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Network neighborhood for query Sequence : EHMT1_HUMAN

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EHMT1_HUMAN
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EHMT1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	417	Target Neighborhood Hits	417	Shared Neighborhood Hits	417
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_HUMAN
θ value	0 (rank : 2)	NC score	0.981392 (rank : 2)
Query Neighborhood Hits	417	Target Neighborhood Hits	498	Shared Neighborhood Hits	330
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	0 (rank : 3)	NC score	0.965465 (rank : 3)
Query Neighborhood Hits	417	Target Neighborhood Hits	750	Shared Neighborhood Hits	339
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

SUV91_MOUSE
θ value	3.73686e-38 (rank : 4)	NC score	0.410262 (rank : 258)
Query Neighborhood Hits	417	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV91_HUMAN
θ value	1.08726e-37 (rank : 5)	NC score	0.413455 (rank : 252)
Query Neighborhood Hits	417	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV92_HUMAN
θ value	3.4976e-36 (rank : 6)	NC score	0.408810 (rank : 259)
Query Neighborhood Hits	417	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
θ value	7.79185e-36 (rank : 7)	NC score	0.406699 (rank : 261)
Query Neighborhood Hits	417	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

ANR50_HUMAN
θ value	1.6813e-30 (rank : 8)	NC score	0.871456 (rank : 8)
Query Neighborhood Hits	417	Target Neighborhood Hits	361	Shared Neighborhood Hits	302
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANKR6_HUMAN
θ value	3.74554e-30 (rank : 9)	NC score	0.875772 (rank : 7)
Query Neighborhood Hits	417	Target Neighborhood Hits	439	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANK1_HUMAN
θ value	2.68423e-28 (rank : 10)	NC score	0.850371 (rank : 30)
Query Neighborhood Hits	417	Target Neighborhood Hits	416	Shared Neighborhood Hits	308
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	2.68423e-28 (rank : 11)	NC score	0.849371 (rank : 34)
Query Neighborhood Hits	417	Target Neighborhood Hits	430	Shared Neighborhood Hits	309
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK3_HUMAN
θ value	2.68423e-28 (rank : 12)	NC score	0.841433 (rank : 44)
Query Neighborhood Hits	417	Target Neighborhood Hits	853	Shared Neighborhood Hits	329
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TNKS1_HUMAN
θ value	3.87602e-27 (rank : 13)	NC score	0.853597 (rank : 25)
Query Neighborhood Hits	417	Target Neighborhood Hits	477	Shared Neighborhood Hits	307
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR28_MOUSE
θ value	1.47289e-26 (rank : 14)	NC score	0.859351 (rank : 17)
Query Neighborhood Hits	417	Target Neighborhood Hits	314	Shared Neighborhood Hits	298
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
θ value	2.51237e-26 (rank : 15)	NC score	0.857930 (rank : 20)
Query Neighborhood Hits	417	Target Neighborhood Hits	314	Shared Neighborhood Hits	298
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

TNKS2_HUMAN
θ value	9.54697e-26 (rank : 16)	NC score	0.853245 (rank : 26)
Query Neighborhood Hits	417	Target Neighborhood Hits	361	Shared Neighborhood Hits	301
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANK2_HUMAN
θ value	1.24688e-25 (rank : 17)	NC score	0.792863 (rank : 112)
Query Neighborhood Hits	417	Target Neighborhood Hits	1615	Shared Neighborhood Hits	353
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKK1_HUMAN
θ value	2.77775e-25 (rank : 18)	NC score	0.553480 (rank : 208)
Query Neighborhood Hits	417	Target Neighborhood Hits	1075	Shared Neighborhood Hits	299
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR44_HUMAN
θ value	2.77775e-25 (rank : 19)	NC score	0.861538 (rank : 12)
Query Neighborhood Hits	417	Target Neighborhood Hits	318	Shared Neighborhood Hits	303
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ZDH17_HUMAN
θ value	1.37858e-24 (rank : 20)	NC score	0.769743 (rank : 130)
Query Neighborhood Hits	417	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

DAPK1_MOUSE
θ value	4.01107e-24 (rank : 21)	NC score	0.393820 (rank : 262)
Query Neighborhood Hits	417	Target Neighborhood Hits	1138	Shared Neighborhood Hits	299
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ZDH17_MOUSE
θ value	4.01107e-24 (rank : 22)	NC score	0.765377 (rank : 131)
Query Neighborhood Hits	417	Target Neighborhood Hits	328	Shared Neighborhood Hits	277
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANKK1_MOUSE
θ value	6.84181e-24 (rank : 23)	NC score	0.537452 (rank : 219)
Query Neighborhood Hits	417	Target Neighborhood Hits	1072	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANKR2_MOUSE
θ value	1.16704e-23 (rank : 24)	NC score	0.865720 (rank : 10)
Query Neighborhood Hits	417	Target Neighborhood Hits	312	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

SETB1_HUMAN
θ value	1.16704e-23 (rank : 25)	NC score	0.348462 (rank : 275)
Query Neighborhood Hits	417	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_MOUSE
θ value	1.16704e-23 (rank : 26)	NC score	0.352339 (rank : 272)
Query Neighborhood Hits	417	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

INVS_HUMAN
θ value	1.5242e-23 (rank : 27)	NC score	0.859057 (rank : 18)
Query Neighborhood Hits	417	Target Neighborhood Hits	455	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	3.39556e-23 (rank : 28)	NC score	0.852276 (rank : 28)
Query Neighborhood Hits	417	Target Neighborhood Hits	609	Shared Neighborhood Hits	308
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR52_MOUSE
θ value	5.79196e-23 (rank : 29)	NC score	0.849643 (rank : 32)
Query Neighborhood Hits	417	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
θ value	7.56453e-23 (rank : 30)	NC score	0.849440 (rank : 33)
Query Neighborhood Hits	417	Target Neighborhood Hits	322	Shared Neighborhood Hits	302
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

RIPK4_HUMAN
θ value	7.56453e-23 (rank : 31)	NC score	0.544650 (rank : 213)
Query Neighborhood Hits	417	Target Neighborhood Hits	1094	Shared Neighborhood Hits	303
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

DAPK1_HUMAN
θ value	9.87957e-23 (rank : 32)	NC score	0.384952 (rank : 263)
Query Neighborhood Hits	417	Target Neighborhood Hits	1130	Shared Neighborhood Hits	294
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TNI3K_HUMAN
θ value	9.87957e-23 (rank : 33)	NC score	0.434821 (rank : 249)
Query Neighborhood Hits	417	Target Neighborhood Hits	1084	Shared Neighborhood Hits	300
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

PSD10_HUMAN
θ value	2.87452e-22 (rank : 34)	NC score	0.880454 (rank : 5)
Query Neighborhood Hits	417	Target Neighborhood Hits	301	Shared Neighborhood Hits	292
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR2_HUMAN
θ value	8.36355e-22 (rank : 35)	NC score	0.862422 (rank : 11)
Query Neighborhood Hits	417	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR29_HUMAN
θ value	8.36355e-22 (rank : 36)	NC score	0.881440 (rank : 4)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	290
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR42_MOUSE
θ value	4.15078e-21 (rank : 37)	NC score	0.855908 (rank : 23)
Query Neighborhood Hits	417	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

PSD10_MOUSE
θ value	4.15078e-21 (rank : 38)	NC score	0.878837 (rank : 6)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

SETD2_HUMAN
θ value	7.0802e-21 (rank : 39)	NC score	0.339155 (rank : 278)
Query Neighborhood Hits	417	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ASB2_HUMAN
θ value	2.06002e-20 (rank : 40)	NC score	0.851835 (rank : 29)
Query Neighborhood Hits	417	Target Neighborhood Hits	309	Shared Neighborhood Hits	292
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKR1_HUMAN
θ value	7.82807e-20 (rank : 41)	NC score	0.856870 (rank : 22)
Query Neighborhood Hits	417	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

RAI14_MOUSE
θ value	2.97466e-19 (rank : 42)	NC score	0.601898 (rank : 196)
Query Neighborhood Hits	417	Target Neighborhood Hits	1505	Shared Neighborhood Hits	315
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANKR1_MOUSE
θ value	3.88503e-19 (rank : 43)	NC score	0.855320 (rank : 24)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	288
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

MIB2_MOUSE
θ value	3.88503e-19 (rank : 44)	NC score	0.811412 (rank : 85)
Query Neighborhood Hits	417	Target Neighborhood Hits	409	Shared Neighborhood Hits	283
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

TRPA1_MOUSE
θ value	3.88503e-19 (rank : 45)	NC score	0.834584 (rank : 51)
Query Neighborhood Hits	417	Target Neighborhood Hits	343	Shared Neighborhood Hits	294
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

RAI14_HUMAN
θ value	5.07402e-19 (rank : 46)	NC score	0.634124 (rank : 191)
Query Neighborhood Hits	417	Target Neighborhood Hits	1367	Shared Neighborhood Hits	312
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ASB3_HUMAN
θ value	6.62687e-19 (rank : 47)	NC score	0.860047 (rank : 15)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB10_HUMAN
θ value	1.47631e-18 (rank : 48)	NC score	0.853004 (rank : 27)
Query Neighborhood Hits	417	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CSKI1_MOUSE
θ value	1.47631e-18 (rank : 49)	NC score	0.789598 (rank : 117)
Query Neighborhood Hits	417	Target Neighborhood Hits	1031	Shared Neighborhood Hits	312
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MIB2_HUMAN
θ value	1.92812e-18 (rank : 50)	NC score	0.811424 (rank : 84)
Query Neighborhood Hits	417	Target Neighborhood Hits	438	Shared Neighborhood Hits	288
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

SETB2_HUMAN
θ value	1.92812e-18 (rank : 51)	NC score	0.359776 (rank : 270)
Query Neighborhood Hits	417	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

ANKS1_HUMAN
θ value	2.5182e-18 (rank : 52)	NC score	0.818057 (rank : 71)
Query Neighborhood Hits	417	Target Neighborhood Hits	438	Shared Neighborhood Hits	304
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB2_MOUSE
θ value	2.5182e-18 (rank : 53)	NC score	0.845458 (rank : 38)
Query Neighborhood Hits	417	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB10_MOUSE
θ value	3.28887e-18 (rank : 54)	NC score	0.849276 (rank : 35)
Query Neighborhood Hits	417	Target Neighborhood Hits	301	Shared Neighborhood Hits	286
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

FANK1_HUMAN
θ value	4.29542e-18 (rank : 55)	NC score	0.860499 (rank : 13)
Query Neighborhood Hits	417	Target Neighborhood Hits	326	Shared Neighborhood Hits	288
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

TNI3K_MOUSE
θ value	4.29542e-18 (rank : 56)	NC score	0.427459 (rank : 250)
Query Neighborhood Hits	417	Target Neighborhood Hits	1079	Shared Neighborhood Hits	298
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ASB3_MOUSE
θ value	5.60996e-18 (rank : 57)	NC score	0.858347 (rank : 19)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CSKI1_HUMAN
θ value	5.60996e-18 (rank : 58)	NC score	0.790193 (rank : 116)
Query Neighborhood Hits	417	Target Neighborhood Hits	997	Shared Neighborhood Hits	315
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR16_HUMAN
θ value	1.24977e-17 (rank : 59)	NC score	0.867114 (rank : 9)
Query Neighborhood Hits	417	Target Neighborhood Hits	286	Shared Neighborhood Hits	282
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

EZH1_MOUSE
θ value	1.24977e-17 (rank : 60)	NC score	0.333651 (rank : 283)
Query Neighborhood Hits	417	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FANK1_MOUSE
θ value	2.13179e-17 (rank : 61)	NC score	0.859352 (rank : 16)
Query Neighborhood Hits	417	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

EZH1_HUMAN
θ value	2.7842e-17 (rank : 62)	NC score	0.334046 (rank : 281)
Query Neighborhood Hits	417	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

CTTB2_HUMAN
θ value	3.63628e-17 (rank : 63)	NC score	0.734526 (rank : 150)
Query Neighborhood Hits	417	Target Neighborhood Hits	1061	Shared Neighborhood Hits	301
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR35_HUMAN
θ value	4.74913e-17 (rank : 64)	NC score	0.785371 (rank : 123)
Query Neighborhood Hits	417	Target Neighborhood Hits	784	Shared Neighborhood Hits	295
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB15_HUMAN
θ value	4.74913e-17 (rank : 65)	NC score	0.823413 (rank : 63)
Query Neighborhood Hits	417	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKR5_HUMAN
θ value	6.20254e-17 (rank : 66)	NC score	0.828965 (rank : 57)
Query Neighborhood Hits	417	Target Neighborhood Hits	297	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

TRPA1_HUMAN
θ value	6.20254e-17 (rank : 67)	NC score	0.832196 (rank : 53)
Query Neighborhood Hits	417	Target Neighborhood Hits	339	Shared Neighborhood Hits	297
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

UACA_HUMAN
θ value	6.20254e-17 (rank : 68)	NC score	0.501416 (rank : 230)
Query Neighborhood Hits	417	Target Neighborhood Hits	1622	Shared Neighborhood Hits	302
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MIB1_HUMAN
θ value	1.80466e-16 (rank : 69)	NC score	0.814354 (rank : 76)
Query Neighborhood Hits	417	Target Neighborhood Hits	470	Shared Neighborhood Hits	298
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

NOTC4_MOUSE
θ value	1.80466e-16 (rank : 70)	NC score	0.459016 (rank : 241)
Query Neighborhood Hits	417	Target Neighborhood Hits	872	Shared Neighborhood Hits	288
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NSD1_HUMAN
θ value	1.80466e-16 (rank : 71)	NC score	0.278940 (rank : 298)
Query Neighborhood Hits	417	Target Neighborhood Hits	427	Shared Neighborhood Hits	48
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

RN5A_MOUSE
θ value	1.80466e-16 (rank : 72)	NC score	0.752047 (rank : 139)
Query Neighborhood Hits	417	Target Neighborhood Hits	899	Shared Neighborhood Hits	299
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CSKI2_HUMAN
θ value	2.35696e-16 (rank : 73)	NC score	0.797949 (rank : 103)
Query Neighborhood Hits	417	Target Neighborhood Hits	747	Shared Neighborhood Hits	312
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ZDH13_HUMAN
θ value	2.35696e-16 (rank : 74)	NC score	0.755554 (rank : 135)
Query Neighborhood Hits	417	Target Neighborhood Hits	322	Shared Neighborhood Hits	276
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ZDH13_MOUSE
θ value	2.35696e-16 (rank : 75)	NC score	0.752975 (rank : 138)
Query Neighborhood Hits	417	Target Neighborhood Hits	329	Shared Neighborhood Hits	279
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

CSKI2_MOUSE
θ value	3.07829e-16 (rank : 76)	NC score	0.795875 (rank : 105)
Query Neighborhood Hits	417	Target Neighborhood Hits	812	Shared Neighborhood Hits	308
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MIB1_MOUSE
θ value	3.07829e-16 (rank : 77)	NC score	0.813394 (rank : 79)
Query Neighborhood Hits	417	Target Neighborhood Hits	471	Shared Neighborhood Hits	296
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

AN36B_HUMAN
θ value	4.02038e-16 (rank : 78)	NC score	0.813943 (rank : 77)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	288
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

NSD1_MOUSE
θ value	4.02038e-16 (rank : 79)	NC score	0.282136 (rank : 295)
Query Neighborhood Hits	417	Target Neighborhood Hits	472	Shared Neighborhood Hits	45
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

UACA_MOUSE
θ value	4.02038e-16 (rank : 80)	NC score	0.475399 (rank : 238)
Query Neighborhood Hits	417	Target Neighborhood Hits	1620	Shared Neighborhood Hits	297
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ASB15_MOUSE
θ value	5.25075e-16 (rank : 81)	NC score	0.812683 (rank : 81)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

NOTC4_HUMAN
θ value	6.85773e-16 (rank : 82)	NC score	0.453652 (rank : 246)
Query Neighborhood Hits	417	Target Neighborhood Hits	905	Shared Neighborhood Hits	290
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

PA2G6_MOUSE
θ value	8.95645e-16 (rank : 83)	NC score	0.824263 (rank : 62)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RFXK_HUMAN
θ value	1.16975e-15 (rank : 84)	NC score	0.826255 (rank : 60)
Query Neighborhood Hits	417	Target Neighborhood Hits	282	Shared Neighborhood Hits	265
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANKS1_MOUSE
θ value	1.52774e-15 (rank : 85)	NC score	0.802968 (rank : 99)
Query Neighborhood Hits	417	Target Neighborhood Hits	453	Shared Neighborhood Hits	299
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR23_MOUSE
θ value	1.52774e-15 (rank : 86)	NC score	0.860259 (rank : 14)
Query Neighborhood Hits	417	Target Neighborhood Hits	296	Shared Neighborhood Hits	288
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

EZH2_HUMAN
θ value	2.60593e-15 (rank : 87)	NC score	0.333982 (rank : 282)
Query Neighborhood Hits	417	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

ANR42_HUMAN
θ value	3.40345e-15 (rank : 88)	NC score	0.846014 (rank : 37)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB13_HUMAN
θ value	3.40345e-15 (rank : 89)	NC score	0.843069 (rank : 42)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	3.40345e-15 (rank : 90)	NC score	0.843249 (rank : 41)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

PP16A_HUMAN
θ value	3.40345e-15 (rank : 91)	NC score	0.809087 (rank : 92)
Query Neighborhood Hits	417	Target Neighborhood Hits	340	Shared Neighborhood Hits	276
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ASB14_MOUSE
θ value	5.8054e-15 (rank : 92)	NC score	0.812622 (rank : 83)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANKR5_MOUSE
θ value	7.58209e-15 (rank : 93)	NC score	0.829117 (rank : 56)
Query Neighborhood Hits	417	Target Neighborhood Hits	298	Shared Neighborhood Hits	285
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR23_HUMAN
θ value	7.58209e-15 (rank : 94)	NC score	0.857398 (rank : 21)
Query Neighborhood Hits	417	Target Neighborhood Hits	291	Shared Neighborhood Hits	287
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

BARD1_MOUSE
θ value	1.29331e-14 (rank : 95)	NC score	0.793707 (rank : 110)
Query Neighborhood Hits	417	Target Neighborhood Hits	411	Shared Neighborhood Hits	288
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

EZH2_MOUSE
θ value	1.29331e-14 (rank : 96)	NC score	0.330878 (rank : 284)
Query Neighborhood Hits	417	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

BCL3_MOUSE
θ value	2.20605e-14 (rank : 97)	NC score	0.827393 (rank : 59)
Query Neighborhood Hits	417	Target Neighborhood Hits	388	Shared Neighborhood Hits	282
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

MYPT2_HUMAN
θ value	2.20605e-14 (rank : 98)	NC score	0.798288 (rank : 102)
Query Neighborhood Hits	417	Target Neighborhood Hits	707	Shared Neighborhood Hits	301
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

AN30A_HUMAN
θ value	2.88119e-14 (rank : 99)	NC score	0.594227 (rank : 199)
Query Neighborhood Hits	417	Target Neighborhood Hits	1119	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

