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Network neighborhood for query Sequence : CYH4_MOUSE

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CYH4_MOUSE
 
SwissProt Accessions Q80YW0 Gene names Pscd4
Domain
Architecture

No domain graphic available

Description Cytohesin-4.
Rank Plots



Hits sorted by θ


CYH4_HUMAN
 
θ value 0 (rank : 1) NC score 0.998812 (rank : 2)
Query Neighborhood Hits 134 Target Neighborhood Hits 135 Shared Neighborhood Hits 125
SwissProt Accessions Q9UIA0, Q5R3F9, Q9UGT6 Gene names PSCD4, CYT4
Domain
Architecture
Description Cytohesin-4.
CYH4_MOUSE
 
θ value 0 (rank : 2) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 134 Target Neighborhood Hits 134 Shared Neighborhood Hits 134
SwissProt Accessions Q80YW0 Gene names Pscd4
Domain
Architecture

No domain graphic available

Description Cytohesin-4.
CYH3_MOUSE
 
θ value 3.14709e-170 (rank : 3) NC score 0.991868 (rank : 3)
Query Neighborhood Hits 134 Target Neighborhood Hits 148 Shared Neighborhood Hits 122
SwissProt Accessions O08967, Q8CI93 Gene names Pscd3, Grp1
Domain
Architecture
Description Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).
CYH3_HUMAN
 
θ value 2.94559e-168 (rank : 4) NC score 0.989199 (rank : 4)
Query Neighborhood Hits 134 Target Neighborhood Hits 137 Shared Neighborhood Hits 112
SwissProt Accessions O43739 Gene names PSCD3, ARNO3, GRP1
Domain
Architecture
Description Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).
CYH1_HUMAN
 
θ value 5.74867e-164 (rank : 5) NC score 0.986326 (rank : 8)
Query Neighborhood Hits 134 Target Neighborhood Hits 184 Shared Neighborhood Hits 118
SwissProt Accessions Q15438, Q9P123, Q9P124 Gene names PSCD1, D17S811E
Domain
Architecture
Description Cytohesin-1 (SEC7 homolog B2-1).
CYH2_MOUSE
 
θ value 2.18449e-163 (rank : 6) NC score 0.988649 (rank : 5)
Query Neighborhood Hits 134 Target Neighborhood Hits 171 Shared Neighborhood Hits 117
SwissProt Accessions P63034, O89099, P97695, Q3UP39 Gene names Pscd2, Sec7b
Domain
Architecture

No domain graphic available

Description Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).
CYH1_MOUSE
 
θ value 6.35588e-163 (rank : 7) NC score 0.986446 (rank : 7)
Query Neighborhood Hits 134 Target Neighborhood Hits 176 Shared Neighborhood Hits 117
SwissProt Accessions Q9QX11, O88817 Gene names Pscd1
Domain
Architecture
Description Cytohesin-1 (CLM1).
CYH2_HUMAN
 
θ value 8.30107e-163 (rank : 8) NC score 0.988568 (rank : 6)
Query Neighborhood Hits 134 Target Neighborhood Hits 175 Shared Neighborhood Hits 117
SwissProt Accessions Q99418, Q92958 Gene names PSCD2, ARNO
Domain
Architecture
Description Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).
BIG1_HUMAN
 
θ value 1.28137e-46 (rank : 9) NC score 0.823648 (rank : 9)
Query Neighborhood Hits 134 Target Neighborhood Hits 76 Shared Neighborhood Hits 22
SwissProt Accessions Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0 Gene names ARFGEF1, ARFGEP1, BIG1
Domain
Architecture
Description Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).
BIG2_HUMAN
 
θ value 3.48949e-44 (rank : 10) NC score 0.819422 (rank : 10)
Query Neighborhood Hits 134 Target Neighborhood Hits 66 Shared Neighborhood Hits 23
SwissProt Accessions Q9Y6D5, Q5TFT9, Q9NTS1 Gene names ARFGEF2, ARFGEP2, BIG2
Domain
Architecture
Description Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).
IQEC1_HUMAN
 
θ value 1.73584e-35 (rank : 11) NC score 0.790726 (rank : 15)
Query Neighborhood Hits 134 Target Neighborhood Hits 76 Shared Neighborhood Hits 26
SwissProt Accessions Q6DN90, O94863, Q96D85 Gene names IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).
IQEC1_MOUSE
 
θ value 5.0505e-35 (rank : 12) NC score 0.791528 (rank : 13)
Query Neighborhood Hits 134 Target Neighborhood Hits 54 Shared Neighborhood Hits 24
SwissProt Accessions Q8R0S2, Q3TZC3, Q5DU15 Gene names Iqsec1, Kiaa0763
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 1.
GBF1_HUMAN
 
θ value 1.6247e-33 (rank : 13) NC score 0.810636 (rank : 11)
Query Neighborhood Hits 134 Target Neighborhood Hits 142 Shared Neighborhood Hits 23
SwissProt Accessions Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473 Gene names GBF1, KIAA0248
Domain
Architecture
Description Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).
IQEC3_MOUSE
 
θ value 2.12192e-33 (rank : 14) NC score 0.790897 (rank : 14)
Query Neighborhood Hits 134 Target Neighborhood Hits 274 Shared Neighborhood Hits 28
SwissProt Accessions Q3TES0, Q3UHP8, Q80TJ8 Gene names Iqsec3, Kiaa1110
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 3.
IQEC3_HUMAN
 
θ value 8.06329e-33 (rank : 15) NC score 0.799366 (rank : 12)
Query Neighborhood Hits 134 Target Neighborhood Hits 125 Shared Neighborhood Hits 29
SwissProt Accessions Q9UPP2, Q8TB43 Gene names IQSEC3, KIAA1110
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 3.
IQEC2_MOUSE
 
θ value 2.34606e-32 (rank : 16) NC score 0.743028 (rank : 19)
Query Neighborhood Hits 134 Target Neighborhood Hits 417 Shared Neighborhood Hits 28
SwissProt Accessions Q5DU25 Gene names Iqsec2, Kiaa0522
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 2.
IQEC2_HUMAN
 
θ value 4.00176e-32 (rank : 17) NC score 0.742730 (rank : 20)
Query Neighborhood Hits 134 Target Neighborhood Hits 403 Shared Neighborhood Hits 27
SwissProt Accessions Q5JU85, O60275 Gene names IQSEC2, KIAA0522
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 2.
PSD4_MOUSE
 
θ value 2.20094e-22 (rank : 18) NC score 0.720450 (rank : 21)
Query Neighborhood Hits 134 Target Neighborhood Hits 78 Shared Neighborhood Hits 31
SwissProt Accessions Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44 Gene names Psd4
Domain
Architecture

No domain graphic available

Description PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).
PSD4_HUMAN
 
θ value 3.17815e-21 (rank : 19) NC score 0.714060 (rank : 22)
Query Neighborhood Hits 134 Target Neighborhood Hits 178 Shared Neighborhood Hits 35
SwissProt Accessions Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4 Gene names PSD4, EFA6B, TIC
Domain
Architecture

No domain graphic available

Description PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).
PSD3_HUMAN
 
θ value 4.29542e-18 (rank : 20) NC score 0.763310 (rank : 16)
Query Neighborhood Hits 134 Target Neighborhood Hits 75 Shared Neighborhood Hits 42
SwissProt Accessions Q9NYI0, Q9Y2F1 Gene names PSD3, EFA6R, HCA67, KIAA0942
Domain
Architecture
Description PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).
FBX8_HUMAN
 
θ value 1.80466e-16 (rank : 21) NC score 0.751591 (rank : 18)
Query Neighborhood Hits 134 Target Neighborhood Hits 44 Shared Neighborhood Hits 22
SwissProt Accessions Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4 Gene names FBXO8, FBS, FBX8
Domain
Architecture
Description F-box only protein 8 (F-box/SEC7 protein FBS).
FBX8_MOUSE
 
θ value 2.35696e-16 (rank : 22) NC score 0.753708 (rank : 17)
Query Neighborhood Hits 134 Target Neighborhood Hits 45 Shared Neighborhood Hits 22
SwissProt Accessions Q9QZN3 Gene names Fbxo8, Fbx8
Domain
Architecture
Description F-box only protein 8.
PKHA6_HUMAN
 
θ value 7.59969e-07 (rank : 23) NC score 0.371524 (rank : 28)
Query Neighborhood Hits 134 Target Neighborhood Hits 556 Shared Neighborhood Hits 99
SwissProt Accessions Q9Y2H5 Gene names PLEKHA6, KIAA0969, PEPP3
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).
PLEK_MOUSE
 
θ value 1.29631e-06 (rank : 24) NC score 0.376837 (rank : 27)
Query Neighborhood Hits 134 Target Neighborhood Hits 109 Shared Neighborhood Hits 71
SwissProt Accessions Q9JHK5, Q9ERI9 Gene names Plek
Domain
Architecture
Description Pleckstrin.
SWP70_HUMAN
 
θ value 1.29631e-06 (rank : 25) NC score 0.196357 (rank : 47)
Query Neighborhood Hits 134 Target Neighborhood Hits 973 Shared Neighborhood Hits 88
SwissProt Accessions Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8 Gene names SWAP70, KIAA0640
Domain
Architecture

No domain graphic available

Description Switch-associated protein 70 (SWAP-70).
PKHA6_MOUSE
 
θ value 1.69304e-06 (rank : 26) NC score 0.360094 (rank : 29)
Query Neighborhood Hits 134 Target Neighborhood Hits 591 Shared Neighborhood Hits 98
SwissProt Accessions Q7TQG1, Q8K0J5 Gene names Plekha6, Pepp3
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).
PLEK_HUMAN
 
θ value 1.69304e-06 (rank : 27) NC score 0.378526 (rank : 26)
Query Neighborhood Hits 134 Target Neighborhood Hits 110 Shared Neighborhood Hits 79
SwissProt Accessions P08567, Q53SU8, Q6FGM8, Q8WV81 Gene names PLEK, P47
Domain
Architecture
Description Pleckstrin (Platelet p47 protein).
CNKR1_HUMAN
 
