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Network neighborhood for query Sequence : OSBL8_HUMAN

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OSBL8_HUMAN
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBL5_HUMAN
θ value	0 (rank : 1)	NC score	0.943744 (rank : 3)
Query Neighborhood Hits	289	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	0 (rank : 2)	NC score	0.951066 (rank : 2)
Query Neighborhood Hits	289	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL8_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL9_HUMAN
θ value	2.84138e-62 (rank : 4)	NC score	0.821218 (rank : 7)
Query Neighborhood Hits	289	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB10_HUMAN
θ value	1.78386e-56 (rank : 5)	NC score	0.844464 (rank : 4)
Query Neighborhood Hits	289	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_HUMAN
θ value	5.73848e-55 (rank : 6)	NC score	0.821889 (rank : 6)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_MOUSE
θ value	2.84797e-54 (rank : 7)	NC score	0.822209 (rank : 5)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL1_HUMAN
θ value	7.29293e-34 (rank : 8)	NC score	0.512865 (rank : 19)
Query Neighborhood Hits	289	Target Neighborhood Hits	368	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	1.24399e-33 (rank : 9)	NC score	0.524838 (rank : 18)
Query Neighborhood Hits	289	Target Neighborhood Hits	336	Shared Neighborhood Hits	31
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL2_HUMAN
θ value	4.42448e-31 (rank : 10)	NC score	0.754176 (rank : 8)
Query Neighborhood Hits	289	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
θ value	2.42779e-29 (rank : 11)	NC score	0.752198 (rank : 9)
Query Neighborhood Hits	289	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP1_HUMAN
θ value	5.42112e-21 (rank : 12)	NC score	0.676234 (rank : 14)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL6_MOUSE
θ value	7.0802e-21 (rank : 13)	NC score	0.673815 (rank : 15)
Query Neighborhood Hits	289	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_HUMAN
θ value	2.06002e-20 (rank : 14)	NC score	0.682206 (rank : 11)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
θ value	2.27762e-19 (rank : 15)	NC score	0.677022 (rank : 12)
Query Neighborhood Hits	289	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL7_HUMAN
θ value	2.97466e-19 (rank : 16)	NC score	0.691884 (rank : 10)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBP2_HUMAN
θ value	8.65492e-19 (rank : 17)	NC score	0.676271 (rank : 13)
Query Neighborhood Hits	289	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	3.28887e-18 (rank : 18)	NC score	0.664424 (rank : 16)
Query Neighborhood Hits	289	Target Neighborhood Hits	150	Shared Neighborhood Hits	36
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL3_HUMAN
θ value	5.60996e-18 (rank : 19)	NC score	0.663665 (rank : 17)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PELP1_HUMAN
θ value	0.000158464 (rank : 20)	NC score	0.098036 (rank : 42)
Query Neighborhood Hits	289	Target Neighborhood Hits	596	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

VEZA_HUMAN
θ value	0.000786445 (rank : 21)	NC score	0.096048 (rank : 43)
Query Neighborhood Hits	289	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

HAP1_MOUSE
θ value	0.00175202 (rank : 22)	NC score	0.063862 (rank : 71)
Query Neighborhood Hits	289	Target Neighborhood Hits	388	Shared Neighborhood Hits	22
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

CYH4_MOUSE
θ value	0.00298849 (rank : 23)	NC score	0.146595 (rank : 26)
Query Neighborhood Hits	289	Target Neighborhood Hits	134	Shared Neighborhood Hits	29
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

ATBF1_HUMAN
θ value	0.00390308 (rank : 24)	NC score	0.019317 (rank : 233)
Query Neighborhood Hits	289	Target Neighborhood Hits	1547	Shared Neighborhood Hits	39
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CYH4_HUMAN
θ value	0.00665767 (rank : 25)	NC score	0.144098 (rank : 27)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

PELP1_MOUSE
θ value	0.00665767 (rank : 26)	NC score	0.081993 (rank : 53)
Query Neighborhood Hits	289	Target Neighborhood Hits	709	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SPRL1_MOUSE
θ value	0.00665767 (rank : 27)	NC score	0.092996 (rank : 44)
Query Neighborhood Hits	289	Target Neighborhood Hits	403	Shared Neighborhood Hits	105
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CYH3_MOUSE
θ value	0.00869519 (rank : 28)	NC score	0.119498 (rank : 30)
Query Neighborhood Hits	289	Target Neighborhood Hits	148	Shared Neighborhood Hits	27
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

AN32B_MOUSE
θ value	0.0113563 (rank : 29)	NC score	0.081612 (rank : 54)
Query Neighborhood Hits	289	Target Neighborhood Hits	236	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

LEO1_MOUSE
θ value	0.0193708 (rank : 30)	NC score	0.158467 (rank : 24)
Query Neighborhood Hits	289	Target Neighborhood Hits	946	Shared Neighborhood Hits	193
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PPIG_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.050299 (rank : 100)
Query Neighborhood Hits	289	Target Neighborhood Hits	670	Shared Neighborhood Hits	94
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

AN32B_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.076077 (rank : 59)
Query Neighborhood Hits	289	Target Neighborhood Hits	243	Shared Neighborhood Hits	27
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

CYH1_HUMAN
θ value	0.0252991 (rank : 33)	NC score	0.107801 (rank : 35)
Query Neighborhood Hits	289	Target Neighborhood Hits	184	Shared Neighborhood Hits	27
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	0.0252991 (rank : 34)	NC score	0.107828 (rank : 34)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

PEG3_MOUSE
θ value	0.0252991 (rank : 35)	NC score	0.021624 (rank : 219)
Query Neighborhood Hits	289	Target Neighborhood Hits	1101	Shared Neighborhood Hits	106
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

CD2L1_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.015928 (rank : 262)
Query Neighborhood Hits	289	Target Neighborhood Hits	1463	Shared Neighborhood Hits	84
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

MYT1L_MOUSE
θ value	0.0330416 (rank : 37)	NC score	0.060651 (rank : 79)
Query Neighborhood Hits	289	Target Neighborhood Hits	461	Shared Neighborhood Hits	49
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

NUCL_MOUSE
θ value	0.0330416 (rank : 38)	NC score	0.041657 (rank : 124)
Query Neighborhood Hits	289	Target Neighborhood Hits	425	Shared Neighborhood Hits	33
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

DMP1_HUMAN
θ value	0.0431538 (rank : 39)	NC score	0.109883 (rank : 33)
Query Neighborhood Hits	289	Target Neighborhood Hits	491	Shared Neighborhood Hits	105
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

NCKX1_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.048992 (rank : 106)
Query Neighborhood Hits	289	Target Neighborhood Hits	223	Shared Neighborhood Hits	31
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

DAXX_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.082309 (rank : 52)
Query Neighborhood Hits	289	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DSPP_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.086053 (rank : 46)
Query Neighborhood Hits	289	Target Neighborhood Hits	645	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HUWE1_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.038170 (rank : 138)
Query Neighborhood Hits	289	Target Neighborhood Hits	443	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.037962 (rank : 139)
Query Neighborhood Hits	289	Target Neighborhood Hits	406	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

AP3B1_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.047363 (rank : 112)
Query Neighborhood Hits	289	Target Neighborhood Hits	302	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CCAR1_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.055221 (rank : 89)
Query Neighborhood Hits	289	Target Neighborhood Hits	414	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CYH3_HUMAN
θ value	0.0961366 (rank : 47)	NC score	0.103986 (rank : 39)
Query Neighborhood Hits	289	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

MYH3_HUMAN
θ value	0.0961366 (rank : 48)	NC score	0.019520 (rank : 230)
Query Neighborhood Hits	289	Target Neighborhood Hits	1660	Shared Neighborhood Hits	89
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NRDC_MOUSE
θ value	0.0961366 (rank : 49)	NC score	0.037794 (rank : 142)
Query Neighborhood Hits	289	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

BAZ2B_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.040972 (rank : 125)
Query Neighborhood Hits	289	Target Neighborhood Hits	803	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

FBXW7_HUMAN
θ value	0.125558 (rank : 51)	NC score	0.013560 (rank : 274)
Query Neighborhood Hits	289	Target Neighborhood Hits	433	Shared Neighborhood Hits	24
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

TCF8_MOUSE
θ value	0.125558 (rank : 52)	NC score	0.013284 (rank : 276)
Query Neighborhood Hits	289	Target Neighborhood Hits	1067	Shared Neighborhood Hits	48
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

DAXX_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.070638 (rank : 63)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DMP1_MOUSE
θ value	0.163984 (rank : 54)	NC score	0.088302 (rank : 45)
Query Neighborhood Hits	289	Target Neighborhood Hits	498	Shared Neighborhood Hits	90
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

HTSF1_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.069447 (rank : 65)
Query Neighborhood Hits	289	Target Neighborhood Hits	425	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

PRDM2_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.016725 (rank : 255)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	39
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

ROCK1_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.011650 (rank : 285)
Query Neighborhood Hits	289	Target Neighborhood Hits	2126	Shared Neighborhood Hits	77
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RPGR1_MOUSE
θ value	0.163984 (rank : 58)	NC score	0.049566 (rank : 103)
Query Neighborhood Hits	289	Target Neighborhood Hits	713	Shared Neighborhood Hits	58
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SMRC1_MOUSE
θ value	0.163984 (rank : 59)	NC score	0.044266 (rank : 118)
Query Neighborhood Hits	289	Target Neighborhood Hits	459	Shared Neighborhood Hits	76
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

UBF1_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.061802 (rank : 77)
Query Neighborhood Hits	289	Target Neighborhood Hits	415	Shared Neighborhood Hits	58
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

AN32A_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.063338 (rank : 72)
Query Neighborhood Hits	289	Target Neighborhood Hits	254	Shared Neighborhood Hits	20
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	0.21417 (rank : 62)	NC score	0.063338 (rank : 73)
Query Neighborhood Hits	289	Target Neighborhood Hits	254	Shared Neighborhood Hits	20
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

ARS2_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.067567 (rank : 66)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

CD2L1_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.013585 (rank : 273)
Query Neighborhood Hits	289	Target Neighborhood Hits	1467	Shared Neighborhood Hits	78
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CHD8_HUMAN
θ value	0.21417 (rank : 65)	NC score	0.019123 (rank : 234)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CYH2_HUMAN
θ value	0.21417 (rank : 66)	NC score	0.102293 (rank : 40)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	0.21417 (rank : 67)	NC score	0.102289 (rank : 41)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

