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Network neighborhood for query Sequence : DOCK4_MOUSE

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DOCK4_MOUSE
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DOCK1_HUMAN
θ value	0 (rank : 1)	NC score	0.936070 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	191	Shared Neighborhood Hits	35
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOCK2_HUMAN
θ value	0 (rank : 2)	NC score	0.955973 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK2_MOUSE
θ value	0 (rank : 3)	NC score	0.953261 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK3_HUMAN
θ value	0 (rank : 4)	NC score	0.978150 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	0 (rank : 5)	NC score	0.977041 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK4_HUMAN
θ value	0 (rank : 6)	NC score	0.995033 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	237	Shared Neighborhood Hits	179
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOC10_HUMAN
θ value	9.90251e-15 (rank : 8)	NC score	0.456588 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK8_HUMAN
θ value	4.59992e-12 (rank : 9)	NC score	0.410306 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK9_MOUSE
θ value	4.59992e-12 (rank : 10)	NC score	0.417854 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK8_MOUSE
θ value	2.28291e-11 (rank : 11)	NC score	0.418646 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK9_HUMAN
θ value	2.28291e-11 (rank : 12)	NC score	0.414501 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK7_HUMAN
θ value	2.52405e-10 (rank : 13)	NC score	0.404924 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK6_HUMAN
θ value	1.63604e-09 (rank : 14)	NC score	0.390905 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DNMBP_HUMAN
θ value	0.00228821 (rank : 15)	NC score	0.111291 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	413	Shared Neighborhood Hits	34
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

MLL3_MOUSE
θ value	0.00869519 (rank : 16)	NC score	0.053719 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	1399	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SN1L1_HUMAN
θ value	0.0113563 (rank : 17)	NC score	0.007187 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	911	Shared Neighborhood Hits	22
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

TGON2_HUMAN
θ value	0.0113563 (rank : 18)	NC score	0.050372 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	1037	Shared Neighborhood Hits	70
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ENL_HUMAN
θ value	0.0193708 (rank : 19)	NC score	0.079352 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

K1802_MOUSE
θ value	0.0193708 (rank : 20)	NC score	0.051458 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	1596	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ACINU_MOUSE
θ value	0.0252991 (rank : 21)	NC score	0.067808 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	712	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DNMBP_MOUSE
θ value	0.0252991 (rank : 22)	NC score	0.104636 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	435	Shared Neighborhood Hits	37
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SRRM1_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.088644 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	966	Shared Neighborhood Hits	89
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

JHD2B_HUMAN
θ value	0.0330416 (rank : 24)	NC score	0.038959 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

NFH_MOUSE
θ value	0.0431538 (rank : 25)	NC score	0.037098 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	2247	Shared Neighborhood Hits	109
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SRRM1_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.086562 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PCLO_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.052254 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	2046	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PO2F2_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.026170 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	379	Shared Neighborhood Hits	16
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

ENAM_MOUSE
θ value	0.0961366 (rank : 29)	NC score	0.058434 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	229	Shared Neighborhood Hits	29
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

MUC1_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.042131 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	975	Shared Neighborhood Hits	78
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NFM_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.017842 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	1328	Shared Neighborhood Hits	61
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

ST5_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.032615 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

LRP10_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.036683 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

SRBS1_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.088269 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	396	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ZIMP7_MOUSE
θ value	0.125558 (rank : 35)	NC score	0.045736 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	566	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN292_HUMAN
θ value	0.125558 (rank : 36)	NC score	0.034086 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	918	Shared Neighborhood Hits	22
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

HRX_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.047287 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	825	Shared Neighborhood Hits	59
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MDC1_MOUSE
θ value	0.21417 (rank : 38)	NC score	0.056767 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	998	Shared Neighborhood Hits	88
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SYNJ1_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.045899 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	516	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

3BP1_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.037939 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	238	Shared Neighborhood Hits	30
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

LRP10_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.035324 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NCOA6_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.065695 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TROAP_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.048151 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

CSKI2_HUMAN
θ value	0.365318 (rank : 44)	NC score	0.022663 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	747	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MLL3_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.054088 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	1644	Shared Neighborhood Hits	102
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SELV_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.086259 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

HCLS1_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.068740 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	358	Shared Neighborhood Hits	50
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCN4_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.020904 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	284	Shared Neighborhood Hits	32
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

