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Network neighborhood for query Sequence : OSBL5_HUMAN

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OSBL5_HUMAN
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBL5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	0 (rank : 2)	NC score	0.988950 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL8_HUMAN
θ value	0 (rank : 3)	NC score	0.943744 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	289	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB10_HUMAN
θ value	2.25659e-51 (rank : 4)	NC score	0.859911 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_HUMAN
θ value	2.94719e-51 (rank : 5)	NC score	0.835616 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_MOUSE
θ value	8.57503e-51 (rank : 6)	NC score	0.835805 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
θ value	7.25919e-50 (rank : 7)	NC score	0.832354 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	138	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL1_MOUSE
θ value	9.8567e-31 (rank : 8)	NC score	0.534861 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	336	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
θ value	3.17079e-29 (rank : 9)	NC score	0.522859 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL2_HUMAN
θ value	3.50572e-28 (rank : 10)	NC score	0.770066 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
θ value	1.24688e-25 (rank : 11)	NC score	0.767267 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL6_HUMAN
θ value	8.93572e-24 (rank : 12)	NC score	0.704809 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	7.56453e-23 (rank : 13)	NC score	0.696028 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBP2_HUMAN
θ value	1.09232e-21 (rank : 14)	NC score	0.692080 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	154	Shared Neighborhood Hits	32
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	5.42112e-21 (rank : 15)	NC score	0.683419 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	150	Shared Neighborhood Hits	28
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL3_MOUSE
θ value	1.5773e-20 (rank : 16)	NC score	0.696496 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL7_HUMAN
θ value	1.02238e-19 (rank : 17)	NC score	0.711323 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL3_HUMAN
θ value	5.07402e-19 (rank : 18)	NC score	0.682643 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP1_HUMAN
θ value	2.5182e-18 (rank : 19)	NC score	0.688193 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	180	Shared Neighborhood Hits	30
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CYH4_MOUSE
θ value	0.0193708 (rank : 20)	NC score	0.121505 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	134	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

MYPN_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.020327 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	421	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

CYH4_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.118600 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

BRD2_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.020652 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

GLDN_MOUSE
θ value	0.125558 (rank : 24)	NC score	0.021841 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

SWP70_MOUSE
θ value	0.125558 (rank : 25)	NC score	0.088434 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	1097	Shared Neighborhood Hits	30
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CYH3_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.093986 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SWP70_HUMAN
θ value	0.163984 (rank : 27)	NC score	0.091327 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	973	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TCOF_MOUSE
θ value	0.163984 (rank : 28)	NC score	0.032383 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

DNL1_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.032800 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

EP400_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.015631 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	556	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

M3K11_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.001063 (rank : 125)
Query Neighborhood Hits	117	Target Neighborhood Hits	1136	Shared Neighborhood Hits	8
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PKNX2_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.020595 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

ANR47_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.026335 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CYH1_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.081514 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

SRRM2_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.017790 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TBC10_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.020336 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

CD22_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.010048 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	365	Shared Neighborhood Hits	3
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CYH1_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.081218 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

GP161_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.004193 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	690	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6U8, O75963, Q5TGK0, Q5TGK1	Gene names	GPR161
Domain Architecture
Description	Probable G-protein coupled receptor 161 (G-protein coupled receptor RE2).

PKD1_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.014180 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	387	Shared Neighborhood Hits	3
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PRPF3_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.050164 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.049822 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

TOM1_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.018973 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

LIPS_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.025751 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	314	Shared Neighborhood Hits	16
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MUTYH_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.026640 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

RFIP1_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.020202 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TBX3_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.009887 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

AATK_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.004575 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	1243	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

DSPP_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.025110 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FA13A_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.016684 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

TB182_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.025629 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	414	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TSKS_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.020756 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

ALKB5_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.030111 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6C2, Q9NXD6	Gene names	ALKBH5
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 5.