GNAS3_MOUSE
θ value	0.21417 (rank : 68)	NC score	0.066238 (rank : 68)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

HTSF1_HUMAN
θ value	0.21417 (rank : 69)	NC score	0.062751 (rank : 76)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	41
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

WDR43_HUMAN
θ value	0.21417 (rank : 70)	NC score	0.034554 (rank : 160)
Query Neighborhood Hits	289	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

CD2L2_HUMAN
θ value	0.279714 (rank : 71)	NC score	0.013020 (rank : 279)
Query Neighborhood Hits	289	Target Neighborhood Hits	1439	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CENB5_HUMAN
θ value	0.279714 (rank : 72)	NC score	0.043451 (rank : 121)
Query Neighborhood Hits	289	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

G3BP2_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.033859 (rank : 166)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

LEO1_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.151479 (rank : 25)
Query Neighborhood Hits	289	Target Neighborhood Hits	958	Shared Neighborhood Hits	187
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NP1L3_MOUSE
θ value	0.279714 (rank : 75)	NC score	0.036442 (rank : 150)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	34
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

TRI44_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.048240 (rank : 108)
Query Neighborhood Hits	289	Target Neighborhood Hits	393	Shared Neighborhood Hits	38
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.047978 (rank : 110)
Query Neighborhood Hits	289	Target Neighborhood Hits	327	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

URP2_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.046847 (rank : 115)
Query Neighborhood Hits	289	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

EP400_MOUSE
θ value	0.365318 (rank : 79)	NC score	0.020944 (rank : 223)
Query Neighborhood Hits	289	Target Neighborhood Hits	592	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

HES1_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.032443 (rank : 170)
Query Neighborhood Hits	289	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	0.365318 (rank : 81)	NC score	0.032320 (rank : 173)
Query Neighborhood Hits	289	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

IWS1_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.111565 (rank : 32)
Query Neighborhood Hits	289	Target Neighborhood Hits	1241	Shared Neighborhood Hits	172
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYT1_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.055553 (rank : 88)
Query Neighborhood Hits	289	Target Neighborhood Hits	475	Shared Neighborhood Hits	59
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NUCL_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.038462 (rank : 137)
Query Neighborhood Hits	289	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

PININ_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.052963 (rank : 93)
Query Neighborhood Hits	289	Target Neighborhood Hits	777	Shared Neighborhood Hits	71
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

ROCK1_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.008630 (rank : 302)
Query Neighborhood Hits	289	Target Neighborhood Hits	2000	Shared Neighborhood Hits	70
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

S39A6_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.028809 (rank : 185)
Query Neighborhood Hits	289	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q13433, Q8IXR3, Q96HP5	Gene names	SLC39A6, LIV1
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Estrogen-regulated protein LIV-1).

TCF8_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.014675 (rank : 266)
Query Neighborhood Hits	289	Target Neighborhood Hits	1057	Shared Neighborhood Hits	61
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TF7L2_HUMAN
θ value	0.365318 (rank : 89)	NC score	0.024099 (rank : 208)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

UBP35_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.027086 (rank : 194)
Query Neighborhood Hits	289	Target Neighborhood Hits	223	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

CENPB_MOUSE
θ value	0.47712 (rank : 91)	NC score	0.043797 (rank : 120)
Query Neighborhood Hits	289	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CKAP4_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.022807 (rank : 212)
Query Neighborhood Hits	289	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CLSPN_HUMAN
θ value	0.47712 (rank : 93)	NC score	0.048833 (rank : 107)
Query Neighborhood Hits	289	Target Neighborhood Hits	433	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

MYST3_HUMAN
θ value	0.47712 (rank : 94)	NC score	0.039087 (rank : 131)
Query Neighborhood Hits	289	Target Neighborhood Hits	772	Shared Neighborhood Hits	64
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYT1L_HUMAN
θ value	0.47712 (rank : 95)	NC score	0.058486 (rank : 82)
Query Neighborhood Hits	289	Target Neighborhood Hits	471	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NSBP1_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.066079 (rank : 69)
Query Neighborhood Hits	289	Target Neighborhood Hits	251	Shared Neighborhood Hits	37
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

SWP70_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.104388 (rank : 38)
Query Neighborhood Hits	289	Target Neighborhood Hits	973	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	0.47712 (rank : 98)	NC score	0.106172 (rank : 36)
Query Neighborhood Hits	289	Target Neighborhood Hits	1097	Shared Neighborhood Hits	87
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TTBK1_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.012634 (rank : 281)
Query Neighborhood Hits	289	Target Neighborhood Hits	1058	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

BMP2K_MOUSE
θ value	0.62314 (rank : 100)	NC score	0.010080 (rank : 297)
Query Neighborhood Hits	289	Target Neighborhood Hits	874	Shared Neighborhood Hits	27
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CENB1_HUMAN
θ value	0.62314 (rank : 101)	NC score	0.038868 (rank : 133)
Query Neighborhood Hits	289	Target Neighborhood Hits	383	Shared Neighborhood Hits	28
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

GZF1_HUMAN
θ value	0.62314 (rank : 102)	NC score	-0.001313 (rank : 315)
Query Neighborhood Hits	289	Target Neighborhood Hits	854	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H116, Q96N08, Q9BQK9, Q9H117, Q9H6W6	Gene names	GZF1, ZBTB23, ZNF336
Domain Architecture
Description	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336) (Zinc finger and BTB domain-containing protein 23).

MYH9_MOUSE
θ value	0.62314 (rank : 103)	NC score	0.020991 (rank : 221)
Query Neighborhood Hits	289	Target Neighborhood Hits	1829	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYST3_MOUSE
θ value	0.62314 (rank : 104)	NC score	0.049214 (rank : 105)
Query Neighborhood Hits	289	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RPA1_MOUSE
θ value	0.62314 (rank : 105)	NC score	0.035940 (rank : 153)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

ZN326_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.034742 (rank : 159)
Query Neighborhood Hits	289	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

ARS2_MOUSE
θ value	0.813845 (rank : 107)	NC score	0.056089 (rank : 87)
Query Neighborhood Hits	289	Target Neighborhood Hits	212	Shared Neighborhood Hits	27
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CCAR1_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.048045 (rank : 109)
Query Neighborhood Hits	289	Target Neighborhood Hits	444	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

DSPP_MOUSE
θ value	0.813845 (rank : 109)	NC score	0.078721 (rank : 55)
Query Neighborhood Hits	289	Target Neighborhood Hits	491	Shared Neighborhood Hits	79
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

G3BP2_MOUSE
θ value	0.813845 (rank : 110)	NC score	0.031978 (rank : 175)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

HAP1_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.038603 (rank : 134)
Query Neighborhood Hits	289	Target Neighborhood Hits	606	Shared Neighborhood Hits	31
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

LYST_HUMAN
θ value	0.813845 (rank : 112)	NC score	0.021943 (rank : 218)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

PININ_HUMAN
θ value	0.813845 (rank : 113)	NC score	0.047053 (rank : 114)
Query Neighborhood Hits	289	Target Neighborhood Hits	753	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PKCB1_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.035374 (rank : 156)
Query Neighborhood Hits	289	Target Neighborhood Hits	488	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RPA1_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.033972 (rank : 165)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SIP1_MOUSE
θ value	0.813845 (rank : 116)	NC score	0.010360 (rank : 296)
Query Neighborhood Hits	289	Target Neighborhood Hits	870	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

TOP1_MOUSE
θ value	0.813845 (rank : 117)	NC score	0.040503 (rank : 128)
Query Neighborhood Hits	289	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

CACB2_MOUSE
θ value	1.06291 (rank : 118)	NC score	0.014559 (rank : 268)
Query Neighborhood Hits	289	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

LRCH2_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.014707 (rank : 265)
Query Neighborhood Hits	289	Target Neighborhood Hits	315	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH2_MOUSE
θ value	1.06291 (rank : 120)	NC score	0.013347 (rank : 275)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MAP1B_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.044742 (rank : 117)
Query Neighborhood Hits	289	Target Neighborhood Hits	903	Shared Neighborhood Hits	82
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MCM3_MOUSE
θ value	1.06291 (rank : 122)	NC score	0.016110 (rank : 261)
Query Neighborhood Hits	289	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

MINT_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.036973 (rank : 148)
Query Neighborhood Hits	289	Target Neighborhood Hits	1291	Shared Neighborhood Hits	89
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST4_HUMAN
θ value	1.06291 (rank : 124)	NC score	0.040087 (rank : 130)
Query Neighborhood Hits	289	Target Neighborhood Hits	671	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NKTR_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.032708 (rank : 168)
Query Neighborhood Hits	289	Target Neighborhood Hits	417	Shared Neighborhood Hits	66
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

REPS1_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.024278 (rank : 207)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SEC62_HUMAN
θ value	1.06291 (rank : 127)	NC score	0.049557 (rank : 104)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

SMCE1_HUMAN
θ value	1.06291 (rank : 128)	NC score	0.026539 (rank : 197)
Query Neighborhood Hits	289	Target Neighborhood Hits	272	Shared Neighborhood Hits	19
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

TF7L2_MOUSE
θ value	1.06291 (rank : 129)	NC score	0.021524 (rank : 220)
Query Neighborhood Hits	289	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

UBP47_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.029651 (rank : 183)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

YTDC1_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.060351 (rank : 80)
Query Neighborhood Hits	289	Target Neighborhood Hits	458	Shared Neighborhood Hits	75
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

AP2A1_HUMAN
θ value	1.38821 (rank : 132)	NC score	0.025356 (rank : 204)
Query Neighborhood Hits	289	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_MOUSE
θ value	1.38821 (rank : 133)	NC score	0.025371 (rank : 203)
Query Neighborhood Hits	289	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

BMS1_HUMAN
θ value	1.38821 (rank : 134)	NC score	0.040723 (rank : 127)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	23
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CALR_HUMAN
θ value	1.38821 (rank : 135)	NC score	0.028525 (rank : 187)
Query Neighborhood Hits	289	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CALR_MOUSE
θ value	1.38821 (rank : 136)	NC score	0.026162 (rank : 199)
Query Neighborhood Hits	289	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CT032_HUMAN
θ value	1.38821 (rank : 137)	NC score	0.016412 (rank : 257)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