SELPL_MOUSE
θ value	0.47712 (rank : 49)	NC score	0.049028 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	588	Shared Neighborhood Hits	60
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRBS1_MOUSE
θ value	0.47712 (rank : 50)	NC score	0.082141 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYTL2_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.023586 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

ARI5B_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.037911 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	158	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

JHD2B_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.026919 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

MBD6_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.066182 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	349	Shared Neighborhood Hits	45
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PTN23_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.028877 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	646	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SI1L1_MOUSE
θ value	0.62314 (rank : 56)	NC score	0.028670 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	189	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SRRM2_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.055589 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	1296	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

VINEX_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.091408 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

BPA1_MOUSE
θ value	0.813845 (rank : 59)	NC score	0.009631 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	1477	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HEAT1_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.043197 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

MYT1L_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.019573 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	461	Shared Neighborhood Hits	13
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

NACAM_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.053209 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	1866	Shared Neighborhood Hits	120
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NRG2_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.024310 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SON_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.040556 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	1568	Shared Neighborhood Hits	107
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

VINEX_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.091230 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

3BP1_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.042789 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	376	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

DIAP1_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.023889 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	784	Shared Neighborhood Hits	39
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

FOXR1_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.019417 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PIV2, Q86UT9, Q8IXX2	Gene names	FOXR1, DLNB13, FOXN5
Domain Architecture	No domain graphic available
Description	Forkhead box protein R1 (Forkhead box protein N5).

GRIN1_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.037109 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	681	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

OGFR_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.035737 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	1582	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RFIP1_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.032298 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

ZBTB4_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.007135 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	926	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

AMOT_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.028046 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	712	Shared Neighborhood Hits	41
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

BLNK_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.039891 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	296	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

IC1_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.013252 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

M3K10_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.008637 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	1071	Shared Neighborhood Hits	35
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PTPRN_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.013917 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

RIMS1_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.026493 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	437	Shared Neighborhood Hits	28
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SON_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.051061 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	957	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

USH1C_MOUSE
θ value	1.38821 (rank : 80)	NC score	0.018076 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	557	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

AFF3_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.028117 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	27
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

CAC1D_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.010487 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CNOT4_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.028922 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.034666 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	277	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

ERRFI_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.032497 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

IL6RA_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.014967 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

NELFA_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.057579 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	195	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

RAPH1_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.052649 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	593	Shared Neighborhood Hits	65
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RD23A_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.031551 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	P54725	Gene names	RAD23A
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (hHR23A).

RD23A_MOUSE
θ value	1.81305 (rank : 90)	NC score	0.030075 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

RTN4_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.029242 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	341	Shared Neighborhood Hits	36
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

WNK3_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.003102 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	948	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

ZC3H3_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.026275 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZN516_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.005887 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	1197	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

B4GN4_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.023617 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BUB1_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.013020 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CABYR_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.031073 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

COFA1_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.017179 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

DIDO1_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.031797 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	960	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

LYN_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.011491 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	1023	Shared Neighborhood Hits	33
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

NPAS1_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.014538 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

TENS1_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.028738 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	400	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TULP1_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.021392 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

ZMYM3_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.020039 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZMYM3_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.019488 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

ARI4A_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.023312 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	434	Shared Neighborhood Hits	16
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CAF1B_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.013352 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	385	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CIC_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.035863 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	992	Shared Neighborhood Hits	76
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIZ1_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.029587 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	359	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

FREA_MOUSE
θ value	3.0926 (rank : 110)	NC score	0.015476 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

FXL19_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.019819 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GON4L_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.025645 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	455	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCLS1_MOUSE
θ value	3.0926 (rank : 113)	NC score	0.053790 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

LPHN1_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.008629 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	155	Shared Neighborhood Hits	7
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

MINT_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.029703 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	1291	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NAF1_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.012287 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	852	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCA11_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.014418 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	661	Shared Neighborhood Hits	41
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PO2F2_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.014844 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

SI1L3_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.022191 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	41
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SPN90_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.031845 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPT5H_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.037967 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	436	Shared Neighborhood Hits	47
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.038438 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	437	Shared Neighborhood Hits	49
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRRM2_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.062628 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	1470	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TBCD3_HUMAN
θ value	3.0926 (rank : 124)	NC score	0.017474 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

AB1IP_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.027007 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	213	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ANM8_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.013388 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR22, Q8TBJ8	Gene names	PRMT8, HRMT1L3, HRMT1L4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

ATP7B_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.006854 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q64446	Gene names	Atp7b, Wnd
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein homolog).