HRX_HUMAN
θ value	2.88119e-14 (rank : 100)	NC score	0.266641 (rank : 301)
Query Neighborhood Hits	417	Target Neighborhood Hits	825	Shared Neighborhood Hits	63
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ASB5_HUMAN
θ value	3.76295e-14 (rank : 101)	NC score	0.808164 (rank : 95)
Query Neighborhood Hits	417	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR21_HUMAN
θ value	4.91457e-14 (rank : 102)	NC score	0.735169 (rank : 147)
Query Neighborhood Hits	417	Target Neighborhood Hits	864	Shared Neighborhood Hits	302
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ILK1_HUMAN
θ value	4.91457e-14 (rank : 103)	NC score	0.505925 (rank : 228)
Query Neighborhood Hits	417	Target Neighborhood Hits	857	Shared Neighborhood Hits	284
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	4.91457e-14 (rank : 104)	NC score	0.523797 (rank : 223)
Query Neighborhood Hits	417	Target Neighborhood Hits	848	Shared Neighborhood Hits	284
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ANKR7_HUMAN
θ value	6.41864e-14 (rank : 105)	NC score	0.828192 (rank : 58)
Query Neighborhood Hits	417	Target Neighborhood Hits	286	Shared Neighborhood Hits	283
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR12_HUMAN
θ value	6.41864e-14 (rank : 106)	NC score	0.708949 (rank : 159)
Query Neighborhood Hits	417	Target Neighborhood Hits	1081	Shared Neighborhood Hits	304
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ASB11_HUMAN
θ value	6.41864e-14 (rank : 107)	NC score	0.809285 (rank : 91)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MYPT1_HUMAN
θ value	6.41864e-14 (rank : 108)	NC score	0.797576 (rank : 104)
Query Neighborhood Hits	417	Target Neighborhood Hits	723	Shared Neighborhood Hits	304
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	6.41864e-14 (rank : 109)	NC score	0.815674 (rank : 75)
Query Neighborhood Hits	417	Target Neighborhood Hits	539	Shared Neighborhood Hits	301
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

POT15_HUMAN
θ value	6.41864e-14 (rank : 110)	NC score	0.734764 (rank : 149)
Query Neighborhood Hits	417	Target Neighborhood Hits	893	Shared Neighborhood Hits	298
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RFXK_MOUSE
θ value	6.41864e-14 (rank : 111)	NC score	0.817278 (rank : 73)
Query Neighborhood Hits	417	Target Neighborhood Hits	273	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB5_MOUSE
θ value	8.38298e-14 (rank : 112)	NC score	0.805230 (rank : 96)
Query Neighborhood Hits	417	Target Neighborhood Hits	266	Shared Neighborhood Hits	260
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

A20A1_HUMAN
θ value	1.09485e-13 (rank : 113)	NC score	0.674684 (rank : 180)
Query Neighborhood Hits	417	Target Neighborhood Hits	698	Shared Neighborhood Hits	277
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	1.09485e-13 (rank : 114)	NC score	0.675825 (rank : 179)
Query Neighborhood Hits	417	Target Neighborhood Hits	716	Shared Neighborhood Hits	283
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ASB9_HUMAN
θ value	1.09485e-13 (rank : 115)	NC score	0.809586 (rank : 90)
Query Neighborhood Hits	417	Target Neighborhood Hits	267	Shared Neighborhood Hits	258
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

BARD1_HUMAN
θ value	1.09485e-13 (rank : 116)	NC score	0.793788 (rank : 109)
Query Neighborhood Hits	417	Target Neighborhood Hits	427	Shared Neighborhood Hits	298
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ILK_MOUSE
θ value	1.09485e-13 (rank : 117)	NC score	0.504387 (rank : 229)
Query Neighborhood Hits	417	Target Neighborhood Hits	858	Shared Neighborhood Hits	284
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

SHAN1_HUMAN
θ value	1.09485e-13 (rank : 118)	NC score	0.703491 (rank : 162)
Query Neighborhood Hits	417	Target Neighborhood Hits	1041	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

GABP2_HUMAN
θ value	1.42992e-13 (rank : 119)	NC score	0.838213 (rank : 49)
Query Neighborhood Hits	417	Target Neighborhood Hits	454	Shared Neighborhood Hits	292
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	1.42992e-13 (rank : 120)	NC score	0.840159 (rank : 46)
Query Neighborhood Hits	417	Target Neighborhood Hits	429	Shared Neighborhood Hits	294
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

MLL3_HUMAN
θ value	1.42992e-13 (rank : 121)	NC score	0.205335 (rank : 312)
Query Neighborhood Hits	417	Target Neighborhood Hits	1644	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ANR49_MOUSE
θ value	1.86753e-13 (rank : 122)	NC score	0.850314 (rank : 31)
Query Neighborhood Hits	417	Target Neighborhood Hits	285	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

BCL3_HUMAN
θ value	1.86753e-13 (rank : 123)	NC score	0.830572 (rank : 55)
Query Neighborhood Hits	417	Target Neighborhood Hits	324	Shared Neighborhood Hits	285
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

A20A3_HUMAN
θ value	2.43908e-13 (rank : 124)	NC score	0.676860 (rank : 177)
Query Neighborhood Hits	417	Target Neighborhood Hits	692	Shared Neighborhood Hits	281
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	2.43908e-13 (rank : 125)	NC score	0.671970 (rank : 181)
Query Neighborhood Hits	417	Target Neighborhood Hits	710	Shared Neighborhood Hits	281
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

MLL3_MOUSE
θ value	2.43908e-13 (rank : 126)	NC score	0.211349 (rank : 311)
Query Neighborhood Hits	417	Target Neighborhood Hits	1399	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ANR49_HUMAN
θ value	3.18553e-13 (rank : 127)	NC score	0.844432 (rank : 40)
Query Neighborhood Hits	417	Target Neighborhood Hits	282	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB11_MOUSE
θ value	3.18553e-13 (rank : 128)	NC score	0.810988 (rank : 87)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANR39_MOUSE
θ value	7.09661e-13 (rank : 129)	NC score	0.845339 (rank : 39)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

MLL2_HUMAN
θ value	7.09661e-13 (rank : 130)	NC score	0.204687 (rank : 313)
Query Neighborhood Hits	417	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	7.09661e-13 (rank : 131)	NC score	0.253591 (rank : 303)
Query Neighborhood Hits	417	Target Neighborhood Hits	722	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PA2G6_HUMAN
θ value	7.09661e-13 (rank : 132)	NC score	0.817685 (rank : 72)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR15_HUMAN
θ value	1.2105e-12 (rank : 133)	NC score	0.730255 (rank : 151)
Query Neighborhood Hits	417	Target Neighborhood Hits	478	Shared Neighborhood Hits	280
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

NOTC1_HUMAN
θ value	1.2105e-12 (rank : 134)	NC score	0.410302 (rank : 257)
Query Neighborhood Hits	417	Target Neighborhood Hits	906	Shared Neighborhood Hits	289
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ASB9_MOUSE
θ value	2.0648e-12 (rank : 135)	NC score	0.801308 (rank : 100)
Query Neighborhood Hits	417	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANR39_HUMAN
θ value	2.69671e-12 (rank : 136)	NC score	0.846771 (rank : 36)
Query Neighborhood Hits	417	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKS3_HUMAN
θ value	4.59992e-12 (rank : 137)	NC score	0.822654 (rank : 66)
Query Neighborhood Hits	417	Target Neighborhood Hits	355	Shared Neighborhood Hits	276
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR26_MOUSE
θ value	6.00763e-12 (rank : 138)	NC score	0.462333 (rank : 240)
Query Neighborhood Hits	417	Target Neighborhood Hits	1554	Shared Neighborhood Hits	302
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GABP3_MOUSE
θ value	6.00763e-12 (rank : 139)	NC score	0.836247 (rank : 50)
Query Neighborhood Hits	417	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

NOTC2_HUMAN
θ value	6.00763e-12 (rank : 140)	NC score	0.411182 (rank : 255)
Query Neighborhood Hits	417	Target Neighborhood Hits	1113	Shared Neighborhood Hits	299
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RN5A_HUMAN
θ value	6.00763e-12 (rank : 141)	NC score	0.793616 (rank : 111)
Query Neighborhood Hits	417	Target Neighborhood Hits	608	Shared Neighborhood Hits	284
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ACBD6_HUMAN
θ value	7.84624e-12 (rank : 142)	NC score	0.791240 (rank : 114)
Query Neighborhood Hits	417	Target Neighborhood Hits	304	Shared Neighborhood Hits	288
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKS3_MOUSE
θ value	7.84624e-12 (rank : 143)	NC score	0.825698 (rank : 61)
Query Neighborhood Hits	417	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

POTE8_HUMAN
θ value	7.84624e-12 (rank : 144)	NC score	0.782018 (rank : 127)
Query Neighborhood Hits	417	Target Neighborhood Hits	337	Shared Neighborhood Hits	290
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PP16B_HUMAN
θ value	7.84624e-12 (rank : 145)	NC score	0.803924 (rank : 97)
Query Neighborhood Hits	417	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

NOTC3_HUMAN
θ value	1.02475e-11 (rank : 146)	NC score	0.411181 (rank : 256)
Query Neighborhood Hits	417	Target Neighborhood Hits	1062	Shared Neighborhood Hits	295
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	1.02475e-11 (rank : 147)	NC score	0.413354 (rank : 253)
Query Neighborhood Hits	417	Target Neighborhood Hits	975	Shared Neighborhood Hits	292
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANFY1_MOUSE
θ value	1.33837e-11 (rank : 148)	NC score	0.747716 (rank : 141)
Query Neighborhood Hits	417	Target Neighborhood Hits	480	Shared Neighborhood Hits	296
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR26_HUMAN
θ value	1.33837e-11 (rank : 149)	NC score	0.445270 (rank : 247)
Query Neighborhood Hits	417	Target Neighborhood Hits	1614	Shared Neighborhood Hits	311
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SET1A_HUMAN
θ value	1.33837e-11 (rank : 150)	NC score	0.295964 (rank : 291)
Query Neighborhood Hits	417	Target Neighborhood Hits	690	Shared Neighborhood Hits	71
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ASB16_MOUSE
θ value	1.74796e-11 (rank : 151)	NC score	0.815941 (rank : 74)
Query Neighborhood Hits	417	Target Neighborhood Hits	306	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NOTC2_MOUSE
θ value	1.74796e-11 (rank : 152)	NC score	0.407860 (rank : 260)
Query Neighborhood Hits	417	Target Neighborhood Hits	1069	Shared Neighborhood Hits	297
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PP16B_MOUSE
θ value	2.28291e-11 (rank : 153)	NC score	0.803103 (rank : 98)
Query Neighborhood Hits	417	Target Neighborhood Hits	302	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

PP16A_MOUSE
θ value	2.98157e-11 (rank : 154)	NC score	0.812635 (rank : 82)
Query Neighborhood Hits	417	Target Neighborhood Hits	318	Shared Neighborhood Hits	282
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANFY1_HUMAN
θ value	3.89403e-11 (rank : 155)	NC score	0.745451 (rank : 142)
Query Neighborhood Hits	417	Target Neighborhood Hits	480	Shared Neighborhood Hits	286
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR19_HUMAN
θ value	3.89403e-11 (rank : 156)	NC score	0.778746 (rank : 129)
Query Neighborhood Hits	417	Target Neighborhood Hits	276	Shared Neighborhood Hits	273
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR18_HUMAN
θ value	5.08577e-11 (rank : 157)	NC score	0.619563 (rank : 192)
Query Neighborhood Hits	417	Target Neighborhood Hits	1106	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ACBD6_MOUSE
θ value	6.64225e-11 (rank : 158)	NC score	0.795693 (rank : 107)
Query Neighborhood Hits	417	Target Neighborhood Hits	305	Shared Neighborhood Hits	290
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR11_HUMAN
θ value	6.64225e-11 (rank : 159)	NC score	0.735704 (rank : 146)
Query Neighborhood Hits	417	Target Neighborhood Hits	1289	Shared Neighborhood Hits	314
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANKY2_HUMAN
θ value	8.67504e-11 (rank : 160)	NC score	0.753319 (rank : 137)
Query Neighborhood Hits	417	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR10_MOUSE
θ value	1.133e-10 (rank : 161)	NC score	0.810461 (rank : 88)
Query Neighborhood Hits	417	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR47_HUMAN
θ value	1.133e-10 (rank : 162)	NC score	0.706468 (rank : 160)
Query Neighborhood Hits	417	Target Neighborhood Hits	369	Shared Neighborhood Hits	260
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANKS6_HUMAN
θ value	1.9326e-10 (rank : 163)	NC score	0.813172 (rank : 80)
Query Neighborhood Hits	417	Target Neighborhood Hits	411	Shared Neighborhood Hits	298
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
θ value	5.62301e-10 (rank : 164)	NC score	0.813399 (rank : 78)
Query Neighborhood Hits	417	Target Neighborhood Hits	435	Shared Neighborhood Hits	299
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASB8_HUMAN
θ value	5.62301e-10 (rank : 165)	NC score	0.841410 (rank : 45)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	5.62301e-10 (rank : 166)	NC score	0.841533 (rank : 43)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

AN36A_HUMAN
θ value	7.34386e-10 (rank : 167)	NC score	0.780326 (rank : 128)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	269
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR22_HUMAN
θ value	7.34386e-10 (rank : 168)	NC score	0.810026 (rank : 89)
Query Neighborhood Hits	417	Target Neighborhood Hits	243	Shared Neighborhood Hits	241
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB12_MOUSE
θ value	7.34386e-10 (rank : 169)	NC score	0.786109 (rank : 122)
Query Neighborhood Hits	417	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB16_HUMAN
θ value	7.34386e-10 (rank : 170)	NC score	0.811042 (rank : 86)
Query Neighborhood Hits	417	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANRA2_HUMAN
θ value	9.59137e-10 (rank : 171)	NC score	0.821460 (rank : 68)
Query Neighborhood Hits	417	Target Neighborhood Hits	288	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

MPP8_HUMAN
θ value	9.59137e-10 (rank : 172)	NC score	0.685285 (rank : 171)
Query Neighborhood Hits	417	Target Neighborhood Hits	948	Shared Neighborhood Hits	284
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OSTF1_MOUSE
θ value	9.59137e-10 (rank : 173)	NC score	0.650640 (rank : 186)
Query Neighborhood Hits	417	Target Neighborhood Hits	467	Shared Neighborhood Hits	258
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ASB7_HUMAN
θ value	1.25267e-09 (rank : 174)	NC score	0.838896 (rank : 48)
Query Neighborhood Hits	417	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	1.25267e-09 (rank : 175)	NC score	0.839062 (rank : 47)
Query Neighborhood Hits	417	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

NFKB1_HUMAN
θ value	1.25267e-09 (rank : 176)	NC score	0.700958 (rank : 165)
Query Neighborhood Hits	417	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANRA2_MOUSE
θ value	1.63604e-09 (rank : 177)	NC score	0.820351 (rank : 69)
Query Neighborhood Hits	417	Target Neighborhood Hits	287	Shared Neighborhood Hits	278
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASZ1_MOUSE
θ value	1.63604e-09 (rank : 178)	NC score	0.821941 (rank : 67)
Query Neighborhood Hits	417	Target Neighborhood Hits	319	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKY2_MOUSE
θ value	2.13673e-09 (rank : 179)	NC score	0.725760 (rank : 152)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	266
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

IKBA_MOUSE
θ value	2.13673e-09 (rank : 180)	NC score	0.782984 (rank : 126)
Query Neighborhood Hits	417	Target Neighborhood Hits	283	Shared Neighborhood Hits	272
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

NFKB1_MOUSE
θ value	2.13673e-09 (rank : 181)	NC score	0.701533 (rank : 163)
Query Neighborhood Hits	417	Target Neighborhood Hits	300	Shared Neighborhood Hits	270
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR10_HUMAN
θ value	2.79066e-09 (rank : 182)	NC score	0.808859 (rank : 93)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASZ1_HUMAN
θ value	2.79066e-09 (rank : 183)	NC score	0.819284 (rank : 70)
Query Neighborhood Hits	417	Target Neighborhood Hits	341	Shared Neighborhood Hits	278
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

IKBA_HUMAN
θ value	2.79066e-09 (rank : 184)	NC score	0.794301 (rank : 108)
Query Neighborhood Hits	417	Target Neighborhood Hits	280	Shared Neighborhood Hits	271
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBE_HUMAN
θ value	2.79066e-09 (rank : 185)	NC score	0.763632 (rank : 134)
Query Neighborhood Hits	417	Target Neighborhood Hits	288	Shared Neighborhood Hits	269
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

MTPN_MOUSE
θ value	2.79066e-09 (rank : 186)	NC score	0.833785 (rank : 52)
Query Neighborhood Hits	417	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANR47_MOUSE
θ value	3.64472e-09 (rank : 187)	NC score	0.721320 (rank : 153)
Query Neighborhood Hits	417	Target Neighborhood Hits	350	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFKB2_HUMAN
θ value	3.64472e-09 (rank : 188)	NC score	0.701328 (rank : 164)
Query Neighborhood Hits	417	Target Neighborhood Hits	325	Shared Neighborhood Hits	279
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASB12_HUMAN
θ value	6.21693e-09 (rank : 189)	NC score	0.787673 (rank : 119)
Query Neighborhood Hits	417	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB4_HUMAN
θ value	6.21693e-09 (rank : 190)	NC score	0.792347 (rank : 113)
Query Neighborhood Hits	417	Target Neighborhood Hits	264	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

MTPN_HUMAN
θ value	8.11959e-09 (rank : 191)	NC score	0.830634 (rank : 54)
Query Neighborhood Hits	417	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

CDN2C_HUMAN
θ value	1.38499e-08 (rank : 192)	NC score	0.823379 (rank : 64)
Query Neighborhood Hits	417	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ASB4_MOUSE
θ value	1.80886e-08 (rank : 193)	NC score	0.790731 (rank : 115)
Query Neighborhood Hits	417	Target Neighborhood Hits	265	Shared Neighborhood Hits	257
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

NFKB2_MOUSE
θ value	1.80886e-08 (rank : 194)	NC score	0.685003 (rank : 172)
Query Neighborhood Hits	417	Target Neighborhood Hits	326	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

OSBL1_HUMAN
θ value	1.80886e-08 (rank : 195)	NC score	0.650906 (rank : 185)
Query Neighborhood Hits	417	Target Neighborhood Hits	368	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

CENB2_HUMAN
θ value	2.36244e-08 (rank : 196)	NC score	0.538788 (rank : 217)
Query Neighborhood Hits	417	Target Neighborhood Hits	425	Shared Neighborhood Hits	251
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

USH1G_HUMAN
θ value	2.36244e-08 (rank : 197)	NC score	0.764224 (rank : 133)
Query Neighborhood Hits	417	Target Neighborhood Hits	267	Shared Neighborhood Hits	262
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	2.36244e-08 (rank : 198)	NC score	0.764352 (rank : 132)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ASPP2_HUMAN
θ value	3.08544e-08 (rank : 199)	NC score	0.561932 (rank : 207)
Query Neighborhood Hits	417	Target Neighborhood Hits	1156	Shared Neighborhood Hits	285
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

OSTF1_HUMAN
θ value	3.08544e-08 (rank : 200)	NC score	0.634945 (rank : 190)
Query Neighborhood Hits	417	Target Neighborhood Hits	466	Shared Neighborhood Hits	256
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSBL1_MOUSE
θ value	4.0297e-08 (rank : 201)	NC score	0.639633 (rank : 188)
Query Neighborhood Hits	417	Target Neighborhood Hits	336	Shared Neighborhood Hits	280
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR25_HUMAN
θ value	6.87365e-08 (rank : 202)	NC score	0.679497 (rank : 174)
Query Neighborhood Hits	417	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

CDN2C_MOUSE
θ value	6.87365e-08 (rank : 203)	NC score	0.822816 (rank : 65)
Query Neighborhood Hits	417	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

NOTC1_MOUSE
θ value	6.87365e-08 (rank : 204)	NC score	0.350379 (rank : 273)
Query Neighborhood Hits	417	Target Neighborhood Hits	916	Shared Neighborhood Hits	270
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

IKBE_MOUSE
θ value	8.97725e-08 (rank : 205)	NC score	0.783359 (rank : 125)
Query Neighborhood Hits	417	Target Neighborhood Hits	308	Shared Neighborhood Hits	273
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

CD2A1_MOUSE
θ value	1.53129e-07 (rank : 206)	NC score	0.688182 (rank : 170)
Query Neighborhood Hits	417	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

KRIT1_MOUSE
θ value	1.53129e-07 (rank : 207)	NC score	0.676129 (rank : 178)
Query Neighborhood Hits	417	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