ARHG1_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.016146 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CYH3_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.077102 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	137	Shared Neighborhood Hits	18
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

NET2_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.006694 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PHC2_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.013816 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PML_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.015846 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

APBB3_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.013324 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

CIC_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.010072 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	742	Shared Neighborhood Hits	18
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PDE4D_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.006222 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

SYAC_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.013606 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

WASIP_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.014715 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BC11A_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.001713 (rank : 123)
Query Neighborhood Hits	117	Target Neighborhood Hits	745	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BC11A_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.002908 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	732	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

CYH2_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.075674 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.075677 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	171	Shared Neighborhood Hits	18
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

DNL1_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.026526 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DTBP1_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.015437 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

LZTS1_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.007596 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	532	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MEFV_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.004868 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MPP10_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.014525 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	251	Shared Neighborhood Hits	5
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

SIAL_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.022192 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P21815	Gene names	IBSP, BNSP
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

ZN580_HUMAN
θ value	3.0926 (rank : 74)	NC score	-0.000079 (rank : 127)
Query Neighborhood Hits	117	Target Neighborhood Hits	727	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UK33, Q9NPP7	Gene names	ZNF580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580 (LDL-induced EC protein).

AATK_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.003315 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	942	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ALKB5_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.026315 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TSG4, Q80US0, Q8BKB9, Q8BKC1	Gene names	Alkbh5, Abh5, Ofoxd
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 5.

ANR11_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.026025 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

AXN1_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.008446 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

CGRE1_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.013834 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CO4A1_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.005322 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	450	Shared Neighborhood Hits	15
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

ERN1_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.000134 (rank : 126)
Query Neighborhood Hits	117	Target Neighborhood Hits	823	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQY0, Q9D340	Gene names	Ern1, Ire1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

PKNX2_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.015165 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

PLPP_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.024708 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q96GD0, Q9UGY2	Gene names	PDXP, PLP, PLPP
Domain Architecture
Description	Pyridoxal phosphate phosphatase (EC 3.1.3.74) (PLP phosphatase).

PLPP_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.024763 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P60487	Gene names	Pdxp, Plp, Plpp
Domain Architecture
Description	Pyridoxal phosphate phosphatase (EC 3.1.3.74) (PLP phosphatase).

POGZ_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.001075 (rank : 124)
Query Neighborhood Hits	117	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

AF10_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.006818 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

B3A3_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.005311 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

CAC1E_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.003795 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CBX2_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.010055 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CSKI2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.019682 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	747	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT2NL_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.007176 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	902	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

IWS1_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.015902 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	1258	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MAP1A_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.008674 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	1626	Shared Neighborhood Hits	22
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NGEF_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.006841 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PAK4_MOUSE
θ value	5.27518 (rank : 95)	NC score	-0.001786 (rank : 129)
Query Neighborhood Hits	117	Target Neighborhood Hits	1098	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ZSWM3_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.011698 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFL8	Gene names	Zswim3
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 3.

AFAD_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.010418 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	689	Shared Neighborhood Hits	16
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ARI3A_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.010346 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

CIZ1_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.013586 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	359	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CN102_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.010172 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XC6, Q8R3D7, Q99LT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102 homolog.

DPOD3_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.011760 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ELF4_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.005211 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

K0586_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.010112 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

PARP3_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.009369 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

REPS1_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.020118 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS1_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.012196 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

TLX3_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.002530 (rank : 120)
Query Neighborhood Hits	117	Target Neighborhood Hits	403	Shared Neighborhood Hits	5
SwissProt Accessions	O43711, Q96AD3	Gene names	TLX3, HOX11L2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2).

TLX3_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.002391 (rank : 121)
Query Neighborhood Hits	117	Target Neighborhood Hits	346	Shared Neighborhood Hits	4
SwissProt Accessions	O55144	Gene names	Tlx3, Hox11l2, Rnx, Tlx1l2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein).

