	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_MOUSE
θ value	θ > 10 (rank : 1012)	NC score	0.061647 (rank : 665)
Query Neighborhood Hits	593	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_HUMAN
θ value	θ > 10 (rank : 1013)	NC score	0.053734 (rank : 787)
Query Neighborhood Hits	593	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

SPR2G_MOUSE
θ value	θ > 10 (rank : 1014)	NC score	0.065061 (rank : 632)
Query Neighborhood Hits	593	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 1015)	NC score	0.105668 (rank : 323)
Query Neighborhood Hits	593	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 1016)	NC score	0.060450 (rank : 680)
Query Neighborhood Hits	593	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SPTA3_MOUSE
θ value	θ > 10 (rank : 1017)	NC score	0.094612 (rank : 392)
Query Neighborhood Hits	593	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

SRBP1_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.101865 (rank : 338)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRCA_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.064114 (rank : 639)
Query Neighborhood Hits	593	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SREC2_HUMAN
θ value	θ > 10 (rank : 1020)	NC score	0.057655 (rank : 731)
Query Neighborhood Hits	593	Target Neighborhood Hits	645	Shared Neighborhood Hits	109
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SSBP3_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.072193 (rank : 549)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	θ > 10 (rank : 1022)	NC score	0.072193 (rank : 550)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

SYN1_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.192291 (rank : 97)
Query Neighborhood Hits	593	Target Neighborhood Hits	419	Shared Neighborhood Hits	196
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.166811 (rank : 138)
Query Neighborhood Hits	593	Target Neighborhood Hits	363	Shared Neighborhood Hits	167
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYN2_HUMAN
θ value	θ > 10 (rank : 1025)	NC score	0.087307 (rank : 442)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYN2_MOUSE
θ value	θ > 10 (rank : 1026)	NC score	0.072029 (rank : 554)
Query Neighborhood Hits	593	Target Neighborhood Hits	183	Shared Neighborhood Hits	98
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SYN3_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.072399 (rank : 547)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	86
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

SYN3_MOUSE
θ value	θ > 10 (rank : 1028)	NC score	0.068359 (rank : 593)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

SYNJ1_HUMAN
θ value	θ > 10 (rank : 1029)	NC score	0.175777 (rank : 124)
Query Neighborhood Hits	593	Target Neighborhood Hits	498	Shared Neighborhood Hits	222
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ2_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.062657 (rank : 654)
Query Neighborhood Hits	593	Target Neighborhood Hits	136	Shared Neighborhood Hits	62
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNPO_MOUSE
θ value	θ > 10 (rank : 1031)	NC score	0.077769 (rank : 501)
Query Neighborhood Hits	593	Target Neighborhood Hits	242	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SYP2L_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.125321 (rank : 240)
Query Neighborhood Hits	593	Target Neighborhood Hits	400	Shared Neighborhood Hits	139
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	θ > 10 (rank : 1033)	NC score	0.101804 (rank : 339)
Query Neighborhood Hits	593	Target Neighborhood Hits	289	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

T22D2_HUMAN
θ value	θ > 10 (rank : 1034)	NC score	0.176887 (rank : 119)
Query Neighborhood Hits	593	Target Neighborhood Hits	250	Shared Neighborhood Hits	114
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

T2FA_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.053570 (rank : 791)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TAB3_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.088579 (rank : 428)
Query Neighborhood Hits	593	Target Neighborhood Hits	168	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TACC2_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.056094 (rank : 750)
Query Neighborhood Hits	593	Target Neighborhood Hits	856	Shared Neighborhood Hits	120
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.061511 (rank : 669)
Query Neighborhood Hits	593	Target Neighborhood Hits	774	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAF3_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.093252 (rank : 403)
Query Neighborhood Hits	593	Target Neighborhood Hits	568	Shared Neighborhood Hits	106
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 1040)	NC score	0.089820 (rank : 419)
Query Neighborhood Hits	593	Target Neighborhood Hits	463	Shared Neighborhood Hits	86
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF6_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.072034 (rank : 553)
Query Neighborhood Hits	593	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

TAF6_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.078644 (rank : 492)
Query Neighborhood Hits	593	Target Neighborhood Hits	110	Shared Neighborhood Hits	58
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

TARA_MOUSE
θ value	θ > 10 (rank : 1043)	NC score	0.109394 (rank : 302)
Query Neighborhood Hits	593	Target Neighborhood Hits	1133	Shared Neighborhood Hits	171
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.153131 (rank : 161)
Query Neighborhood Hits	593	Target Neighborhood Hits	448	Shared Neighborhood Hits	133
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.107629 (rank : 313)
Query Neighborhood Hits	593	Target Neighborhood Hits	414	Shared Neighborhood Hits	104
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCF20_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.053954 (rank : 784)
Query Neighborhood Hits	593	Target Neighborhood Hits	323	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 1047)	NC score	0.050924 (rank : 837)
Query Neighborhood Hits	593	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TCGAP_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.080267 (rank : 480)
Query Neighborhood Hits	593	Target Neighborhood Hits	409	Shared Neighborhood Hits	107
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCOF_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.148830 (rank : 175)
Query Neighborhood Hits	593	Target Neighborhood Hits	543	Shared Neighborhood Hits	109
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.179120 (rank : 117)
Query Neighborhood Hits	593	Target Neighborhood Hits	471	Shared Neighborhood Hits	112
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.094157 (rank : 395)
Query Neighborhood Hits	593	Target Neighborhood Hits	929	Shared Neighborhood Hits	159
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.099687 (rank : 354)
Query Neighborhood Hits	593	Target Neighborhood Hits	947	Shared Neighborhood Hits	168
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TENS4_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.070602 (rank : 569)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TFG_HUMAN
θ value	θ > 10 (rank : 1054)	NC score	0.075223 (rank : 515)
Query Neighborhood Hits	593	Target Neighborhood Hits	122	Shared Neighborhood Hits	51
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

TGON1_MOUSE
θ value	θ > 10 (rank : 1055)	NC score	0.054581 (rank : 772)
Query Neighborhood Hits	593	Target Neighborhood Hits	243	Shared Neighborhood Hits	42
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TGON2_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.059697 (rank : 690)
Query Neighborhood Hits	593	Target Neighborhood Hits	277	Shared Neighborhood Hits	48
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TIF1G_MOUSE
θ value	θ > 10 (rank : 1057)	NC score	0.051235 (rank : 831)
Query Neighborhood Hits	593	Target Neighborhood Hits	498	Shared Neighborhood Hits	98
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TM108_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.139176 (rank : 206)
Query Neighborhood Hits	593	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TM16H_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.053262 (rank : 798)
Query Neighborhood Hits	593	Target Neighborhood Hits	139	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TMAP1_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.118552 (rank : 263)
Query Neighborhood Hits	593	Target Neighborhood Hits	140	Shared Neighborhood Hits	52
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TP53B_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.055480 (rank : 757)
Query Neighborhood Hits	593	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRDN_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.074195 (rank : 522)
Query Neighborhood Hits	593	Target Neighborhood Hits	542	Shared Neighborhood Hits	66
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRI66_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.064911 (rank : 634)
Query Neighborhood Hits	593	Target Neighborhood Hits	479	Shared Neighborhood Hits	101
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 1064)	NC score	0.067562 (rank : 601)
Query Neighborhood Hits	593	Target Neighborhood Hits	491	Shared Neighborhood Hits	111
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TTC15_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.053368 (rank : 793)
Query Neighborhood Hits	593	Target Neighborhood Hits	112	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

TXND2_MOUSE
θ value	θ > 10 (rank : 1066)	NC score	0.073812 (rank : 534)
Query Neighborhood Hits	593	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP2L_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.061648 (rank : 664)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

UBP2L_MOUSE
θ value	θ > 10 (rank : 1068)	NC score	0.064902 (rank : 635)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	45
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

VASP_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.094717 (rank : 391)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	93
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.082671 (rank : 466)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	83
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VCX1_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.104206 (rank : 327)
Query Neighborhood Hits	593	Target Neighborhood Hits	129	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX2_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.069341 (rank : 585)
Query Neighborhood Hits	593	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H322, Q9P0H5	Gene names	VCX2, VCX2R, VCXB
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 2 (VCX-B protein) (Variably charged protein X-B) (Variable charge protein on X with two repeats) (VCX-2r).

VCX3_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.115273 (rank : 277)
Query Neighborhood Hits	593	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.108509 (rank : 305)
Query Neighborhood Hits	593	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VCY1_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.080118 (rank : 482)
Query Neighborhood Hits	593	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

VGF_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.059603 (rank : 691)
Query Neighborhood Hits	593	Target Neighborhood Hits	167	Shared Neighborhood Hits	42
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

WASF1_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.178730 (rank : 118)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	157
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 1078)	NC score	0.180992 (rank : 114)
Query Neighborhood Hits	593	Target Neighborhood Hits	261	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.217738 (rank : 66)
Query Neighborhood Hits	593	Target Neighborhood Hits	315	Shared Neighborhood Hits	194
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.138707 (rank : 208)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF3_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.126967 (rank : 233)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WASIP_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.357587 (rank : 11)
Query Neighborhood Hits	593	Target Neighborhood Hits	458	Shared Neighborhood Hits	231
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASL_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.214039 (rank : 76)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	184
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 1084)	NC score	0.228139 (rank : 59)
Query Neighborhood Hits	593	Target Neighborhood Hits	339	Shared Neighborhood Hits	191
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.148415 (rank : 177)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	117
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.149885 (rank : 172)
Query Neighborhood Hits	593	Target Neighborhood Hits	223	Shared Neighborhood Hits	126
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.240464 (rank : 48)
Query Neighborhood Hits	593	Target Neighborhood Hits	354	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.235860 (rank : 52)
Query Neighborhood Hits	593	Target Neighborhood Hits	362	Shared Neighborhood Hits	160
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.163491 (rank : 143)
Query Neighborhood Hits	593	Target Neighborhood Hits	273	Shared Neighborhood Hits	144
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WBS14_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.090462 (rank : 415)
Query Neighborhood Hits	593	Target Neighborhood Hits	171	Shared Neighborhood Hits	85
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

WDR33_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.053297 (rank : 795)
Query Neighborhood Hits	593	Target Neighborhood Hits	638	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

WNK2_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.070374 (rank : 572)
Query Neighborhood Hits	593	Target Neighborhood Hits	1407	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YETS2_MOUSE
θ value	θ > 10 (rank : 1093)	NC score	0.056211 (rank : 747)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

YLPM1_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.258528 (rank : 36)
Query Neighborhood Hits	593	Target Neighborhood Hits	505	Shared Neighborhood Hits	229
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZAN_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.098197 (rank : 369)
Query Neighborhood Hits	593	Target Neighborhood Hits	679	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.063003 (rank : 649)
Query Neighborhood Hits	593	Target Neighborhood Hits	808	Shared Neighborhood Hits	70
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZC313_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.058674 (rank : 708)
Query Neighborhood Hits	593	Target Neighborhood Hits	772	Shared Neighborhood Hits	91
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZCHC5_HUMAN
θ value	θ > 10 (rank : 1098)	NC score	0.074495 (rank : 519)
Query Neighborhood Hits	593	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

ZFHX2_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.051487 (rank : 823)
Query Neighborhood Hits	593	Target Neighborhood Hits	1178	Shared Neighborhood Hits	133
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZIM10_MOUSE
θ value	θ > 10 (rank : 1100)	NC score	0.089881 (rank : 416)
Query Neighborhood Hits	593	Target Neighborhood Hits	430	Shared Neighborhood Hits	105
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.060854 (rank : 676)
Query Neighborhood Hits	593	Target Neighborhood Hits	290	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN207_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.216256 (rank : 69)
Query Neighborhood Hits	593	Target Neighborhood Hits	326	Shared Neighborhood Hits	111
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN598_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.099864 (rank : 351)
Query Neighborhood Hits	593	Target Neighborhood Hits	339	Shared Neighborhood Hits	87
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZN598_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.057120 (rank : 736)
Query Neighborhood Hits	593	Target Neighborhood Hits	255	Shared Neighborhood Hits	50
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZYX_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.116024 (rank : 272)
Query Neighborhood Hits	593	Target Neighborhood Hits	387	Shared Neighborhood Hits	130
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

ZYX_MOUSE
θ value	θ > 10 (rank : 1106)	NC score	0.109876 (rank : 299)
Query Neighborhood Hits	593	Target Neighborhood Hits	347	Shared Neighborhood Hits	110
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

Hits sorted by NC score

RAPH1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	593	Target Neighborhood Hits	593	Shared Neighborhood Hits	593
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

AB1IP_HUMAN
NC score	0.822430 (rank : 2)	θ value	7.37397e-111 (rank : 2)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
NC score	0.803550 (rank : 3)	θ value	2.00813e-108 (rank : 3)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	101
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

GRB10_HUMAN
NC score	0.580603 (rank : 4)	θ value	9.20422e-37 (rank : 6)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
NC score	0.578610 (rank : 5)	θ value	5.584e-34 (rank : 7)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB7_HUMAN
NC score	0.559578 (rank : 6)	θ value	5.584e-34 (rank : 8)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB14_HUMAN
NC score	0.552818 (rank : 7)	θ value	2.19075e-38 (rank : 4)
Query Neighborhood Hits	593	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_MOUSE
NC score	0.545645 (rank : 8)	θ value	2.59387e-31 (rank : 9)
Query Neighborhood Hits	593	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRB14_MOUSE
NC score	0.541135 (rank : 9)	θ value	7.04741e-37 (rank : 5)
Query Neighborhood Hits	593	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

PRR12_HUMAN
NC score	0.359294 (rank : 10)	θ value	2.36792 (rank : 362)
Query Neighborhood Hits	593	Target Neighborhood Hits	460	Shared Neighborhood Hits	235
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

WASIP_HUMAN
NC score	0.357587 (rank : 11)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	593	Target Neighborhood Hits	458	Shared Neighborhood Hits	231
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRP2_MOUSE
NC score	0.355922 (rank : 12)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	593	Target Neighborhood Hits	347	Shared Neighborhood Hits	175
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

MUC7_HUMAN
NC score	0.353741 (rank : 13)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	593	Target Neighborhood Hits	538	Shared Neighborhood Hits	242
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

WASIP_MOUSE
NC score	0.346627 (rank : 14)	θ value	1.38821 (rank : 304)
Query Neighborhood Hits	593	Target Neighborhood Hits	392	Shared Neighborhood Hits	216
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PRG4_HUMAN
NC score	0.334333 (rank : 15)	θ value	4.03905 (rank : 420)
Query Neighborhood Hits	593	Target Neighborhood Hits	764	Shared Neighborhood Hits	267
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
NC score	0.329054 (rank : 16)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	183
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SRRM1_HUMAN
NC score	0.320544 (rank : 17)	θ value	0.21417 (rank : 171)
Query Neighborhood Hits	593	Target Neighborhood Hits	690	Shared Neighborhood Hits	220
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

NACAM_MOUSE
NC score	0.320426 (rank : 18)	θ value	5.43371e-13 (rank : 11)
Query Neighborhood Hits	593	Target Neighborhood Hits	1866	Shared Neighborhood Hits	373
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GSCR1_HUMAN
NC score	0.318122 (rank : 19)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	593	Target Neighborhood Hits	674	Shared Neighborhood Hits	287
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SRRM1_MOUSE
NC score	0.308810 (rank : 20)	θ value	2.36792 (rank : 366)
Query Neighborhood Hits	593	Target Neighborhood Hits	966	Shared Neighborhood Hits	268
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

WIRE_HUMAN
NC score	0.305482 (rank : 21)	θ value	0.279714 (rank : 184)
Query Neighborhood Hits	593	Target Neighborhood Hits	329	Shared Neighborhood Hits	192
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

PRB4S_HUMAN
NC score	0.295302 (rank : 22)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	593	Target Neighborhood Hits	330	Shared Neighborhood Hits	157
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRB3_HUMAN
NC score	0.287951 (rank : 23)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	593	Target Neighborhood Hits	318	Shared Neighborhood Hits	150
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

TAF4_HUMAN
NC score	0.286410 (rank : 24)	θ value	3.0926 (rank : 393)
Query Neighborhood Hits	593	Target Neighborhood Hits	687	Shared Neighborhood Hits	224
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WIRE_MOUSE
NC score	0.284569 (rank : 25)	θ value	0.62314 (rank : 228)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	178
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MBD6_HUMAN
NC score	0.282423 (rank : 26)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	164
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TARSH_HUMAN
NC score	0.282109 (rank : 27)	θ value	1.09739e-05 (rank : 26)
Query Neighborhood Hits	593	Target Neighborhood Hits	768	Shared Neighborhood Hits	206
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PRG4_MOUSE
NC score	0.280217 (rank : 28)	θ value	1.81305 (rank : 332)
Query Neighborhood Hits	593	Target Neighborhood Hits	624	Shared Neighborhood Hits	207
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CS016_HUMAN
NC score	0.277689 (rank : 29)	θ value	0.0330416 (rank : 103)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	146
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

MDC1_HUMAN
NC score	0.276766 (rank : 30)	θ value	1.06045e-08 (rank : 15)
Query Neighborhood Hits	593	Target Neighborhood Hits	1446	Shared Neighborhood Hits	280
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PCLO_HUMAN
NC score	0.269141 (rank : 31)	θ value	8.97725e-08 (rank : 16)
Query Neighborhood Hits	593	Target Neighborhood Hits	2046	Shared Neighborhood Hits	378
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MDC1_MOUSE
NC score	0.267162 (rank : 32)	θ value	4.45536e-07 (rank : 18)
Query Neighborhood Hits	593	Target Neighborhood Hits	998	Shared Neighborhood Hits	226
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BAT2_HUMAN
NC score	0.259841 (rank : 33)	θ value	0.163984 (rank : 153)
Query Neighborhood Hits	593	Target Neighborhood Hits	931	Shared Neighborhood Hits	275
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CN032_HUMAN
NC score	0.259773 (rank : 34)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	593	Target Neighborhood Hits	267	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

ATN1_HUMAN
NC score	0.259229 (rank : 35)	θ value	1.38821 (rank : 273)
Query Neighborhood Hits	593	Target Neighborhood Hits	676	Shared Neighborhood Hits	225
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

YLPM1_MOUSE
NC score	0.258528 (rank : 36)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	593	Target Neighborhood Hits	505	Shared Neighborhood Hits	229
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SF3A2_MOUSE
NC score	0.257798 (rank : 37)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	593	Target Neighborhood Hits	247	Shared Neighborhood Hits	149
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CJ078_MOUSE
NC score	0.254790 (rank : 38)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	593	Target Neighborhood Hits	559	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SF3A2_HUMAN
NC score	0.253698 (rank : 39)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	593	Target Neighborhood Hits	263	Shared Neighborhood Hits	150
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CN032_MOUSE
NC score	0.253422 (rank : 40)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	593	Target Neighborhood Hits	233	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
NC score	0.251430 (rank : 41)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	141
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

BSN_MOUSE
NC score	0.249863 (rank : 42)	θ value	0.00509761 (rank : 63)
Query Neighborhood Hits	593	Target Neighborhood Hits	2057	Shared Neighborhood Hits	348
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MLL2_HUMAN
NC score	0.247856 (rank : 43)	θ value	0.47712 (rank : 211)
Query Neighborhood Hits	593	Target Neighborhood Hits	1788	Shared Neighborhood Hits	361
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

GGN_MOUSE
NC score	0.247272 (rank : 44)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	593	Target Neighborhood Hits	311	Shared Neighborhood Hits	174
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SRRM2_HUMAN
NC score	0.243343 (rank : 45)	θ value	4.03905 (rank : 427)
Query Neighborhood Hits	593	Target Neighborhood Hits	1296	Shared Neighborhood Hits	296
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PCLO_MOUSE
NC score	0.242877 (rank : 46)	θ value	0.00665767 (rank : 73)
Query Neighborhood Hits	593	Target Neighborhood Hits	2275	Shared Neighborhood Hits	380
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ENAH_MOUSE
NC score	0.242658 (rank : 47)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	593	Target Neighborhood Hits	919	Shared Neighborhood Hits	267
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

WBP11_HUMAN
NC score	0.240464 (rank : 48)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	593	Target Neighborhood Hits	354	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

FA47A_HUMAN
NC score	0.240292 (rank : 49)	θ value	3.77169e-06 (rank : 22)
Query Neighborhood Hits	593	Target Neighborhood Hits	451	Shared Neighborhood Hits	129
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SON_HUMAN
NC score	0.240071 (rank : 50)	θ value	9.92553e-07 (rank : 19)
Query Neighborhood Hits	593	Target Neighborhood Hits	1568	Shared Neighborhood Hits	292
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RERE_MOUSE
NC score	0.239813 (rank : 51)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	593	Target Neighborhood Hits	785	Shared Neighborhood Hits	271
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

WBP11_MOUSE
NC score	0.235860 (rank : 52)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	593	Target Neighborhood Hits	362	Shared Neighborhood Hits	160
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

GGN_HUMAN
NC score	0.235651 (rank : 53)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	593	Target Neighborhood Hits	269	Shared Neighborhood Hits	147
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SRRM2_MOUSE
NC score	0.235426 (rank : 54)	θ value	0.0330416 (rank : 108)
Query Neighborhood Hits	593	Target Neighborhood Hits	1470	Shared Neighborhood Hits	289
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RERE_HUMAN
NC score	0.232877 (rank : 55)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	593	Target Neighborhood Hits	779	Shared Neighborhood Hits	264
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

BSN_HUMAN
NC score	0.231777 (rank : 56)	θ value	0.163984 (rank : 154)
Query Neighborhood Hits	593	Target Neighborhood Hits	1537	Shared Neighborhood Hits	303
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CK024_HUMAN
NC score	0.230729 (rank : 57)	θ value	0.0961366 (rank : 133)
Query Neighborhood Hits	593	Target Neighborhood Hits	408	Shared Neighborhood Hits	133
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SON_MOUSE
NC score	0.229018 (rank : 58)	θ value	0.00035302 (rank : 38)
Query Neighborhood Hits	593	Target Neighborhood Hits	957	Shared Neighborhood Hits	211
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

WASL_MOUSE
NC score	0.228139 (rank : 59)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	593	Target Neighborhood Hits	339	Shared Neighborhood Hits	191
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PRRT3_HUMAN
NC score	0.228089 (rank : 60)	θ value	3.19293e-05 (rank : 28)
Query Neighborhood Hits	593	Target Neighborhood Hits	998	Shared Neighborhood Hits	224
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MUC1_HUMAN
NC score	0.226951 (rank : 61)	θ value	3.88503e-19 (rank : 10)
Query Neighborhood Hits	593	Target Neighborhood Hits	975	Shared Neighborhood Hits	201
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_HUMAN
NC score	0.224846 (rank : 62)	θ value	0.00102713 (rank : 44)
Query Neighborhood Hits	593	Target Neighborhood Hits	1202	Shared Neighborhood Hits	291
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

