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Network neighborhood for query Sequence : CAC1E_MOUSE

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CAC1E_MOUSE
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1A_HUMAN
θ value	0 (rank : 1)	NC score	0.968489 (rank : 6)
Query Neighborhood Hits	167	Target Neighborhood Hits	387	Shared Neighborhood Hits	73
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0 (rank : 2)	NC score	0.977841 (rank : 3)
Query Neighborhood Hits	167	Target Neighborhood Hits	267	Shared Neighborhood Hits	74
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	0 (rank : 3)	NC score	0.976469 (rank : 4)
Query Neighborhood Hits	167	Target Neighborhood Hits	257	Shared Neighborhood Hits	68
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0 (rank : 4)	NC score	0.973342 (rank : 5)
Query Neighborhood Hits	167	Target Neighborhood Hits	351	Shared Neighborhood Hits	74
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_HUMAN
θ value	0 (rank : 5)	NC score	0.956957 (rank : 13)
Query Neighborhood Hits	167	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	0 (rank : 6)	NC score	0.958504 (rank : 12)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	0 (rank : 7)	NC score	0.959422 (rank : 11)
Query Neighborhood Hits	167	Target Neighborhood Hits	118	Shared Neighborhood Hits	58
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	0 (rank : 8)	NC score	0.997796 (rank : 2)
Query Neighborhood Hits	167	Target Neighborhood Hits	148	Shared Neighborhood Hits	113
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0 (rank : 9)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	167	Target Neighborhood Hits	167	Shared Neighborhood Hits	167
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	0 (rank : 10)	NC score	0.960243 (rank : 10)
Query Neighborhood Hits	167	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0 (rank : 11)	NC score	0.960455 (rank : 9)
Query Neighborhood Hits	167	Target Neighborhood Hits	142	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	0 (rank : 12)	NC score	0.961648 (rank : 8)
Query Neighborhood Hits	167	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	0 (rank : 13)	NC score	0.962186 (rank : 7)
Query Neighborhood Hits	167	Target Neighborhood Hits	98	Shared Neighborhood Hits	57
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN2A_HUMAN
θ value	4.83544e-70 (rank : 14)	NC score	0.856358 (rank : 25)
Query Neighborhood Hits	167	Target Neighborhood Hits	157	Shared Neighborhood Hits	62
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
θ value	4.83544e-70 (rank : 15)	NC score	0.856030 (rank : 27)
Query Neighborhood Hits	167	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN4A_HUMAN
θ value	6.31527e-70 (rank : 16)	NC score	0.865661 (rank : 20)
Query Neighborhood Hits	167	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN1A_HUMAN
θ value	4.09345e-69 (rank : 17)	NC score	0.855745 (rank : 28)
Query Neighborhood Hits	167	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1G_HUMAN
θ value	9.11921e-69 (rank : 18)	NC score	0.863495 (rank : 21)
Query Neighborhood Hits	167	Target Neighborhood Hits	587	Shared Neighborhood Hits	68
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC11A_HUMAN
θ value	9.11921e-69 (rank : 19)	NC score	0.870185 (rank : 18)
Query Neighborhood Hits	167	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN3A_HUMAN
θ value	1.5555e-68 (rank : 20)	NC score	0.858264 (rank : 23)
Query Neighborhood Hits	167	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_MOUSE
θ value	2.03155e-68 (rank : 21)	NC score	0.857750 (rank : 24)
Query Neighborhood Hits	167	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN8A_HUMAN
θ value	2.03155e-68 (rank : 22)	NC score	0.856352 (rank : 26)
Query Neighborhood Hits	167	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	2.03155e-68 (rank : 23)	NC score	0.854025 (rank : 29)
Query Neighborhood Hits	167	Target Neighborhood Hits	136	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1H_MOUSE
θ value	2.65329e-68 (rank : 24)	NC score	0.881842 (rank : 15)
Query Neighborhood Hits	167	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	2.65329e-68 (rank : 25)	NC score	0.904291 (rank : 14)
Query Neighborhood Hits	167	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_HUMAN
θ value	5.91091e-68 (rank : 26)	NC score	0.877552 (rank : 16)
Query Neighborhood Hits	167	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
θ value	9.43692e-66 (rank : 27)	NC score	0.871853 (rank : 17)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN5A_HUMAN
θ value	1.2325e-65 (rank : 28)	NC score	0.867231 (rank : 19)
Query Neighborhood Hits	167	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SC10A_HUMAN
θ value	3.58603e-65 (rank : 29)	NC score	0.853254 (rank : 30)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN7A_HUMAN
θ value	8.55514e-59 (rank : 30)	NC score	0.862984 (rank : 22)
Query Neighborhood Hits	167	Target Neighborhood Hits	135	Shared Neighborhood Hits	50
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