DDFL1_HUMAN
θ value	1.99992e-07 (rank : 208)	NC score	0.374655 (rank : 268)
Query Neighborhood Hits	417	Target Neighborhood Hits	353	Shared Neighborhood Hits	230
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

ASB14_HUMAN
θ value	2.61198e-07 (rank : 209)	NC score	0.551525 (rank : 210)
Query Neighborhood Hits	417	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CDN2D_HUMAN
θ value	3.41135e-07 (rank : 210)	NC score	0.808201 (rank : 94)
Query Neighborhood Hits	417	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CLPB_MOUSE
θ value	3.41135e-07 (rank : 211)	NC score	0.691115 (rank : 168)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	247
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

KRIT1_HUMAN
θ value	4.45536e-07 (rank : 212)	NC score	0.665203 (rank : 183)
Query Neighborhood Hits	417	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ASB1_MOUSE
θ value	5.81887e-07 (rank : 213)	NC score	0.784719 (rank : 124)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR38_HUMAN
θ value	7.59969e-07 (rank : 214)	NC score	0.659600 (rank : 184)
Query Neighborhood Hits	417	Target Neighborhood Hits	443	Shared Neighborhood Hits	243
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASB1_HUMAN
θ value	7.59969e-07 (rank : 215)	NC score	0.787417 (rank : 120)
Query Neighborhood Hits	417	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENB1_HUMAN
θ value	7.59969e-07 (rank : 216)	NC score	0.544209 (rank : 214)
Query Neighborhood Hits	417	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

SNCAP_HUMAN
θ value	9.92553e-07 (rank : 217)	NC score	0.703866 (rank : 161)
Query Neighborhood Hits	417	Target Neighborhood Hits	313	Shared Neighborhood Hits	239
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANS4B_MOUSE
θ value	1.29631e-06 (rank : 218)	NC score	0.744740 (rank : 143)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASPP1_MOUSE
θ value	1.29631e-06 (rank : 219)	NC score	0.529651 (rank : 221)
Query Neighborhood Hits	417	Target Neighborhood Hits	1244	Shared Neighborhood Hits	281
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CDN2D_MOUSE
θ value	1.29631e-06 (rank : 220)	NC score	0.798783 (rank : 101)
Query Neighborhood Hits	417	Target Neighborhood Hits	267	Shared Neighborhood Hits	266
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR32_MOUSE
θ value	1.69304e-06 (rank : 221)	NC score	0.742707 (rank : 144)
Query Neighborhood Hits	417	Target Neighborhood Hits	285	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR38_MOUSE
θ value	1.69304e-06 (rank : 222)	NC score	0.636816 (rank : 189)
Query Neighborhood Hits	417	Target Neighborhood Hits	512	Shared Neighborhood Hits	240
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR46_HUMAN
θ value	1.69304e-06 (rank : 223)	NC score	0.795783 (rank : 106)
Query Neighborhood Hits	417	Target Neighborhood Hits	281	Shared Neighborhood Hits	278
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

SETD8_MOUSE
θ value	1.69304e-06 (rank : 224)	NC score	0.281491 (rank : 296)
Query Neighborhood Hits	417	Target Neighborhood Hits	131	Shared Neighborhood Hits	28
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

TRPV6_MOUSE
θ value	1.69304e-06 (rank : 225)	NC score	0.537869 (rank : 218)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	258
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR25_MOUSE
θ value	2.21117e-06 (rank : 226)	NC score	0.667914 (rank : 182)
Query Neighborhood Hits	417	Target Neighborhood Hits	398	Shared Neighborhood Hits	274
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

GIT2_MOUSE
θ value	2.88788e-06 (rank : 227)	NC score	0.510009 (rank : 226)
Query Neighborhood Hits	417	Target Neighborhood Hits	323	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

POT14_HUMAN
θ value	2.88788e-06 (rank : 228)	NC score	0.713458 (rank : 157)
Query Neighborhood Hits	417	Target Neighborhood Hits	403	Shared Neighborhood Hits	284
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANS4B_HUMAN
θ value	3.77169e-06 (rank : 229)	NC score	0.755136 (rank : 136)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	261
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

BCOR_MOUSE
θ value	3.77169e-06 (rank : 230)	NC score	0.698098 (rank : 167)
Query Neighborhood Hits	417	Target Neighborhood Hits	521	Shared Neighborhood Hits	284
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR33_HUMAN
θ value	4.92598e-06 (rank : 231)	NC score	0.678101 (rank : 175)
Query Neighborhood Hits	417	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BCOR_HUMAN
θ value	4.92598e-06 (rank : 232)	NC score	0.689849 (rank : 169)
Query Neighborhood Hits	417	Target Neighborhood Hits	609	Shared Neighborhood Hits	290
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

GLSL_HUMAN
θ value	4.92598e-06 (rank : 233)	NC score	0.530257 (rank : 220)
Query Neighborhood Hits	417	Target Neighborhood Hits	211	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

NUD12_MOUSE
θ value	4.92598e-06 (rank : 234)	NC score	0.586292 (rank : 202)
Query Neighborhood Hits	417	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

SETD8_HUMAN
θ value	4.92598e-06 (rank : 235)	NC score	0.278975 (rank : 297)
Query Neighborhood Hits	417	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

GLSL_MOUSE
θ value	6.43352e-06 (rank : 236)	NC score	0.516462 (rank : 224)
Query Neighborhood Hits	417	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANR32_HUMAN
θ value	8.40245e-06 (rank : 237)	NC score	0.750895 (rank : 140)
Query Neighborhood Hits	417	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR46_MOUSE
θ value	8.40245e-06 (rank : 238)	NC score	0.789258 (rank : 118)
Query Neighborhood Hits	417	Target Neighborhood Hits	274	Shared Neighborhood Hits	271
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASPP1_HUMAN
θ value	1.09739e-05 (rank : 239)	NC score	0.541307 (rank : 216)
Query Neighborhood Hits	417	Target Neighborhood Hits	956	Shared Neighborhood Hits	274
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GIT2_HUMAN
θ value	1.09739e-05 (rank : 240)	NC score	0.472606 (rank : 239)
Query Neighborhood Hits	417	Target Neighborhood Hits	381	Shared Neighborhood Hits	246
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

NUD12_HUMAN
θ value	1.43324e-05 (rank : 241)	NC score	0.553460 (rank : 209)
Query Neighborhood Hits	417	Target Neighborhood Hits	222	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

GIT1_HUMAN
θ value	1.87187e-05 (rank : 242)	NC score	0.490662 (rank : 234)
Query Neighborhood Hits	417	Target Neighborhood Hits	336	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

ABTB2_HUMAN
θ value	2.44474e-05 (rank : 243)	NC score	0.576989 (rank : 205)
Query Neighborhood Hits	417	Target Neighborhood Hits	391	Shared Neighborhood Hits	241
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
θ value	2.44474e-05 (rank : 244)	NC score	0.565628 (rank : 206)
Query Neighborhood Hits	417	Target Neighborhood Hits	414	Shared Neighborhood Hits	240
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

HECD1_HUMAN
θ value	2.44474e-05 (rank : 245)	NC score	0.588081 (rank : 200)
Query Neighborhood Hits	417	Target Neighborhood Hits	371	Shared Neighborhood Hits	270
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR37_HUMAN
θ value	3.19293e-05 (rank : 246)	NC score	0.718684 (rank : 154)
Query Neighborhood Hits	417	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

CENB5_HUMAN
θ value	3.19293e-05 (rank : 247)	NC score	0.543904 (rank : 215)
Query Neighborhood Hits	417	Target Neighborhood Hits	395	Shared Neighborhood Hits	263
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

POT22_HUMAN
θ value	4.1701e-05 (rank : 248)	NC score	0.677166 (rank : 176)
Query Neighborhood Hits	417	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR37_MOUSE
θ value	5.44631e-05 (rank : 249)	NC score	0.699210 (rank : 166)
Query Neighborhood Hits	417	Target Neighborhood Hits	237	Shared Neighborhood Hits	236
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

GIT1_MOUSE
θ value	7.1131e-05 (rank : 250)	NC score	0.491234 (rank : 233)
Query Neighborhood Hits	417	Target Neighborhood Hits	341	Shared Neighborhood Hits	246
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

AN13B_HUMAN
θ value	0.000121331 (rank : 251)	NC score	0.509773 (rank : 227)
Query Neighborhood Hits	417	Target Neighborhood Hits	265	Shared Neighborhood Hits	252
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.000121331 (rank : 252)	NC score	0.510352 (rank : 225)
Query Neighborhood Hits	417	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CDN2B_MOUSE
θ value	0.000158464 (rank : 253)	NC score	0.643770 (rank : 187)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

GLSK_HUMAN
θ value	0.000158464 (rank : 254)	NC score	0.481123 (rank : 237)
Query Neighborhood Hits	417	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

TEX14_MOUSE
θ value	0.000158464 (rank : 255)	NC score	0.384276 (rank : 264)
Query Neighborhood Hits	417	Target Neighborhood Hits	1333	Shared Neighborhood Hits	272
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CT086_HUMAN
θ value	0.00020696 (rank : 256)	NC score	0.787147 (rank : 121)
Query Neighborhood Hits	417	Target Neighborhood Hits	277	Shared Neighborhood Hits	271
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

IASPP_HUMAN
θ value	0.00020696 (rank : 257)	NC score	0.549248 (rank : 211)
Query Neighborhood Hits	417	Target Neighborhood Hits	688	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANR40_HUMAN
θ value	0.000461057 (rank : 258)	NC score	0.587667 (rank : 201)
Query Neighborhood Hits	417	Target Neighborhood Hits	224	Shared Neighborhood Hits	199
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	0.000461057 (rank : 259)	NC score	0.585803 (rank : 203)
Query Neighborhood Hits	417	Target Neighborhood Hits	228	Shared Neighborhood Hits	203
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR43_HUMAN
θ value	0.000461057 (rank : 260)	NC score	0.604207 (rank : 195)
Query Neighborhood Hits	417	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
θ value	0.000461057 (rank : 261)	NC score	0.605789 (rank : 194)
Query Neighborhood Hits	417	Target Neighborhood Hits	196	Shared Neighborhood Hits	195
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

TRPV3_MOUSE
θ value	0.000602161 (rank : 262)	NC score	0.239718 (rank : 305)
Query Neighborhood Hits	417	Target Neighborhood Hits	188	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

CD2A1_HUMAN
θ value	0.000786445 (rank : 263)	NC score	0.610166 (rank : 193)
Query Neighborhood Hits	417	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

DDFL1_MOUSE
θ value	0.000786445 (rank : 264)	NC score	0.456549 (rank : 243)
Query Neighborhood Hits	417	Target Neighborhood Hits	324	Shared Neighborhood Hits	250
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

ANR33_MOUSE
θ value	0.00102713 (rank : 265)	NC score	0.683434 (rank : 173)
Query Neighborhood Hits	417	Target Neighborhood Hits	225	Shared Neighborhood Hits	223
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CLPB_HUMAN
θ value	0.00102713 (rank : 266)	NC score	0.598729 (rank : 197)
Query Neighborhood Hits	417	Target Neighborhood Hits	265	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR43_MOUSE
θ value	0.00134147 (rank : 267)	NC score	0.597716 (rank : 198)
Query Neighborhood Hits	417	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

DGKZ_MOUSE
θ value	0.00175202 (rank : 268)	NC score	0.354632 (rank : 271)
Query Neighborhood Hits	417	Target Neighborhood Hits	542	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

TRPV3_HUMAN
θ value	0.00175202 (rank : 269)	NC score	0.240205 (rank : 304)
Query Neighborhood Hits	417	Target Neighborhood Hits	198	Shared Neighborhood Hits	148
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

CENG1_MOUSE
θ value	0.00298849 (rank : 270)	NC score	0.348793 (rank : 274)
Query Neighborhood Hits	417	Target Neighborhood Hits	531	Shared Neighborhood Hits	243
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

TRPV6_HUMAN
θ value	0.00298849 (rank : 271)	NC score	0.453767 (rank : 245)
Query Neighborhood Hits	417	Target Neighborhood Hits	262	Shared Neighborhood Hits	231
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

IASPP_MOUSE
θ value	0.00390308 (rank : 272)	NC score	0.500823 (rank : 231)
Query Neighborhood Hits	417	Target Neighborhood Hits	1024	Shared Neighborhood Hits	274
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

DGKZ_HUMAN
θ value	0.00509761 (rank : 273)	NC score	0.373029 (rank : 269)
Query Neighborhood Hits	417	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CT012_HUMAN
θ value	0.00665767 (rank : 274)	NC score	0.422263 (rank : 251)
Query Neighborhood Hits	417	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

ASB6_MOUSE
θ value	0.00869519 (rank : 275)	NC score	0.711406 (rank : 158)
Query Neighborhood Hits	417	Target Neighborhood Hits	264	Shared Neighborhood Hits	245
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CT012_MOUSE
θ value	0.00869519 (rank : 276)	NC score	0.458410 (rank : 242)
Query Neighborhood Hits	417	Target Neighborhood Hits	229	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DDEF2_HUMAN
θ value	0.00869519 (rank : 277)	NC score	0.384047 (rank : 265)
Query Neighborhood Hits	417	Target Neighborhood Hits	599	Shared Neighborhood Hits	234
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CENG1_HUMAN
θ value	0.0113563 (rank : 278)	NC score	0.346422 (rank : 276)
Query Neighborhood Hits	417	Target Neighborhood Hits	544	Shared Neighborhood Hits	243
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

IKBB_HUMAN
θ value	0.0113563 (rank : 279)	NC score	0.735141 (rank : 148)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

TRPV5_HUMAN
θ value	0.0113563 (rank : 280)	NC score	0.454407 (rank : 244)
Query Neighborhood Hits	417	Target Neighborhood Hits	261	Shared Neighborhood Hits	230
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ABTB1_MOUSE
θ value	0.0148317 (rank : 281)	NC score	0.320593 (rank : 287)
Query Neighborhood Hits	417	Target Neighborhood Hits	349	Shared Neighborhood Hits	177
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ANR45_MOUSE
θ value	0.0148317 (rank : 282)	NC score	0.584373 (rank : 204)
Query Neighborhood Hits	417	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

DDEF2_MOUSE
θ value	0.0148317 (rank : 283)	NC score	0.381033 (rank : 266)
Query Neighborhood Hits	417	Target Neighborhood Hits	625	Shared Neighborhood Hits	241
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKI_HUMAN
θ value	0.0148317 (rank : 284)	NC score	0.337588 (rank : 280)
Query Neighborhood Hits	417	Target Neighborhood Hits	609	Shared Neighborhood Hits	214
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

LRRK1_MOUSE
θ value	0.0148317 (rank : 285)	NC score	0.084318 (rank : 334)
Query Neighborhood Hits	417	Target Neighborhood Hits	1267	Shared Neighborhood Hits	127
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TEX14_HUMAN
θ value	0.0148317 (rank : 286)	NC score	0.377800 (rank : 267)
Query Neighborhood Hits	417	Target Neighborhood Hits	1103	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

AN13C_HUMAN
θ value	0.0193708 (rank : 287)	NC score	0.497556 (rank : 232)
Query Neighborhood Hits	417	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR45_HUMAN
θ value	0.0193708 (rank : 288)	NC score	0.548840 (rank : 212)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB6_HUMAN
θ value	0.0252991 (rank : 289)	NC score	0.715339 (rank : 155)
Query Neighborhood Hits	417	Target Neighborhood Hits	256	Shared Neighborhood Hits	247
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLR59_HUMAN
θ value	0.0252991 (rank : 290)	NC score	0.290559 (rank : 292)
Query Neighborhood Hits	417	Target Neighborhood Hits	163	Shared Neighborhood Hits	137
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

TRPV5_MOUSE
θ value	0.0252991 (rank : 291)	NC score	0.482366 (rank : 236)
Query Neighborhood Hits	417	Target Neighborhood Hits	278	Shared Neighborhood Hits	251
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CMTA1_HUMAN
θ value	0.0330416 (rank : 292)	NC score	0.200063 (rank : 315)
Query Neighborhood Hits	417	Target Neighborhood Hits	217	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

MUC13_MOUSE
θ value	0.0330416 (rank : 293)	NC score	0.052602 (rank : 341)
Query Neighborhood Hits	417	Target Neighborhood Hits	447	Shared Neighborhood Hits	24
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

RIF1_MOUSE
θ value	0.0330416 (rank : 294)	NC score	0.033511 (rank : 361)
Query Neighborhood Hits	417	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ABTB1_HUMAN
θ value	0.0431538 (rank : 295)	NC score	0.278491 (rank : 299)
Query Neighborhood Hits	417	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ANKY1_HUMAN
θ value	0.0431538 (rank : 296)	NC score	0.527378 (rank : 222)
Query Neighborhood Hits	417	Target Neighborhood Hits	248	Shared Neighborhood Hits	205
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ACINU_HUMAN
θ value	0.0563607 (rank : 297)	NC score	0.040921 (rank : 354)
Query Neighborhood Hits	417	Target Neighborhood Hits	828	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AN13C_MOUSE
θ value	0.0563607 (rank : 298)	NC score	0.485964 (rank : 235)
Query Neighborhood Hits	417	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

IKBB_MOUSE
θ value	0.0563607 (rank : 299)	NC score	0.735962 (rank : 145)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	274
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

INP5E_HUMAN
θ value	0.0563607 (rank : 300)	NC score	0.018664 (rank : 383)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

TRPC1_HUMAN
θ value	0.0563607 (rank : 301)	NC score	0.076184 (rank : 335)
Query Neighborhood Hits	417	Target Neighborhood Hits	91	Shared Neighborhood Hits	57
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC6_HUMAN
θ value	0.0736092 (rank : 302)	NC score	0.136384 (rank : 320)
Query Neighborhood Hits	417	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

ANR41_HUMAN
θ value	0.0961366 (rank : 303)	NC score	0.714330 (rank : 156)
Query Neighborhood Hits	417	Target Neighborhood Hits	332	Shared Neighborhood Hits	254
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

DSPP_MOUSE
θ value	0.0961366 (rank : 304)	NC score	0.040967 (rank : 353)
Query Neighborhood Hits	417	Target Neighborhood Hits	491	Shared Neighborhood Hits	42
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_MOUSE
θ value	0.0961366 (rank : 305)	NC score	0.041939 (rank : 352)
Query Neighborhood Hits	417	Target Neighborhood Hits	946	Shared Neighborhood Hits	58
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TRPC1_MOUSE
θ value	0.0961366 (rank : 306)	NC score	0.070890 (rank : 336)
Query Neighborhood Hits	417	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC3_HUMAN
θ value	0.0961366 (rank : 307)	NC score	0.117596 (rank : 324)
Query Neighborhood Hits	417	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC7_MOUSE
θ value	0.0961366 (rank : 308)	NC score	0.102073 (rank : 328)
Query Neighborhood Hits	417	Target Neighborhood Hits	114	Shared Neighborhood Hits	79
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

NTHL1_HUMAN
θ value	0.163984 (rank : 309)	NC score	0.022858 (rank : 377)
Query Neighborhood Hits	417	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

AN13A_HUMAN
θ value	0.21417 (rank : 310)	NC score	0.441868 (rank : 248)
Query Neighborhood Hits	417	Target Neighborhood Hits	243	Shared Neighborhood Hits	227
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

TRPC4_HUMAN
θ value	0.21417 (rank : 311)	NC score	0.092753 (rank : 332)
Query Neighborhood Hits	417	Target Neighborhood Hits	140	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0.21417 (rank : 312)	NC score	0.092780 (rank : 331)
Query Neighborhood Hits	417	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC7_HUMAN
θ value	0.21417 (rank : 313)	NC score	0.101458 (rank : 329)
Query Neighborhood Hits	417	Target Neighborhood Hits	123	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TCAL5_HUMAN
θ value	0.279714 (rank : 314)	NC score	0.034735 (rank : 359)
Query Neighborhood Hits	417	Target Neighborhood Hits	806	Shared Neighborhood Hits	44
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

DDEF1_MOUSE
θ value	0.365318 (rank : 315)	NC score	0.286979 (rank : 293)
Query Neighborhood Hits	417	Target Neighborhood Hits	592	Shared Neighborhood Hits	194
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NSBP1_MOUSE
θ value	0.365318 (rank : 316)	NC score	0.034290 (rank : 360)
Query Neighborhood Hits	417	Target Neighborhood Hits	681	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

TRPC3_MOUSE
θ value	0.365318 (rank : 317)	NC score	0.108713 (rank : 326)
Query Neighborhood Hits	417	Target Neighborhood Hits	131	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

CENG2_HUMAN
θ value	0.47712 (rank : 318)	NC score	0.340853 (rank : 277)
Query Neighborhood Hits	417	Target Neighborhood Hits	471	Shared Neighborhood Hits	253
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENPR_MOUSE
θ value	0.47712 (rank : 319)	NC score	0.026866 (rank : 370)
Query Neighborhood Hits	417	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQ82, Q3TLR0, Q3TNR4	Gene names	Itgb3bp, Cenpr, Nrif3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3).