K1802_HUMAN
NC score	0.223324 (rank : 63)	θ value	5.44631e-05 (rank : 29)
Query Neighborhood Hits	593	Target Neighborhood Hits	1378	Shared Neighborhood Hits	283
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MUC2_HUMAN
NC score	0.221065 (rank : 64)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	593	Target Neighborhood Hits	906	Shared Neighborhood Hits	265
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CCNK_MOUSE
NC score	0.218328 (rank : 65)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	593	Target Neighborhood Hits	350	Shared Neighborhood Hits	189
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

WASF2_MOUSE
NC score	0.217738 (rank : 66)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	593	Target Neighborhood Hits	315	Shared Neighborhood Hits	194
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

NCOA6_MOUSE
NC score	0.216517 (rank : 67)	θ value	0.0193708 (rank : 96)
Query Neighborhood Hits	593	Target Neighborhood Hits	1076	Shared Neighborhood Hits	258
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CBP_HUMAN
NC score	0.216410 (rank : 68)	θ value	0.0736092 (rank : 127)
Query Neighborhood Hits	593	Target Neighborhood Hits	941	Shared Neighborhood Hits	260
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ZN207_HUMAN
NC score	0.216256 (rank : 69)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	593	Target Neighborhood Hits	326	Shared Neighborhood Hits	111
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

BRD4_MOUSE
NC score	0.216129 (rank : 70)	θ value	0.21417 (rank : 165)
Query Neighborhood Hits	593	Target Neighborhood Hits	845	Shared Neighborhood Hits	241
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MLL4_HUMAN
NC score	0.216025 (rank : 71)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	593	Target Neighborhood Hits	722	Shared Neighborhood Hits	256
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

K1802_MOUSE
NC score	0.216006 (rank : 72)	θ value	5.08577e-11 (rank : 13)
Query Neighborhood Hits	593	Target Neighborhood Hits	1596	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASF4_HUMAN
NC score	0.215337 (rank : 73)	θ value	1.81305 (rank : 335)
Query Neighborhood Hits	593	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

BAT2_MOUSE
NC score	0.214635 (rank : 74)	θ value	2.36792 (rank : 341)
Query Neighborhood Hits	593	Target Neighborhood Hits	947	Shared Neighborhood Hits	258
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EP300_HUMAN
NC score	0.214369 (rank : 75)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	593	Target Neighborhood Hits	821	Shared Neighborhood Hits	273
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

WASL_HUMAN
NC score	0.214039 (rank : 76)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	184
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RGS3_MOUSE
NC score	0.213123 (rank : 77)	θ value	4.92598e-06 (rank : 23)
Query Neighborhood Hits	593	Target Neighborhood Hits	1621	Shared Neighborhood Hits	287
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

WASF2_HUMAN
NC score	0.212633 (rank : 78)	θ value	1.81305 (rank : 334)
Query Neighborhood Hits	593	Target Neighborhood Hits	280	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

PRR13_HUMAN
NC score	0.211288 (rank : 79)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	593	Target Neighborhood Hits	105	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

YLPM1_HUMAN
NC score	0.211284 (rank : 80)	θ value	6.88961 (rank : 537)
Query Neighborhood Hits	593	Target Neighborhood Hits	670	Shared Neighborhood Hits	228
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SFPQ_MOUSE
NC score	0.211003 (rank : 81)	θ value	8.99809 (rank : 583)
Query Neighborhood Hits	593	Target Neighborhood Hits	958	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CBP_MOUSE
NC score	0.210901 (rank : 82)	θ value	0.00228821 (rank : 56)
Query Neighborhood Hits	593	Target Neighborhood Hits	1051	Shared Neighborhood Hits	273
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CIC_HUMAN
NC score	0.210686 (rank : 83)	θ value	0.0113563 (rank : 83)
Query Neighborhood Hits	593	Target Neighborhood Hits	992	Shared Neighborhood Hits	263
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SFPQ_HUMAN
NC score	0.209561 (rank : 84)	θ value	0.813845 (rank : 251)
Query Neighborhood Hits	593	Target Neighborhood Hits	986	Shared Neighborhood Hits	253
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

FA47B_HUMAN
NC score	0.208457 (rank : 85)	θ value	0.00134147 (rank : 46)
Query Neighborhood Hits	593	Target Neighborhood Hits	431	Shared Neighborhood Hits	127
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

MLL3_HUMAN
NC score	0.208024 (rank : 86)	θ value	3.19293e-05 (rank : 27)
Query Neighborhood Hits	593	Target Neighborhood Hits	1644	Shared Neighborhood Hits	282
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ALEX_HUMAN
NC score	0.204970 (rank : 87)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	593	Target Neighborhood Hits	361	Shared Neighborhood Hits	157
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

OGFR_HUMAN
NC score	0.204024 (rank : 88)	θ value	0.000121331 (rank : 34)
Query Neighborhood Hits	593	Target Neighborhood Hits	1582	Shared Neighborhood Hits	257
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BRD4_HUMAN
NC score	0.203813 (rank : 89)	θ value	0.0193708 (rank : 92)
Query Neighborhood Hits	593	Target Neighborhood Hits	851	Shared Neighborhood Hits	250
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MAGE1_HUMAN
NC score	0.200905 (rank : 90)	θ value	5.62301e-10 (rank : 14)
Query Neighborhood Hits	593	Target Neighborhood Hits	1389	Shared Neighborhood Hits	281
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP4_HUMAN
NC score	0.199082 (rank : 91)	θ value	0.00134147 (rank : 48)
Query Neighborhood Hits	593	Target Neighborhood Hits	428	Shared Neighborhood Hits	119
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CPSF6_MOUSE
NC score	0.196052 (rank : 92)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	593	Target Neighborhood Hits	356	Shared Neighborhood Hits	151
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

MISS_MOUSE
NC score	0.194487 (rank : 93)	θ value	0.0252991 (rank : 99)
Query Neighborhood Hits	593	Target Neighborhood Hits	444	Shared Neighborhood Hits	133
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

SET1A_HUMAN
NC score	0.193986 (rank : 94)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	593	Target Neighborhood Hits	690	Shared Neighborhood Hits	209
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

BCL9_HUMAN
NC score	0.193525 (rank : 95)	θ value	0.0961366 (rank : 131)
Query Neighborhood Hits	593	Target Neighborhood Hits	1008	Shared Neighborhood Hits	222
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CPSF6_HUMAN
NC score	0.193042 (rank : 96)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	593	Target Neighborhood Hits	359	Shared Neighborhood Hits	151
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

SYN1_HUMAN
NC score	0.192291 (rank : 97)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	593	Target Neighborhood Hits	419	Shared Neighborhood Hits	196
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

LCP2_HUMAN
NC score	0.192219 (rank : 98)	θ value	0.00102713 (rank : 43)
Query Neighborhood Hits	593	Target Neighborhood Hits	531	Shared Neighborhood Hits	159
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MNT_HUMAN
NC score	0.189795 (rank : 99)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	593	Target Neighborhood Hits	496	Shared Neighborhood Hits	161
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

BASP_MOUSE
NC score	0.189571 (rank : 100)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	75
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MUC1_MOUSE
NC score	0.188873 (rank : 101)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	593	Target Neighborhood Hits	388	Shared Neighborhood Hits	93
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SELV_HUMAN
NC score	0.188713 (rank : 102)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	593	Target Neighborhood Hits	118	Shared Neighborhood Hits	73
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

CIC_MOUSE
NC score	0.188409 (rank : 103)	θ value	1.38821 (rank : 279)
Query Neighborhood Hits	593	Target Neighborhood Hits	742	Shared Neighborhood Hits	222
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MLL3_MOUSE
NC score	0.188208 (rank : 104)	θ value	3.41135e-07 (rank : 17)
Query Neighborhood Hits	593	Target Neighborhood Hits	1399	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SMR3A_HUMAN
NC score	0.187721 (rank : 105)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	593	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SELPL_MOUSE
NC score	0.187625 (rank : 106)	θ value	0.0330416 (rank : 107)
Query Neighborhood Hits	593	Target Neighborhood Hits	588	Shared Neighborhood Hits	149
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SFR15_HUMAN
NC score	0.186969 (rank : 107)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	593	Target Neighborhood Hits	368	Shared Neighborhood Hits	142
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

BCL9_MOUSE
NC score	0.185200 (rank : 108)	θ value	1.38821 (rank : 277)
Query Neighborhood Hits	593	Target Neighborhood Hits	770	Shared Neighborhood Hits	201
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PO121_HUMAN
NC score	0.185002 (rank : 109)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	593	Target Neighborhood Hits	344	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CDN1C_HUMAN
NC score	0.184437 (rank : 110)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	593	Target Neighborhood Hits	168	Shared Neighborhood Hits	92
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

TM108_MOUSE
NC score	0.183607 (rank : 111)	θ value	0.00665767 (rank : 76)
Query Neighborhood Hits	593	Target Neighborhood Hits	336	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

BASP_HUMAN
NC score	0.182492 (rank : 112)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	593	Target Neighborhood Hits	321	Shared Neighborhood Hits	89
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_MOUSE
NC score	0.181518 (rank : 113)	θ value	0.62314 (rank : 219)
Query Neighborhood Hits	593	Target Neighborhood Hits	518	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

WASF1_MOUSE
NC score	0.180992 (rank : 114)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	593	Target Neighborhood Hits	261	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

SMR1_MOUSE
NC score	0.180325 (rank : 115)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	593	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

MAP4_MOUSE
NC score	0.180131 (rank : 116)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	593	Target Neighborhood Hits	409	Shared Neighborhood Hits	124
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TCOF_MOUSE
NC score	0.179120 (rank : 117)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	593	Target Neighborhood Hits	471	Shared Neighborhood Hits	112
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

WASF1_HUMAN
NC score	0.178730 (rank : 118)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	157
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

T22D2_HUMAN
NC score	0.176887 (rank : 119)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	593	Target Neighborhood Hits	250	Shared Neighborhood Hits	114
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SYNJ1_MOUSE
NC score	0.176665 (rank : 120)	θ value	0.0961366 (rank : 145)
Query Neighborhood Hits	593	Target Neighborhood Hits	516	Shared Neighborhood Hits	220
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

FMN2_HUMAN
NC score	0.176142 (rank : 121)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	593	Target Neighborhood Hits	484	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

TXND2_HUMAN
NC score	0.176087 (rank : 122)	θ value	0.000270298 (rank : 36)
Query Neighborhood Hits	593	Target Neighborhood Hits	793	Shared Neighborhood Hits	148
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MNT_MOUSE
NC score	0.175856 (rank : 123)	θ value	1.81305 (rank : 325)
Query Neighborhood Hits	593	Target Neighborhood Hits	432	Shared Neighborhood Hits	145
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SYNJ1_HUMAN
NC score	0.175777 (rank : 124)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	593	Target Neighborhood Hits	498	Shared Neighborhood Hits	222
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PCQAP_HUMAN
NC score	0.175475 (rank : 125)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	593	Target Neighborhood Hits	549	Shared Neighborhood Hits	171
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

MILK1_MOUSE
NC score	0.174316 (rank : 126)	θ value	0.125558 (rank : 149)
Query Neighborhood Hits	593	Target Neighborhood Hits	788	Shared Neighborhood Hits	214
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NU214_HUMAN
NC score	0.172694 (rank : 127)	θ value	4.03905 (rank : 415)
Query Neighborhood Hits	593	Target Neighborhood Hits	657	Shared Neighborhood Hits	151
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SF01_HUMAN
NC score	0.171555 (rank : 128)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	593	Target Neighborhood Hits	287	Shared Neighborhood Hits	147
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

DGKK_HUMAN
NC score	0.169963 (rank : 129)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	593	Target Neighborhood Hits	378	Shared Neighborhood Hits	158
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

NOLC1_HUMAN
NC score	0.169600 (rank : 130)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	593	Target Neighborhood Hits	452	Shared Neighborhood Hits	109
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PI5PA_HUMAN
NC score	0.169086 (rank : 131)	θ value	1.06291 (rank : 266)
Query Neighborhood Hits	593	Target Neighborhood Hits	749	Shared Neighborhood Hits	224
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ARI1A_HUMAN
NC score	0.168662 (rank : 132)	θ value	1.81305 (rank : 309)
Query Neighborhood Hits	593	Target Neighborhood Hits	787	Shared Neighborhood Hits	206
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAG3_MOUSE
NC score	0.168239 (rank : 133)	θ value	3.0926 (rank : 375)
Query Neighborhood Hits	593	Target Neighborhood Hits	513	Shared Neighborhood Hits	163
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PELP1_HUMAN
NC score	0.167415 (rank : 134)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	593	Target Neighborhood Hits	596	Shared Neighborhood Hits	168
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

NFH_MOUSE
NC score	0.167373 (rank : 135)	θ value	3.89403e-11 (rank : 12)
Query Neighborhood Hits	593	Target Neighborhood Hits	2247	Shared Neighborhood Hits	306
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SC24C_HUMAN
NC score	0.166994 (rank : 136)	θ value	0.00665767 (rank : 74)
Query Neighborhood Hits	593	Target Neighborhood Hits	662	Shared Neighborhood Hits	152
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MADCA_HUMAN
NC score	0.166989 (rank : 137)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	593	Target Neighborhood Hits	221	Shared Neighborhood Hits	109
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SYN1_MOUSE
NC score	0.166811 (rank : 138)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	593	Target Neighborhood Hits	363	Shared Neighborhood Hits	167
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CRTC1_HUMAN
NC score	0.166670 (rank : 139)	θ value	1.38821 (rank : 280)
Query Neighborhood Hits	593	Target Neighborhood Hits	319	Shared Neighborhood Hits	135
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CO039_MOUSE
NC score	0.166300 (rank : 140)	θ value	0.0961366 (rank : 134)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	158
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

FMNL_HUMAN
NC score	0.164973 (rank : 141)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	593	Target Neighborhood Hits	529	Shared Neighborhood Hits	197
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PO121_MOUSE
NC score	0.163732 (rank : 142)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	593	Target Neighborhood Hits	345	Shared Neighborhood Hits	112
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

WBS14_HUMAN
NC score	0.163491 (rank : 143)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	593	Target Neighborhood Hits	273	Shared Neighborhood Hits	144
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

PELP1_MOUSE
NC score	0.161360 (rank : 144)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	593	Target Neighborhood Hits	709	Shared Neighborhood Hits	178
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RPB1_MOUSE
NC score	0.160608 (rank : 145)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	593	Target Neighborhood Hits	363	Shared Neighborhood Hits	140
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.159351 (rank : 146)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	593	Target Neighborhood Hits	362	Shared Neighborhood Hits	140
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

K1683_HUMAN
NC score	0.158855 (rank : 147)	θ value	0.00298849 (rank : 59)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

TAU_MOUSE
NC score	0.158765 (rank : 148)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	593	Target Neighborhood Hits	502	Shared Neighborhood Hits	133
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

MINT_MOUSE
NC score	0.157834 (rank : 149)	θ value	0.0330416 (rank : 106)
Query Neighborhood Hits	593	Target Neighborhood Hits	1514	Shared Neighborhood Hits	244
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUCDL_HUMAN
NC score	0.157353 (rank : 150)	θ value	1.38821 (rank : 293)
Query Neighborhood Hits	593	Target Neighborhood Hits	777	Shared Neighborhood Hits	175
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

FMN2_MOUSE
NC score	0.157325 (rank : 151)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

CS007_MOUSE
NC score	0.156212 (rank : 152)	θ value	0.813845 (rank : 233)
Query Neighborhood Hits	593	Target Neighborhood Hits	464	Shared Neighborhood Hits	147
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

MARCS_HUMAN
NC score	0.155933 (rank : 153)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

RIN3_MOUSE
NC score	0.155669 (rank : 154)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	593	Target Neighborhood Hits	239	Shared Neighborhood Hits	135
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CO039_HUMAN
NC score	0.155190 (rank : 155)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	593	Target Neighborhood Hits	264	Shared Neighborhood Hits	111
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

RGS3_HUMAN
NC score	0.154341 (rank : 156)	θ value	7.1131e-05 (rank : 30)
Query Neighborhood Hits	593	Target Neighborhood Hits	1375	Shared Neighborhood Hits	232
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PHC2_HUMAN
NC score	0.154086 (rank : 157)	θ value	9.29e-05 (rank : 32)
Query Neighborhood Hits	593	Target Neighborhood Hits	388	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

MINT_HUMAN
NC score	0.153890 (rank : 158)	θ value	5.27518 (rank : 455)
Query Neighborhood Hits	593	Target Neighborhood Hits	1291	Shared Neighborhood Hits	242
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BAT3_HUMAN
NC score	0.153777 (rank : 159)	θ value	0.62314 (rank : 218)
Query Neighborhood Hits	593	Target Neighborhood Hits	490	Shared Neighborhood Hits	127
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

GAK5_HUMAN
NC score	0.153561 (rank : 160)	θ value	0.00175202 (rank : 52)
Query Neighborhood Hits	593	Target Neighborhood Hits	429	Shared Neighborhood Hits	105
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TAU_HUMAN
NC score	0.153131 (rank : 161)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	593	Target Neighborhood Hits	448	Shared Neighborhood Hits	133
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

GAK4_HUMAN
NC score	0.153058 (rank : 162)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	593	Target Neighborhood Hits	415	Shared Neighborhood Hits	104
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

K1543_MOUSE
NC score	0.152573 (rank : 163)	θ value	0.0961366 (rank : 137)
Query Neighborhood Hits	593	Target Neighborhood Hits	497	Shared Neighborhood Hits	130
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

GAK11_HUMAN
NC score	0.152550 (rank : 164)	θ value	0.00175202 (rank : 49)
Query Neighborhood Hits	593	Target Neighborhood Hits	409	Shared Neighborhood Hits	104
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

EFS_HUMAN
NC score	0.152462 (rank : 165)	θ value	0.00869519 (rank : 77)
Query Neighborhood Hits	593	Target Neighborhood Hits	348	Shared Neighborhood Hits	102
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

PI5PA_MOUSE
NC score	0.152441 (rank : 166)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	593	Target Neighborhood Hits	331	Shared Neighborhood Hits	159
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRPC_HUMAN
NC score	0.152340 (rank : 167)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	593	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

GAK2_HUMAN
NC score	0.151678 (rank : 168)	θ value	0.00134147 (rank : 47)
Query Neighborhood Hits	593	Target Neighborhood Hits	406	Shared Neighborhood Hits	100
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TGON2_HUMAN
NC score	0.151126 (rank : 169)	θ value	0.00509761 (rank : 69)
Query Neighborhood Hits	593	Target Neighborhood Hits	1037	Shared Neighborhood Hits	167
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CABIN_HUMAN
NC score	0.150542 (rank : 170)	θ value	0.62314 (rank : 220)
Query Neighborhood Hits	593	Target Neighborhood Hits	490	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ALEX_MOUSE
NC score	0.150255 (rank : 171)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	101
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

WASP_MOUSE
NC score	0.149885 (rank : 172)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	593	Target Neighborhood Hits	223	Shared Neighborhood Hits	126
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

BCAR1_HUMAN
NC score	0.149128 (rank : 173)	θ value	0.00509761 (rank : 62)
Query Neighborhood Hits	593	Target Neighborhood Hits	554	Shared Neighborhood Hits	142
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

AUTS2_HUMAN
NC score	0.148857 (rank : 174)	θ value	8.99809 (rank : 543)
Query Neighborhood Hits	593	Target Neighborhood Hits	342	Shared Neighborhood Hits	143
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

TCOF_HUMAN
NC score	0.148830 (rank : 175)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	593	Target Neighborhood Hits	543	Shared Neighborhood Hits	109
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

GAK12_HUMAN
NC score	0.148622 (rank : 176)	θ value	0.00175202 (rank : 50)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	93
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

WASP_HUMAN
NC score	0.148415 (rank : 177)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	117
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

GAK6_HUMAN
NC score	0.148145 (rank : 178)	θ value	0.00175202 (rank : 53)
Query Neighborhood Hits	593	Target Neighborhood Hits	392	Shared Neighborhood Hits	101
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PCQAP_MOUSE
NC score	0.147580 (rank : 179)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	593	Target Neighborhood Hits	506	Shared Neighborhood Hits	158
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

3BP1_HUMAN
NC score	0.147369 (rank : 180)	θ value	8.99809 (rank : 540)
Query Neighborhood Hits	593	Target Neighborhood Hits	376	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RTP3_MOUSE
NC score	0.146997 (rank : 181)	θ value	0.0113563 (rank : 86)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	116
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

CRSP2_HUMAN
NC score	0.146827 (rank : 182)	θ value	0.0148317 (rank : 89)
Query Neighborhood Hits	593	Target Neighborhood Hits	380	Shared Neighborhood Hits	105
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

NUMBL_HUMAN
NC score	0.146565 (rank : 183)	θ value	8.40245e-06 (rank : 25)
Query Neighborhood Hits	593	Target Neighborhood Hits	394	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

GRIN1_MOUSE
NC score	0.146411 (rank : 184)	θ value	6.88961 (rank : 506)
Query Neighborhood Hits	593	Target Neighborhood Hits	337	Shared Neighborhood Hits	115
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K1543_HUMAN
NC score	0.146258 (rank : 185)	θ value	1.38821 (rank : 290)
Query Neighborhood Hits	593	Target Neighborhood Hits	435	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SGIP1_HUMAN
NC score	0.146127 (rank : 186)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	593	Target Neighborhood Hits	198	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ATX2L_HUMAN
NC score	0.145819 (rank : 187)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	593	Target Neighborhood Hits	443	Shared Neighborhood Hits	152
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

FMN1B_MOUSE
NC score	0.145693 (rank : 188)	θ value	5.27518 (rank : 447)
Query Neighborhood Hits	593	Target Neighborhood Hits	447	Shared Neighborhood Hits	176
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

SGIP1_MOUSE
NC score	0.145452 (rank : 189)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ATX2_HUMAN
NC score	0.143907 (rank : 190)	θ value	3.0926 (rank : 374)
Query Neighborhood Hits	593	Target Neighborhood Hits	375	Shared Neighborhood Hits	144
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CEL_HUMAN
NC score	0.143880 (rank : 191)	θ value	1.29631e-06 (rank : 20)
Query Neighborhood Hits	593	Target Neighborhood Hits	896	Shared Neighborhood Hits	178
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

AFF1_HUMAN
NC score	0.143138 (rank : 192)	θ value	1.81305 (rank : 308)
Query Neighborhood Hits	593	Target Neighborhood Hits	506	Shared Neighborhood Hits	128
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ATX2_MOUSE
NC score	0.143033 (rank : 193)	θ value	1.38821 (rank : 275)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	150
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SPR1B_MOUSE
NC score	0.143010 (rank : 194)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	593	Target Neighborhood Hits	395	Shared Neighborhood Hits	94
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SC24A_MOUSE
NC score	0.142986 (rank : 195)	θ value	0.0961366 (rank : 141)
Query Neighborhood Hits	593	Target Neighborhood Hits	394	Shared Neighborhood Hits	129
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