PKD2_MOUSE
θ value	3.08544e-08 (rank : 31)	NC score	0.347024 (rank : 34)
Query Neighborhood Hits	167	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L2_HUMAN
θ value	2.21117e-06 (rank : 32)	NC score	0.382014 (rank : 31)
Query Neighborhood Hits	167	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	4.92598e-06 (rank : 33)	NC score	0.349167 (rank : 33)
Query Neighborhood Hits	167	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
θ value	1.87187e-05 (rank : 34)	NC score	0.355071 (rank : 32)
Query Neighborhood Hits	167	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PKD2_HUMAN
θ value	1.87187e-05 (rank : 35)	NC score	0.332170 (rank : 35)
Query Neighborhood Hits	167	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCND2_HUMAN
θ value	3.19293e-05 (rank : 36)	NC score	0.183720 (rank : 46)
Query Neighborhood Hits	167	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	3.19293e-05 (rank : 37)	NC score	0.183898 (rank : 45)
Query Neighborhood Hits	167	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
θ value	3.19293e-05 (rank : 38)	NC score	0.189952 (rank : 42)
Query Neighborhood Hits	167	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	3.19293e-05 (rank : 39)	NC score	0.190019 (rank : 41)
Query Neighborhood Hits	167	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNV2_HUMAN
θ value	0.000602161 (rank : 40)	NC score	0.226747 (rank : 37)
Query Neighborhood Hits	167	Target Neighborhood Hits	137	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNF1_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.236226 (rank : 36)
Query Neighborhood Hits	167	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCND1_MOUSE
θ value	0.00134147 (rank : 42)	NC score	0.171625 (rank : 47)
Query Neighborhood Hits	167	Target Neighborhood Hits	165	Shared Neighborhood Hits	51
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
θ value	0.00175202 (rank : 43)	NC score	0.167737 (rank : 48)
Query Neighborhood Hits	167	Target Neighborhood Hits	160	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS2_MOUSE
θ value	0.00390308 (rank : 44)	NC score	0.201963 (rank : 39)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	53
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	0.00869519 (rank : 45)	NC score	0.197505 (rank : 40)
Query Neighborhood Hits	167	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

MCPH1_MOUSE
θ value	0.00869519 (rank : 46)	NC score	0.043712 (rank : 92)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MCLN2_MOUSE
θ value	0.0193708 (rank : 47)	NC score	0.083221 (rank : 65)
Query Neighborhood Hits	167	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

RBBP6_MOUSE
θ value	0.0193708 (rank : 48)	NC score	0.039503 (rank : 96)
Query Neighborhood Hits	167	Target Neighborhood Hits	1014	Shared Neighborhood Hits	36
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ANK2_HUMAN
θ value	0.0736092 (rank : 49)	NC score	0.009221 (rank : 127)
Query Neighborhood Hits	167	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

KCNB2_HUMAN
θ value	0.0736092 (rank : 50)	NC score	0.203732 (rank : 38)
Query Neighborhood Hits	167	Target Neighborhood Hits	212	Shared Neighborhood Hits	56
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

TRPM8_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.061021 (rank : 80)
Query Neighborhood Hits	167	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

NIPBL_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.045257 (rank : 91)
Query Neighborhood Hits	167	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

GPR63_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.007406 (rank : 134)
Query Neighborhood Hits	167	Target Neighborhood Hits	774	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQQ3	Gene names	Gpr63
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

TGON2_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.029388 (rank : 100)
Query Neighborhood Hits	167	Target Neighborhood Hits	1037	Shared Neighborhood Hits	39
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TPTE2_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.143630 (rank : 50)
Query Neighborhood Hits	167	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

DMN_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.009032 (rank : 128)
Query Neighborhood Hits	167	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

KCNC4_MOUSE
θ value	0.21417 (rank : 57)	NC score	0.121559 (rank : 56)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG3_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.108753 (rank : 59)
Query Neighborhood Hits	167	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

TCF20_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.027208 (rank : 101)
Query Neighborhood Hits	167	Target Neighborhood Hits	396	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TCP10_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.041315 (rank : 95)
Query Neighborhood Hits	167	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

TRPM8_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.055364 (rank : 86)
Query Neighborhood Hits	167	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

PO6F2_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.016331 (rank : 105)
Query Neighborhood Hits	167	Target Neighborhood Hits	618	Shared Neighborhood Hits	17
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

ULK2_MOUSE
θ value	0.279714 (rank : 63)	NC score	-0.001333 (rank : 186)
Query Neighborhood Hits	167	Target Neighborhood Hits	943	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

KCNB1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.189109 (rank : 44)
Query Neighborhood Hits	167	Target Neighborhood Hits	169	Shared Neighborhood Hits	53
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.189142 (rank : 43)
Query Neighborhood Hits	167	Target Neighborhood Hits	154	Shared Neighborhood Hits	53
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

RBBP6_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.033870 (rank : 97)
Query Neighborhood Hits	167	Target Neighborhood Hits	1135	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CENPC_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.031534 (rank : 98)
Query Neighborhood Hits	167	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

FAT2_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.005149 (rank : 159)
Query Neighborhood Hits	167	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

KCNC4_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.128732 (rank : 54)
Query Neighborhood Hits	167	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC1_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.135337 (rank : 52)
Query Neighborhood Hits	167	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

MY18A_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.003219 (rank : 170)
Query Neighborhood Hits	167	Target Neighborhood Hits	1929	Shared Neighborhood Hits	46
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GPR63_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.004972 (rank : 160)
Query Neighborhood Hits	167	Target Neighborhood Hits	776	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZJ6, Q9UJH3	Gene names	GPR63, PSP24B
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

KCNC1_MOUSE
θ value	0.813845 (rank : 73)	NC score	0.133354 (rank : 53)
Query Neighborhood Hits	167	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNG3_MOUSE
θ value	0.813845 (rank : 74)	NC score	0.105473 (rank : 61)
Query Neighborhood Hits	167	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

SN1L2_HUMAN
θ value	1.06291 (rank : 75)	NC score	-0.002226 (rank : 191)
Query Neighborhood Hits	167	Target Neighborhood Hits	964	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

SPT5H_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.015381 (rank : 107)
Query Neighborhood Hits	167	Target Neighborhood Hits	437	Shared Neighborhood Hits	20
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

FA47A_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.015352 (rank : 108)
Query Neighborhood Hits	167	Target Neighborhood Hits	451	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

NPBL_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.051499 (rank : 87)
Query Neighborhood Hits	167	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SN1L2_MOUSE
θ value	1.38821 (rank : 79)	NC score	-0.002522 (rank : 192)
Query Neighborhood Hits	167	Target Neighborhood Hits	944	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

ARID2_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.012199 (rank : 118)
Query Neighborhood Hits	167	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

DIDO1_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.027105 (rank : 102)
Query Neighborhood Hits	167	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MYST3_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.008056 (rank : 131)
Query Neighborhood Hits	167	Target Neighborhood Hits	772	Shared Neighborhood Hits	34
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

OVGP1_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.006824 (rank : 139)
Query Neighborhood Hits	167	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q62010	Gene names	Ovgp1, Chit5, Ogp
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein).

