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Network neighborhood for query Sequence : TRPC4_HUMAN

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TRPC4_HUMAN
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPC4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	140	Target Neighborhood Hits	140	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0 (rank : 2)	NC score	0.999606 (rank : 2)
Query Neighborhood Hits	140	Target Neighborhood Hits	141	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	0 (rank : 3)	NC score	0.990147 (rank : 4)
Query Neighborhood Hits	140	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	0 (rank : 4)	NC score	0.990570 (rank : 3)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC1_HUMAN
θ value	5.1754e-181 (rank : 5)	NC score	0.959276 (rank : 6)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	58
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	1.96665e-180 (rank : 6)	NC score	0.959458 (rank : 5)
Query Neighborhood Hits	140	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC3_HUMAN
θ value	1.85788e-146 (rank : 7)	NC score	0.947853 (rank : 9)
Query Neighborhood Hits	140	Target Neighborhood Hits	137	Shared Neighborhood Hits	77
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	5.40562e-146 (rank : 8)	NC score	0.949441 (rank : 7)
Query Neighborhood Hits	140	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_HUMAN
θ value	1.62758e-142 (rank : 9)	NC score	0.940328 (rank : 12)
Query Neighborhood Hits	140	Target Neighborhood Hits	171	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_HUMAN
θ value	4.00889e-141 (rank : 10)	NC score	0.939770 (rank : 13)
Query Neighborhood Hits	140	Target Neighborhood Hits	123	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	6.83811e-141 (rank : 11)	NC score	0.940575 (rank : 11)
Query Neighborhood Hits	140	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC6_MOUSE
θ value	1.1664e-140 (rank : 12)	NC score	0.942084 (rank : 10)
Query Neighborhood Hits	140	Target Neighborhood Hits	171	Shared Neighborhood Hits	77
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC2_MOUSE
θ value	1.53757e-108 (rank : 13)	NC score	0.948122 (rank : 8)
Query Neighborhood Hits	140	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPM8_HUMAN
θ value	3.39556e-23 (rank : 14)	NC score	0.590135 (rank : 15)
Query Neighborhood Hits	140	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
θ value	2.87452e-22 (rank : 15)	NC score	0.592624 (rank : 14)
Query Neighborhood Hits	140	Target Neighborhood Hits	58	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM7_MOUSE
θ value	6.20254e-17 (rank : 16)	NC score	0.496503 (rank : 17)
Query Neighborhood Hits	140	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
θ value	4.02038e-16 (rank : 17)	NC score	0.494015 (rank : 18)
Query Neighborhood Hits	140	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_MOUSE
θ value	5.25075e-16 (rank : 18)	NC score	0.487317 (rank : 19)
Query Neighborhood Hits	140	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_HUMAN
θ value	4.44505e-15 (rank : 19)	NC score	0.464440 (rank : 21)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM2_HUMAN
θ value	4.91457e-14 (rank : 20)	NC score	0.503932 (rank : 16)
Query Neighborhood Hits	140	Target Neighborhood Hits	64	Shared Neighborhood Hits	34
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
θ value	4.91457e-14 (rank : 21)	NC score	0.479442 (rank : 20)
Query Neighborhood Hits	140	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM3_HUMAN
θ value	5.43371e-13 (rank : 22)	NC score	0.418986 (rank : 22)
Query Neighborhood Hits	140	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV3_MOUSE
θ value	1.53129e-07 (rank : 23)	NC score	0.320433 (rank : 24)
Query Neighborhood Hits	140	Target Neighborhood Hits	188	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
θ value	4.45536e-07 (rank : 24)	NC score	0.339361 (rank : 23)
Query Neighborhood Hits	140	Target Neighborhood Hits	198	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV1_MOUSE
θ value	2.21117e-06 (rank : 25)	NC score	0.289959 (rank : 25)
Query Neighborhood Hits	140	Target Neighborhood Hits	189	Shared Neighborhood Hits	82
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
θ value	4.92598e-06 (rank : 26)	NC score	0.287413 (rank : 26)
Query Neighborhood Hits	140	Target Neighborhood Hits	184	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV5_MOUSE
θ value	0.00020696 (rank : 27)	NC score	0.249350 (rank : 27)
Query Neighborhood Hits	140	Target Neighborhood Hits	278	Shared Neighborhood Hits	97
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

PK2L1_HUMAN
θ value	0.000270298 (rank : 28)	NC score	0.238027 (rank : 30)
Query Neighborhood Hits	140	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PKD2_HUMAN
θ value	0.000270298 (rank : 29)	NC score	0.195181 (rank : 35)
Query Neighborhood Hits	140	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PK2L2_HUMAN
θ value	0.00102713 (rank : 30)	NC score	0.176229 (rank : 39)
Query Neighborhood Hits	140	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV2_HUMAN
θ value	0.00102713 (rank : 31)	NC score	0.191411 (rank : 38)
Query Neighborhood Hits	140	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PKD2_MOUSE
θ value	0.00134147 (rank : 32)	NC score	0.194228 (rank : 36)
Query Neighborhood Hits	140	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

TRPV6_HUMAN
θ value	0.00298849 (rank : 33)	NC score	0.242584 (rank : 28)
Query Neighborhood Hits	140	Target Neighborhood Hits	262	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV2_MOUSE
θ value	0.00665767 (rank : 34)	NC score	0.193761 (rank : 37)
Query Neighborhood Hits	140	Target Neighborhood Hits	111	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV6_MOUSE
θ value	0.00665767 (rank : 35)	NC score	0.232660 (rank : 31)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	97
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

PK2L2_MOUSE
θ value	0.0113563 (rank : 36)	NC score	0.207212 (rank : 34)
Query Neighborhood Hits	140	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV5_HUMAN
θ value	0.0113563 (rank : 37)	NC score	0.215779 (rank : 33)
Query Neighborhood Hits	140	Target Neighborhood Hits	261	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

CAC1B_HUMAN
θ value	0.0330416 (rank : 38)	NC score	0.055443 (rank : 114)
Query Neighborhood Hits	140	Target Neighborhood Hits	257	Shared Neighborhood Hits	27
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0.0330416 (rank : 39)	NC score	0.051947 (rank : 142)
Query Neighborhood Hits	140	Target Neighborhood Hits	351	Shared Neighborhood Hits	26
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRPV4_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.241309 (rank : 29)
Query Neighborhood Hits	140	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

EHMT2_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.080270 (rank : 65)
Query Neighborhood Hits	140	Target Neighborhood Hits	498	Shared Neighborhood Hits	80
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

AN36B_HUMAN
θ value	0.0736092 (rank : 42)	NC score	0.097821 (rank : 45)
Query Neighborhood Hits	140	Target Neighborhood Hits	294	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

RN5A_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.093978 (rank : 47)
Query Neighborhood Hits	140	Target Neighborhood Hits	608	Shared Neighborhood Hits	76
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

TNKS2_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.081046 (rank : 62)
Query Neighborhood Hits	140	Target Neighborhood Hits	361	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TRPV4_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.223589 (rank : 32)
Query Neighborhood Hits	140	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ASB15_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.067968 (rank : 90)
Query Neighborhood Hits	140	Target Neighborhood Hits	305	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

PCDGC_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.009566 (rank : 181)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	O60330, O15100, Q6UW70, Q9Y5D7	Gene names	PCDHGA12, CDH21, FIB3, KIAA0588
Domain Architecture
Description	Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin 3).