θ value 3.77169e-06 (rank : 28) NC score 0.398844 (rank : 23)
Query Neighborhood Hits 134 Target Neighborhood Hits 154 Shared Neighborhood Hits 59
SwissProt Accessions Q969H4, O95381 Gene names CNKSR1, CNK1
Domain
Architecture

No domain graphic available

Description Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).
DAPP1_MOUSE
 
θ value 4.92598e-06 (rank : 29) NC score 0.307589 (rank : 36)
Query Neighborhood Hits 134 Target Neighborhood Hits 225 Shared Neighborhood Hits 72
SwissProt Accessions Q9QXT1, Q9R178 Gene names Dapp1, Bam32
Domain
Architecture
Description Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).
SWP70_MOUSE
 
θ value 6.43352e-06 (rank : 30) NC score 0.181628 (rank : 48)
Query Neighborhood Hits 134 Target Neighborhood Hits 1097 Shared Neighborhood Hits 86
SwissProt Accessions Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0 Gene names Swap70, Kiaa0640
Domain
Architecture

No domain graphic available

Description Switch-associated protein 70 (SWAP-70).
DAPP1_HUMAN
 
θ value 8.40245e-06 (rank : 31) NC score 0.296682 (rank : 37)
Query Neighborhood Hits 134 Target Neighborhood Hits 227 Shared Neighborhood Hits 71
SwissProt Accessions Q9UN19, Q8TCK5, Q9UHF2 Gene names DAPP1, BAM32
Domain
Architecture
Description Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).
PKHA1_HUMAN
 
θ value 8.40245e-06 (rank : 32) NC score 0.380806 (rank : 24)
Query Neighborhood Hits 134 Target Neighborhood Hits 127 Shared Neighborhood Hits 75
SwissProt Accessions Q9HB21, Q9BVK0 Gene names PLEKHA1, TAPP1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).
PKHA1_MOUSE
 
θ value 8.40245e-06 (rank : 33) NC score 0.379761 (rank : 25)
Query Neighborhood Hits 134 Target Neighborhood Hits 120 Shared Neighborhood Hits 73
SwissProt Accessions Q8BUL6, Q8BK96, Q8BXU1, Q8VE13 Gene names Plekha1, Tapp1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).
RHG25_MOUSE
 
θ value 2.44474e-05 (rank : 34) NC score 0.222254 (rank : 44)
Query Neighborhood Hits 134 Target Neighborhood Hits 492 Shared Neighborhood Hits 89
SwissProt Accessions Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98 Gene names Arhgap25, Kiaa0053
Domain
Architecture
Description Rho-GTPase-activating protein 25.
CENB2_HUMAN
 
θ value 4.1701e-05 (rank : 35) NC score 0.169671 (rank : 50)
Query Neighborhood Hits 134 Target Neighborhood Hits 425 Shared Neighborhood Hits 59
SwissProt Accessions Q15057, Q9UQR3 Gene names CENTB2, KIAA0041
Domain
Architecture
Description Centaurin-beta 2 (Cnt-b2).
CENB5_HUMAN
 
θ value 4.1701e-05 (rank : 36) NC score 0.158444 (rank : 54)
Query Neighborhood Hits 134 Target Neighborhood Hits 395 Shared Neighborhood Hits 62
SwissProt Accessions Q96P50, Q9BSR9, Q9C0E7 Gene names CENTB5, KIAA1716
Domain
Architecture
Description Centaurin-beta 5 (Cnt-b5).
RHG25_HUMAN
 
θ value 5.44631e-05 (rank : 37) NC score 0.219547 (rank : 45)
Query Neighborhood Hits 134 Target Neighborhood Hits 550 Shared Neighborhood Hits 92
SwissProt Accessions P42331, Q8IXQ2 Gene names ARHGAP25, KIAA0053
Domain
Architecture
Description Rho-GTPase-activating protein 25.
GNRP_HUMAN
 
θ value 0.000158464 (rank : 38) NC score 0.162353 (rank : 53)
Query Neighborhood Hits 134 Target Neighborhood Hits 239 Shared Neighborhood Hits 54
SwissProt Accessions Q13972, Q16027 Gene names RASGRF1, CDC25
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).
PLEK2_HUMAN
 
θ value 0.00020696 (rank : 39) NC score 0.329141 (rank : 33)
Query Neighborhood Hits 134 Target Neighborhood Hits 101 Shared Neighborhood Hits 71
SwissProt Accessions Q9NYT0, Q96JT0 Gene names PLEK2
Domain
Architecture
Description Pleckstrin-2.
PLEK2_MOUSE
 
θ value 0.00020696 (rank : 40) NC score 0.329964 (rank : 32)
Query Neighborhood Hits 134 Target Neighborhood Hits 96 Shared Neighborhood Hits 70
SwissProt Accessions Q9WV52 Gene names Plek2
Domain
Architecture
Description Pleckstrin-2.
PKHA2_MOUSE
 
θ value 0.000270298 (rank : 41) NC score 0.339067 (rank : 30)
Query Neighborhood Hits 134 Target Neighborhood Hits 116 Shared Neighborhood Hits 74
SwissProt Accessions Q9ERS5, Q8BY29 Gene names Plekha2, Tapp2
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).
CNKR2_HUMAN
 
θ value 0.000461057 (rank : 42) NC score 0.259408 (rank : 42)
Query Neighborhood Hits 134 Target Neighborhood Hits 197 Shared Neighborhood Hits 62
SwissProt Accessions Q8WXI2, O94976, Q8WXI1 Gene names CNKSR2, CNK2, KIAA0902, KSR2
Domain
Architecture

No domain graphic available

Description Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).
CNKR2_MOUSE
 
θ value 0.000461057 (rank : 43) NC score 0.259650 (rank : 41)
Query Neighborhood Hits 134 Target Neighborhood Hits 197 Shared Neighborhood Hits 62
SwissProt Accessions Q80YA9, Q80TP2 Gene names Cnksr2, Kiaa0902
Domain
Architecture

No domain graphic available

Description Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).
GNRP_MOUSE
 
θ value 0.000602161 (rank : 44) NC score 0.157440 (rank : 56)
Query Neighborhood Hits 134 Target Neighborhood Hits 191 Shared Neighborhood Hits 51
SwissProt Accessions P27671 Gene names Rasgrf1, Cdc25, Grf1
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).
PKHA5_HUMAN
 
θ value 0.000602161 (rank : 45) NC score 0.286346 (rank : 38)
Query Neighborhood Hits 134 Target Neighborhood Hits 455 Shared Neighborhood Hits 84
SwissProt Accessions Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8 Gene names PLEKHA5, KIAA1686, PEPP2
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).
3BP2_HUMAN
 
θ value 0.000786445 (rank : 46) NC score 0.268063 (rank : 40)
Query Neighborhood Hits 134 Target Neighborhood Hits 296 Shared Neighborhood Hits 45
SwissProt Accessions P78314, O00500, O15373, P78315 Gene names SH3BP2, 3BP2
Domain
Architecture
Description SH3 domain-binding protein 2 (3BP-2).
ANLN_MOUSE
 
θ value 0.00102713 (rank : 47) NC score 0.202824 (rank : 46)
Query Neighborhood Hits 134 Target Neighborhood Hits 297 Shared Neighborhood Hits 27
SwissProt Accessions Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0 Gene names Anln
Domain
Architecture

No domain graphic available

Description Actin-binding protein anillin.
OSBP1_HUMAN
 
θ value 0.00102713 (rank : 48) NC score 0.158091 (rank : 55)
Query Neighborhood Hits 134 Target Neighborhood Hits 180 Shared Neighborhood Hits 66
SwissProt Accessions P22059 Gene names OSBP, OSBP1
Domain
Architecture
Description Oxysterol-binding protein 1.
PKHA4_MOUSE
 
θ value 0.00102713 (rank : 49) NC score 0.333063 (rank : 31)
Query Neighborhood Hits 134 Target Neighborhood Hits 202 Shared Neighborhood Hits 65
SwissProt Accessions Q8VC98, Q8R3N3 Gene names Plekha4, Pepp1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).
3BP2_MOUSE
 
θ value 0.00134147 (rank : 50) NC score 0.274777 (rank : 39)
Query Neighborhood Hits 134 Target Neighborhood Hits 142 Shared Neighborhood Hits 40
SwissProt Accessions Q06649 Gene names Sh3bp2, 3bp2
Domain
Architecture
Description SH3 domain-binding protein 2 (3BP-2).
ANLN_HUMAN
 
θ value 0.00134147 (rank : 51) NC score 0.236482 (rank : 43)
Query Neighborhood Hits 134 Target Neighborhood Hits 222 Shared Neighborhood Hits 28
SwissProt Accessions Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0 Gene names ANLN
Domain
Architecture

No domain graphic available

Description Actin-binding protein anillin.
PHLB1_MOUSE
 
θ value 0.00228821 (rank : 52) NC score 0.146541 (rank : 60)
Query Neighborhood Hits 134 Target Neighborhood Hits 678 Shared Neighborhood Hits 52
SwissProt Accessions Q6PDH0, Q80TV2 Gene names Phldb1, Kiaa0638, Ll5a
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).
MTMR5_HUMAN
 
θ value 0.00298849 (rank : 53) NC score 0.146838 (rank : 58)
Query Neighborhood Hits 134 Target Neighborhood Hits 141 Shared Neighborhood Hits 48
SwissProt Accessions O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8 Gene names SBF1, MTMR5
Domain
Architecture
Description SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).
MYO10_HUMAN
 
θ value 0.00298849 (rank : 54) NC score 0.095965 (rank : 89)
Query Neighborhood Hits 134 Target Neighborhood Hits 920 Shared Neighborhood Hits 83
SwissProt Accessions Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6 Gene names MYO10
Domain
Architecture
Description Myosin-10 (Myosin X).
OSBL8_HUMAN
 