PRDM2_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.001178 (rank : 176)
Query Neighborhood Hits	167	Target Neighborhood Hits	1135	Shared Neighborhood Hits	22
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SRTD2_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.013568 (rank : 112)
Query Neighborhood Hits	167	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

TPTE_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.100221 (rank : 62)
Query Neighborhood Hits	167	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TRPC4_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.041416 (rank : 94)
Query Neighborhood Hits	167	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

ZN318_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.020670 (rank : 104)
Query Neighborhood Hits	167	Target Neighborhood Hits	642	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

INVO_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.010953 (rank : 120)
Query Neighborhood Hits	167	Target Neighborhood Hits	474	Shared Neighborhood Hits	22
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

PKDRE_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.083806 (rank : 64)
Query Neighborhood Hits	167	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

SORC3_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.005602 (rank : 154)
Query Neighborhood Hits	167	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

TRPC4_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.042916 (rank : 93)
Query Neighborhood Hits	167	Target Neighborhood Hits	140	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TTC16_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.026460 (rank : 103)
Query Neighborhood Hits	167	Target Neighborhood Hits	417	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

BOREA_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.012567 (rank : 114)
Query Neighborhood Hits	167	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q53HL2, Q53HN1, Q96AM3, Q9NVW5	Gene names	CDCA8, PESCRG3
Domain Architecture	No domain graphic available
Description	Borealin (Dasra-B) (hDasra-B) (Cell division cycle-associated protein 8) (Pluripotent embryonic stem cell-related gene 3 protein).

DCJ14_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.007772 (rank : 132)
Query Neighborhood Hits	167	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Y2X3, Q66K17, Q96N59, Q96T63	Gene names	DNAJC14, DRIP78
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14 (Dopamine receptor-interacting protein of 78 kDa) (DRiP78).

JIP2_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.014705 (rank : 109)
Query Neighborhood Hits	167	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TRI55_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.005420 (rank : 155)
Query Neighborhood Hits	167	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

CD2_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.013864 (rank : 110)
Query Neighborhood Hits	167	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CHFR_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.006220 (rank : 144)
Query Neighborhood Hits	167	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CT174_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.013735 (rank : 111)
Query Neighborhood Hits	167	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DHX36_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.006410 (rank : 142)
Query Neighborhood Hits	167	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

IKKE_MOUSE
θ value	4.03905 (rank : 102)	NC score	-0.001790 (rank : 189)
Query Neighborhood Hits	167	Target Neighborhood Hits	848	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

KCNS3_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.167314 (rank : 49)
Query Neighborhood Hits	167	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

MBN3_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.010133 (rank : 123)
Query Neighborhood Hits	167	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

MYST4_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.007112 (rank : 136)
Query Neighborhood Hits	167	Target Neighborhood Hits	671	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

RB15B_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.015865 (rank : 106)
Query Neighborhood Hits	167	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SON_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.012564 (rank : 115)
Query Neighborhood Hits	167	Target Neighborhood Hits	957	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TBC10_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.006987 (rank : 138)
Query Neighborhood Hits	167	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

VN1B8_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.005348 (rank : 157)
Query Neighborhood Hits	167	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQ45	Gene names	V1rb8, V1ra13
Domain Architecture	No domain graphic available
Description	Vomeronasal type-1 receptor B8 (Vomeronasal type-1 receptor A13).

AK1A1_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.006540 (rank : 140)
Query Neighborhood Hits	167	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P14550	Gene names	AKR1A1, ALDR1, ALR
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

CDKL5_HUMAN
θ value	5.27518 (rank : 111)	NC score	-0.001855 (rank : 190)
Query Neighborhood Hits	167	Target Neighborhood Hits	967	Shared Neighborhood Hits	17
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

GLU2B_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.012228 (rank : 117)
Query Neighborhood Hits	167	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

NCOR2_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.007549 (rank : 133)
Query Neighborhood Hits	167	Target Neighborhood Hits	790	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

OSBL5_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.003795 (rank : 166)
Query Neighborhood Hits	167	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

RB15B_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.009431 (rank : 125)
Query Neighborhood Hits	167	Target Neighborhood Hits	251	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SEM6D_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.001111 (rank : 177)
Query Neighborhood Hits	167	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SIAL_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.010222 (rank : 122)
Query Neighborhood Hits	167	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q61711, Q61363	Gene names	Ibsp
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

SPTB2_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.005738 (rank : 152)
Query Neighborhood Hits	167	Target Neighborhood Hits	748	Shared Neighborhood Hits	24
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.005641 (rank : 153)
Query Neighborhood Hits	167	Target Neighborhood Hits	770	Shared Neighborhood Hits	24
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN2_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.005988 (rank : 146)
Query Neighborhood Hits	167	Target Neighborhood Hits	535	Shared Neighborhood Hits	20
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SYTL2_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.004392 (rank : 165)
Query Neighborhood Hits	167	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TSN17_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.006269 (rank : 143)
Query Neighborhood Hits	167	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FV3, Q96S98, Q9UKB9	Gene names	TSPAN17, FBXO23, TM4SF17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

TSN17_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.006459 (rank : 141)
Query Neighborhood Hits	167	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7W4, Q91VI6	Gene names	Tspan17, Fbxo23, Tm4sf17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

TUFT1_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.003208 (rank : 171)
Query Neighborhood Hits	167	Target Neighborhood Hits	732	Shared Neighborhood Hits	20
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TXLNB_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.003730 (rank : 167)
Query Neighborhood Hits	167	Target Neighborhood Hits	912	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