ASZ1_MOUSE
θ value	0.21417 (rank : 48)	NC score	0.079705 (rank : 67)
Query Neighborhood Hits	140	Target Neighborhood Hits	319	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

EHMT1_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.092753 (rank : 48)
Query Neighborhood Hits	140	Target Neighborhood Hits	417	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

RN5A_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.088950 (rank : 54)
Query Neighborhood Hits	140	Target Neighborhood Hits	899	Shared Neighborhood Hits	85
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SCN4A_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.046856 (rank : 156)
Query Neighborhood Hits	140	Target Neighborhood Hits	133	Shared Neighborhood Hits	29
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

ANKY2_MOUSE
θ value	0.279714 (rank : 52)	NC score	0.115659 (rank : 40)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	72
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

POTE8_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.087261 (rank : 56)
Query Neighborhood Hits	140	Target Neighborhood Hits	337	Shared Neighborhood Hits	80
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

TNKS1_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.084214 (rank : 59)
Query Neighborhood Hits	140	Target Neighborhood Hits	477	Shared Neighborhood Hits	84
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANKK1_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.041254 (rank : 164)
Query Neighborhood Hits	140	Target Neighborhood Hits	1075	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR18_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.053983 (rank : 124)
Query Neighborhood Hits	140	Target Neighborhood Hits	1106	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASZ1_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.072848 (rank : 76)
Query Neighborhood Hits	140	Target Neighborhood Hits	341	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANK1_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.110635 (rank : 41)
Query Neighborhood Hits	140	Target Neighborhood Hits	416	Shared Neighborhood Hits	87
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.110416 (rank : 43)
Query Neighborhood Hits	140	Target Neighborhood Hits	430	Shared Neighborhood Hits	86
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

CTTB2_HUMAN
θ value	0.47712 (rank : 60)	NC score	0.086574 (rank : 57)
Query Neighborhood Hits	140	Target Neighborhood Hits	1061	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

MPP10_MOUSE
θ value	0.47712 (rank : 61)	NC score	0.031948 (rank : 169)
Query Neighborhood Hits	140	Target Neighborhood Hits	251	Shared Neighborhood Hits	13
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

PCDG7_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.007995 (rank : 184)
Query Neighborhood Hits	140	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5G6, Q9Y5D0	Gene names	PCDHGA7
Domain Architecture
Description	Protocadherin gamma A7 precursor (PCDH-gamma-A7).

ACBD6_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.110432 (rank : 42)
Query Neighborhood Hits	140	Target Neighborhood Hits	305	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANK3_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.088208 (rank : 55)
Query Neighborhood Hits	140	Target Neighborhood Hits	853	Shared Neighborhood Hits	90
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CSKI1_MOUSE
θ value	0.62314 (rank : 65)	NC score	0.065062 (rank : 97)
Query Neighborhood Hits	140	Target Neighborhood Hits	1031	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SC10A_MOUSE
θ value	0.62314 (rank : 66)	NC score	0.049368 (rank : 155)
Query Neighborhood Hits	140	Target Neighborhood Hits	107	Shared Neighborhood Hits	31
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

ANKR7_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.076149 (rank : 71)
Query Neighborhood Hits	140	Target Neighborhood Hits	286	Shared Neighborhood Hits	74
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR19_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.063050 (rank : 100)
Query Neighborhood Hits	140	Target Neighborhood Hits	276	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR44_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.082537 (rank : 61)
Query Neighborhood Hits	140	Target Neighborhood Hits	318	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR52_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.091620 (rank : 50)
Query Neighborhood Hits	140	Target Neighborhood Hits	322	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.091430 (rank : 51)
Query Neighborhood Hits	140	Target Neighborhood Hits	318	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

CSKI1_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.064793 (rank : 98)
Query Neighborhood Hits	140	Target Neighborhood Hits	997	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PCDGB_HUMAN
θ value	0.813845 (rank : 73)	NC score	0.008936 (rank : 182)
Query Neighborhood Hits	140	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5H2, Q9Y5D8, Q9Y5D9	Gene names	PCDHGA11
Domain Architecture
Description	Protocadherin gamma A11 precursor (PCDH-gamma-A11).

POT15_HUMAN
θ value	0.813845 (rank : 74)	NC score	0.077974 (rank : 69)
Query Neighborhood Hits	140	Target Neighborhood Hits	893	Shared Neighborhood Hits	82
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TR143_MOUSE
θ value	0.813845 (rank : 75)	NC score	0.026103 (rank : 171)
Query Neighborhood Hits	140	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQB9, Q2NL43	Gene names	Tas2r143, T2r36, Tas2r43
Domain Architecture
Description	Taste receptor type 2 member 143 (T2R143) (Taste receptor type 2 member 43) (T2R43) (mT2R36).

ANK2_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.074263 (rank : 72)
Query Neighborhood Hits	140	Target Neighborhood Hits	1615	Shared Neighborhood Hits	95
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR21_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.079884 (rank : 66)
Query Neighborhood Hits	140	Target Neighborhood Hits	864	Shared Neighborhood Hits	83
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT14_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.069849 (rank : 83)
Query Neighborhood Hits	140	Target Neighborhood Hits	403	Shared Neighborhood Hits	72
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

SC10A_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.051671 (rank : 145)
Query Neighborhood Hits	140	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CP250_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.004000 (rank : 189)
Query Neighborhood Hits	140	Target Neighborhood Hits	1805	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CT026_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.043068 (rank : 159)
Query Neighborhood Hits	140	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

NET4_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.007054 (rank : 185)
Query Neighborhood Hits	140	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NFKB2_MOUSE
θ value	1.38821 (rank : 83)	NC score	0.053746 (rank : 126)
Query Neighborhood Hits	140	Target Neighborhood Hits	326	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