CAF1A_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.014929 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	750	Shared Neighborhood Hits	27
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD45_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.015657 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	663	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CDON_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.003443 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	410	Shared Neighborhood Hits	8
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CO8A_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.011316 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

GP158_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.021729 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP1BA_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.012067 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	407	Shared Neighborhood Hits	29
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

HPS4_MOUSE
θ value	4.03905 (rank : 134)	NC score	0.016520 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

IRS2_MOUSE
θ value	4.03905 (rank : 135)	NC score	0.025475 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MDC1_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.057385 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	1446	Shared Neighborhood Hits	101
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MINT_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.033934 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	1514	Shared Neighborhood Hits	89
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OBSCN_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.005431 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	1931	Shared Neighborhood Hits	80
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PRG4_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.050142 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	764	Shared Neighborhood Hits	77
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RUSC2_MOUSE
θ value	4.03905 (rank : 140)	NC score	0.027194 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SYEP_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.016289 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

TARA_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.037122 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

UN13B_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.009346 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CAC1H_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.009707 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	307	Shared Neighborhood Hits	25
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

DC1L2_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.013107 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

IF4G3_HUMAN
θ value	5.27518 (rank : 146)	NC score	0.012469 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	247	Shared Neighborhood Hits	21
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ITSN1_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.039623 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	1669	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

JAG2_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.002187 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	504	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

K1802_HUMAN
θ value	5.27518 (rank : 149)	NC score	0.033280 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	1378	Shared Neighborhood Hits	79
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LYN_HUMAN
θ value	5.27518 (rank : 150)	NC score	0.010648 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	1022	Shared Neighborhood Hits	32
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K9_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.014490 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	1123	Shared Neighborhood Hits	47
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M4K4_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.001717 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	1589	Shared Neighborhood Hits	35
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAMC2_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.012382 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MBD5_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.028193 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MISS_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.034618 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	444	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NCOR2_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.024772 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	790	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NFAC1_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.007639 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NGEF_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.023452 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PCLO_MOUSE
θ value	5.27518 (rank : 159)	NC score	0.041256 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	2275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RIF1_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.015942 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	320	Shared Neighborhood Hits	13
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SI1L1_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.018770 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SMP1L_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.009646 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

TM108_HUMAN
θ value	5.27518 (rank : 163)	NC score	0.032354 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	166	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ZIMP7_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.025737 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	290	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ABL1_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.004140 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	1178	Shared Neighborhood Hits	48
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ARI1B_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.029183 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	567	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CIC_MOUSE
θ value	6.88961 (rank : 167)	NC score	0.034231 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	742	Shared Neighborhood Hits	67
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ012_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.037385 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CSKI1_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.019475 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	997	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUL4B_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.007655 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

GOGA4_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.005487 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	2034	Shared Neighborhood Hits	46
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GRAP_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.037000 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	307	Shared Neighborhood Hits	31
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.036641 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	309	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ITSN1_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.037960 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	1757	Shared Neighborhood Hits	79
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

K0423_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.022754 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

LPP_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.016163 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	775	Shared Neighborhood Hits	65
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LR37B_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.010194 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	392	Shared Neighborhood Hits	26
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

LYAM2_MOUSE
θ value	6.88961 (rank : 178)	NC score	0.003735 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MYO15_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.009839 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	671	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PLXB3_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.006374 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PTN23_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.022395 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	726	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

TDRD4_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.018391 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

TMCC1_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.008221 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	8
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TSH2_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.007956 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

WDHD1_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.007927 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

ANM8_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.009660 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PAK3, Q7M6Z2	Gene names	Prmt8, Hrmt1l4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

CAC1E_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.007154 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CK024_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.030377 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CN037_MOUSE
θ value	8.99809 (rank : 189)	NC score	0.015557 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CRBB3_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.005962 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJU9	Gene names	Crybb3
Domain Architecture
Description	Beta crystallin B3 (Beta-B3-crystallin).