UTX_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.005150 (rank : 158)
Query Neighborhood Hits	167	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

WNK1_HUMAN
θ value	5.27518 (rank : 127)	NC score	-0.001153 (rank : 185)
Query Neighborhood Hits	167	Target Neighborhood Hits	1158	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZCH11_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.006215 (rank : 145)
Query Neighborhood Hits	167	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

CMGA_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.009532 (rank : 124)
Query Neighborhood Hits	167	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

DHX36_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.005854 (rank : 147)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

EVPL_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.001055 (rank : 178)
Query Neighborhood Hits	167	Target Neighborhood Hits	895	Shared Neighborhood Hits	22
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

GP73_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.005753 (rank : 151)
Query Neighborhood Hits	167	Target Neighborhood Hits	309	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

KCNQ5_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.059409 (rank : 81)
Query Neighborhood Hits	167	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

MMRN2_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.004600 (rank : 164)
Query Neighborhood Hits	167	Target Neighborhood Hits	400	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

PKDRE_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.107262 (rank : 60)
Query Neighborhood Hits	167	Target Neighborhood Hits	64	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

SNPC4_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.011439 (rank : 119)
Query Neighborhood Hits	167	Target Neighborhood Hits	589	Shared Neighborhood Hits	20
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SRRM2_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.029800 (rank : 99)
Query Neighborhood Hits	167	Target Neighborhood Hits	1296	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TLR8_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.000475 (rank : 179)
Query Neighborhood Hits	167	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

TTF2_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.005833 (rank : 149)
Query Neighborhood Hits	167	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TTLL4_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.003695 (rank : 168)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

TXND2_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.012792 (rank : 113)
Query Neighborhood Hits	167	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UN45A_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.004707 (rank : 162)
Query Neighborhood Hits	167	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

AK1A1_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.004927 (rank : 161)
Query Neighborhood Hits	167	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3	Gene names	Akr1a1, Akr1a4
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

CI078_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.009242 (rank : 126)
Query Neighborhood Hits	167	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ63, Q8WVU6, Q9NT39	Gene names	C9orf78
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59).

CI078_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.008349 (rank : 130)
Query Neighborhood Hits	167	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TQI7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 homolog.

CP250_HUMAN
θ value	8.99809 (rank : 146)	NC score	-0.001345 (rank : 187)
Query Neighborhood Hits	167	Target Neighborhood Hits	1805	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DOCK4_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.005808 (rank : 150)
Query Neighborhood Hits	167	Target Neighborhood Hits	237	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.007154 (rank : 135)
Query Neighborhood Hits	167	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

ELF1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.001506 (rank : 175)
Query Neighborhood Hits	167	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

F120C_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.005836 (rank : 148)
Query Neighborhood Hits	167	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

FYCO1_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.000240 (rank : 180)
Query Neighborhood Hits	167	Target Neighborhood Hits	1059	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

ITSN1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.000073 (rank : 182)
Query Neighborhood Hits	167	Target Neighborhood Hits	1669	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

JARD2_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.008976 (rank : 129)
Query Neighborhood Hits	167	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JIP2_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.012407 (rank : 116)
Query Neighborhood Hits	167	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JPH2_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.010659 (rank : 121)
Query Neighborhood Hits	167	Target Neighborhood Hits	639	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KCNS1_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.141710 (rank : 51)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

LAP2_HUMAN
θ value	8.99809 (rank : 157)	NC score	-0.001449 (rank : 188)
Query Neighborhood Hits	167	Target Neighborhood Hits	499	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MACF1_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.002204 (rank : 174)
Query Neighborhood Hits	167	Target Neighborhood Hits	1341	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.002687 (rank : 173)
Query Neighborhood Hits	167	Target Neighborhood Hits	1321	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

NTBP1_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.003221 (rank : 169)
Query Neighborhood Hits	167	Target Neighborhood Hits	528	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

PELP1_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.004627 (rank : 163)
Query Neighborhood Hits	167	Target Neighborhood Hits	596	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RABE1_HUMAN
θ value	8.99809 (rank : 162)	NC score	-0.000103 (rank : 183)
Query Neighborhood Hits	167	Target Neighborhood Hits	1104	Shared Neighborhood Hits	27
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	8.99809 (rank : 163)	NC score	-0.000315 (rank : 184)
Query Neighborhood Hits	167	Target Neighborhood Hits	1105	Shared Neighborhood Hits	26
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RIMS1_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.003195 (rank : 172)
Query Neighborhood Hits	167	Target Neighborhood Hits	437	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SDCG8_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.000116 (rank : 181)
Query Neighborhood Hits	167	Target Neighborhood Hits	886	Shared Neighborhood Hits	23
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TTC28_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.007042 (rank : 137)
Query Neighborhood Hits	167	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

UBP28_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.005405 (rank : 156)
Query Neighborhood Hits	167	Target Neighborhood Hits	178	Shared Neighborhood Hits	9
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