FA21C_HUMAN
θ value	1.38821 (rank : 138)	NC score	0.047084 (rank : 113)
Query Neighborhood Hits	289	Target Neighborhood Hits	194	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

MDN1_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.082607 (rank : 51)
Query Neighborhood Hits	289	Target Neighborhood Hits	662	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYPT1_MOUSE
θ value	1.38821 (rank : 140)	NC score	0.026918 (rank : 196)
Query Neighborhood Hits	289	Target Neighborhood Hits	539	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NPHP1_MOUSE
θ value	1.38821 (rank : 141)	NC score	0.016217 (rank : 260)
Query Neighborhood Hits	289	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NSBP1_MOUSE
θ value	1.38821 (rank : 142)	NC score	0.130618 (rank : 28)
Query Neighborhood Hits	289	Target Neighborhood Hits	681	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PAX7_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.005863 (rank : 308)
Query Neighborhood Hits	289	Target Neighborhood Hits	422	Shared Neighborhood Hits	7
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

PKHA5_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.056208 (rank : 85)
Query Neighborhood Hits	289	Target Neighborhood Hits	455	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RBM28_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.021948 (rank : 217)
Query Neighborhood Hits	289	Target Neighborhood Hits	307	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

RGP1_MOUSE
θ value	1.38821 (rank : 146)	NC score	0.037082 (rank : 147)
Query Neighborhood Hits	289	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RHG12_MOUSE
θ value	1.38821 (rank : 147)	NC score	0.010608 (rank : 294)
Query Neighborhood Hits	289	Target Neighborhood Hits	204	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RIOK1_HUMAN
θ value	1.38821 (rank : 148)	NC score	0.029226 (rank : 184)
Query Neighborhood Hits	289	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

RPTN_MOUSE
θ value	1.38821 (rank : 149)	NC score	0.047494 (rank : 111)
Query Neighborhood Hits	289	Target Neighborhood Hits	650	Shared Neighborhood Hits	94
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SET1A_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.034043 (rank : 164)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	44
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SET_MOUSE
θ value	1.38821 (rank : 151)	NC score	0.026957 (rank : 195)
Query Neighborhood Hits	289	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

SIP1_HUMAN
θ value	1.38821 (rank : 152)	NC score	0.010035 (rank : 298)
Query Neighborhood Hits	289	Target Neighborhood Hits	832	Shared Neighborhood Hits	31
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

THOC2_HUMAN
θ value	1.38821 (rank : 153)	NC score	0.040289 (rank : 129)
Query Neighborhood Hits	289	Target Neighborhood Hits	337	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

UBP47_HUMAN
θ value	1.38821 (rank : 154)	NC score	0.021950 (rank : 216)
Query Neighborhood Hits	289	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

ABTAP_MOUSE
θ value	1.81305 (rank : 155)	NC score	0.036433 (rank : 151)
Query Neighborhood Hits	289	Target Neighborhood Hits	381	Shared Neighborhood Hits	40
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AN32E_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.064874 (rank : 70)
Query Neighborhood Hits	289	Target Neighborhood Hits	291	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

BRMS1_MOUSE
θ value	1.81305 (rank : 157)	NC score	0.036298 (rank : 152)
Query Neighborhood Hits	289	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N20	Gene names	Brms1
Domain Architecture	No domain graphic available
Description	Breast cancer metastasis-suppressor 1 homolog.

COVA1_HUMAN
θ value	1.81305 (rank : 158)	NC score	0.028594 (rank : 186)
Query Neighborhood Hits	289	Target Neighborhood Hits	416	Shared Neighborhood Hits	25
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

COVA1_MOUSE
θ value	1.81305 (rank : 159)	NC score	0.030707 (rank : 176)
Query Neighborhood Hits	289	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

JIP2_HUMAN
θ value	1.81305 (rank : 160)	NC score	0.016411 (rank : 258)
Query Neighborhood Hits	289	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KI21A_MOUSE
θ value	1.81305 (rank : 161)	NC score	0.017027 (rank : 251)
Query Neighborhood Hits	289	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

NFM_HUMAN
θ value	1.81305 (rank : 162)	NC score	0.017737 (rank : 247)
Query Neighborhood Hits	289	Target Neighborhood Hits	1328	Shared Neighborhood Hits	82
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NOP14_HUMAN
θ value	1.81305 (rank : 163)	NC score	0.050891 (rank : 98)
Query Neighborhood Hits	289	Target Neighborhood Hits	573	Shared Neighborhood Hits	80
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

RGP1_HUMAN
θ value	1.81305 (rank : 164)	NC score	0.032526 (rank : 169)
Query Neighborhood Hits	289	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

SH3BG_MOUSE
θ value	1.81305 (rank : 165)	NC score	0.027647 (rank : 189)
Query Neighborhood Hits	289	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WUZ7	Gene names	Sh3bgr
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein).

TAF3_MOUSE
θ value	1.81305 (rank : 166)	NC score	0.022612 (rank : 214)
Query Neighborhood Hits	289	Target Neighborhood Hits	463	Shared Neighborhood Hits	34
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

AN32A_HUMAN
θ value	2.36792 (rank : 167)	NC score	0.058397 (rank : 83)
Query Neighborhood Hits	289	Target Neighborhood Hits	234	Shared Neighborhood Hits	22
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

BLNK_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.020577 (rank : 224)
Query Neighborhood Hits	289	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CYLC1_HUMAN
θ value	2.36792 (rank : 169)	NC score	0.044189 (rank : 119)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	47
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

ENL_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.026351 (rank : 198)
Query Neighborhood Hits	289	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HMGB1_MOUSE
θ value	2.36792 (rank : 171)	NC score	0.019326 (rank : 232)
Query Neighborhood Hits	289	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

SRCH_HUMAN
θ value	2.36792 (rank : 172)	NC score	0.056143 (rank : 86)
Query Neighborhood Hits	289	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

THAP4_MOUSE
θ value	2.36792 (rank : 173)	NC score	0.019784 (rank : 229)
Query Neighborhood Hits	289	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

TOP1_HUMAN
θ value	2.36792 (rank : 174)	NC score	0.037796 (rank : 141)
Query Neighborhood Hits	289	Target Neighborhood Hits	207	Shared Neighborhood Hits	26
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ZCHC6_HUMAN
θ value	2.36792 (rank : 175)	NC score	0.018648 (rank : 243)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ALKB7_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.025205 (rank : 205)
Query Neighborhood Hits	289	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BT30, Q53FF3	Gene names	ALKBH7, SPATA11
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 7 precursor (Spermatogenesis- associated protein 11) (Spermatogenesis cell proliferation-related protein).

AP3B2_MOUSE
θ value	3.0926 (rank : 177)	NC score	0.035371 (rank : 157)
Query Neighborhood Hits	289	Target Neighborhood Hits	246	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

ARI4A_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.032315 (rank : 174)
Query Neighborhood Hits	289	Target Neighborhood Hits	434	Shared Neighborhood Hits	42
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BNC2_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.029775 (rank : 182)
Query Neighborhood Hits	289	Target Neighborhood Hits	439	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BRMS1_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.035312 (rank : 158)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCU9	Gene names	BRMS1
Domain Architecture	No domain graphic available
Description	Breast cancer metastasis-suppressor 1.

CN037_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.022722 (rank : 213)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

GPTC8_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.037488 (rank : 145)
Query Neighborhood Hits	289	Target Neighborhood Hits	366	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IWS1_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.118259 (rank : 31)
Query Neighborhood Hits	289	Target Neighborhood Hits	1258	Shared Neighborhood Hits	177
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1718_HUMAN
θ value	3.0926 (rank : 184)	NC score	0.011529 (rank : 289)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

KI21A_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.018743 (rank : 240)
Query Neighborhood Hits	289	Target Neighborhood Hits	1543	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MAP1B_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.042214 (rank : 123)
Query Neighborhood Hits	289	Target Neighborhood Hits	977	Shared Neighborhood Hits	77
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYO10_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.040806 (rank : 126)
Query Neighborhood Hits	289	Target Neighborhood Hits	920	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NFM_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.016727 (rank : 254)
Query Neighborhood Hits	289	Target Neighborhood Hits	1159	Shared Neighborhood Hits	74
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NRK_MOUSE
θ value	3.0926 (rank : 189)	NC score	0.002672 (rank : 312)
Query Neighborhood Hits	289	Target Neighborhood Hits	899	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

RBBP6_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.062797 (rank : 75)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBM13_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.032394 (rank : 172)
Query Neighborhood Hits	289	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXY0, Q5U5T1, Q86UC4, Q96SY6	Gene names	RBM13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13) (NNP78).

RBM13_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.036538 (rank : 149)
Query Neighborhood Hits	289	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGS0, Q921E0, Q9D5G6	Gene names	Rbm13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13).

RUFY2_MOUSE
θ value	3.0926 (rank : 193)	NC score	0.013218 (rank : 277)
Query Neighborhood Hits	289	Target Neighborhood Hits	820	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SEC62_MOUSE
θ value	3.0926 (rank : 194)	NC score	0.042245 (rank : 122)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

TRPV5_HUMAN
θ value	3.0926 (rank : 195)	NC score	0.012526 (rank : 282)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

U5S1_MOUSE
θ value	3.0926 (rank : 196)	NC score	0.011866 (rank : 284)
Query Neighborhood Hits	289	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

WBP11_MOUSE
θ value	3.0926 (rank : 197)	NC score	0.020362 (rank : 228)
Query Neighborhood Hits	289	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

AP2A2_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.022899 (rank : 211)
Query Neighborhood Hits	289	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.022938 (rank : 210)
Query Neighborhood Hits	289	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

APBB1_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.010594 (rank : 295)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APLP2_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.018356 (rank : 244)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	27
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

ATAD2_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.017320 (rank : 248)
Query Neighborhood Hits	289	Target Neighborhood Hits	322	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

CASQ2_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.011631 (rank : 287)
Query Neighborhood Hits	289	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

CHD4_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.019086 (rank : 235)
Query Neighborhood Hits	289	Target Neighborhood Hits	365	Shared Neighborhood Hits	30
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	4.03905 (rank : 205)	NC score	0.018221 (rank : 245)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CN120_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.016997 (rank : 252)
Query Neighborhood Hits	289	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEJ9, Q9Y400	Gene names	C14orf120
Domain Architecture
Description	Protein C14orf120.