TARA_HUMAN
NC score	0.142872 (rank : 196)	θ value	2.36792 (rank : 367)
Query Neighborhood Hits	593	Target Neighborhood Hits	1626	Shared Neighborhood Hits	244
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CNOT3_HUMAN
NC score	0.142160 (rank : 197)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	593	Target Neighborhood Hits	425	Shared Neighborhood Hits	115
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SF01_MOUSE
NC score	0.142028 (rank : 198)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	116
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SPRR3_HUMAN
NC score	0.141453 (rank : 199)	θ value	0.0736092 (rank : 130)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

K0310_HUMAN
NC score	0.141267 (rank : 200)	θ value	8.99809 (rank : 566)
Query Neighborhood Hits	593	Target Neighborhood Hits	420	Shared Neighborhood Hits	137
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

TROAP_HUMAN
NC score	0.141201 (rank : 201)	θ value	3.0926 (rank : 398)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	97
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

BAG3_HUMAN
NC score	0.141115 (rank : 202)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	112
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

NCOR2_HUMAN
NC score	0.140938 (rank : 203)	θ value	5.27518 (rank : 457)
Query Neighborhood Hits	593	Target Neighborhood Hits	870	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RIN3_HUMAN
NC score	0.140385 (rank : 204)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

BCAR1_MOUSE
NC score	0.139300 (rank : 205)	θ value	0.0563607 (rank : 121)
Query Neighborhood Hits	593	Target Neighborhood Hits	438	Shared Neighborhood Hits	131
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

TM108_HUMAN
NC score	0.139176 (rank : 206)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	593	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

FMN1A_MOUSE
NC score	0.138940 (rank : 207)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	593	Target Neighborhood Hits	423	Shared Neighborhood Hits	172
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

WASF3_HUMAN
NC score	0.138707 (rank : 208)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

NELFA_MOUSE
NC score	0.137566 (rank : 209)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

SPRR3_MOUSE
NC score	0.137370 (rank : 210)	θ value	1.38821 (rank : 301)
Query Neighborhood Hits	593	Target Neighborhood Hits	106	Shared Neighborhood Hits	38
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

PRP5_HUMAN
NC score	0.137102 (rank : 211)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	593	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

SAPS1_HUMAN
NC score	0.136611 (rank : 212)	θ value	0.0113563 (rank : 87)
Query Neighborhood Hits	593	Target Neighborhood Hits	704	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

GAK10_HUMAN
NC score	0.136428 (rank : 213)	θ value	0.0431538 (rank : 113)
Query Neighborhood Hits	593	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
NC score	0.136421 (rank : 214)	θ value	0.0431538 (rank : 114)
Query Neighborhood Hits	593	Target Neighborhood Hits	268	Shared Neighborhood Hits	71
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LR37A_HUMAN
NC score	0.135618 (rank : 215)	θ value	0.00175202 (rank : 54)
Query Neighborhood Hits	593	Target Neighborhood Hits	720	Shared Neighborhood Hits	157
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LAD1_HUMAN
NC score	0.135466 (rank : 216)	θ value	0.0252991 (rank : 98)
Query Neighborhood Hits	593	Target Neighborhood Hits	441	Shared Neighborhood Hits	90
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MILK1_HUMAN
NC score	0.135416 (rank : 217)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	593	Target Neighborhood Hits	427	Shared Neighborhood Hits	149
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MARCS_MOUSE
NC score	0.135321 (rank : 218)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	66
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PRR13_MOUSE
NC score	0.134790 (rank : 219)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	593	Target Neighborhood Hits	54	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CS007_HUMAN
NC score	0.134550 (rank : 220)	θ value	8.99809 (rank : 548)
Query Neighborhood Hits	593	Target Neighborhood Hits	401	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

TP53B_MOUSE
NC score	0.132890 (rank : 221)	θ value	0.0431538 (rank : 120)
Query Neighborhood Hits	593	Target Neighborhood Hits	644	Shared Neighborhood Hits	125
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AP180_MOUSE
NC score	0.132820 (rank : 222)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	71
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

NUP53_HUMAN
NC score	0.132369 (rank : 223)	θ value	0.000602161 (rank : 40)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

RBM12_MOUSE
NC score	0.132189 (rank : 224)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	593	Target Neighborhood Hits	313	Shared Neighborhood Hits	124
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

GAB1_MOUSE
NC score	0.131895 (rank : 225)	θ value	0.00869519 (rank : 79)
Query Neighborhood Hits	593	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_HUMAN
NC score	0.131673 (rank : 226)	θ value	0.00228821 (rank : 57)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	87
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SPR1A_MOUSE
NC score	0.130392 (rank : 227)	θ value	0.00869519 (rank : 81)
Query Neighborhood Hits	593	Target Neighborhood Hits	343	Shared Neighborhood Hits	82
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

GA2L2_MOUSE
NC score	0.129974 (rank : 228)	θ value	0.00665767 (rank : 70)
Query Neighborhood Hits	593	Target Neighborhood Hits	395	Shared Neighborhood Hits	116
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

NFRKB_HUMAN
NC score	0.129697 (rank : 229)	θ value	0.813845 (rank : 247)
Query Neighborhood Hits	593	Target Neighborhood Hits	211	Shared Neighborhood Hits	65
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

CSKI1_HUMAN
NC score	0.129545 (rank : 230)	θ value	1.38821 (rank : 281)
Query Neighborhood Hits	593	Target Neighborhood Hits	997	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LPP_HUMAN
NC score	0.128760 (rank : 231)	θ value	0.000121331 (rank : 33)
Query Neighborhood Hits	593	Target Neighborhood Hits	775	Shared Neighborhood Hits	164
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MUC13_MOUSE
NC score	0.128513 (rank : 232)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	593	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

WASF3_MOUSE
NC score	0.126967 (rank : 233)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

DIAP1_HUMAN
NC score	0.126585 (rank : 234)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	593	Target Neighborhood Hits	784	Shared Neighborhood Hits	182
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ARI1B_HUMAN
NC score	0.126527 (rank : 235)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	593	Target Neighborhood Hits	567	Shared Neighborhood Hits	163
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CG1_HUMAN
NC score	0.126472 (rank : 236)	θ value	0.813845 (rank : 232)
Query Neighborhood Hits	593	Target Neighborhood Hits	222	Shared Neighborhood Hits	82
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

EFS_MOUSE
NC score	0.126412 (rank : 237)	θ value	1.38821 (rank : 284)
Query Neighborhood Hits	593	Target Neighborhood Hits	389	Shared Neighborhood Hits	98
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

TCGAP_HUMAN
NC score	0.126214 (rank : 238)	θ value	0.00509761 (rank : 68)
Query Neighborhood Hits	593	Target Neighborhood Hits	872	Shared Neighborhood Hits	179
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CIZ1_HUMAN
NC score	0.125924 (rank : 239)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	593	Target Neighborhood Hits	359	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SYP2L_HUMAN
NC score	0.125321 (rank : 240)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	593	Target Neighborhood Hits	400	Shared Neighborhood Hits	139
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

NUP53_MOUSE
NC score	0.125060 (rank : 241)	θ value	0.00035302 (rank : 37)
Query Neighborhood Hits	593	Target Neighborhood Hits	94	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

SNPC4_HUMAN
NC score	0.124949 (rank : 242)	θ value	1.06291 (rank : 268)
Query Neighborhood Hits	593	Target Neighborhood Hits	589	Shared Neighborhood Hits	137
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

GAK7_HUMAN
NC score	0.124563 (rank : 243)	θ value	0.125558 (rank : 148)
Query Neighborhood Hits	593	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

HRX_HUMAN
NC score	0.124485 (rank : 244)	θ value	2.36792 (rank : 351)
Query Neighborhood Hits	593	Target Neighborhood Hits	825	Shared Neighborhood Hits	180
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ENL_HUMAN
NC score	0.124426 (rank : 245)	θ value	8.99809 (rank : 557)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	87
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

GAK8_HUMAN
NC score	0.124181 (rank : 246)	θ value	0.0431538 (rank : 115)
Query Neighborhood Hits	593	Target Neighborhood Hits	145	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK3_HUMAN
NC score	0.122864 (rank : 247)	θ value	0.813845 (rank : 238)
Query Neighborhood Hits	593	Target Neighborhood Hits	182	Shared Neighborhood Hits	42
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NELFA_HUMAN
NC score	0.122410 (rank : 248)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	593	Target Neighborhood Hits	161	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NFRKB_MOUSE
NC score	0.122372 (rank : 249)	θ value	5.27518 (rank : 460)
Query Neighborhood Hits	593	Target Neighborhood Hits	393	Shared Neighborhood Hits	120
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PS1C2_HUMAN
NC score	0.122260 (rank : 250)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	593	Target Neighborhood Hits	66	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

IF35_MOUSE
NC score	0.121843 (rank : 251)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	593	Target Neighborhood Hits	210	Shared Neighborhood Hits	109
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

GAK18_HUMAN
NC score	0.121216 (rank : 252)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	593	Target Neighborhood Hits	116	Shared Neighborhood Hits	44
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ZN645_HUMAN
NC score	0.121210 (rank : 253)	θ value	0.0193708 (rank : 97)
Query Neighborhood Hits	593	Target Neighborhood Hits	265	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

CSKI1_MOUSE
NC score	0.121148 (rank : 254)	θ value	1.38821 (rank : 282)
Query Neighborhood Hits	593	Target Neighborhood Hits	1031	Shared Neighborhood Hits	257
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

AP180_HUMAN
NC score	0.120955 (rank : 255)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	593	Target Neighborhood Hits	183	Shared Neighborhood Hits	81
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

SPT5H_MOUSE
NC score	0.120906 (rank : 256)	θ value	0.365318 (rank : 205)
Query Neighborhood Hits	593	Target Neighborhood Hits	437	Shared Neighborhood Hits	122
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

CI079_HUMAN
NC score	0.120795 (rank : 257)	θ value	0.279714 (rank : 174)
Query Neighborhood Hits	593	Target Neighborhood Hits	288	Shared Neighborhood Hits	91
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

AFF1_MOUSE
NC score	0.120352 (rank : 258)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	593	Target Neighborhood Hits	351	Shared Neighborhood Hits	112
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MUC5B_HUMAN
NC score	0.120298 (rank : 259)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	593	Target Neighborhood Hits	1020	Shared Neighborhood Hits	181
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

DIAP1_MOUSE
NC score	0.119351 (rank : 260)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	593	Target Neighborhood Hits	839	Shared Neighborhood Hits	166
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

SPT5H_HUMAN
NC score	0.119247 (rank : 261)	θ value	0.365318 (rank : 204)
Query Neighborhood Hits	593	Target Neighborhood Hits	436	Shared Neighborhood Hits	121
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

PDC6I_HUMAN
NC score	0.118876 (rank : 262)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	132
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

TMAP1_HUMAN
NC score	0.118552 (rank : 263)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	593	Target Neighborhood Hits	140	Shared Neighborhood Hits	52
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

KI67_HUMAN
NC score	0.118296 (rank : 264)	θ value	1.81305 (rank : 320)
Query Neighborhood Hits	593	Target Neighborhood Hits	581	Shared Neighborhood Hits	94
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MAP1A_HUMAN
NC score	0.118217 (rank : 265)	θ value	0.813845 (rank : 245)
Query Neighborhood Hits	593	Target Neighborhood Hits	1626	Shared Neighborhood Hits	223
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CD248_HUMAN
NC score	0.118168 (rank : 266)	θ value	8.40245e-06 (rank : 24)
Query Neighborhood Hits	593	Target Neighborhood Hits	679	Shared Neighborhood Hits	147
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SC24D_HUMAN
NC score	0.117750 (rank : 267)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	95
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SELPL_HUMAN
NC score	0.117034 (rank : 268)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	593	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

ASPP1_MOUSE
NC score	0.117018 (rank : 269)	θ value	0.0193708 (rank : 91)
Query Neighborhood Hits	593	Target Neighborhood Hits	1244	Shared Neighborhood Hits	196
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PTN23_HUMAN
NC score	0.116827 (rank : 270)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	593	Target Neighborhood Hits	646	Shared Neighborhood Hits	207
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

ZIM10_HUMAN
NC score	0.116140 (rank : 271)	θ value	0.0563607 (rank : 125)
Query Neighborhood Hits	593	Target Neighborhood Hits	577	Shared Neighborhood Hits	143
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZYX_HUMAN
NC score	0.116024 (rank : 272)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	593	Target Neighborhood Hits	387	Shared Neighborhood Hits	130
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

DOT1L_HUMAN
NC score	0.116008 (rank : 273)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	593	Target Neighborhood Hits	660	Shared Neighborhood Hits	138
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SHAN1_HUMAN
NC score	0.115924 (rank : 274)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	593	Target Neighborhood Hits	1041	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PSL1_HUMAN
NC score	0.115862 (rank : 275)	θ value	0.0252991 (rank : 100)
Query Neighborhood Hits	593	Target Neighborhood Hits	650	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CNOT3_MOUSE
NC score	0.115800 (rank : 276)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	593	Target Neighborhood Hits	504	Shared Neighborhood Hits	111
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

VCX3_HUMAN
NC score	0.115273 (rank : 277)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	593	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

RTN4_MOUSE
NC score	0.114933 (rank : 278)	θ value	0.365318 (rank : 202)
Query Neighborhood Hits	593	Target Neighborhood Hits	341	Shared Neighborhood Hits	101
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

IASPP_MOUSE
NC score	0.114536 (rank : 279)	θ value	6.88961 (rank : 508)
Query Neighborhood Hits	593	Target Neighborhood Hits	1024	Shared Neighborhood Hits	192
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PHC1_HUMAN
NC score	0.114178 (rank : 280)	θ value	1.81305 (rank : 330)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

NUMBL_MOUSE
NC score	0.114165 (rank : 281)	θ value	0.00665767 (rank : 72)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	42
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

PRCC_HUMAN
NC score	0.113901 (rank : 282)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	593	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

RTN4_HUMAN
NC score	0.113786 (rank : 283)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	593	Target Neighborhood Hits	357	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CASC3_MOUSE
NC score	0.113709 (rank : 284)	θ value	0.365318 (rank : 189)
Query Neighborhood Hits	593	Target Neighborhood Hits	333	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

IASPP_HUMAN
NC score	0.113187 (rank : 285)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	593	Target Neighborhood Hits	688	Shared Neighborhood Hits	158
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SF3A1_HUMAN
NC score	0.113028 (rank : 286)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	103
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

NCOR2_MOUSE
NC score	0.112664 (rank : 287)	θ value	5.27518 (rank : 458)
Query Neighborhood Hits	593	Target Neighborhood Hits	790	Shared Neighborhood Hits	151
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PRR8_HUMAN
NC score	0.112575 (rank : 288)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	593	Target Neighborhood Hits	217	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

ATX2L_MOUSE
NC score	0.112503 (rank : 289)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	593	Target Neighborhood Hits	401	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

RNC_HUMAN
NC score	0.112366 (rank : 290)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	593	Target Neighborhood Hits	176	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

BLNK_MOUSE
NC score	0.112308 (rank : 291)	θ value	0.365318 (rank : 188)
Query Neighborhood Hits	593	Target Neighborhood Hits	296	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CSF1_HUMAN
NC score	0.112136 (rank : 292)	θ value	0.0113563 (rank : 84)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	75
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

PTN23_MOUSE
NC score	0.112067 (rank : 293)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	593	Target Neighborhood Hits	726	Shared Neighborhood Hits	232
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

LAD1_MOUSE
NC score	0.111346 (rank : 294)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	593	Target Neighborhood Hits	391	Shared Neighborhood Hits	91
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

GRIN1_HUMAN
NC score	0.111057 (rank : 295)	θ value	2.36792 (rank : 349)
Query Neighborhood Hits	593	Target Neighborhood Hits	681	Shared Neighborhood Hits	135
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SRBP1_MOUSE
NC score	0.110277 (rank : 296)	θ value	0.0961366 (rank : 143)
Query Neighborhood Hits	593	Target Neighborhood Hits	384	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PDC6I_MOUSE
NC score	0.110167 (rank : 297)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	593	Target Neighborhood Hits	275	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

RP1L1_HUMAN
NC score	0.110025 (rank : 298)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	593	Target Neighborhood Hits	1072	Shared Neighborhood Hits	167
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ZYX_MOUSE
NC score	0.109876 (rank : 299)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	593	Target Neighborhood Hits	347	Shared Neighborhood Hits	110
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

PHC1_MOUSE
NC score	0.109653 (rank : 300)	θ value	0.365318 (rank : 198)
Query Neighborhood Hits	593	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

PRRT1_MOUSE
NC score	0.109524 (rank : 301)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

TARA_MOUSE
NC score	0.109394 (rank : 302)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	593	Target Neighborhood Hits	1133	Shared Neighborhood Hits	171
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZIMP7_MOUSE
NC score	0.109261 (rank : 303)	θ value	0.21417 (rank : 173)
Query Neighborhood Hits	593	Target Neighborhood Hits	566	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PS1C2_MOUSE
NC score	0.108884 (rank : 304)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	593	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

VCXC_HUMAN
NC score	0.108509 (rank : 305)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	593	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

SMOO_HUMAN
NC score	0.108452 (rank : 306)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	593	Target Neighborhood Hits	391	Shared Neighborhood Hits	128
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CK024_MOUSE
NC score	0.108195 (rank : 307)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

SSBP4_HUMAN
NC score	0.108177 (rank : 308)	θ value	0.00665767 (rank : 75)
Query Neighborhood Hits	593	Target Neighborhood Hits	753	Shared Neighborhood Hits	149
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SF3B1_HUMAN
NC score	0.107995 (rank : 309)	θ value	0.163984 (rank : 160)
Query Neighborhood Hits	593	Target Neighborhood Hits	341	Shared Neighborhood Hits	76
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

JPH2_HUMAN
NC score	0.107961 (rank : 310)	θ value	0.000602161 (rank : 39)
Query Neighborhood Hits	593	Target Neighborhood Hits	639	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SF3B1_MOUSE
NC score	0.107843 (rank : 311)	θ value	0.163984 (rank : 161)
Query Neighborhood Hits	593	Target Neighborhood Hits	352	Shared Neighborhood Hits	77
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

OGFR_MOUSE
NC score	0.107673 (rank : 312)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	593	Target Neighborhood Hits	584	Shared Neighborhood Hits	101
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TB182_HUMAN
NC score	0.107629 (rank : 313)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	593	Target Neighborhood Hits	414	Shared Neighborhood Hits	104
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

PHC3_MOUSE
NC score	0.107628 (rank : 314)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

FMNL_MOUSE
NC score	0.107568 (rank : 315)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	593	Target Neighborhood Hits	428	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

CRTC1_MOUSE
NC score	0.107457 (rank : 316)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	593	Target Neighborhood Hits	230	Shared Neighborhood Hits	81
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

IF4G1_HUMAN
NC score	0.107342 (rank : 317)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	593	Target Neighborhood Hits	347	Shared Neighborhood Hits	127
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

CD2_HUMAN
NC score	0.107005 (rank : 318)	θ value	0.813845 (rank : 231)
Query Neighborhood Hits	593	Target Neighborhood Hits	504	Shared Neighborhood Hits	110
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

RBM12_HUMAN
NC score	0.106659 (rank : 319)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	593	Target Neighborhood Hits	298	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

MAVS_HUMAN
NC score	0.106647 (rank : 320)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	593	Target Neighborhood Hits	271	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

SF3A1_MOUSE
NC score	0.106386 (rank : 321)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	593	Target Neighborhood Hits	198	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

ERRFI_MOUSE
NC score	0.106168 (rank : 322)	θ value	0.00509761 (rank : 65)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

SPR2H_MOUSE
NC score	0.105668 (rank : 323)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	593	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SDC3_MOUSE
NC score	0.105336 (rank : 324)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	593	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

LDB3_HUMAN
NC score	0.104731 (rank : 325)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	593	Target Neighborhood Hits	497	Shared Neighborhood Hits	155
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PRAX_HUMAN
NC score	0.104619 (rank : 326)	θ value	1.81305 (rank : 331)
Query Neighborhood Hits	593	Target Neighborhood Hits	215	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

VCX1_HUMAN
NC score	0.104206 (rank : 327)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	593	Target Neighborhood Hits	129	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

SMRC2_MOUSE
NC score	0.104163 (rank : 328)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	593	Target Neighborhood Hits	487	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PHC2_MOUSE
NC score	0.104106 (rank : 329)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	593	Target Neighborhood Hits	156	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

IF4G1_MOUSE
NC score	0.103667 (rank : 330)	θ value	3.0926 (rank : 381)
Query Neighborhood Hits	593	Target Neighborhood Hits	534	Shared Neighborhood Hits	135
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MUCDL_MOUSE
NC score	0.103346 (rank : 331)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	593	Target Neighborhood Hits	461	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

IRS2_HUMAN
NC score	0.103188 (rank : 332)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	593	Target Neighborhood Hits	262	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

RFX1_HUMAN
NC score	0.103060 (rank : 333)	θ value	8.99809 (rank : 582)
Query Neighborhood Hits	593	Target Neighborhood Hits	256	Shared Neighborhood Hits	127
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

MBB1A_HUMAN
NC score	0.102717 (rank : 334)	θ value	3.0926 (rank : 383)
Query Neighborhood Hits	593	Target Neighborhood Hits	665	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ENAH_HUMAN
NC score	0.102674 (rank : 335)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	593	Target Neighborhood Hits	784	Shared Neighborhood Hits	163
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PPRB_MOUSE
NC score	0.102493 (rank : 336)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	593	Target Neighborhood Hits	354	Shared Neighborhood Hits	99
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RU1C_MOUSE
NC score	0.102236 (rank : 337)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	593	Target Neighborhood Hits	83	Shared Neighborhood Hits	49
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SRBP1_HUMAN
NC score	0.101865 (rank : 338)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SYP2L_MOUSE
NC score	0.101804 (rank : 339)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	593	Target Neighborhood Hits	289	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ZN750_MOUSE
NC score	0.101766 (rank : 340)	θ value	1.81305 (rank : 337)
Query Neighborhood Hits	593	Target Neighborhood Hits	346	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

GAK17_HUMAN
NC score	0.101762 (rank : 341)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	593	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK9_HUMAN
NC score	0.101647 (rank : 342)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	593	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

CT032_HUMAN
NC score	0.101172 (rank : 343)	θ value	0.00509761 (rank : 64)
Query Neighborhood Hits	593	Target Neighborhood Hits	235	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

GAK15_HUMAN
NC score	0.101157 (rank : 344)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	593	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P62688	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(I) Gag protein).