WDR24_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.004200 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

ZN142_HUMAN
θ value	6.88961 (rank : 110)	NC score	-0.000626 (rank : 128)
Query Neighborhood Hits	117	Target Neighborhood Hits	1007	Shared Neighborhood Hits	9
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

CT2NL_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.005223 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	1059	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DSPP_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.021835 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MLL2_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.006671 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	1788	Shared Neighborhood Hits	33
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MMP17_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.002007 (rank : 122)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

SYTL2_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.003629 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	253	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TENS4_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.007391 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

ZMYM3_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.006463 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

C43BP_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.240033 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.235574 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

MTMRD_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.052139 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA3_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.270914 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.277945 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.051072 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	556	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.073724 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.076132 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	96	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.069760 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.074478 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RHG25_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.053138 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	550	Shared Neighborhood Hits	25
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.055361 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	492	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

Hits sorted by NC score

OSBL5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
NC score	0.988950 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL8_HUMAN
NC score	0.943744 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	289	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB10_HUMAN
NC score	0.859911 (rank : 4)	θ value	2.25659e-51 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_MOUSE
NC score	0.835805 (rank : 5)	θ value	8.57503e-51 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
NC score	0.835616 (rank : 6)	θ value	2.94719e-51 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
NC score	0.832354 (rank : 7)	θ value	7.25919e-50 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	138	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL2_HUMAN
NC score	0.770066 (rank : 8)	θ value	3.50572e-28 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
NC score	0.767267 (rank : 9)	θ value	1.24688e-25 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL7_HUMAN
NC score	0.711323 (rank : 10)	θ value	1.02238e-19 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL6_HUMAN
NC score	0.704809 (rank : 11)	θ value	8.93572e-24 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
NC score	0.696496 (rank : 12)	θ value	1.5773e-20 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_MOUSE
NC score	0.696028 (rank : 13)	θ value	7.56453e-23 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBP2_HUMAN
NC score	0.692080 (rank : 14)	θ value	1.09232e-21 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	154	Shared Neighborhood Hits	32
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP1_HUMAN
NC score	0.688193 (rank : 15)	θ value	2.5182e-18 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	180	Shared Neighborhood Hits	30
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_MOUSE
NC score	0.683419 (rank : 16)	θ value	5.42112e-21 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	150	Shared Neighborhood Hits	28
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL3_HUMAN
NC score	0.682643 (rank : 17)	θ value	5.07402e-19 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL1_MOUSE
NC score	0.534861 (rank : 18)	θ value	9.8567e-31 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	336	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
NC score	0.522859 (rank : 19)	θ value	3.17079e-29 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.277945 (rank : 20)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	117	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.270914 (rank : 21)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	117	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.240033 (rank : 22)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.235574 (rank : 23)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CYH4_MOUSE
NC score	0.121505 (rank : 24)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	134	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.118600 (rank : 25)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH3_MOUSE
NC score	0.093986 (rank : 26)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SWP70_HUMAN
NC score	0.091327 (rank : 27)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	973	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.088434 (rank : 28)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	1097	Shared Neighborhood Hits	30
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CYH1_MOUSE
NC score	0.081514 (rank : 29)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
NC score	0.081218 (rank : 30)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_HUMAN
NC score	0.077102 (rank : 31)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	137	Shared Neighborhood Hits	18
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

PLEK2_MOUSE
NC score	0.076132 (rank : 32)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	117	Target Neighborhood Hits	96	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

CYH2_MOUSE
NC score	0.075677 (rank : 33)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	171	Shared Neighborhood Hits	18
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.075674 (rank : 34)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

PLEK_MOUSE
NC score	0.074478 (rank : 35)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	117	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK2_HUMAN
NC score	0.073724 (rank : 36)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
NC score	0.069760 (rank : 37)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

RHG25_MOUSE
NC score	0.055361 (rank : 38)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	117	Target Neighborhood Hits	492	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.053138 (rank : 39)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	117	Target Neighborhood Hits	550	Shared Neighborhood Hits	25
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MTMRD_HUMAN
NC score	0.052139 (rank : 40)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	117	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA6_HUMAN
NC score	0.051072 (rank : 41)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	117	Target Neighborhood Hits	556	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PRPF3_HUMAN
NC score	0.050164 (rank : 42)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
NC score	0.049822 (rank : 43)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

DNL1_MOUSE
NC score	0.032800 (rank : 44)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

TCOF_MOUSE
NC score	0.032383 (rank : 45)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ALKB5_HUMAN
NC score	0.030111 (rank : 46)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6C2, Q9NXD6	Gene names	ALKBH5
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 5.