DC1L2_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.010090 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	O43237, Q8TAT3	Gene names	DYNC1LI2, DNCLI2, LIC2
Domain Architecture
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC53/55) (LIC-2).

EPAS1_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.007238 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HXA3_MOUSE
θ value	8.99809 (rank : 193)	NC score	0.005460 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	558	Shared Neighborhood Hits	40
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

KCNC3_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.005152 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	256	Shared Neighborhood Hits	26
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KIRR2_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.004481 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	326	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

LATS1_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.002148 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	1057	Shared Neighborhood Hits	36
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

MILK2_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.017127 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MLL2_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.037932 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	1788	Shared Neighborhood Hits	92
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NEBU_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.025241 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	420	Shared Neighborhood Hits	27
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NMDE3_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.004630 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NOLA1_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.010848 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CY66, Q80X93, Q8C6C5, Q8VDH0	Gene names	Nola1, Gar1
Domain Architecture	No domain graphic available
Description	H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1).

NOTC3_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.001317 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NU153_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.011543 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

PLCB1_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.009016 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	614	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.008543 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	531	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SMRCD_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.003852 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SYNJ1_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.033618 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	498	Shared Neighborhood Hits	60
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TTP_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.014563 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

WIRE_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.043302 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.038411 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

Hits sorted by NC score

DOCK4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_HUMAN
NC score	0.995033 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	237	Shared Neighborhood Hits	179
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK3_HUMAN
NC score	0.978150 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
NC score	0.977041 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK2_HUMAN
NC score	0.955973 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK2_MOUSE
NC score	0.953261 (rank : 6)	θ value	0 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK1_HUMAN
NC score	0.936070 (rank : 7)	θ value	0 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	191	Shared Neighborhood Hits	35
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOC10_HUMAN
NC score	0.456588 (rank : 8)	θ value	9.90251e-15 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK8_MOUSE
NC score	0.418646 (rank : 9)	θ value	2.28291e-11 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK9_MOUSE
NC score	0.417854 (rank : 10)	θ value	4.59992e-12 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
NC score	0.414501 (rank : 11)	θ value	2.28291e-11 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK8_HUMAN
NC score	0.410306 (rank : 12)	θ value	4.59992e-12 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK7_HUMAN
NC score	0.404924 (rank : 13)	θ value	2.52405e-10 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK6_HUMAN
NC score	0.390905 (rank : 14)	θ value	1.63604e-09 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DNMBP_HUMAN
NC score	0.111291 (rank : 15)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	413	Shared Neighborhood Hits	34
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
NC score	0.104636 (rank : 16)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	435	Shared Neighborhood Hits	37
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VINEX_HUMAN
NC score	0.091408 (rank : 17)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
NC score	0.091230 (rank : 18)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRRM1_MOUSE
NC score	0.088644 (rank : 19)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	966	Shared Neighborhood Hits	89
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRBS1_HUMAN
NC score	0.088269 (rank : 20)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	396	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRRM1_HUMAN
NC score	0.086562 (rank : 21)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SELV_HUMAN
NC score	0.086259 (rank : 22)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SRBS1_MOUSE
NC score	0.082141 (rank : 23)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ENL_HUMAN
NC score	0.079352 (rank : 24)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HCLS1_HUMAN
NC score	0.068740 (rank : 25)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	358	Shared Neighborhood Hits	50
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ACINU_MOUSE
NC score	0.067808 (rank : 26)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	712	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MBD6_HUMAN
NC score	0.066182 (rank : 27)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	349	Shared Neighborhood Hits	45
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

NCOA6_HUMAN
NC score	0.065695 (rank : 28)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SRRM2_MOUSE
NC score	0.062628 (rank : 29)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	1470	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ENAM_MOUSE
NC score	0.058434 (rank : 30)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	229	Shared Neighborhood Hits	29
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

NELFA_MOUSE
NC score	0.057579 (rank : 31)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	195	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

MDC1_HUMAN
NC score	0.057385 (rank : 32)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	1446	Shared Neighborhood Hits	101
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
NC score	0.056767 (rank : 33)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	998	Shared Neighborhood Hits	88
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SRRM2_HUMAN
NC score	0.055589 (rank : 34)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	1296	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MLL3_HUMAN
NC score	0.054088 (rank : 35)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	1644	Shared Neighborhood Hits	102
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

