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Network neighborhood for query Sequence : SCN8A_HUMAN

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SCN8A_HUMAN
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SC10A_HUMAN
θ value	0 (rank : 1)	NC score	0.992552 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC10A_MOUSE
θ value	0 (rank : 2)	NC score	0.992864 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC11A_HUMAN
θ value	0 (rank : 3)	NC score	0.982358 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	111	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	0 (rank : 4)	NC score	0.983310 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN1A_HUMAN
θ value	0 (rank : 5)	NC score	0.994527 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN2A_HUMAN
θ value	0 (rank : 6)	NC score	0.994530 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	80
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	0 (rank : 7)	NC score	0.994894 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN4A_HUMAN
θ value	0 (rank : 8)	NC score	0.991349 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
θ value	0 (rank : 9)	NC score	0.986249 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	145	Shared Neighborhood Hits	71
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN7A_HUMAN
θ value	0 (rank : 10)	NC score	0.985606 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN8A_HUMAN
θ value	0 (rank : 11)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	0 (rank : 12)	NC score	0.999273 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
θ value	0 (rank : 13)	NC score	0.993884 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1D_HUMAN
θ value	1.96316e-71 (rank : 14)	NC score	0.845320 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	59
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1A_MOUSE
θ value	4.37348e-71 (rank : 15)	NC score	0.851964 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	267	Shared Neighborhood Hits	60
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1I_HUMAN
θ value	9.74306e-71 (rank : 16)	NC score	0.891536 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	138	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1S_MOUSE
θ value	2.83479e-70 (rank : 17)	NC score	0.847105 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1A_HUMAN
θ value	4.83544e-70 (rank : 18)	NC score	0.844449 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	387	Shared Neighborhood Hits	61
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1E_MOUSE
θ value	2.03155e-68 (rank : 19)	NC score	0.856352 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
θ value	5.91091e-68 (rank : 20)	NC score	0.855689 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1B_MOUSE
θ value	7.71989e-68 (rank : 21)	NC score	0.843001 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	351	Shared Neighborhood Hits	64
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_MOUSE
θ value	1.71981e-67 (rank : 22)	NC score	0.840606 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
θ value	6.53529e-67 (rank : 23)	NC score	0.839791 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	8.53533e-67 (rank : 24)	NC score	0.845260 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	92	Shared Neighborhood Hits	54
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1H_MOUSE
θ value	7.98882e-65 (rank : 25)	NC score	0.871373 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
θ value	6.76295e-64 (rank : 26)	NC score	0.864236 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1B_HUMAN
θ value	8.83269e-64 (rank : 27)	NC score	0.845797 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	257	Shared Neighborhood Hits	63
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_MOUSE
θ value	8.26713e-62 (rank : 28)	NC score	0.837505 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	55
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1G_HUMAN
θ value	5.92465e-60 (rank : 29)	NC score	0.847406 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	587	Shared Neighborhood Hits	63
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1C_HUMAN
θ value	6.55044e-59 (rank : 30)	NC score	0.832798 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

KCNF1_HUMAN
θ value	0.00020696 (rank : 31)	NC score	0.230632 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNB2_HUMAN
θ value	0.000270298 (rank : 32)	NC score	0.213500 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	212	Shared Neighborhood Hits	56
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
θ value	0.00035302 (rank : 33)	NC score	0.205886 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	0.000602161 (rank : 34)	NC score	0.200630 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_HUMAN
θ value	0.00228821 (rank : 35)	NC score	0.193642 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	169	Shared Neighborhood Hits	57
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.00228821 (rank : 36)	NC score	0.193685 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNV2_HUMAN
θ value	0.00390308 (rank : 37)	NC score	0.213732 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCND2_HUMAN
θ value	0.00665767 (rank : 38)	NC score	0.169457 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.00665767 (rank : 39)	NC score	0.169629 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
θ value	0.00665767 (rank : 40)	NC score	0.176692 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.00665767 (rank : 41)	NC score	0.176808 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNQ1_MOUSE
θ value	0.00869519 (rank : 42)	NC score	0.082316 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	175	Shared Neighborhood Hits	38
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.073582 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PKD2_MOUSE
θ value	0.0563607 (rank : 44)	NC score	0.257510 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	47
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L1_HUMAN
θ value	0.0736092 (rank : 45)	NC score	0.273156 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.295015 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

SP17_HUMAN
θ value	0.0961366 (rank : 47)	NC score	0.062499 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q15506, Q9BXF7	Gene names	SPA17, SP17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17) (Sperm protein 17) (Sp17-1).