DSPP_HUMAN
θ value	0.47712 (rank : 320)	NC score	0.038072 (rank : 356)
Query Neighborhood Hits	417	Target Neighborhood Hits	645	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FOG1_MOUSE
θ value	0.47712 (rank : 321)	NC score	0.002489 (rank : 421)
Query Neighborhood Hits	417	Target Neighborhood Hits	1237	Shared Neighborhood Hits	40
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PRR12_HUMAN
θ value	0.47712 (rank : 322)	NC score	0.040451 (rank : 355)
Query Neighborhood Hits	417	Target Neighborhood Hits	460	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CENG2_MOUSE
θ value	0.62314 (rank : 323)	NC score	0.338347 (rank : 279)
Query Neighborhood Hits	417	Target Neighborhood Hits	463	Shared Neighborhood Hits	250
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

IKBL_HUMAN
θ value	0.62314 (rank : 324)	NC score	0.327248 (rank : 285)
Query Neighborhood Hits	417	Target Neighborhood Hits	168	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	0.62314 (rank : 325)	NC score	0.322288 (rank : 286)
Query Neighborhood Hits	417	Target Neighborhood Hits	196	Shared Neighborhood Hits	143
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

NALP5_MOUSE
θ value	0.62314 (rank : 326)	NC score	0.011529 (rank : 395)
Query Neighborhood Hits	417	Target Neighborhood Hits	560	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PCGF2_HUMAN
θ value	0.62314 (rank : 327)	NC score	0.021567 (rank : 378)
Query Neighborhood Hits	417	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.62314 (rank : 328)	NC score	0.020706 (rank : 380)
Query Neighborhood Hits	417	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	0.62314 (rank : 329)	NC score	0.026101 (rank : 372)
Query Neighborhood Hits	417	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.62314 (rank : 330)	NC score	0.026058 (rank : 373)
Query Neighborhood Hits	417	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

TRPC6_MOUSE
θ value	0.813845 (rank : 331)	NC score	0.108362 (rank : 327)
Query Neighborhood Hits	417	Target Neighborhood Hits	171	Shared Neighborhood Hits	95
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

AKA12_HUMAN
θ value	1.06291 (rank : 332)	NC score	0.048774 (rank : 350)
Query Neighborhood Hits	417	Target Neighborhood Hits	825	Shared Neighborhood Hits	54
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DMP1_HUMAN
θ value	1.06291 (rank : 333)	NC score	0.047044 (rank : 351)
Query Neighborhood Hits	417	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

MINT_MOUSE
θ value	1.06291 (rank : 334)	NC score	0.027556 (rank : 369)
Query Neighborhood Hits	417	Target Neighborhood Hits	1514	Shared Neighborhood Hits	70
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SMG5_HUMAN
θ value	1.06291 (rank : 335)	NC score	0.013378 (rank : 393)
Query Neighborhood Hits	417	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

TRPV2_HUMAN
θ value	1.06291 (rank : 336)	NC score	0.200413 (rank : 314)
Query Neighborhood Hits	417	Target Neighborhood Hits	130	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ZFY2_MOUSE
θ value	1.06291 (rank : 337)	NC score	-0.011646 (rank : 434)
Query Neighborhood Hits	417	Target Neighborhood Hits	795	Shared Neighborhood Hits	21
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

BAT4_MOUSE
θ value	1.38821 (rank : 338)	NC score	0.266932 (rank : 300)
Query Neighborhood Hits	417	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CD2L1_HUMAN
θ value	1.38821 (rank : 339)	NC score	0.004829 (rank : 414)
Query Neighborhood Hits	417	Target Neighborhood Hits	1467	Shared Neighborhood Hits	69
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

DCDC2_MOUSE
θ value	1.38821 (rank : 340)	NC score	0.015814 (rank : 388)
Query Neighborhood Hits	417	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

FILA_HUMAN
θ value	1.38821 (rank : 341)	NC score	0.025390 (rank : 374)
Query Neighborhood Hits	417	Target Neighborhood Hits	685	Shared Neighborhood Hits	41
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LEO1_HUMAN
θ value	1.38821 (rank : 342)	NC score	0.038020 (rank : 357)
Query Neighborhood Hits	417	Target Neighborhood Hits	958	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MCPH1_MOUSE
θ value	1.38821 (rank : 343)	NC score	0.030257 (rank : 366)
Query Neighborhood Hits	417	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

SMOC1_HUMAN
θ value	1.38821 (rank : 344)	NC score	0.006147 (rank : 409)
Query Neighborhood Hits	417	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SPRL1_MOUSE
θ value	1.38821 (rank : 345)	NC score	0.024555 (rank : 375)
Query Neighborhood Hits	417	Target Neighborhood Hits	403	Shared Neighborhood Hits	40
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TRPC5_HUMAN
θ value	1.38821 (rank : 346)	NC score	0.091922 (rank : 333)
Query Neighborhood Hits	417	Target Neighborhood Hits	122	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	1.38821 (rank : 347)	NC score	0.093176 (rank : 330)
Query Neighborhood Hits	417	Target Neighborhood Hits	124	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPV1_MOUSE
θ value	1.38821 (rank : 348)	NC score	0.234377 (rank : 306)
Query Neighborhood Hits	417	Target Neighborhood Hits	189	Shared Neighborhood Hits	161
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ZN524_MOUSE
θ value	1.38821 (rank : 349)	NC score	-0.013096 (rank : 436)
Query Neighborhood Hits	417	Target Neighborhood Hits	712	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0B1, Q9DCQ0	Gene names	Znf524, Zfp524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

AN13A_MOUSE
θ value	1.81305 (rank : 350)	NC score	0.412160 (rank : 254)
Query Neighborhood Hits	417	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CENG3_HUMAN
θ value	1.81305 (rank : 351)	NC score	0.307147 (rank : 290)
Query Neighborhood Hits	417	Target Neighborhood Hits	455	Shared Neighborhood Hits	227
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	1.81305 (rank : 352)	NC score	0.307305 (rank : 289)
Query Neighborhood Hits	417	Target Neighborhood Hits	467	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

FOG1_HUMAN
θ value	1.81305 (rank : 353)	NC score	-0.001725 (rank : 432)
Query Neighborhood Hits	417	Target Neighborhood Hits	981	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

JADE2_HUMAN
θ value	1.81305 (rank : 354)	NC score	0.020956 (rank : 379)
Query Neighborhood Hits	417	Target Neighborhood Hits	199	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

K0427_MOUSE
θ value	1.81305 (rank : 355)	NC score	0.009725 (rank : 399)
Query Neighborhood Hits	417	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

BBS4_HUMAN
θ value	2.36792 (rank : 356)	NC score	0.008637 (rank : 400)
Query Neighborhood Hits	417	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

DDX21_MOUSE
θ value	2.36792 (rank : 357)	NC score	0.006174 (rank : 408)
Query Neighborhood Hits	417	Target Neighborhood Hits	350	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DTX2_MOUSE
θ value	2.36792 (rank : 358)	NC score	0.006704 (rank : 405)
Query Neighborhood Hits	417	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

MYLK_MOUSE
θ value	2.36792 (rank : 359)	NC score	0.008171 (rank : 401)
Query Neighborhood Hits	417	Target Neighborhood Hits	1489	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYO9B_HUMAN
θ value	2.36792 (rank : 360)	NC score	0.005811 (rank : 411)
Query Neighborhood Hits	417	Target Neighborhood Hits	641	Shared Neighborhood Hits	40
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SDPR_MOUSE
θ value	2.36792 (rank : 361)	NC score	0.012395 (rank : 394)
Query Neighborhood Hits	417	Target Neighborhood Hits	485	Shared Neighborhood Hits	24
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TRPV1_HUMAN
θ value	2.36792 (rank : 362)	NC score	0.221476 (rank : 309)
Query Neighborhood Hits	417	Target Neighborhood Hits	184	Shared Neighborhood Hits	153
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

ANKZ1_MOUSE
θ value	3.0926 (rank : 363)	NC score	0.310500 (rank : 288)
Query Neighborhood Hits	417	Target Neighborhood Hits	208	Shared Neighborhood Hits	152
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CMTA2_MOUSE
θ value	3.0926 (rank : 364)	NC score	0.143129 (rank : 319)
Query Neighborhood Hits	417	Target Neighborhood Hits	216	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

FOXC2_HUMAN
θ value	3.0926 (rank : 365)	NC score	-0.000288 (rank : 429)
Query Neighborhood Hits	417	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

INADL_MOUSE
θ value	3.0926 (rank : 366)	NC score	0.001794 (rank : 424)
Query Neighborhood Hits	417	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

RRBP1_MOUSE
θ value	3.0926 (rank : 367)	NC score	0.028804 (rank : 367)
Query Neighborhood Hits	417	Target Neighborhood Hits	1650	Shared Neighborhood Hits	74
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SMC2_HUMAN
θ value	3.0926 (rank : 368)	NC score	0.030280 (rank : 365)
Query Neighborhood Hits	417	Target Neighborhood Hits	1405	Shared Neighborhood Hits	46
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CMTA2_HUMAN
θ value	4.03905 (rank : 369)	NC score	0.155055 (rank : 317)
Query Neighborhood Hits	417	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

EMID2_HUMAN
θ value	4.03905 (rank : 370)	NC score	0.010387 (rank : 398)
Query Neighborhood Hits	417	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

PDIA3_MOUSE
θ value	4.03905 (rank : 371)	NC score	0.003159 (rank : 419)
Query Neighborhood Hits	417	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PMS2_HUMAN
θ value	4.03905 (rank : 372)	NC score	0.006600 (rank : 406)
Query Neighborhood Hits	417	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

SRCA_HUMAN
θ value	4.03905 (rank : 373)	NC score	0.013632 (rank : 391)
Query Neighborhood Hits	417	Target Neighborhood Hits	380	Shared Neighborhood Hits	38
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

THAP3_HUMAN
θ value	4.03905 (rank : 374)	NC score	0.006976 (rank : 404)
Query Neighborhood Hits	417	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WTV1, Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2, Q9Y3H3	Gene names	THAP3
Domain Architecture
Description	THAP domain-containing protein 3.

TP53B_MOUSE
θ value	4.03905 (rank : 375)	NC score	0.027659 (rank : 368)
Query Neighborhood Hits	417	Target Neighborhood Hits	644	Shared Neighborhood Hits	44
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BNC2_HUMAN
θ value	5.27518 (rank : 376)	NC score	0.006461 (rank : 407)
Query Neighborhood Hits	417	Target Neighborhood Hits	439	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BNC2_MOUSE
θ value	5.27518 (rank : 377)	NC score	0.005508 (rank : 412)
Query Neighborhood Hits	417	Target Neighborhood Hits	456	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CHD6_HUMAN
θ value	5.27518 (rank : 378)	NC score	0.005079 (rank : 413)
Query Neighborhood Hits	417	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

GRIN1_MOUSE
θ value	5.27518 (rank : 379)	NC score	0.018118 (rank : 384)
Query Neighborhood Hits	417	Target Neighborhood Hits	337	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HDAC9_HUMAN
θ value	5.27518 (rank : 380)	NC score	0.004360 (rank : 417)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

IWS1_MOUSE
θ value	5.27518 (rank : 381)	NC score	0.052186 (rank : 345)
Query Neighborhood Hits	417	Target Neighborhood Hits	1258	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LIMA1_MOUSE
θ value	5.27518 (rank : 382)	NC score	0.010799 (rank : 397)
Query Neighborhood Hits	417	Target Neighborhood Hits	298	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

LRRK1_HUMAN
θ value	5.27518 (rank : 383)	NC score	0.058258 (rank : 337)
Query Neighborhood Hits	417	Target Neighborhood Hits	1237	Shared Neighborhood Hits	100
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MDN1_HUMAN
θ value	5.27518 (rank : 384)	NC score	0.036108 (rank : 358)
Query Neighborhood Hits	417	Target Neighborhood Hits	662	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NEST_HUMAN
θ value	5.27518 (rank : 385)	NC score	0.023888 (rank : 376)
Query Neighborhood Hits	417	Target Neighborhood Hits	1305	Shared Neighborhood Hits	62
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

OSBL8_HUMAN
θ value	5.27518 (rank : 386)	NC score	0.020468 (rank : 381)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OTU7A_MOUSE
θ value	5.27518 (rank : 387)	NC score	0.005843 (rank : 410)
Query Neighborhood Hits	417	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

REN3A_HUMAN
θ value	5.27518 (rank : 388)	NC score	0.020076 (rank : 382)
Query Neighborhood Hits	417	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

SASH1_MOUSE
θ value	5.27518 (rank : 389)	NC score	0.033147 (rank : 362)
Query Neighborhood Hits	417	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SOX4_MOUSE
θ value	5.27518 (rank : 390)	NC score	0.001089 (rank : 426)
Query Neighborhood Hits	417	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SPEF1_HUMAN
θ value	5.27518 (rank : 391)	NC score	0.007711 (rank : 402)
Query Neighborhood Hits	417	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4P9, Q5JX78	Gene names	SPEF1, C20orf28
Domain Architecture
Description	Sperm flagellar protein 1.

TIF1G_MOUSE
θ value	5.27518 (rank : 392)	NC score	0.013707 (rank : 390)
Query Neighborhood Hits	417	Target Neighborhood Hits	498	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZXDB_HUMAN
θ value	5.27518 (rank : 393)	NC score	-0.012830 (rank : 435)
Query Neighborhood Hits	417	Target Neighborhood Hits	753	Shared Neighborhood Hits	14
SwissProt Accessions	P98169, Q9UBB3	Gene names	ZXDB
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDB.

CLSPN_MOUSE
θ value	6.88961 (rank : 394)	NC score	0.030306 (rank : 364)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

HMX3_MOUSE
θ value	6.88961 (rank : 395)	NC score	-0.007768 (rank : 433)
Query Neighborhood Hits	417	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

IL18R_MOUSE
θ value	6.88961 (rank : 396)	NC score	0.000049 (rank : 428)
Query Neighborhood Hits	417	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q61098	Gene names	Il18r1
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp).

SASH1_HUMAN
θ value	6.88961 (rank : 397)	NC score	0.026840 (rank : 371)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	24
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SC24B_HUMAN
θ value	6.88961 (rank : 398)	NC score	0.004435 (rank : 415)
Query Neighborhood Hits	417	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

VPS72_HUMAN
θ value	6.88961 (rank : 399)	NC score	0.030792 (rank : 363)
Query Neighborhood Hits	417	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VWF_HUMAN
θ value	6.88961 (rank : 400)	NC score	0.017269 (rank : 386)
Query Neighborhood Hits	417	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

5HT7R_MOUSE
θ value	8.99809 (rank : 401)	NC score	-0.013423 (rank : 437)
Query Neighborhood Hits	417	Target Neighborhood Hits	823	Shared Neighborhood Hits	2
SwissProt Accessions	P32304	Gene names	Htr7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

CACB2_HUMAN
θ value	8.99809 (rank : 402)	NC score	0.003150 (rank : 420)
Query Neighborhood Hits	417	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	8.99809 (rank : 403)	NC score	0.002071 (rank : 422)
Query Neighborhood Hits	417	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CAMKV_HUMAN
θ value	8.99809 (rank : 404)	NC score	-0.000487 (rank : 430)
Query Neighborhood Hits	417	Target Neighborhood Hits	1084	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

COBA2_HUMAN
θ value	8.99809 (rank : 405)	NC score	0.003749 (rank : 418)
Query Neighborhood Hits	417	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COBA2_MOUSE
θ value	8.99809 (rank : 406)	NC score	0.001206 (rank : 425)
Query Neighborhood Hits	417	Target Neighborhood Hits	501	Shared Neighborhood Hits	21
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

DDX24_HUMAN
θ value	8.99809 (rank : 407)	NC score	-0.000527 (rank : 431)
Query Neighborhood Hits	417	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

GSLG1_MOUSE
θ value	8.99809 (rank : 408)	NC score	0.004383 (rank : 416)
Query Neighborhood Hits	417	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

MAST4_HUMAN
θ value	8.99809 (rank : 409)	NC score	0.013619 (rank : 392)
Query Neighborhood Hits	417	Target Neighborhood Hits	1804	Shared Neighborhood Hits	76
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MYRIP_HUMAN
θ value	8.99809 (rank : 410)	NC score	0.010916 (rank : 396)
Query Neighborhood Hits	417	Target Neighborhood Hits	269	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PAR3L_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.000088 (rank : 427)
Query Neighborhood Hits	417	Target Neighborhood Hits	297	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDIA3_HUMAN
θ value	8.99809 (rank : 412)	NC score	0.001962 (rank : 423)
Query Neighborhood Hits	417	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

ROCK1_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.016838 (rank : 387)
Query Neighborhood Hits	417	Target Neighborhood Hits	2000	Shared Neighborhood Hits	58
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SG16_MOUSE
θ value	8.99809 (rank : 414)	NC score	0.017820 (rank : 385)
Query Neighborhood Hits	417	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P02815, Q62263	Gene names	Spt1, Spt-1
Domain Architecture	No domain graphic available
Description	16.5 kDa submandibular gland glycoprotein precursor (Salivary protein 1).

TNC6B_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.014019 (rank : 389)
Query Neighborhood Hits	417	Target Neighborhood Hits	256	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TOIP2_HUMAN
θ value	8.99809 (rank : 416)	NC score	0.007473 (rank : 403)
Query Neighborhood Hits	417	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

ZBT11_HUMAN
θ value	8.99809 (rank : 417)	NC score	-0.013933 (rank : 438)
Query Neighborhood Hits	417	Target Neighborhood Hits	873	Shared Neighborhood Hits	16
SwissProt Accessions	O95625	Gene names	ZBTB11
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 11.