CSKI2_HUMAN
NC score	0.101027 (rank : 345)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	593	Target Neighborhood Hits	747	Shared Neighborhood Hits	194
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DIDO1_HUMAN
NC score	0.101018 (rank : 346)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	593	Target Neighborhood Hits	960	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SDC3_HUMAN
NC score	0.101003 (rank : 347)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	593	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

RU1C_HUMAN
NC score	0.100918 (rank : 348)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	593	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

AMELX_HUMAN
NC score	0.100346 (rank : 349)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	593	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

TAB3_MOUSE
NC score	0.100026 (rank : 350)	θ value	1.06291 (rank : 269)
Query Neighborhood Hits	593	Target Neighborhood Hits	273	Shared Neighborhood Hits	97
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

ZN598_HUMAN
NC score	0.099864 (rank : 351)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	593	Target Neighborhood Hits	339	Shared Neighborhood Hits	87
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

PHC3_HUMAN
NC score	0.099821 (rank : 352)	θ value	1.38821 (rank : 298)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PDCD7_HUMAN
NC score	0.099693 (rank : 353)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	593	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

TCRG1_MOUSE
NC score	0.099687 (rank : 354)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	593	Target Neighborhood Hits	947	Shared Neighborhood Hits	168
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RTKN_HUMAN
NC score	0.099491 (rank : 355)	θ value	0.00509761 (rank : 66)
Query Neighborhood Hits	593	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

CEND_HUMAN
NC score	0.099421 (rank : 356)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	593	Target Neighborhood Hits	84	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

SEPT9_HUMAN
NC score	0.099391 (rank : 357)	θ value	0.00298849 (rank : 60)
Query Neighborhood Hits	593	Target Neighborhood Hits	706	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CT151_HUMAN
NC score	0.099183 (rank : 358)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	593	Target Neighborhood Hits	382	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

GTSE1_HUMAN
NC score	0.099084 (rank : 359)	θ value	6.88961 (rank : 507)
Query Neighborhood Hits	593	Target Neighborhood Hits	193	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

PER1_HUMAN
NC score	0.098910 (rank : 360)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	593	Target Neighborhood Hits	215	Shared Neighborhood Hits	102
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

MKL1_MOUSE
NC score	0.098906 (rank : 361)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	593	Target Neighborhood Hits	667	Shared Neighborhood Hits	148
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

ATX7_HUMAN
NC score	0.098827 (rank : 362)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	593	Target Neighborhood Hits	351	Shared Neighborhood Hits	94
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

3BP2_HUMAN
NC score	0.098712 (rank : 363)	θ value	3.0926 (rank : 370)
Query Neighborhood Hits	593	Target Neighborhood Hits	296	Shared Neighborhood Hits	92
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

GNAS1_MOUSE
NC score	0.098701 (rank : 364)	θ value	0.00298849 (rank : 58)
Query Neighborhood Hits	593	Target Neighborhood Hits	651	Shared Neighborhood Hits	147
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SMRC2_HUMAN
NC score	0.098643 (rank : 365)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	593	Target Neighborhood Hits	499	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

GAK19_HUMAN
NC score	0.098635 (rank : 366)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	593	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

NEUM_HUMAN
NC score	0.098606 (rank : 367)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

MAP1B_HUMAN
NC score	0.098593 (rank : 368)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	593	Target Neighborhood Hits	903	Shared Neighborhood Hits	117
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

ZAN_HUMAN
NC score	0.098197 (rank : 369)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	593	Target Neighborhood Hits	679	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

PHLB1_HUMAN
NC score	0.097890 (rank : 370)	θ value	0.47712 (rank : 213)
Query Neighborhood Hits	593	Target Neighborhood Hits	1038	Shared Neighborhood Hits	166
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRRT1_HUMAN
NC score	0.097461 (rank : 371)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	593	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

CO002_HUMAN
NC score	0.097425 (rank : 372)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	593	Target Neighborhood Hits	387	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

ATX7_MOUSE
NC score	0.097234 (rank : 373)	θ value	0.62314 (rank : 217)
Query Neighborhood Hits	593	Target Neighborhood Hits	328	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

NPAS4_MOUSE
NC score	0.097194 (rank : 374)	θ value	0.279714 (rank : 179)
Query Neighborhood Hits	593	Target Neighborhood Hits	245	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NFH_HUMAN
NC score	0.097092 (rank : 375)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	593	Target Neighborhood Hits	1242	Shared Neighborhood Hits	166
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

JPH2_MOUSE
NC score	0.096989 (rank : 376)	θ value	3.0926 (rank : 382)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

EP400_HUMAN
NC score	0.096615 (rank : 377)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	593	Target Neighborhood Hits	556	Shared Neighborhood Hits	180
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

MN1_HUMAN
NC score	0.096447 (rank : 378)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	593	Target Neighborhood Hits	196	Shared Neighborhood Hits	69
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

BPTF_HUMAN
NC score	0.096301 (rank : 379)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	593	Target Neighborhood Hits	786	Shared Neighborhood Hits	135
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PDZD2_HUMAN
NC score	0.096155 (rank : 380)	θ value	0.0563607 (rank : 122)
Query Neighborhood Hits	593	Target Neighborhood Hits	772	Shared Neighborhood Hits	148
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SYNPO_HUMAN
NC score	0.095545 (rank : 381)	θ value	5.27518 (rank : 471)
Query Neighborhood Hits	593	Target Neighborhood Hits	281	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

LDB3_MOUSE
NC score	0.095452 (rank : 382)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	593	Target Neighborhood Hits	510	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

IWS1_MOUSE
NC score	0.095324 (rank : 383)	θ value	5.27518 (rank : 452)
Query Neighborhood Hits	593	Target Neighborhood Hits	1258	Shared Neighborhood Hits	166
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IQEC2_MOUSE
NC score	0.095254 (rank : 384)	θ value	0.21417 (rank : 170)
Query Neighborhood Hits	593	Target Neighborhood Hits	417	Shared Neighborhood Hits	137
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

3BP1_MOUSE
NC score	0.095121 (rank : 385)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	593	Target Neighborhood Hits	238	Shared Neighborhood Hits	102
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CD248_MOUSE
NC score	0.095051 (rank : 386)	θ value	0.0193708 (rank : 93)
Query Neighborhood Hits	593	Target Neighborhood Hits	578	Shared Neighborhood Hits	107
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

APC_HUMAN
NC score	0.095031 (rank : 387)	θ value	0.365318 (rank : 186)
Query Neighborhood Hits	593	Target Neighborhood Hits	603	Shared Neighborhood Hits	105
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PRAX_MOUSE
NC score	0.094944 (rank : 388)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	61
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

CECR2_HUMAN
NC score	0.094765 (rank : 389)	θ value	0.62314 (rank : 221)
Query Neighborhood Hits	593	Target Neighborhood Hits	543	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BAZ2A_MOUSE
NC score	0.094746 (rank : 390)	θ value	5.27518 (rank : 435)
Query Neighborhood Hits	593	Target Neighborhood Hits	744	Shared Neighborhood Hits	156
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

VASP_HUMAN
NC score	0.094717 (rank : 391)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	93
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPTA3_MOUSE
NC score	0.094612 (rank : 392)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	593	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

PARM1_MOUSE
NC score	0.094277 (rank : 393)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	593	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

ASPP1_HUMAN
NC score	0.094271 (rank : 394)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	593	Target Neighborhood Hits	956	Shared Neighborhood Hits	138
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TCRG1_HUMAN
NC score	0.094157 (rank : 395)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	593	Target Neighborhood Hits	929	Shared Neighborhood Hits	159
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

NPBL_MOUSE
NC score	0.094056 (rank : 396)	θ value	0.47712 (rank : 212)
Query Neighborhood Hits	593	Target Neighborhood Hits	1041	Shared Neighborhood Hits	133
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.093888 (rank : 397)	θ value	1.38821 (rank : 296)
Query Neighborhood Hits	593	Target Neighborhood Hits	1311	Shared Neighborhood Hits	152
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CASC3_HUMAN
NC score	0.093856 (rank : 398)	θ value	2.36792 (rank : 342)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

GAK14_HUMAN
NC score	0.093833 (rank : 399)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	593	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P62687	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_16p3.3 provirus ancestral Gag polyprotein (Gag polyprotein).

FYB_HUMAN
NC score	0.093809 (rank : 400)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	593	Target Neighborhood Hits	379	Shared Neighborhood Hits	102
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

PYGO2_HUMAN
NC score	0.093752 (rank : 401)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

SH22A_HUMAN
NC score	0.093697 (rank : 402)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

TAF3_HUMAN
NC score	0.093252 (rank : 403)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	593	Target Neighborhood Hits	568	Shared Neighborhood Hits	106
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

IWS1_HUMAN
NC score	0.093078 (rank : 404)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	593	Target Neighborhood Hits	1241	Shared Neighborhood Hits	156
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SFRIP_HUMAN
NC score	0.092605 (rank : 405)	θ value	0.813845 (rank : 252)
Query Neighborhood Hits	593	Target Neighborhood Hits	530	Shared Neighborhood Hits	86
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

MYST3_HUMAN
NC score	0.092193 (rank : 406)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	593	Target Neighborhood Hits	772	Shared Neighborhood Hits	161
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

EPN1_HUMAN
NC score	0.092049 (rank : 407)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	593	Target Neighborhood Hits	206	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

NEUM_MOUSE
NC score	0.092020 (rank : 408)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	593	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

SH22A_MOUSE
NC score	0.091341 (rank : 409)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	593	Target Neighborhood Hits	179	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

ANK2_HUMAN
NC score	0.091300 (rank : 410)	θ value	0.00390308 (rank : 61)
Query Neighborhood Hits	593	Target Neighborhood Hits	1615	Shared Neighborhood Hits	233
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

K0460_HUMAN
NC score	0.091270 (rank : 411)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	593	Target Neighborhood Hits	357	Shared Neighborhood Hits	102
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

PAF49_HUMAN
NC score	0.091088 (rank : 412)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	593	Target Neighborhood Hits	169	Shared Neighborhood Hits	61
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

GAK13_HUMAN
NC score	0.090718 (rank : 413)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	593	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	P62686	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Gag polyprotein (Gag polyprotein).

EP400_MOUSE
NC score	0.090494 (rank : 414)	θ value	5.27518 (rank : 444)
Query Neighborhood Hits	593	Target Neighborhood Hits	592	Shared Neighborhood Hits	177
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

WBS14_MOUSE
NC score	0.090462 (rank : 415)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	593	Target Neighborhood Hits	171	Shared Neighborhood Hits	85
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZIM10_MOUSE
NC score	0.089881 (rank : 416)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	593	Target Neighborhood Hits	430	Shared Neighborhood Hits	105
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

JADE2_MOUSE
NC score	0.089831 (rank : 417)	θ value	0.00665767 (rank : 71)
Query Neighborhood Hits	593	Target Neighborhood Hits	560	Shared Neighborhood Hits	127
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

TULP4_HUMAN
NC score	0.089821 (rank : 418)	θ value	0.0148317 (rank : 90)
Query Neighborhood Hits	593	Target Neighborhood Hits	426	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TAF3_MOUSE
NC score	0.089820 (rank : 419)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	593	Target Neighborhood Hits	463	Shared Neighborhood Hits	86
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

LARP4_MOUSE
NC score	0.089706 (rank : 420)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

ACINU_MOUSE
NC score	0.089551 (rank : 421)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	593	Target Neighborhood Hits	712	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LCP2_MOUSE
NC score	0.089450 (rank : 422)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	593	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ELN_HUMAN
NC score	0.089110 (rank : 423)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

R3HD2_MOUSE
NC score	0.088968 (rank : 424)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	593	Target Neighborhood Hits	397	Shared Neighborhood Hits	112
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CITE4_HUMAN
NC score	0.088880 (rank : 425)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	593	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

IF35_HUMAN
NC score	0.088846 (rank : 426)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	593	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CJ012_HUMAN
NC score	0.088768 (rank : 427)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	593	Target Neighborhood Hits	467	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

TAB3_HUMAN
NC score	0.088579 (rank : 428)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	593	Target Neighborhood Hits	168	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

PHAR2_HUMAN
NC score	0.088569 (rank : 429)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	593	Target Neighborhood Hits	208	Shared Neighborhood Hits	62
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

ARMX2_MOUSE
NC score	0.088513 (rank : 430)	θ value	8.99809 (rank : 542)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	93
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

EPN1_MOUSE
NC score	0.088493 (rank : 431)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	90
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

PHLB1_MOUSE
NC score	0.088436 (rank : 432)	θ value	1.06291 (rank : 265)
Query Neighborhood Hits	593	Target Neighborhood Hits	678	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SYNP2_MOUSE
NC score	0.088436 (rank : 433)	θ value	3.0926 (rank : 392)
Query Neighborhood Hits	593	Target Neighborhood Hits	252	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

RBM16_HUMAN
NC score	0.088352 (rank : 434)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	593	Target Neighborhood Hits	300	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SMR3B_HUMAN
NC score	0.088327 (rank : 435)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	593	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

PER1_MOUSE
NC score	0.088074 (rank : 436)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	593	Target Neighborhood Hits	235	Shared Neighborhood Hits	105
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PO6F2_MOUSE
NC score	0.087785 (rank : 437)	θ value	8.99809 (rank : 577)
Query Neighborhood Hits	593	Target Neighborhood Hits	639	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CTDP1_HUMAN
NC score	0.087663 (rank : 438)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	593	Target Neighborhood Hits	416	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

IL3RB_HUMAN
NC score	0.087639 (rank : 439)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

MYST3_MOUSE
NC score	0.087502 (rank : 440)	θ value	2.36792 (rank : 359)
Query Neighborhood Hits	593	Target Neighborhood Hits	688	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

LIPS_HUMAN
NC score	0.087335 (rank : 441)	θ value	6.88961 (rank : 513)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	95
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

SYN2_HUMAN
NC score	0.087307 (rank : 442)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	109
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

K0460_MOUSE
NC score	0.087238 (rank : 443)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	99
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MAP1B_MOUSE
NC score	0.087137 (rank : 444)	θ value	1.38821 (rank : 292)
Query Neighborhood Hits	593	Target Neighborhood Hits	977	Shared Neighborhood Hits	135
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BORG5_HUMAN
NC score	0.087074 (rank : 445)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	593	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

GA2L3_HUMAN
NC score	0.086454 (rank : 446)	θ value	5.27518 (rank : 448)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

MYO15_HUMAN
NC score	0.086207 (rank : 447)	θ value	0.0431538 (rank : 117)
Query Neighborhood Hits	593	Target Neighborhood Hits	671	Shared Neighborhood Hits	189
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SHAN2_HUMAN
NC score	0.086031 (rank : 448)	θ value	0.0563607 (rank : 123)
Query Neighborhood Hits	593	Target Neighborhood Hits	346	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

MAGC1_HUMAN
NC score	0.085980 (rank : 449)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	593	Target Neighborhood Hits	431	Shared Neighborhood Hits	136
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

CEND1_HUMAN
NC score	0.085777 (rank : 450)	θ value	9.29e-05 (rank : 31)
Query Neighborhood Hits	593	Target Neighborhood Hits	284	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

ERRFI_HUMAN
NC score	0.085612 (rank : 451)	θ value	0.813845 (rank : 237)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

IL3RB_MOUSE
NC score	0.085071 (rank : 452)	θ value	0.0961366 (rank : 136)
Query Neighborhood Hits	593	Target Neighborhood Hits	355	Shared Neighborhood Hits	78
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

CSKI2_MOUSE
NC score	0.084518 (rank : 453)	θ value	8.99809 (rank : 550)
Query Neighborhood Hits	593	Target Neighborhood Hits	812	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

COIA1_HUMAN
NC score	0.084252 (rank : 454)	θ value	2.36792 (rank : 344)
Query Neighborhood Hits	593	Target Neighborhood Hits	447	Shared Neighborhood Hits	118
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PER3_HUMAN
NC score	0.084140 (rank : 455)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	593	Target Neighborhood Hits	479	Shared Neighborhood Hits	121
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PRGC2_HUMAN
NC score	0.084017 (rank : 456)	θ value	0.365318 (rank : 200)
Query Neighborhood Hits	593	Target Neighborhood Hits	272	Shared Neighborhood Hits	62
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

AMOT_HUMAN
NC score	0.083844 (rank : 457)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	593	Target Neighborhood Hits	712	Shared Neighborhood Hits	125
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

RD23B_MOUSE
NC score	0.083824 (rank : 458)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PPRB_HUMAN
NC score	0.083384 (rank : 459)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	593	Target Neighborhood Hits	311	Shared Neighborhood Hits	79
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SETBP_MOUSE
NC score	0.083233 (rank : 460)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	593	Target Neighborhood Hits	352	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CCD1A_HUMAN
NC score	0.083181 (rank : 461)	θ value	3.0926 (rank : 376)
Query Neighborhood Hits	593	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

TENS1_HUMAN
NC score	0.083176 (rank : 462)	θ value	5.27518 (rank : 473)
Query Neighborhood Hits	593	Target Neighborhood Hits	400	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

APC_MOUSE
NC score	0.083016 (rank : 463)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	593	Target Neighborhood Hits	441	Shared Neighborhood Hits	78
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

IL3B2_MOUSE
NC score	0.082812 (rank : 464)	θ value	1.06291 (rank : 264)
Query Neighborhood Hits	593	Target Neighborhood Hits	372	Shared Neighborhood Hits	83
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

MEGF9_MOUSE
NC score	0.082685 (rank : 465)	θ value	0.62314 (rank : 226)
Query Neighborhood Hits	593	Target Neighborhood Hits	896	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

VASP_MOUSE
NC score	0.082671 (rank : 466)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	83
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SF3B4_HUMAN
NC score	0.082458 (rank : 467)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

PDCD7_MOUSE
NC score	0.081986 (rank : 468)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

RANB9_HUMAN
NC score	0.081978 (rank : 469)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	593	Target Neighborhood Hits	179	Shared Neighborhood Hits	79
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

MILK2_HUMAN
NC score	0.081730 (rank : 470)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	593	Target Neighborhood Hits	457	Shared Neighborhood Hits	105
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

PRPE_HUMAN
NC score	0.081486 (rank : 471)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

IQEC2_HUMAN
NC score	0.081360 (rank : 472)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	593	Target Neighborhood Hits	403	Shared Neighborhood Hits	133
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SYNP2_HUMAN
NC score	0.081239 (rank : 473)	θ value	0.47712 (rank : 216)
Query Neighborhood Hits	593	Target Neighborhood Hits	323	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

S23IP_MOUSE
NC score	0.081200 (rank : 474)	θ value	6.88961 (rank : 526)
Query Neighborhood Hits	593	Target Neighborhood Hits	363	Shared Neighborhood Hits	107
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

AFF2_MOUSE
NC score	0.080877 (rank : 475)	θ value	1.06291 (rank : 255)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

GAB2_MOUSE
NC score	0.080721 (rank : 476)	θ value	1.81305 (rank : 314)
Query Neighborhood Hits	593	Target Neighborhood Hits	220	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PRGC2_MOUSE
NC score	0.080540 (rank : 477)	θ value	0.163984 (rank : 158)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

SPR2D_MOUSE
NC score	0.080473 (rank : 478)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	593	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SH21B_HUMAN
NC score	0.080328 (rank : 479)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	593	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

TCGAP_MOUSE
NC score	0.080267 (rank : 480)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	593	Target Neighborhood Hits	409	Shared Neighborhood Hits	107
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ACINU_HUMAN
NC score	0.080257 (rank : 481)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	593	Target Neighborhood Hits	828	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

VCY1_HUMAN
NC score	0.080118 (rank : 482)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	593	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

SMCA4_HUMAN
NC score	0.079722 (rank : 483)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	593	Target Neighborhood Hits	597	Shared Neighborhood Hits	175
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

GAB2_HUMAN
NC score	0.079454 (rank : 484)	θ value	1.06291 (rank : 259)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

ARHGF_HUMAN
NC score	0.079384 (rank : 485)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	98
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

PARM1_HUMAN
NC score	0.079382 (rank : 486)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	593	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

ABI2_HUMAN
NC score	0.079290 (rank : 487)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	593	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

BIN1_HUMAN
NC score	0.078936 (rank : 488)	θ value	0.365318 (rank : 187)
Query Neighborhood Hits	593	Target Neighborhood Hits	335	Shared Neighborhood Hits	75
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

ANR11_HUMAN
NC score	0.078796 (rank : 489)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	593	Target Neighborhood Hits	1289	Shared Neighborhood Hits	168
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BAZ2A_HUMAN
NC score	0.078753 (rank : 490)	θ value	6.88961 (rank : 492)
Query Neighborhood Hits	593	Target Neighborhood Hits	780	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

GNDS_HUMAN
NC score	0.078696 (rank : 491)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	90
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

TAF6_MOUSE
NC score	0.078644 (rank : 492)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	593	Target Neighborhood Hits	110	Shared Neighborhood Hits	58
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

DAG1_MOUSE
NC score	0.078362 (rank : 493)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	593	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

ANTR1_MOUSE
NC score	0.078233 (rank : 494)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	593	Target Neighborhood Hits	143	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

PO6F2_HUMAN
NC score	0.078213 (rank : 495)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	593	Target Neighborhood Hits	618	Shared Neighborhood Hits	141
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

DAG1_HUMAN
NC score	0.078111 (rank : 496)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	593	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

PRRT3_MOUSE
NC score	0.078004 (rank : 497)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CNKR2_MOUSE
NC score	0.077869 (rank : 498)	θ value	0.0736092 (rank : 129)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.077814 (rank : 499)	θ value	0.0736092 (rank : 128)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PKHA4_HUMAN
NC score	0.077800 (rank : 500)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	593	Target Neighborhood Hits	283	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SYNPO_MOUSE
NC score	0.077769 (rank : 501)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	593	Target Neighborhood Hits	242	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CO4A5_HUMAN
NC score	0.077539 (rank : 502)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	593	Target Neighborhood Hits	383	Shared Neighborhood Hits	96
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

SH21A_HUMAN
NC score	0.077415 (rank : 503)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	593	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SOX13_HUMAN
NC score	0.077163 (rank : 504)	θ value	0.125558 (rank : 151)
Query Neighborhood Hits	593	Target Neighborhood Hits	464	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

CE025_HUMAN
NC score	0.076786 (rank : 505)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	593	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

ARID2_HUMAN
NC score	0.076755 (rank : 506)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	593	Target Neighborhood Hits	302	Shared Neighborhood Hits	74
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

SETBP_HUMAN
NC score	0.076521 (rank : 507)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

MTSS1_MOUSE
NC score	0.076499 (rank : 508)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	593	Target Neighborhood Hits	592	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ENAM_MOUSE
NC score	0.076396 (rank : 509)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	593	Target Neighborhood Hits	229	Shared Neighborhood Hits	75
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

LEUK_HUMAN
NC score	0.076293 (rank : 510)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

T22D4_HUMAN
NC score	0.075983 (rank : 511)	θ value	1.81305 (rank : 333)
Query Neighborhood Hits	593	Target Neighborhood Hits	403	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

PODXL_HUMAN
NC score	0.075937 (rank : 512)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	593	Target Neighborhood Hits	191	Shared Neighborhood Hits	44
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

AFF4_HUMAN
NC score	0.075437 (rank : 513)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	593	Target Neighborhood Hits	611	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

NPAS4_HUMAN
NC score	0.075353 (rank : 514)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

TFG_HUMAN
NC score	0.075223 (rank : 515)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	593	Target Neighborhood Hits	122	Shared Neighborhood Hits	51
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

MTSS1_HUMAN
NC score	0.075141 (rank : 516)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	593	Target Neighborhood Hits	504	Shared Neighborhood Hits	101
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

HCFC1_HUMAN
NC score	0.074985 (rank : 517)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	593	Target Neighborhood Hits	331	Shared Neighborhood Hits	85
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