MY18A_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.006430 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	1929	Shared Neighborhood Hits	36
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRPV3_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.097519 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNC1_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.142949 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCND1_MOUSE
θ value	0.163984 (rank : 51)	NC score	0.150530 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

SYNE2_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.008135 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	1323	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

KCNC1_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.140636 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

TRPV3_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.069909 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

KCNS3_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.173467 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND1_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.148601 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

TRPV1_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.045395 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	184	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

CABP5_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.056728 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

KCNC3_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.117630 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PKD2_HUMAN
θ value	0.47712 (rank : 60)	NC score	0.252575 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

BRDT_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.012755 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

KCNC3_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.115535 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TCF17_MOUSE
θ value	0.62314 (rank : 63)	NC score	-0.003708 (rank : 154)
Query Neighborhood Hits	135	Target Neighborhood Hits	786	Shared Neighborhood Hits	6
SwissProt Accessions	Q61751	Gene names	Znf354a, Kid1, Tcf17, Zfp354a
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Renal transcription factor Kid-1) (Kidney, ischemia, and developmentally- regulated protein 1).

KCNC4_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.124623 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.118017 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

SP17_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.060062 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q62252	Gene names	Spa17, Sp17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17).

STK10_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.000845 (rank : 147)
Query Neighborhood Hits	135	Target Neighborhood Hits	1921	Shared Neighborhood Hits	29
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK39_HUMAN
θ value	0.813845 (rank : 68)	NC score	-0.000968 (rank : 149)
Query Neighborhood Hits	135	Target Neighborhood Hits	882	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

TRPC1_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.069094 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.069190 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPV4_HUMAN
θ value	0.813845 (rank : 71)	NC score	0.064767 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	150	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	0.813845 (rank : 72)	NC score	0.066301 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CK5P2_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.010705 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	1433	Shared Neighborhood Hits	29
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

PK2L2_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.258838 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPC4_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.041213 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

JHD3C_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.008263 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

K0423_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.014333 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

PKDRE_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.111722 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	64	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TRPC4_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.041901 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	140	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

UBP8_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.004006 (rank : 138)
Query Neighborhood Hits	135	Target Neighborhood Hits	751	Shared Neighborhood Hits	21
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

A16L1_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.010745 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	776	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

AKAP6_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.018116 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CABP5_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.040825 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

DDX49_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.010862 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

GOGA4_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.005141 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	2034	Shared Neighborhood Hits	35
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

PKDRE_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.087104 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

RUSC2_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.018521 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	305	Shared Neighborhood Hits	8
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CXA12_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.003811 (rank : 139)
Query Neighborhood Hits	135	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T442, O43440, Q7Z7J2, Q8IWJ9	Gene names	GJA12
Domain Architecture	No domain graphic available
Description	Gap junction alpha-12 protein (Connexin-47) (Cx47) (Connexin-46.6) (Cx46.6).

DIDO1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.016827 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	960	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

HIP1R_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.007305 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

NCOA7_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.015955 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

STK10_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.000626 (rank : 148)
Query Neighborhood Hits	135	Target Neighborhood Hits	2132	Shared Neighborhood Hits	34
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CING_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.001761 (rank : 145)
Query Neighborhood Hits	135	Target Neighborhood Hits	1432	Shared Neighborhood Hits	27
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

DYSF_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.007133 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

HMMR_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.004692 (rank : 136)
Query Neighborhood Hits	135	Target Neighborhood Hits	1082	Shared Neighborhood Hits	22
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

KCNS1_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.137242 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MINT_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.009592 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	1514	Shared Neighborhood Hits	19
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OLF9_MOUSE
θ value	3.0926 (rank : 98)	NC score	-0.001379 (rank : 151)
Query Neighborhood Hits	135	Target Neighborhood Hits	700	Shared Neighborhood Hits	9
SwissProt Accessions	Q60885, Q8VGC0	Gene names	Olfr9, Mor269-3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 9 (Olfactory receptor 269-3) (Odorant receptor M25).