SCN8A_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.041901 (rank : 162)
Query Neighborhood Hits	140	Target Neighborhood Hits	135	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.043550 (rank : 158)
Query Neighborhood Hits	140	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

ANR28_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.069572 (rank : 85)
Query Neighborhood Hits	140	Target Neighborhood Hits	314	Shared Neighborhood Hits	79
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB15_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.059516 (rank : 110)
Query Neighborhood Hits	140	Target Neighborhood Hits	292	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB1_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.067045 (rank : 92)
Query Neighborhood Hits	140	Target Neighborhood Hits	470	Shared Neighborhood Hits	80
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.067151 (rank : 91)
Query Neighborhood Hits	140	Target Neighborhood Hits	471	Shared Neighborhood Hits	80
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

AN13A_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.068589 (rank : 87)
Query Neighborhood Hits	140	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

AN30A_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.051687 (rank : 143)
Query Neighborhood Hits	140	Target Neighborhood Hits	1119	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKY2_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.092289 (rank : 49)
Query Neighborhood Hits	140	Target Neighborhood Hits	306	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

CAC1E_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.042916 (rank : 160)
Query Neighborhood Hits	140	Target Neighborhood Hits	167	Shared Neighborhood Hits	26
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

PRDM2_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.001012 (rank : 195)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	8
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RYR2_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.017735 (rank : 175)
Query Neighborhood Hits	140	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

ANKK1_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.036062 (rank : 167)
Query Neighborhood Hits	140	Target Neighborhood Hits	1072	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR28_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.068193 (rank : 89)
Query Neighborhood Hits	140	Target Neighborhood Hits	314	Shared Neighborhood Hits	79
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANFY1_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.074033 (rank : 73)
Query Neighborhood Hits	140	Target Neighborhood Hits	480	Shared Neighborhood Hits	84
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR15_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.069587 (rank : 84)
Query Neighborhood Hits	140	Target Neighborhood Hits	478	Shared Neighborhood Hits	81
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ASB1_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.072806 (rank : 77)
Query Neighborhood Hits	140	Target Neighborhood Hits	292	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CAC1E_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.041955 (rank : 161)
Query Neighborhood Hits	140	Target Neighborhood Hits	148	Shared Neighborhood Hits	22
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CDC37_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.016075 (rank : 177)
Query Neighborhood Hits	140	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDC37_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.018347 (rank : 174)
Query Neighborhood Hits	140	Target Neighborhood Hits	359	Shared Neighborhood Hits	11
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

RBBP8_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.011347 (rank : 180)
Query Neighborhood Hits	140	Target Neighborhood Hits	476	Shared Neighborhood Hits	13
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

TRPA1_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.097230 (rank : 46)
Query Neighborhood Hits	140	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

VPS18_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.017024 (rank : 176)
Query Neighborhood Hits	140	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R307, Q8BGV6, Q8BZX6, Q8C126	Gene names	Vps18
Domain Architecture
Description	Vacuolar protein sorting-associated protein 18.

ANR26_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.057915 (rank : 111)
Query Neighborhood Hits	140	Target Neighborhood Hits	1614	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CTNS_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.019310 (rank : 173)
Query Neighborhood Hits	140	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P57757	Gene names	Ctns
Domain Architecture
Description	Cystinosin.

FANK1_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.062021 (rank : 104)
Query Neighborhood Hits	140	Target Neighborhood Hits	326	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

RIMS1_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.003713 (rank : 192)
Query Neighborhood Hits	140	Target Neighborhood Hits	437	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SCN5A_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.045170 (rank : 157)
Query Neighborhood Hits	140	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SYCP1_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.008395 (rank : 183)
Query Neighborhood Hits	140	Target Neighborhood Hits	1313	Shared Neighborhood Hits	29
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRPA1_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.105574 (rank : 44)
Query Neighborhood Hits	140	Target Neighborhood Hits	339	Shared Neighborhood Hits	93
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

UACA_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.038705 (rank : 165)
Query Neighborhood Hits	140	Target Neighborhood Hits	1622	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ACBD6_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.086252 (rank : 58)
Query Neighborhood Hits	140	Target Neighborhood Hits	304	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

AN36A_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.059981 (rank : 108)
Query Neighborhood Hits	140	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANKS1_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.090567 (rank : 52)
Query Neighborhood Hits	140	Target Neighborhood Hits	438	Shared Neighborhood Hits	81
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS6_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.078460 (rank : 68)
Query Neighborhood Hits	140	Target Neighborhood Hits	411	Shared Neighborhood Hits	78
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB3_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.089413 (rank : 53)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

BCL3_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.064126 (rank : 99)
Query Neighborhood Hits	140	Target Neighborhood Hits	324	Shared Neighborhood Hits	77
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

CAC1A_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.034900 (rank : 168)
Query Neighborhood Hits	140	Target Neighborhood Hits	387	Shared Neighborhood Hits	23
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.036212 (rank : 166)
Query Neighborhood Hits	140	Target Neighborhood Hits	267	Shared Neighborhood Hits	22
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CLPB_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.050937 (rank : 150)
Query Neighborhood Hits	140	Target Neighborhood Hits	265	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

DOPO_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.011835 (rank : 179)
Query Neighborhood Hits	140	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P09172, Q5T381, Q96AG2	Gene names	DBH
Domain Architecture
Description	Dopamine beta-hydroxylase precursor (EC 1.14.17.1) (Dopamine beta- monooxygenase).

EEA1_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.003836 (rank : 191)
Query Neighborhood Hits	140	Target Neighborhood Hits	1796	Shared Neighborhood Hits	36
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

K0831_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.006916 (rank : 186)
Query Neighborhood Hits	140	Target Neighborhood Hits	277	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

LZTS2_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.006802 (rank : 187)
Query Neighborhood Hits	140	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

NUMA1_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.003992 (rank : 190)
Query Neighborhood Hits	140	Target Neighborhood Hits	1523	Shared Neighborhood Hits	26
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PSD10_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.053686 (rank : 127)
Query Neighborhood Hits	140	Target Neighborhood Hits	301	Shared Neighborhood Hits	72
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

SYNE1_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.003557 (rank : 193)
Query Neighborhood Hits	140	Target Neighborhood Hits	1484	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

AKA12_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.005238 (rank : 188)
Query Neighborhood Hits	140	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ANKF1_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.019733 (rank : 172)
Query Neighborhood Hits	140	Target Neighborhood Hits	126	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKS1_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.083908 (rank : 60)
Query Neighborhood Hits	140	Target Neighborhood Hits	453	Shared Neighborhood Hits	75
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ASB17_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.012271 (rank : 178)
Query Neighborhood Hits	140	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHP9, Q9CUF9	Gene names	Asb17
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 17 (ASB-17).