HMGB1_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.017826 (rank : 246)
Query Neighborhood Hits	289	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

LRRF1_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.050152 (rank : 101)
Query Neighborhood Hits	289	Target Neighborhood Hits	625	Shared Neighborhood Hits	85
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

NCOR1_MOUSE
θ value	4.03905 (rank : 209)	NC score	0.029903 (rank : 181)
Query Neighborhood Hits	289	Target Neighborhood Hits	521	Shared Neighborhood Hits	50
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NCOR2_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.029913 (rank : 180)
Query Neighborhood Hits	289	Target Neighborhood Hits	790	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NOP14_MOUSE
θ value	4.03905 (rank : 211)	NC score	0.039030 (rank : 132)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

OSTP_MOUSE
θ value	4.03905 (rank : 212)	NC score	0.038517 (rank : 136)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

PAX7_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.004557 (rank : 311)
Query Neighborhood Hits	289	Target Neighborhood Hits	456	Shared Neighborhood Hits	8
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

PKHC1_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.030661 (rank : 177)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

PKHC1_MOUSE
θ value	4.03905 (rank : 215)	NC score	0.030281 (rank : 179)
Query Neighborhood Hits	289	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

RENT2_HUMAN
θ value	4.03905 (rank : 216)	NC score	0.032890 (rank : 167)
Query Neighborhood Hits	289	Target Neighborhood Hits	618	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RFXK_HUMAN
θ value	4.03905 (rank : 217)	NC score	0.023101 (rank : 209)
Query Neighborhood Hits	289	Target Neighborhood Hits	282	Shared Neighborhood Hits	10
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

SMBT1_HUMAN
θ value	4.03905 (rank : 218)	NC score	0.013822 (rank : 271)
Query Neighborhood Hits	289	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

SMBT1_MOUSE
θ value	4.03905 (rank : 219)	NC score	0.014955 (rank : 264)
Query Neighborhood Hits	289	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JMD1, Q6NZD3, Q8CFS1	Gene names	Sfmbt1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1.

SMUF1_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.019005 (rank : 237)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	4.03905 (rank : 221)	NC score	0.019003 (rank : 238)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

TXND2_MOUSE
θ value	4.03905 (rank : 222)	NC score	0.072075 (rank : 62)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	130
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

URP2_HUMAN
θ value	4.03905 (rank : 223)	NC score	0.037855 (rank : 140)
Query Neighborhood Hits	289	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

AFAD_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.018960 (rank : 239)
Query Neighborhood Hits	289	Target Neighborhood Hits	689	Shared Neighborhood Hits	43
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AP3B2_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.035685 (rank : 154)
Query Neighborhood Hits	289	Target Neighborhood Hits	246	Shared Neighborhood Hits	39
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

BNC2_MOUSE
θ value	5.27518 (rank : 226)	NC score	0.027528 (rank : 190)
Query Neighborhood Hits	289	Target Neighborhood Hits	456	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

BPTF_HUMAN
θ value	5.27518 (rank : 227)	NC score	0.034063 (rank : 163)
Query Neighborhood Hits	289	Target Neighborhood Hits	786	Shared Neighborhood Hits	79
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CCD96_MOUSE
θ value	5.27518 (rank : 228)	NC score	0.027175 (rank : 193)
Query Neighborhood Hits	289	Target Neighborhood Hits	704	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CTR9_MOUSE
θ value	5.27518 (rank : 229)	NC score	0.030518 (rank : 178)
Query Neighborhood Hits	289	Target Neighborhood Hits	427	Shared Neighborhood Hits	39
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

EHMT1_HUMAN
θ value	5.27518 (rank : 230)	NC score	0.020468 (rank : 226)
Query Neighborhood Hits	289	Target Neighborhood Hits	417	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

FGD4_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.013151 (rank : 278)
Query Neighborhood Hits	289	Target Neighborhood Hits	219	Shared Neighborhood Hits	19
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

GNAS3_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.035549 (rank : 155)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

M4K4_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.006843 (rank : 304)
Query Neighborhood Hits	289	Target Neighborhood Hits	1589	Shared Neighborhood Hits	59
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	5.27518 (rank : 234)	NC score	0.006729 (rank : 305)
Query Neighborhood Hits	289	Target Neighborhood Hits	1560	Shared Neighborhood Hits	56
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MBB1A_MOUSE
θ value	5.27518 (rank : 235)	NC score	0.019063 (rank : 236)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

MYO3B_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.004578 (rank : 310)
Query Neighborhood Hits	289	Target Neighborhood Hits	923	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

MYT1_MOUSE
θ value	5.27518 (rank : 237)	NC score	0.045865 (rank : 116)
Query Neighborhood Hits	289	Target Neighborhood Hits	385	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NCOR2_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.027449 (rank : 191)
Query Neighborhood Hits	289	Target Neighborhood Hits	870	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NUMA1_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.018677 (rank : 241)
Query Neighborhood Hits	289	Target Neighborhood Hits	1523	Shared Neighborhood Hits	69
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PACN2_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.014018 (rank : 270)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PTPRG_MOUSE
θ value	5.27518 (rank : 241)	NC score	0.002064 (rank : 313)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RHG25_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.070405 (rank : 64)
Query Neighborhood Hits	289	Target Neighborhood Hits	550	Shared Neighborhood Hits	52
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RPTN_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.037347 (rank : 146)
Query Neighborhood Hits	289	Target Neighborhood Hits	406	Shared Neighborhood Hits	56
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

TMC1_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.011214 (rank : 292)
Query Neighborhood Hits	289	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDI8	Gene names	TMC1
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 1.

AP3B1_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.037495 (rank : 144)
Query Neighborhood Hits	289	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DC1I2_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.006431 (rank : 307)
Query Neighborhood Hits	289	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

GOGB1_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.027842 (rank : 188)
Query Neighborhood Hits	289	Target Neighborhood Hits	2297	Shared Neighborhood Hits	131
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IF4G1_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.005690 (rank : 309)
Query Neighborhood Hits	289	Target Neighborhood Hits	347	Shared Neighborhood Hits	11
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IL1A_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.012948 (rank : 280)
Query Neighborhood Hits	289	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P01583, Q7RU02	Gene names	IL1A, IL1F1
Domain Architecture
Description	Interleukin-1 alpha precursor (IL-1 alpha) (Hematopoietin-1).

NELFE_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.014648 (rank : 267)
Query Neighborhood Hits	289	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

PQBP1_MOUSE
θ value	6.88961 (rank : 251)	NC score	0.020985 (rank : 222)
Query Neighborhood Hits	289	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

REST_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.016249 (rank : 259)
Query Neighborhood Hits	289	Target Neighborhood Hits	1506	Shared Neighborhood Hits	78
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SEC63_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.077235 (rank : 58)
Query Neighborhood Hits	289	Target Neighborhood Hits	586	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SET_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.022283 (rank : 215)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

SPT5H_MOUSE
θ value	6.88961 (rank : 255)	NC score	0.016931 (rank : 253)
Query Neighborhood Hits	289	Target Neighborhood Hits	437	Shared Neighborhood Hits	22
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

STS1_HUMAN
θ value	6.88961 (rank : 256)	NC score	0.011609 (rank : 288)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.011647 (rank : 286)
Query Neighborhood Hits	289	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

TAI12_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.011296 (rank : 291)
Query Neighborhood Hits	289	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TAI12_MOUSE
θ value	6.88961 (rank : 259)	NC score	0.011438 (rank : 290)
Query Neighborhood Hits	289	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TCRG1_MOUSE
θ value	6.88961 (rank : 260)	NC score	0.032396 (rank : 171)
Query Neighborhood Hits	289	Target Neighborhood Hits	947	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TR150_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.034318 (rank : 162)
Query Neighborhood Hits	289	Target Neighborhood Hits	313	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TXD13_MOUSE
θ value	6.88961 (rank : 262)	NC score	0.019419 (rank : 231)
Query Neighborhood Hits	289	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

UBF1_MOUSE
θ value	6.88961 (rank : 263)	NC score	0.049963 (rank : 102)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	65
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

ACINU_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.037542 (rank : 143)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ALKB7_MOUSE
θ value	8.99809 (rank : 265)	NC score	0.018654 (rank : 242)
Query Neighborhood Hits	289	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D6Z0, Q8K1H3, Q9CY41, Q9D942	Gene names	Alkbh7, Spata11
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 7 precursor.

ATRX_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.034540 (rank : 161)
Query Neighborhood Hits	289	Target Neighborhood Hits	682	Shared Neighborhood Hits	82
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BMP2K_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.006529 (rank : 306)
Query Neighborhood Hits	289	Target Neighborhood Hits	867	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

BRWD1_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.009728 (rank : 299)
Query Neighborhood Hits	289	Target Neighborhood Hits	448	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CASC3_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.017245 (rank : 250)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CX020_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.012064 (rank : 283)
Query Neighborhood Hits	289	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDZ0, Q5JXE5	Gene names	CXorf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf20.

EP15R_MOUSE
θ value	8.99809 (rank : 271)	NC score	0.025533 (rank : 201)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	86
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

ERIC1_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.126365 (rank : 29)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	122
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

HMG1X_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.014540 (rank : 269)
Query Neighborhood Hits	289	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HS90A_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.009138 (rank : 301)
Query Neighborhood Hits	289	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

MPP10_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.024608 (rank : 206)
Query Neighborhood Hits	289	Target Neighborhood Hits	306	Shared Neighborhood Hits	34
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

PCAF_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.010888 (rank : 293)
Query Neighborhood Hits	289	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PCQAP_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.009614 (rank : 300)
Query Neighborhood Hits	289	Target Neighborhood Hits	506	Shared Neighborhood Hits	20
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PEPL_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.016440 (rank : 256)
Query Neighborhood Hits	289	Target Neighborhood Hits	1141	Shared Neighborhood Hits	72
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PITX2_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.002015 (rank : 314)
Query Neighborhood Hits	289	Target Neighborhood Hits	383	Shared Neighborhood Hits	8
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

PP2CG_MOUSE
θ value	8.99809 (rank : 280)	NC score	0.013652 (rank : 272)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

SPBP_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.017277 (rank : 249)
Query Neighborhood Hits	289	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P15501	Gene names	Sbp
Domain Architecture
Description	Prostatic spermine-binding protein precursor (SBP) (Major prostatic secretory glycoprotein) (P25).