HCLS1_MOUSE
NC score	0.053790 (rank : 36)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

MLL3_MOUSE
NC score	0.053719 (rank : 37)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	1399	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NACAM_MOUSE
NC score	0.053209 (rank : 38)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	1866	Shared Neighborhood Hits	120
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RAPH1_HUMAN
NC score	0.052649 (rank : 39)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	593	Shared Neighborhood Hits	65
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PCLO_HUMAN
NC score	0.052254 (rank : 40)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	2046	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

K1802_MOUSE
NC score	0.051458 (rank : 41)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	1596	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SON_MOUSE
NC score	0.051061 (rank : 42)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	957	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TGON2_HUMAN
NC score	0.050372 (rank : 43)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	1037	Shared Neighborhood Hits	70
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PRG4_HUMAN
NC score	0.050142 (rank : 44)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	764	Shared Neighborhood Hits	77
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SELPL_MOUSE
NC score	0.049028 (rank : 45)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	588	Shared Neighborhood Hits	60
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TROAP_HUMAN
NC score	0.048151 (rank : 46)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

HRX_HUMAN
NC score	0.047287 (rank : 47)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	825	Shared Neighborhood Hits	59
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SYNJ1_MOUSE
NC score	0.045899 (rank : 48)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	516	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZIMP7_MOUSE
NC score	0.045736 (rank : 49)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	566	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

WIRE_HUMAN
NC score	0.043302 (rank : 50)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

HEAT1_HUMAN
NC score	0.043197 (rank : 51)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

3BP1_HUMAN
NC score	0.042789 (rank : 52)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	376	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MUC1_HUMAN
NC score	0.042131 (rank : 53)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	975	Shared Neighborhood Hits	78
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PCLO_MOUSE
NC score	0.041256 (rank : 54)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	2275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SON_HUMAN
NC score	0.040556 (rank : 55)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	1568	Shared Neighborhood Hits	107
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BLNK_MOUSE
NC score	0.039891 (rank : 56)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	296	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

ITSN1_MOUSE
NC score	0.039623 (rank : 57)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	1669	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

JHD2B_HUMAN
NC score	0.038959 (rank : 58)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

SPT5H_MOUSE
NC score	0.038438 (rank : 59)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	437	Shared Neighborhood Hits	49
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

WIRE_MOUSE
NC score	0.038411 (rank : 60)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SPT5H_HUMAN
NC score	0.037967 (rank : 61)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	436	Shared Neighborhood Hits	47
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

ITSN1_HUMAN
NC score	0.037960 (rank : 62)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	1757	Shared Neighborhood Hits	79
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

3BP1_MOUSE
NC score	0.037939 (rank : 63)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	238	Shared Neighborhood Hits	30
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MLL2_HUMAN
NC score	0.037932 (rank : 64)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	1788	Shared Neighborhood Hits	92
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ARI5B_MOUSE
NC score	0.037911 (rank : 65)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	158	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

CJ012_HUMAN
NC score	0.037385 (rank : 66)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

TARA_HUMAN
NC score	0.037122 (rank : 67)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GRIN1_HUMAN
NC score	0.037109 (rank : 68)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	681	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NFH_MOUSE
NC score	0.037098 (rank : 69)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	2247	Shared Neighborhood Hits	109
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GRAP_HUMAN
NC score	0.037000 (rank : 70)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	307	Shared Neighborhood Hits	31
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

LRP10_MOUSE
NC score	0.036683 (rank : 71)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

GRAP_MOUSE
NC score	0.036641 (rank : 72)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	309	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

CIC_HUMAN
NC score	0.035863 (rank : 73)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	992	Shared Neighborhood Hits	76
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

OGFR_HUMAN
NC score	0.035737 (rank : 74)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	1582	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LRP10_HUMAN
NC score	0.035324 (rank : 75)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CNOT4_MOUSE
NC score	0.034666 (rank : 76)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	277	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

MISS_MOUSE
NC score	0.034618 (rank : 77)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	444	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

CIC_MOUSE
NC score	0.034231 (rank : 78)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	742	Shared Neighborhood Hits	67
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ZN292_HUMAN
NC score	0.034086 (rank : 79)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	918	Shared Neighborhood Hits	22
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