BCOR_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.071070 (rank : 82)
Query Neighborhood Hits	140	Target Neighborhood Hits	609	Shared Neighborhood Hits	77
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.072300 (rank : 80)
Query Neighborhood Hits	140	Target Neighborhood Hits	521	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CAC1H_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.027609 (rank : 170)
Query Neighborhood Hits	140	Target Neighborhood Hits	307	Shared Neighborhood Hits	22
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

RIPK4_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.041723 (rank : 163)
Query Neighborhood Hits	140	Target Neighborhood Hits	1094	Shared Neighborhood Hits	81
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

SLK_HUMAN
θ value	8.99809 (rank : 139)	NC score	-0.003605 (rank : 196)
Query Neighborhood Hits	140	Target Neighborhood Hits	1775	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TIF1G_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.002161 (rank : 194)
Query Neighborhood Hits	140	Target Neighborhood Hits	498	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ANFY1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.054859 (rank : 117)
Query Neighborhood Hits	140	Target Neighborhood Hits	480	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKR1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.053486 (rank : 129)
Query Neighborhood Hits	140	Target Neighborhood Hits	308	Shared Neighborhood Hits	69
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.068282 (rank : 88)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR2_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.052575 (rank : 139)
Query Neighborhood Hits	140	Target Neighborhood Hits	321	Shared Neighborhood Hits	69
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANKR2_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.051685 (rank : 144)
Query Neighborhood Hits	140	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR6_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.055061 (rank : 115)
Query Neighborhood Hits	140	Target Neighborhood Hits	439	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANKS6_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.072913 (rank : 75)
Query Neighborhood Hits	140	Target Neighborhood Hits	435	Shared Neighborhood Hits	79
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR16_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.053067 (rank : 135)
Query Neighborhood Hits	140	Target Neighborhood Hits	286	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR22_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.050689 (rank : 151)
Query Neighborhood Hits	140	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR25_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.053147 (rank : 133)
Query Neighborhood Hits	140	Target Neighborhood Hits	398	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR29_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.072690 (rank : 78)
Query Neighborhood Hits	140	Target Neighborhood Hits	294	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR32_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.053103 (rank : 134)
Query Neighborhood Hits	140	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR35_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.065347 (rank : 95)
Query Neighborhood Hits	140	Target Neighborhood Hits	784	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANR46_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.050958 (rank : 149)
Query Neighborhood Hits	140	Target Neighborhood Hits	281	Shared Neighborhood Hits	70
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR49_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.051164 (rank : 147)
Query Neighborhood Hits	140	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR50_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.080476 (rank : 63)
Query Neighborhood Hits	140	Target Neighborhood Hits	361	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANRA2_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.052912 (rank : 136)
Query Neighborhood Hits	140	Target Neighborhood Hits	288	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.053271 (rank : 131)
Query Neighborhood Hits	140	Target Neighborhood Hits	287	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB14_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.056444 (rank : 113)
Query Neighborhood Hits	140	Target Neighborhood Hits	293	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.062307 (rank : 103)
Query Neighborhood Hits	140	Target Neighborhood Hits	291	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.065944 (rank : 94)
Query Neighborhood Hits	140	Target Neighborhood Hits	309	Shared Neighborhood Hits	74
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB2_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.062339 (rank : 102)
Query Neighborhood Hits	140	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.080434 (rank : 64)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB6_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.053176 (rank : 132)
Query Neighborhood Hits	140	Target Neighborhood Hits	256	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.052272 (rank : 141)
Query Neighborhood Hits	140	Target Neighborhood Hits	264	Shared Neighborhood Hits	70
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB7_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.054285 (rank : 121)
Query Neighborhood Hits	140	Target Neighborhood Hits	296	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.054247 (rank : 122)
Query Neighborhood Hits	140	Target Neighborhood Hits	296	Shared Neighborhood Hits	68
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB8_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.050540 (rank : 152)
Query Neighborhood Hits	140	Target Neighborhood Hits	294	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BARD1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.065328 (rank : 96)
Query Neighborhood Hits	140	Target Neighborhood Hits	427	Shared Neighborhood Hits	74
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.077560 (rank : 70)
Query Neighborhood Hits	140	Target Neighborhood Hits	411	Shared Neighborhood Hits	74
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BCL3_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.054462 (rank : 118)
Query Neighborhood Hits	140	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CSKI2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.073149 (rank : 74)
Query Neighborhood Hits	140	Target Neighborhood Hits	747	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.072270 (rank : 81)
Query Neighborhood Hits	140	Target Neighborhood Hits	812	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT012_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.056796 (rank : 112)
Query Neighborhood Hits	140	Target Neighborhood Hits	229	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

EF2K_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.050527 (rank : 153)
Query Neighborhood Hits	140	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.052500 (rank : 140)
Query Neighborhood Hits	140	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EHMT2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.066860 (rank : 93)
Query Neighborhood Hits	140	Target Neighborhood Hits	750	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FANK1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.054353 (rank : 119)
Query Neighborhood Hits	140	Target Neighborhood Hits	325	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

GABP2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.068961 (rank : 86)
Query Neighborhood Hits	140	Target Neighborhood Hits	454	Shared Neighborhood Hits	75
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.072309 (rank : 79)
Query Neighborhood Hits	140	Target Neighborhood Hits	429	Shared Neighborhood Hits	75
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

IKBA_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.052761 (rank : 137)
Query Neighborhood Hits	140	Target Neighborhood Hits	280	Shared Neighborhood Hits	72
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBA_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.052643 (rank : 138)
Query Neighborhood Hits	140	Target Neighborhood Hits	283	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IKBB_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.051348 (rank : 146)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.051004 (rank : 148)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	72
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

IKBE_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.053429 (rank : 130)
Query Neighborhood Hits	140	Target Neighborhood Hits	308	Shared Neighborhood Hits	72
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

INVS_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.061928 (rank : 105)
Query Neighborhood Hits	140	Target Neighborhood Hits	455	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.062775 (rank : 101)
Query Neighborhood Hits	140	Target Neighborhood Hits	609	Shared Neighborhood Hits	79
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MIB2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.053922 (rank : 125)
Query Neighborhood Hits	140	Target Neighborhood Hits	438	Shared Neighborhood Hits	73
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.053506 (rank : 128)
Query Neighborhood Hits	140	Target Neighborhood Hits	409	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MPP8_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.054300 (rank : 120)
Query Neighborhood Hits	140	Target Neighborhood Hits	948	Shared Neighborhood Hits	77
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYPT2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.059688 (rank : 109)
Query Neighborhood Hits	140	Target Neighborhood Hits	707	Shared Neighborhood Hits	79
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PA2G6_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.054227 (rank : 123)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.061136 (rank : 107)
Query Neighborhood Hits	140	Target Neighborhood Hits	293	Shared Neighborhood Hits	77
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

