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Network neighborhood for query Sequence : TRPC1_MOUSE

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TRPC1_MOUSE
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999633 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC4_MOUSE
θ value	8.82788e-181 (rank : 3)	NC score	0.959333 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	141	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
θ value	1.96665e-180 (rank : 4)	NC score	0.959458 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC5_MOUSE
θ value	4.1007e-178 (rank : 5)	NC score	0.962736 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	124	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
θ value	1.55827e-177 (rank : 6)	NC score	0.962613 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	122	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC3_HUMAN
θ value	3.19119e-122 (rank : 7)	NC score	0.942231 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	4.60808e-121 (rank : 8)	NC score	0.941564 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_HUMAN
θ value	1.81207e-117 (rank : 9)	NC score	0.938186 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	171	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	1.69605e-115 (rank : 10)	NC score	0.941168 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	171	Shared Neighborhood Hits	57
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	5.10665e-112 (rank : 11)	NC score	0.942055 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	123	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	1.25781e-110 (rank : 12)	NC score	0.942141 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC2_MOUSE
θ value	3.0147e-88 (rank : 13)	NC score	0.941288 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPM8_MOUSE
θ value	2.13673e-09 (rank : 14)	NC score	0.475596 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
θ value	2.79066e-09 (rank : 15)	NC score	0.472152 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_HUMAN
θ value	6.21693e-09 (rank : 16)	NC score	0.394487 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
θ value	1.69304e-06 (rank : 17)	NC score	0.364505 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPV1_MOUSE
θ value	3.77169e-06 (rank : 18)	NC score	0.234871 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	189	Shared Neighborhood Hits	64
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
θ value	9.29e-05 (rank : 19)	NC score	0.230705 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPM6_MOUSE
θ value	0.000461057 (rank : 20)	NC score	0.346213 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

SC11A_HUMAN
θ value	0.000786445 (rank : 21)	NC score	0.076649 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	111	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

TRPV3_HUMAN
θ value	0.000786445 (rank : 22)	NC score	0.269882 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	198	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPM7_HUMAN
θ value	0.00134147 (rank : 23)	NC score	0.354114 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM7_MOUSE
θ value	0.00134147 (rank : 24)	NC score	0.354211 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

RAB7L_MOUSE
θ value	0.00869519 (rank : 25)	NC score	0.020180 (rank : 106)
Query Neighborhood Hits	87	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YQ1	Gene names	Rab7l1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-7L1 (Rab-7-like protein 1).

SCN1A_HUMAN
θ value	0.0148317 (rank : 26)	NC score	0.070580 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	148	Shared Neighborhood Hits	18
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

ACBD6_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.100613 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

SCN3A_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.068914 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN5A_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.070735 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	145	Shared Neighborhood Hits	22
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

RAB7L_HUMAN
θ value	0.0736092 (rank : 30)	NC score	0.016963 (rank : 109)
Query Neighborhood Hits	87	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	O14966	Gene names	RAB7L1
Domain Architecture
Description	Ras-related protein Rab-7L1 (Rab-7-like protein 1).

EHMT1_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.070890 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SCN4A_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.074245 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	133	Shared Neighborhood Hits	23
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN9A_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.067327 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN2A_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.066677 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN8A_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.072179 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

TRPV4_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.184575 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	150	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ACBD6_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.075110 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	304	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

TRPV3_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.244170 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	188	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

ANR50_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.057022 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	361	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

RAI14_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.045603 (rank : 90)
Query Neighborhood Hits	87	Target Neighborhood Hits	1367	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

TRPV2_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.132224 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	111	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

BCOR_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.067054 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	49
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.068335 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	521	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SCN8A_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.069190 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

TRPV4_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.167087 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV6_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.163563 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

AN36B_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.069239 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	294	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ASB2_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.043494 (rank : 93)
Query Neighborhood Hits	87	Target Neighborhood Hits	309	Shared Neighborhood Hits	46
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.065151 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	316	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CSKI2_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.054193 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	812	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MIB1_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.044802 (rank : 91)
Query Neighborhood Hits	87	Target Neighborhood Hits	470	Shared Neighborhood Hits	52
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.044610 (rank : 92)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MYPT2_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.046375 (rank : 89)
Query Neighborhood Hits	87	Target Neighborhood Hits	707	Shared Neighborhood Hits	46
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