ANKF1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.126428 (rank : 321)
Query Neighborhood Hits	417	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.215732 (rank : 310)
Query Neighborhood Hits	417	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.264148 (rank : 302)
Query Neighborhood Hits	417	Target Neighborhood Hits	120	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKZ1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.283683 (rank : 294)
Query Neighborhood Hits	417	Target Neighborhood Hits	236	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

BAT4_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.226099 (rank : 307)
Query Neighborhood Hits	417	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CENA1_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.051259 (rank : 347)
Query Neighborhood Hits	417	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CU081_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.120029 (rank : 323)
Query Neighborhood Hits	417	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

LCE1C_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.052596 (rank : 342)
Query Neighborhood Hits	417	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.055092 (rank : 339)
Query Neighborhood Hits	417	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

MDC1_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.050217 (rank : 348)
Query Neighborhood Hits	417	Target Neighborhood Hits	1446	Shared Neighborhood Hits	77
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RSNL2_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.222828 (rank : 308)
Query Neighborhood Hits	417	Target Neighborhood Hits	136	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.190525 (rank : 316)
Query Neighborhood Hits	417	Target Neighborhood Hits	129	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SMAP1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.050111 (rank : 349)
Query Neighborhood Hits	417	Target Neighborhood Hits	98	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.052534 (rank : 344)
Query Neighborhood Hits	417	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.051344 (rank : 346)
Query Neighborhood Hits	417	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.054040 (rank : 340)
Query Neighborhood Hits	417	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRRM1_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.052572 (rank : 343)
Query Neighborhood Hits	417	Target Neighborhood Hits	966	Shared Neighborhood Hits	60
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRDN_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.057668 (rank : 338)
Query Neighborhood Hits	417	Target Neighborhood Hits	542	Shared Neighborhood Hits	45
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPV2_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.152163 (rank : 318)
Query Neighborhood Hits	417	Target Neighborhood Hits	111	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV4_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.123506 (rank : 322)
Query Neighborhood Hits	417	Target Neighborhood Hits	150	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.110205 (rank : 325)
Query Neighborhood Hits	417	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

EHMT1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	417	Target Neighborhood Hits	417	Shared Neighborhood Hits	417
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_HUMAN
NC score	0.981392 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	417	Target Neighborhood Hits	498	Shared Neighborhood Hits	330
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.965465 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	417	Target Neighborhood Hits	750	Shared Neighborhood Hits	339
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR29_HUMAN
NC score	0.881440 (rank : 4)	θ value	8.36355e-22 (rank : 36)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	290
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.880454 (rank : 5)	θ value	2.87452e-22 (rank : 34)
Query Neighborhood Hits	417	Target Neighborhood Hits	301	Shared Neighborhood Hits	292
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.878837 (rank : 6)	θ value	4.15078e-21 (rank : 38)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.875772 (rank : 7)	θ value	3.74554e-30 (rank : 9)
Query Neighborhood Hits	417	Target Neighborhood Hits	439	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR50_HUMAN
NC score	0.871456 (rank : 8)	θ value	1.6813e-30 (rank : 8)
Query Neighborhood Hits	417	Target Neighborhood Hits	361	Shared Neighborhood Hits	302
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR16_HUMAN
NC score	0.867114 (rank : 9)	θ value	1.24977e-17 (rank : 59)
Query Neighborhood Hits	417	Target Neighborhood Hits	286	Shared Neighborhood Hits	282
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANKR2_MOUSE
NC score	0.865720 (rank : 10)	θ value	1.16704e-23 (rank : 24)
Query Neighborhood Hits	417	Target Neighborhood Hits	312	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR2_HUMAN
NC score	0.862422 (rank : 11)	θ value	8.36355e-22 (rank : 35)
Query Neighborhood Hits	417	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR44_HUMAN
NC score	0.861538 (rank : 12)	θ value	2.77775e-25 (rank : 19)
Query Neighborhood Hits	417	Target Neighborhood Hits	318	Shared Neighborhood Hits	303
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

FANK1_HUMAN
NC score	0.860499 (rank : 13)	θ value	4.29542e-18 (rank : 55)
Query Neighborhood Hits	417	Target Neighborhood Hits	326	Shared Neighborhood Hits	288
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANR23_MOUSE
NC score	0.860259 (rank : 14)	θ value	1.52774e-15 (rank : 86)
Query Neighborhood Hits	417	Target Neighborhood Hits	296	Shared Neighborhood Hits	288
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB3_HUMAN
NC score	0.860047 (rank : 15)	θ value	6.62687e-19 (rank : 47)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

FANK1_MOUSE
NC score	0.859352 (rank : 16)	θ value	2.13179e-17 (rank : 61)
Query Neighborhood Hits	417	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANR28_MOUSE
NC score	0.859351 (rank : 17)	θ value	1.47289e-26 (rank : 14)
Query Neighborhood Hits	417	Target Neighborhood Hits	314	Shared Neighborhood Hits	298
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

INVS_HUMAN
NC score	0.859057 (rank : 18)	θ value	1.5242e-23 (rank : 27)
Query Neighborhood Hits	417	Target Neighborhood Hits	455	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB3_MOUSE
NC score	0.858347 (rank : 19)	θ value	5.60996e-18 (rank : 57)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR28_HUMAN
NC score	0.857930 (rank : 20)	θ value	2.51237e-26 (rank : 15)
Query Neighborhood Hits	417	Target Neighborhood Hits	314	Shared Neighborhood Hits	298
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR23_HUMAN
NC score	0.857398 (rank : 21)	θ value	7.58209e-15 (rank : 94)
Query Neighborhood Hits	417	Target Neighborhood Hits	291	Shared Neighborhood Hits	287
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANKR1_HUMAN
NC score	0.856870 (rank : 22)	θ value	7.82807e-20 (rank : 41)
Query Neighborhood Hits	417	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR42_MOUSE
NC score	0.855908 (rank : 23)	θ value	4.15078e-21 (rank : 37)
Query Neighborhood Hits	417	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANKR1_MOUSE
NC score	0.855320 (rank : 24)	θ value	3.88503e-19 (rank : 43)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	288
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

TNKS1_HUMAN
NC score	0.853597 (rank : 25)	θ value	3.87602e-27 (rank : 13)
Query Neighborhood Hits	417	Target Neighborhood Hits	477	Shared Neighborhood Hits	307
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.853245 (rank : 26)	θ value	9.54697e-26 (rank : 16)
Query Neighborhood Hits	417	Target Neighborhood Hits	361	Shared Neighborhood Hits	301
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ASB10_HUMAN
NC score	0.853004 (rank : 27)	θ value	1.47631e-18 (rank : 48)
Query Neighborhood Hits	417	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

INVS_MOUSE
NC score	0.852276 (rank : 28)	θ value	3.39556e-23 (rank : 28)
Query Neighborhood Hits	417	Target Neighborhood Hits	609	Shared Neighborhood Hits	308
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB2_HUMAN
NC score	0.851835 (rank : 29)	θ value	2.06002e-20 (rank : 40)
Query Neighborhood Hits	417	Target Neighborhood Hits	309	Shared Neighborhood Hits	292
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANK1_HUMAN
NC score	0.850371 (rank : 30)	θ value	2.68423e-28 (rank : 10)
Query Neighborhood Hits	417	Target Neighborhood Hits	416	Shared Neighborhood Hits	308
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR49_MOUSE
NC score	0.850314 (rank : 31)	θ value	1.86753e-13 (rank : 122)
Query Neighborhood Hits	417	Target Neighborhood Hits	285	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR52_MOUSE
NC score	0.849643 (rank : 32)	θ value	5.79196e-23 (rank : 29)
Query Neighborhood Hits	417	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.849440 (rank : 33)	θ value	7.56453e-23 (rank : 30)
Query Neighborhood Hits	417	Target Neighborhood Hits	322	Shared Neighborhood Hits	302
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANK1_MOUSE
NC score	0.849371 (rank : 34)	θ value	2.68423e-28 (rank : 11)
Query Neighborhood Hits	417	Target Neighborhood Hits	430	Shared Neighborhood Hits	309
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ASB10_MOUSE
NC score	0.849276 (rank : 35)	θ value	3.28887e-18 (rank : 54)
Query Neighborhood Hits	417	Target Neighborhood Hits	301	Shared Neighborhood Hits	286
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR39_HUMAN
NC score	0.846771 (rank : 36)	θ value	2.69671e-12 (rank : 136)
Query Neighborhood Hits	417	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR42_HUMAN
NC score	0.846014 (rank : 37)	θ value	3.40345e-15 (rank : 88)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB2_MOUSE
NC score	0.845458 (rank : 38)	θ value	2.5182e-18 (rank : 53)
Query Neighborhood Hits	417	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR39_MOUSE
NC score	0.845339 (rank : 39)	θ value	7.09661e-13 (rank : 129)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR49_HUMAN
NC score	0.844432 (rank : 40)	θ value	3.18553e-13 (rank : 127)
Query Neighborhood Hits	417	Target Neighborhood Hits	282	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB13_MOUSE
NC score	0.843249 (rank : 41)	θ value	3.40345e-15 (rank : 90)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.843069 (rank : 42)	θ value	3.40345e-15 (rank : 89)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB8_MOUSE
NC score	0.841533 (rank : 43)	θ value	5.62301e-10 (rank : 166)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANK3_HUMAN
NC score	0.841433 (rank : 44)	θ value	2.68423e-28 (rank : 12)
Query Neighborhood Hits	417	Target Neighborhood Hits	853	Shared Neighborhood Hits	329
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ASB8_HUMAN
NC score	0.841410 (rank : 45)	θ value	5.62301e-10 (rank : 165)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

GABP2_MOUSE
NC score	0.840159 (rank : 46)	θ value	1.42992e-13 (rank : 120)
Query Neighborhood Hits	417	Target Neighborhood Hits	429	Shared Neighborhood Hits	294
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB7_MOUSE
NC score	0.839062 (rank : 47)	θ value	1.25267e-09 (rank : 175)
Query Neighborhood Hits	417	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.838896 (rank : 48)	θ value	1.25267e-09 (rank : 174)
Query Neighborhood Hits	417	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

GABP2_HUMAN
NC score	0.838213 (rank : 49)	θ value	1.42992e-13 (rank : 119)
Query Neighborhood Hits	417	Target Neighborhood Hits	454	Shared Neighborhood Hits	292
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP3_MOUSE
NC score	0.836247 (rank : 50)	θ value	6.00763e-12 (rank : 139)
Query Neighborhood Hits	417	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

TRPA1_MOUSE
NC score	0.834584 (rank : 51)	θ value	3.88503e-19 (rank : 45)
Query Neighborhood Hits	417	Target Neighborhood Hits	343	Shared Neighborhood Hits	294
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

MTPN_MOUSE
NC score	0.833785 (rank : 52)	θ value	2.79066e-09 (rank : 186)
Query Neighborhood Hits	417	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

TRPA1_HUMAN
NC score	0.832196 (rank : 53)	θ value	6.20254e-17 (rank : 67)
Query Neighborhood Hits	417	Target Neighborhood Hits	339	Shared Neighborhood Hits	297
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

MTPN_HUMAN
NC score	0.830634 (rank : 54)	θ value	8.11959e-09 (rank : 191)
Query Neighborhood Hits	417	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

BCL3_HUMAN
NC score	0.830572 (rank : 55)	θ value	1.86753e-13 (rank : 123)
Query Neighborhood Hits	417	Target Neighborhood Hits	324	Shared Neighborhood Hits	285
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANKR5_MOUSE
NC score	0.829117 (rank : 56)	θ value	7.58209e-15 (rank : 93)
Query Neighborhood Hits	417	Target Neighborhood Hits	298	Shared Neighborhood Hits	285
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_HUMAN
NC score	0.828965 (rank : 57)	θ value	6.20254e-17 (rank : 66)
Query Neighborhood Hits	417	Target Neighborhood Hits	297	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR7_HUMAN
NC score	0.828192 (rank : 58)	θ value	6.41864e-14 (rank : 105)
Query Neighborhood Hits	417	Target Neighborhood Hits	286	Shared Neighborhood Hits	283
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

BCL3_MOUSE
NC score	0.827393 (rank : 59)	θ value	2.20605e-14 (rank : 97)
Query Neighborhood Hits	417	Target Neighborhood Hits	388	Shared Neighborhood Hits	282
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

RFXK_HUMAN
NC score	0.826255 (rank : 60)	θ value	1.16975e-15 (rank : 84)
Query Neighborhood Hits	417	Target Neighborhood Hits	282	Shared Neighborhood Hits	265
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANKS3_MOUSE
NC score	0.825698 (rank : 61)	θ value	7.84624e-12 (rank : 143)
Query Neighborhood Hits	417	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

PA2G6_MOUSE
NC score	0.824263 (rank : 62)	θ value	8.95645e-16 (rank : 83)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB15_HUMAN
NC score	0.823413 (rank : 63)	θ value	4.74913e-17 (rank : 65)
Query Neighborhood Hits	417	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

CDN2C_HUMAN
NC score	0.823379 (rank : 64)	θ value	1.38499e-08 (rank : 192)
Query Neighborhood Hits	417	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_MOUSE
NC score	0.822816 (rank : 65)	θ value	6.87365e-08 (rank : 203)
Query Neighborhood Hits	417	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKS3_HUMAN
NC score	0.822654 (rank : 66)	θ value	4.59992e-12 (rank : 137)
Query Neighborhood Hits	417	Target Neighborhood Hits	355	Shared Neighborhood Hits	276
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASZ1_MOUSE
NC score	0.821941 (rank : 67)	θ value	1.63604e-09 (rank : 178)
Query Neighborhood Hits	417	Target Neighborhood Hits	319	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANRA2_HUMAN
NC score	0.821460 (rank : 68)	θ value	9.59137e-10 (rank : 171)
Query Neighborhood Hits	417	Target Neighborhood Hits	288	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
NC score	0.820351 (rank : 69)	θ value	1.63604e-09 (rank : 177)
Query Neighborhood Hits	417	Target Neighborhood Hits	287	Shared Neighborhood Hits	278
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASZ1_HUMAN
NC score	0.819284 (rank : 70)	θ value	2.79066e-09 (rank : 183)
Query Neighborhood Hits	417	Target Neighborhood Hits	341	Shared Neighborhood Hits	278
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKS1_HUMAN
NC score	0.818057 (rank : 71)	θ value	2.5182e-18 (rank : 52)
Query Neighborhood Hits	417	Target Neighborhood Hits	438	Shared Neighborhood Hits	304
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

PA2G6_HUMAN
NC score	0.817685 (rank : 72)	θ value	7.09661e-13 (rank : 132)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RFXK_MOUSE
NC score	0.817278 (rank : 73)	θ value	6.41864e-14 (rank : 111)
Query Neighborhood Hits	417	Target Neighborhood Hits	273	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB16_MOUSE
NC score	0.815941 (rank : 74)	θ value	1.74796e-11 (rank : 151)
Query Neighborhood Hits	417	Target Neighborhood Hits	306	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MYPT1_MOUSE
NC score	0.815674 (rank : 75)	θ value	6.41864e-14 (rank : 109)
Query Neighborhood Hits	417	Target Neighborhood Hits	539	Shared Neighborhood Hits	301
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MIB1_HUMAN
NC score	0.814354 (rank : 76)	θ value	1.80466e-16 (rank : 69)
Query Neighborhood Hits	417	Target Neighborhood Hits	470	Shared Neighborhood Hits	298
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

AN36B_HUMAN
NC score	0.813943 (rank : 77)	θ value	4.02038e-16 (rank : 78)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	288
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANKS6_MOUSE
NC score	0.813399 (rank : 78)	θ value	5.62301e-10 (rank : 164)
Query Neighborhood Hits	417	Target Neighborhood Hits	435	Shared Neighborhood Hits	299
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

MIB1_MOUSE
NC score	0.813394 (rank : 79)	θ value	3.07829e-16 (rank : 77)
Query Neighborhood Hits	417	Target Neighborhood Hits	471	Shared Neighborhood Hits	296
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANKS6_HUMAN
NC score	0.813172 (rank : 80)	θ value	1.9326e-10 (rank : 163)
Query Neighborhood Hits	417	Target Neighborhood Hits	411	Shared Neighborhood Hits	298
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB15_MOUSE
NC score	0.812683 (rank : 81)	θ value	5.25075e-16 (rank : 81)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

PP16A_MOUSE
NC score	0.812635 (rank : 82)	θ value	2.98157e-11 (rank : 154)
Query Neighborhood Hits	417	Target Neighborhood Hits	318	Shared Neighborhood Hits	282
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ASB14_MOUSE
NC score	0.812622 (rank : 83)	θ value	5.8054e-15 (rank : 92)
Query Neighborhood Hits	417	Target Neighborhood Hits	293	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

MIB2_HUMAN
NC score	0.811424 (rank : 84)	θ value	1.92812e-18 (rank : 50)
Query Neighborhood Hits	417	Target Neighborhood Hits	438	Shared Neighborhood Hits	288
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
NC score	0.811412 (rank : 85)	θ value	3.88503e-19 (rank : 44)
Query Neighborhood Hits	417	Target Neighborhood Hits	409	Shared Neighborhood Hits	283
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ASB16_HUMAN
NC score	0.811042 (rank : 86)	θ value	7.34386e-10 (rank : 170)
Query Neighborhood Hits	417	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB11_MOUSE
NC score	0.810988 (rank : 87)	θ value	3.18553e-13 (rank : 128)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANR10_MOUSE
NC score	0.810461 (rank : 88)	θ value	1.133e-10 (rank : 161)
Query Neighborhood Hits	417	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR22_HUMAN
NC score	0.810026 (rank : 89)	θ value	7.34386e-10 (rank : 168)
Query Neighborhood Hits	417	Target Neighborhood Hits	243	Shared Neighborhood Hits	241
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB9_HUMAN
NC score	0.809586 (rank : 90)	θ value	1.09485e-13 (rank : 115)
Query Neighborhood Hits	417	Target Neighborhood Hits	267	Shared Neighborhood Hits	258
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB11_HUMAN
NC score	0.809285 (rank : 91)	θ value	6.41864e-14 (rank : 107)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

PP16A_HUMAN
NC score	0.809087 (rank : 92)	θ value	3.40345e-15 (rank : 91)
Query Neighborhood Hits	417	Target Neighborhood Hits	340	Shared Neighborhood Hits	276
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR10_HUMAN
NC score	0.808859 (rank : 93)	θ value	2.79066e-09 (rank : 182)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

CDN2D_HUMAN
NC score	0.808201 (rank : 94)	θ value	3.41135e-07 (rank : 210)
Query Neighborhood Hits	417	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB5_HUMAN
NC score	0.808164 (rank : 95)	θ value	3.76295e-14 (rank : 101)
Query Neighborhood Hits	417	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
NC score	0.805230 (rank : 96)	θ value	8.38298e-14 (rank : 112)
Query Neighborhood Hits	417	Target Neighborhood Hits	266	Shared Neighborhood Hits	260
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

PP16B_HUMAN
NC score	0.803924 (rank : 97)	θ value	7.84624e-12 (rank : 145)
Query Neighborhood Hits	417	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PP16B_MOUSE
NC score	0.803103 (rank : 98)	θ value	2.28291e-11 (rank : 153)
Query Neighborhood Hits	417	Target Neighborhood Hits	302	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANKS1_MOUSE
NC score	0.802968 (rank : 99)	θ value	1.52774e-15 (rank : 85)
Query Neighborhood Hits	417	Target Neighborhood Hits	453	Shared Neighborhood Hits	299
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ASB9_MOUSE
NC score	0.801308 (rank : 100)	θ value	2.0648e-12 (rank : 135)
Query Neighborhood Hits	417	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CDN2D_MOUSE
NC score	0.798783 (rank : 101)	θ value	1.29631e-06 (rank : 220)
Query Neighborhood Hits	417	Target Neighborhood Hits	267	Shared Neighborhood Hits	266
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

MYPT2_HUMAN
NC score	0.798288 (rank : 102)	θ value	2.20605e-14 (rank : 98)
Query Neighborhood Hits	417	Target Neighborhood Hits	707	Shared Neighborhood Hits	301
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

CSKI2_HUMAN
NC score	0.797949 (rank : 103)	θ value	2.35696e-16 (rank : 73)
Query Neighborhood Hits	417	Target Neighborhood Hits	747	Shared Neighborhood Hits	312
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MYPT1_HUMAN
NC score	0.797576 (rank : 104)	θ value	6.41864e-14 (rank : 108)
Query Neighborhood Hits	417	Target Neighborhood Hits	723	Shared Neighborhood Hits	304
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CSKI2_MOUSE
NC score	0.795875 (rank : 105)	θ value	3.07829e-16 (rank : 76)
Query Neighborhood Hits	417	Target Neighborhood Hits	812	Shared Neighborhood Hits	308
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR46_HUMAN
NC score	0.795783 (rank : 106)	θ value	1.69304e-06 (rank : 223)
Query Neighborhood Hits	417	Target Neighborhood Hits	281	Shared Neighborhood Hits	278
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ACBD6_MOUSE
NC score	0.795693 (rank : 107)	θ value	6.64225e-11 (rank : 158)
Query Neighborhood Hits	417	Target Neighborhood Hits	305	Shared Neighborhood Hits	290
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IKBA_HUMAN
NC score	0.794301 (rank : 108)	θ value	2.79066e-09 (rank : 184)
Query Neighborhood Hits	417	Target Neighborhood Hits	280	Shared Neighborhood Hits	271
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