MINT_MOUSE
NC score	0.033934 (rank : 80)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	1514	Shared Neighborhood Hits	89
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SYNJ1_HUMAN
NC score	0.033618 (rank : 81)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	498	Shared Neighborhood Hits	60
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

K1802_HUMAN
NC score	0.033280 (rank : 82)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	1378	Shared Neighborhood Hits	79
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ST5_MOUSE
NC score	0.032615 (rank : 83)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

ERRFI_HUMAN
NC score	0.032497 (rank : 84)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

TM108_HUMAN
NC score	0.032354 (rank : 85)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	166	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

RFIP1_HUMAN
NC score	0.032298 (rank : 86)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SPN90_MOUSE
NC score	0.031845 (rank : 87)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

DIDO1_HUMAN
NC score	0.031797 (rank : 88)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	960	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

RD23A_HUMAN
NC score	0.031551 (rank : 89)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	P54725	Gene names	RAD23A
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (hHR23A).

CABYR_MOUSE
NC score	0.031073 (rank : 90)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CK024_MOUSE
NC score	0.030377 (rank : 91)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

RD23A_MOUSE
NC score	0.030075 (rank : 92)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

MINT_HUMAN
NC score	0.029703 (rank : 93)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	1291	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CIZ1_HUMAN
NC score	0.029587 (rank : 94)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	359	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

RTN4_MOUSE
NC score	0.029242 (rank : 95)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	341	Shared Neighborhood Hits	36
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

ARI1B_HUMAN
NC score	0.029183 (rank : 96)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	567	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CNOT4_HUMAN
NC score	0.028922 (rank : 97)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

PTN23_HUMAN
NC score	0.028877 (rank : 98)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	646	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

TENS1_HUMAN
NC score	0.028738 (rank : 99)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	400	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

SI1L1_MOUSE
NC score	0.028670 (rank : 100)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	189	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

MBD5_HUMAN
NC score	0.028193 (rank : 101)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

AFF3_HUMAN
NC score	0.028117 (rank : 102)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	190	Shared Neighborhood Hits	27
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

AMOT_HUMAN
NC score	0.028046 (rank : 103)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	712	Shared Neighborhood Hits	41
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

RUSC2_MOUSE
NC score	0.027194 (rank : 104)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

AB1IP_HUMAN
NC score	0.027007 (rank : 105)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	213	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

JHD2B_MOUSE
NC score	0.026919 (rank : 106)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

RIMS1_HUMAN
NC score	0.026493 (rank : 107)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	437	Shared Neighborhood Hits	28
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

ZC3H3_MOUSE
NC score	0.026275 (rank : 108)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

PO2F2_HUMAN
NC score	0.026170 (rank : 109)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	379	Shared Neighborhood Hits	16
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

ZIMP7_HUMAN
NC score	0.025737 (rank : 110)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	290	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

GON4L_MOUSE
NC score	0.025645 (rank : 111)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	455	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IRS2_MOUSE
NC score	0.025475 (rank : 112)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

NEBU_HUMAN
NC score	0.025241 (rank : 113)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	420	Shared Neighborhood Hits	27
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NCOR2_MOUSE
NC score	0.024772 (rank : 114)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	790	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NRG2_HUMAN
NC score	0.024310 (rank : 115)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

DIAP1_HUMAN
NC score	0.023889 (rank : 116)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	784	Shared Neighborhood Hits	39
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

B4GN4_HUMAN
NC score	0.023617 (rank : 117)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

SYTL2_HUMAN
NC score	0.023586 (rank : 118)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

NGEF_MOUSE
NC score	0.023452 (rank : 119)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARI4A_HUMAN
NC score	0.023312 (rank : 120)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	434	Shared Neighborhood Hits	16
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

K0423_HUMAN
NC score	0.022754 (rank : 121)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

CSKI2_HUMAN
NC score	0.022663 (rank : 122)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	747	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PTN23_MOUSE
NC score	0.022395 (rank : 123)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	726	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SI1L3_HUMAN
NC score	0.022191 (rank : 124)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	41
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

GP158_HUMAN
NC score	0.021729 (rank : 125)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

TULP1_HUMAN
NC score	0.021392 (rank : 126)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