SPRL1_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.038534 (rank : 135)
Query Neighborhood Hits	289	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPT16_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.020448 (rank : 227)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5B9, Q6GMT8, Q6P2F1, Q6PJM1, Q9NRX0	Gene names	SUPT16H, FACT140, FACTP140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin-specific transcription elongation factor 140 kDa subunit).

SPT16_MOUSE
θ value	8.99809 (rank : 284)	NC score	0.020498 (rank : 225)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q920B9, Q3TZ48, Q3UFH0, Q921H4	Gene names	Supt16h, Fact140, Factp140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin- specific transcription elongation factor 140 kDa subunit).

TOP2A_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.007455 (rank : 303)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TPR_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.027433 (rank : 192)
Query Neighborhood Hits	289	Target Neighborhood Hits	1921	Shared Neighborhood Hits	113
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TXD13_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.026058 (rank : 200)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

ZMY15_HUMAN
θ value	8.99809 (rank : 288)	NC score	0.015458 (rank : 263)
Query Neighborhood Hits	289	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

ZN326_HUMAN
θ value	8.99809 (rank : 289)	NC score	0.025423 (rank : 202)
Query Neighborhood Hits	289	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

AKA12_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.077498 (rank : 57)
Query Neighborhood Hits	289	Target Neighborhood Hits	825	Shared Neighborhood Hits	130
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ASPH_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.050989 (rank : 97)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

C43BP_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.241560 (rank : 22)
Query Neighborhood Hits	289	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.237843 (rank : 23)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CC47_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.063207 (rank : 74)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

DDEF1_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.050774 (rank : 99)
Query Neighborhood Hits	289	Target Neighborhood Hits	592	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GBF1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.053091 (rank : 92)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

MTMRD_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.054119 (rank : 91)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

NASP_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.084814 (rank : 48)
Query Neighborhood Hits	289	Target Neighborhood Hits	709	Shared Neighborhood Hits	126
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NIPBL_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.061095 (rank : 78)
Query Neighborhood Hits	289	Target Neighborhood Hits	1311	Shared Neighborhood Hits	141
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.051061 (rank : 96)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	118
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PKHA3_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.272359 (rank : 21)
Query Neighborhood Hits	289	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.279176 (rank : 20)
Query Neighborhood Hits	289	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.066587 (rank : 67)
Query Neighborhood Hits	289	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.059584 (rank : 81)
Query Neighborhood Hits	289	Target Neighborhood Hits	591	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.082647 (rank : 50)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.085016 (rank : 47)
Query Neighborhood Hits	289	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.078583 (rank : 56)
Query Neighborhood Hits	289	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.082946 (rank : 49)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RBBP6_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.052567 (rank : 94)
Query Neighborhood Hits	289	Target Neighborhood Hits	1014	Shared Neighborhood Hits	106
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RHG25_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.073725 (rank : 61)
Query Neighborhood Hits	289	Target Neighborhood Hits	492	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SEC63_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.075095 (rank : 60)
Query Neighborhood Hits	289	Target Neighborhood Hits	601	Shared Neighborhood Hits	153
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TCAL3_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.057012 (rank : 84)
Query Neighborhood Hits	289	Target Neighborhood Hits	274	Shared Neighborhood Hits	96
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TCAL5_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.105455 (rank : 37)
Query Neighborhood Hits	289	Target Neighborhood Hits	806	Shared Neighborhood Hits	167
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.054180 (rank : 90)
Query Neighborhood Hits	289	Target Neighborhood Hits	1037	Shared Neighborhood Hits	116
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

VPS72_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.052196 (rank : 95)
Query Neighborhood Hits	289	Target Neighborhood Hits	286	Shared Neighborhood Hits	87
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

Hits sorted by NC score

OSBL8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL5_MOUSE
NC score	0.951066 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	289	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL5_HUMAN
NC score	0.943744 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	289	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSB10_HUMAN
NC score	0.844464 (rank : 4)	θ value	1.78386e-56 (rank : 5)
Query Neighborhood Hits	289	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_MOUSE
NC score	0.822209 (rank : 5)	θ value	2.84797e-54 (rank : 7)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
NC score	0.821889 (rank : 6)	θ value	5.73848e-55 (rank : 6)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
NC score	0.821218 (rank : 7)	θ value	2.84138e-62 (rank : 4)
Query Neighborhood Hits	289	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL2_HUMAN
NC score	0.754176 (rank : 8)	θ value	4.42448e-31 (rank : 10)
Query Neighborhood Hits	289	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
NC score	0.752198 (rank : 9)	θ value	2.42779e-29 (rank : 11)
Query Neighborhood Hits	289	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL7_HUMAN
NC score	0.691884 (rank : 10)	θ value	2.97466e-19 (rank : 16)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL6_HUMAN
NC score	0.682206 (rank : 11)	θ value	2.06002e-20 (rank : 14)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
NC score	0.677022 (rank : 12)	θ value	2.27762e-19 (rank : 15)
Query Neighborhood Hits	289	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP2_HUMAN
NC score	0.676271 (rank : 13)	θ value	8.65492e-19 (rank : 17)
Query Neighborhood Hits	289	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP1_HUMAN
NC score	0.676234 (rank : 14)	θ value	5.42112e-21 (rank : 12)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL6_MOUSE
NC score	0.673815 (rank : 15)	θ value	7.0802e-21 (rank : 13)
Query Neighborhood Hits	289	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBP2_MOUSE
NC score	0.664424 (rank : 16)	θ value	3.28887e-18 (rank : 18)
Query Neighborhood Hits	289	Target Neighborhood Hits	150	Shared Neighborhood Hits	36
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL3_HUMAN
NC score	0.663665 (rank : 17)	θ value	5.60996e-18 (rank : 19)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL1_MOUSE
NC score	0.524838 (rank : 18)	θ value	1.24399e-33 (rank : 9)
Query Neighborhood Hits	289	Target Neighborhood Hits	336	Shared Neighborhood Hits	31
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
NC score	0.512865 (rank : 19)	θ value	7.29293e-34 (rank : 8)
Query Neighborhood Hits	289	Target Neighborhood Hits	368	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.279176 (rank : 20)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	289	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.272359 (rank : 21)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	289	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.241560 (rank : 22)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	289	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.237843 (rank : 23)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

LEO1_MOUSE
NC score	0.158467 (rank : 24)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	289	Target Neighborhood Hits	946	Shared Neighborhood Hits	193
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.151479 (rank : 25)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	289	Target Neighborhood Hits	958	Shared Neighborhood Hits	187
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CYH4_MOUSE
NC score	0.146595 (rank : 26)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	289	Target Neighborhood Hits	134	Shared Neighborhood Hits	29
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.144098 (rank : 27)	θ value	0.00665767 (rank : 25)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

NSBP1_MOUSE
NC score	0.130618 (rank : 28)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	289	Target Neighborhood Hits	681	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ERIC1_HUMAN
NC score	0.126365 (rank : 29)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	122
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

CYH3_MOUSE
NC score	0.119498 (rank : 30)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	289	Target Neighborhood Hits	148	Shared Neighborhood Hits	27
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

IWS1_MOUSE
NC score	0.118259 (rank : 31)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	289	Target Neighborhood Hits	1258	Shared Neighborhood Hits	177
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_HUMAN
NC score	0.111565 (rank : 32)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	289	Target Neighborhood Hits	1241	Shared Neighborhood Hits	172
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DMP1_HUMAN
NC score	0.109883 (rank : 33)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	289	Target Neighborhood Hits	491	Shared Neighborhood Hits	105
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CYH1_MOUSE
NC score	0.107828 (rank : 34)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
NC score	0.107801 (rank : 35)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	289	Target Neighborhood Hits	184	Shared Neighborhood Hits	27
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

SWP70_MOUSE
NC score	0.106172 (rank : 36)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	289	Target Neighborhood Hits	1097	Shared Neighborhood Hits	87
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TCAL5_HUMAN
NC score	0.105455 (rank : 37)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	289	Target Neighborhood Hits	806	Shared Neighborhood Hits	167
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SWP70_HUMAN
NC score	0.104388 (rank : 38)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	289	Target Neighborhood Hits	973	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CYH3_HUMAN
NC score	0.103986 (rank : 39)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	289	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_HUMAN
NC score	0.102293 (rank : 40)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.102289 (rank : 41)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

PELP1_HUMAN
NC score	0.098036 (rank : 42)	θ value	0.000158464 (rank : 20)
Query Neighborhood Hits	289	Target Neighborhood Hits	596	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

VEZA_HUMAN
NC score	0.096048 (rank : 43)	θ value	0.000786445 (rank : 21)
Query Neighborhood Hits	289	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

SPRL1_MOUSE
NC score	0.092996 (rank : 44)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	289	Target Neighborhood Hits	403	Shared Neighborhood Hits	105
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

DMP1_MOUSE
NC score	0.088302 (rank : 45)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	289	Target Neighborhood Hits	498	Shared Neighborhood Hits	90
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
NC score	0.086053 (rank : 46)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	289	Target Neighborhood Hits	645	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PLEK2_MOUSE
NC score	0.085016 (rank : 47)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	289	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

NASP_HUMAN
NC score	0.084814 (rank : 48)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	289	Target Neighborhood Hits	709	Shared Neighborhood Hits	126
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PLEK_MOUSE
NC score	0.082946 (rank : 49)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK2_HUMAN
NC score	0.082647 (rank : 50)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

MDN1_HUMAN
NC score	0.082607 (rank : 51)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	289	Target Neighborhood Hits	662	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

DAXX_HUMAN
NC score	0.082309 (rank : 52)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	289	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

PELP1_MOUSE
NC score	0.081993 (rank : 53)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	289	Target Neighborhood Hits	709	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

AN32B_MOUSE
NC score	0.081612 (rank : 54)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	289	Target Neighborhood Hits	236	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

DSPP_MOUSE
NC score	0.078721 (rank : 55)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	289	Target Neighborhood Hits	491	Shared Neighborhood Hits	79
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PLEK_HUMAN
NC score	0.078583 (rank : 56)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	289	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