POT22_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.054919 (rank : 116)
Query Neighborhood Hits	140	Target Neighborhood Hits	266	Shared Neighborhood Hits	63
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

PSD10_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.050305 (rank : 154)
Query Neighborhood Hits	140	Target Neighborhood Hits	293	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RAI14_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.061145 (rank : 106)
Query Neighborhood Hits	140	Target Neighborhood Hits	1367	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

Hits sorted by NC score

TRPC4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	140	Target Neighborhood Hits	140	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.999606 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	140	Target Neighborhood Hits	141	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.990570 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.990147 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	140	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC1_MOUSE
NC score	0.959458 (rank : 5)	θ value	1.96665e-180 (rank : 6)
Query Neighborhood Hits	140	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.959276 (rank : 6)	θ value	5.1754e-181 (rank : 5)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	58
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC3_MOUSE
NC score	0.949441 (rank : 7)	θ value	5.40562e-146 (rank : 8)
Query Neighborhood Hits	140	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC2_MOUSE
NC score	0.948122 (rank : 8)	θ value	1.53757e-108 (rank : 13)
Query Neighborhood Hits	140	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_HUMAN
NC score	0.947853 (rank : 9)	θ value	1.85788e-146 (rank : 7)
Query Neighborhood Hits	140	Target Neighborhood Hits	137	Shared Neighborhood Hits	77
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.942084 (rank : 10)	θ value	1.1664e-140 (rank : 12)
Query Neighborhood Hits	140	Target Neighborhood Hits	171	Shared Neighborhood Hits	77
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_MOUSE
NC score	0.940575 (rank : 11)	θ value	6.83811e-141 (rank : 11)
Query Neighborhood Hits	140	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC6_HUMAN
NC score	0.940328 (rank : 12)	θ value	1.62758e-142 (rank : 9)
Query Neighborhood Hits	140	Target Neighborhood Hits	171	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_HUMAN
NC score	0.939770 (rank : 13)	θ value	4.00889e-141 (rank : 10)
Query Neighborhood Hits	140	Target Neighborhood Hits	123	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPM8_MOUSE
NC score	0.592624 (rank : 14)	θ value	2.87452e-22 (rank : 15)
Query Neighborhood Hits	140	Target Neighborhood Hits	58	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
NC score	0.590135 (rank : 15)	θ value	3.39556e-23 (rank : 14)
Query Neighborhood Hits	140	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_HUMAN
NC score	0.503932 (rank : 16)	θ value	4.91457e-14 (rank : 20)
Query Neighborhood Hits	140	Target Neighborhood Hits	64	Shared Neighborhood Hits	34
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM7_MOUSE
NC score	0.496503 (rank : 17)	θ value	6.20254e-17 (rank : 16)
Query Neighborhood Hits	140	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
NC score	0.494015 (rank : 18)	θ value	4.02038e-16 (rank : 17)
Query Neighborhood Hits	140	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_MOUSE
NC score	0.487317 (rank : 19)	θ value	5.25075e-16 (rank : 18)
Query Neighborhood Hits	140	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM2_MOUSE
NC score	0.479442 (rank : 20)	θ value	4.91457e-14 (rank : 21)
Query Neighborhood Hits	140	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM6_HUMAN
NC score	0.464440 (rank : 21)	θ value	4.44505e-15 (rank : 19)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM3_HUMAN
NC score	0.418986 (rank : 22)	θ value	5.43371e-13 (rank : 22)
Query Neighborhood Hits	140	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV3_HUMAN
NC score	0.339361 (rank : 23)	θ value	4.45536e-07 (rank : 24)
Query Neighborhood Hits	140	Target Neighborhood Hits	198	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.320433 (rank : 24)	θ value	1.53129e-07 (rank : 23)
Query Neighborhood Hits	140	Target Neighborhood Hits	188	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_MOUSE
NC score	0.289959 (rank : 25)	θ value	2.21117e-06 (rank : 25)
Query Neighborhood Hits	140	Target Neighborhood Hits	189	Shared Neighborhood Hits	82
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
NC score	0.287413 (rank : 26)	θ value	4.92598e-06 (rank : 26)
Query Neighborhood Hits	140	Target Neighborhood Hits	184	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV5_MOUSE
NC score	0.249350 (rank : 27)	θ value	0.00020696 (rank : 27)
Query Neighborhood Hits	140	Target Neighborhood Hits	278	Shared Neighborhood Hits	97
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
NC score	0.242584 (rank : 28)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	140	Target Neighborhood Hits	262	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV4_HUMAN
NC score	0.241309 (rank : 29)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	140	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

PK2L1_HUMAN
NC score	0.238027 (rank : 30)	θ value	0.000270298 (rank : 28)
Query Neighborhood Hits	140	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPV6_MOUSE
NC score	0.232660 (rank : 31)	θ value	0.00665767 (rank : 35)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	97
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV4_MOUSE
NC score	0.223589 (rank : 32)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	140	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_HUMAN
NC score	0.215779 (rank : 33)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	140	Target Neighborhood Hits	261	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

PK2L2_MOUSE
NC score	0.207212 (rank : 34)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	140	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
NC score	0.195181 (rank : 35)	θ value	0.000270298 (rank : 29)
Query Neighborhood Hits	140	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
NC score	0.194228 (rank : 36)	θ value	0.00134147 (rank : 32)
Query Neighborhood Hits	140	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

TRPV2_MOUSE
NC score	0.193761 (rank : 37)	θ value	0.00665767 (rank : 34)
Query Neighborhood Hits	140	Target Neighborhood Hits	111	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV2_HUMAN
NC score	0.191411 (rank : 38)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	140	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PK2L2_HUMAN
NC score	0.176229 (rank : 39)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	140	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

ANKY2_MOUSE
NC score	0.115659 (rank : 40)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	72
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANK1_HUMAN
NC score	0.110635 (rank : 41)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	140	Target Neighborhood Hits	416	Shared Neighborhood Hits	87
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ACBD6_MOUSE
NC score	0.110432 (rank : 42)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	140	Target Neighborhood Hits	305	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANK1_MOUSE
NC score	0.110416 (rank : 43)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	140	Target Neighborhood Hits	430	Shared Neighborhood Hits	86
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