BARD1_HUMAN
NC score	0.793788 (rank : 109)	θ value	1.09485e-13 (rank : 116)
Query Neighborhood Hits	417	Target Neighborhood Hits	427	Shared Neighborhood Hits	298
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
NC score	0.793707 (rank : 110)	θ value	1.29331e-14 (rank : 95)
Query Neighborhood Hits	417	Target Neighborhood Hits	411	Shared Neighborhood Hits	288
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

RN5A_HUMAN
NC score	0.793616 (rank : 111)	θ value	6.00763e-12 (rank : 141)
Query Neighborhood Hits	417	Target Neighborhood Hits	608	Shared Neighborhood Hits	284
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANK2_HUMAN
NC score	0.792863 (rank : 112)	θ value	1.24688e-25 (rank : 17)
Query Neighborhood Hits	417	Target Neighborhood Hits	1615	Shared Neighborhood Hits	353
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB4_HUMAN
NC score	0.792347 (rank : 113)	θ value	6.21693e-09 (rank : 190)
Query Neighborhood Hits	417	Target Neighborhood Hits	264	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ACBD6_HUMAN
NC score	0.791240 (rank : 114)	θ value	7.84624e-12 (rank : 142)
Query Neighborhood Hits	417	Target Neighborhood Hits	304	Shared Neighborhood Hits	288
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB4_MOUSE
NC score	0.790731 (rank : 115)	θ value	1.80886e-08 (rank : 193)
Query Neighborhood Hits	417	Target Neighborhood Hits	265	Shared Neighborhood Hits	257
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CSKI1_HUMAN
NC score	0.790193 (rank : 116)	θ value	5.60996e-18 (rank : 58)
Query Neighborhood Hits	417	Target Neighborhood Hits	997	Shared Neighborhood Hits	315
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
NC score	0.789598 (rank : 117)	θ value	1.47631e-18 (rank : 49)
Query Neighborhood Hits	417	Target Neighborhood Hits	1031	Shared Neighborhood Hits	312
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR46_MOUSE
NC score	0.789258 (rank : 118)	θ value	8.40245e-06 (rank : 238)
Query Neighborhood Hits	417	Target Neighborhood Hits	274	Shared Neighborhood Hits	271
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB12_HUMAN
NC score	0.787673 (rank : 119)	θ value	6.21693e-09 (rank : 189)
Query Neighborhood Hits	417	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB1_HUMAN
NC score	0.787417 (rank : 120)	θ value	7.59969e-07 (rank : 215)
Query Neighborhood Hits	417	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CT086_HUMAN
NC score	0.787147 (rank : 121)	θ value	0.00020696 (rank : 256)
Query Neighborhood Hits	417	Target Neighborhood Hits	277	Shared Neighborhood Hits	271
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ASB12_MOUSE
NC score	0.786109 (rank : 122)	θ value	7.34386e-10 (rank : 169)
Query Neighborhood Hits	417	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR35_HUMAN
NC score	0.785371 (rank : 123)	θ value	4.74913e-17 (rank : 64)
Query Neighborhood Hits	417	Target Neighborhood Hits	784	Shared Neighborhood Hits	295
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB1_MOUSE
NC score	0.784719 (rank : 124)	θ value	5.81887e-07 (rank : 213)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

IKBE_MOUSE
NC score	0.783359 (rank : 125)	θ value	8.97725e-08 (rank : 205)
Query Neighborhood Hits	417	Target Neighborhood Hits	308	Shared Neighborhood Hits	273
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

IKBA_MOUSE
NC score	0.782984 (rank : 126)	θ value	2.13673e-09 (rank : 180)
Query Neighborhood Hits	417	Target Neighborhood Hits	283	Shared Neighborhood Hits	272
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

POTE8_HUMAN
NC score	0.782018 (rank : 127)	θ value	7.84624e-12 (rank : 144)
Query Neighborhood Hits	417	Target Neighborhood Hits	337	Shared Neighborhood Hits	290
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

AN36A_HUMAN
NC score	0.780326 (rank : 128)	θ value	7.34386e-10 (rank : 167)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	269
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR19_HUMAN
NC score	0.778746 (rank : 129)	θ value	3.89403e-11 (rank : 156)
Query Neighborhood Hits	417	Target Neighborhood Hits	276	Shared Neighborhood Hits	273
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ZDH17_HUMAN
NC score	0.769743 (rank : 130)	θ value	1.37858e-24 (rank : 20)
Query Neighborhood Hits	417	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH17_MOUSE
NC score	0.765377 (rank : 131)	θ value	4.01107e-24 (rank : 22)
Query Neighborhood Hits	417	Target Neighborhood Hits	328	Shared Neighborhood Hits	277
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

USH1G_MOUSE
NC score	0.764352 (rank : 132)	θ value	2.36244e-08 (rank : 198)
Query Neighborhood Hits	417	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.764224 (rank : 133)	θ value	2.36244e-08 (rank : 197)
Query Neighborhood Hits	417	Target Neighborhood Hits	267	Shared Neighborhood Hits	262
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

IKBE_HUMAN
NC score	0.763632 (rank : 134)	θ value	2.79066e-09 (rank : 185)
Query Neighborhood Hits	417	Target Neighborhood Hits	288	Shared Neighborhood Hits	269
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ZDH13_HUMAN
NC score	0.755554 (rank : 135)	θ value	2.35696e-16 (rank : 74)
Query Neighborhood Hits	417	Target Neighborhood Hits	322	Shared Neighborhood Hits	276
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANS4B_HUMAN
NC score	0.755136 (rank : 136)	θ value	3.77169e-06 (rank : 229)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	261
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANKY2_HUMAN
NC score	0.753319 (rank : 137)	θ value	8.67504e-11 (rank : 160)
Query Neighborhood Hits	417	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ZDH13_MOUSE
NC score	0.752975 (rank : 138)	θ value	2.35696e-16 (rank : 75)
Query Neighborhood Hits	417	Target Neighborhood Hits	329	Shared Neighborhood Hits	279
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

RN5A_MOUSE
NC score	0.752047 (rank : 139)	θ value	1.80466e-16 (rank : 72)
Query Neighborhood Hits	417	Target Neighborhood Hits	899	Shared Neighborhood Hits	299
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR32_HUMAN
NC score	0.750895 (rank : 140)	θ value	8.40245e-06 (rank : 237)
Query Neighborhood Hits	417	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANFY1_MOUSE
NC score	0.747716 (rank : 141)	θ value	1.33837e-11 (rank : 148)
Query Neighborhood Hits	417	Target Neighborhood Hits	480	Shared Neighborhood Hits	296
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.745451 (rank : 142)	θ value	3.89403e-11 (rank : 155)
Query Neighborhood Hits	417	Target Neighborhood Hits	480	Shared Neighborhood Hits	286
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANS4B_MOUSE
NC score	0.744740 (rank : 143)	θ value	1.29631e-06 (rank : 218)
Query Neighborhood Hits	417	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR32_MOUSE
NC score	0.742707 (rank : 144)	θ value	1.69304e-06 (rank : 221)
Query Neighborhood Hits	417	Target Neighborhood Hits	285	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBB_MOUSE
NC score	0.735962 (rank : 145)	θ value	0.0563607 (rank : 299)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	274
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR11_HUMAN
NC score	0.735704 (rank : 146)	θ value	6.64225e-11 (rank : 159)
Query Neighborhood Hits	417	Target Neighborhood Hits	1289	Shared Neighborhood Hits	314
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR21_HUMAN
NC score	0.735169 (rank : 147)	θ value	4.91457e-14 (rank : 102)
Query Neighborhood Hits	417	Target Neighborhood Hits	864	Shared Neighborhood Hits	302
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

IKBB_HUMAN
NC score	0.735141 (rank : 148)	θ value	0.0113563 (rank : 279)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

POT15_HUMAN
NC score	0.734764 (rank : 149)	θ value	6.41864e-14 (rank : 110)
Query Neighborhood Hits	417	Target Neighborhood Hits	893	Shared Neighborhood Hits	298
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

CTTB2_HUMAN
NC score	0.734526 (rank : 150)	θ value	3.63628e-17 (rank : 63)
Query Neighborhood Hits	417	Target Neighborhood Hits	1061	Shared Neighborhood Hits	301
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR15_HUMAN
NC score	0.730255 (rank : 151)	θ value	1.2105e-12 (rank : 133)
Query Neighborhood Hits	417	Target Neighborhood Hits	478	Shared Neighborhood Hits	280
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANKY2_MOUSE
NC score	0.725760 (rank : 152)	θ value	2.13673e-09 (rank : 179)
Query Neighborhood Hits	417	Target Neighborhood Hits	316	Shared Neighborhood Hits	266
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR47_MOUSE
NC score	0.721320 (rank : 153)	θ value	3.64472e-09 (rank : 187)
Query Neighborhood Hits	417	Target Neighborhood Hits	350	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR37_HUMAN
NC score	0.718684 (rank : 154)	θ value	3.19293e-05 (rank : 246)
Query Neighborhood Hits	417	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB6_HUMAN
NC score	0.715339 (rank : 155)	θ value	0.0252991 (rank : 289)
Query Neighborhood Hits	417	Target Neighborhood Hits	256	Shared Neighborhood Hits	247
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR41_HUMAN
NC score	0.714330 (rank : 156)	θ value	0.0961366 (rank : 303)
Query Neighborhood Hits	417	Target Neighborhood Hits	332	Shared Neighborhood Hits	254
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

POT14_HUMAN
NC score	0.713458 (rank : 157)	θ value	2.88788e-06 (rank : 228)
Query Neighborhood Hits	417	Target Neighborhood Hits	403	Shared Neighborhood Hits	284
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ASB6_MOUSE
NC score	0.711406 (rank : 158)	θ value	0.00869519 (rank : 275)
Query Neighborhood Hits	417	Target Neighborhood Hits	264	Shared Neighborhood Hits	245
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR12_HUMAN
NC score	0.708949 (rank : 159)	θ value	6.41864e-14 (rank : 106)
Query Neighborhood Hits	417	Target Neighborhood Hits	1081	Shared Neighborhood Hits	304
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR47_HUMAN
NC score	0.706468 (rank : 160)	θ value	1.133e-10 (rank : 162)
Query Neighborhood Hits	417	Target Neighborhood Hits	369	Shared Neighborhood Hits	260
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

SNCAP_HUMAN
NC score	0.703866 (rank : 161)	θ value	9.92553e-07 (rank : 217)
Query Neighborhood Hits	417	Target Neighborhood Hits	313	Shared Neighborhood Hits	239
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SHAN1_HUMAN
NC score	0.703491 (rank : 162)	θ value	1.09485e-13 (rank : 118)
Query Neighborhood Hits	417	Target Neighborhood Hits	1041	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

NFKB1_MOUSE
NC score	0.701533 (rank : 163)	θ value	2.13673e-09 (rank : 181)
Query Neighborhood Hits	417	Target Neighborhood Hits	300	Shared Neighborhood Hits	270
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB2_HUMAN
NC score	0.701328 (rank : 164)	θ value	3.64472e-09 (rank : 188)
Query Neighborhood Hits	417	Target Neighborhood Hits	325	Shared Neighborhood Hits	279
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NFKB1_HUMAN
NC score	0.700958 (rank : 165)	θ value	1.25267e-09 (rank : 176)
Query Neighborhood Hits	417	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR37_MOUSE
NC score	0.699210 (rank : 166)	θ value	5.44631e-05 (rank : 249)
Query Neighborhood Hits	417	Target Neighborhood Hits	237	Shared Neighborhood Hits	236
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

BCOR_MOUSE
NC score	0.698098 (rank : 167)	θ value	3.77169e-06 (rank : 230)
Query Neighborhood Hits	417	Target Neighborhood Hits	521	Shared Neighborhood Hits	284
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CLPB_MOUSE
NC score	0.691115 (rank : 168)	θ value	3.41135e-07 (rank : 211)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	247
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

BCOR_HUMAN
NC score	0.689849 (rank : 169)	θ value	4.92598e-06 (rank : 232)
Query Neighborhood Hits	417	Target Neighborhood Hits	609	Shared Neighborhood Hits	290
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD2A1_MOUSE
NC score	0.688182 (rank : 170)	θ value	1.53129e-07 (rank : 206)
Query Neighborhood Hits	417	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

MPP8_HUMAN
NC score	0.685285 (rank : 171)	θ value	9.59137e-10 (rank : 172)
Query Neighborhood Hits	417	Target Neighborhood Hits	948	Shared Neighborhood Hits	284
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NFKB2_MOUSE
NC score	0.685003 (rank : 172)	θ value	1.80886e-08 (rank : 194)
Query Neighborhood Hits	417	Target Neighborhood Hits	326	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR33_MOUSE
NC score	0.683434 (rank : 173)	θ value	0.00102713 (rank : 265)
Query Neighborhood Hits	417	Target Neighborhood Hits	225	Shared Neighborhood Hits	223
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR25_HUMAN
NC score	0.679497 (rank : 174)	θ value	6.87365e-08 (rank : 202)
Query Neighborhood Hits	417	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR33_HUMAN
NC score	0.678101 (rank : 175)	θ value	4.92598e-06 (rank : 231)
Query Neighborhood Hits	417	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

POT22_HUMAN
NC score	0.677166 (rank : 176)	θ value	4.1701e-05 (rank : 248)
Query Neighborhood Hits	417	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

A20A3_HUMAN
NC score	0.676860 (rank : 177)	θ value	2.43908e-13 (rank : 124)
Query Neighborhood Hits	417	Target Neighborhood Hits	692	Shared Neighborhood Hits	281
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

KRIT1_MOUSE
NC score	0.676129 (rank : 178)	θ value	1.53129e-07 (rank : 207)
Query Neighborhood Hits	417	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

A20A2_HUMAN
NC score	0.675825 (rank : 179)	θ value	1.09485e-13 (rank : 114)
Query Neighborhood Hits	417	Target Neighborhood Hits	716	Shared Neighborhood Hits	283
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.674684 (rank : 180)	θ value	1.09485e-13 (rank : 113)
Query Neighborhood Hits	417	Target Neighborhood Hits	698	Shared Neighborhood Hits	277
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A4_HUMAN
NC score	0.671970 (rank : 181)	θ value	2.43908e-13 (rank : 125)
Query Neighborhood Hits	417	Target Neighborhood Hits	710	Shared Neighborhood Hits	281
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR25_MOUSE
NC score	0.667914 (rank : 182)	θ value	2.21117e-06 (rank : 226)
Query Neighborhood Hits	417	Target Neighborhood Hits	398	Shared Neighborhood Hits	274
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

KRIT1_HUMAN
NC score	0.665203 (rank : 183)	θ value	4.45536e-07 (rank : 212)
Query Neighborhood Hits	417	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR38_HUMAN
NC score	0.659600 (rank : 184)	θ value	7.59969e-07 (rank : 214)
Query Neighborhood Hits	417	Target Neighborhood Hits	443	Shared Neighborhood Hits	243
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSBL1_HUMAN
NC score	0.650906 (rank : 185)	θ value	1.80886e-08 (rank : 195)
Query Neighborhood Hits	417	Target Neighborhood Hits	368	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSTF1_MOUSE
NC score	0.650640 (rank : 186)	θ value	9.59137e-10 (rank : 173)
Query Neighborhood Hits	417	Target Neighborhood Hits	467	Shared Neighborhood Hits	258
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

CDN2B_MOUSE
NC score	0.643770 (rank : 187)	θ value	0.000158464 (rank : 253)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

OSBL1_MOUSE
NC score	0.639633 (rank : 188)	θ value	4.0297e-08 (rank : 201)
Query Neighborhood Hits	417	Target Neighborhood Hits	336	Shared Neighborhood Hits	280
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR38_MOUSE
NC score	0.636816 (rank : 189)	θ value	1.69304e-06 (rank : 222)
Query Neighborhood Hits	417	Target Neighborhood Hits	512	Shared Neighborhood Hits	240
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSTF1_HUMAN
NC score	0.634945 (rank : 190)	θ value	3.08544e-08 (rank : 200)
Query Neighborhood Hits	417	Target Neighborhood Hits	466	Shared Neighborhood Hits	256
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

RAI14_HUMAN
NC score	0.634124 (rank : 191)	θ value	5.07402e-19 (rank : 46)
Query Neighborhood Hits	417	Target Neighborhood Hits	1367	Shared Neighborhood Hits	312
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR18_HUMAN
NC score	0.619563 (rank : 192)	θ value	5.08577e-11 (rank : 157)
Query Neighborhood Hits	417	Target Neighborhood Hits	1106	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CD2A1_HUMAN
NC score	0.610166 (rank : 193)	θ value	0.000786445 (rank : 263)
Query Neighborhood Hits	417	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CDN2B_HUMAN
NC score	0.605789 (rank : 194)	θ value	0.000461057 (rank : 261)
Query Neighborhood Hits	417	Target Neighborhood Hits	196	Shared Neighborhood Hits	195
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR43_HUMAN
NC score	0.604207 (rank : 195)	θ value	0.000461057 (rank : 260)
Query Neighborhood Hits	417	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

RAI14_MOUSE
NC score	0.601898 (rank : 196)	θ value	2.97466e-19 (rank : 42)
Query Neighborhood Hits	417	Target Neighborhood Hits	1505	Shared Neighborhood Hits	315
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CLPB_HUMAN
NC score	0.598729 (rank : 197)	θ value	0.00102713 (rank : 266)
Query Neighborhood Hits	417	Target Neighborhood Hits	265	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR43_MOUSE
NC score	0.597716 (rank : 198)	θ value	0.00134147 (rank : 267)
Query Neighborhood Hits	417	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

AN30A_HUMAN
NC score	0.594227 (rank : 199)	θ value	2.88119e-14 (rank : 99)
Query Neighborhood Hits	417	Target Neighborhood Hits	1119	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

HECD1_HUMAN
NC score	0.588081 (rank : 200)	θ value	2.44474e-05 (rank : 245)
Query Neighborhood Hits	417	Target Neighborhood Hits	371	Shared Neighborhood Hits	270
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR40_HUMAN
NC score	0.587667 (rank : 201)	θ value	0.000461057 (rank : 258)
Query Neighborhood Hits	417	Target Neighborhood Hits	224	Shared Neighborhood Hits	199
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

NUD12_MOUSE
NC score	0.586292 (rank : 202)	θ value	4.92598e-06 (rank : 234)
Query Neighborhood Hits	417	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANR40_MOUSE
NC score	0.585803 (rank : 203)	θ value	0.000461057 (rank : 259)
Query Neighborhood Hits	417	Target Neighborhood Hits	228	Shared Neighborhood Hits	203
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR45_MOUSE
NC score	0.584373 (rank : 204)	θ value	0.0148317 (rank : 282)
Query Neighborhood Hits	417	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ABTB2_HUMAN
NC score	0.576989 (rank : 205)	θ value	2.44474e-05 (rank : 243)
Query Neighborhood Hits	417	Target Neighborhood Hits	391	Shared Neighborhood Hits	241
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
NC score	0.565628 (rank : 206)	θ value	2.44474e-05 (rank : 244)
Query Neighborhood Hits	417	Target Neighborhood Hits	414	Shared Neighborhood Hits	240
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
NC score	0.561932 (rank : 207)	θ value	3.08544e-08 (rank : 199)
Query Neighborhood Hits	417	Target Neighborhood Hits	1156	Shared Neighborhood Hits	285
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANKK1_HUMAN
NC score	0.553480 (rank : 208)	θ value	2.77775e-25 (rank : 18)
Query Neighborhood Hits	417	Target Neighborhood Hits	1075	Shared Neighborhood Hits	299
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