AKA12_HUMAN
NC score	0.077498 (rank : 57)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	289	Target Neighborhood Hits	825	Shared Neighborhood Hits	130
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

SEC63_HUMAN
NC score	0.077235 (rank : 58)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	289	Target Neighborhood Hits	586	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

AN32B_HUMAN
NC score	0.076077 (rank : 59)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	289	Target Neighborhood Hits	243	Shared Neighborhood Hits	27
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

SEC63_MOUSE
NC score	0.075095 (rank : 60)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	289	Target Neighborhood Hits	601	Shared Neighborhood Hits	153
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

RHG25_MOUSE
NC score	0.073725 (rank : 61)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	289	Target Neighborhood Hits	492	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TXND2_MOUSE
NC score	0.072075 (rank : 62)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	130
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

DAXX_MOUSE
NC score	0.070638 (rank : 63)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

RHG25_HUMAN
NC score	0.070405 (rank : 64)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	289	Target Neighborhood Hits	550	Shared Neighborhood Hits	52
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

HTSF1_MOUSE
NC score	0.069447 (rank : 65)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	289	Target Neighborhood Hits	425	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

ARS2_HUMAN
NC score	0.067567 (rank : 66)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

PKHA6_HUMAN
NC score	0.066587 (rank : 67)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	289	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GNAS3_MOUSE
NC score	0.066238 (rank : 68)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

NSBP1_HUMAN
NC score	0.066079 (rank : 69)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	289	Target Neighborhood Hits	251	Shared Neighborhood Hits	37
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

AN32E_HUMAN
NC score	0.064874 (rank : 70)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	289	Target Neighborhood Hits	291	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

HAP1_MOUSE
NC score	0.063862 (rank : 71)	θ value	0.00175202 (rank : 22)
Query Neighborhood Hits	289	Target Neighborhood Hits	388	Shared Neighborhood Hits	22
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

AN32A_MOUSE
NC score	0.063338 (rank : 72)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	289	Target Neighborhood Hits	254	Shared Neighborhood Hits	20
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.063338 (rank : 73)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	289	Target Neighborhood Hits	254	Shared Neighborhood Hits	20
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

CC47_MOUSE
NC score	0.063207 (rank : 74)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

RBBP6_HUMAN
NC score	0.062797 (rank : 75)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

HTSF1_HUMAN
NC score	0.062751 (rank : 76)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	41
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

UBF1_HUMAN
NC score	0.061802 (rank : 77)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	289	Target Neighborhood Hits	415	Shared Neighborhood Hits	58
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

NIPBL_HUMAN
NC score	0.061095 (rank : 78)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	289	Target Neighborhood Hits	1311	Shared Neighborhood Hits	141
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MYT1L_MOUSE
NC score	0.060651 (rank : 79)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	289	Target Neighborhood Hits	461	Shared Neighborhood Hits	49
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

YTDC1_HUMAN
NC score	0.060351 (rank : 80)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	289	Target Neighborhood Hits	458	Shared Neighborhood Hits	75
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

PKHA6_MOUSE
NC score	0.059584 (rank : 81)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	289	Target Neighborhood Hits	591	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MYT1L_HUMAN
NC score	0.058486 (rank : 82)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	289	Target Neighborhood Hits	471	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

AN32A_HUMAN
NC score	0.058397 (rank : 83)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	289	Target Neighborhood Hits	234	Shared Neighborhood Hits	22
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

TCAL3_HUMAN
NC score	0.057012 (rank : 84)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	289	Target Neighborhood Hits	274	Shared Neighborhood Hits	96
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

PKHA5_HUMAN
NC score	0.056208 (rank : 85)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	289	Target Neighborhood Hits	455	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SRCH_HUMAN
NC score	0.056143 (rank : 86)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	289	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

ARS2_MOUSE
NC score	0.056089 (rank : 87)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	289	Target Neighborhood Hits	212	Shared Neighborhood Hits	27
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

MYT1_HUMAN
NC score	0.055553 (rank : 88)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	289	Target Neighborhood Hits	475	Shared Neighborhood Hits	59
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

CCAR1_MOUSE
NC score	0.055221 (rank : 89)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	289	Target Neighborhood Hits	414	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

TGON2_HUMAN
NC score	0.054180 (rank : 90)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	289	Target Neighborhood Hits	1037	Shared Neighborhood Hits	116
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MTMRD_HUMAN
NC score	0.054119 (rank : 91)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

GBF1_HUMAN
NC score	0.053091 (rank : 92)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

PININ_MOUSE
NC score	0.052963 (rank : 93)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	289	Target Neighborhood Hits	777	Shared Neighborhood Hits	71
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RBBP6_MOUSE
NC score	0.052567 (rank : 94)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	289	Target Neighborhood Hits	1014	Shared Neighborhood Hits	106
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

VPS72_MOUSE
NC score	0.052196 (rank : 95)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	289	Target Neighborhood Hits	286	Shared Neighborhood Hits	87
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

NPBL_MOUSE
NC score	0.051061 (rank : 96)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	118
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ASPH_HUMAN
NC score	0.050989 (rank : 97)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

NOP14_HUMAN
NC score	0.050891 (rank : 98)	θ value	1.81305 (rank : 163)
Query Neighborhood Hits	289	Target Neighborhood Hits	573	Shared Neighborhood Hits	80
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

DDEF1_MOUSE
NC score	0.050774 (rank : 99)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	289	Target Neighborhood Hits	592	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PPIG_HUMAN
NC score	0.050299 (rank : 100)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	289	Target Neighborhood Hits	670	Shared Neighborhood Hits	94
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

LRRF1_HUMAN
NC score	0.050152 (rank : 101)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	289	Target Neighborhood Hits	625	Shared Neighborhood Hits	85
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

UBF1_MOUSE
NC score	0.049963 (rank : 102)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	65
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

RPGR1_MOUSE
NC score	0.049566 (rank : 103)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	289	Target Neighborhood Hits	713	Shared Neighborhood Hits	58
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SEC62_HUMAN
NC score	0.049557 (rank : 104)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

MYST3_MOUSE
NC score	0.049214 (rank : 105)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	289	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NCKX1_HUMAN
NC score	0.048992 (rank : 106)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	289	Target Neighborhood Hits	223	Shared Neighborhood Hits	31
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

CLSPN_HUMAN
NC score	0.048833 (rank : 107)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	289	Target Neighborhood Hits	433	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

TRI44_HUMAN
NC score	0.048240 (rank : 108)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	289	Target Neighborhood Hits	393	Shared Neighborhood Hits	38
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

CCAR1_HUMAN
NC score	0.048045 (rank : 109)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	289	Target Neighborhood Hits	444	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

TRI44_MOUSE
NC score	0.047978 (rank : 110)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	289	Target Neighborhood Hits	327	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

RPTN_MOUSE
NC score	0.047494 (rank : 111)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	289	Target Neighborhood Hits	650	Shared Neighborhood Hits	94
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

AP3B1_MOUSE
NC score	0.047363 (rank : 112)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	289	Target Neighborhood Hits	302	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

FA21C_HUMAN
NC score	0.047084 (rank : 113)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	289	Target Neighborhood Hits	194	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

PININ_HUMAN
NC score	0.047053 (rank : 114)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	289	Target Neighborhood Hits	753	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

URP2_MOUSE
NC score	0.046847 (rank : 115)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	289	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

MYT1_MOUSE
NC score	0.045865 (rank : 116)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	289	Target Neighborhood Hits	385	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

MAP1B_HUMAN
NC score	0.044742 (rank : 117)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	289	Target Neighborhood Hits	903	Shared Neighborhood Hits	82
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SMRC1_MOUSE
NC score	0.044266 (rank : 118)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	289	Target Neighborhood Hits	459	Shared Neighborhood Hits	76
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

CYLC1_HUMAN
NC score	0.044189 (rank : 119)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	47
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CENPB_MOUSE
NC score	0.043797 (rank : 120)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	289	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CENB5_HUMAN
NC score	0.043451 (rank : 121)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	289	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

SEC62_MOUSE
NC score	0.042245 (rank : 122)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

MAP1B_MOUSE
NC score	0.042214 (rank : 123)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	289	Target Neighborhood Hits	977	Shared Neighborhood Hits	77
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NUCL_MOUSE
NC score	0.041657 (rank : 124)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	289	Target Neighborhood Hits	425	Shared Neighborhood Hits	33
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

BAZ2B_HUMAN
NC score	0.040972 (rank : 125)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	289	Target Neighborhood Hits	803	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MYO10_HUMAN
NC score	0.040806 (rank : 126)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	289	Target Neighborhood Hits	920	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

BMS1_HUMAN
NC score	0.040723 (rank : 127)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	23
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

TOP1_MOUSE
NC score	0.040503 (rank : 128)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	289	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

THOC2_HUMAN
NC score	0.040289 (rank : 129)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	289	Target Neighborhood Hits	337	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

MYST4_HUMAN
NC score	0.040087 (rank : 130)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	289	Target Neighborhood Hits	671	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST3_HUMAN
NC score	0.039087 (rank : 131)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	289	Target Neighborhood Hits	772	Shared Neighborhood Hits	64
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NOP14_MOUSE
NC score	0.039030 (rank : 132)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CENB1_HUMAN
NC score	0.038868 (rank : 133)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	289	Target Neighborhood Hits	383	Shared Neighborhood Hits	28
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

HAP1_HUMAN
NC score	0.038603 (rank : 134)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	289	Target Neighborhood Hits	606	Shared Neighborhood Hits	31
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

SPRL1_HUMAN
NC score	0.038534 (rank : 135)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	289	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

OSTP_MOUSE
NC score	0.038517 (rank : 136)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

NUCL_HUMAN
NC score	0.038462 (rank : 137)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	289	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

HUWE1_HUMAN
NC score	0.038170 (rank : 138)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	289	Target Neighborhood Hits	443	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.037962 (rank : 139)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	289	Target Neighborhood Hits	406	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

URP2_HUMAN
NC score	0.037855 (rank : 140)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	289	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

TOP1_HUMAN
NC score	0.037796 (rank : 141)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	289	Target Neighborhood Hits	207	Shared Neighborhood Hits	26
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

NRDC_MOUSE
NC score	0.037794 (rank : 142)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	289	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

ACINU_HUMAN
NC score	0.037542 (rank : 143)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	289	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AP3B1_HUMAN
NC score	0.037495 (rank : 144)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	289	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

GPTC8_HUMAN
NC score	0.037488 (rank : 145)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	289	Target Neighborhood Hits	366	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

RPTN_HUMAN
NC score	0.037347 (rank : 146)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	289	Target Neighborhood Hits	406	Shared Neighborhood Hits	56
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RGP1_MOUSE
NC score	0.037082 (rank : 147)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	289	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

MINT_HUMAN
NC score	0.036973 (rank : 148)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	289	Target Neighborhood Hits	1291	Shared Neighborhood Hits	89
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RBM13_MOUSE
NC score	0.036538 (rank : 149)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	289	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGS0, Q921E0, Q9D5G6	Gene names	Rbm13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13).