TRPA1_HUMAN
NC score	0.105574 (rank : 44)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	140	Target Neighborhood Hits	339	Shared Neighborhood Hits	93
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

AN36B_HUMAN
NC score	0.097821 (rank : 45)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	140	Target Neighborhood Hits	294	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

TRPA1_MOUSE
NC score	0.097230 (rank : 46)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	140	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

RN5A_HUMAN
NC score	0.093978 (rank : 47)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	140	Target Neighborhood Hits	608	Shared Neighborhood Hits	76
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

EHMT1_HUMAN
NC score	0.092753 (rank : 48)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	140	Target Neighborhood Hits	417	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANKY2_HUMAN
NC score	0.092289 (rank : 49)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	140	Target Neighborhood Hits	306	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR52_HUMAN
NC score	0.091620 (rank : 50)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	140	Target Neighborhood Hits	322	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
NC score	0.091430 (rank : 51)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	140	Target Neighborhood Hits	318	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANKS1_HUMAN
NC score	0.090567 (rank : 52)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	140	Target Neighborhood Hits	438	Shared Neighborhood Hits	81
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB3_HUMAN
NC score	0.089413 (rank : 53)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

RN5A_MOUSE
NC score	0.088950 (rank : 54)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	140	Target Neighborhood Hits	899	Shared Neighborhood Hits	85
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANK3_HUMAN
NC score	0.088208 (rank : 55)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	140	Target Neighborhood Hits	853	Shared Neighborhood Hits	90
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

POTE8_HUMAN
NC score	0.087261 (rank : 56)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	140	Target Neighborhood Hits	337	Shared Neighborhood Hits	80
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

CTTB2_HUMAN
NC score	0.086574 (rank : 57)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	140	Target Neighborhood Hits	1061	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ACBD6_HUMAN
NC score	0.086252 (rank : 58)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	140	Target Neighborhood Hits	304	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

TNKS1_HUMAN
NC score	0.084214 (rank : 59)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	140	Target Neighborhood Hits	477	Shared Neighborhood Hits	84
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANKS1_MOUSE
NC score	0.083908 (rank : 60)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	140	Target Neighborhood Hits	453	Shared Neighborhood Hits	75
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR44_HUMAN
NC score	0.082537 (rank : 61)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	140	Target Neighborhood Hits	318	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

TNKS2_HUMAN
NC score	0.081046 (rank : 62)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	140	Target Neighborhood Hits	361	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR50_HUMAN
NC score	0.080476 (rank : 63)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	140	Target Neighborhood Hits	361	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ASB3_MOUSE
NC score	0.080434 (rank : 64)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

EHMT2_HUMAN
NC score	0.080270 (rank : 65)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	140	Target Neighborhood Hits	498	Shared Neighborhood Hits	80
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR21_HUMAN
NC score	0.079884 (rank : 66)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	140	Target Neighborhood Hits	864	Shared Neighborhood Hits	83
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASZ1_MOUSE
NC score	0.079705 (rank : 67)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	140	Target Neighborhood Hits	319	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKS6_HUMAN
NC score	0.078460 (rank : 68)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	140	Target Neighborhood Hits	411	Shared Neighborhood Hits	78
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

POT15_HUMAN
NC score	0.077974 (rank : 69)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	140	Target Neighborhood Hits	893	Shared Neighborhood Hits	82
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

BARD1_MOUSE
NC score	0.077560 (rank : 70)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	140	Target Neighborhood Hits	411	Shared Neighborhood Hits	74
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANKR7_HUMAN
NC score	0.076149 (rank : 71)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	140	Target Neighborhood Hits	286	Shared Neighborhood Hits	74
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANK2_HUMAN
NC score	0.074263 (rank : 72)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	140	Target Neighborhood Hits	1615	Shared Neighborhood Hits	95
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANFY1_MOUSE
NC score	0.074033 (rank : 73)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	140	Target Neighborhood Hits	480	Shared Neighborhood Hits	84
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

CSKI2_HUMAN
NC score	0.073149 (rank : 74)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	140	Target Neighborhood Hits	747	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS6_MOUSE
NC score	0.072913 (rank : 75)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	140	Target Neighborhood Hits	435	Shared Neighborhood Hits	79
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASZ1_HUMAN
NC score	0.072848 (rank : 76)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	140	Target Neighborhood Hits	341	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB1_MOUSE
NC score	0.072806 (rank : 77)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	140	Target Neighborhood Hits	292	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR29_HUMAN
NC score	0.072690 (rank : 78)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	140	Target Neighborhood Hits	294	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

GABP2_MOUSE
NC score	0.072309 (rank : 79)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	140	Target Neighborhood Hits	429	Shared Neighborhood Hits	75
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

BCOR_MOUSE
NC score	0.072300 (rank : 80)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	140	Target Neighborhood Hits	521	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CSKI2_MOUSE
NC score	0.072270 (rank : 81)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	140	Target Neighborhood Hits	812	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

BCOR_HUMAN
NC score	0.071070 (rank : 82)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	140	Target Neighborhood Hits	609	Shared Neighborhood Hits	77
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

POT14_HUMAN
NC score	0.069849 (rank : 83)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	140	Target Neighborhood Hits	403	Shared Neighborhood Hits	72
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR15_HUMAN
NC score	0.069587 (rank : 84)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	140	Target Neighborhood Hits	478	Shared Neighborhood Hits	81
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR28_MOUSE
NC score	0.069572 (rank : 85)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	140	Target Neighborhood Hits	314	Shared Neighborhood Hits	79
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

GABP2_HUMAN
NC score	0.068961 (rank : 86)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	140	Target Neighborhood Hits	454	Shared Neighborhood Hits	75
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

AN13A_HUMAN
NC score	0.068589 (rank : 87)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	140	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANKR1_MOUSE
NC score	0.068282 (rank : 88)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	140	Target Neighborhood Hits	316	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANR28_HUMAN
NC score	0.068193 (rank : 89)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	140	Target Neighborhood Hits	314	Shared Neighborhood Hits	79
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB15_HUMAN
NC score	0.067968 (rank : 90)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	140	Target Neighborhood Hits	305	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB1_MOUSE
NC score	0.067151 (rank : 91)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	140	Target Neighborhood Hits	471	Shared Neighborhood Hits	80
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.067045 (rank : 92)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	140	Target Neighborhood Hits	470	Shared Neighborhood Hits	80
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

EHMT2_MOUSE
NC score	0.066860 (rank : 93)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	140	Target Neighborhood Hits	750	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB2_HUMAN
NC score	0.065944 (rank : 94)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	140	Target Neighborhood Hits	309	Shared Neighborhood Hits	74
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR35_HUMAN
NC score	0.065347 (rank : 95)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	140	Target Neighborhood Hits	784	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