SC11A_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.067494 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

TRPM3_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.268812 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

AN30A_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.032291 (rank : 101)
Query Neighborhood Hits	87	Target Neighborhood Hits	1119	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANK1_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.082709 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	416	Shared Neighborhood Hits	56
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.082677 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	430	Shared Neighborhood Hits	56
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK3_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.060429 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	853	Shared Neighborhood Hits	58
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

S61A1_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.024790 (rank : 103)
Query Neighborhood Hits	87	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P61619, P38378, P57726, Q5JPF8, Q8N0Z4, Q8N3U3, Q8NC71, Q9BU16, Q9Y2R3	Gene names	SEC61A1, SEC61A
Domain Architecture
Description	Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha- 1).

S61A1_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.024790 (rank : 104)
Query Neighborhood Hits	87	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P61620, P38378, P57726, Q3TXA5	Gene names	Sec61a1, Sec61a
Domain Architecture
Description	Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha- 1).

SC10A_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.077196 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	116	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

TNI3K_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.018772 (rank : 107)
Query Neighborhood Hits	87	Target Neighborhood Hits	1084	Shared Neighborhood Hits	48
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

BZFB_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.033130 (rank : 100)
Query Neighborhood Hits	87	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWU6, Q3TET9, Q9CRP2, Q9JK78	Gene names	Bfzb
Domain Architecture
Description	Basic FGF-repressed Zic-binding protein (mbFZb).

TNI3K_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.017600 (rank : 108)
Query Neighborhood Hits	87	Target Neighborhood Hits	1079	Shared Neighborhood Hits	48
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TRPV6_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.169589 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	262	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ANK2_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.047317 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	1615	Shared Neighborhood Hits	55
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR21_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.048017 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	864	Shared Neighborhood Hits	52
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CSKI2_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.055288 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	747	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TRPM6_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.316798 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPV5_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.175384 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	278	Shared Neighborhood Hits	65
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

BZFB_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.028900 (rank : 102)
Query Neighborhood Hits	87	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVA1, Q5T348, Q5T351, Q5T353, Q86YU3, Q86YU4, Q96H66, Q9H438, Q9H452, Q9H9K8, Q9H9R5	Gene names	BZFB, C20orf44
Domain Architecture
Description	Basic FGF-repressed Zic-binding protein (bFZb).

CROCC_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.005840 (rank : 112)
Query Neighborhood Hits	87	Target Neighborhood Hits	1409	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

INVS_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.038420 (rank : 95)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	46
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

NOTC1_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.012710 (rank : 110)
Query Neighborhood Hits	87	Target Neighborhood Hits	916	Shared Neighborhood Hits	44
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RN5A_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.062355 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	899	Shared Neighborhood Hits	56
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR26_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.042282 (rank : 94)
Query Neighborhood Hits	87	Target Neighborhood Hits	1614	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RAI14_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.022953 (rank : 105)
Query Neighborhood Hits	87	Target Neighborhood Hits	1505	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TRPV5_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.142477 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	261	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR44_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.050361 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	318	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR46_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.036558 (rank : 97)
Query Neighborhood Hits	87	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR46_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.034082 (rank : 99)
Query Neighborhood Hits	87	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CN145_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.001592 (rank : 114)
Query Neighborhood Hits	87	Target Neighborhood Hits	1196	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

K1H8_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.002078 (rank : 113)
Query Neighborhood Hits	87	Target Neighborhood Hits	394	Shared Neighborhood Hits	7
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

ASB2_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.038257 (rank : 96)
Query Neighborhood Hits	87	Target Neighborhood Hits	321	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CLUA1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.009557 (rank : 111)
Query Neighborhood Hits	87	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

MPP8_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.035927 (rank : 98)
Query Neighborhood Hits	87	Target Neighborhood Hits	948	Shared Neighborhood Hits	44
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

AN13A_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.054408 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	243	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANKS1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.066573 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	438	Shared Neighborhood Hits	53
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.061721 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	453	Shared Neighborhood Hits	48
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS6_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.051361 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	411	Shared Neighborhood Hits	51
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKY2_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.062262 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	306	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANKY2_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.084401 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	316	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR52_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.058157 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	322	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.058071 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.051423 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	292	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB3_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.056519 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	316	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