ZBT16_HUMAN
θ value	3.0926 (rank : 99)	NC score	-0.004328 (rank : 156)
Query Neighborhood Hits	135	Target Neighborhood Hits	1010	Shared Neighborhood Hits	5
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

LAMC1_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.001076 (rank : 146)
Query Neighborhood Hits	135	Target Neighborhood Hits	856	Shared Neighborhood Hits	15
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NOP14_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.012999 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	324	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

ZN318_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.016148 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	497	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

CCD47_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.012108 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	7
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

GNRP_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.005038 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

KCNQ3_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.054975 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	34
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.054374 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MERL_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.002528 (rank : 143)
Query Neighborhood Hits	135	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PSMD2_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.010338 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

PSN2_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.032172 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q61144, O54977, P97934, P97935, Q91VS3, Q9D616	Gene names	Psen2, Ad4h, Alg3, Ps-2, Psnl2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

UBP1_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.004359 (rank : 137)
Query Neighborhood Hits	135	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

ZNF34_HUMAN
θ value	5.27518 (rank : 111)	NC score	-0.004364 (rank : 157)
Query Neighborhood Hits	135	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZ26	Gene names	ZNF34, KOX32
Domain Architecture	No domain graphic available
Description	Zinc finger protein 34 (Zinc finger protein KOX32).

A16L1_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.006019 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	664	Shared Neighborhood Hits	17
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

AFAD_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.006402 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	689	Shared Neighborhood Hits	23
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CKLF4_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.011013 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CJ61, Q8K143	Gene names	Cmtm4, Cklfsf4
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4).

DIAP2_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.010694 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

FA86A_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.011396 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G04, Q96S85	Gene names	FAM86A
Domain Architecture	No domain graphic available
Description	Protein FAM86A.

GNRP_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.003094 (rank : 140)
Query Neighborhood Hits	135	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GPR32_HUMAN
θ value	6.88961 (rank : 118)	NC score	-0.001601 (rank : 152)
Query Neighborhood Hits	135	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	O75388, Q6NWS5	Gene names	GPR32
Domain Architecture
Description	Probable G-protein coupled receptor 32.

KCNS1_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.119335 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	49
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MYO3B_HUMAN
θ value	6.88961 (rank : 120)	NC score	-0.002508 (rank : 153)
Query Neighborhood Hits	135	Target Neighborhood Hits	923	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

TP53B_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.017796 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	644	Shared Neighborhood Hits	11
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UBN1_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.011019 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

ANR26_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.002792 (rank : 141)
Query Neighborhood Hits	135	Target Neighborhood Hits	1614	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CALB2_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.018757 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	149	Shared Neighborhood Hits	14
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.019113 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CHL1_MOUSE
θ value	8.99809 (rank : 126)	NC score	-0.001032 (rank : 150)
Query Neighborhood Hits	135	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CKLF4_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.009455 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZR5, Q8IZR4, Q8IZV1	Gene names	CMTM4, CKLFSF4
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4).

CTRO_MOUSE
θ value	8.99809 (rank : 128)	NC score	-0.003963 (rank : 155)
Query Neighborhood Hits	135	Target Neighborhood Hits	2344	Shared Neighborhood Hits	30
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DNJC8_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.006688 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	380	Shared Neighborhood Hits	14
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.006832 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

GOGA2_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.009495 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	944	Shared Neighborhood Hits	22
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

RRBP1_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.002501 (rank : 144)
Query Neighborhood Hits	135	Target Neighborhood Hits	1650	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SSX3_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.002534 (rank : 142)
Query Neighborhood Hits	135	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q99909, O60223, Q5JQZ3	Gene names	SSX3
Domain Architecture
Description	Protein SSX3.

TM131_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.013520 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

VIGLN_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.008787 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

KCNA1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.078790 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.080142 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.076775 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.077591 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.069943 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.069096 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.056613 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.057099 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.066005 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	124	Shared Neighborhood Hits	32
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.071231 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	36
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.072129 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.074984 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.069985 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.063266 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.089752 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.090138 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG4_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.062157 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.052318 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.084258 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	38
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.062667 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TPTE2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.127691 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

TPTE_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.084536 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