θ value 0.00298849 (rank : 55) NC score 0.146595 (rank : 59)
Query Neighborhood Hits 134 Target Neighborhood Hits 289 Shared Neighborhood Hits 29
SwissProt Accessions Q9BZF1, Q8WXP8, Q9P277 Gene names OSBPL8, KIAA1451, ORP8, OSBP10
Domain
Architecture
Description Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).
PHLB2_MOUSE
 
θ value 0.00298849 (rank : 56) NC score 0.131079 (rank : 66)
Query Neighborhood Hits 134 Target Neighborhood Hits 1016 Shared Neighborhood Hits 55
SwissProt Accessions Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3 Gene names Phldb2, Ll5b
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).
PKHA4_HUMAN
 
θ value 0.00298849 (rank : 57) NC score 0.312497 (rank : 35)
Query Neighborhood Hits 134 Target Neighborhood Hits 283 Shared Neighborhood Hits 67
SwissProt Accessions Q9H4M7, Q8N4M8, Q8N658 Gene names PLEKHA4, PEPP1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).
PHLB2_HUMAN
 
θ value 0.00390308 (rank : 58) NC score 0.130666 (rank : 67)
Query Neighborhood Hits 134 Target Neighborhood Hits 964 Shared Neighborhood Hits 51
SwissProt Accessions Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5 Gene names PHLDB2, LL5B
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).
OSBP2_HUMAN
 
θ value 0.00869519 (rank : 59) NC score 0.127087 (rank : 71)
Query Neighborhood Hits 134 Target Neighborhood Hits 154 Shared Neighborhood Hits 57
SwissProt Accessions Q969R2, O60396, Q9BY96, Q9BZF0 Gene names OSBP2, KIAA1664, ORP4, OSBPL4
Domain
Architecture
Description Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).
PKHA2_HUMAN
 
θ value 0.0113563 (rank : 60) NC score 0.318837 (rank : 34)
Query Neighborhood Hits 134 Target Neighborhood Hits 119 Shared Neighborhood Hits 73
SwissProt Accessions Q9HB19 Gene names PLEKHA2, TAPP2
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).
OSBL5_HUMAN
 
θ value 0.0193708 (rank : 61) NC score 0.121505 (rank : 75)
Query Neighborhood Hits 134 Target Neighborhood Hits 117 Shared Neighborhood Hits 22
SwissProt Accessions Q9H0X9, Q9BZB0, Q9P1Z4 Gene names OSBPL5, KIAA1534, ORP5
Domain
Architecture
Description Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).
OSBL5_MOUSE
 
θ value 0.0193708 (rank : 62) NC score 0.124106 (rank : 73)
Query Neighborhood Hits 134 Target Neighborhood Hits 77 Shared Neighborhood Hits 24
SwissProt Accessions Q9ER64, Q8R510, Q99NF5 Gene names Osbpl5, Obph1, Osbp2
Domain
Architecture
Description Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).
PHLB1_HUMAN
 
θ value 0.0193708 (rank : 63) NC score 0.133158 (rank : 63)
Query Neighborhood Hits 134 Target Neighborhood Hits 1038 Shared Neighborhood Hits 54
SwissProt Accessions Q86UU1, O75133, Q4KMF8, Q8TEQ2 Gene names PHLDB1, DLNB07, KIAA0638, LL5A
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).
FGD6_MOUSE
 
θ value 0.0252991 (rank : 64) NC score 0.100195 (rank : 85)
Query Neighborhood Hits 134 Target Neighborhood Hits 282 Shared Neighborhood Hits 56
SwissProt Accessions Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7 Gene names Fgd6, Kiaa1362
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 6.
MTMRD_HUMAN
 
θ value 0.0252991 (rank : 65) NC score 0.127681 (rank : 70)
Query Neighborhood Hits 134 Target Neighborhood Hits 135 Shared Neighborhood Hits 60
SwissProt Accessions Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097 Gene names SBF2, CMT4B2, KIAA1766, MTMR13
Domain
Architecture

No domain graphic available

Description Myotubularin-related protein 13 (SET-binding factor 2).
CENB1_HUMAN
 
θ value 0.0330416 (rank : 66) NC score 0.128068 (rank : 69)
Query Neighborhood Hits 134 Target Neighborhood Hits 383 Shared Neighborhood Hits 52
SwissProt Accessions Q15027 Gene names CENTB1, KIAA0050
Domain
Architecture
Description Centaurin-beta 1 (Cnt-b1).
DYN2_HUMAN
 
θ value 0.0330416 (rank : 67) NC score 0.132628 (rank : 64)
Query Neighborhood Hits 134 Target Neighborhood Hits 112 Shared Neighborhood Hits 34
SwissProt Accessions P50570, Q7Z5S3, Q9UPH4 Gene names DNM2, DYN2
Domain
Architecture
Description Dynamin-2 (EC 3.6.5.5).
DYN2_MOUSE
 
θ value 0.0330416 (rank : 68) NC score 0.132623 (rank : 65)
Query Neighborhood Hits 134 Target Neighborhood Hits 104 Shared Neighborhood Hits 34
SwissProt Accessions P39054, Q9DBE1 Gene names Dnm2, Dyn2
Domain
Architecture
Description Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).
DYN3_HUMAN
 
θ value 0.0330416 (rank : 69) NC score 0.133188 (rank : 62)
Query Neighborhood Hits 134 Target Neighborhood Hits 158 Shared Neighborhood Hits 34
SwissProt Accessions Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6 Gene names DNM3, KIAA0820
Domain
Architecture
Description Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).
OSBL9_HUMAN
 
θ value 0.0330416 (rank : 70) NC score 0.134991 (rank : 61)
Query Neighborhood Hits 134 Target Neighborhood Hits 138 Shared Neighborhood Hits 59
SwissProt Accessions Q96SU4, Q9H9X2 Gene names OSBPL9, ORP9, OSBP4
Domain
Architecture
Description Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).
AKT1_HUMAN
 
θ value 0.0431538 (rank : 71) NC score 0.036235 (rank : 136)
Query Neighborhood Hits 134 Target Neighborhood Hits 885 Shared Neighborhood Hits 52
SwissProt Accessions P31749, Q9BWB6 Gene names AKT1, PKB, RAC
Domain
Architecture
Description RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).
AKT2_HUMAN
 
θ value 0.0431538 (rank : 72) NC score 0.039407 (rank : 133)
Query Neighborhood Hits 134 Target Neighborhood Hits 878 Shared Neighborhood Hits 47
SwissProt Accessions P31751, Q68GC0 Gene names AKT2
Domain
Architecture
Description RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).
AKT2_MOUSE
 
θ value 0.0431538 (rank : 73) NC score 0.039268 (rank : 134)
Query Neighborhood Hits 134 Target Neighborhood Hits 875 Shared Neighborhood Hits 44
SwissProt Accessions Q60823 Gene names Akt2
Domain
Architecture
Description RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).
AKT1_MOUSE
 
θ value 0.0563607 (rank : 74) NC score 0.035605 (rank : 137)
Query Neighborhood Hits 134 Target Neighborhood Hits 878 Shared Neighborhood Hits 51
SwissProt Accessions P31750, Q62274 Gene names Akt1, Akt, Rac
Domain
Architecture
Description RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).
FGD6_HUMAN
 
θ value 0.0736092 (rank : 75) NC score 0.102054 (rank : 83)
Query Neighborhood Hits 134 Target Neighborhood Hits 237 Shared Neighborhood Hits 55
SwissProt Accessions Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5 Gene names FGD6, KIAA1362, ZFYVE24
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).
AKT3_HUMAN
 
θ value 0.0961366 (rank : 76) NC score 0.031613 (rank : 138)
Query Neighborhood Hits 134 Target Neighborhood Hits 872 Shared Neighborhood Hits 40
SwissProt Accessions Q9Y243, Q96QV3, Q9UFP5 Gene names AKT3
Domain
Architecture
Description RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).
AKT3_MOUSE
 
θ value 0.0961366 (rank : 77) NC score 0.031607 (rank : 139)
Query Neighborhood Hits 134 Target Neighborhood Hits 872 Shared Neighborhood Hits 40
SwissProt Accessions Q9WUA6 Gene names Akt3
Domain
Architecture
Description RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).
OSB10_HUMAN
 
θ value 0.163984 (rank : 78) NC score 0.106465 (rank : 79)
Query Neighborhood Hits 134 Target Neighborhood Hits 55 Shared Neighborhood Hits 30
SwissProt Accessions Q9BXB5, Q9BTU5 Gene names OSBPL10, ORP10, OSBP9
Domain
Architecture
Description Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).
PKHF2_MOUSE
 
θ value 0.163984 (rank : 79) NC score 0.063626 (rank : 117)
Query Neighborhood Hits 134 Target Neighborhood Hits 77 Shared Neighborhood Hits 21
SwissProt Accessions Q91WB4 Gene names Plekhf2
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).
TARA_MOUSE
 
θ value 0.163984 (rank : 80) NC score 0.093190 (rank : 92)
Query Neighborhood Hits 134 Target Neighborhood Hits 1133 Shared Neighborhood Hits 66
SwissProt Accessions Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90 Gene names Triobp, Kiaa1662, Tara
Domain
Architecture

No domain graphic available

Description TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).
RASA1_HUMAN
 
θ value 0.21417 (rank : 81) NC score 0.176594 (rank : 49)
Query Neighborhood Hits 134 Target Neighborhood Hits 258 Shared Neighborhood Hits 53
SwissProt Accessions P20936 Gene names RASA1, RASA
Domain
Architecture
Description Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).
TARA_HUMAN
 
θ value 0.21417 (rank : 82) NC score 0.067605 (rank : 115)
Query Neighborhood Hits 134 Target Neighborhood Hits 1626 Shared Neighborhood Hits 66
SwissProt Accessions Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4 Gene names TRIOBP, KIAA1662, TARA
Domain
Architecture
Description TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).
TBCD2_HUMAN
 