BARD1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.060425 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	411	Shared Neighborhood Hits	46
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CTTB2_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.062695 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	1061	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

EHMT2_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.053080 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	498	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GABP2_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.050227 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	429	Shared Neighborhood Hits	47
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

PK2L1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.159548 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.100942 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	90	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.135314 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.121668 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.122077 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	99	Shared Neighborhood Hits	27
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

POTE8_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.052846 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

RN5A_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.064344 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	608	Shared Neighborhood Hits	49
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SC10A_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.071830 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN7A_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.057228 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	135	Shared Neighborhood Hits	17
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

TNKS1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.052894 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	477	Shared Neighborhood Hits	54
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TRPA1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.066532 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TRPA1_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.058558 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.128185 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	130	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

Hits sorted by NC score

TRPC1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.999633 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC5_MOUSE
NC score	0.962736 (rank : 3)	θ value	4.1007e-178 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	124	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.962613 (rank : 4)	θ value	1.55827e-177 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	122	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC4_HUMAN
NC score	0.959458 (rank : 5)	θ value	1.96665e-180 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.959333 (rank : 6)	θ value	8.82788e-181 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	141	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC3_HUMAN
NC score	0.942231 (rank : 7)	θ value	3.19119e-122 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC7_MOUSE
NC score	0.942141 (rank : 8)	θ value	1.25781e-110 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.942055 (rank : 9)	θ value	5.10665e-112 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	123	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC3_MOUSE
NC score	0.941564 (rank : 10)	θ value	4.60808e-121 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC2_MOUSE
NC score	0.941288 (rank : 11)	θ value	3.0147e-88 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC6_MOUSE
NC score	0.941168 (rank : 12)	θ value	1.69605e-115 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	171	Shared Neighborhood Hits	57
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC6_HUMAN
NC score	0.938186 (rank : 13)	θ value	1.81207e-117 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	171	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPM8_MOUSE
NC score	0.475596 (rank : 14)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
NC score	0.472152 (rank : 15)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_HUMAN
NC score	0.394487 (rank : 16)	θ value	6.21693e-09 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
NC score	0.364505 (rank : 17)	θ value	1.69304e-06 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM7_MOUSE
NC score	0.354211 (rank : 18)	θ value	0.00134147 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
NC score	0.354114 (rank : 19)	θ value	0.00134147 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_MOUSE
NC score	0.346213 (rank : 20)	θ value	0.000461057 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_HUMAN
NC score	0.316798 (rank : 21)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPV3_HUMAN
NC score	0.269882 (rank : 22)	θ value	0.000786445 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	198	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPM3_HUMAN
NC score	0.268812 (rank : 23)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV3_MOUSE
NC score	0.244170 (rank : 24)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	188	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_MOUSE
NC score	0.234871 (rank : 25)	θ value	3.77169e-06 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	189	Shared Neighborhood Hits	64
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
NC score	0.230705 (rank : 26)	θ value	9.29e-05 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV4_HUMAN
NC score	0.184575 (rank : 27)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	150	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_MOUSE
NC score	0.175384 (rank : 28)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	278	Shared Neighborhood Hits	65
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
NC score	0.169589 (rank : 29)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	262	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV4_MOUSE
NC score	0.167087 (rank : 30)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV6_MOUSE
NC score	0.163563 (rank : 31)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

PK2L1_HUMAN
NC score	0.159548 (rank : 32)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	87	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPV5_HUMAN
NC score	0.142477 (rank : 33)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	261	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

PK2L2_MOUSE
NC score	0.135314 (rank : 34)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	87	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV2_MOUSE
NC score	0.132224 (rank : 35)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	111	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV2_HUMAN
NC score	0.128185 (rank : 36)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	87	Target Neighborhood Hits	130	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PKD2_MOUSE
NC score	0.122077 (rank : 37)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	87	Target Neighborhood Hits	99	Shared Neighborhood Hits	27
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.121668 (rank : 38)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	87	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PK2L2_HUMAN
NC score	0.100942 (rank : 39)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	87	Target Neighborhood Hits	90	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