Hits sorted by NC score

SCN8A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.999273 (rank : 2)	θ value	0 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN3A_HUMAN
NC score	0.994894 (rank : 3)	θ value	0 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN2A_HUMAN
NC score	0.994530 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	80
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN1A_HUMAN
NC score	0.994527 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN9A_HUMAN
NC score	0.993884 (rank : 6)	θ value	0 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SC10A_MOUSE
NC score	0.992864 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC10A_HUMAN
NC score	0.992552 (rank : 8)	θ value	0 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN4A_HUMAN
NC score	0.991349 (rank : 9)	θ value	0 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
NC score	0.986249 (rank : 10)	θ value	0 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	145	Shared Neighborhood Hits	71
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN7A_HUMAN
NC score	0.985606 (rank : 11)	θ value	0 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SC11A_MOUSE
NC score	0.983310 (rank : 12)	θ value	0 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.982358 (rank : 13)	θ value	0 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	111	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CAC1I_HUMAN
NC score	0.891536 (rank : 14)	θ value	9.74306e-71 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	138	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.871373 (rank : 15)	θ value	7.98882e-65 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.864236 (rank : 16)	θ value	6.76295e-64 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1E_MOUSE
NC score	0.856352 (rank : 17)	θ value	2.03155e-68 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.855689 (rank : 18)	θ value	5.91091e-68 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.851964 (rank : 19)	θ value	4.37348e-71 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	267	Shared Neighborhood Hits	60
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1G_HUMAN
NC score	0.847406 (rank : 20)	θ value	5.92465e-60 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	587	Shared Neighborhood Hits	63
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1S_MOUSE
NC score	0.847105 (rank : 21)	θ value	2.83479e-70 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_HUMAN
NC score	0.845797 (rank : 22)	θ value	8.83269e-64 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	257	Shared Neighborhood Hits	63
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1D_HUMAN
NC score	0.845320 (rank : 23)	θ value	1.96316e-71 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	59
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_HUMAN
NC score	0.845260 (rank : 24)	θ value	8.53533e-67 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	92	Shared Neighborhood Hits	54
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1A_HUMAN
NC score	0.844449 (rank : 25)	θ value	4.83544e-70 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	387	Shared Neighborhood Hits	61
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_MOUSE
NC score	0.843001 (rank : 26)	θ value	7.71989e-68 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	351	Shared Neighborhood Hits	64
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_MOUSE
NC score	0.840606 (rank : 27)	θ value	1.71981e-67 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.839791 (rank : 28)	θ value	6.53529e-67 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1C_MOUSE
NC score	0.837505 (rank : 29)	θ value	8.26713e-62 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	55
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.832798 (rank : 30)	θ value	6.55044e-59 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.295015 (rank : 31)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.273156 (rank : 32)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.258838 (rank : 33)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.257510 (rank : 34)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	47
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.252575 (rank : 35)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.230632 (rank : 36)	θ value	0.00020696 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.213732 (rank : 37)	θ value	0.00390308 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.213500 (rank : 38)	θ value	0.000270298 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	212	Shared Neighborhood Hits	56
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.205886 (rank : 39)	θ value	0.00035302 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.200630 (rank : 40)	θ value	0.000602161 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.193685 (rank : 41)	θ value	0.00228821 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.193642 (rank : 42)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	169	Shared Neighborhood Hits	57
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND3_MOUSE
NC score	0.176808 (rank : 43)	θ value	0.00665767 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.176692 (rank : 44)	θ value	0.00665767 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS3_HUMAN
NC score	0.173467 (rank : 45)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND2_MOUSE
NC score	0.169629 (rank : 46)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.169457 (rank : 47)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.150530 (rank : 48)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.148601 (rank : 49)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNC1_HUMAN
NC score	0.142949 (rank : 50)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.140636 (rank : 51)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNS1_HUMAN
NC score	0.137242 (rank : 52)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
NC score	0.127691 (rank : 53)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	135	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNC4_HUMAN
NC score	0.124623 (rank : 54)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS1_MOUSE
NC score	0.119335 (rank : 55)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	49
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_MOUSE
NC score	0.118017 (rank : 56)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.117630 (rank : 57)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.115535 (rank : 58)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PKDRE_HUMAN
NC score	0.111722 (rank : 59)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	64	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TRPV3_HUMAN
NC score	0.097519 (rank : 60)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNG3_MOUSE
NC score	0.090138 (rank : 61)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
NC score	0.089752 (rank : 62)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PKDRE_MOUSE
NC score	0.087104 (rank : 63)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TPTE_HUMAN
NC score	0.084536 (rank : 64)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNQ4_HUMAN
NC score	0.084258 (rank : 65)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	38
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ1_MOUSE
NC score	0.082316 (rank : 66)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	175	Shared Neighborhood Hits	38
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA1_MOUSE
NC score	0.080142 (rank : 67)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.078790 (rank : 68)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_MOUSE
NC score	0.077591 (rank : 69)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.076775 (rank : 70)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_MOUSE
NC score	0.074984 (rank : 71)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNQ1_HUMAN
NC score	0.073582 (rank : 72)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA6_HUMAN
NC score	0.072129 (rank : 73)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_MOUSE
NC score	0.071231 (rank : 74)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	36
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNG1_HUMAN
NC score	0.069985 (rank : 75)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA3_HUMAN
NC score	0.069943 (rank : 76)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