θ value 0.21417 (rank : 83) NC score 0.116278 (rank : 76)
Query Neighborhood Hits 134 Target Neighborhood Hits 419 Shared Neighborhood Hits 36
SwissProt Accessions Q9BYX2 Gene names TBC1D2, PARIS1
Domain
Architecture
Description TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).
FGD4_HUMAN
 
θ value 0.279714 (rank : 84) NC score 0.085099 (rank : 101)
Query Neighborhood Hits 134 Target Neighborhood Hits 219 Shared Neighborhood Hits 46
SwissProt Accessions Q96M96, Q6ULS2, Q8TCP6 Gene names FGD4, FRABP, ZFYVE6
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).
OSB11_HUMAN
 
θ value 0.279714 (rank : 85) NC score 0.113169 (rank : 78)
Query Neighborhood Hits 134 Target Neighborhood Hits 60 Shared Neighborhood Hits 31
SwissProt Accessions Q9BXB4 Gene names OSBPL11, ORP11, OSBP12
Domain
Architecture
Description Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).
OSB11_MOUSE
 
θ value 0.279714 (rank : 86) NC score 0.113620 (rank : 77)
Query Neighborhood Hits 134 Target Neighborhood Hits 71 Shared Neighborhood Hits 33
SwissProt Accessions Q8CI95 Gene names Osbpl11
Domain
Architecture
Description Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).
PKHA3_MOUSE
 
θ value 0.279714 (rank : 87) NC score 0.129430 (rank : 68)
Query Neighborhood Hits 134 Target Neighborhood Hits 67 Shared Neighborhood Hits 47
SwissProt Accessions Q9ERS4 Gene names Plekha3, Fapp1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).
PKHB1_MOUSE
 
θ value 0.279714 (rank : 88) NC score 0.123453 (rank : 74)
Query Neighborhood Hits 134 Target Neighborhood Hits 47 Shared Neighborhood Hits 45
SwissProt Accessions Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3 Gene names Plekhb1, Phr1
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).
PKHF2_HUMAN
 
θ value 0.279714 (rank : 89) NC score 0.055330 (rank : 125)
Query Neighborhood Hits 134 Target Neighborhood Hits 75 Shared Neighborhood Hits 18
SwissProt Accessions Q9H8W4 Gene names PLEKHF2, ZFYVE18
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).
GRB7_HUMAN
 
θ value 0.365318 (rank : 90) NC score 0.073221 (rank : 110)
Query Neighborhood Hits 134 Target Neighborhood Hits 156 Shared Neighborhood Hits 24
SwissProt Accessions Q14451, Q92568, Q96DF9 Gene names GRB7
Domain
Architecture
Description Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).
PKHB1_HUMAN
 
θ value 0.365318 (rank : 91) NC score 0.153352 (rank : 57)
Query Neighborhood Hits 134 Target Neighborhood Hits 46 Shared Neighborhood Hits 45
SwissProt Accessions Q9UF11, Q9UBF5, Q9UI37, Q9UI44 Gene names PLEKHB1, KPL1, PHR1
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).
RASA3_HUMAN
 
θ value 0.365318 (rank : 92) NC score 0.098689 (rank : 86)
Query Neighborhood Hits 134 Target Neighborhood Hits 166 Shared Neighborhood Hits 42
SwissProt Accessions Q14644 Gene names RASA3
Domain
Architecture
Description Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).
FARP2_MOUSE
 
θ value 0.47712 (rank : 93) NC score 0.091029 (rank : 97)
Query Neighborhood Hits 134 Target Neighborhood Hits 209 Shared Neighborhood Hits 53
SwissProt Accessions Q91VS8, Q3TAP2, Q69ZZ0 Gene names Farp2, Kiaa0793
Domain
Architecture

No domain graphic available

Description FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).
OSBP2_MOUSE
 
θ value 0.47712 (rank : 94) NC score 0.095071 (rank : 90)
Query Neighborhood Hits 134 Target Neighborhood Hits 150 Shared Neighborhood Hits 49
SwissProt Accessions Q5QNQ6, Q8CF21 Gene names Osbp2
Domain
Architecture

No domain graphic available

Description Oxysterol-binding protein 2.
FARP2_HUMAN
 
θ value 0.62314 (rank : 95) NC score 0.082232 (rank : 103)
Query Neighborhood Hits 134 Target Neighborhood Hits 240 Shared Neighborhood Hits 45
SwissProt Accessions O94887, Q53QM5, Q8WU27, Q9UFE7 Gene names FARP2, KIAA0793
Domain
Architecture

No domain graphic available

Description FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).
FGD5_MOUSE
 
θ value 0.62314 (rank : 96) NC score 0.086533 (rank : 99)
Query Neighborhood Hits 134 Target Neighborhood Hits 170 Shared Neighborhood Hits 40
SwissProt Accessions Q80UZ0, Q8BHM5 Gene names Fgd5
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 5.
PKHB2_HUMAN
 
θ value 0.62314 (rank : 97) NC score 0.166545 (rank : 52)
Query Neighborhood Hits 134 Target Neighborhood Hits 54 Shared Neighborhood Hits 48
SwissProt Accessions Q96CS7, Q86W37, Q9BV75, Q9NWK1 Gene names PLEKHB2, EVT2
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 2 (Evectin-2).
PKHA3_HUMAN
 
θ value 0.813845 (rank : 98) NC score 0.126830 (rank : 72)
Query Neighborhood Hits 134 Target Neighborhood Hits 66 Shared Neighborhood Hits 45
SwissProt Accessions Q9HB20, Q86TQ1, Q9NXT3 Gene names PLEKHA3, FAPP1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).
FGD4_MOUSE
 
θ value 1.06291 (rank : 99) NC score 0.083384 (rank : 102)
Query Neighborhood Hits 134 Target Neighborhood Hits 227 Shared Neighborhood Hits 46
SwissProt Accessions Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4 Gene names Fgd4
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).
DYN1_HUMAN
 
θ value 1.38821 (rank : 100) NC score 0.105008 (rank : 82)
Query Neighborhood Hits 134 Target Neighborhood Hits 216 Shared Neighborhood Hits 29
SwissProt Accessions Q05193 Gene names DNM1, DNM
Domain
Architecture
Description Dynamin-1 (EC 3.6.5.5).
DYN1_MOUSE
 
θ value 1.38821 (rank : 101) NC score 0.105342 (rank : 80)
Query Neighborhood Hits 134 Target Neighborhood Hits 168 Shared Neighborhood Hits 28
SwissProt Accessions P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1 Gene names Dnm1, Dnm
Domain
Architecture
Description Dynamin-1 (EC 3.6.5.5).
FARP1_HUMAN
 
θ value 1.38821 (rank : 102) NC score 0.094980 (rank : 91)
Query Neighborhood Hits 134 Target Neighborhood Hits 241 Shared Neighborhood Hits 63
SwissProt Accessions Q9Y4F1, Q6IQ29 Gene names FARP1, CDEP
Domain
Architecture

No domain graphic available

Description FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).
FGD2_MOUSE
 
θ value 1.38821 (rank : 103) NC score 0.062935 (rank : 118)
Query Neighborhood Hits 134 Target Neighborhood Hits 163 Shared Neighborhood Hits 29
SwissProt Accessions Q8BY35, O88841, Q7TSE3, Q8VDH4 Gene names Fgd2
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 2.
PKHB2_MOUSE
 
θ value 1.38821 (rank : 104) NC score 0.167911 (rank : 51)
Query Neighborhood Hits 134 Target Neighborhood Hits 48 Shared Neighborhood Hits 46
SwissProt Accessions Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27 Gene names Plekhb2, Evt2
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 2 (Evectin-2).
AB1IP_HUMAN
 
θ value 1.81305 (rank : 105) NC score 0.085623 (rank : 100)
Query Neighborhood Hits 134 Target Neighborhood Hits 213 Shared Neighborhood Hits 24
SwissProt Accessions Q7Z5R6, Q8IWS8, Q8IZZ7 Gene names APBB1IP, PREL1, RARP1, RIAM
Domain
Architecture

No domain graphic available

Description Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).
FGD2_HUMAN
 
θ value 1.81305 (rank : 106) NC score 0.065606 (rank : 116)
Query Neighborhood Hits 134 Target Neighborhood Hits 151 Shared Neighborhood Hits 26
SwissProt Accessions Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2 Gene names FGD2, ZFYVE4
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).
GRB10_MOUSE
 
θ value 1.81305 (rank : 107) NC score 0.051856 (rank : 130)
Query Neighborhood Hits 134 Target Neighborhood Hits 156 Shared Neighborhood Hits 20
SwissProt Accessions Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5 Gene names Grb10
Domain
Architecture
Description Growth factor receptor-bound protein 10 (GRB10 adaptor protein).
LAMB1_HUMAN
 
θ value 1.81305 (rank : 108) NC score 0.005741 (rank : 150)
Query Neighborhood Hits 134 Target Neighborhood Hits 1018 Shared Neighborhood Hits 14
SwissProt Accessions P07942 Gene names LAMB1
Domain
Architecture
Description Laminin beta-1 chain precursor (Laminin B1 chain).
OSBL3_HUMAN
 
θ value 1.81305 (rank : 109) NC score 0.097130 (rank : 88)
Query Neighborhood Hits 134 Target Neighborhood Hits 93 Shared Neighborhood Hits 38
SwissProt Accessions Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6 Gene names OSBPL3, KIAA0704, ORP3
Domain
Architecture
Description Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).
RASA3_MOUSE
 
θ value 1.81305 (rank : 110) NC score 0.088702 (rank : 98)
Query Neighborhood Hits 134 Target Neighborhood Hits 144 Shared Neighborhood Hits 39
SwissProt Accessions Q60790 Gene names Rasa3
Domain
Architecture
Description Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).
AB1IP_MOUSE
 
θ value 2.36792 (rank : 111) NC score 0.068678 (rank : 114)
Query Neighborhood Hits 134 Target Neighborhood Hits 181 Shared Neighborhood Hits 26
SwissProt Accessions Q8R5A3, O35329, Q8BRU0, Q99KV8 Gene names Apbb1ip, Prel1
Domain
Architecture