NP1L3_MOUSE
NC score	0.036442 (rank : 150)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	34
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

ABTAP_MOUSE
NC score	0.036433 (rank : 151)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	289	Target Neighborhood Hits	381	Shared Neighborhood Hits	40
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

BRMS1_MOUSE
NC score	0.036298 (rank : 152)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	289	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N20	Gene names	Brms1
Domain Architecture	No domain graphic available
Description	Breast cancer metastasis-suppressor 1 homolog.

RPA1_MOUSE
NC score	0.035940 (rank : 153)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

AP3B2_HUMAN
NC score	0.035685 (rank : 154)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	289	Target Neighborhood Hits	246	Shared Neighborhood Hits	39
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

GNAS3_HUMAN
NC score	0.035549 (rank : 155)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

PKCB1_HUMAN
NC score	0.035374 (rank : 156)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	289	Target Neighborhood Hits	488	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

AP3B2_MOUSE
NC score	0.035371 (rank : 157)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	289	Target Neighborhood Hits	246	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

BRMS1_HUMAN
NC score	0.035312 (rank : 158)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	289	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCU9	Gene names	BRMS1
Domain Architecture	No domain graphic available
Description	Breast cancer metastasis-suppressor 1.

ZN326_MOUSE
NC score	0.034742 (rank : 159)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	289	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

WDR43_HUMAN
NC score	0.034554 (rank : 160)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	289	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

ATRX_MOUSE
NC score	0.034540 (rank : 161)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	289	Target Neighborhood Hits	682	Shared Neighborhood Hits	82
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

TR150_HUMAN
NC score	0.034318 (rank : 162)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	289	Target Neighborhood Hits	313	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

BPTF_HUMAN
NC score	0.034063 (rank : 163)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	289	Target Neighborhood Hits	786	Shared Neighborhood Hits	79
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SET1A_HUMAN
NC score	0.034043 (rank : 164)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	289	Target Neighborhood Hits	690	Shared Neighborhood Hits	44
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

RPA1_HUMAN
NC score	0.033972 (rank : 165)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	15
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

G3BP2_HUMAN
NC score	0.033859 (rank : 166)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

RENT2_HUMAN
NC score	0.032890 (rank : 167)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	289	Target Neighborhood Hits	618	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

NKTR_MOUSE
NC score	0.032708 (rank : 168)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	289	Target Neighborhood Hits	417	Shared Neighborhood Hits	66
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RGP1_HUMAN
NC score	0.032526 (rank : 169)	θ value	1.81305 (rank : 164)
Query Neighborhood Hits	289	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

HES1_HUMAN
NC score	0.032443 (rank : 170)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	289	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

TCRG1_MOUSE
NC score	0.032396 (rank : 171)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	289	Target Neighborhood Hits	947	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RBM13_HUMAN
NC score	0.032394 (rank : 172)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	289	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXY0, Q5U5T1, Q86UC4, Q96SY6	Gene names	RBM13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13) (NNP78).

HES1_MOUSE
NC score	0.032320 (rank : 173)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	289	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

ARI4A_HUMAN
NC score	0.032315 (rank : 174)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	289	Target Neighborhood Hits	434	Shared Neighborhood Hits	42
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

G3BP2_MOUSE
NC score	0.031978 (rank : 175)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

COVA1_MOUSE
NC score	0.030707 (rank : 176)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	289	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

PKHC1_HUMAN
NC score	0.030661 (rank : 177)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

CTR9_MOUSE
NC score	0.030518 (rank : 178)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	289	Target Neighborhood Hits	427	Shared Neighborhood Hits	39
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

PKHC1_MOUSE
NC score	0.030281 (rank : 179)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	289	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

NCOR2_MOUSE
NC score	0.029913 (rank : 180)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	289	Target Neighborhood Hits	790	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NCOR1_MOUSE
NC score	0.029903 (rank : 181)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	289	Target Neighborhood Hits	521	Shared Neighborhood Hits	50
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

BNC2_HUMAN
NC score	0.029775 (rank : 182)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	289	Target Neighborhood Hits	439	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

UBP47_MOUSE
NC score	0.029651 (rank : 183)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

RIOK1_HUMAN
NC score	0.029226 (rank : 184)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	289	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

S39A6_HUMAN
NC score	0.028809 (rank : 185)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	289	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q13433, Q8IXR3, Q96HP5	Gene names	SLC39A6, LIV1
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Estrogen-regulated protein LIV-1).

COVA1_HUMAN
NC score	0.028594 (rank : 186)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	289	Target Neighborhood Hits	416	Shared Neighborhood Hits	25
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CALR_HUMAN
NC score	0.028525 (rank : 187)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	289	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

GOGB1_HUMAN
NC score	0.027842 (rank : 188)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	289	Target Neighborhood Hits	2297	Shared Neighborhood Hits	131
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SH3BG_MOUSE
NC score	0.027647 (rank : 189)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	289	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WUZ7	Gene names	Sh3bgr
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein).

BNC2_MOUSE
NC score	0.027528 (rank : 190)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	289	Target Neighborhood Hits	456	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

NCOR2_HUMAN
NC score	0.027449 (rank : 191)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	289	Target Neighborhood Hits	870	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TPR_HUMAN
NC score	0.027433 (rank : 192)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	289	Target Neighborhood Hits	1921	Shared Neighborhood Hits	113
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCD96_MOUSE
NC score	0.027175 (rank : 193)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	289	Target Neighborhood Hits	704	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

UBP35_HUMAN
NC score	0.027086 (rank : 194)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	289	Target Neighborhood Hits	223	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

SET_MOUSE
NC score	0.026957 (rank : 195)	θ value	1.38821 (rank : 151)
Query Neighborhood Hits	289	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

MYPT1_MOUSE
NC score	0.026918 (rank : 196)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	289	Target Neighborhood Hits	539	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

SMCE1_HUMAN
NC score	0.026539 (rank : 197)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	289	Target Neighborhood Hits	272	Shared Neighborhood Hits	19
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

ENL_HUMAN
NC score	0.026351 (rank : 198)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	289	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

CALR_MOUSE
NC score	0.026162 (rank : 199)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	289	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

TXD13_HUMAN
NC score	0.026058 (rank : 200)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

EP15R_MOUSE
NC score	0.025533 (rank : 201)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	86
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

ZN326_HUMAN
NC score	0.025423 (rank : 202)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	289	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

AP2A1_MOUSE
NC score	0.025371 (rank : 203)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	289	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_HUMAN
NC score	0.025356 (rank : 204)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	289	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

ALKB7_HUMAN
NC score	0.025205 (rank : 205)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	289	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BT30, Q53FF3	Gene names	ALKBH7, SPATA11
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 7 precursor (Spermatogenesis- associated protein 11) (Spermatogenesis cell proliferation-related protein).

MPP10_HUMAN
NC score	0.024608 (rank : 206)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	289	Target Neighborhood Hits	306	Shared Neighborhood Hits	34
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

REPS1_HUMAN
NC score	0.024278 (rank : 207)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

TF7L2_HUMAN
NC score	0.024099 (rank : 208)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

RFXK_HUMAN
NC score	0.023101 (rank : 209)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	289	Target Neighborhood Hits	282	Shared Neighborhood Hits	10
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

AP2A2_MOUSE
NC score	0.022938 (rank : 210)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	289	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A2_HUMAN
NC score	0.022899 (rank : 211)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	289	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

CKAP4_HUMAN
NC score	0.022807 (rank : 212)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	289	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CN037_HUMAN
NC score	0.022722 (rank : 213)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

TAF3_MOUSE
NC score	0.022612 (rank : 214)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	289	Target Neighborhood Hits	463	Shared Neighborhood Hits	34
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SET_HUMAN
NC score	0.022283 (rank : 215)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	289	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

UBP47_HUMAN
NC score	0.021950 (rank : 216)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	289	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

RBM28_HUMAN
NC score	0.021948 (rank : 217)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	289	Target Neighborhood Hits	307	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

LYST_HUMAN
NC score	0.021943 (rank : 218)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

PEG3_MOUSE
NC score	0.021624 (rank : 219)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	289	Target Neighborhood Hits	1101	Shared Neighborhood Hits	106
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TF7L2_MOUSE
NC score	0.021524 (rank : 220)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	289	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

MYH9_MOUSE
NC score	0.020991 (rank : 221)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	289	Target Neighborhood Hits	1829	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PQBP1_MOUSE
NC score	0.020985 (rank : 222)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	289	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

EP400_MOUSE
NC score	0.020944 (rank : 223)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	289	Target Neighborhood Hits	592	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

BLNK_HUMAN
NC score	0.020577 (rank : 224)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	289	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

SPT16_MOUSE
NC score	0.020498 (rank : 225)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q920B9, Q3TZ48, Q3UFH0, Q921H4	Gene names	Supt16h, Fact140, Factp140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin- specific transcription elongation factor 140 kDa subunit).

EHMT1_HUMAN
NC score	0.020468 (rank : 226)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	289	Target Neighborhood Hits	417	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SPT16_HUMAN
NC score	0.020448 (rank : 227)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5B9, Q6GMT8, Q6P2F1, Q6PJM1, Q9NRX0	Gene names	SUPT16H, FACT140, FACTP140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin-specific transcription elongation factor 140 kDa subunit).