TRPV3_MOUSE
NC score	0.069909 (rank : 77)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPC1_MOUSE
NC score	0.069190 (rank : 78)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

KCNA3_MOUSE
NC score	0.069096 (rank : 79)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

TRPC1_HUMAN
NC score	0.069094 (rank : 80)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPV4_MOUSE
NC score	0.066301 (rank : 81)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

KCNA5_HUMAN
NC score	0.066005 (rank : 82)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	135	Target Neighborhood Hits	124	Shared Neighborhood Hits	32
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

TRPV4_HUMAN
NC score	0.064767 (rank : 83)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	150	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

KCNG2_HUMAN
NC score	0.063266 (rank : 84)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	135	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNQ5_HUMAN
NC score	0.062667 (rank : 85)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

SP17_HUMAN
NC score	0.062499 (rank : 86)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q15506, Q9BXF7	Gene names	SPA17, SP17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17) (Sperm protein 17) (Sp17-1).

KCNG4_HUMAN
NC score	0.062157 (rank : 87)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

SP17_MOUSE
NC score	0.060062 (rank : 88)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q62252	Gene names	Spa17, Sp17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17).

KCNA4_MOUSE
NC score	0.057099 (rank : 89)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

CABP5_MOUSE
NC score	0.056728 (rank : 90)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

KCNA4_HUMAN
NC score	0.056613 (rank : 91)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ3_HUMAN
NC score	0.054975 (rank : 92)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	34
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.054374 (rank : 93)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_HUMAN
NC score	0.052318 (rank : 94)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

TRPV1_HUMAN
NC score	0.045395 (rank : 95)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	184	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPC4_HUMAN
NC score	0.041901 (rank : 96)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	140	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.041213 (rank : 97)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

CABP5_HUMAN
NC score	0.040825 (rank : 98)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

PSN2_MOUSE
NC score	0.032172 (rank : 99)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q61144, O54977, P97934, P97935, Q91VS3, Q9D616	Gene names	Psen2, Ad4h, Alg3, Ps-2, Psnl2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

CALB2_MOUSE
NC score	0.019113 (rank : 100)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CALB2_HUMAN
NC score	0.018757 (rank : 101)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	149	Shared Neighborhood Hits	14
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

RUSC2_MOUSE
NC score	0.018521 (rank : 102)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	305	Shared Neighborhood Hits	8
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

AKAP6_HUMAN
NC score	0.018116 (rank : 103)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

TP53B_MOUSE
NC score	0.017796 (rank : 104)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	644	Shared Neighborhood Hits	11
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DIDO1_HUMAN
NC score	0.016827 (rank : 105)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	960	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ZN318_HUMAN
NC score	0.016148 (rank : 106)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	497	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

NCOA7_HUMAN
NC score	0.015955 (rank : 107)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

K0423_HUMAN
NC score	0.014333 (rank : 108)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TM131_MOUSE
NC score	0.013520 (rank : 109)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

NOP14_MOUSE
NC score	0.012999 (rank : 110)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	324	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

BRDT_HUMAN
NC score	0.012755 (rank : 111)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

CCD47_HUMAN
NC score	0.012108 (rank : 112)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	7
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

FA86A_HUMAN
NC score	0.011396 (rank : 113)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G04, Q96S85	Gene names	FAM86A
Domain Architecture	No domain graphic available
Description	Protein FAM86A.

UBN1_HUMAN
NC score	0.011019 (rank : 114)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

CKLF4_MOUSE
NC score	0.011013 (rank : 115)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CJ61, Q8K143	Gene names	Cmtm4, Cklfsf4
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4).

DDX49_HUMAN
NC score	0.010862 (rank : 116)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

A16L1_MOUSE
NC score	0.010745 (rank : 117)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	776	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

CK5P2_HUMAN
NC score	0.010705 (rank : 118)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	1433	Shared Neighborhood Hits	29
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

DIAP2_HUMAN
NC score	0.010694 (rank : 119)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

PSMD2_MOUSE
NC score	0.010338 (rank : 120)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

MINT_MOUSE
NC score	0.009592 (rank : 121)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	1514	Shared Neighborhood Hits	19
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GOGA2_MOUSE
NC score	0.009495 (rank : 122)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	944	Shared Neighborhood Hits	22
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CKLF4_HUMAN
NC score	0.009455 (rank : 123)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZR5, Q8IZR4, Q8IZV1	Gene names	CMTM4, CKLFSF4
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4).