No domain graphic available

Description Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).
BMX_HUMAN
 
θ value 2.36792 (rank : 112) NC score 0.014283 (rank : 144)
Query Neighborhood Hits 134 Target Neighborhood Hits 942 Shared Neighborhood Hits 48
SwissProt Accessions P51813, O60564, Q12871 Gene names BMX
Domain
Architecture
Description Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).
DGKH_HUMAN
 
θ value 2.36792 (rank : 113) NC score 0.092061 (rank : 94)
Query Neighborhood Hits 134 Target Neighborhood Hits 255 Shared Neighborhood Hits 64
SwissProt Accessions Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9 Gene names DGKH
Domain
Architecture

No domain graphic available

Description Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).
MRIP_MOUSE
 
θ value 2.36792 (rank : 114) NC score 0.092187 (rank : 93)
Query Neighborhood Hits 134 Target Neighborhood Hits 569 Shared Neighborhood Hits 67
SwissProt Accessions P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8 Gene names Mrip, Kiaa0864, Rhoip3
Domain
Architecture
Description Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).
OSBL3_MOUSE
 
θ value 2.36792 (rank : 115) NC score 0.091514 (rank : 96)
Query Neighborhood Hits 134 Target Neighborhood Hits 86 Shared Neighborhood Hits 38
SwissProt Accessions Q9DBS9 Gene names Osbpl3, Orp3
Domain
Architecture
Description Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).
BMX_MOUSE
 
θ value 3.0926 (rank : 116) NC score 0.012077 (rank : 145)
Query Neighborhood Hits 134 Target Neighborhood Hits 912 Shared Neighborhood Hits 45
SwissProt Accessions P97504 Gene names Bmx
Domain
Architecture

No domain graphic available

Description Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).
CENA1_HUMAN
 
θ value 3.0926 (rank : 117) NC score 0.100212 (rank : 84)
Query Neighborhood Hits 134 Target Neighborhood Hits 87 Shared Neighborhood Hits 45
SwissProt Accessions O75689 Gene names CENTA1
Domain
Architecture

No domain graphic available

Description Centaurin-alpha 1 (Putative MAPK-activating protein PM25).
CEND1_HUMAN
 
θ value 3.0926 (rank : 118) NC score 0.081183 (rank : 104)
Query Neighborhood Hits 134 Target Neighborhood Hits 284 Shared Neighborhood Hits 71
SwissProt Accessions Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4 Gene names CENTD1, ARAP2, KIAA0580
Domain
Architecture

No domain graphic available

Description Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).
LAMB1_MOUSE
 
θ value 3.0926 (rank : 119) NC score 0.005374 (rank : 151)
Query Neighborhood Hits 134 Target Neighborhood Hits 919 Shared Neighborhood Hits 12
SwissProt Accessions P02469 Gene names Lamb1-1, Lamb-1
Domain
Architecture
Description Laminin beta-1 chain precursor (Laminin B1 chain).
MYH9_HUMAN
 
θ value 3.0926 (rank : 120) NC score 0.011100 (rank : 148)
Query Neighborhood Hits 134 Target Neighborhood Hits 1762 Shared Neighborhood Hits 32
SwissProt Accessions P35579, O60805 Gene names MYH9
Domain
Architecture
Description Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).
MYH9_MOUSE
 
θ value 3.0926 (rank : 121) NC score 0.011601 (rank : 146)
Query Neighborhood Hits 134 Target Neighborhood Hits 1829 Shared Neighborhood Hits 36
SwissProt Accessions Q8VDD5 Gene names Myh9
Domain
Architecture

No domain graphic available

Description Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).
SMC2_MOUSE
 
θ value 3.0926 (rank : 122) NC score 0.008408 (rank : 149)
Query Neighborhood Hits 134 Target Neighborhood Hits 1131 Shared Neighborhood Hits 20
SwissProt Accessions Q8CG48, Q61076, Q9CS17, Q9CSD8 Gene names Smc2l1, Cape, Fin16, Smc2
Domain
Architecture
Description Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).
CAPS2_HUMAN
 
θ value 4.03905 (rank : 123) NC score 0.048301 (rank : 131)
Query Neighborhood Hits 134 Target Neighborhood Hits 81 Shared Neighborhood Hits 25
SwissProt Accessions Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8 Gene names CADPS2, CAPS2, KIAA1591
Domain
Architecture

No domain graphic available

Description Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).
CAPS2_MOUSE
 
θ value 4.03905 (rank : 124) NC score 0.041388 (rank : 132)
Query Neighborhood Hits 134 Target Neighborhood Hits 78 Shared Neighborhood Hits 25
SwissProt Accessions Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6 Gene names Cadps2, Caps2
Domain
Architecture

No domain graphic available

Description Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).
CEND3_HUMAN
 
θ value 4.03905 (rank : 125) NC score 0.069793 (rank : 113)
Query Neighborhood Hits 134 Target Neighborhood Hits 275 Shared Neighborhood Hits 41
SwissProt Accessions Q8WWN8 Gene names CENTD3, ARAP3
Domain
Architecture

No domain graphic available

Description Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).
GRB14_MOUSE
 
θ value 5.27518 (rank : 126) NC score 0.038703 (rank : 135)
Query Neighborhood Hits 134 Target Neighborhood Hits 149 Shared Neighborhood Hits 23
SwissProt Accessions Q9JLM9, Q3UI77, Q8VDI2, Q9CR03 Gene names Grb14
Domain
Architecture
Description Growth factor receptor-bound protein 14 (GRB14 adapter protein).
TEC_HUMAN
 
θ value 5.27518 (rank : 127) NC score 0.025054 (rank : 141)
Query Neighborhood Hits 134 Target Neighborhood Hits 1006 Shared Neighborhood Hits 32
SwissProt Accessions P42680 Gene names TEC, PSCTK4
Domain
Architecture
Description Tyrosine-protein kinase Tec (EC 2.7.10.2).
VASP_HUMAN
 
θ value 5.27518 (rank : 128) NC score 0.011158 (rank : 147)
Query Neighborhood Hits 134 Target Neighborhood Hits 201 Shared Neighborhood Hits 5
SwissProt Accessions P50552, Q6PIZ1, Q93035 Gene names VASP
Domain
Architecture
Description Vasodilator-stimulated phosphoprotein (VASP).
FGD3_MOUSE
 
θ value 6.88961 (rank : 129) NC score 0.058531 (rank : 121)
Query Neighborhood Hits 134 Target Neighborhood Hits 257 Shared Neighborhood Hits 31
SwissProt Accessions O88842, Q8BQ72 Gene names Fgd3
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 3.
MRIP_HUMAN
 
θ value 6.88961 (rank : 130) NC score 0.078478 (rank : 106)
Query Neighborhood Hits 134 Target Neighborhood Hits 578 Shared Neighborhood Hits 65
SwissProt Accessions Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40 Gene names MRIP, KIAA0864, RHOIP3
Domain
Architecture

No domain graphic available

Description Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).
RAPH1_HUMAN
 
θ value 6.88961 (rank : 131) NC score 0.026330 (rank : 140)
Query Neighborhood Hits 134 Target Neighborhood Hits 593 Shared Neighborhood Hits 22
SwissProt Accessions Q70E73, Q96Q37, Q9C0I2 Gene names RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain
Architecture

No domain graphic available

Description Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).
CEND3_MOUSE
 
θ value 8.99809 (rank : 132) NC score 0.062885 (rank : 119)
Query Neighborhood Hits 134 Target Neighborhood Hits 228 Shared Neighborhood Hits 39
SwissProt Accessions Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6 Gene names Centd3, Arap3, Drag1, Kiaa4097
Domain
Architecture

No domain graphic available

Description Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).
CENG1_HUMAN
 
θ value 8.99809 (rank : 133) NC score 0.020269 (rank : 143)
Query Neighborhood Hits 134 Target Neighborhood Hits 544 Shared Neighborhood Hits 18
SwissProt Accessions Q99490, O00578, Q548E0, Q8IWU3 Gene names CENTG1, AGAP2, KIAA0167
Domain
Architecture
Description Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).
CENG1_MOUSE
 
θ value 8.99809 (rank : 134) NC score 0.020669 (rank : 142)
Query Neighborhood Hits 134 Target Neighborhood Hits 531 Shared Neighborhood Hits 18
SwissProt Accessions Q3UHD9, Q5DU45 Gene names Centg1, Agap2, Kiaa0167
Domain
Architecture

No domain graphic available

Description Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).
C43BP_HUMAN
 
θ value θ > 10 (rank : 135) NC score 0.091873 (rank : 95)
Query Neighborhood Hits 134 Target Neighborhood Hits 87 Shared Neighborhood Hits 56
SwissProt Accessions Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8 Gene names COL4A3BP, STARD11
Domain
Architecture
Description Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).
C43BP_MOUSE
 
θ value θ > 10 (rank : 136) NC score 0.098193 (rank : 87)
Query Neighborhood Hits 134 Target Neighborhood Hits 91 Shared Neighborhood Hits 56
SwissProt Accessions Q9EQG9, Q91WB1, Q9CU52, Q9EQG8 Gene names Col4a3bp, Stard11
Domain
Architecture
Description Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).
CENA2_HUMAN
 
θ value θ > 10 (rank : 137) NC score 0.105294 (rank : 81)
Query Neighborhood Hits 134 Target Neighborhood Hits 83 Shared Neighborhood Hits 45
SwissProt Accessions Q9NPF8, Q8N4Q6, Q96SD5 Gene names CENTA2
Domain
Architecture
Description Centaurin-alpha 2.
CENA2_MOUSE
 
θ value θ > 10 (rank : 138) NC score 0.056835 (rank : 122)
Query Neighborhood Hits 134 Target Neighborhood Hits 68 Shared Neighborhood Hits 34
SwissProt Accessions Q8R2V5 Gene names Centa2
Domain
Architecture