NUD12_HUMAN
NC score	0.553460 (rank : 209)	θ value	1.43324e-05 (rank : 241)
Query Neighborhood Hits	417	Target Neighborhood Hits	222	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASB14_HUMAN
NC score	0.551525 (rank : 210)	θ value	2.61198e-07 (rank : 209)
Query Neighborhood Hits	417	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

IASPP_HUMAN
NC score	0.549248 (rank : 211)	θ value	0.00020696 (rank : 257)
Query Neighborhood Hits	417	Target Neighborhood Hits	688	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANR45_HUMAN
NC score	0.548840 (rank : 212)	θ value	0.0193708 (rank : 288)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

RIPK4_HUMAN
NC score	0.544650 (rank : 213)	θ value	7.56453e-23 (rank : 31)
Query Neighborhood Hits	417	Target Neighborhood Hits	1094	Shared Neighborhood Hits	303
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

CENB1_HUMAN
NC score	0.544209 (rank : 214)	θ value	7.59969e-07 (rank : 216)
Query Neighborhood Hits	417	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB5_HUMAN
NC score	0.543904 (rank : 215)	θ value	3.19293e-05 (rank : 247)
Query Neighborhood Hits	417	Target Neighborhood Hits	395	Shared Neighborhood Hits	263
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ASPP1_HUMAN
NC score	0.541307 (rank : 216)	θ value	1.09739e-05 (rank : 239)
Query Neighborhood Hits	417	Target Neighborhood Hits	956	Shared Neighborhood Hits	274
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENB2_HUMAN
NC score	0.538788 (rank : 217)	θ value	2.36244e-08 (rank : 196)
Query Neighborhood Hits	417	Target Neighborhood Hits	425	Shared Neighborhood Hits	251
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

TRPV6_MOUSE
NC score	0.537869 (rank : 218)	θ value	1.69304e-06 (rank : 225)
Query Neighborhood Hits	417	Target Neighborhood Hits	284	Shared Neighborhood Hits	258
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANKK1_MOUSE
NC score	0.537452 (rank : 219)	θ value	6.84181e-24 (rank : 23)
Query Neighborhood Hits	417	Target Neighborhood Hits	1072	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

GLSL_HUMAN
NC score	0.530257 (rank : 220)	θ value	4.92598e-06 (rank : 233)
Query Neighborhood Hits	417	Target Neighborhood Hits	211	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ASPP1_MOUSE
NC score	0.529651 (rank : 221)	θ value	1.29631e-06 (rank : 219)
Query Neighborhood Hits	417	Target Neighborhood Hits	1244	Shared Neighborhood Hits	281
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ANKY1_HUMAN
NC score	0.527378 (rank : 222)	θ value	0.0431538 (rank : 296)
Query Neighborhood Hits	417	Target Neighborhood Hits	248	Shared Neighborhood Hits	205
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ILK2_HUMAN
NC score	0.523797 (rank : 223)	θ value	4.91457e-14 (rank : 104)
Query Neighborhood Hits	417	Target Neighborhood Hits	848	Shared Neighborhood Hits	284
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

GLSL_MOUSE
NC score	0.516462 (rank : 224)	θ value	6.43352e-06 (rank : 236)
Query Neighborhood Hits	417	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13B_MOUSE
NC score	0.510352 (rank : 225)	θ value	0.000121331 (rank : 252)
Query Neighborhood Hits	417	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

GIT2_MOUSE
NC score	0.510009 (rank : 226)	θ value	2.88788e-06 (rank : 227)
Query Neighborhood Hits	417	Target Neighborhood Hits	323	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

AN13B_HUMAN
NC score	0.509773 (rank : 227)	θ value	0.000121331 (rank : 251)
Query Neighborhood Hits	417	Target Neighborhood Hits	265	Shared Neighborhood Hits	252
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ILK1_HUMAN
NC score	0.505925 (rank : 228)	θ value	4.91457e-14 (rank : 103)
Query Neighborhood Hits	417	Target Neighborhood Hits	857	Shared Neighborhood Hits	284
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.504387 (rank : 229)	θ value	1.09485e-13 (rank : 117)
Query Neighborhood Hits	417	Target Neighborhood Hits	858	Shared Neighborhood Hits	284
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

UACA_HUMAN
NC score	0.501416 (rank : 230)	θ value	6.20254e-17 (rank : 68)
Query Neighborhood Hits	417	Target Neighborhood Hits	1622	Shared Neighborhood Hits	302
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

IASPP_MOUSE
NC score	0.500823 (rank : 231)	θ value	0.00390308 (rank : 272)
Query Neighborhood Hits	417	Target Neighborhood Hits	1024	Shared Neighborhood Hits	274
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

AN13C_HUMAN
NC score	0.497556 (rank : 232)	θ value	0.0193708 (rank : 287)
Query Neighborhood Hits	417	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT1_MOUSE
NC score	0.491234 (rank : 233)	θ value	7.1131e-05 (rank : 250)
Query Neighborhood Hits	417	Target Neighborhood Hits	341	Shared Neighborhood Hits	246
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.490662 (rank : 234)	θ value	1.87187e-05 (rank : 242)
Query Neighborhood Hits	417	Target Neighborhood Hits	336	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

AN13C_MOUSE
NC score	0.485964 (rank : 235)	θ value	0.0563607 (rank : 298)
Query Neighborhood Hits	417	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

TRPV5_MOUSE
NC score	0.482366 (rank : 236)	θ value	0.0252991 (rank : 291)
Query Neighborhood Hits	417	Target Neighborhood Hits	278	Shared Neighborhood Hits	251
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

GLSK_HUMAN
NC score	0.481123 (rank : 237)	θ value	0.000158464 (rank : 254)
Query Neighborhood Hits	417	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

UACA_MOUSE
NC score	0.475399 (rank : 238)	θ value	4.02038e-16 (rank : 80)
Query Neighborhood Hits	417	Target Neighborhood Hits	1620	Shared Neighborhood Hits	297
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GIT2_HUMAN
NC score	0.472606 (rank : 239)	θ value	1.09739e-05 (rank : 240)
Query Neighborhood Hits	417	Target Neighborhood Hits	381	Shared Neighborhood Hits	246
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ANR26_MOUSE
NC score	0.462333 (rank : 240)	θ value	6.00763e-12 (rank : 138)
Query Neighborhood Hits	417	Target Neighborhood Hits	1554	Shared Neighborhood Hits	302
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC4_MOUSE
NC score	0.459016 (rank : 241)	θ value	1.80466e-16 (rank : 70)
Query Neighborhood Hits	417	Target Neighborhood Hits	872	Shared Neighborhood Hits	288
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CT012_MOUSE
NC score	0.458410 (rank : 242)	θ value	0.00869519 (rank : 276)
Query Neighborhood Hits	417	Target Neighborhood Hits	229	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DDFL1_MOUSE
NC score	0.456549 (rank : 243)	θ value	0.000786445 (rank : 264)
Query Neighborhood Hits	417	Target Neighborhood Hits	324	Shared Neighborhood Hits	250
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

TRPV5_HUMAN
NC score	0.454407 (rank : 244)	θ value	0.0113563 (rank : 280)
Query Neighborhood Hits	417	Target Neighborhood Hits	261	Shared Neighborhood Hits	230
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
NC score	0.453767 (rank : 245)	θ value	0.00298849 (rank : 271)
Query Neighborhood Hits	417	Target Neighborhood Hits	262	Shared Neighborhood Hits	231
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

NOTC4_HUMAN
NC score	0.453652 (rank : 246)	θ value	6.85773e-16 (rank : 82)
Query Neighborhood Hits	417	Target Neighborhood Hits	905	Shared Neighborhood Hits	290
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR26_HUMAN
NC score	0.445270 (rank : 247)	θ value	1.33837e-11 (rank : 149)
Query Neighborhood Hits	417	Target Neighborhood Hits	1614	Shared Neighborhood Hits	311
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_HUMAN
NC score	0.441868 (rank : 248)	θ value	0.21417 (rank : 310)
Query Neighborhood Hits	417	Target Neighborhood Hits	243	Shared Neighborhood Hits	227
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

TNI3K_HUMAN
NC score	0.434821 (rank : 249)	θ value	9.87957e-23 (rank : 33)
Query Neighborhood Hits	417	Target Neighborhood Hits	1084	Shared Neighborhood Hits	300
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.427459 (rank : 250)	θ value	4.29542e-18 (rank : 56)
Query Neighborhood Hits	417	Target Neighborhood Hits	1079	Shared Neighborhood Hits	298
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_HUMAN
NC score	0.422263 (rank : 251)	θ value	0.00665767 (rank : 274)
Query Neighborhood Hits	417	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

SUV91_HUMAN
NC score	0.413455 (rank : 252)	θ value	1.08726e-37 (rank : 5)
Query Neighborhood Hits	417	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

NOTC3_MOUSE
NC score	0.413354 (rank : 253)	θ value	1.02475e-11 (rank : 147)
Query Neighborhood Hits	417	Target Neighborhood Hits	975	Shared Neighborhood Hits	292
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

AN13A_MOUSE
NC score	0.412160 (rank : 254)	θ value	1.81305 (rank : 350)
Query Neighborhood Hits	417	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

NOTC2_HUMAN
NC score	0.411182 (rank : 255)	θ value	6.00763e-12 (rank : 140)
Query Neighborhood Hits	417	Target Neighborhood Hits	1113	Shared Neighborhood Hits	299
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
NC score	0.411181 (rank : 256)	θ value	1.02475e-11 (rank : 146)
Query Neighborhood Hits	417	Target Neighborhood Hits	1062	Shared Neighborhood Hits	295
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.410302 (rank : 257)	θ value	1.2105e-12 (rank : 134)
Query Neighborhood Hits	417	Target Neighborhood Hits	906	Shared Neighborhood Hits	289
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SUV91_MOUSE
NC score	0.410262 (rank : 258)	θ value	3.73686e-38 (rank : 4)
Query Neighborhood Hits	417	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.408810 (rank : 259)	θ value	3.4976e-36 (rank : 6)
Query Neighborhood Hits	417	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

NOTC2_MOUSE
NC score	0.407860 (rank : 260)	θ value	1.74796e-11 (rank : 152)
Query Neighborhood Hits	417	Target Neighborhood Hits	1069	Shared Neighborhood Hits	297
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SUV92_MOUSE
NC score	0.406699 (rank : 261)	θ value	7.79185e-36 (rank : 7)
Query Neighborhood Hits	417	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

DAPK1_MOUSE
NC score	0.393820 (rank : 262)	θ value	4.01107e-24 (rank : 21)
Query Neighborhood Hits	417	Target Neighborhood Hits	1138	Shared Neighborhood Hits	299
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
NC score	0.384952 (rank : 263)	θ value	9.87957e-23 (rank : 32)
Query Neighborhood Hits	417	Target Neighborhood Hits	1130	Shared Neighborhood Hits	294
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_MOUSE
NC score	0.384276 (rank : 264)	θ value	0.000158464 (rank : 255)
Query Neighborhood Hits	417	Target Neighborhood Hits	1333	Shared Neighborhood Hits	272
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDEF2_HUMAN
NC score	0.384047 (rank : 265)	θ value	0.00869519 (rank : 277)
Query Neighborhood Hits	417	Target Neighborhood Hits	599	Shared Neighborhood Hits	234
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.381033 (rank : 266)	θ value	0.0148317 (rank : 283)
Query Neighborhood Hits	417	Target Neighborhood Hits	625	Shared Neighborhood Hits	241
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TEX14_HUMAN
NC score	0.377800 (rank : 267)	θ value	0.0148317 (rank : 286)
Query Neighborhood Hits	417	Target Neighborhood Hits	1103	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDFL1_HUMAN
NC score	0.374655 (rank : 268)	θ value	1.99992e-07 (rank : 208)
Query Neighborhood Hits	417	Target Neighborhood Hits	353	Shared Neighborhood Hits	230
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_HUMAN
NC score	0.373029 (rank : 269)	θ value	0.00509761 (rank : 273)
Query Neighborhood Hits	417	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

SETB2_HUMAN
NC score	0.359776 (rank : 270)	θ value	1.92812e-18 (rank : 51)
Query Neighborhood Hits	417	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

DGKZ_MOUSE
NC score	0.354632 (rank : 271)	θ value	0.00175202 (rank : 268)
Query Neighborhood Hits	417	Target Neighborhood Hits	542	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

SETB1_MOUSE
NC score	0.352339 (rank : 272)	θ value	1.16704e-23 (rank : 26)
Query Neighborhood Hits	417	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

NOTC1_MOUSE
NC score	0.350379 (rank : 273)	θ value	6.87365e-08 (rank : 204)
Query Neighborhood Hits	417	Target Neighborhood Hits	916	Shared Neighborhood Hits	270
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CENG1_MOUSE
NC score	0.348793 (rank : 274)	θ value	0.00298849 (rank : 270)
Query Neighborhood Hits	417	Target Neighborhood Hits	531	Shared Neighborhood Hits	243
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

SETB1_HUMAN
NC score	0.348462 (rank : 275)	θ value	1.16704e-23 (rank : 25)
Query Neighborhood Hits	417	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

CENG1_HUMAN
NC score	0.346422 (rank : 276)	θ value	0.0113563 (rank : 278)
Query Neighborhood Hits	417	Target Neighborhood Hits	544	Shared Neighborhood Hits	243
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_HUMAN
NC score	0.340853 (rank : 277)	θ value	0.47712 (rank : 318)
Query Neighborhood Hits	417	Target Neighborhood Hits	471	Shared Neighborhood Hits	253
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

SETD2_HUMAN
NC score	0.339155 (rank : 278)	θ value	7.0802e-21 (rank : 39)
Query Neighborhood Hits	417	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CENG2_MOUSE
NC score	0.338347 (rank : 279)	θ value	0.62314 (rank : 323)
Query Neighborhood Hits	417	Target Neighborhood Hits	463	Shared Neighborhood Hits	250
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DGKI_HUMAN
NC score	0.337588 (rank : 280)	θ value	0.0148317 (rank : 284)
Query Neighborhood Hits	417	Target Neighborhood Hits	609	Shared Neighborhood Hits	214
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

EZH1_HUMAN
NC score	0.334046 (rank : 281)	θ value	2.7842e-17 (rank : 62)
Query Neighborhood Hits	417	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
NC score	0.333982 (rank : 282)	θ value	2.60593e-15 (rank : 87)
Query Neighborhood Hits	417	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_MOUSE
NC score	0.333651 (rank : 283)	θ value	1.24977e-17 (rank : 60)
Query Neighborhood Hits	417	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_MOUSE
NC score	0.330878 (rank : 284)	θ value	1.29331e-14 (rank : 96)
Query Neighborhood Hits	417	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

IKBL_HUMAN
NC score	0.327248 (rank : 285)	θ value	0.62314 (rank : 324)
Query Neighborhood Hits	417	Target Neighborhood Hits	168	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.322288 (rank : 286)	θ value	0.62314 (rank : 325)
Query Neighborhood Hits	417	Target Neighborhood Hits	196	Shared Neighborhood Hits	143
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ABTB1_MOUSE
NC score	0.320593 (rank : 287)	θ value	0.0148317 (rank : 281)
Query Neighborhood Hits	417	Target Neighborhood Hits	349	Shared Neighborhood Hits	177
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ANKZ1_MOUSE
NC score	0.310500 (rank : 288)	θ value	3.0926 (rank : 363)
Query Neighborhood Hits	417	Target Neighborhood Hits	208	Shared Neighborhood Hits	152
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CENG3_MOUSE
NC score	0.307305 (rank : 289)	θ value	1.81305 (rank : 352)
Query Neighborhood Hits	417	Target Neighborhood Hits	467	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.307147 (rank : 290)	θ value	1.81305 (rank : 351)
Query Neighborhood Hits	417	Target Neighborhood Hits	455	Shared Neighborhood Hits	227
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

SET1A_HUMAN
NC score	0.295964 (rank : 291)	θ value	1.33837e-11 (rank : 150)
Query Neighborhood Hits	417	Target Neighborhood Hits	690	Shared Neighborhood Hits	71
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CLR59_HUMAN
NC score	0.290559 (rank : 292)	θ value	0.0252991 (rank : 290)
Query Neighborhood Hits	417	Target Neighborhood Hits	163	Shared Neighborhood Hits	137
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

DDEF1_MOUSE
NC score	0.286979 (rank : 293)	θ value	0.365318 (rank : 315)
Query Neighborhood Hits	417	Target Neighborhood Hits	592	Shared Neighborhood Hits	194
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ANKZ1_HUMAN
NC score	0.283683 (rank : 294)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	417	Target Neighborhood Hits	236	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

NSD1_MOUSE
NC score	0.282136 (rank : 295)	θ value	4.02038e-16 (rank : 79)
Query Neighborhood Hits	417	Target Neighborhood Hits	472	Shared Neighborhood Hits	45
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SETD8_MOUSE
NC score	0.281491 (rank : 296)	θ value	1.69304e-06 (rank : 224)
Query Neighborhood Hits	417	Target Neighborhood Hits	131	Shared Neighborhood Hits	28
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
NC score	0.278975 (rank : 297)	θ value	4.92598e-06 (rank : 235)
Query Neighborhood Hits	417	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

NSD1_HUMAN
NC score	0.278940 (rank : 298)	θ value	1.80466e-16 (rank : 71)
Query Neighborhood Hits	417	Target Neighborhood Hits	427	Shared Neighborhood Hits	48
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ABTB1_HUMAN
NC score	0.278491 (rank : 299)	θ value	0.0431538 (rank : 295)
Query Neighborhood Hits	417	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

BAT4_MOUSE
NC score	0.266932 (rank : 300)	θ value	1.38821 (rank : 338)
Query Neighborhood Hits	417	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

HRX_HUMAN
NC score	0.266641 (rank : 301)	θ value	2.88119e-14 (rank : 100)
Query Neighborhood Hits	417	Target Neighborhood Hits	825	Shared Neighborhood Hits	63
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ANKR9_MOUSE
NC score	0.264148 (rank : 302)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	417	Target Neighborhood Hits	120	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

MLL4_HUMAN
NC score	0.253591 (rank : 303)	θ value	7.09661e-13 (rank : 131)
Query Neighborhood Hits	417	Target Neighborhood Hits	722	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TRPV3_HUMAN
NC score	0.240205 (rank : 304)	θ value	0.00175202 (rank : 269)
Query Neighborhood Hits	417	Target Neighborhood Hits	198	Shared Neighborhood Hits	148
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.239718 (rank : 305)	θ value	0.000602161 (rank : 262)
Query Neighborhood Hits	417	Target Neighborhood Hits	188	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_MOUSE
NC score	0.234377 (rank : 306)	θ value	1.38821 (rank : 348)
Query Neighborhood Hits	417	Target Neighborhood Hits	189	Shared Neighborhood Hits	161
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

BAT4_HUMAN
NC score	0.226099 (rank : 307)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	417	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

RSNL2_HUMAN
NC score	0.222828 (rank : 308)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	417	Target Neighborhood Hits	136	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV1_HUMAN
NC score	0.221476 (rank : 309)	θ value	2.36792 (rank : 362)
Query Neighborhood Hits	417	Target Neighborhood Hits	184	Shared Neighborhood Hits	153
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

ANKR9_HUMAN
NC score	0.215732 (rank : 310)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	417	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