HCN4_MOUSE
NC score	0.020904 (rank : 127)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	284	Shared Neighborhood Hits	32
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

ZMYM3_HUMAN
NC score	0.020039 (rank : 128)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

FXL19_MOUSE
NC score	0.019819 (rank : 129)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

MYT1L_MOUSE
NC score	0.019573 (rank : 130)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	461	Shared Neighborhood Hits	13
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

ZMYM3_MOUSE
NC score	0.019488 (rank : 131)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

CSKI1_HUMAN
NC score	0.019475 (rank : 132)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	997	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FOXR1_HUMAN
NC score	0.019417 (rank : 133)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PIV2, Q86UT9, Q8IXX2	Gene names	FOXR1, DLNB13, FOXN5
Domain Architecture	No domain graphic available
Description	Forkhead box protein R1 (Forkhead box protein N5).

SI1L1_HUMAN
NC score	0.018770 (rank : 134)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

TDRD4_HUMAN
NC score	0.018391 (rank : 135)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

USH1C_MOUSE
NC score	0.018076 (rank : 136)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	557	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

NFM_HUMAN
NC score	0.017842 (rank : 137)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	1328	Shared Neighborhood Hits	61
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TBCD3_HUMAN
NC score	0.017474 (rank : 138)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

COFA1_MOUSE
NC score	0.017179 (rank : 139)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

MILK2_HUMAN
NC score	0.017127 (rank : 140)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

HPS4_MOUSE
NC score	0.016520 (rank : 141)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

SYEP_HUMAN
NC score	0.016289 (rank : 142)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

LPP_HUMAN
NC score	0.016163 (rank : 143)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	775	Shared Neighborhood Hits	65
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

RIF1_HUMAN
NC score	0.015942 (rank : 144)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	320	Shared Neighborhood Hits	13
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

CCD45_MOUSE
NC score	0.015657 (rank : 145)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	663	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CN037_MOUSE
NC score	0.015557 (rank : 146)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

FREA_MOUSE
NC score	0.015476 (rank : 147)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

IL6RA_HUMAN
NC score	0.014967 (rank : 148)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

CAF1A_HUMAN
NC score	0.014929 (rank : 149)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	750	Shared Neighborhood Hits	27
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

PO2F2_MOUSE
NC score	0.014844 (rank : 150)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

TTP_HUMAN
NC score	0.014563 (rank : 151)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

NPAS1_MOUSE
NC score	0.014538 (rank : 152)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

M3K9_HUMAN
NC score	0.014490 (rank : 153)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	1123	Shared Neighborhood Hits	47
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NCA11_MOUSE
NC score	0.014418 (rank : 154)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	661	Shared Neighborhood Hits	41
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PTPRN_HUMAN
NC score	0.013917 (rank : 155)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

ANM8_HUMAN
NC score	0.013388 (rank : 156)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR22, Q8TBJ8	Gene names	PRMT8, HRMT1L3, HRMT1L4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

CAF1B_MOUSE
NC score	0.013352 (rank : 157)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	385	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

IC1_MOUSE
NC score	0.013252 (rank : 158)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

DC1L2_MOUSE
NC score	0.013107 (rank : 159)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

BUB1_HUMAN
NC score	0.013020 (rank : 160)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

IF4G3_HUMAN
NC score	0.012469 (rank : 161)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	247	Shared Neighborhood Hits	21
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MAMC2_HUMAN
NC score	0.012382 (rank : 162)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NAF1_MOUSE
NC score	0.012287 (rank : 163)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	852	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

GP1BA_HUMAN
NC score	0.012067 (rank : 164)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	407	Shared Neighborhood Hits	29
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

NU153_HUMAN
NC score	0.011543 (rank : 165)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

LYN_MOUSE
NC score	0.011491 (rank : 166)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	1023	Shared Neighborhood Hits	33
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CO8A_MOUSE
NC score	0.011316 (rank : 167)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

NOLA1_MOUSE
NC score	0.010848 (rank : 168)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CY66, Q80X93, Q8C6C5, Q8VDH0	Gene names	Nola1, Gar1
Domain Architecture	No domain graphic available
Description	H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1).