WBP11_MOUSE
NC score	0.020362 (rank : 228)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	289	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

THAP4_MOUSE
NC score	0.019784 (rank : 229)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	289	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

MYH3_HUMAN
NC score	0.019520 (rank : 230)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	289	Target Neighborhood Hits	1660	Shared Neighborhood Hits	89
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TXD13_MOUSE
NC score	0.019419 (rank : 231)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	289	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

HMGB1_MOUSE
NC score	0.019326 (rank : 232)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	289	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

ATBF1_HUMAN
NC score	0.019317 (rank : 233)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	289	Target Neighborhood Hits	1547	Shared Neighborhood Hits	39
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CHD8_HUMAN
NC score	0.019123 (rank : 234)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD4_HUMAN
NC score	0.019086 (rank : 235)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	289	Target Neighborhood Hits	365	Shared Neighborhood Hits	30
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

MBB1A_MOUSE
NC score	0.019063 (rank : 236)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

SMUF1_HUMAN
NC score	0.019005 (rank : 237)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.019003 (rank : 238)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

AFAD_HUMAN
NC score	0.018960 (rank : 239)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	289	Target Neighborhood Hits	689	Shared Neighborhood Hits	43
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

KI21A_HUMAN
NC score	0.018743 (rank : 240)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	289	Target Neighborhood Hits	1543	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

NUMA1_HUMAN
NC score	0.018677 (rank : 241)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	289	Target Neighborhood Hits	1523	Shared Neighborhood Hits	69
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ALKB7_MOUSE
NC score	0.018654 (rank : 242)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	289	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D6Z0, Q8K1H3, Q9CY41, Q9D942	Gene names	Alkbh7, Spata11
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 7 precursor.

ZCHC6_HUMAN
NC score	0.018648 (rank : 243)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

APLP2_MOUSE
NC score	0.018356 (rank : 244)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	27
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

CHD4_MOUSE
NC score	0.018221 (rank : 245)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	289	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

HMGB1_HUMAN
NC score	0.017826 (rank : 246)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	289	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

NFM_HUMAN
NC score	0.017737 (rank : 247)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	289	Target Neighborhood Hits	1328	Shared Neighborhood Hits	82
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

ATAD2_HUMAN
NC score	0.017320 (rank : 248)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	289	Target Neighborhood Hits	322	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SPBP_MOUSE
NC score	0.017277 (rank : 249)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	289	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P15501	Gene names	Sbp
Domain Architecture
Description	Prostatic spermine-binding protein precursor (SBP) (Major prostatic secretory glycoprotein) (P25).

CASC3_MOUSE
NC score	0.017245 (rank : 250)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

KI21A_MOUSE
NC score	0.017027 (rank : 251)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	289	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

CN120_HUMAN
NC score	0.016997 (rank : 252)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	289	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEJ9, Q9Y400	Gene names	C14orf120
Domain Architecture
Description	Protein C14orf120.

SPT5H_MOUSE
NC score	0.016931 (rank : 253)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	289	Target Neighborhood Hits	437	Shared Neighborhood Hits	22
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

NFM_MOUSE
NC score	0.016727 (rank : 254)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	289	Target Neighborhood Hits	1159	Shared Neighborhood Hits	74
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PRDM2_HUMAN
NC score	0.016725 (rank : 255)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	289	Target Neighborhood Hits	1135	Shared Neighborhood Hits	39
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PEPL_HUMAN
NC score	0.016440 (rank : 256)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	289	Target Neighborhood Hits	1141	Shared Neighborhood Hits	72
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CT032_HUMAN
NC score	0.016412 (rank : 257)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

JIP2_HUMAN
NC score	0.016411 (rank : 258)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	289	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

REST_MOUSE
NC score	0.016249 (rank : 259)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	289	Target Neighborhood Hits	1506	Shared Neighborhood Hits	78
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

NPHP1_MOUSE
NC score	0.016217 (rank : 260)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	289	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

MCM3_MOUSE
NC score	0.016110 (rank : 261)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	289	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

CD2L1_MOUSE
NC score	0.015928 (rank : 262)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	289	Target Neighborhood Hits	1463	Shared Neighborhood Hits	84
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

ZMY15_HUMAN
NC score	0.015458 (rank : 263)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	289	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

SMBT1_MOUSE
NC score	0.014955 (rank : 264)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	289	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JMD1, Q6NZD3, Q8CFS1	Gene names	Sfmbt1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1.

LRCH2_HUMAN
NC score	0.014707 (rank : 265)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	289	Target Neighborhood Hits	315	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

TCF8_HUMAN
NC score	0.014675 (rank : 266)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	289	Target Neighborhood Hits	1057	Shared Neighborhood Hits	61
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

NELFE_HUMAN
NC score	0.014648 (rank : 267)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	289	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

CACB2_MOUSE
NC score	0.014559 (rank : 268)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	289	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

HMG1X_HUMAN
NC score	0.014540 (rank : 269)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	289	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

PACN2_MOUSE
NC score	0.014018 (rank : 270)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SMBT1_HUMAN
NC score	0.013822 (rank : 271)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	289	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

PP2CG_MOUSE
NC score	0.013652 (rank : 272)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

CD2L1_HUMAN
NC score	0.013585 (rank : 273)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	289	Target Neighborhood Hits	1467	Shared Neighborhood Hits	78
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

FBXW7_HUMAN
NC score	0.013560 (rank : 274)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	289	Target Neighborhood Hits	433	Shared Neighborhood Hits	24
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

LRCH2_MOUSE
NC score	0.013347 (rank : 275)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

TCF8_MOUSE
NC score	0.013284 (rank : 276)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	289	Target Neighborhood Hits	1067	Shared Neighborhood Hits	48
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

RUFY2_MOUSE
NC score	0.013218 (rank : 277)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	289	Target Neighborhood Hits	820	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

FGD4_HUMAN
NC score	0.013151 (rank : 278)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	289	Target Neighborhood Hits	219	Shared Neighborhood Hits	19
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

CD2L2_HUMAN
NC score	0.013020 (rank : 279)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	289	Target Neighborhood Hits	1439	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

IL1A_HUMAN
NC score	0.012948 (rank : 280)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	289	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P01583, Q7RU02	Gene names	IL1A, IL1F1
Domain Architecture
Description	Interleukin-1 alpha precursor (IL-1 alpha) (Hematopoietin-1).

TTBK1_HUMAN
NC score	0.012634 (rank : 281)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	289	Target Neighborhood Hits	1058	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TRPV5_HUMAN
NC score	0.012526 (rank : 282)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

CX020_HUMAN
NC score	0.012064 (rank : 283)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	289	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDZ0, Q5JXE5	Gene names	CXorf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf20.

U5S1_MOUSE
NC score	0.011866 (rank : 284)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	289	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

ROCK1_MOUSE
NC score	0.011650 (rank : 285)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	289	Target Neighborhood Hits	2126	Shared Neighborhood Hits	77
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

STS1_MOUSE
NC score	0.011647 (rank : 286)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	289	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

CASQ2_HUMAN
NC score	0.011631 (rank : 287)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	289	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

STS1_HUMAN
NC score	0.011609 (rank : 288)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

K1718_HUMAN
NC score	0.011529 (rank : 289)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

TAI12_MOUSE
NC score	0.011438 (rank : 290)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	289	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TAI12_HUMAN
NC score	0.011296 (rank : 291)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	289	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TMC1_HUMAN
NC score	0.011214 (rank : 292)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	289	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDI8	Gene names	TMC1
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 1.

PCAF_HUMAN
NC score	0.010888 (rank : 293)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	289	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

RHG12_MOUSE
NC score	0.010608 (rank : 294)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	289	Target Neighborhood Hits	204	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

APBB1_MOUSE
NC score	0.010594 (rank : 295)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

SIP1_MOUSE
NC score	0.010360 (rank : 296)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	289	Target Neighborhood Hits	870	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

BMP2K_MOUSE
NC score	0.010080 (rank : 297)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	289	Target Neighborhood Hits	874	Shared Neighborhood Hits	27
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

SIP1_HUMAN
NC score	0.010035 (rank : 298)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	289	Target Neighborhood Hits	832	Shared Neighborhood Hits	31
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

BRWD1_HUMAN
NC score	0.009728 (rank : 299)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	289	Target Neighborhood Hits	448	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

PCQAP_MOUSE
NC score	0.009614 (rank : 300)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	289	Target Neighborhood Hits	506	Shared Neighborhood Hits	20
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

HS90A_HUMAN
NC score	0.009138 (rank : 301)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	289	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

ROCK1_HUMAN
NC score	0.008630 (rank : 302)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	289	Target Neighborhood Hits	2000	Shared Neighborhood Hits	70
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

TOP2A_HUMAN
NC score	0.007455 (rank : 303)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	289	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

M4K4_HUMAN
NC score	0.006843 (rank : 304)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	289	Target Neighborhood Hits	1589	Shared Neighborhood Hits	59
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
NC score	0.006729 (rank : 305)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	289	Target Neighborhood Hits	1560	Shared Neighborhood Hits	56
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

BMP2K_HUMAN
NC score	0.006529 (rank : 306)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	289	Target Neighborhood Hits	867	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

DC1I2_MOUSE
NC score	0.006431 (rank : 307)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	289	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

PAX7_MOUSE
NC score	0.005863 (rank : 308)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	289	Target Neighborhood Hits	422	Shared Neighborhood Hits	7
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

IF4G1_HUMAN
NC score	0.005690 (rank : 309)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	289	Target Neighborhood Hits	347	Shared Neighborhood Hits	11
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MYO3B_HUMAN
NC score	0.004578 (rank : 310)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	289	Target Neighborhood Hits	923	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

PAX7_HUMAN
NC score	0.004557 (rank : 311)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	289	Target Neighborhood Hits	456	Shared Neighborhood Hits	8
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

NRK_MOUSE
NC score	0.002672 (rank : 312)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	289	Target Neighborhood Hits	899	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

PTPRG_MOUSE
NC score	0.002064 (rank : 313)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PITX2_MOUSE
NC score	0.002015 (rank : 314)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	289	Target Neighborhood Hits	383	Shared Neighborhood Hits	8
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

GZF1_HUMAN
NC score	-0.001313 (rank : 315)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	289	Target Neighborhood Hits	854	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H116, Q96N08, Q9BQK9, Q9H117, Q9H6W6	Gene names	GZF1, ZBTB23, ZNF336
Domain Architecture
Description	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336) (Zinc finger and BTB domain-containing protein 23).