BARD1_HUMAN
NC score	0.065328 (rank : 96)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	140	Target Neighborhood Hits	427	Shared Neighborhood Hits	74
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CSKI1_MOUSE
NC score	0.065062 (rank : 97)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	140	Target Neighborhood Hits	1031	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_HUMAN
NC score	0.064793 (rank : 98)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	140	Target Neighborhood Hits	997	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

BCL3_HUMAN
NC score	0.064126 (rank : 99)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	140	Target Neighborhood Hits	324	Shared Neighborhood Hits	77
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANR19_HUMAN
NC score	0.063050 (rank : 100)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	140	Target Neighborhood Hits	276	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

INVS_MOUSE
NC score	0.062775 (rank : 101)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	140	Target Neighborhood Hits	609	Shared Neighborhood Hits	79
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB2_MOUSE
NC score	0.062339 (rank : 102)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	140	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB1_HUMAN
NC score	0.062307 (rank : 103)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	140	Target Neighborhood Hits	291	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

FANK1_HUMAN
NC score	0.062021 (rank : 104)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	140	Target Neighborhood Hits	326	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

INVS_HUMAN
NC score	0.061928 (rank : 105)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	140	Target Neighborhood Hits	455	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

RAI14_HUMAN
NC score	0.061145 (rank : 106)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	140	Target Neighborhood Hits	1367	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

PA2G6_MOUSE
NC score	0.061136 (rank : 107)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	140	Target Neighborhood Hits	293	Shared Neighborhood Hits	77
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

AN36A_HUMAN
NC score	0.059981 (rank : 108)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	140	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

MYPT2_HUMAN
NC score	0.059688 (rank : 109)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	140	Target Neighborhood Hits	707	Shared Neighborhood Hits	79
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB15_MOUSE
NC score	0.059516 (rank : 110)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	140	Target Neighborhood Hits	292	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR26_HUMAN
NC score	0.057915 (rank : 111)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	140	Target Neighborhood Hits	1614	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CT012_MOUSE
NC score	0.056796 (rank : 112)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	140	Target Neighborhood Hits	229	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

ASB14_MOUSE
NC score	0.056444 (rank : 113)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	140	Target Neighborhood Hits	293	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CAC1B_HUMAN
NC score	0.055443 (rank : 114)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	140	Target Neighborhood Hits	257	Shared Neighborhood Hits	27
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ANKR6_HUMAN
NC score	0.055061 (rank : 115)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	140	Target Neighborhood Hits	439	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

POT22_HUMAN
NC score	0.054919 (rank : 116)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	140	Target Neighborhood Hits	266	Shared Neighborhood Hits	63
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANFY1_HUMAN
NC score	0.054859 (rank : 117)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	140	Target Neighborhood Hits	480	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BCL3_MOUSE
NC score	0.054462 (rank : 118)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	140	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

FANK1_MOUSE
NC score	0.054353 (rank : 119)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	140	Target Neighborhood Hits	325	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

MPP8_HUMAN
NC score	0.054300 (rank : 120)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	140	Target Neighborhood Hits	948	Shared Neighborhood Hits	77
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ASB7_HUMAN
NC score	0.054285 (rank : 121)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	140	Target Neighborhood Hits	296	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
NC score	0.054247 (rank : 122)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	140	Target Neighborhood Hits	296	Shared Neighborhood Hits	68
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

PA2G6_HUMAN
NC score	0.054227 (rank : 123)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR18_HUMAN
NC score	0.053983 (rank : 124)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	140	Target Neighborhood Hits	1106	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

MIB2_HUMAN
NC score	0.053922 (rank : 125)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	140	Target Neighborhood Hits	438	Shared Neighborhood Hits	73
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NFKB2_MOUSE
NC score	0.053746 (rank : 126)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	140	Target Neighborhood Hits	326	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

PSD10_HUMAN
NC score	0.053686 (rank : 127)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	140	Target Neighborhood Hits	301	Shared Neighborhood Hits	72
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MIB2_MOUSE
NC score	0.053506 (rank : 128)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	140	Target Neighborhood Hits	409	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANKR1_HUMAN
NC score	0.053486 (rank : 129)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	140	Target Neighborhood Hits	308	Shared Neighborhood Hits	69
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

IKBE_MOUSE
NC score	0.053429 (rank : 130)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	140	Target Neighborhood Hits	308	Shared Neighborhood Hits	72
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANRA2_MOUSE
NC score	0.053271 (rank : 131)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	140	Target Neighborhood Hits	287	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB6_HUMAN
NC score	0.053176 (rank : 132)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	140	Target Neighborhood Hits	256	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR25_MOUSE
NC score	0.053147 (rank : 133)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	140	Target Neighborhood Hits	398	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR32_MOUSE
NC score	0.053103 (rank : 134)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	140	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR16_HUMAN
NC score	0.053067 (rank : 135)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	140	Target Neighborhood Hits	286	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANRA2_HUMAN
NC score	0.052912 (rank : 136)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	140	Target Neighborhood Hits	288	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

IKBA_HUMAN
NC score	0.052761 (rank : 137)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	140	Target Neighborhood Hits	280	Shared Neighborhood Hits	72
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBA_MOUSE
NC score	0.052643 (rank : 138)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	140	Target Neighborhood Hits	283	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANKR2_HUMAN
NC score	0.052575 (rank : 139)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	140	Target Neighborhood Hits	321	Shared Neighborhood Hits	69
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

EF2K_MOUSE
NC score	0.052500 (rank : 140)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	140	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

ASB6_MOUSE
NC score	0.052272 (rank : 141)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	140	Target Neighborhood Hits	264	Shared Neighborhood Hits	70
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CAC1B_MOUSE
NC score	0.051947 (rank : 142)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	140	Target Neighborhood Hits	351	Shared Neighborhood Hits	26
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

AN30A_HUMAN
NC score	0.051687 (rank : 143)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	140	Target Neighborhood Hits	1119	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKR2_MOUSE
NC score	0.051685 (rank : 144)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	140	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

SC10A_HUMAN
NC score	0.051671 (rank : 145)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	140	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

IKBB_HUMAN
NC score	0.051348 (rank : 146)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	71
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANR49_MOUSE
NC score	0.051164 (rank : 147)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	140	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