SMRC1_HUMAN
NC score	0.074556 (rank : 518)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	593	Target Neighborhood Hits	375	Shared Neighborhood Hits	99
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

ZCHC5_HUMAN
NC score	0.074495 (rank : 519)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	593	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

AFF2_HUMAN
NC score	0.074426 (rank : 520)	θ value	1.38821 (rank : 272)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	56
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

MEGF9_HUMAN
NC score	0.074321 (rank : 521)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	593	Target Neighborhood Hits	557	Shared Neighborhood Hits	120
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TRDN_HUMAN
NC score	0.074195 (rank : 522)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	593	Target Neighborhood Hits	542	Shared Neighborhood Hits	66
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ANTR1_HUMAN
NC score	0.074193 (rank : 523)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

SHC2_HUMAN
NC score	0.074152 (rank : 524)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	25
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

AFF4_MOUSE
NC score	0.074149 (rank : 525)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	593	Target Neighborhood Hits	581	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CJ047_HUMAN
NC score	0.074139 (rank : 526)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	593	Target Neighborhood Hits	164	Shared Neighborhood Hits	60
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

NSD1_MOUSE
NC score	0.074130 (rank : 527)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	593	Target Neighborhood Hits	472	Shared Neighborhood Hits	99
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

HCFC1_MOUSE
NC score	0.074054 (rank : 528)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	593	Target Neighborhood Hits	348	Shared Neighborhood Hits	83
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCN2_HUMAN
NC score	0.074048 (rank : 529)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	593	Target Neighborhood Hits	369	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

PRDM2_HUMAN
NC score	0.074028 (rank : 530)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	593	Target Neighborhood Hits	1135	Shared Neighborhood Hits	184
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RIN2_MOUSE
NC score	0.074026 (rank : 531)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

CO3A1_MOUSE
NC score	0.073982 (rank : 532)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	593	Target Neighborhood Hits	466	Shared Neighborhood Hits	109
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_HUMAN
NC score	0.073814 (rank : 533)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	593	Target Neighborhood Hits	452	Shared Neighborhood Hits	107
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

TXND2_MOUSE
NC score	0.073812 (rank : 534)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	593	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

JIP1_MOUSE
NC score	0.073499 (rank : 535)	θ value	0.813845 (rank : 243)
Query Neighborhood Hits	593	Target Neighborhood Hits	259	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

RL1D1_HUMAN
NC score	0.073358 (rank : 536)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	52
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

PER2_MOUSE
NC score	0.073003 (rank : 537)	θ value	0.000786445 (rank : 42)
Query Neighborhood Hits	593	Target Neighborhood Hits	325	Shared Neighborhood Hits	65
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

IRS2_MOUSE
NC score	0.072961 (rank : 538)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	593	Target Neighborhood Hits	248	Shared Neighborhood Hits	93
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

SH21A_MOUSE
NC score	0.072772 (rank : 539)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	593	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

AMPH_HUMAN
NC score	0.072717 (rank : 540)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	593	Target Neighborhood Hits	455	Shared Neighborhood Hits	89
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

CRK_MOUSE
NC score	0.072712 (rank : 541)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	40
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

RBBP6_HUMAN
NC score	0.072554 (rank : 542)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	593	Target Neighborhood Hits	1135	Shared Neighborhood Hits	143
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

REXO1_HUMAN
NC score	0.072548 (rank : 543)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	593	Target Neighborhood Hits	242	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RASA1_HUMAN
NC score	0.072548 (rank : 544)	θ value	1.38821 (rank : 300)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

MEF2B_HUMAN
NC score	0.072453 (rank : 545)	θ value	0.62314 (rank : 225)
Query Neighborhood Hits	593	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

SFRS8_HUMAN
NC score	0.072420 (rank : 546)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	593	Target Neighborhood Hits	166	Shared Neighborhood Hits	43
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SYN3_HUMAN
NC score	0.072399 (rank : 547)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	86
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

SPR1B_HUMAN
NC score	0.072311 (rank : 548)	θ value	2.36792 (rank : 365)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	23
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SSBP3_HUMAN
NC score	0.072193 (rank : 549)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.072193 (rank : 550)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	56
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

SOX13_MOUSE
NC score	0.072116 (rank : 551)	θ value	0.0961366 (rank : 142)
Query Neighborhood Hits	593	Target Neighborhood Hits	495	Shared Neighborhood Hits	106
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SHC2_MOUSE
NC score	0.072089 (rank : 552)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

TAF6_HUMAN
NC score	0.072034 (rank : 553)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	593	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

SYN2_MOUSE
NC score	0.072029 (rank : 554)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	593	Target Neighborhood Hits	183	Shared Neighborhood Hits	98
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

ACD_HUMAN
NC score	0.071955 (rank : 555)	θ value	3.0926 (rank : 372)
Query Neighborhood Hits	593	Target Neighborhood Hits	143	Shared Neighborhood Hits	52
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

CBL_MOUSE
NC score	0.071947 (rank : 556)	θ value	0.125558 (rank : 147)
Query Neighborhood Hits	593	Target Neighborhood Hits	426	Shared Neighborhood Hits	75
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

SHAN2_MOUSE
NC score	0.071804 (rank : 557)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	593	Target Neighborhood Hits	446	Shared Neighborhood Hits	93
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

CO1A1_MOUSE
NC score	0.071718 (rank : 558)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	593	Target Neighborhood Hits	457	Shared Neighborhood Hits	104
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CRK_HUMAN
NC score	0.071702 (rank : 559)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	593	Target Neighborhood Hits	308	Shared Neighborhood Hits	35
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

LPP_MOUSE
NC score	0.071528 (rank : 560)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	593	Target Neighborhood Hits	247	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

SMRC1_MOUSE
NC score	0.071452 (rank : 561)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	593	Target Neighborhood Hits	459	Shared Neighborhood Hits	102
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

NFAC1_HUMAN
NC score	0.071246 (rank : 562)	θ value	1.81305 (rank : 327)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	112
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

RBBP6_MOUSE
NC score	0.070990 (rank : 563)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	593	Target Neighborhood Hits	1014	Shared Neighborhood Hits	150
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

YETS2_HUMAN
NC score	0.070967 (rank : 564)	θ value	0.813845 (rank : 253)
Query Neighborhood Hits	593	Target Neighborhood Hits	212	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

DAB1_HUMAN
NC score	0.070836 (rank : 565)	θ value	8.99809 (rank : 552)
Query Neighborhood Hits	593	Target Neighborhood Hits	219	Shared Neighborhood Hits	72
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

EMSY_MOUSE
NC score	0.070801 (rank : 566)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	593	Target Neighborhood Hits	294	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

GRAP_HUMAN
NC score	0.070712 (rank : 567)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ASPP2_HUMAN
NC score	0.070688 (rank : 568)	θ value	4.03905 (rank : 403)
Query Neighborhood Hits	593	Target Neighborhood Hits	1156	Shared Neighborhood Hits	144
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

TENS4_HUMAN
NC score	0.070602 (rank : 569)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	593	Target Neighborhood Hits	214	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

SOX30_HUMAN
NC score	0.070521 (rank : 570)	θ value	0.279714 (rank : 181)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	80
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

MAML3_HUMAN
NC score	0.070425 (rank : 571)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	593	Target Neighborhood Hits	323	Shared Neighborhood Hits	78
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

WNK2_HUMAN
NC score	0.070374 (rank : 572)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	593	Target Neighborhood Hits	1407	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZCPW1_MOUSE
NC score	0.070262 (rank : 573)	θ value	0.163984 (rank : 162)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

MYO15_MOUSE
NC score	0.070158 (rank : 574)	θ value	0.0193708 (rank : 95)
Query Neighborhood Hits	593	Target Neighborhood Hits	467	Shared Neighborhood Hits	135
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RP3A_MOUSE
NC score	0.069991 (rank : 575)	θ value	0.0961366 (rank : 140)
Query Neighborhood Hits	593	Target Neighborhood Hits	510	Shared Neighborhood Hits	109
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

APS_HUMAN
NC score	0.069988 (rank : 576)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ETV3_HUMAN
NC score	0.069912 (rank : 577)	θ value	0.0431538 (rank : 112)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	76
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

R3HD1_HUMAN
NC score	0.069888 (rank : 578)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RC3H1_HUMAN
NC score	0.069754 (rank : 579)	θ value	0.0252991 (rank : 101)
Query Neighborhood Hits	593	Target Neighborhood Hits	433	Shared Neighborhood Hits	69
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CN092_MOUSE
NC score	0.069565 (rank : 580)	θ value	1.06291 (rank : 257)
Query Neighborhood Hits	593	Target Neighborhood Hits	206	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

AKA12_HUMAN
NC score	0.069509 (rank : 581)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	593	Target Neighborhood Hits	825	Shared Neighborhood Hits	91
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

COHA1_HUMAN
NC score	0.069489 (rank : 582)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	593	Target Neighborhood Hits	400	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CT174_HUMAN
NC score	0.069450 (rank : 583)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

GNAS1_HUMAN
NC score	0.069348 (rank : 584)	θ value	5.27518 (rank : 449)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	80
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

VCX2_HUMAN
NC score	0.069341 (rank : 585)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	593	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H322, Q9P0H5	Gene names	VCX2, VCX2R, VCXB
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 2 (VCX-B protein) (Variably charged protein X-B) (Variable charge protein on X with two repeats) (VCX-2r).

JIP1_HUMAN
NC score	0.069258 (rank : 586)	θ value	1.81305 (rank : 319)
Query Neighborhood Hits	593	Target Neighborhood Hits	271	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

RAI1_MOUSE
NC score	0.069190 (rank : 587)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	593	Target Neighborhood Hits	344	Shared Neighborhood Hits	83
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

GTSE1_MOUSE
NC score	0.069007 (rank : 588)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	593	Target Neighborhood Hits	245	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

NCK1_HUMAN
NC score	0.068995 (rank : 589)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	35
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

LNK_MOUSE
NC score	0.068959 (rank : 590)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	14
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

CO1A1_HUMAN
NC score	0.068818 (rank : 591)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	593	Target Neighborhood Hits	475	Shared Neighborhood Hits	101
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SOX30_MOUSE
NC score	0.068589 (rank : 592)	θ value	5.27518 (rank : 469)
Query Neighborhood Hits	593	Target Neighborhood Hits	374	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SYN3_MOUSE
NC score	0.068359 (rank : 593)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

LEUK_MOUSE
NC score	0.068242 (rank : 594)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	43
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

ATX1_MOUSE
NC score	0.068156 (rank : 595)	θ value	1.38821 (rank : 274)
Query Neighborhood Hits	593	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

DCP1A_HUMAN
NC score	0.068052 (rank : 596)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

APXL_HUMAN
NC score	0.068028 (rank : 597)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	593	Target Neighborhood Hits	553	Shared Neighborhood Hits	95
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BRD8_MOUSE
NC score	0.067980 (rank : 598)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	593	Target Neighborhood Hits	422	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

GRAP_MOUSE
NC score	0.067821 (rank : 599)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	593	Target Neighborhood Hits	309	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SAPS1_MOUSE
NC score	0.067788 (rank : 600)	θ value	0.813845 (rank : 250)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

TRI66_MOUSE
NC score	0.067562 (rank : 601)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	593	Target Neighborhood Hits	491	Shared Neighborhood Hits	111
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ZN385_HUMAN
NC score	0.067549 (rank : 602)	θ value	5.27518 (rank : 483)
Query Neighborhood Hits	593	Target Neighborhood Hits	614	Shared Neighborhood Hits	97
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SPR1A_HUMAN
NC score	0.067507 (rank : 603)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	593	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

GRAP2_HUMAN
NC score	0.067494 (rank : 604)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	593	Target Neighborhood Hits	304	Shared Neighborhood Hits	34
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

SOS1_HUMAN
NC score	0.067457 (rank : 605)	θ value	0.62314 (rank : 227)
Query Neighborhood Hits	593	Target Neighborhood Hits	274	Shared Neighborhood Hits	90
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

RSMN_HUMAN
NC score	0.067272 (rank : 606)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	593	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.067272 (rank : 607)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	593	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

CJ108_HUMAN
NC score	0.067221 (rank : 608)	θ value	5.27518 (rank : 441)
Query Neighborhood Hits	593	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

PHLA1_HUMAN
NC score	0.067139 (rank : 609)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	593	Target Neighborhood Hits	121	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

RAI1_HUMAN
NC score	0.067038 (rank : 610)	θ value	8.99809 (rank : 581)
Query Neighborhood Hits	593	Target Neighborhood Hits	360	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CDN1C_MOUSE
NC score	0.066806 (rank : 611)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	593	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CAC1G_HUMAN
NC score	0.066736 (rank : 612)	θ value	0.000270298 (rank : 35)
Query Neighborhood Hits	593	Target Neighborhood Hits	587	Shared Neighborhood Hits	116
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

NUMB_MOUSE
NC score	0.066657 (rank : 613)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	593	Target Neighborhood Hits	91	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

PP1RA_HUMAN
NC score	0.066630 (rank : 614)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

RFIP1_HUMAN
NC score	0.066598 (rank : 615)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	593	Target Neighborhood Hits	236	Shared Neighborhood Hits	68
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

ECM1_MOUSE
NC score	0.066544 (rank : 616)	θ value	3.0926 (rank : 379)
Query Neighborhood Hits	593	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

NHS_HUMAN
NC score	0.066463 (rank : 617)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	593	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

HCLS1_HUMAN
NC score	0.066371 (rank : 618)	θ value	1.06291 (rank : 262)
Query Neighborhood Hits	593	Target Neighborhood Hits	358	Shared Neighborhood Hits	87
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

PODXL_MOUSE
NC score	0.066360 (rank : 619)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	593	Target Neighborhood Hits	130	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

HNRL1_MOUSE
NC score	0.066317 (rank : 620)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

CITE4_MOUSE
NC score	0.066262 (rank : 621)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	593	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

PF21B_MOUSE
NC score	0.065857 (rank : 622)	θ value	6.88961 (rank : 522)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	67
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SOS1_MOUSE
NC score	0.065745 (rank : 623)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	593	Target Neighborhood Hits	281	Shared Neighborhood Hits	94
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

FBLI1_MOUSE
NC score	0.065691 (rank : 624)	θ value	1.06291 (rank : 258)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	69
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

GPS2_HUMAN
NC score	0.065687 (rank : 625)	θ value	1.06291 (rank : 261)
Query Neighborhood Hits	593	Target Neighborhood Hits	459	Shared Neighborhood Hits	67
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

IL4RA_MOUSE
NC score	0.065490 (rank : 626)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	50
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PGCA_HUMAN
NC score	0.065330 (rank : 627)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	593	Target Neighborhood Hits	821	Shared Neighborhood Hits	113
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

COIA1_MOUSE
NC score	0.065262 (rank : 628)	θ value	8.99809 (rank : 546)
Query Neighborhood Hits	593	Target Neighborhood Hits	481	Shared Neighborhood Hits	110
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MAP2_HUMAN
NC score	0.065261 (rank : 629)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	593	Target Neighborhood Hits	348	Shared Neighborhood Hits	71
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

JIP2_HUMAN
NC score	0.065137 (rank : 630)	θ value	6.88961 (rank : 511)
Query Neighborhood Hits	593	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

NCK2_HUMAN
NC score	0.065090 (rank : 631)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SPR2G_MOUSE
NC score	0.065061 (rank : 632)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	593	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

DAB2_MOUSE
NC score	0.065045 (rank : 633)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

TRI66_HUMAN
NC score	0.064911 (rank : 634)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	593	Target Neighborhood Hits	479	Shared Neighborhood Hits	101
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UBP2L_MOUSE
NC score	0.064902 (rank : 635)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	45
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

CASL_MOUSE
NC score	0.064663 (rank : 636)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	41
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

SPR2E_MOUSE
NC score	0.064493 (rank : 637)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	593	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

CRKL_HUMAN
NC score	0.064381 (rank : 638)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	593	Target Neighborhood Hits	313	Shared Neighborhood Hits	34
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

SRCA_HUMAN
NC score	0.064114 (rank : 639)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	593	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

HCN2_MOUSE
NC score	0.064107 (rank : 640)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	135
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

EPN3_MOUSE
NC score	0.063859 (rank : 641)	θ value	5.27518 (rank : 445)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	90
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

DACT1_HUMAN
NC score	0.063854 (rank : 642)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

NCA11_MOUSE
NC score	0.063776 (rank : 643)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	593	Target Neighborhood Hits	661	Shared Neighborhood Hits	125
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

IGEB_MOUSE
NC score	0.063497 (rank : 644)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	593	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

EVL_HUMAN
NC score	0.063442 (rank : 645)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

MKL2_HUMAN
NC score	0.063316 (rank : 646)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	593	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

CUTL1_MOUSE
NC score	0.063069 (rank : 647)	θ value	0.0431538 (rank : 111)
Query Neighborhood Hits	593	Target Neighborhood Hits	1620	Shared Neighborhood Hits	151
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

BRD3_HUMAN
NC score	0.063067 (rank : 648)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	593	Target Neighborhood Hits	369	Shared Neighborhood Hits	68
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

ZAN_MOUSE
NC score	0.063003 (rank : 649)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	593	Target Neighborhood Hits	808	Shared Neighborhood Hits	70
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

COHA1_MOUSE
NC score	0.062997 (rank : 650)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	593	Target Neighborhood Hits	414	Shared Neighborhood Hits	97
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CEND1_MOUSE
NC score	0.062952 (rank : 651)	θ value	0.0961366 (rank : 132)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

MEF2B_MOUSE
NC score	0.062863 (rank : 652)	θ value	4.03905 (rank : 413)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	58
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

LNK_HUMAN
NC score	0.062849 (rank : 653)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	593	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

SYNJ2_HUMAN
NC score	0.062657 (rank : 654)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	593	Target Neighborhood Hits	136	Shared Neighborhood Hits	62
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

RFX1_MOUSE
NC score	0.062596 (rank : 655)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	90
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

INP5E_HUMAN
NC score	0.062582 (rank : 656)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

PLCG1_MOUSE
NC score	0.062506 (rank : 657)	θ value	5.27518 (rank : 462)
Query Neighborhood Hits	593	Target Neighborhood Hits	314	Shared Neighborhood Hits	32
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SHC3_MOUSE
NC score	0.062315 (rank : 658)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	593	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

BRD3_MOUSE
NC score	0.062297 (rank : 659)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	593	Target Neighborhood Hits	402	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

PF21B_HUMAN
NC score	0.062188 (rank : 660)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	593	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

GNAS3_HUMAN
NC score	0.062155 (rank : 661)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	593	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

RSF1_HUMAN
NC score	0.062141 (rank : 662)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	593	Target Neighborhood Hits	539	Shared Neighborhood Hits	69
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CASL_HUMAN
NC score	0.061968 (rank : 663)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	593	Target Neighborhood Hits	259	Shared Neighborhood Hits	47
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

UBP2L_HUMAN
NC score	0.061648 (rank : 664)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

SPR2F_MOUSE
NC score	0.061647 (rank : 665)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	593	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

PLCG1_HUMAN
NC score	0.061640 (rank : 666)	θ value	5.27518 (rank : 461)
Query Neighborhood Hits	593	Target Neighborhood Hits	293	Shared Neighborhood Hits	29
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

BCAR3_MOUSE
NC score	0.061604 (rank : 667)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	593	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

EMSY_HUMAN
NC score	0.061579 (rank : 668)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	593	Target Neighborhood Hits	296	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

TACC2_MOUSE
NC score	0.061511 (rank : 669)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	593	Target Neighborhood Hits	774	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

NSD1_HUMAN
NC score	0.061489 (rank : 670)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	593	Target Neighborhood Hits	427	Shared Neighborhood Hits	100
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

GRAP2_MOUSE
NC score	0.061342 (rank : 671)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	593	Target Neighborhood Hits	297	Shared Neighborhood Hits	32
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

CJ026_MOUSE
NC score	0.061225 (rank : 672)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	593	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

COGA1_HUMAN
NC score	0.061157 (rank : 673)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	593	Target Neighborhood Hits	345	Shared Neighborhood Hits	74
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

GPTC8_HUMAN
NC score	0.061133 (rank : 674)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	593	Target Neighborhood Hits	366	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GON4L_MOUSE
NC score	0.060924 (rank : 675)	θ value	8.99809 (rank : 561)
Query Neighborhood Hits	593	Target Neighborhood Hits	455	Shared Neighborhood Hits	93
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ZIMP7_HUMAN
NC score	0.060854 (rank : 676)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	593	Target Neighborhood Hits	290	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PKHA6_MOUSE
NC score	0.060655 (rank : 677)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	593	Target Neighborhood Hits	591	Shared Neighborhood Hits	107
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

HCN4_MOUSE
NC score	0.060647 (rank : 678)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	593	Target Neighborhood Hits	284	Shared Neighborhood Hits	118
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

RIN2_HUMAN
NC score	0.060520 (rank : 679)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	593	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

SPR2I_MOUSE
NC score	0.060450 (rank : 680)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	593	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ATF5_HUMAN
NC score	0.060415 (rank : 681)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	593	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

NUMB_HUMAN
NC score	0.060343 (rank : 682)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	593	Target Neighborhood Hits	112	Shared Neighborhood Hits	35
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

AMPH_MOUSE
NC score	0.060259 (rank : 683)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	593	Target Neighborhood Hits	291	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

CRKL_MOUSE
NC score	0.060119 (rank : 684)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	593	Target Neighborhood Hits	307	Shared Neighborhood Hits	30
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SETD2_HUMAN
NC score	0.060014 (rank : 685)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	593	Target Neighborhood Hits	412	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

FYB_MOUSE
NC score	0.059860 (rank : 686)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	61
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MEF2D_MOUSE
NC score	0.059858 (rank : 687)	θ value	2.36792 (rank : 357)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	59
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

HSH2D_MOUSE
NC score	0.059800 (rank : 688)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	593	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

SHC1_HUMAN
NC score	0.059748 (rank : 689)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

TGON2_MOUSE
NC score	0.059697 (rank : 690)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	593	Target Neighborhood Hits	277	Shared Neighborhood Hits	48
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

VGF_HUMAN
NC score	0.059603 (rank : 691)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	593	Target Neighborhood Hits	167	Shared Neighborhood Hits	42
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

SHC3_HUMAN
NC score	0.059545 (rank : 692)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	593	Target Neighborhood Hits	155	Shared Neighborhood Hits	15
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

HN1L_HUMAN
NC score	0.059426 (rank : 693)	θ value	0.813845 (rank : 240)
Query Neighborhood Hits	593	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

ZN687_HUMAN
NC score	0.059335 (rank : 694)	θ value	0.0961366 (rank : 146)
Query Neighborhood Hits	593	Target Neighborhood Hits	1244	Shared Neighborhood Hits	163
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

DREB_MOUSE
NC score	0.059329 (rank : 695)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	593	Target Neighborhood Hits	446	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MEF2D_HUMAN
NC score	0.059252 (rank : 696)	θ value	2.36792 (rank : 356)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	66
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

NACA_MOUSE
NC score	0.059206 (rank : 697)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	593	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q60817	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha (Alpha-NAC) (Alpha-NAC/1.9.2).