KCNA1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.082074 (rank : 66)
Query Neighborhood Hits	167	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.083932 (rank : 63)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.075585 (rank : 70)
Query Neighborhood Hits	167	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.076465 (rank : 68)
Query Neighborhood Hits	167	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.067380 (rank : 76)
Query Neighborhood Hits	167	Target Neighborhood Hits	101	Shared Neighborhood Hits	31
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.066411 (rank : 77)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.056464 (rank : 84)
Query Neighborhood Hits	167	Target Neighborhood Hits	108	Shared Neighborhood Hits	24
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.056821 (rank : 83)
Query Neighborhood Hits	167	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.064407 (rank : 78)
Query Neighborhood Hits	167	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.069995 (rank : 73)
Query Neighborhood Hits	167	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.072862 (rank : 71)
Query Neighborhood Hits	167	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.078381 (rank : 67)
Query Neighborhood Hits	167	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC3_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.110952 (rank : 57)
Query Neighborhood Hits	167	Target Neighborhood Hits	256	Shared Neighborhood Hits	57
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.109356 (rank : 58)
Query Neighborhood Hits	167	Target Neighborhood Hits	173	Shared Neighborhood Hits	50
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.070689 (rank : 72)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.068113 (rank : 75)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.063421 (rank : 79)
Query Neighborhood Hits	167	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.057649 (rank : 82)
Query Neighborhood Hits	167	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.069448 (rank : 74)
Query Neighborhood Hits	167	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.050074 (rank : 90)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	27
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.051159 (rank : 89)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.076409 (rank : 69)
Query Neighborhood Hits	167	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNS1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.125857 (rank : 55)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MCLN2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.051489 (rank : 88)
Query Neighborhood Hits	167	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

TRPV3_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.055774 (rank : 85)
Query Neighborhood Hits	167	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1E_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 9)
Query Neighborhood Hits	167	Target Neighborhood Hits	167	Shared Neighborhood Hits	167
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.997796 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	167	Target Neighborhood Hits	148	Shared Neighborhood Hits	113
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.977841 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	167	Target Neighborhood Hits	267	Shared Neighborhood Hits	74
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
NC score	0.976469 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	167	Target Neighborhood Hits	257	Shared Neighborhood Hits	68
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
NC score	0.973342 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	167	Target Neighborhood Hits	351	Shared Neighborhood Hits	74
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
NC score	0.968489 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	167	Target Neighborhood Hits	387	Shared Neighborhood Hits	73
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1S_MOUSE
NC score	0.962186 (rank : 7)	θ value	0 (rank : 13)
Query Neighborhood Hits	167	Target Neighborhood Hits	98	Shared Neighborhood Hits	57
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_HUMAN
NC score	0.961648 (rank : 8)	θ value	0 (rank : 12)
Query Neighborhood Hits	167	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_MOUSE
NC score	0.960455 (rank : 9)	θ value	0 (rank : 11)
Query Neighborhood Hits	167	Target Neighborhood Hits	142	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.960243 (rank : 10)	θ value	0 (rank : 10)
Query Neighborhood Hits	167	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1D_HUMAN
NC score	0.959422 (rank : 11)	θ value	0 (rank : 7)
Query Neighborhood Hits	167	Target Neighborhood Hits	118	Shared Neighborhood Hits	58
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1C_MOUSE
NC score	0.958504 (rank : 12)	θ value	0 (rank : 6)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.956957 (rank : 13)	θ value	0 (rank : 5)
Query Neighborhood Hits	167	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1I_HUMAN
NC score	0.904291 (rank : 14)	θ value	2.65329e-68 (rank : 25)
Query Neighborhood Hits	167	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.881842 (rank : 15)	θ value	2.65329e-68 (rank : 24)
Query Neighborhood Hits	167	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.877552 (rank : 16)	θ value	5.91091e-68 (rank : 26)
Query Neighborhood Hits	167	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
NC score	0.871853 (rank : 17)	θ value	9.43692e-66 (rank : 27)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.870185 (rank : 18)	θ value	9.11921e-69 (rank : 19)
Query Neighborhood Hits	167	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN5A_HUMAN
NC score	0.867231 (rank : 19)	θ value	1.2325e-65 (rank : 28)
Query Neighborhood Hits	167	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN4A_HUMAN
NC score	0.865661 (rank : 20)	θ value	6.31527e-70 (rank : 16)
Query Neighborhood Hits	167	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

CAC1G_HUMAN
NC score	0.863495 (rank : 21)	θ value	9.11921e-69 (rank : 18)
Query Neighborhood Hits	167	Target Neighborhood Hits	587	Shared Neighborhood Hits	68
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN7A_HUMAN
NC score	0.862984 (rank : 22)	θ value	8.55514e-59 (rank : 30)
Query Neighborhood Hits	167	Target Neighborhood Hits	135	Shared Neighborhood Hits	50
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN3A_HUMAN
NC score	0.858264 (rank : 23)	θ value	1.5555e-68 (rank : 20)
Query Neighborhood Hits	167	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_MOUSE
NC score	0.857750 (rank : 24)	θ value	2.03155e-68 (rank : 21)
Query Neighborhood Hits	167	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN2A_HUMAN
NC score	0.856358 (rank : 25)	θ value	4.83544e-70 (rank : 14)
Query Neighborhood Hits	167	Target Neighborhood Hits	157	Shared Neighborhood Hits	62
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN8A_HUMAN
NC score	0.856352 (rank : 26)	θ value	2.03155e-68 (rank : 22)
Query Neighborhood Hits	167	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
NC score	0.856030 (rank : 27)	θ value	4.83544e-70 (rank : 15)
Query Neighborhood Hits	167	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN1A_HUMAN
NC score	0.855745 (rank : 28)	θ value	4.09345e-69 (rank : 17)
Query Neighborhood Hits	167	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN8A_MOUSE
NC score	0.854025 (rank : 29)	θ value	2.03155e-68 (rank : 23)
Query Neighborhood Hits	167	Target Neighborhood Hits	136	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
NC score	0.853254 (rank : 30)	θ value	3.58603e-65 (rank : 29)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