VIGLN_HUMAN
NC score	0.008787 (rank : 124)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

JHD3C_HUMAN
NC score	0.008263 (rank : 125)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

SYNE2_HUMAN
NC score	0.008135 (rank : 126)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	1323	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

HIP1R_MOUSE
NC score	0.007305 (rank : 127)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

DYSF_MOUSE
NC score	0.007133 (rank : 128)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DNJC8_MOUSE
NC score	0.006832 (rank : 129)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

DNJC8_HUMAN
NC score	0.006688 (rank : 130)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	380	Shared Neighborhood Hits	14
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

MY18A_HUMAN
NC score	0.006430 (rank : 131)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	1929	Shared Neighborhood Hits	36
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

AFAD_HUMAN
NC score	0.006402 (rank : 132)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	689	Shared Neighborhood Hits	23
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

A16L1_HUMAN
NC score	0.006019 (rank : 133)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	664	Shared Neighborhood Hits	17
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

GOGA4_HUMAN
NC score	0.005141 (rank : 134)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	2034	Shared Neighborhood Hits	35
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GNRP_HUMAN
NC score	0.005038 (rank : 135)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

HMMR_HUMAN
NC score	0.004692 (rank : 136)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	1082	Shared Neighborhood Hits	22
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

UBP1_HUMAN
NC score	0.004359 (rank : 137)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP8_HUMAN
NC score	0.004006 (rank : 138)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	751	Shared Neighborhood Hits	21
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CXA12_HUMAN
NC score	0.003811 (rank : 139)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T442, O43440, Q7Z7J2, Q8IWJ9	Gene names	GJA12
Domain Architecture	No domain graphic available
Description	Gap junction alpha-12 protein (Connexin-47) (Cx47) (Connexin-46.6) (Cx46.6).

GNRP_MOUSE
NC score	0.003094 (rank : 140)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ANR26_HUMAN
NC score	0.002792 (rank : 141)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	1614	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SSX3_HUMAN
NC score	0.002534 (rank : 142)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q99909, O60223, Q5JQZ3	Gene names	SSX3
Domain Architecture
Description	Protein SSX3.

MERL_MOUSE
NC score	0.002528 (rank : 143)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

RRBP1_MOUSE
NC score	0.002501 (rank : 144)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	1650	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CING_MOUSE
NC score	0.001761 (rank : 145)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	1432	Shared Neighborhood Hits	27
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

LAMC1_MOUSE
NC score	0.001076 (rank : 146)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	856	Shared Neighborhood Hits	15
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

STK10_HUMAN
NC score	0.000845 (rank : 147)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	1921	Shared Neighborhood Hits	29
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
NC score	0.000626 (rank : 148)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	2132	Shared Neighborhood Hits	34
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK39_HUMAN
NC score	-0.000968 (rank : 149)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	882	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

CHL1_MOUSE
NC score	-0.001032 (rank : 150)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

OLF9_MOUSE
NC score	-0.001379 (rank : 151)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	700	Shared Neighborhood Hits	9
SwissProt Accessions	Q60885, Q8VGC0	Gene names	Olfr9, Mor269-3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 9 (Olfactory receptor 269-3) (Odorant receptor M25).

GPR32_HUMAN
NC score	-0.001601 (rank : 152)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	O75388, Q6NWS5	Gene names	GPR32
Domain Architecture
Description	Probable G-protein coupled receptor 32.

MYO3B_HUMAN
NC score	-0.002508 (rank : 153)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	923	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

TCF17_MOUSE
NC score	-0.003708 (rank : 154)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	786	Shared Neighborhood Hits	6
SwissProt Accessions	Q61751	Gene names	Znf354a, Kid1, Tcf17, Zfp354a
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Renal transcription factor Kid-1) (Kidney, ischemia, and developmentally- regulated protein 1).

CTRO_MOUSE
NC score	-0.003963 (rank : 155)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	2344	Shared Neighborhood Hits	30
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ZBT16_HUMAN
NC score	-0.004328 (rank : 156)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	1010	Shared Neighborhood Hits	5
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZNF34_HUMAN
NC score	-0.004364 (rank : 157)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZ26	Gene names	ZNF34, KOX32
Domain Architecture	No domain graphic available
Description	Zinc finger protein 34 (Zinc finger protein KOX32).