No domain graphic available

Description Centaurin-alpha 2.
CEND1_MOUSE
 
θ value θ > 10 (rank : 139) NC score 0.054254 (rank : 126)
Query Neighborhood Hits 134 Target Neighborhood Hits 260 Shared Neighborhood Hits 53
SwissProt Accessions Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6 Gene names Centd1, Kiaa0580
Domain
Architecture

No domain graphic available

Description Centaurin-delta 1 (Cnt-d1).
CEND2_HUMAN
 
θ value θ > 10 (rank : 140) NC score 0.074495 (rank : 109)
Query Neighborhood Hits 134 Target Neighborhood Hits 166 Shared Neighborhood Hits 56
SwissProt Accessions Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71 Gene names CENTD2, ARAP1, KIAA0782
Domain
Architecture
Description Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).
FGD1_HUMAN
 
θ value θ > 10 (rank : 141) NC score 0.055714 (rank : 124)
Query Neighborhood Hits 134 Target Neighborhood Hits 367 Shared Neighborhood Hits 37
SwissProt Accessions P98174, Q8N4D9 Gene names FGD1, ZFYVE3
Domain
Architecture
Description FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).
FGD1_MOUSE
 
θ value θ > 10 (rank : 142) NC score 0.056309 (rank : 123)
Query Neighborhood Hits 134 Target Neighborhood Hits 387 Shared Neighborhood Hits 35
SwissProt Accessions P52734 Gene names Fgd1
Domain
Architecture
Description FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).
FGD5_HUMAN
 
θ value θ > 10 (rank : 143) NC score 0.078728 (rank : 105)
Query Neighborhood Hits 134 Target Neighborhood Hits 235 Shared Neighborhood Hits 45
SwissProt Accessions Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4 Gene names FGD5, ZFYVE23
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).
GAB1_HUMAN
 
θ value θ > 10 (rank : 144) NC score 0.076460 (rank : 107)
Query Neighborhood Hits 134 Target Neighborhood Hits 279 Shared Neighborhood Hits 45
SwissProt Accessions Q13480, Q4W5G2, Q6P1W2 Gene names GAB1
Domain
Architecture
Description GRB2-associated-binding protein 1 (GRB2-associated binder 1).
GAB1_MOUSE
 
θ value θ > 10 (rank : 145) NC score 0.070006 (rank : 112)
Query Neighborhood Hits 134 Target Neighborhood Hits 233 Shared Neighborhood Hits 44
SwissProt Accessions Q9QYY0, Q91VW7 Gene names Gab1
Domain
Architecture
Description GRB2-associated-binding protein 1 (GRB2-associated binder 1).
GAB2_HUMAN
 
θ value θ > 10 (rank : 146) NC score 0.075728 (rank : 108)
Query Neighborhood Hits 134 Target Neighborhood Hits 188 Shared Neighborhood Hits 48
SwissProt Accessions Q9UQC2, O60317 Gene names GAB2, KIAA0571
Domain
Architecture
Description GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).
GAB2_MOUSE
 
θ value θ > 10 (rank : 147) NC score 0.073190 (rank : 111)
Query Neighborhood Hits 134 Target Neighborhood Hits 220 Shared Neighborhood Hits 46
SwissProt Accessions Q9Z1S8, Q9R1X3 Gene names Gab2
Domain
Architecture
Description GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).
OSBL2_HUMAN
 
θ value θ > 10 (rank : 148) NC score 0.052739 (rank : 128)
Query Neighborhood Hits 134 Target Neighborhood Hits 23 Shared Neighborhood Hits 13
SwissProt Accessions Q9H1P3, Q9BZB1, Q9Y4B8 Gene names OSBPL2, KIAA0772, ORP2
Domain
Architecture
Description Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).
OSBL7_HUMAN
 
θ value θ > 10 (rank : 149) NC score 0.062056 (rank : 120)
Query Neighborhood Hits 134 Target Neighborhood Hits 71 Shared Neighborhood Hits 30
SwissProt Accessions Q9BZF2 Gene names OSBPL7, ORP7
Domain
Architecture
Description Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).
RASA2_HUMAN
 
θ value θ > 10 (rank : 150) NC score 0.052063 (rank : 129)
Query Neighborhood Hits 134 Target Neighborhood Hits 157 Shared Neighborhood Hits 31
SwissProt Accessions Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2 Gene names RASA2, GAP1M, RASGAP
Domain
Architecture
Description Ras GTPase-activating protein 2 (GAP1m).
RASA2_MOUSE
 
θ value θ > 10 (rank : 151) NC score 0.053106 (rank : 127)
Query Neighborhood Hits 134 Target Neighborhood Hits 159 Shared Neighborhood Hits 38
SwissProt Accessions P58069 Gene names Rasa2
Domain
Architecture
Description Ras GTPase-activating protein 2 (GAP1m).

Hits sorted by NC score


CYH4_MOUSE
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 2)
Query Neighborhood Hits 134 Target Neighborhood Hits 134 Shared Neighborhood Hits 134
SwissProt Accessions Q80YW0 Gene names Pscd4
Domain
Architecture

No domain graphic available

Description Cytohesin-4.
CYH4_HUMAN
 
NC score 0.998812 (rank : 2) θ value 0 (rank : 1)
Query Neighborhood Hits 134 Target Neighborhood Hits 135 Shared Neighborhood Hits 125
SwissProt Accessions Q9UIA0, Q5R3F9, Q9UGT6 Gene names PSCD4, CYT4
Domain
Architecture
Description Cytohesin-4.
CYH3_MOUSE
 
NC score 0.991868 (rank : 3) θ value 3.14709e-170 (rank : 3)
Query Neighborhood Hits 134 Target Neighborhood Hits 148 Shared Neighborhood Hits 122
SwissProt Accessions O08967, Q8CI93 Gene names Pscd3, Grp1
Domain
Architecture
Description Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).
CYH3_HUMAN
 
NC score 0.989199 (rank : 4) θ value 2.94559e-168 (rank : 4)
Query Neighborhood Hits 134 Target Neighborhood Hits 137 Shared Neighborhood Hits 112
SwissProt Accessions O43739 Gene names PSCD3, ARNO3, GRP1
Domain
Architecture
Description Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).
CYH2_MOUSE
 
NC score 0.988649 (rank : 5) θ value 2.18449e-163 (rank : 6)
Query Neighborhood Hits 134 Target Neighborhood Hits 171 Shared Neighborhood Hits 117
SwissProt Accessions P63034, O89099, P97695, Q3UP39 Gene names Pscd2, Sec7b
Domain
Architecture

No domain graphic available

Description Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).
CYH2_HUMAN
 
NC score 0.988568 (rank : 6) θ value 8.30107e-163 (rank : 8)
Query Neighborhood Hits 134 Target Neighborhood Hits 175 Shared Neighborhood Hits 117
SwissProt Accessions Q99418, Q92958 Gene names PSCD2, ARNO
Domain
Architecture
Description Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).
CYH1_MOUSE
 
NC score 0.986446 (rank : 7) θ value 6.35588e-163 (rank : 7)
Query Neighborhood Hits 134 Target Neighborhood Hits 176 Shared Neighborhood Hits 117
SwissProt Accessions Q9QX11, O88817 Gene names Pscd1
Domain
Architecture
Description Cytohesin-1 (CLM1).
CYH1_HUMAN
 
NC score 0.986326 (rank : 8) θ value 5.74867e-164 (rank : 5)
Query Neighborhood Hits 134 Target Neighborhood Hits 184 Shared Neighborhood Hits 118
SwissProt Accessions Q15438, Q9P123, Q9P124 Gene names PSCD1, D17S811E
Domain
Architecture
Description Cytohesin-1 (SEC7 homolog B2-1).
BIG1_HUMAN
 
NC score 0.823648 (rank : 9) θ value 1.28137e-46 (rank : 9)
Query Neighborhood Hits 134 Target Neighborhood Hits 76 Shared Neighborhood Hits 22
SwissProt Accessions Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0 Gene names ARFGEF1, ARFGEP1, BIG1
Domain
Architecture
Description Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).
BIG2_HUMAN
 
NC score 0.819422 (rank : 10) θ value 3.48949e-44 (rank : 10)
Query Neighborhood Hits 134 Target Neighborhood Hits 66 Shared Neighborhood Hits 23
SwissProt Accessions Q9Y6D5, Q5TFT9, Q9NTS1 Gene names ARFGEF2, ARFGEP2, BIG2
Domain
Architecture
Description Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).
GBF1_HUMAN
 
NC score 0.810636 (rank : 11) θ value 1.6247e-33 (rank : 13)
Query Neighborhood Hits 134 Target Neighborhood Hits 142 Shared Neighborhood Hits 23
SwissProt Accessions Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473 Gene names GBF1, KIAA0248
Domain
Architecture
Description Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).
IQEC3_HUMAN
 
NC score 0.799366 (rank : 12) θ value 8.06329e-33 (rank : 15)
Query Neighborhood Hits 134 Target Neighborhood Hits 125 Shared Neighborhood Hits 29
SwissProt Accessions Q9UPP2, Q8TB43 Gene names IQSEC3, KIAA1110
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 3.
IQEC1_MOUSE
 
NC score 0.791528 (rank : 13) θ value 5.0505e-35 (rank : 12)
Query Neighborhood Hits 134 Target Neighborhood Hits 54 Shared Neighborhood Hits 24
SwissProt Accessions Q8R0S2, Q3TZC3, Q5DU15 Gene names Iqsec1, Kiaa0763
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 1.
IQEC3_MOUSE
 
NC score 0.790897 (rank : 14) θ value 2.12192e-33 (rank : 14)
Query Neighborhood Hits 134 Target Neighborhood Hits 274 Shared Neighborhood Hits 28
SwissProt Accessions Q3TES0, Q3UHP8, Q80TJ8 Gene names Iqsec3, Kiaa1110
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 3.
IQEC1_HUMAN
 