ACBD6_MOUSE
NC score	0.100613 (rank : 40)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKY2_MOUSE
NC score	0.084401 (rank : 41)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	87	Target Neighborhood Hits	316	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANK1_HUMAN
NC score	0.082709 (rank : 42)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	416	Shared Neighborhood Hits	56
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.082677 (rank : 43)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	430	Shared Neighborhood Hits	56
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

SC10A_HUMAN
NC score	0.077196 (rank : 44)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	116	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC11A_HUMAN
NC score	0.076649 (rank : 45)	θ value	0.000786445 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	111	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

ACBD6_HUMAN
NC score	0.075110 (rank : 46)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	304	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

SCN4A_HUMAN
NC score	0.074245 (rank : 47)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	133	Shared Neighborhood Hits	23
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN8A_MOUSE
NC score	0.072179 (rank : 48)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_MOUSE
NC score	0.071830 (rank : 49)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	87	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

EHMT1_HUMAN
NC score	0.070890 (rank : 50)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SCN5A_HUMAN
NC score	0.070735 (rank : 51)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	145	Shared Neighborhood Hits	22
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN1A_HUMAN
NC score	0.070580 (rank : 52)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	148	Shared Neighborhood Hits	18
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

AN36B_HUMAN
NC score	0.069239 (rank : 53)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	294	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

SCN8A_HUMAN
NC score	0.069190 (rank : 54)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN3A_HUMAN
NC score	0.068914 (rank : 55)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

BCOR_MOUSE
NC score	0.068335 (rank : 56)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	521	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SC11A_MOUSE
NC score	0.067494 (rank : 57)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN9A_HUMAN
NC score	0.067327 (rank : 58)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

BCOR_HUMAN
NC score	0.067054 (rank : 59)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	49
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SCN2A_HUMAN
NC score	0.066677 (rank : 60)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

ANKS1_HUMAN
NC score	0.066573 (rank : 61)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	87	Target Neighborhood Hits	438	Shared Neighborhood Hits	53
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

TRPA1_HUMAN
NC score	0.066532 (rank : 62)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	87	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ASB3_HUMAN
NC score	0.065151 (rank : 63)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	316	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

RN5A_HUMAN
NC score	0.064344 (rank : 64)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	87	Target Neighborhood Hits	608	Shared Neighborhood Hits	49
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CTTB2_HUMAN
NC score	0.062695 (rank : 65)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	87	Target Neighborhood Hits	1061	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

RN5A_MOUSE
NC score	0.062355 (rank : 66)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	899	Shared Neighborhood Hits	56
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKY2_HUMAN
NC score	0.062262 (rank : 67)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	87	Target Neighborhood Hits	306	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANKS1_MOUSE
NC score	0.061721 (rank : 68)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	87	Target Neighborhood Hits	453	Shared Neighborhood Hits	48
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANK3_HUMAN
NC score	0.060429 (rank : 69)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	853	Shared Neighborhood Hits	58
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

BARD1_MOUSE
NC score	0.060425 (rank : 70)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	87	Target Neighborhood Hits	411	Shared Neighborhood Hits	46
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

TRPA1_MOUSE
NC score	0.058558 (rank : 71)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	87	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANR52_HUMAN
NC score	0.058157 (rank : 72)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	87	Target Neighborhood Hits	322	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
NC score	0.058071 (rank : 73)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	87	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

SCN7A_HUMAN
NC score	0.057228 (rank : 74)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	87	Target Neighborhood Hits	135	Shared Neighborhood Hits	17
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

ANR50_HUMAN
NC score	0.057022 (rank : 75)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	361	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ASB3_MOUSE
NC score	0.056519 (rank : 76)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	87	Target Neighborhood Hits	316	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CSKI2_HUMAN
NC score	0.055288 (rank : 77)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	747	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

AN13A_HUMAN
NC score	0.054408 (rank : 78)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	243	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

CSKI2_MOUSE
NC score	0.054193 (rank : 79)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	812	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

EHMT2_HUMAN
NC score	0.053080 (rank : 80)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	87	Target Neighborhood Hits	498	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TNKS1_HUMAN
NC score	0.052894 (rank : 81)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	87	Target Neighborhood Hits	477	Shared Neighborhood Hits	54
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