MKL1_HUMAN
NC score	0.059187 (rank : 698)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	593	Target Neighborhood Hits	232	Shared Neighborhood Hits	77
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MAGD4_HUMAN
NC score	0.059139 (rank : 699)	θ value	1.38821 (rank : 291)
Query Neighborhood Hits	593	Target Neighborhood Hits	338	Shared Neighborhood Hits	85
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

SC24B_HUMAN
NC score	0.059121 (rank : 700)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	593	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

HGS_MOUSE
NC score	0.058956 (rank : 701)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	593	Target Neighborhood Hits	589	Shared Neighborhood Hits	106
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

3BP2_MOUSE
NC score	0.058903 (rank : 702)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	593	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CO8A2_HUMAN
NC score	0.058866 (rank : 703)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	593	Target Neighborhood Hits	299	Shared Neighborhood Hits	73
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

BCAR3_HUMAN
NC score	0.058865 (rank : 704)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	593	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

PER2_HUMAN
NC score	0.058792 (rank : 705)	θ value	4.03905 (rank : 417)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	61
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

ABI3_HUMAN
NC score	0.058767 (rank : 706)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AKAP2_MOUSE
NC score	0.058705 (rank : 707)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ZC313_HUMAN
NC score	0.058674 (rank : 708)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	593	Target Neighborhood Hits	772	Shared Neighborhood Hits	91
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

SPR2D_HUMAN
NC score	0.058636 (rank : 709)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	593	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

PLCG2_HUMAN
NC score	0.058632 (rank : 710)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	593	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

COAA1_HUMAN
NC score	0.058571 (rank : 711)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	593	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

NACA_HUMAN
NC score	0.058541 (rank : 712)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	593	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q13765, Q53A18, Q53G46	Gene names	NACA
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (Hom s 2.02).

GP152_HUMAN
NC score	0.058450 (rank : 713)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	593	Target Neighborhood Hits	636	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

DDEF1_MOUSE
NC score	0.058449 (rank : 714)	θ value	8.99809 (rank : 555)
Query Neighborhood Hits	593	Target Neighborhood Hits	592	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

AMELX_MOUSE
NC score	0.058383 (rank : 715)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	593	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	P63277, P45559, P70592, Q61293	Gene names	Amelx, Amel
Domain Architecture	No domain graphic available
Description	Amelogenin, X isoform precursor (Leucine-rich amelogenin peptide) (LRAP).

BLNK_HUMAN
NC score	0.058307 (rank : 716)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

RIMB1_HUMAN
NC score	0.058268 (rank : 717)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	593	Target Neighborhood Hits	1479	Shared Neighborhood Hits	168
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

UBP42_HUMAN
NC score	0.058264 (rank : 718)	θ value	1.38821 (rank : 303)
Query Neighborhood Hits	593	Target Neighborhood Hits	445	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

FOXN1_HUMAN
NC score	0.058205 (rank : 719)	θ value	0.00869519 (rank : 78)
Query Neighborhood Hits	593	Target Neighborhood Hits	377	Shared Neighborhood Hits	75
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

RTN1_HUMAN
NC score	0.058204 (rank : 720)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

DDEF2_HUMAN
NC score	0.058196 (rank : 721)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	593	Target Neighborhood Hits	599	Shared Neighborhood Hits	113
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CBL_HUMAN
NC score	0.058179 (rank : 722)	θ value	1.81305 (rank : 310)
Query Neighborhood Hits	593	Target Neighborhood Hits	353	Shared Neighborhood Hits	59
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

K1949_MOUSE
NC score	0.058156 (rank : 723)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

CNOT4_MOUSE
NC score	0.058034 (rank : 724)	θ value	5.27518 (rank : 443)
Query Neighborhood Hits	593	Target Neighborhood Hits	277	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

SH21B_MOUSE
NC score	0.057991 (rank : 725)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	593	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

NRX2B_HUMAN
NC score	0.057892 (rank : 726)	θ value	2.36792 (rank : 361)
Query Neighborhood Hits	593	Target Neighborhood Hits	481	Shared Neighborhood Hits	89
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

UBP36_HUMAN
NC score	0.057767 (rank : 727)	θ value	0.125558 (rank : 152)
Query Neighborhood Hits	593	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

GRB2_HUMAN
NC score	0.057755 (rank : 728)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	593	Target Neighborhood Hits	310	Shared Neighborhood Hits	33
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.057754 (rank : 729)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	593	Target Neighborhood Hits	312	Shared Neighborhood Hits	33
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

DDEF2_MOUSE
NC score	0.057677 (rank : 730)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	593	Target Neighborhood Hits	625	Shared Neighborhood Hits	119
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SREC2_HUMAN
NC score	0.057655 (rank : 731)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	593	Target Neighborhood Hits	645	Shared Neighborhood Hits	109
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

GORS2_HUMAN
NC score	0.057628 (rank : 732)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	593	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H8Y8, Q96I74, Q96K84, Q9H946, Q9UFW4	Gene names	GORASP2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) (Golgi phosphoprotein 6) (GOLPH6).

ENAM_HUMAN
NC score	0.057586 (rank : 733)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

RSMB_HUMAN
NC score	0.057330 (rank : 734)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	593	Target Neighborhood Hits	117	Shared Neighborhood Hits	45
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

MECP2_HUMAN
NC score	0.057148 (rank : 735)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	593	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

ZN598_MOUSE
NC score	0.057120 (rank : 736)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	593	Target Neighborhood Hits	255	Shared Neighborhood Hits	50
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

PDLI7_HUMAN
NC score	0.056898 (rank : 737)	θ value	0.0431538 (rank : 119)
Query Neighborhood Hits	593	Target Neighborhood Hits	547	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GON4L_HUMAN
NC score	0.056626 (rank : 738)	θ value	8.99809 (rank : 560)
Query Neighborhood Hits	593	Target Neighborhood Hits	555	Shared Neighborhood Hits	86
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

FBLI1_HUMAN
NC score	0.056602 (rank : 739)	θ value	0.279714 (rank : 175)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

COFA1_HUMAN
NC score	0.056566 (rank : 740)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	593	Target Neighborhood Hits	292	Shared Neighborhood Hits	69
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

DIAP2_MOUSE
NC score	0.056564 (rank : 741)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	593	Target Neighborhood Hits	260	Shared Neighborhood Hits	95
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

SHC1_MOUSE
NC score	0.056564 (rank : 742)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

G3PT_MOUSE
NC score	0.056502 (rank : 743)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	593	Target Neighborhood Hits	78	Shared Neighborhood Hits	55
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

ODO2_MOUSE
NC score	0.056446 (rank : 744)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

GORS2_MOUSE
NC score	0.056376 (rank : 745)	θ value	4.03905 (rank : 410)
Query Neighborhood Hits	593	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

CEND3_HUMAN
NC score	0.056240 (rank : 746)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	593	Target Neighborhood Hits	275	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

YETS2_MOUSE
NC score	0.056211 (rank : 747)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

HCN4_HUMAN
NC score	0.056204 (rank : 748)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	593	Target Neighborhood Hits	303	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

SPEG_MOUSE
NC score	0.056104 (rank : 749)	θ value	0.365318 (rank : 203)
Query Neighborhood Hits	593	Target Neighborhood Hits	1959	Shared Neighborhood Hits	266
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TACC2_HUMAN
NC score	0.056094 (rank : 750)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	593	Target Neighborhood Hits	856	Shared Neighborhood Hits	120
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

APS_MOUSE
NC score	0.055866 (rank : 751)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

RPGF1_HUMAN
NC score	0.055864 (rank : 752)	θ value	0.163984 (rank : 159)
Query Neighborhood Hits	593	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

GCNL2_HUMAN
NC score	0.055783 (rank : 753)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	593	Target Neighborhood Hits	159	Shared Neighborhood Hits	63
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

MAP2_MOUSE
NC score	0.055663 (rank : 754)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	593	Target Neighborhood Hits	342	Shared Neighborhood Hits	68
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

NCOR1_HUMAN
NC score	0.055631 (rank : 755)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	593	Target Neighborhood Hits	577	Shared Neighborhood Hits	104
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

BCAS1_MOUSE
NC score	0.055627 (rank : 756)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	593	Target Neighborhood Hits	215	Shared Neighborhood Hits	49
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

TP53B_HUMAN
NC score	0.055480 (rank : 757)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	593	Target Neighborhood Hits	413	Shared Neighborhood Hits	69
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ATBF1_MOUSE
NC score	0.055359 (rank : 758)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	593	Target Neighborhood Hits	1841	Shared Neighborhood Hits	223
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PININ_MOUSE
NC score	0.055338 (rank : 759)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	593	Target Neighborhood Hits	777	Shared Neighborhood Hits	100
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

TITIN_HUMAN
NC score	0.055338 (rank : 760)	θ value	4.03905 (rank : 430)
Query Neighborhood Hits	593	Target Neighborhood Hits	2923	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TENS4_MOUSE
NC score	0.055289 (rank : 761)	θ value	8.99809 (rank : 589)
Query Neighborhood Hits	593	Target Neighborhood Hits	225	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

LR37B_HUMAN
NC score	0.055277 (rank : 762)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	593	Target Neighborhood Hits	392	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

NCOR1_MOUSE
NC score	0.055189 (rank : 763)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	593	Target Neighborhood Hits	521	Shared Neighborhood Hits	95
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

FIP1_MOUSE
NC score	0.054966 (rank : 764)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	593	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

MORC2_HUMAN
NC score	0.054926 (rank : 765)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	593	Target Neighborhood Hits	207	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

ICAL_MOUSE
NC score	0.054776 (rank : 766)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	593	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

RP3A_HUMAN
NC score	0.054727 (rank : 767)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MAML1_MOUSE
NC score	0.054716 (rank : 768)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

DOCK4_HUMAN
NC score	0.054696 (rank : 769)	θ value	0.21417 (rank : 168)
Query Neighborhood Hits	593	Target Neighborhood Hits	237	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

CEND3_MOUSE
NC score	0.054688 (rank : 770)	θ value	3.0926 (rank : 377)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

FHOD1_MOUSE
NC score	0.054687 (rank : 771)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	593	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

TGON1_MOUSE
NC score	0.054581 (rank : 772)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	593	Target Neighborhood Hits	243	Shared Neighborhood Hits	42
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

RD23B_HUMAN
NC score	0.054471 (rank : 773)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	593	Target Neighborhood Hits	115	Shared Neighborhood Hits	35
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

GCX1_HUMAN
NC score	0.054411 (rank : 774)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

CO8A2_MOUSE
NC score	0.054371 (rank : 775)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	593	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

ESX1L_HUMAN
NC score	0.054303 (rank : 776)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	593	Target Neighborhood Hits	498	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

PKCB1_HUMAN
NC score	0.054221 (rank : 777)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	593	Target Neighborhood Hits	488	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SPEG_HUMAN
NC score	0.054118 (rank : 778)	θ value	6.88961 (rank : 533)
Query Neighborhood Hits	593	Target Neighborhood Hits	1762	Shared Neighborhood Hits	246
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ARMX2_HUMAN
NC score	0.054077 (rank : 779)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	43
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

IF4B_HUMAN
NC score	0.054067 (rank : 780)	θ value	1.38821 (rank : 288)
Query Neighborhood Hits	593	Target Neighborhood Hits	417	Shared Neighborhood Hits	71
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SPR2B_HUMAN
NC score	0.054011 (rank : 781)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	593	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

HNRL1_HUMAN
NC score	0.054011 (rank : 782)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

CDT1_MOUSE
NC score	0.053968 (rank : 783)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

TCF20_HUMAN
NC score	0.053954 (rank : 784)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	593	Target Neighborhood Hits	323	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

ZCH11_HUMAN
NC score	0.053829 (rank : 785)	θ value	1.38821 (rank : 305)
Query Neighborhood Hits	593	Target Neighborhood Hits	278	Shared Neighborhood Hits	62
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

MUCEN_MOUSE
NC score	0.053744 (rank : 786)	θ value	1.38821 (rank : 294)
Query Neighborhood Hits	593	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

SPR2G_HUMAN
NC score	0.053734 (rank : 787)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	593	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

FOG1_HUMAN
NC score	0.053723 (rank : 788)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	593	Target Neighborhood Hits	981	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

LMBL3_MOUSE
NC score	0.053673 (rank : 789)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	593	Target Neighborhood Hits	212	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

FOG1_MOUSE
NC score	0.053668 (rank : 790)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	593	Target Neighborhood Hits	1237	Shared Neighborhood Hits	199
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

T2FA_HUMAN
NC score	0.053570 (rank : 791)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

SF3B2_HUMAN
NC score	0.053400 (rank : 792)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	593	Target Neighborhood Hits	157	Shared Neighborhood Hits	45
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

TTC15_HUMAN
NC score	0.053368 (rank : 793)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	593	Target Neighborhood Hits	112	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

CCDC4_HUMAN
NC score	0.053314 (rank : 794)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	593	Target Neighborhood Hits	104	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

WDR33_HUMAN
NC score	0.053297 (rank : 795)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	593	Target Neighborhood Hits	638	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ABI3_MOUSE
NC score	0.053275 (rank : 796)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CEND_MOUSE
NC score	0.053275 (rank : 797)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	593	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JKC6, Q9DBA0	Gene names	Cend1, Bm88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

TM16H_HUMAN
NC score	0.053262 (rank : 798)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	593	Target Neighborhood Hits	139	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

OBF1_HUMAN
NC score	0.053116 (rank : 799)	θ value	4.03905 (rank : 416)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	55
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PB1_HUMAN
NC score	0.052957 (rank : 800)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	593	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

DAPP1_HUMAN
NC score	0.052920 (rank : 801)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	593	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

INVO_HUMAN
NC score	0.052918 (rank : 802)	θ value	0.163984 (rank : 157)
Query Neighborhood Hits	593	Target Neighborhood Hits	636	Shared Neighborhood Hits	71
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

SIN3A_HUMAN
NC score	0.052895 (rank : 803)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	593	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

DAB1_MOUSE
NC score	0.052767 (rank : 804)	θ value	6.88961 (rank : 499)
Query Neighborhood Hits	593	Target Neighborhood Hits	145	Shared Neighborhood Hits	50
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

SNPC4_MOUSE
NC score	0.052694 (rank : 805)	θ value	8.99809 (rank : 584)
Query Neighborhood Hits	593	Target Neighborhood Hits	237	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

DOCK4_MOUSE
NC score	0.052649 (rank : 806)	θ value	1.81305 (rank : 312)
Query Neighborhood Hits	593	Target Neighborhood Hits	210	Shared Neighborhood Hits	65
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

ALMS1_HUMAN
NC score	0.052646 (rank : 807)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	593	Target Neighborhood Hits	356	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

HSH2D_HUMAN
NC score	0.052524 (rank : 808)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	593	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

ABI1_HUMAN
NC score	0.052441 (rank : 809)	θ value	3.0926 (rank : 371)
Query Neighborhood Hits	593	Target Neighborhood Hits	257	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

DREB_HUMAN
NC score	0.052366 (rank : 810)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	593	Target Neighborhood Hits	450	Shared Neighborhood Hits	82
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

EMID2_HUMAN
NC score	0.052264 (rank : 811)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	593	Target Neighborhood Hits	226	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

JADE2_HUMAN
NC score	0.052164 (rank : 812)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

GCNL2_MOUSE
NC score	0.052152 (rank : 813)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

SPAG8_HUMAN
NC score	0.052103 (rank : 814)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	593	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

CO4A4_HUMAN
NC score	0.052076 (rank : 815)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	593	Target Neighborhood Hits	440	Shared Neighborhood Hits	87
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

FBSH_MOUSE
NC score	0.052052 (rank : 816)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	593	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

AMELY_HUMAN
NC score	0.051982 (rank : 817)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	593	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

SASH1_MOUSE
NC score	0.051793 (rank : 818)	θ value	5.27518 (rank : 466)
Query Neighborhood Hits	593	Target Neighborhood Hits	263	Shared Neighborhood Hits	68
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

ICAL_HUMAN
NC score	0.051667 (rank : 819)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	593	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

SH2D3_MOUSE
NC score	0.051569 (rank : 820)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	593	Target Neighborhood Hits	174	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

E2F4_HUMAN
NC score	0.051560 (rank : 821)	θ value	0.813845 (rank : 235)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	50
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

HXA3_MOUSE
NC score	0.051514 (rank : 822)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	593	Target Neighborhood Hits	558	Shared Neighborhood Hits	149
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

ZFHX2_HUMAN
NC score	0.051487 (rank : 823)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	593	Target Neighborhood Hits	1178	Shared Neighborhood Hits	133
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

AIRE_MOUSE
NC score	0.051402 (rank : 824)	θ value	3.0926 (rank : 373)
Query Neighborhood Hits	593	Target Neighborhood Hits	196	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

RIMS1_HUMAN
NC score	0.051397 (rank : 825)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	593	Target Neighborhood Hits	437	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

NUP62_MOUSE
NC score	0.051387 (rank : 826)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	593	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

B4GN4_HUMAN
NC score	0.051374 (rank : 827)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	593	Target Neighborhood Hits	131	Shared Neighborhood Hits	54
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

GA2L1_HUMAN
NC score	0.051298 (rank : 828)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	593	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

DCC_MOUSE
NC score	0.051296 (rank : 829)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	593	Target Neighborhood Hits	896	Shared Neighborhood Hits	124
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

TPO_MOUSE
NC score	0.051256 (rank : 830)	θ value	3.0926 (rank : 397)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	54
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TIF1G_MOUSE
NC score	0.051235 (rank : 831)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	593	Target Neighborhood Hits	498	Shared Neighborhood Hits	98
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CARD6_HUMAN
NC score	0.051222 (rank : 832)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	593	Target Neighborhood Hits	145	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CENPT_MOUSE
NC score	0.051145 (rank : 833)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	593	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

EVL_MOUSE
NC score	0.051082 (rank : 834)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	593	Target Neighborhood Hits	203	Shared Neighborhood Hits	60
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

CNKR1_HUMAN
NC score	0.051075 (rank : 835)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	593	Target Neighborhood Hits	154	Shared Neighborhood Hits	38
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CSF1_MOUSE
NC score	0.051047 (rank : 836)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	593	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

TCF20_MOUSE
NC score	0.050924 (rank : 837)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	593	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

CUTL1_HUMAN
NC score	0.050782 (rank : 838)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	593	Target Neighborhood Hits	1574	Shared Neighborhood Hits	141
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CO5A2_HUMAN
NC score	0.050734 (rank : 839)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	593	Target Neighborhood Hits	760	Shared Neighborhood Hits	104
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

NUP62_HUMAN
NC score	0.050677 (rank : 840)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	593	Target Neighborhood Hits	195	Shared Neighborhood Hits	34
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

CBLB_MOUSE
NC score	0.050506 (rank : 841)	θ value	5.27518 (rank : 438)
Query Neighborhood Hits	593	Target Neighborhood Hits	277	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CNTRB_MOUSE
NC score	0.050480 (rank : 842)	θ value	0.0431538 (rank : 110)
Query Neighborhood Hits	593	Target Neighborhood Hits	1029	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

RTN1_MOUSE
NC score	0.050385 (rank : 843)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	593	Target Neighborhood Hits	189	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

BIN1_MOUSE
NC score	0.050343 (rank : 844)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	593	Target Neighborhood Hits	283	Shared Neighborhood Hits	66
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

K1210_HUMAN
NC score	0.050286 (rank : 845)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	593	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

EVI2B_MOUSE
NC score	0.050215 (rank : 846)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	593	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

ZN438_HUMAN
NC score	0.049903 (rank : 847)	θ value	1.69304e-06 (rank : 21)
Query Neighborhood Hits	593	Target Neighborhood Hits	906	Shared Neighborhood Hits	99
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

JIP3_HUMAN
NC score	0.049320 (rank : 848)	θ value	0.813845 (rank : 244)
Query Neighborhood Hits	593	Target Neighborhood Hits	1039	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CBLB_HUMAN
NC score	0.049165 (rank : 849)	θ value	5.27518 (rank : 437)
Query Neighborhood Hits	593	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

ZN409_HUMAN
NC score	0.048997 (rank : 850)	θ value	0.813845 (rank : 254)
Query Neighborhood Hits	593	Target Neighborhood Hits	842	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

PLXB1_HUMAN
NC score	0.048756 (rank : 851)	θ value	6.88961 (rank : 523)
Query Neighborhood Hits	593	Target Neighborhood Hits	360	Shared Neighborhood Hits	96
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

DCP1B_HUMAN
NC score	0.048658 (rank : 852)	θ value	8.99809 (rank : 554)
Query Neighborhood Hits	593	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

GA2L2_HUMAN
NC score	0.048552 (rank : 853)	θ value	8.99809 (rank : 558)
Query Neighborhood Hits	593	Target Neighborhood Hits	175	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

AAK1_HUMAN
NC score	0.048122 (rank : 854)	θ value	2.36792 (rank : 338)
Query Neighborhood Hits	593	Target Neighborhood Hits	1077	Shared Neighborhood Hits	142
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

FOXN1_MOUSE
NC score	0.047860 (rank : 855)	θ value	0.0961366 (rank : 135)
Query Neighborhood Hits	593	Target Neighborhood Hits	300	Shared Neighborhood Hits	58
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

SOS2_HUMAN
NC score	0.047346 (rank : 856)	θ value	6.88961 (rank : 531)
Query Neighborhood Hits	593	Target Neighborhood Hits	193	Shared Neighborhood Hits	60
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SI1L3_HUMAN
NC score	0.047321 (rank : 857)	θ value	0.47712 (rank : 215)
Query Neighborhood Hits	593	Target Neighborhood Hits	305	Shared Neighborhood Hits	75
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

CRSP7_HUMAN
NC score	0.046748 (rank : 858)	θ value	8.99809 (rank : 547)
Query Neighborhood Hits	593	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

MMAC_HUMAN
NC score	0.046242 (rank : 859)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	593	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

PHF3_HUMAN
NC score	0.046189 (rank : 860)	θ value	1.38821 (rank : 299)
Query Neighborhood Hits	593	Target Neighborhood Hits	419	Shared Neighborhood Hits	49
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

YAP1_HUMAN
NC score	0.046156 (rank : 861)	θ value	3.0926 (rank : 401)
Query Neighborhood Hits	593	Target Neighborhood Hits	173	Shared Neighborhood Hits	56
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

HSF1_MOUSE
NC score	0.046045 (rank : 862)	θ value	2.36792 (rank : 352)
Query Neighborhood Hits	593	Target Neighborhood Hits	267	Shared Neighborhood Hits	71
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

ELK4_HUMAN
NC score	0.045467 (rank : 863)	θ value	0.813845 (rank : 236)
Query Neighborhood Hits	593	Target Neighborhood Hits	184	Shared Neighborhood Hits	49
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

RNF25_HUMAN
NC score	0.045421 (rank : 864)	θ value	4.03905 (rank : 425)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