NC score 0.790726 (rank : 15) θ value 1.73584e-35 (rank : 11)
Query Neighborhood Hits 134 Target Neighborhood Hits 76 Shared Neighborhood Hits 26
SwissProt Accessions Q6DN90, O94863, Q96D85 Gene names IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).
PSD3_HUMAN
 
NC score 0.763310 (rank : 16) θ value 4.29542e-18 (rank : 20)
Query Neighborhood Hits 134 Target Neighborhood Hits 75 Shared Neighborhood Hits 42
SwissProt Accessions Q9NYI0, Q9Y2F1 Gene names PSD3, EFA6R, HCA67, KIAA0942
Domain
Architecture
Description PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).
FBX8_MOUSE
 
NC score 0.753708 (rank : 17) θ value 2.35696e-16 (rank : 22)
Query Neighborhood Hits 134 Target Neighborhood Hits 45 Shared Neighborhood Hits 22
SwissProt Accessions Q9QZN3 Gene names Fbxo8, Fbx8
Domain
Architecture
Description F-box only protein 8.
FBX8_HUMAN
 
NC score 0.751591 (rank : 18) θ value 1.80466e-16 (rank : 21)
Query Neighborhood Hits 134 Target Neighborhood Hits 44 Shared Neighborhood Hits 22
SwissProt Accessions Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4 Gene names FBXO8, FBS, FBX8
Domain
Architecture
Description F-box only protein 8 (F-box/SEC7 protein FBS).
IQEC2_MOUSE
 
NC score 0.743028 (rank : 19) θ value 2.34606e-32 (rank : 16)
Query Neighborhood Hits 134 Target Neighborhood Hits 417 Shared Neighborhood Hits 28
SwissProt Accessions Q5DU25 Gene names Iqsec2, Kiaa0522
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 2.
IQEC2_HUMAN
 
NC score 0.742730 (rank : 20) θ value 4.00176e-32 (rank : 17)
Query Neighborhood Hits 134 Target Neighborhood Hits 403 Shared Neighborhood Hits 27
SwissProt Accessions Q5JU85, O60275 Gene names IQSEC2, KIAA0522
Domain
Architecture

No domain graphic available

Description IQ motif and Sec7 domain-containing protein 2.
PSD4_MOUSE
 
NC score 0.720450 (rank : 21) θ value 2.20094e-22 (rank : 18)
Query Neighborhood Hits 134 Target Neighborhood Hits 78 Shared Neighborhood Hits 31
SwissProt Accessions Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44 Gene names Psd4
Domain
Architecture

No domain graphic available

Description PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).
PSD4_HUMAN
 
NC score 0.714060 (rank : 22) θ value 3.17815e-21 (rank : 19)
Query Neighborhood Hits 134 Target Neighborhood Hits 178 Shared Neighborhood Hits 35
SwissProt Accessions Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4 Gene names PSD4, EFA6B, TIC
Domain
Architecture

No domain graphic available

Description PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).
CNKR1_HUMAN
 
NC score 0.398844 (rank : 23) θ value 3.77169e-06 (rank : 28)
Query Neighborhood Hits 134 Target Neighborhood Hits 154 Shared Neighborhood Hits 59
SwissProt Accessions Q969H4, O95381 Gene names CNKSR1, CNK1
Domain
Architecture

No domain graphic available

Description Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).
PKHA1_HUMAN
 
NC score 0.380806 (rank : 24) θ value 8.40245e-06 (rank : 32)
Query Neighborhood Hits 134 Target Neighborhood Hits 127 Shared Neighborhood Hits 75
SwissProt Accessions Q9HB21, Q9BVK0 Gene names PLEKHA1, TAPP1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).
PKHA1_MOUSE
 
NC score 0.379761 (rank : 25) θ value 8.40245e-06 (rank : 33)
Query Neighborhood Hits 134 Target Neighborhood Hits 120 Shared Neighborhood Hits 73
SwissProt Accessions Q8BUL6, Q8BK96, Q8BXU1, Q8VE13 Gene names Plekha1, Tapp1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).
PLEK_HUMAN
 
NC score 0.378526 (rank : 26) θ value 1.69304e-06 (rank : 27)
Query Neighborhood Hits 134 Target Neighborhood Hits 110 Shared Neighborhood Hits 79
SwissProt Accessions P08567, Q53SU8, Q6FGM8, Q8WV81 Gene names PLEK, P47
Domain
Architecture
Description Pleckstrin (Platelet p47 protein).
PLEK_MOUSE
 
NC score 0.376837 (rank : 27) θ value 1.29631e-06 (rank : 24)
Query Neighborhood Hits 134 Target Neighborhood Hits 109 Shared Neighborhood Hits 71
SwissProt Accessions Q9JHK5, Q9ERI9 Gene names Plek
Domain
Architecture
Description Pleckstrin.
PKHA6_HUMAN
 
NC score 0.371524 (rank : 28) θ value 7.59969e-07 (rank : 23)
Query Neighborhood Hits 134 Target Neighborhood Hits 556 Shared Neighborhood Hits 99
SwissProt Accessions Q9Y2H5 Gene names PLEKHA6, KIAA0969, PEPP3
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).
PKHA6_MOUSE
 
NC score 0.360094 (rank : 29) θ value 1.69304e-06 (rank : 26)
Query Neighborhood Hits 134 Target Neighborhood Hits 591 Shared Neighborhood Hits 98
SwissProt Accessions Q7TQG1, Q8K0J5 Gene names Plekha6, Pepp3
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).
PKHA2_MOUSE
 
NC score 0.339067 (rank : 30) θ value 0.000270298 (rank : 41)
Query Neighborhood Hits 134 Target Neighborhood Hits 116 Shared Neighborhood Hits 74
SwissProt Accessions Q9ERS5, Q8BY29 Gene names Plekha2, Tapp2
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).
PKHA4_MOUSE
 
NC score 0.333063 (rank : 31) θ value 0.00102713 (rank : 49)
Query Neighborhood Hits 134 Target Neighborhood Hits 202 Shared Neighborhood Hits 65
SwissProt Accessions Q8VC98, Q8R3N3 Gene names Plekha4, Pepp1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).
PLEK2_MOUSE
 
NC score 0.329964 (rank : 32) θ value 0.00020696 (rank : 40)
Query Neighborhood Hits 134 Target Neighborhood Hits 96 Shared Neighborhood Hits 70
SwissProt Accessions Q9WV52 Gene names Plek2
Domain
Architecture
Description Pleckstrin-2.
PLEK2_HUMAN
 
NC score 0.329141 (rank : 33) θ value 0.00020696 (rank : 39)
Query Neighborhood Hits 134 Target Neighborhood Hits 101 Shared Neighborhood Hits 71
SwissProt Accessions Q9NYT0, Q96JT0 Gene names PLEK2
Domain
Architecture
Description Pleckstrin-2.
PKHA2_HUMAN
 
NC score 0.318837 (rank : 34) θ value 0.0113563 (rank : 60)
Query Neighborhood Hits 134 Target Neighborhood Hits 119 Shared Neighborhood Hits 73
SwissProt Accessions Q9HB19 Gene names PLEKHA2, TAPP2
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).
PKHA4_HUMAN
 
NC score 0.312497 (rank : 35) θ value 0.00298849 (rank : 57)
Query Neighborhood Hits 134 Target Neighborhood Hits 283 Shared Neighborhood Hits 67
SwissProt Accessions Q9H4M7, Q8N4M8, Q8N658 Gene names PLEKHA4, PEPP1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).
DAPP1_MOUSE
 
NC score 0.307589 (rank : 36) θ value 4.92598e-06 (rank : 29)
Query Neighborhood Hits 134 Target Neighborhood Hits 225 Shared Neighborhood Hits 72
SwissProt Accessions Q9QXT1, Q9R178 Gene names Dapp1, Bam32
Domain
Architecture
Description Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).
DAPP1_HUMAN
 
NC score 0.296682 (rank : 37) θ value 8.40245e-06 (rank : 31)
Query Neighborhood Hits 134 Target Neighborhood Hits 227 Shared Neighborhood Hits 71
SwissProt Accessions Q9UN19, Q8TCK5, Q9UHF2 Gene names DAPP1, BAM32
Domain
Architecture
Description Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).
PKHA5_HUMAN
 
NC score 0.286346 (rank : 38) θ value 0.000602161 (rank : 45)
Query Neighborhood Hits 134 Target Neighborhood Hits 455 Shared Neighborhood Hits 84
SwissProt Accessions Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8 Gene names PLEKHA5, KIAA1686, PEPP2
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).
3BP2_MOUSE
 
NC score 0.274777 (rank : 39) θ value 0.00134147 (rank : 50)
Query Neighborhood Hits 134 Target Neighborhood Hits 142 Shared Neighborhood Hits 40
SwissProt Accessions Q06649 Gene names Sh3bp2, 3bp2
Domain
Architecture
Description SH3 domain-binding protein 2 (3BP-2).
3BP2_HUMAN
 
NC score 0.268063 (rank : 40) θ value 0.000786445 (rank : 46)
Query Neighborhood Hits 134 Target Neighborhood Hits 296 Shared Neighborhood Hits 45
SwissProt Accessions P78314, O00500, O15373, P78315 Gene names SH3BP2, 3BP2
Domain
Architecture
Description SH3 domain-binding protein 2 (3BP-2).
CNKR2_MOUSE
 
NC score 0.259650 (rank : 41) θ value 0.000461057 (rank : 43)
Query Neighborhood Hits 134 Target Neighborhood Hits 197 Shared Neighborhood Hits 62
SwissProt Accessions Q80YA9, Q80TP2 Gene names Cnksr2, Kiaa0902
Domain
Architecture

No domain graphic available

Description Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).
CNKR2_HUMAN
 
NC score 0.259408 (rank : 42) θ value 0.000461057 (rank : 42)
Query Neighborhood Hits 134 Target Neighborhood Hits 197 Shared Neighborhood Hits 62
SwissProt Accessions Q8WXI2, O94976, Q8WXI1 Gene names CNKSR2, CNK2, KIAA0902, KSR2
Domain
Architecture