PK2L2_HUMAN
NC score	0.382014 (rank : 31)	θ value	2.21117e-06 (rank : 32)
Query Neighborhood Hits	167	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.355071 (rank : 32)	θ value	1.87187e-05 (rank : 34)
Query Neighborhood Hits	167	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.349167 (rank : 33)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	167	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.347024 (rank : 34)	θ value	3.08544e-08 (rank : 31)
Query Neighborhood Hits	167	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.332170 (rank : 35)	θ value	1.87187e-05 (rank : 35)
Query Neighborhood Hits	167	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.236226 (rank : 36)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	167	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.226747 (rank : 37)	θ value	0.000602161 (rank : 40)
Query Neighborhood Hits	167	Target Neighborhood Hits	137	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.203732 (rank : 38)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	167	Target Neighborhood Hits	212	Shared Neighborhood Hits	56
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.201963 (rank : 39)	θ value	0.00390308 (rank : 44)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	53
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.197505 (rank : 40)	θ value	0.00869519 (rank : 45)
Query Neighborhood Hits	167	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCND3_MOUSE
NC score	0.190019 (rank : 41)	θ value	3.19293e-05 (rank : 39)
Query Neighborhood Hits	167	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.189952 (rank : 42)	θ value	3.19293e-05 (rank : 38)
Query Neighborhood Hits	167	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNB1_MOUSE
NC score	0.189142 (rank : 43)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	167	Target Neighborhood Hits	154	Shared Neighborhood Hits	53
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.189109 (rank : 44)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	167	Target Neighborhood Hits	169	Shared Neighborhood Hits	53
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND2_MOUSE
NC score	0.183898 (rank : 45)	θ value	3.19293e-05 (rank : 37)
Query Neighborhood Hits	167	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.183720 (rank : 46)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	167	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.171625 (rank : 47)	θ value	0.00134147 (rank : 42)
Query Neighborhood Hits	167	Target Neighborhood Hits	165	Shared Neighborhood Hits	51
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.167737 (rank : 48)	θ value	0.00175202 (rank : 43)
Query Neighborhood Hits	167	Target Neighborhood Hits	160	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS3_HUMAN
NC score	0.167314 (rank : 49)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	167	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

TPTE2_HUMAN
NC score	0.143630 (rank : 50)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	167	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_HUMAN
NC score	0.141710 (rank : 51)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.135337 (rank : 52)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	167	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.133354 (rank : 53)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	167	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.128732 (rank : 54)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	167	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS1_MOUSE
NC score	0.125857 (rank : 55)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_MOUSE
NC score	0.121559 (rank : 56)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	167	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.110952 (rank : 57)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	167	Target Neighborhood Hits	256	Shared Neighborhood Hits	57
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.109356 (rank : 58)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	167	Target Neighborhood Hits	173	Shared Neighborhood Hits	50
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG3_HUMAN
NC score	0.108753 (rank : 59)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	167	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PKDRE_HUMAN
NC score	0.107262 (rank : 60)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	167	Target Neighborhood Hits	64	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG3_MOUSE
NC score	0.105473 (rank : 61)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	167	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

TPTE_HUMAN
NC score	0.100221 (rank : 62)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	167	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNA1_MOUSE
NC score	0.083932 (rank : 63)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

PKDRE_MOUSE
NC score	0.083806 (rank : 64)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	167	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

MCLN2_MOUSE
NC score	0.083221 (rank : 65)	θ value	0.0193708 (rank : 47)
Query Neighborhood Hits	167	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNA1_HUMAN
NC score	0.082074 (rank : 66)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	167	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA6_MOUSE
NC score	0.078381 (rank : 67)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	167	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA2_MOUSE
NC score	0.076465 (rank : 68)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	167	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNQ4_HUMAN
NC score	0.076409 (rank : 69)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	167	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNA2_HUMAN
NC score	0.075585 (rank : 70)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	167	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_HUMAN
NC score	0.072862 (rank : 71)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	167	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNG1_HUMAN
NC score	0.070689 (rank : 72)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA5_MOUSE
NC score	0.069995 (rank : 73)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	167	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNQ1_MOUSE
NC score	0.069448 (rank : 74)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	167	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNG2_HUMAN
NC score	0.068113 (rank : 75)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	167	Target Neighborhood Hits	83	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA3_HUMAN
NC score	0.067380 (rank : 76)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	167	Target Neighborhood Hits	101	Shared Neighborhood Hits	31
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
NC score	0.066411 (rank : 77)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.064407 (rank : 78)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	167	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNG4_HUMAN
NC score	0.063421 (rank : 79)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	167	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

TRPM8_MOUSE
NC score	0.061021 (rank : 80)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	167	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

KCNQ5_HUMAN
NC score	0.059409 (rank : 81)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	167	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ1_HUMAN
NC score	0.057649 (rank : 82)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	167	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA4_MOUSE
NC score	0.056821 (rank : 83)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	167	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.056464 (rank : 84)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	167	Target Neighborhood Hits	108	Shared Neighborhood Hits	24
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

TRPV3_HUMAN
NC score	0.055774 (rank : 85)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	167	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPM8_HUMAN
NC score	0.055364 (rank : 86)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	167	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

NPBL_MOUSE
NC score	0.051499 (rank : 87)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	167	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MCLN2_HUMAN
NC score	0.051489 (rank : 88)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	167	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNQ3_HUMAN
NC score	0.051159 (rank : 89)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_HUMAN
NC score	0.050074 (rank : 90)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	27
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

NIPBL_HUMAN
NC score	0.045257 (rank : 91)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	167	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MCPH1_MOUSE
NC score	0.043712 (rank : 92)	θ value	0.00869519 (rank : 46)
Query Neighborhood Hits	167	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

TRPC4_HUMAN
NC score	0.042916 (rank : 93)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	167	Target Neighborhood Hits	140	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.041416 (rank : 94)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	167	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TCP10_HUMAN
NC score	0.041315 (rank : 95)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	167	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

RBBP6_MOUSE
NC score	0.039503 (rank : 96)	θ value	0.0193708 (rank : 48)
Query Neighborhood Hits	167	Target Neighborhood Hits	1014	Shared Neighborhood Hits	36
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBBP6_HUMAN
NC score	0.033870 (rank : 97)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	167	Target Neighborhood Hits	1135	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CENPC_MOUSE
NC score	0.031534 (rank : 98)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	167	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