MLL3_MOUSE
NC score	0.211349 (rank : 311)	θ value	2.43908e-13 (rank : 126)
Query Neighborhood Hits	417	Target Neighborhood Hits	1399	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.205335 (rank : 312)	θ value	1.42992e-13 (rank : 121)
Query Neighborhood Hits	417	Target Neighborhood Hits	1644	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL2_HUMAN
NC score	0.204687 (rank : 313)	θ value	7.09661e-13 (rank : 130)
Query Neighborhood Hits	417	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TRPV2_HUMAN
NC score	0.200413 (rank : 314)	θ value	1.06291 (rank : 336)
Query Neighborhood Hits	417	Target Neighborhood Hits	130	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CMTA1_HUMAN
NC score	0.200063 (rank : 315)	θ value	0.0330416 (rank : 292)
Query Neighborhood Hits	417	Target Neighborhood Hits	217	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RSNL2_MOUSE
NC score	0.190525 (rank : 316)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	417	Target Neighborhood Hits	129	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CMTA2_HUMAN
NC score	0.155055 (rank : 317)	θ value	4.03905 (rank : 369)
Query Neighborhood Hits	417	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV2_MOUSE
NC score	0.152163 (rank : 318)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	417	Target Neighborhood Hits	111	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CMTA2_MOUSE
NC score	0.143129 (rank : 319)	θ value	3.0926 (rank : 364)
Query Neighborhood Hits	417	Target Neighborhood Hits	216	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPC6_HUMAN
NC score	0.136384 (rank : 320)	θ value	0.0736092 (rank : 302)
Query Neighborhood Hits	417	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

ANKF1_HUMAN
NC score	0.126428 (rank : 321)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	417	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

TRPV4_HUMAN
NC score	0.123506 (rank : 322)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	417	Target Neighborhood Hits	150	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CU081_HUMAN
NC score	0.120029 (rank : 323)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	417	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

TRPC3_HUMAN
NC score	0.117596 (rank : 324)	θ value	0.0961366 (rank : 307)
Query Neighborhood Hits	417	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPV4_MOUSE
NC score	0.110205 (rank : 325)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	417	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC3_MOUSE
NC score	0.108713 (rank : 326)	θ value	0.365318 (rank : 317)
Query Neighborhood Hits	417	Target Neighborhood Hits	131	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_MOUSE
NC score	0.108362 (rank : 327)	θ value	0.813845 (rank : 331)
Query Neighborhood Hits	417	Target Neighborhood Hits	171	Shared Neighborhood Hits	95
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_MOUSE
NC score	0.102073 (rank : 328)	θ value	0.0961366 (rank : 308)
Query Neighborhood Hits	417	Target Neighborhood Hits	114	Shared Neighborhood Hits	79
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.101458 (rank : 329)	θ value	0.21417 (rank : 313)
Query Neighborhood Hits	417	Target Neighborhood Hits	123	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC5_MOUSE
NC score	0.093176 (rank : 330)	θ value	1.38821 (rank : 347)
Query Neighborhood Hits	417	Target Neighborhood Hits	124	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC4_MOUSE
NC score	0.092780 (rank : 331)	θ value	0.21417 (rank : 312)
Query Neighborhood Hits	417	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.092753 (rank : 332)	θ value	0.21417 (rank : 311)
Query Neighborhood Hits	417	Target Neighborhood Hits	140	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC5_HUMAN
NC score	0.091922 (rank : 333)	θ value	1.38821 (rank : 346)
Query Neighborhood Hits	417	Target Neighborhood Hits	122	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

LRRK1_MOUSE
NC score	0.084318 (rank : 334)	θ value	0.0148317 (rank : 285)
Query Neighborhood Hits	417	Target Neighborhood Hits	1267	Shared Neighborhood Hits	127
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TRPC1_HUMAN
NC score	0.076184 (rank : 335)	θ value	0.0563607 (rank : 301)
Query Neighborhood Hits	417	Target Neighborhood Hits	91	Shared Neighborhood Hits	57
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
NC score	0.070890 (rank : 336)	θ value	0.0961366 (rank : 306)
Query Neighborhood Hits	417	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

LRRK1_HUMAN
NC score	0.058258 (rank : 337)	θ value	5.27518 (rank : 383)
Query Neighborhood Hits	417	Target Neighborhood Hits	1237	Shared Neighborhood Hits	100
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TRDN_HUMAN
NC score	0.057668 (rank : 338)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	417	Target Neighborhood Hits	542	Shared Neighborhood Hits	45
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

LCE1D_HUMAN
NC score	0.055092 (rank : 339)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	417	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

SMP1L_MOUSE
NC score	0.054040 (rank : 340)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	417	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

MUC13_MOUSE
NC score	0.052602 (rank : 341)	θ value	0.0330416 (rank : 293)
Query Neighborhood Hits	417	Target Neighborhood Hits	447	Shared Neighborhood Hits	24
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

LCE1C_HUMAN
NC score	0.052596 (rank : 342)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	417	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

SRRM1_MOUSE
NC score	0.052572 (rank : 343)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	417	Target Neighborhood Hits	966	Shared Neighborhood Hits	60
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SMAP1_MOUSE
NC score	0.052534 (rank : 344)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	417	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

IWS1_MOUSE
NC score	0.052186 (rank : 345)	θ value	5.27518 (rank : 381)
Query Neighborhood Hits	417	Target Neighborhood Hits	1258	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SMP1L_HUMAN
NC score	0.051344 (rank : 346)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	417	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

CENA1_HUMAN
NC score	0.051259 (rank : 347)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	417	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

MDC1_HUMAN
NC score	0.050217 (rank : 348)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	417	Target Neighborhood Hits	1446	Shared Neighborhood Hits	77
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SMAP1_HUMAN
NC score	0.050111 (rank : 349)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	417	Target Neighborhood Hits	98	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

AKA12_HUMAN
NC score	0.048774 (rank : 350)	θ value	1.06291 (rank : 332)
Query Neighborhood Hits	417	Target Neighborhood Hits	825	Shared Neighborhood Hits	54
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DMP1_HUMAN
NC score	0.047044 (rank : 351)	θ value	1.06291 (rank : 333)
Query Neighborhood Hits	417	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

LEO1_MOUSE
NC score	0.041939 (rank : 352)	θ value	0.0961366 (rank : 305)
Query Neighborhood Hits	417	Target Neighborhood Hits	946	Shared Neighborhood Hits	58
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DSPP_MOUSE
NC score	0.040967 (rank : 353)	θ value	0.0961366 (rank : 304)
Query Neighborhood Hits	417	Target Neighborhood Hits	491	Shared Neighborhood Hits	42
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ACINU_HUMAN
NC score	0.040921 (rank : 354)	θ value	0.0563607 (rank : 297)
Query Neighborhood Hits	417	Target Neighborhood Hits	828	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PRR12_HUMAN
NC score	0.040451 (rank : 355)	θ value	0.47712 (rank : 322)
Query Neighborhood Hits	417	Target Neighborhood Hits	460	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

DSPP_HUMAN
NC score	0.038072 (rank : 356)	θ value	0.47712 (rank : 320)
Query Neighborhood Hits	417	Target Neighborhood Hits	645	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_HUMAN
NC score	0.038020 (rank : 357)	θ value	1.38821 (rank : 342)
Query Neighborhood Hits	417	Target Neighborhood Hits	958	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MDN1_HUMAN
NC score	0.036108 (rank : 358)	θ value	5.27518 (rank : 384)
Query Neighborhood Hits	417	Target Neighborhood Hits	662	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

TCAL5_HUMAN
NC score	0.034735 (rank : 359)	θ value	0.279714 (rank : 314)
Query Neighborhood Hits	417	Target Neighborhood Hits	806	Shared Neighborhood Hits	44
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

NSBP1_MOUSE
NC score	0.034290 (rank : 360)	θ value	0.365318 (rank : 316)
Query Neighborhood Hits	417	Target Neighborhood Hits	681	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RIF1_MOUSE
NC score	0.033511 (rank : 361)	θ value	0.0330416 (rank : 294)
Query Neighborhood Hits	417	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SASH1_MOUSE
NC score	0.033147 (rank : 362)	θ value	5.27518 (rank : 389)
Query Neighborhood Hits	417	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

VPS72_HUMAN
NC score	0.030792 (rank : 363)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	417	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CLSPN_MOUSE
NC score	0.030306 (rank : 364)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

SMC2_HUMAN
NC score	0.030280 (rank : 365)	θ value	3.0926 (rank : 368)
Query Neighborhood Hits	417	Target Neighborhood Hits	1405	Shared Neighborhood Hits	46
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

MCPH1_MOUSE
NC score	0.030257 (rank : 366)	θ value	1.38821 (rank : 343)
Query Neighborhood Hits	417	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

RRBP1_MOUSE
NC score	0.028804 (rank : 367)	θ value	3.0926 (rank : 367)
Query Neighborhood Hits	417	Target Neighborhood Hits	1650	Shared Neighborhood Hits	74
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TP53B_MOUSE
NC score	0.027659 (rank : 368)	θ value	4.03905 (rank : 375)
Query Neighborhood Hits	417	Target Neighborhood Hits	644	Shared Neighborhood Hits	44
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MINT_MOUSE
NC score	0.027556 (rank : 369)	θ value	1.06291 (rank : 334)
Query Neighborhood Hits	417	Target Neighborhood Hits	1514	Shared Neighborhood Hits	70
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CENPR_MOUSE
NC score	0.026866 (rank : 370)	θ value	0.47712 (rank : 319)
Query Neighborhood Hits	417	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQ82, Q3TLR0, Q3TNR4	Gene names	Itgb3bp, Cenpr, Nrif3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3).

SASH1_HUMAN
NC score	0.026840 (rank : 371)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	417	Target Neighborhood Hits	292	Shared Neighborhood Hits	24
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

PCGF4_HUMAN
NC score	0.026101 (rank : 372)	θ value	0.62314 (rank : 329)
Query Neighborhood Hits	417	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.026058 (rank : 373)	θ value	0.62314 (rank : 330)
Query Neighborhood Hits	417	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

FILA_HUMAN
NC score	0.025390 (rank : 374)	θ value	1.38821 (rank : 341)
Query Neighborhood Hits	417	Target Neighborhood Hits	685	Shared Neighborhood Hits	41
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SPRL1_MOUSE
NC score	0.024555 (rank : 375)	θ value	1.38821 (rank : 345)
Query Neighborhood Hits	417	Target Neighborhood Hits	403	Shared Neighborhood Hits	40
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

NEST_HUMAN
NC score	0.023888 (rank : 376)	θ value	5.27518 (rank : 385)
Query Neighborhood Hits	417	Target Neighborhood Hits	1305	Shared Neighborhood Hits	62
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NTHL1_HUMAN
NC score	0.022858 (rank : 377)	θ value	0.163984 (rank : 309)
Query Neighborhood Hits	417	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

PCGF2_HUMAN
NC score	0.021567 (rank : 378)	θ value	0.62314 (rank : 327)
Query Neighborhood Hits	417	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

JADE2_HUMAN
NC score	0.020956 (rank : 379)	θ value	1.81305 (rank : 354)
Query Neighborhood Hits	417	Target Neighborhood Hits	199	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

PCGF2_MOUSE
NC score	0.020706 (rank : 380)	θ value	0.62314 (rank : 328)
Query Neighborhood Hits	417	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

OSBL8_HUMAN
NC score	0.020468 (rank : 381)	θ value	5.27518 (rank : 386)
Query Neighborhood Hits	417	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

REN3A_HUMAN
NC score	0.020076 (rank : 382)	θ value	5.27518 (rank : 388)
Query Neighborhood Hits	417	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

INP5E_HUMAN
NC score	0.018664 (rank : 383)	θ value	0.0563607 (rank : 300)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

GRIN1_MOUSE
NC score	0.018118 (rank : 384)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	417	Target Neighborhood Hits	337	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SG16_MOUSE
NC score	0.017820 (rank : 385)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	417	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P02815, Q62263	Gene names	Spt1, Spt-1
Domain Architecture	No domain graphic available
Description	16.5 kDa submandibular gland glycoprotein precursor (Salivary protein 1).

VWF_HUMAN
NC score	0.017269 (rank : 386)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	417	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ROCK1_HUMAN
NC score	0.016838 (rank : 387)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	417	Target Neighborhood Hits	2000	Shared Neighborhood Hits	58
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

DCDC2_MOUSE
NC score	0.015814 (rank : 388)	θ value	1.38821 (rank : 340)
Query Neighborhood Hits	417	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

TNC6B_HUMAN
NC score	0.014019 (rank : 389)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	417	Target Neighborhood Hits	256	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TIF1G_MOUSE
NC score	0.013707 (rank : 390)	θ value	5.27518 (rank : 392)
Query Neighborhood Hits	417	Target Neighborhood Hits	498	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SRCA_HUMAN
NC score	0.013632 (rank : 391)	θ value	4.03905 (rank : 373)
Query Neighborhood Hits	417	Target Neighborhood Hits	380	Shared Neighborhood Hits	38
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

MAST4_HUMAN
NC score	0.013619 (rank : 392)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	417	Target Neighborhood Hits	1804	Shared Neighborhood Hits	76
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SMG5_HUMAN
NC score	0.013378 (rank : 393)	θ value	1.06291 (rank : 335)
Query Neighborhood Hits	417	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SDPR_MOUSE
NC score	0.012395 (rank : 394)	θ value	2.36792 (rank : 361)
Query Neighborhood Hits	417	Target Neighborhood Hits	485	Shared Neighborhood Hits	24
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

NALP5_MOUSE
NC score	0.011529 (rank : 395)	θ value	0.62314 (rank : 326)
Query Neighborhood Hits	417	Target Neighborhood Hits	560	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

MYRIP_HUMAN
NC score	0.010916 (rank : 396)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	417	Target Neighborhood Hits	269	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

LIMA1_MOUSE
NC score	0.010799 (rank : 397)	θ value	5.27518 (rank : 382)
Query Neighborhood Hits	417	Target Neighborhood Hits	298	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

EMID2_HUMAN
NC score	0.010387 (rank : 398)	θ value	4.03905 (rank : 370)
Query Neighborhood Hits	417	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

K0427_MOUSE
NC score	0.009725 (rank : 399)	θ value	1.81305 (rank : 355)
Query Neighborhood Hits	417	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

BBS4_HUMAN
NC score	0.008637 (rank : 400)	θ value	2.36792 (rank : 356)
Query Neighborhood Hits	417	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

MYLK_MOUSE
NC score	0.008171 (rank : 401)	θ value	2.36792 (rank : 359)
Query Neighborhood Hits	417	Target Neighborhood Hits	1489	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

SPEF1_HUMAN
NC score	0.007711 (rank : 402)	θ value	5.27518 (rank : 391)
Query Neighborhood Hits	417	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4P9, Q5JX78	Gene names	SPEF1, C20orf28
Domain Architecture
Description	Sperm flagellar protein 1.

TOIP2_HUMAN
NC score	0.007473 (rank : 403)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	417	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

THAP3_HUMAN
NC score	0.006976 (rank : 404)	θ value	4.03905 (rank : 374)
Query Neighborhood Hits	417	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WTV1, Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2, Q9Y3H3	Gene names	THAP3
Domain Architecture
Description	THAP domain-containing protein 3.

DTX2_MOUSE
NC score	0.006704 (rank : 405)	θ value	2.36792 (rank : 358)
Query Neighborhood Hits	417	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

PMS2_HUMAN
NC score	0.006600 (rank : 406)	θ value	4.03905 (rank : 372)
Query Neighborhood Hits	417	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

BNC2_HUMAN
NC score	0.006461 (rank : 407)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	417	Target Neighborhood Hits	439	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

DDX21_MOUSE
NC score	0.006174 (rank : 408)	θ value	2.36792 (rank : 357)
Query Neighborhood Hits	417	Target Neighborhood Hits	350	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

SMOC1_HUMAN
NC score	0.006147 (rank : 409)	θ value	1.38821 (rank : 344)
Query Neighborhood Hits	417	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

OTU7A_MOUSE
NC score	0.005843 (rank : 410)	θ value	5.27518 (rank : 387)
Query Neighborhood Hits	417	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

MYO9B_HUMAN
NC score	0.005811 (rank : 411)	θ value	2.36792 (rank : 360)
Query Neighborhood Hits	417	Target Neighborhood Hits	641	Shared Neighborhood Hits	40
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

BNC2_MOUSE
NC score	0.005508 (rank : 412)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	417	Target Neighborhood Hits	456	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CHD6_HUMAN
NC score	0.005079 (rank : 413)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	417	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CD2L1_HUMAN
NC score	0.004829 (rank : 414)	θ value	1.38821 (rank : 339)
Query Neighborhood Hits	417	Target Neighborhood Hits	1467	Shared Neighborhood Hits	69
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

SC24B_HUMAN
NC score	0.004435 (rank : 415)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	417	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

GSLG1_MOUSE
NC score	0.004383 (rank : 416)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	417	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

HDAC9_HUMAN
NC score	0.004360 (rank : 417)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	417	Target Neighborhood Hits	201	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

COBA2_HUMAN
NC score	0.003749 (rank : 418)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	417	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PDIA3_MOUSE
NC score	0.003159 (rank : 419)	θ value	4.03905 (rank : 371)
Query Neighborhood Hits	417	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

CACB2_HUMAN
NC score	0.003150 (rank : 420)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	417	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

FOG1_MOUSE
NC score	0.002489 (rank : 421)	θ value	0.47712 (rank : 321)
Query Neighborhood Hits	417	Target Neighborhood Hits	1237	Shared Neighborhood Hits	40
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CACB2_MOUSE
NC score	0.002071 (rank : 422)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	417	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

PDIA3_HUMAN
NC score	0.001962 (rank : 423)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	417	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

INADL_MOUSE
NC score	0.001794 (rank : 424)	θ value	3.0926 (rank : 366)
Query Neighborhood Hits	417	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

COBA2_MOUSE
NC score	0.001206 (rank : 425)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	417	Target Neighborhood Hits	501	Shared Neighborhood Hits	21
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

SOX4_MOUSE
NC score	0.001089 (rank : 426)	θ value	5.27518 (rank : 390)
Query Neighborhood Hits	417	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

PAR3L_HUMAN
NC score	0.000088 (rank : 427)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	417	Target Neighborhood Hits	297	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

IL18R_MOUSE
NC score	0.000049 (rank : 428)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	417	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q61098	Gene names	Il18r1
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp).

FOXC2_HUMAN
NC score	-0.000288 (rank : 429)	θ value	3.0926 (rank : 365)
Query Neighborhood Hits	417	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

CAMKV_HUMAN
NC score	-0.000487 (rank : 430)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	417	Target Neighborhood Hits	1084	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

DDX24_HUMAN
NC score	-0.000527 (rank : 431)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	417	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

FOG1_HUMAN
NC score	-0.001725 (rank : 432)	θ value	1.81305 (rank : 353)
Query Neighborhood Hits	417	Target Neighborhood Hits	981	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HMX3_MOUSE
NC score	-0.007768 (rank : 433)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	417	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

ZFY2_MOUSE
NC score	-0.011646 (rank : 434)	θ value	1.06291 (rank : 337)
Query Neighborhood Hits	417	Target Neighborhood Hits	795	Shared Neighborhood Hits	21
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ZXDB_HUMAN
NC score	-0.012830 (rank : 435)	θ value	5.27518 (rank : 393)
Query Neighborhood Hits	417	Target Neighborhood Hits	753	Shared Neighborhood Hits	14
SwissProt Accessions	P98169, Q9UBB3	Gene names	ZXDB
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDB.

ZN524_MOUSE
NC score	-0.013096 (rank : 436)	θ value	1.38821 (rank : 349)
Query Neighborhood Hits	417	Target Neighborhood Hits	712	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0B1, Q9DCQ0	Gene names	Znf524, Zfp524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

5HT7R_MOUSE
NC score	-0.013423 (rank : 437)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	417	Target Neighborhood Hits	823	Shared Neighborhood Hits	2
SwissProt Accessions	P32304	Gene names	Htr7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

ZBT11_HUMAN
NC score	-0.013933 (rank : 438)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	417	Target Neighborhood Hits	873	Shared Neighborhood Hits	16
SwissProt Accessions	O95625	Gene names	ZBTB11
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 11.