POTE8_HUMAN
NC score	0.052846 (rank : 82)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	87	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ASB1_MOUSE
NC score	0.051423 (rank : 83)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	87	Target Neighborhood Hits	292	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANKS6_HUMAN
NC score	0.051361 (rank : 84)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	87	Target Neighborhood Hits	411	Shared Neighborhood Hits	51
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR44_HUMAN
NC score	0.050361 (rank : 85)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	318	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

GABP2_MOUSE
NC score	0.050227 (rank : 86)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	87	Target Neighborhood Hits	429	Shared Neighborhood Hits	47
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR21_HUMAN
NC score	0.048017 (rank : 87)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	864	Shared Neighborhood Hits	52
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANK2_HUMAN
NC score	0.047317 (rank : 88)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	1615	Shared Neighborhood Hits	55
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MYPT2_HUMAN
NC score	0.046375 (rank : 89)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	707	Shared Neighborhood Hits	46
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

RAI14_HUMAN
NC score	0.045603 (rank : 90)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	1367	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

MIB1_HUMAN
NC score	0.044802 (rank : 91)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	470	Shared Neighborhood Hits	52
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.044610 (rank : 92)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ASB2_HUMAN
NC score	0.043494 (rank : 93)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	309	Shared Neighborhood Hits	46
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR26_HUMAN
NC score	0.042282 (rank : 94)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	1614	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

INVS_MOUSE
NC score	0.038420 (rank : 95)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	46
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB2_MOUSE
NC score	0.038257 (rank : 96)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	321	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR46_HUMAN
NC score	0.036558 (rank : 97)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

MPP8_HUMAN
NC score	0.035927 (rank : 98)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	948	Shared Neighborhood Hits	44
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR46_MOUSE
NC score	0.034082 (rank : 99)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

BZFB_MOUSE
NC score	0.033130 (rank : 100)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWU6, Q3TET9, Q9CRP2, Q9JK78	Gene names	Bfzb
Domain Architecture
Description	Basic FGF-repressed Zic-binding protein (mbFZb).

AN30A_HUMAN
NC score	0.032291 (rank : 101)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	1119	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

BZFB_HUMAN
NC score	0.028900 (rank : 102)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVA1, Q5T348, Q5T351, Q5T353, Q86YU3, Q86YU4, Q96H66, Q9H438, Q9H452, Q9H9K8, Q9H9R5	Gene names	BZFB, C20orf44
Domain Architecture
Description	Basic FGF-repressed Zic-binding protein (bFZb).

S61A1_HUMAN
NC score	0.024790 (rank : 103)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P61619, P38378, P57726, Q5JPF8, Q8N0Z4, Q8N3U3, Q8NC71, Q9BU16, Q9Y2R3	Gene names	SEC61A1, SEC61A
Domain Architecture
Description	Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha- 1).

S61A1_MOUSE
NC score	0.024790 (rank : 104)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P61620, P38378, P57726, Q3TXA5	Gene names	Sec61a1, Sec61a
Domain Architecture
Description	Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha- 1).

RAI14_MOUSE
NC score	0.022953 (rank : 105)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	1505	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RAB7L_MOUSE
NC score	0.020180 (rank : 106)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YQ1	Gene names	Rab7l1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-7L1 (Rab-7-like protein 1).

TNI3K_HUMAN
NC score	0.018772 (rank : 107)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	1084	Shared Neighborhood Hits	48
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.017600 (rank : 108)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	1079	Shared Neighborhood Hits	48
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

RAB7L_HUMAN
NC score	0.016963 (rank : 109)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	O14966	Gene names	RAB7L1
Domain Architecture
Description	Ras-related protein Rab-7L1 (Rab-7-like protein 1).

NOTC1_MOUSE
NC score	0.012710 (rank : 110)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	916	Shared Neighborhood Hits	44
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CLUA1_MOUSE
NC score	0.009557 (rank : 111)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CROCC_HUMAN
NC score	0.005840 (rank : 112)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	1409	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

K1H8_HUMAN
NC score	0.002078 (rank : 113)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	394	Shared Neighborhood Hits	7
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

CN145_HUMAN
NC score	0.001592 (rank : 114)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	1196	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.