SRRM2_HUMAN
NC score	0.029800 (rank : 99)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	167	Target Neighborhood Hits	1296	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TGON2_HUMAN
NC score	0.029388 (rank : 100)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	167	Target Neighborhood Hits	1037	Shared Neighborhood Hits	39
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TCF20_MOUSE
NC score	0.027208 (rank : 101)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	167	Target Neighborhood Hits	396	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

DIDO1_HUMAN
NC score	0.027105 (rank : 102)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	167	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TTC16_HUMAN
NC score	0.026460 (rank : 103)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	167	Target Neighborhood Hits	417	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ZN318_MOUSE
NC score	0.020670 (rank : 104)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	167	Target Neighborhood Hits	642	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

PO6F2_HUMAN
NC score	0.016331 (rank : 105)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	167	Target Neighborhood Hits	618	Shared Neighborhood Hits	17
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

RB15B_MOUSE
NC score	0.015865 (rank : 106)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	167	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SPT5H_MOUSE
NC score	0.015381 (rank : 107)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	167	Target Neighborhood Hits	437	Shared Neighborhood Hits	20
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

FA47A_HUMAN
NC score	0.015352 (rank : 108)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	167	Target Neighborhood Hits	451	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

JIP2_MOUSE
NC score	0.014705 (rank : 109)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	167	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

CD2_HUMAN
NC score	0.013864 (rank : 110)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	167	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CT174_HUMAN
NC score	0.013735 (rank : 111)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	167	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

SRTD2_HUMAN
NC score	0.013568 (rank : 112)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	167	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

TXND2_MOUSE
NC score	0.012792 (rank : 113)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	167	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BOREA_HUMAN
NC score	0.012567 (rank : 114)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	167	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q53HL2, Q53HN1, Q96AM3, Q9NVW5	Gene names	CDCA8, PESCRG3
Domain Architecture	No domain graphic available
Description	Borealin (Dasra-B) (hDasra-B) (Cell division cycle-associated protein 8) (Pluripotent embryonic stem cell-related gene 3 protein).

SON_MOUSE
NC score	0.012564 (rank : 115)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	167	Target Neighborhood Hits	957	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

JIP2_HUMAN
NC score	0.012407 (rank : 116)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	167	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

GLU2B_MOUSE
NC score	0.012228 (rank : 117)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	167	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ARID2_HUMAN
NC score	0.012199 (rank : 118)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	167	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

SNPC4_HUMAN
NC score	0.011439 (rank : 119)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	167	Target Neighborhood Hits	589	Shared Neighborhood Hits	20
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

INVO_MOUSE
NC score	0.010953 (rank : 120)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	167	Target Neighborhood Hits	474	Shared Neighborhood Hits	22
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

JPH2_HUMAN
NC score	0.010659 (rank : 121)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	167	Target Neighborhood Hits	639	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SIAL_MOUSE
NC score	0.010222 (rank : 122)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	167	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q61711, Q61363	Gene names	Ibsp
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

MBN3_MOUSE
NC score	0.010133 (rank : 123)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	167	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

CMGA_MOUSE
NC score	0.009532 (rank : 124)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	167	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

RB15B_HUMAN
NC score	0.009431 (rank : 125)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	167	Target Neighborhood Hits	251	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

CI078_HUMAN
NC score	0.009242 (rank : 126)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	167	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ63, Q8WVU6, Q9NT39	Gene names	C9orf78
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59).

ANK2_HUMAN
NC score	0.009221 (rank : 127)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	167	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

DMN_HUMAN
NC score	0.009032 (rank : 128)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	167	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

JARD2_MOUSE
NC score	0.008976 (rank : 129)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	167	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

CI078_MOUSE
NC score	0.008349 (rank : 130)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	167	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TQI7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 homolog.

MYST3_HUMAN
NC score	0.008056 (rank : 131)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	167	Target Neighborhood Hits	772	Shared Neighborhood Hits	34
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

DCJ14_HUMAN
NC score	0.007772 (rank : 132)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	167	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Y2X3, Q66K17, Q96N59, Q96T63	Gene names	DNAJC14, DRIP78
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14 (Dopamine receptor-interacting protein of 78 kDa) (DRiP78).

NCOR2_MOUSE
NC score	0.007549 (rank : 133)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	167	Target Neighborhood Hits	790	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

GPR63_MOUSE
NC score	0.007406 (rank : 134)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	167	Target Neighborhood Hits	774	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQQ3	Gene names	Gpr63
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

DOCK4_MOUSE
NC score	0.007154 (rank : 135)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	167	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MYST4_HUMAN
NC score	0.007112 (rank : 136)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	167	Target Neighborhood Hits	671	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TTC28_HUMAN
NC score	0.007042 (rank : 137)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	167	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TBC10_MOUSE
NC score	0.006987 (rank : 138)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	167	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

OVGP1_MOUSE
NC score	0.006824 (rank : 139)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	167	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q62010	Gene names	Ovgp1, Chit5, Ogp
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein).