IKBB_MOUSE
NC score	0.051004 (rank : 148)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	140	Target Neighborhood Hits	284	Shared Neighborhood Hits	72
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR46_HUMAN
NC score	0.050958 (rank : 149)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	140	Target Neighborhood Hits	281	Shared Neighborhood Hits	70
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CLPB_HUMAN
NC score	0.050937 (rank : 150)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	140	Target Neighborhood Hits	265	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR22_HUMAN
NC score	0.050689 (rank : 151)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	140	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB8_HUMAN
NC score	0.050540 (rank : 152)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	140	Target Neighborhood Hits	294	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

EF2K_HUMAN
NC score	0.050527 (rank : 153)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	140	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

PSD10_MOUSE
NC score	0.050305 (rank : 154)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	140	Target Neighborhood Hits	293	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

SC10A_MOUSE
NC score	0.049368 (rank : 155)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	140	Target Neighborhood Hits	107	Shared Neighborhood Hits	31
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN4A_HUMAN
NC score	0.046856 (rank : 156)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	140	Target Neighborhood Hits	133	Shared Neighborhood Hits	29
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
NC score	0.045170 (rank : 157)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	140	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN8A_MOUSE
NC score	0.043550 (rank : 158)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	140	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CT026_HUMAN
NC score	0.043068 (rank : 159)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	140	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

CAC1E_MOUSE
NC score	0.042916 (rank : 160)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	140	Target Neighborhood Hits	167	Shared Neighborhood Hits	26
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.041955 (rank : 161)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	140	Target Neighborhood Hits	148	Shared Neighborhood Hits	22
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN8A_HUMAN
NC score	0.041901 (rank : 162)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	140	Target Neighborhood Hits	135	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

RIPK4_HUMAN
NC score	0.041723 (rank : 163)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	140	Target Neighborhood Hits	1094	Shared Neighborhood Hits	81
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_HUMAN
NC score	0.041254 (rank : 164)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	140	Target Neighborhood Hits	1075	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

UACA_HUMAN
NC score	0.038705 (rank : 165)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	140	Target Neighborhood Hits	1622	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CAC1A_MOUSE
NC score	0.036212 (rank : 166)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	140	Target Neighborhood Hits	267	Shared Neighborhood Hits	22
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

ANKK1_MOUSE
NC score	0.036062 (rank : 167)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	140	Target Neighborhood Hits	1072	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

CAC1A_HUMAN
NC score	0.034900 (rank : 168)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	140	Target Neighborhood Hits	387	Shared Neighborhood Hits	23
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

MPP10_MOUSE
NC score	0.031948 (rank : 169)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	140	Target Neighborhood Hits	251	Shared Neighborhood Hits	13
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

CAC1H_HUMAN
NC score	0.027609 (rank : 170)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	140	Target Neighborhood Hits	307	Shared Neighborhood Hits	22
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

TR143_MOUSE
NC score	0.026103 (rank : 171)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	140	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQB9, Q2NL43	Gene names	Tas2r143, T2r36, Tas2r43
Domain Architecture
Description	Taste receptor type 2 member 143 (T2R143) (Taste receptor type 2 member 43) (T2R43) (mT2R36).

ANKF1_HUMAN
NC score	0.019733 (rank : 172)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	140	Target Neighborhood Hits	126	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CTNS_MOUSE
NC score	0.019310 (rank : 173)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	140	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P57757	Gene names	Ctns
Domain Architecture
Description	Cystinosin.

CDC37_MOUSE
NC score	0.018347 (rank : 174)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	140	Target Neighborhood Hits	359	Shared Neighborhood Hits	11
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

RYR2_HUMAN
NC score	0.017735 (rank : 175)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	140	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

VPS18_MOUSE
NC score	0.017024 (rank : 176)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	140	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R307, Q8BGV6, Q8BZX6, Q8C126	Gene names	Vps18
Domain Architecture
Description	Vacuolar protein sorting-associated protein 18.

CDC37_HUMAN
NC score	0.016075 (rank : 177)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	140	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

ASB17_MOUSE
NC score	0.012271 (rank : 178)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	140	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHP9, Q9CUF9	Gene names	Asb17
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 17 (ASB-17).

DOPO_HUMAN
NC score	0.011835 (rank : 179)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	140	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P09172, Q5T381, Q96AG2	Gene names	DBH
Domain Architecture
Description	Dopamine beta-hydroxylase precursor (EC 1.14.17.1) (Dopamine beta- monooxygenase).

RBBP8_HUMAN
NC score	0.011347 (rank : 180)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	140	Target Neighborhood Hits	476	Shared Neighborhood Hits	13
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

PCDGC_HUMAN
NC score	0.009566 (rank : 181)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	O60330, O15100, Q6UW70, Q9Y5D7	Gene names	PCDHGA12, CDH21, FIB3, KIAA0588
Domain Architecture
Description	Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin 3).

PCDGB_HUMAN
NC score	0.008936 (rank : 182)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	140	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5H2, Q9Y5D8, Q9Y5D9	Gene names	PCDHGA11
Domain Architecture
Description	Protocadherin gamma A11 precursor (PCDH-gamma-A11).

SYCP1_HUMAN
NC score	0.008395 (rank : 183)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	140	Target Neighborhood Hits	1313	Shared Neighborhood Hits	29
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

PCDG7_HUMAN
NC score	0.007995 (rank : 184)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	140	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5G6, Q9Y5D0	Gene names	PCDHGA7
Domain Architecture
Description	Protocadherin gamma A7 precursor (PCDH-gamma-A7).

NET4_HUMAN
NC score	0.007054 (rank : 185)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	140	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

K0831_MOUSE
NC score	0.006916 (rank : 186)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	140	Target Neighborhood Hits	277	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

LZTS2_MOUSE
NC score	0.006802 (rank : 187)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	140	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

AKA12_HUMAN
NC score	0.005238 (rank : 188)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	140	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CP250_HUMAN
NC score	0.004000 (rank : 189)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	140	Target Neighborhood Hits	1805	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

NUMA1_HUMAN
NC score	0.003992 (rank : 190)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	140	Target Neighborhood Hits	1523	Shared Neighborhood Hits	26
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

EEA1_HUMAN
NC score	0.003836 (rank : 191)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	140	Target Neighborhood Hits	1796	Shared Neighborhood Hits	36
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RIMS1_HUMAN
NC score	0.003713 (rank : 192)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	140	Target Neighborhood Hits	437	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYNE1_HUMAN
NC score	0.003557 (rank : 193)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	140	Target Neighborhood Hits	1484	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TIF1G_MOUSE
NC score	0.002161 (rank : 194)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	140	Target Neighborhood Hits	498	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PRDM2_HUMAN
NC score	0.001012 (rank : 195)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	8
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SLK_HUMAN
NC score	-0.003605 (rank : 196)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	140	Target Neighborhood Hits	1775	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).