LYN_HUMAN
NC score	0.010648 (rank : 169)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	1022	Shared Neighborhood Hits	32
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CAC1D_HUMAN
NC score	0.010487 (rank : 170)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

LR37B_HUMAN
NC score	0.010194 (rank : 171)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	392	Shared Neighborhood Hits	26
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

DC1L2_HUMAN
NC score	0.010090 (rank : 172)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	O43237, Q8TAT3	Gene names	DYNC1LI2, DNCLI2, LIC2
Domain Architecture
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC53/55) (LIC-2).

MYO15_HUMAN
NC score	0.009839 (rank : 173)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	671	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CAC1H_HUMAN
NC score	0.009707 (rank : 174)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	307	Shared Neighborhood Hits	25
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

ANM8_MOUSE
NC score	0.009660 (rank : 175)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PAK3, Q7M6Z2	Gene names	Prmt8, Hrmt1l4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

SMP1L_HUMAN
NC score	0.009646 (rank : 176)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

BPA1_MOUSE
NC score	0.009631 (rank : 177)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	1477	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

UN13B_HUMAN
NC score	0.009346 (rank : 178)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PLCB1_HUMAN
NC score	0.009016 (rank : 179)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	614	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

M3K10_HUMAN
NC score	0.008637 (rank : 180)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	1071	Shared Neighborhood Hits	35
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

LPHN1_HUMAN
NC score	0.008629 (rank : 181)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	155	Shared Neighborhood Hits	7
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

PLCB1_MOUSE
NC score	0.008543 (rank : 182)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	531	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

TMCC1_HUMAN
NC score	0.008221 (rank : 183)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	8
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TSH2_MOUSE
NC score	0.007956 (rank : 184)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

WDHD1_HUMAN
NC score	0.007927 (rank : 185)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CUL4B_HUMAN
NC score	0.007655 (rank : 186)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

NFAC1_MOUSE
NC score	0.007639 (rank : 187)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

EPAS1_HUMAN
NC score	0.007238 (rank : 188)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

SN1L1_HUMAN
NC score	0.007187 (rank : 189)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	911	Shared Neighborhood Hits	22
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

CAC1E_MOUSE
NC score	0.007154 (rank : 190)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

ZBTB4_HUMAN
NC score	0.007135 (rank : 191)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	926	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

ATP7B_MOUSE
NC score	0.006854 (rank : 192)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q64446	Gene names	Atp7b, Wnd
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein homolog).

PLXB3_HUMAN
NC score	0.006374 (rank : 193)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

CRBB3_MOUSE
NC score	0.005962 (rank : 194)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJU9	Gene names	Crybb3
Domain Architecture
Description	Beta crystallin B3 (Beta-B3-crystallin).

ZN516_MOUSE
NC score	0.005887 (rank : 195)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	1197	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

GOGA4_HUMAN
NC score	0.005487 (rank : 196)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	2034	Shared Neighborhood Hits	46
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HXA3_MOUSE
NC score	0.005460 (rank : 197)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	558	Shared Neighborhood Hits	40
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

OBSCN_HUMAN
NC score	0.005431 (rank : 198)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	1931	Shared Neighborhood Hits	80
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

KCNC3_HUMAN
NC score	0.005152 (rank : 199)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	256	Shared Neighborhood Hits	26
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

NMDE3_HUMAN
NC score	0.004630 (rank : 200)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

KIRR2_MOUSE
NC score	0.004481 (rank : 201)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	326	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

ABL1_MOUSE
NC score	0.004140 (rank : 202)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	1178	Shared Neighborhood Hits	48
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SMRCD_HUMAN
NC score	0.003852 (rank : 203)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

LYAM2_MOUSE
NC score	0.003735 (rank : 204)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CDON_MOUSE
NC score	0.003443 (rank : 205)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	410	Shared Neighborhood Hits	8
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

WNK3_HUMAN
NC score	0.003102 (rank : 206)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	948	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

JAG2_MOUSE
NC score	0.002187 (rank : 207)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	504	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LATS1_HUMAN
NC score	0.002148 (rank : 208)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	1057	Shared Neighborhood Hits	36
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

M4K4_HUMAN
NC score	0.001717 (rank : 209)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	1589	Shared Neighborhood Hits	35
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NOTC3_MOUSE
NC score	0.001317 (rank : 210)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].