MUTYH_MOUSE
NC score	0.026640 (rank : 47)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

DNL1_HUMAN
NC score	0.026526 (rank : 48)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

ANR47_HUMAN
NC score	0.026335 (rank : 49)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ALKB5_MOUSE
NC score	0.026315 (rank : 50)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TSG4, Q80US0, Q8BKB9, Q8BKC1	Gene names	Alkbh5, Abh5, Ofoxd
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 5.

ANR11_HUMAN
NC score	0.026025 (rank : 51)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

LIPS_HUMAN
NC score	0.025751 (rank : 52)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	314	Shared Neighborhood Hits	16
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

TB182_HUMAN
NC score	0.025629 (rank : 53)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	414	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

DSPP_MOUSE
NC score	0.025110 (rank : 54)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PLPP_MOUSE
NC score	0.024763 (rank : 55)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P60487	Gene names	Pdxp, Plp, Plpp
Domain Architecture
Description	Pyridoxal phosphate phosphatase (EC 3.1.3.74) (PLP phosphatase).

PLPP_HUMAN
NC score	0.024708 (rank : 56)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q96GD0, Q9UGY2	Gene names	PDXP, PLP, PLPP
Domain Architecture
Description	Pyridoxal phosphate phosphatase (EC 3.1.3.74) (PLP phosphatase).

SIAL_HUMAN
NC score	0.022192 (rank : 57)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P21815	Gene names	IBSP, BNSP
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

GLDN_MOUSE
NC score	0.021841 (rank : 58)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

DSPP_HUMAN
NC score	0.021835 (rank : 59)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TSKS_MOUSE
NC score	0.020756 (rank : 60)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

BRD2_HUMAN
NC score	0.020652 (rank : 61)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

PKNX2_HUMAN
NC score	0.020595 (rank : 62)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

TBC10_HUMAN
NC score	0.020336 (rank : 63)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

MYPN_MOUSE
NC score	0.020327 (rank : 64)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	421	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

RFIP1_MOUSE
NC score	0.020202 (rank : 65)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

REPS1_HUMAN
NC score	0.020118 (rank : 66)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

CSKI2_HUMAN
NC score	0.019682 (rank : 67)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	747	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TOM1_HUMAN
NC score	0.018973 (rank : 68)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

SRRM2_HUMAN
NC score	0.017790 (rank : 69)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

FA13A_HUMAN
NC score	0.016684 (rank : 70)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

ARHG1_MOUSE
NC score	0.016146 (rank : 71)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

IWS1_MOUSE
NC score	0.015902 (rank : 72)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	1258	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PML_HUMAN
NC score	0.015846 (rank : 73)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

EP400_HUMAN
NC score	0.015631 (rank : 74)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	556	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

DTBP1_MOUSE
NC score	0.015437 (rank : 75)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

PKNX2_MOUSE
NC score	0.015165 (rank : 76)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

WASIP_HUMAN
NC score	0.014715 (rank : 77)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MPP10_MOUSE
NC score	0.014525 (rank : 78)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	251	Shared Neighborhood Hits	5
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

PKD1_HUMAN
NC score	0.014180 (rank : 79)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	387	Shared Neighborhood Hits	3
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

CGRE1_HUMAN
NC score	0.013834 (rank : 80)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

PHC2_MOUSE
NC score	0.013816 (rank : 81)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

SYAC_MOUSE
NC score	0.013606 (rank : 82)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

CIZ1_HUMAN
NC score	0.013586 (rank : 83)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	359	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

APBB3_HUMAN
NC score	0.013324 (rank : 84)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

REPS1_MOUSE
NC score	0.012196 (rank : 85)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

DPOD3_HUMAN
NC score	0.011760 (rank : 86)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ZSWM3_MOUSE
NC score	0.011698 (rank : 87)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFL8	Gene names	Zswim3
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 3.

AFAD_HUMAN
NC score	0.010418 (rank : 88)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	689	Shared Neighborhood Hits	16
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ARI3A_HUMAN
NC score	0.010346 (rank : 89)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

CN102_MOUSE
NC score	0.010172 (rank : 90)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XC6, Q8R3D7, Q99LT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102 homolog.