DOK2_MOUSE
NC score	0.045092 (rank : 865)	θ value	0.813845 (rank : 234)
Query Neighborhood Hits	593	Target Neighborhood Hits	244	Shared Neighborhood Hits	55
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

MAST4_HUMAN
NC score	0.044886 (rank : 866)	θ value	0.0330416 (rank : 105)
Query Neighborhood Hits	593	Target Neighborhood Hits	1804	Shared Neighborhood Hits	220
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ACK1_HUMAN
NC score	0.044495 (rank : 867)	θ value	0.0148317 (rank : 88)
Query Neighborhood Hits	593	Target Neighborhood Hits	1140	Shared Neighborhood Hits	178
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

REPS2_HUMAN
NC score	0.044178 (rank : 868)	θ value	6.88961 (rank : 525)
Query Neighborhood Hits	593	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

PO6F1_MOUSE
NC score	0.043813 (rank : 869)	θ value	0.125558 (rank : 150)
Query Neighborhood Hits	593	Target Neighborhood Hits	581	Shared Neighborhood Hits	83
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

CNOT4_HUMAN
NC score	0.043772 (rank : 870)	θ value	3.0926 (rank : 378)
Query Neighborhood Hits	593	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RHG25_MOUSE
NC score	0.043139 (rank : 871)	θ value	1.06291 (rank : 267)
Query Neighborhood Hits	593	Target Neighborhood Hits	492	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

WDR46_MOUSE
NC score	0.042885 (rank : 872)	θ value	8.99809 (rank : 592)
Query Neighborhood Hits	593	Target Neighborhood Hits	243	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

AFAD_HUMAN
NC score	0.042545 (rank : 873)	θ value	5.27518 (rank : 433)
Query Neighborhood Hits	593	Target Neighborhood Hits	689	Shared Neighborhood Hits	77
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DLG5_HUMAN
NC score	0.042472 (rank : 874)	θ value	0.21417 (rank : 167)
Query Neighborhood Hits	593	Target Neighborhood Hits	1088	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

NRX2A_HUMAN
NC score	0.042460 (rank : 875)	θ value	2.36792 (rank : 360)
Query Neighborhood Hits	593	Target Neighborhood Hits	614	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PF21A_HUMAN
NC score	0.041601 (rank : 876)	θ value	4.03905 (rank : 418)
Query Neighborhood Hits	593	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

STAT2_MOUSE
NC score	0.041596 (rank : 877)	θ value	0.0961366 (rank : 144)
Query Neighborhood Hits	593	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

NEB2_MOUSE
NC score	0.041153 (rank : 878)	θ value	1.81305 (rank : 326)
Query Neighborhood Hits	593	Target Neighborhood Hits	889	Shared Neighborhood Hits	71
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

STAR8_HUMAN
NC score	0.040736 (rank : 879)	θ value	0.21417 (rank : 172)
Query Neighborhood Hits	593	Target Neighborhood Hits	216	Shared Neighborhood Hits	43
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

NIPA_HUMAN
NC score	0.040697 (rank : 880)	θ value	1.38821 (rank : 295)
Query Neighborhood Hits	593	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

AATK_HUMAN
NC score	0.040658 (rank : 881)	θ value	0.0431538 (rank : 109)
Query Neighborhood Hits	593	Target Neighborhood Hits	1243	Shared Neighborhood Hits	146
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

RECQ5_HUMAN
NC score	0.040488 (rank : 882)	θ value	2.36792 (rank : 364)
Query Neighborhood Hits	593	Target Neighborhood Hits	390	Shared Neighborhood Hits	75
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ZC11A_HUMAN
NC score	0.039825 (rank : 883)	θ value	6.88961 (rank : 538)
Query Neighborhood Hits	593	Target Neighborhood Hits	170	Shared Neighborhood Hits	28
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

TRAK2_HUMAN
NC score	0.039610 (rank : 884)	θ value	0.365318 (rank : 206)
Query Neighborhood Hits	593	Target Neighborhood Hits	476	Shared Neighborhood Hits	32
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

ACK1_MOUSE
NC score	0.039571 (rank : 885)	θ value	0.21417 (rank : 163)
Query Neighborhood Hits	593	Target Neighborhood Hits	1080	Shared Neighborhood Hits	157
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CSPG3_HUMAN
NC score	0.039533 (rank : 886)	θ value	0.21417 (rank : 166)
Query Neighborhood Hits	593	Target Neighborhood Hits	676	Shared Neighborhood Hits	89
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ZC11A_MOUSE
NC score	0.039530 (rank : 887)	θ value	4.03905 (rank : 432)
Query Neighborhood Hits	593	Target Neighborhood Hits	216	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

BCOR_HUMAN
NC score	0.039393 (rank : 888)	θ value	6.88961 (rank : 494)
Query Neighborhood Hits	593	Target Neighborhood Hits	609	Shared Neighborhood Hits	94
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ITSN1_MOUSE
NC score	0.039318 (rank : 889)	θ value	1.81305 (rank : 318)
Query Neighborhood Hits	593	Target Neighborhood Hits	1669	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TRIP6_HUMAN
NC score	0.039157 (rank : 890)	θ value	5.27518 (rank : 478)
Query Neighborhood Hits	593	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

POLS_MOUSE
NC score	0.039088 (rank : 891)	θ value	0.279714 (rank : 180)
Query Neighborhood Hits	593	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

ZN687_MOUSE
NC score	0.038781 (rank : 892)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	593	Target Neighborhood Hits	913	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MAGD1_HUMAN
NC score	0.038613 (rank : 893)	θ value	5.27518 (rank : 454)
Query Neighborhood Hits	593	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

NECD_MOUSE
NC score	0.038485 (rank : 894)	θ value	6.88961 (rank : 520)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

PHLB2_MOUSE
NC score	0.038472 (rank : 895)	θ value	3.0926 (rank : 387)
Query Neighborhood Hits	593	Target Neighborhood Hits	1016	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

IRF2_MOUSE
NC score	0.038238 (rank : 896)	θ value	0.0113563 (rank : 85)
Query Neighborhood Hits	593	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

ZC3H3_MOUSE
NC score	0.038033 (rank : 897)	θ value	6.88961 (rank : 539)
Query Neighborhood Hits	593	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ITSN1_HUMAN
NC score	0.037844 (rank : 898)	θ value	0.813845 (rank : 242)
Query Neighborhood Hits	593	Target Neighborhood Hits	1757	Shared Neighborhood Hits	145
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SFRS4_MOUSE
NC score	0.037518 (rank : 899)	θ value	5.27518 (rank : 468)
Query Neighborhood Hits	593	Target Neighborhood Hits	406	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

ATF7_HUMAN
NC score	0.037379 (rank : 900)	θ value	6.88961 (rank : 488)
Query Neighborhood Hits	593	Target Neighborhood Hits	333	Shared Neighborhood Hits	50
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ZN516_MOUSE
NC score	0.037342 (rank : 901)	θ value	0.0252991 (rank : 102)
Query Neighborhood Hits	593	Target Neighborhood Hits	1197	Shared Neighborhood Hits	140
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

FOXJ2_HUMAN
NC score	0.037309 (rank : 902)	θ value	4.03905 (rank : 409)
Query Neighborhood Hits	593	Target Neighborhood Hits	239	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

TULP1_MOUSE
NC score	0.037223 (rank : 903)	θ value	3.0926 (rank : 399)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

ERF_HUMAN
NC score	0.037042 (rank : 904)	θ value	3.0926 (rank : 380)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

G137B_HUMAN
NC score	0.036668 (rank : 905)	θ value	1.38821 (rank : 286)
Query Neighborhood Hits	593	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

CAF1B_MOUSE
NC score	0.036084 (rank : 906)	θ value	4.03905 (rank : 406)
Query Neighborhood Hits	593	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CEP68_HUMAN
NC score	0.036060 (rank : 907)	θ value	5.27518 (rank : 440)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

GCP6_HUMAN
NC score	0.035808 (rank : 908)	θ value	2.36792 (rank : 347)
Query Neighborhood Hits	593	Target Neighborhood Hits	295	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

C2TA_HUMAN
NC score	0.035681 (rank : 909)	θ value	8.99809 (rank : 545)
Query Neighborhood Hits	593	Target Neighborhood Hits	190	Shared Neighborhood Hits	51
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

NOTC2_HUMAN
NC score	0.035448 (rank : 910)	θ value	0.0431538 (rank : 118)
Query Neighborhood Hits	593	Target Neighborhood Hits	1113	Shared Neighborhood Hits	114
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

COA2_HUMAN
NC score	0.035445 (rank : 911)	θ value	2.36792 (rank : 343)
Query Neighborhood Hits	593	Target Neighborhood Hits	184	Shared Neighborhood Hits	50
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

AAK1_MOUSE
NC score	0.035178 (rank : 912)	θ value	6.88961 (rank : 485)
Query Neighborhood Hits	593	Target Neighborhood Hits	1051	Shared Neighborhood Hits	125
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ETV3_MOUSE
NC score	0.035074 (rank : 913)	θ value	5.27518 (rank : 446)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

TACC1_MOUSE
NC score	0.035042 (rank : 914)	θ value	5.27518 (rank : 472)
Query Neighborhood Hits	593	Target Neighborhood Hits	667	Shared Neighborhood Hits	71
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

ANK3_HUMAN
NC score	0.034807 (rank : 915)	θ value	2.36792 (rank : 340)
Query Neighborhood Hits	593	Target Neighborhood Hits	853	Shared Neighborhood Hits	103
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

RHG25_HUMAN
NC score	0.034661 (rank : 916)	θ value	3.0926 (rank : 389)
Query Neighborhood Hits	593	Target Neighborhood Hits	550	Shared Neighborhood Hits	55
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

STAT6_HUMAN
NC score	0.034643 (rank : 917)	θ value	0.279714 (rank : 182)
Query Neighborhood Hits	593	Target Neighborhood Hits	132	Shared Neighborhood Hits	31
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

THAP7_MOUSE
NC score	0.034521 (rank : 918)	θ value	1.06291 (rank : 270)
Query Neighborhood Hits	593	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

MDN1_HUMAN
NC score	0.034490 (rank : 919)	θ value	6.88961 (rank : 517)
Query Neighborhood Hits	593	Target Neighborhood Hits	662	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NIPA_MOUSE
NC score	0.034354 (rank : 920)	θ value	8.99809 (rank : 572)
Query Neighborhood Hits	593	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

GP152_MOUSE
NC score	0.034042 (rank : 921)	θ value	5.27518 (rank : 450)
Query Neighborhood Hits	593	Target Neighborhood Hits	607	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

PDLI5_HUMAN
NC score	0.033707 (rank : 922)	θ value	8.99809 (rank : 576)
Query Neighborhood Hits	593	Target Neighborhood Hits	322	Shared Neighborhood Hits	42
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

NOTC2_MOUSE
NC score	0.033649 (rank : 923)	θ value	0.00869519 (rank : 80)
Query Neighborhood Hits	593	Target Neighborhood Hits	1069	Shared Neighborhood Hits	98
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AMBN_HUMAN
NC score	0.032978 (rank : 924)	θ value	2.36792 (rank : 339)
Query Neighborhood Hits	593	Target Neighborhood Hits	107	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

HLF_HUMAN
NC score	0.032961 (rank : 925)	θ value	1.81305 (rank : 316)
Query Neighborhood Hits	593	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

ATF7_MOUSE
NC score	0.032913 (rank : 926)	θ value	6.88961 (rank : 489)
Query Neighborhood Hits	593	Target Neighborhood Hits	286	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

TXLNB_MOUSE
NC score	0.032839 (rank : 927)	θ value	3.0926 (rank : 400)
Query Neighborhood Hits	593	Target Neighborhood Hits	640	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

AKAP2_HUMAN
NC score	0.032440 (rank : 928)	θ value	5.27518 (rank : 434)
Query Neighborhood Hits	593	Target Neighborhood Hits	507	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

HLF_MOUSE
NC score	0.032209 (rank : 929)	θ value	1.81305 (rank : 317)
Query Neighborhood Hits	593	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

DHX57_HUMAN
NC score	0.031939 (rank : 930)	θ value	0.0193708 (rank : 94)
Query Neighborhood Hits	593	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

SYGP1_HUMAN
NC score	0.031233 (rank : 931)	θ value	0.279714 (rank : 183)
Query Neighborhood Hits	593	Target Neighborhood Hits	589	Shared Neighborhood Hits	43
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

TAB2_MOUSE
NC score	0.030992 (rank : 932)	θ value	4.03905 (rank : 429)
Query Neighborhood Hits	593	Target Neighborhood Hits	245	Shared Neighborhood Hits	42
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

GRIP2_HUMAN
NC score	0.030862 (rank : 933)	θ value	0.62314 (rank : 223)
Query Neighborhood Hits	593	Target Neighborhood Hits	256	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

ADA12_MOUSE
NC score	0.030770 (rank : 934)	θ value	0.21417 (rank : 164)
Query Neighborhood Hits	593	Target Neighborhood Hits	474	Shared Neighborhood Hits	93
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

RN165_HUMAN
NC score	0.030556 (rank : 935)	θ value	0.365318 (rank : 201)
Query Neighborhood Hits	593	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

MA1B1_HUMAN
NC score	0.030428 (rank : 936)	θ value	1.81305 (rank : 322)
Query Neighborhood Hits	593	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

CCD21_MOUSE
NC score	0.030400 (rank : 937)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	593	Target Neighborhood Hits	1135	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

REC8L_MOUSE
NC score	0.030222 (rank : 938)	θ value	2.36792 (rank : 363)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C5S7, Q3UIN9, Q9JK52	Gene names	Rec8L1, Rec8
Domain Architecture
Description	Meiotic recombination protein REC8-like 1 (Cohesin Rec8p).

P66A_HUMAN
NC score	0.029769 (rank : 939)	θ value	8.99809 (rank : 574)
Query Neighborhood Hits	593	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

INP5E_MOUSE
NC score	0.029724 (rank : 940)	θ value	4.03905 (rank : 411)
Query Neighborhood Hits	593	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

NDF1_MOUSE
NC score	0.029507 (rank : 941)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	593	Target Neighborhood Hits	209	Shared Neighborhood Hits	34
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

DOK1_HUMAN
NC score	0.029173 (rank : 942)	θ value	6.88961 (rank : 502)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

TTBK1_HUMAN
NC score	0.028914 (rank : 943)	θ value	6.88961 (rank : 536)
Query Neighborhood Hits	593	Target Neighborhood Hits	1058	Shared Neighborhood Hits	118
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

CENPC_HUMAN
NC score	0.028852 (rank : 944)	θ value	1.81305 (rank : 311)
Query Neighborhood Hits	593	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

BCL3_MOUSE
NC score	0.028696 (rank : 945)	θ value	0.47712 (rank : 207)
Query Neighborhood Hits	593	Target Neighborhood Hits	388	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

DHX57_MOUSE
NC score	0.028694 (rank : 946)	θ value	0.163984 (rank : 155)
Query Neighborhood Hits	593	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ZN414_MOUSE
NC score	0.028592 (rank : 947)	θ value	5.27518 (rank : 484)
Query Neighborhood Hits	593	Target Neighborhood Hits	473	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

THAP7_HUMAN
NC score	0.028134 (rank : 948)	θ value	5.27518 (rank : 474)
Query Neighborhood Hits	593	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

NCTR2_HUMAN
NC score	0.028096 (rank : 949)	θ value	5.27518 (rank : 459)
Query Neighborhood Hits	593	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

TAF6L_MOUSE
NC score	0.028037 (rank : 950)	θ value	8.99809 (rank : 587)
Query Neighborhood Hits	593	Target Neighborhood Hits	146	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

DGKH_HUMAN
NC score	0.027970 (rank : 951)	θ value	2.36792 (rank : 345)
Query Neighborhood Hits	593	Target Neighborhood Hits	255	Shared Neighborhood Hits	26
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

MYPN_HUMAN
NC score	0.027723 (rank : 952)	θ value	6.88961 (rank : 519)
Query Neighborhood Hits	593	Target Neighborhood Hits	418	Shared Neighborhood Hits	58
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

TLN1_HUMAN
NC score	0.027274 (rank : 953)	θ value	3.0926 (rank : 394)
Query Neighborhood Hits	593	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TOP1_MOUSE
NC score	0.026937 (rank : 954)	θ value	4.03905 (rank : 431)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

MAN1_HUMAN
NC score	0.026901 (rank : 955)	θ value	1.81305 (rank : 323)
Query Neighborhood Hits	593	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2U8, Q9NT47, Q9NYA5	Gene names	LEMD3, MAN1
Domain Architecture
Description	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3).

TM55B_MOUSE
NC score	0.026856 (rank : 956)	θ value	1.38821 (rank : 302)
Query Neighborhood Hits	593	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

ZN217_HUMAN
NC score	0.026624 (rank : 957)	θ value	0.00175202 (rank : 55)
Query Neighborhood Hits	593	Target Neighborhood Hits	905	Shared Neighborhood Hits	85
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

GGA2_HUMAN
NC score	0.026363 (rank : 958)	θ value	1.81305 (rank : 315)
Query Neighborhood Hits	593	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

CYH4_MOUSE
NC score	0.026330 (rank : 959)	θ value	6.88961 (rank : 498)
Query Neighborhood Hits	593	Target Neighborhood Hits	134	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

ARNT_MOUSE
NC score	0.025865 (rank : 960)	θ value	6.88961 (rank : 487)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	38
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

CSPG2_MOUSE
NC score	0.025303 (rank : 961)	θ value	6.88961 (rank : 497)
Query Neighborhood Hits	593	Target Neighborhood Hits	711	Shared Neighborhood Hits	60
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MYH14_MOUSE
NC score	0.024972 (rank : 962)	θ value	0.0961366 (rank : 138)
Query Neighborhood Hits	593	Target Neighborhood Hits	1225	Shared Neighborhood Hits	61
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NFIP2_HUMAN
NC score	0.024749 (rank : 963)	θ value	4.03905 (rank : 414)
Query Neighborhood Hits	593	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

CTGE6_HUMAN
NC score	0.024678 (rank : 964)	θ value	1.38821 (rank : 283)
Query Neighborhood Hits	593	Target Neighborhood Hits	650	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

GGA2_MOUSE
NC score	0.024654 (rank : 965)	θ value	0.62314 (rank : 222)
Query Neighborhood Hits	593	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

FOXH1_HUMAN
NC score	0.024415 (rank : 966)	θ value	1.38821 (rank : 285)
Query Neighborhood Hits	593	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

KMHN1_HUMAN
NC score	0.024362 (rank : 967)	θ value	0.0330416 (rank : 104)
Query Neighborhood Hits	593	Target Neighborhood Hits	950	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

HPS4_MOUSE
NC score	0.023898 (rank : 968)	θ value	8.99809 (rank : 562)
Query Neighborhood Hits	593	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

PP1R8_MOUSE
NC score	0.023555 (rank : 969)	θ value	4.03905 (rank : 419)
Query Neighborhood Hits	593	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

RAI14_MOUSE
NC score	0.023352 (rank : 970)	θ value	4.03905 (rank : 424)
Query Neighborhood Hits	593	Target Neighborhood Hits	1505	Shared Neighborhood Hits	88
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CAC1B_MOUSE
NC score	0.023191 (rank : 971)	θ value	5.27518 (rank : 436)
Query Neighborhood Hits	593	Target Neighborhood Hits	351	Shared Neighborhood Hits	66
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

NDF1_HUMAN
NC score	0.023148 (rank : 972)	θ value	3.0926 (rank : 384)
Query Neighborhood Hits	593	Target Neighborhood Hits	186	Shared Neighborhood Hits	29
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

MYH13_HUMAN
NC score	0.023119 (rank : 973)	θ value	0.0431538 (rank : 116)
Query Neighborhood Hits	593	Target Neighborhood Hits	1504	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

TLN2_MOUSE
NC score	0.023019 (rank : 974)	θ value	3.0926 (rank : 396)
Query Neighborhood Hits	593	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.022934 (rank : 975)	θ value	3.0926 (rank : 395)
Query Neighborhood Hits	593	Target Neighborhood Hits	157	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TOP1_HUMAN
NC score	0.022901 (rank : 976)	θ value	6.88961 (rank : 535)
Query Neighborhood Hits	593	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

BORG1_HUMAN
NC score	0.022796 (rank : 977)	θ value	8.99809 (rank : 544)
Query Neighborhood Hits	593	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

NU155_HUMAN
NC score	0.022583 (rank : 978)	θ value	1.81305 (rank : 329)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	O75694, Q9UBE9, Q9UFL5	Gene names	NUP155, KIAA0791
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

RABE1_HUMAN
NC score	0.022471 (rank : 979)	θ value	0.813845 (rank : 249)
Query Neighborhood Hits	593	Target Neighborhood Hits	1104	Shared Neighborhood Hits	59
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CHD5_HUMAN
NC score	0.022138 (rank : 980)	θ value	1.38821 (rank : 278)
Query Neighborhood Hits	593	Target Neighborhood Hits	349	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

PP1R8_HUMAN
NC score	0.022031 (rank : 981)	θ value	5.27518 (rank : 463)
Query Neighborhood Hits	593	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

BORG1_MOUSE
NC score	0.022008 (rank : 982)	θ value	4.03905 (rank : 405)
Query Neighborhood Hits	593	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

TAF9B_HUMAN
NC score	0.021928 (rank : 983)	θ value	8.99809 (rank : 588)
Query Neighborhood Hits	593	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

STAT6_MOUSE
NC score	0.021635 (rank : 984)	θ value	8.99809 (rank : 586)
Query Neighborhood Hits	593	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

ATS14_HUMAN
NC score	0.021627 (rank : 985)	θ value	1.06291 (rank : 256)
Query Neighborhood Hits	593	Target Neighborhood Hits	382	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

KLF17_HUMAN
NC score	0.021603 (rank : 986)	θ value	0.62314 (rank : 224)
Query Neighborhood Hits	593	Target Neighborhood Hits	882	Shared Neighborhood Hits	96
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

TLN1_MOUSE
NC score	0.021592 (rank : 987)	θ value	8.99809 (rank : 590)
Query Neighborhood Hits	593	Target Neighborhood Hits	213	Shared Neighborhood Hits	22
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

P73L_HUMAN
NC score	0.021517 (rank : 988)	θ value	3.0926 (rank : 386)
Query Neighborhood Hits	593	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

STON1_HUMAN
NC score	0.021502 (rank : 989)	θ value	4.03905 (rank : 428)
Query Neighborhood Hits	593	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

K1219_HUMAN
NC score	0.021501 (rank : 990)	θ value	8.99809 (rank : 567)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

K1219_MOUSE
NC score	0.021439 (rank : 991)	θ value	8.99809 (rank : 568)
Query Neighborhood Hits	593	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

CLSPN_HUMAN
NC score	0.021311 (rank : 992)	θ value	5.27518 (rank : 442)
Query Neighborhood Hits	593	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

DCC_HUMAN
NC score	0.021250 (rank : 993)	θ value	8.99809 (rank : 553)
Query Neighborhood Hits	593	Target Neighborhood Hits	583	Shared Neighborhood Hits	42
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

XCL2_HUMAN
NC score	0.021064 (rank : 994)	θ value	2.36792 (rank : 369)
Query Neighborhood Hits	593	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBD3	Gene names	XCL2, SCYC2
Domain Architecture
Description	Cytokine SCM-1 beta precursor (XCL2) (XC chemokine ligand 2).