AK1A1_HUMAN
NC score	0.006540 (rank : 140)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	167	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P14550	Gene names	AKR1A1, ALDR1, ALR
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

TSN17_MOUSE
NC score	0.006459 (rank : 141)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	167	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7W4, Q91VI6	Gene names	Tspan17, Fbxo23, Tm4sf17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

DHX36_HUMAN
NC score	0.006410 (rank : 142)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	167	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

TSN17_HUMAN
NC score	0.006269 (rank : 143)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	167	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FV3, Q96S98, Q9UKB9	Gene names	TSPAN17, FBXO23, TM4SF17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

CHFR_HUMAN
NC score	0.006220 (rank : 144)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	167	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

ZCH11_HUMAN
NC score	0.006215 (rank : 145)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	167	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

SPTN2_HUMAN
NC score	0.005988 (rank : 146)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	167	Target Neighborhood Hits	535	Shared Neighborhood Hits	20
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

DHX36_MOUSE
NC score	0.005854 (rank : 147)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	167	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

F120C_MOUSE
NC score	0.005836 (rank : 148)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	167	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

TTF2_MOUSE
NC score	0.005833 (rank : 149)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	167	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

DOCK4_HUMAN
NC score	0.005808 (rank : 150)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	167	Target Neighborhood Hits	237	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

GP73_HUMAN
NC score	0.005753 (rank : 151)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	167	Target Neighborhood Hits	309	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

SPTB2_HUMAN
NC score	0.005738 (rank : 152)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	167	Target Neighborhood Hits	748	Shared Neighborhood Hits	24
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.005641 (rank : 153)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	167	Target Neighborhood Hits	770	Shared Neighborhood Hits	24
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SORC3_HUMAN
NC score	0.005602 (rank : 154)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	167	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

TRI55_HUMAN
NC score	0.005420 (rank : 155)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	167	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

UBP28_MOUSE
NC score	0.005405 (rank : 156)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	167	Target Neighborhood Hits	178	Shared Neighborhood Hits	9
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

VN1B8_MOUSE
NC score	0.005348 (rank : 157)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	167	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQ45	Gene names	V1rb8, V1ra13
Domain Architecture	No domain graphic available
Description	Vomeronasal type-1 receptor B8 (Vomeronasal type-1 receptor A13).

UTX_HUMAN
NC score	0.005150 (rank : 158)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	167	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

FAT2_HUMAN
NC score	0.005149 (rank : 159)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	167	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

GPR63_HUMAN
NC score	0.004972 (rank : 160)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	167	Target Neighborhood Hits	776	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZJ6, Q9UJH3	Gene names	GPR63, PSP24B
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

AK1A1_MOUSE
NC score	0.004927 (rank : 161)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	167	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3	Gene names	Akr1a1, Akr1a4
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

UN45A_MOUSE
NC score	0.004707 (rank : 162)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	167	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

PELP1_HUMAN
NC score	0.004627 (rank : 163)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	167	Target Neighborhood Hits	596	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

MMRN2_HUMAN
NC score	0.004600 (rank : 164)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	167	Target Neighborhood Hits	400	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

SYTL2_HUMAN
NC score	0.004392 (rank : 165)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	167	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

OSBL5_HUMAN
NC score	0.003795 (rank : 166)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	167	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

TXLNB_HUMAN
NC score	0.003730 (rank : 167)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	167	Target Neighborhood Hits	912	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TTLL4_MOUSE
NC score	0.003695 (rank : 168)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	167	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

NTBP1_MOUSE
NC score	0.003221 (rank : 169)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	167	Target Neighborhood Hits	528	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

MY18A_HUMAN
NC score	0.003219 (rank : 170)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	167	Target Neighborhood Hits	1929	Shared Neighborhood Hits	46
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TUFT1_MOUSE
NC score	0.003208 (rank : 171)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	167	Target Neighborhood Hits	732	Shared Neighborhood Hits	20
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

RIMS1_HUMAN
NC score	0.003195 (rank : 172)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	167	Target Neighborhood Hits	437	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

MACF4_HUMAN
NC score	0.002687 (rank : 173)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	167	Target Neighborhood Hits	1321	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.002204 (rank : 174)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	167	Target Neighborhood Hits	1341	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

ELF1_HUMAN
NC score	0.001506 (rank : 175)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	167	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

PRDM2_HUMAN
NC score	0.001178 (rank : 176)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	167	Target Neighborhood Hits	1135	Shared Neighborhood Hits	22
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SEM6D_HUMAN
NC score	0.001111 (rank : 177)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	167	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

EVPL_HUMAN
NC score	0.001055 (rank : 178)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	167	Target Neighborhood Hits	895	Shared Neighborhood Hits	22
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

TLR8_MOUSE
NC score	0.000475 (rank : 179)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	167	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

FYCO1_MOUSE
NC score	0.000240 (rank : 180)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	167	Target Neighborhood Hits	1059	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

SDCG8_MOUSE
NC score	0.000116 (rank : 181)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	167	Target Neighborhood Hits	886	Shared Neighborhood Hits	23
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

ITSN1_MOUSE
NC score	0.000073 (rank : 182)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	167	Target Neighborhood Hits	1669	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

RABE1_HUMAN
NC score	-0.000103 (rank : 183)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	167	Target Neighborhood Hits	1104	Shared Neighborhood Hits	27
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
NC score	-0.000315 (rank : 184)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	167	Target Neighborhood Hits	1105	Shared Neighborhood Hits	26
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

WNK1_HUMAN
NC score	-0.001153 (rank : 185)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	167	Target Neighborhood Hits	1158	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ULK2_MOUSE
NC score	-0.001333 (rank : 186)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	167	Target Neighborhood Hits	943	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

CP250_HUMAN
NC score	-0.001345 (rank : 187)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	167	Target Neighborhood Hits	1805	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

LAP2_HUMAN
NC score	-0.001449 (rank : 188)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	167	Target Neighborhood Hits	499	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

IKKE_MOUSE
NC score	-0.001790 (rank : 189)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	167	Target Neighborhood Hits	848	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

CDKL5_HUMAN
NC score	-0.001855 (rank : 190)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	167	Target Neighborhood Hits	967	Shared Neighborhood Hits	17
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

SN1L2_HUMAN
NC score	-0.002226 (rank : 191)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	167	Target Neighborhood Hits	964	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

SN1L2_MOUSE
NC score	-0.002522 (rank : 192)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	167	Target Neighborhood Hits	944	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).