K0586_HUMAN
NC score	0.010112 (rank : 91)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

CIC_MOUSE
NC score	0.010072 (rank : 92)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	742	Shared Neighborhood Hits	18
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CBX2_HUMAN
NC score	0.010055 (rank : 93)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CD22_HUMAN
NC score	0.010048 (rank : 94)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	365	Shared Neighborhood Hits	3
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

TBX3_MOUSE
NC score	0.009887 (rank : 95)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

PARP3_HUMAN
NC score	0.009369 (rank : 96)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

MAP1A_HUMAN
NC score	0.008674 (rank : 97)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	1626	Shared Neighborhood Hits	22
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

AXN1_MOUSE
NC score	0.008446 (rank : 98)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

LZTS1_HUMAN
NC score	0.007596 (rank : 99)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	532	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

TENS4_HUMAN
NC score	0.007391 (rank : 100)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

CT2NL_MOUSE
NC score	0.007176 (rank : 101)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	902	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NGEF_MOUSE
NC score	0.006841 (rank : 102)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

AF10_HUMAN
NC score	0.006818 (rank : 103)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

NET2_MOUSE
NC score	0.006694 (rank : 104)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

MLL2_HUMAN
NC score	0.006671 (rank : 105)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	1788	Shared Neighborhood Hits	33
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZMYM3_MOUSE
NC score	0.006463 (rank : 106)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

PDE4D_HUMAN
NC score	0.006222 (rank : 107)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

CO4A1_MOUSE
NC score	0.005322 (rank : 108)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	450	Shared Neighborhood Hits	15
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

B3A3_HUMAN
NC score	0.005311 (rank : 109)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

CT2NL_HUMAN
NC score	0.005223 (rank : 110)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	1059	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ELF4_HUMAN
NC score	0.005211 (rank : 111)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

MEFV_HUMAN
NC score	0.004868 (rank : 112)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

AATK_HUMAN
NC score	0.004575 (rank : 113)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	1243	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

WDR24_MOUSE
NC score	0.004200 (rank : 114)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

GP161_HUMAN
NC score	0.004193 (rank : 115)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	690	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6U8, O75963, Q5TGK0, Q5TGK1	Gene names	GPR161
Domain Architecture
Description	Probable G-protein coupled receptor 161 (G-protein coupled receptor RE2).

CAC1E_MOUSE
NC score	0.003795 (rank : 116)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SYTL2_MOUSE
NC score	0.003629 (rank : 117)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	253	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

AATK_MOUSE
NC score	0.003315 (rank : 118)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	942	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

BC11A_MOUSE
NC score	0.002908 (rank : 119)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	732	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

TLX3_HUMAN
NC score	0.002530 (rank : 120)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	403	Shared Neighborhood Hits	5
SwissProt Accessions	O43711, Q96AD3	Gene names	TLX3, HOX11L2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2).

TLX3_MOUSE
NC score	0.002391 (rank : 121)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	346	Shared Neighborhood Hits	4
SwissProt Accessions	O55144	Gene names	Tlx3, Hox11l2, Rnx, Tlx1l2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein).

MMP17_MOUSE
NC score	0.002007 (rank : 122)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

BC11A_HUMAN
NC score	0.001713 (rank : 123)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	745	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

POGZ_MOUSE
NC score	0.001075 (rank : 124)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

M3K11_HUMAN
NC score	0.001063 (rank : 125)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	1136	Shared Neighborhood Hits	8
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ERN1_MOUSE
NC score	0.000134 (rank : 126)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	823	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQY0, Q9D340	Gene names	Ern1, Ire1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE1 precursor (Inositol-requiring protein 1) (IRE1a) (Ire1-alpha) (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

ZN580_HUMAN
NC score	-0.000079 (rank : 127)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	727	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UK33, Q9NPP7	Gene names	ZNF580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580 (LDL-induced EC protein).

ZN142_HUMAN
NC score	-0.000626 (rank : 128)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	1007	Shared Neighborhood Hits	9
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

PAK4_MOUSE
NC score	-0.001786 (rank : 129)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	1098	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).