CS029_MOUSE
NC score	0.020844 (rank : 995)	θ value	8.99809 (rank : 549)
Query Neighborhood Hits	593	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

SCAP_HUMAN
NC score	0.020721 (rank : 996)	θ value	5.27518 (rank : 467)
Query Neighborhood Hits	593	Target Neighborhood Hits	368	Shared Neighborhood Hits	46
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

TCF8_HUMAN
NC score	0.020688 (rank : 997)	θ value	0.00509761 (rank : 67)
Query Neighborhood Hits	593	Target Neighborhood Hits	1057	Shared Neighborhood Hits	63
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

EGR1_MOUSE
NC score	0.020504 (rank : 998)	θ value	0.365318 (rank : 190)
Query Neighborhood Hits	593	Target Neighborhood Hits	816	Shared Neighborhood Hits	81
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

ZF106_MOUSE
NC score	0.020389 (rank : 999)	θ value	5.27518 (rank : 481)
Query Neighborhood Hits	593	Target Neighborhood Hits	472	Shared Neighborhood Hits	53
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

STON2_HUMAN
NC score	0.020230 (rank : 1000)	θ value	5.27518 (rank : 470)
Query Neighborhood Hits	593	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

PTN22_MOUSE
NC score	0.019277 (rank : 1001)	θ value	0.813845 (rank : 248)
Query Neighborhood Hits	593	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

RAI14_HUMAN
NC score	0.019275 (rank : 1002)	θ value	4.03905 (rank : 423)
Query Neighborhood Hits	593	Target Neighborhood Hits	1367	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

MYH7_HUMAN
NC score	0.019090 (rank : 1003)	θ value	5.27518 (rank : 456)
Query Neighborhood Hits	593	Target Neighborhood Hits	1559	Shared Neighborhood Hits	68
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NUCL_HUMAN
NC score	0.018984 (rank : 1004)	θ value	3.0926 (rank : 385)
Query Neighborhood Hits	593	Target Neighborhood Hits	415	Shared Neighborhood Hits	31
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

MYH6_HUMAN
NC score	0.018945 (rank : 1005)	θ value	6.88961 (rank : 518)
Query Neighborhood Hits	593	Target Neighborhood Hits	1426	Shared Neighborhood Hits	62
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

DAF1_MOUSE
NC score	0.018922 (rank : 1006)	θ value	4.03905 (rank : 408)
Query Neighborhood Hits	593	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

HCN1_HUMAN
NC score	0.018458 (rank : 1007)	θ value	1.06291 (rank : 263)
Query Neighborhood Hits	593	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

FRAS1_MOUSE
NC score	0.018452 (rank : 1008)	θ value	1.81305 (rank : 313)
Query Neighborhood Hits	593	Target Neighborhood Hits	747	Shared Neighborhood Hits	23
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

E2F1_HUMAN
NC score	0.018259 (rank : 1009)	θ value	2.36792 (rank : 346)
Query Neighborhood Hits	593	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

FRAS1_HUMAN
NC score	0.018235 (rank : 1010)	θ value	0.279714 (rank : 176)
Query Neighborhood Hits	593	Target Neighborhood Hits	759	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

UROL1_MOUSE
NC score	0.018073 (rank : 1011)	θ value	2.36792 (rank : 368)
Query Neighborhood Hits	593	Target Neighborhood Hits	235	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

HMMR_MOUSE
NC score	0.017879 (rank : 1012)	θ value	2.36792 (rank : 350)
Query Neighborhood Hits	593	Target Neighborhood Hits	1178	Shared Neighborhood Hits	53
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CENG3_MOUSE
NC score	0.017639 (rank : 1013)	θ value	6.88961 (rank : 496)
Query Neighborhood Hits	593	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

RUNX1_HUMAN
NC score	0.017528 (rank : 1014)	θ value	5.27518 (rank : 465)
Query Neighborhood Hits	593	Target Neighborhood Hits	94	Shared Neighborhood Hits	22
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

CENG3_HUMAN
NC score	0.017522 (rank : 1015)	θ value	6.88961 (rank : 495)
Query Neighborhood Hits	593	Target Neighborhood Hits	455	Shared Neighborhood Hits	28
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ULK1_MOUSE
NC score	0.017501 (rank : 1016)	θ value	0.0563607 (rank : 124)
Query Neighborhood Hits	593	Target Neighborhood Hits	1214	Shared Neighborhood Hits	118
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

KIF1B_MOUSE
NC score	0.017354 (rank : 1017)	θ value	0.279714 (rank : 178)
Query Neighborhood Hits	593	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

GLIS3_MOUSE
NC score	0.017177 (rank : 1018)	θ value	2.36792 (rank : 348)
Query Neighborhood Hits	593	Target Neighborhood Hits	861	Shared Neighborhood Hits	90
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

KCNQ2_MOUSE
NC score	0.017117 (rank : 1019)	θ value	0.279714 (rank : 177)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

GLI2_HUMAN
NC score	0.017097 (rank : 1020)	θ value	1.38821 (rank : 287)
Query Neighborhood Hits	593	Target Neighborhood Hits	971	Shared Neighborhood Hits	103
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GATA6_MOUSE
NC score	0.016775 (rank : 1021)	θ value	1.06291 (rank : 260)
Query Neighborhood Hits	593	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	Q61169, P97729, Q9QZK3	Gene names	Gata6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

XCL1_HUMAN
NC score	0.016736 (rank : 1022)	θ value	5.27518 (rank : 480)
Query Neighborhood Hits	593	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P47992, Q52MA8	Gene names	XCL1, LTN, SCYC1
Domain Architecture
Description	Lymphotactin precursor (XCL1) (Cytokine SCM-1) (ATAC) (Lymphotaxin) (SCM-1-alpha) (Small inducible cytokine C1) (XC chemokine ligand 1).

NID2_HUMAN
NC score	0.016363 (rank : 1023)	θ value	1.81305 (rank : 328)
Query Neighborhood Hits	593	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

JHD2A_HUMAN
NC score	0.016277 (rank : 1024)	θ value	8.99809 (rank : 565)
Query Neighborhood Hits	593	Target Neighborhood Hits	118	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

AHI1_HUMAN
NC score	0.016073 (rank : 1025)	θ value	6.88961 (rank : 486)
Query Neighborhood Hits	593	Target Neighborhood Hits	537	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

IGHD_HUMAN
NC score	0.015987 (rank : 1026)	θ value	1.38821 (rank : 289)
Query Neighborhood Hits	593	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	P01880	Gene names	IGHD
Domain Architecture	No domain graphic available
Description	Ig delta chain C region.

TLE4_HUMAN
NC score	0.015704 (rank : 1027)	θ value	5.27518 (rank : 475)
Query Neighborhood Hits	593	Target Neighborhood Hits	477	Shared Neighborhood Hits	57
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

KIF1B_HUMAN
NC score	0.015669 (rank : 1028)	θ value	1.81305 (rank : 321)
Query Neighborhood Hits	593	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	O60333, Q96Q94, Q9BV80, Q9P280	Gene names	KIF1B, KIAA0591, KIAA1448
Domain Architecture
Description	Kinesin-like protein KIF1B (Klp).

TLE4_MOUSE
NC score	0.015624 (rank : 1029)	θ value	5.27518 (rank : 476)
Query Neighborhood Hits	593	Target Neighborhood Hits	482	Shared Neighborhood Hits	58
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

USH2A_MOUSE
NC score	0.015613 (rank : 1030)	θ value	5.27518 (rank : 479)
Query Neighborhood Hits	593	Target Neighborhood Hits	626	Shared Neighborhood Hits	32
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

GCM2_HUMAN
NC score	0.015552 (rank : 1031)	θ value	8.99809 (rank : 559)
Query Neighborhood Hits	593	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

MYLK_MOUSE
NC score	0.015260 (rank : 1032)	θ value	0.813845 (rank : 246)
Query Neighborhood Hits	593	Target Neighborhood Hits	1489	Shared Neighborhood Hits	99
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ETV1_MOUSE
NC score	0.014866 (rank : 1033)	θ value	6.88961 (rank : 505)
Query Neighborhood Hits	593	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

INSM1_MOUSE
NC score	0.014707 (rank : 1034)	θ value	5.27518 (rank : 451)
Query Neighborhood Hits	593	Target Neighborhood Hits	678	Shared Neighborhood Hits	47
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

ES8L2_HUMAN
NC score	0.014379 (rank : 1035)	θ value	6.88961 (rank : 504)
Query Neighborhood Hits	593	Target Neighborhood Hits	193	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

LAMA5_HUMAN
NC score	0.014131 (rank : 1036)	θ value	6.88961 (rank : 512)
Query Neighborhood Hits	593	Target Neighborhood Hits	976	Shared Neighborhood Hits	61
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

GLI1_HUMAN
NC score	0.014030 (rank : 1037)	θ value	0.813845 (rank : 239)
Query Neighborhood Hits	593	Target Neighborhood Hits	828	Shared Neighborhood Hits	65
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HXB3_HUMAN
NC score	0.014014 (rank : 1038)	θ value	0.813845 (rank : 241)
Query Neighborhood Hits	593	Target Neighborhood Hits	559	Shared Neighborhood Hits	68
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

PSMF1_MOUSE
NC score	0.013988 (rank : 1039)	θ value	8.99809 (rank : 578)
Query Neighborhood Hits	593	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

PTPRN_MOUSE
NC score	0.013838 (rank : 1040)	θ value	3.0926 (rank : 388)
Query Neighborhood Hits	593	Target Neighborhood Hits	240	Shared Neighborhood Hits	51
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

ZN142_HUMAN
NC score	0.013772 (rank : 1041)	θ value	1.06291 (rank : 271)
Query Neighborhood Hits	593	Target Neighborhood Hits	1007	Shared Neighborhood Hits	104
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

SP5_MOUSE
NC score	0.013515 (rank : 1042)	θ value	6.88961 (rank : 532)
Query Neighborhood Hits	593	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

MAST1_HUMAN
NC score	0.013413 (rank : 1043)	θ value	6.88961 (rank : 516)
Query Neighborhood Hits	593	Target Neighborhood Hits	1146	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SRPK1_HUMAN
NC score	0.013407 (rank : 1044)	θ value	4.03905 (rank : 426)
Query Neighborhood Hits	593	Target Neighborhood Hits	706	Shared Neighborhood Hits	60
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

P3H1_HUMAN
NC score	0.013026 (rank : 1045)	θ value	1.38821 (rank : 297)
Query Neighborhood Hits	593	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

LAMC3_HUMAN
NC score	0.012748 (rank : 1046)	θ value	4.03905 (rank : 412)
Query Neighborhood Hits	593	Target Neighborhood Hits	588	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

IRTF_HUMAN
NC score	0.012686 (rank : 1047)	θ value	6.88961 (rank : 510)
Query Neighborhood Hits	593	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

PRD16_HUMAN
NC score	0.012601 (rank : 1048)	θ value	0.47712 (rank : 214)
Query Neighborhood Hits	593	Target Neighborhood Hits	832	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

EGR3_MOUSE
NC score	0.012454 (rank : 1049)	θ value	0.47712 (rank : 210)
Query Neighborhood Hits	593	Target Neighborhood Hits	747	Shared Neighborhood Hits	44
SwissProt Accessions	P43300, Q9R276	Gene names	Egr3, Egr-3
Domain Architecture
Description	Early growth response protein 3 (EGR-3).

EGR3_HUMAN
NC score	0.012434 (rank : 1050)	θ value	0.47712 (rank : 209)
Query Neighborhood Hits	593	Target Neighborhood Hits	746	Shared Neighborhood Hits	44
SwissProt Accessions	Q06889	Gene names	EGR3, PILOT
Domain Architecture	No domain graphic available
Description	Early growth response protein 3 (EGR-3) (Zinc finger protein pilot).

EVI1_HUMAN
NC score	0.012397 (rank : 1051)	θ value	0.163984 (rank : 156)
Query Neighborhood Hits	593	Target Neighborhood Hits	924	Shared Neighborhood Hits	61
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

SART3_MOUSE
NC score	0.012291 (rank : 1052)	θ value	6.88961 (rank : 528)
Query Neighborhood Hits	593	Target Neighborhood Hits	341	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

FAT2_HUMAN
NC score	0.012023 (rank : 1053)	θ value	0.21417 (rank : 169)
Query Neighborhood Hits	593	Target Neighborhood Hits	507	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

SART3_HUMAN
NC score	0.011759 (rank : 1054)	θ value	6.88961 (rank : 527)
Query Neighborhood Hits	593	Target Neighborhood Hits	301	Shared Neighborhood Hits	22
SwissProt Accessions	Q15020, Q58F06, Q8IUS1, Q96J95	Gene names	SART3, KIAA0156, TIP110
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (hSART-3) (Tat-interacting protein of 110 kDa) (Tip110).

DDX20_MOUSE
NC score	0.011003 (rank : 1055)	θ value	0.47712 (rank : 208)
Query Neighborhood Hits	593	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

MARE3_HUMAN
NC score	0.010962 (rank : 1056)	θ value	6.88961 (rank : 514)
Query Neighborhood Hits	593	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPY8, O00265, Q6FI15, Q9BZP7, Q9BZP8	Gene names	MAPRE3
Domain Architecture
Description	Microtubule-associated protein RP/EB family member 3 (End-binding protein 3) (EB3) (EB1 protein family member 3) (EBF3) (RP3).

SNTB2_MOUSE
NC score	0.010778 (rank : 1057)	θ value	8.99809 (rank : 585)
Query Neighborhood Hits	593	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

MARE3_MOUSE
NC score	0.010776 (rank : 1058)	θ value	6.88961 (rank : 515)
Query Neighborhood Hits	593	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PER3, Q61167	Gene names	Mapre3
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein RP/EB family member 3 (End-binding protein 3) (EB3) (EB1 protein family member 3) (EBF3) (RP3).

PMS2_MOUSE
NC score	0.010712 (rank : 1059)	θ value	6.88961 (rank : 524)
Query Neighborhood Hits	593	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

MRCKB_HUMAN
NC score	0.010403 (rank : 1060)	θ value	2.36792 (rank : 358)
Query Neighborhood Hits	593	Target Neighborhood Hits	2239	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ZN198_HUMAN
NC score	0.010310 (rank : 1061)	θ value	5.27518 (rank : 482)
Query Neighborhood Hits	593	Target Neighborhood Hits	128	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

ITF2_MOUSE
NC score	0.009803 (rank : 1062)	θ value	8.99809 (rank : 564)
Query Neighborhood Hits	593	Target Neighborhood Hits	154	Shared Neighborhood Hits	16
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

SDK1_HUMAN
NC score	0.009519 (rank : 1063)	θ value	6.88961 (rank : 529)
Query Neighborhood Hits	593	Target Neighborhood Hits	511	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TOP2B_HUMAN
NC score	0.009498 (rank : 1064)	θ value	8.99809 (rank : 591)
Query Neighborhood Hits	593	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

PTN4_HUMAN
NC score	0.009242 (rank : 1065)	θ value	5.27518 (rank : 464)
Query Neighborhood Hits	593	Target Neighborhood Hits	303	Shared Neighborhood Hits	35
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SDK1_MOUSE
NC score	0.008761 (rank : 1066)	θ value	6.88961 (rank : 530)
Query Neighborhood Hits	593	Target Neighborhood Hits	495	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ANC1_HUMAN
NC score	0.008730 (rank : 1067)	θ value	8.99809 (rank : 541)
Query Neighborhood Hits	593	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

BCL6_MOUSE
NC score	0.008636 (rank : 1068)	θ value	4.03905 (rank : 404)
Query Neighborhood Hits	593	Target Neighborhood Hits	913	Shared Neighborhood Hits	69
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

PAPOG_HUMAN
NC score	0.008593 (rank : 1069)	θ value	8.99809 (rank : 575)
Query Neighborhood Hits	593	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

M3K14_MOUSE
NC score	0.008456 (rank : 1070)	θ value	2.36792 (rank : 355)
Query Neighborhood Hits	593	Target Neighborhood Hits	889	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

JHD1A_HUMAN
NC score	0.008379 (rank : 1071)	θ value	5.27518 (rank : 453)
Query Neighborhood Hits	593	Target Neighborhood Hits	133	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

CDC20_HUMAN
NC score	0.008331 (rank : 1072)	θ value	4.03905 (rank : 407)
Query Neighborhood Hits	593	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

MARK2_HUMAN
NC score	0.008090 (rank : 1073)	θ value	1.81305 (rank : 324)
Query Neighborhood Hits	593	Target Neighborhood Hits	1056	Shared Neighborhood Hits	75
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

TGIF_MOUSE
NC score	0.007939 (rank : 1074)	θ value	6.88961 (rank : 534)
Query Neighborhood Hits	593	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	P70284, Q921F9, Q99JS3	Gene names	Tgif
Domain Architecture
Description	5'-TG-3'-interacting factor (Homeobox protein TGIF).

BCL6_HUMAN
NC score	0.007888 (rank : 1075)	θ value	6.88961 (rank : 493)
Query Neighborhood Hits	593	Target Neighborhood Hits	922	Shared Neighborhood Hits	63
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

SEM6A_MOUSE
NC score	0.007765 (rank : 1076)	θ value	3.0926 (rank : 391)
Query Neighborhood Hits	593	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

PCD12_MOUSE
NC score	0.007512 (rank : 1077)	θ value	0.0961366 (rank : 139)
Query Neighborhood Hits	593	Target Neighborhood Hits	199	Shared Neighborhood Hits	15
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

ZN688_HUMAN
NC score	0.007235 (rank : 1078)	θ value	1.81305 (rank : 336)
Query Neighborhood Hits	593	Target Neighborhood Hits	873	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

SEM6A_HUMAN
NC score	0.006976 (rank : 1079)	θ value	3.0926 (rank : 390)
Query Neighborhood Hits	593	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

P210L_HUMAN
NC score	0.006759 (rank : 1080)	θ value	6.88961 (rank : 521)
Query Neighborhood Hits	593	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

CDC20_MOUSE
NC score	0.006670 (rank : 1081)	θ value	5.27518 (rank : 439)
Query Neighborhood Hits	593	Target Neighborhood Hits	325	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

IC1_MOUSE
NC score	0.006319 (rank : 1082)	θ value	6.88961 (rank : 509)
Query Neighborhood Hits	593	Target Neighborhood Hits	164	Shared Neighborhood Hits	22
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

ABCA7_HUMAN
NC score	0.006176 (rank : 1083)	θ value	1.81305 (rank : 307)
Query Neighborhood Hits	593	Target Neighborhood Hits	144	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

PKN3_MOUSE
NC score	0.006063 (rank : 1084)	θ value	0.365318 (rank : 199)
Query Neighborhood Hits	593	Target Neighborhood Hits	1009	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

ITCH_HUMAN
NC score	0.006017 (rank : 1085)	θ value	8.99809 (rank : 563)
Query Neighborhood Hits	593	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

PTN14_HUMAN
NC score	0.005670 (rank : 1086)	θ value	8.99809 (rank : 579)
Query Neighborhood Hits	593	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

M3K9_HUMAN
NC score	0.005618 (rank : 1087)	θ value	8.99809 (rank : 570)
Query Neighborhood Hits	593	Target Neighborhood Hits	1123	Shared Neighborhood Hits	76
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

OSBL5_MOUSE
NC score	0.005074 (rank : 1088)	θ value	8.99809 (rank : 573)
Query Neighborhood Hits	593	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

PTN14_MOUSE
NC score	0.004786 (rank : 1089)	θ value	8.99809 (rank : 580)
Query Neighborhood Hits	593	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PRS10_HUMAN
NC score	0.004696 (rank : 1090)	θ value	4.03905 (rank : 421)
Query Neighborhood Hits	593	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.004696 (rank : 1091)	θ value	4.03905 (rank : 422)
Query Neighborhood Hits	593	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

ZBT16_HUMAN
NC score	0.004138 (rank : 1092)	θ value	3.0926 (rank : 402)
Query Neighborhood Hits	593	Target Neighborhood Hits	1010	Shared Neighborhood Hits	65
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ATS4_HUMAN
NC score	0.003936 (rank : 1093)	θ value	6.88961 (rank : 490)
Query Neighborhood Hits	593	Target Neighborhood Hits	138	Shared Neighborhood Hits	6
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

DUET_HUMAN
NC score	0.003922 (rank : 1094)	θ value	8.99809 (rank : 556)
Query Neighborhood Hits	593	Target Neighborhood Hits	1220	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

BACH2_MOUSE
NC score	0.003823 (rank : 1095)	θ value	6.88961 (rank : 491)
Query Neighborhood Hits	593	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

ZN575_MOUSE
NC score	0.003754 (rank : 1096)	θ value	8.99809 (rank : 593)
Query Neighborhood Hits	593	Target Neighborhood Hits	715	Shared Neighborhood Hits	35
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

MTR1L_HUMAN
NC score	0.002965 (rank : 1097)	θ value	8.99809 (rank : 571)
Query Neighborhood Hits	593	Target Neighborhood Hits	1180	Shared Neighborhood Hits	77
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

HXD1_MOUSE
NC score	0.002531 (rank : 1098)	θ value	2.36792 (rank : 353)
Query Neighborhood Hits	593	Target Neighborhood Hits	381	Shared Neighborhood Hits	15
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

ZN605_HUMAN
NC score	0.001838 (rank : 1099)	θ value	1.38821 (rank : 306)
Query Neighborhood Hits	593	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q86T29, Q86T91	Gene names	ZNF605
Domain Architecture	No domain graphic available
Description	Zinc finger protein 605.

TRI17_MOUSE
NC score	0.001829 (rank : 1100)	θ value	5.27518 (rank : 477)
Query Neighborhood Hits	593	Target Neighborhood Hits	620	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

CXA1_MOUSE
NC score	0.000972 (rank : 1101)	θ value	8.99809 (rank : 551)
Query Neighborhood Hits	593	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P23242	Gene names	Gja1, Cxn-43
Domain Architecture
Description	Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein).

DLX4_MOUSE
NC score	0.000829 (rank : 1102)	θ value	6.88961 (rank : 501)
Query Neighborhood Hits	593	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

LRTM4_HUMAN
NC score	0.000117 (rank : 1103)	θ value	2.36792 (rank : 354)
Query Neighborhood Hits	593	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VH4	Gene names	LRRTM4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

E2AK4_MOUSE
NC score	-0.000044 (rank : 1104)	θ value	6.88961 (rank : 503)
Query Neighborhood Hits	593	Target Neighborhood Hits	984	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

M3K4_HUMAN
NC score	-0.001245 (rank : 1105)	θ value	8.99809 (rank : 569)
Query Neighborhood Hits	593	Target Neighborhood Hits	911	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

DCAK1_MOUSE
NC score	-0.001816 (rank : 1106)	θ value	6.88961 (rank : 500)
Query Neighborhood Hits	593	Target Neighborhood Hits	867	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).