No domain graphic available

Description Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).
ANLN_HUMAN
 
NC score 0.236482 (rank : 43) θ value 0.00134147 (rank : 51)
Query Neighborhood Hits 134 Target Neighborhood Hits 222 Shared Neighborhood Hits 28
SwissProt Accessions Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0 Gene names ANLN
Domain
Architecture

No domain graphic available

Description Actin-binding protein anillin.
RHG25_MOUSE
 
NC score 0.222254 (rank : 44) θ value 2.44474e-05 (rank : 34)
Query Neighborhood Hits 134 Target Neighborhood Hits 492 Shared Neighborhood Hits 89
SwissProt Accessions Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98 Gene names Arhgap25, Kiaa0053
Domain
Architecture
Description Rho-GTPase-activating protein 25.
RHG25_HUMAN
 
NC score 0.219547 (rank : 45) θ value 5.44631e-05 (rank : 37)
Query Neighborhood Hits 134 Target Neighborhood Hits 550 Shared Neighborhood Hits 92
SwissProt Accessions P42331, Q8IXQ2 Gene names ARHGAP25, KIAA0053
Domain
Architecture
Description Rho-GTPase-activating protein 25.
ANLN_MOUSE
 
NC score 0.202824 (rank : 46) θ value 0.00102713 (rank : 47)
Query Neighborhood Hits 134 Target Neighborhood Hits 297 Shared Neighborhood Hits 27
SwissProt Accessions Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0 Gene names Anln
Domain
Architecture

No domain graphic available

Description Actin-binding protein anillin.
SWP70_HUMAN
 
NC score 0.196357 (rank : 47) θ value 1.29631e-06 (rank : 25)
Query Neighborhood Hits 134 Target Neighborhood Hits 973 Shared Neighborhood Hits 88
SwissProt Accessions Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8 Gene names SWAP70, KIAA0640
Domain
Architecture

No domain graphic available

Description Switch-associated protein 70 (SWAP-70).
SWP70_MOUSE
 
NC score 0.181628 (rank : 48) θ value 6.43352e-06 (rank : 30)
Query Neighborhood Hits 134 Target Neighborhood Hits 1097 Shared Neighborhood Hits 86
SwissProt Accessions Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0 Gene names Swap70, Kiaa0640
Domain
Architecture

No domain graphic available

Description Switch-associated protein 70 (SWAP-70).
RASA1_HUMAN
 
NC score 0.176594 (rank : 49) θ value 0.21417 (rank : 81)
Query Neighborhood Hits 134 Target Neighborhood Hits 258 Shared Neighborhood Hits 53
SwissProt Accessions P20936 Gene names RASA1, RASA
Domain
Architecture
Description Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).
CENB2_HUMAN
 
NC score 0.169671 (rank : 50) θ value 4.1701e-05 (rank : 35)
Query Neighborhood Hits 134 Target Neighborhood Hits 425 Shared Neighborhood Hits 59
SwissProt Accessions Q15057, Q9UQR3 Gene names CENTB2, KIAA0041
Domain
Architecture
Description Centaurin-beta 2 (Cnt-b2).
PKHB2_MOUSE
 
NC score 0.167911 (rank : 51) θ value 1.38821 (rank : 104)
Query Neighborhood Hits 134 Target Neighborhood Hits 48 Shared Neighborhood Hits 46
SwissProt Accessions Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27 Gene names Plekhb2, Evt2
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 2 (Evectin-2).
PKHB2_HUMAN
 
NC score 0.166545 (rank : 52) θ value 0.62314 (rank : 97)
Query Neighborhood Hits 134 Target Neighborhood Hits 54 Shared Neighborhood Hits 48
SwissProt Accessions Q96CS7, Q86W37, Q9BV75, Q9NWK1 Gene names PLEKHB2, EVT2
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 2 (Evectin-2).
GNRP_HUMAN
 
NC score 0.162353 (rank : 53) θ value 0.000158464 (rank : 38)
Query Neighborhood Hits 134 Target Neighborhood Hits 239 Shared Neighborhood Hits 54
SwissProt Accessions Q13972, Q16027 Gene names RASGRF1, CDC25
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).
CENB5_HUMAN
 
NC score 0.158444 (rank : 54) θ value 4.1701e-05 (rank : 36)
Query Neighborhood Hits 134 Target Neighborhood Hits 395 Shared Neighborhood Hits 62
SwissProt Accessions Q96P50, Q9BSR9, Q9C0E7 Gene names CENTB5, KIAA1716
Domain
Architecture
Description Centaurin-beta 5 (Cnt-b5).
OSBP1_HUMAN
 
NC score 0.158091 (rank : 55) θ value 0.00102713 (rank : 48)
Query Neighborhood Hits 134 Target Neighborhood Hits 180 Shared Neighborhood Hits 66
SwissProt Accessions P22059 Gene names OSBP, OSBP1
Domain
Architecture
Description Oxysterol-binding protein 1.
GNRP_MOUSE
 
NC score 0.157440 (rank : 56) θ value 0.000602161 (rank : 44)
Query Neighborhood Hits 134 Target Neighborhood Hits 191 Shared Neighborhood Hits 51
SwissProt Accessions P27671 Gene names Rasgrf1, Cdc25, Grf1
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).
PKHB1_HUMAN
 
NC score 0.153352 (rank : 57) θ value 0.365318 (rank : 91)
Query Neighborhood Hits 134 Target Neighborhood Hits 46 Shared Neighborhood Hits 45
SwissProt Accessions Q9UF11, Q9UBF5, Q9UI37, Q9UI44 Gene names PLEKHB1, KPL1, PHR1
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).
MTMR5_HUMAN
 
NC score 0.146838 (rank : 58) θ value 0.00298849 (rank : 53)
Query Neighborhood Hits 134 Target Neighborhood Hits 141 Shared Neighborhood Hits 48
SwissProt Accessions O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8 Gene names SBF1, MTMR5
Domain
Architecture
Description SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).
OSBL8_HUMAN
 
NC score 0.146595 (rank : 59) θ value 0.00298849 (rank : 55)
Query Neighborhood Hits 134 Target Neighborhood Hits 289 Shared Neighborhood Hits 29
SwissProt Accessions Q9BZF1, Q8WXP8, Q9P277 Gene names OSBPL8, KIAA1451, ORP8, OSBP10
Domain
Architecture
Description Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).
PHLB1_MOUSE
 
NC score 0.146541 (rank : 60) θ value 0.00228821 (rank : 52)
Query Neighborhood Hits 134 Target Neighborhood Hits 678 Shared Neighborhood Hits 52
SwissProt Accessions Q6PDH0, Q80TV2 Gene names Phldb1, Kiaa0638, Ll5a
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).
OSBL9_HUMAN
 
NC score 0.134991 (rank : 61) θ value 0.0330416 (rank : 70)
Query Neighborhood Hits 134 Target Neighborhood Hits 138 Shared Neighborhood Hits 59
SwissProt Accessions Q96SU4, Q9H9X2 Gene names OSBPL9, ORP9, OSBP4
Domain
Architecture
Description Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).
DYN3_HUMAN
 
NC score 0.133188 (rank : 62) θ value 0.0330416 (rank : 69)
Query Neighborhood Hits 134 Target Neighborhood Hits 158 Shared Neighborhood Hits 34
SwissProt Accessions Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6 Gene names DNM3, KIAA0820
Domain
Architecture
Description Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).
PHLB1_HUMAN
 
NC score 0.133158 (rank : 63) θ value 0.0193708 (rank : 63)
Query Neighborhood Hits 134 Target Neighborhood Hits 1038 Shared Neighborhood Hits 54
SwissProt Accessions Q86UU1, O75133, Q4KMF8, Q8TEQ2 Gene names PHLDB1, DLNB07, KIAA0638, LL5A
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).
DYN2_HUMAN
 
NC score 0.132628 (rank : 64) θ value 0.0330416 (rank : 67)
Query Neighborhood Hits 134 Target Neighborhood Hits 112 Shared Neighborhood Hits 34
SwissProt Accessions P50570, Q7Z5S3, Q9UPH4 Gene names DNM2, DYN2
Domain
Architecture
Description Dynamin-2 (EC 3.6.5.5).
DYN2_MOUSE
 
NC score 0.132623 (rank : 65) θ value 0.0330416 (rank : 68)
Query Neighborhood Hits 134 Target Neighborhood Hits 104 Shared Neighborhood Hits 34
SwissProt Accessions P39054, Q9DBE1 Gene names Dnm2, Dyn2
Domain
Architecture
Description Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).
PHLB2_MOUSE
 
NC score 0.131079 (rank : 66) θ value 0.00298849 (rank : 56)
Query Neighborhood Hits 134 Target Neighborhood Hits 1016 Shared Neighborhood Hits 55
SwissProt Accessions Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3 Gene names Phldb2, Ll5b
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).
PHLB2_HUMAN
 
NC score 0.130666 (rank : 67) θ value 0.00390308 (rank : 58)
Query Neighborhood Hits 134 Target Neighborhood Hits 964 Shared Neighborhood Hits 51
SwissProt Accessions Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5 Gene names PHLDB2, LL5B
Domain
Architecture

No domain graphic available

Description Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).
PKHA3_MOUSE
 
NC score 0.129430 (rank : 68) θ value 0.279714 (rank : 87)
Query Neighborhood Hits 134 Target Neighborhood Hits 67 Shared Neighborhood Hits 47
SwissProt Accessions Q9ERS4 Gene names Plekha3, Fapp1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).
CENB1_HUMAN
 
NC score 0.128068 (rank : 69) θ value 0.0330416 (rank : 66)
Query Neighborhood Hits 134 Target Neighborhood Hits 383 Shared Neighborhood Hits 52
SwissProt Accessions Q15027 Gene names CENTB1, KIAA0050
Domain
Architecture
Description Centaurin-beta 1 (Cnt-b1).
MTMRD_HUMAN
 
NC score 0.127681 (rank : 70) θ value 0.0252991 (rank : 65)
Query Neighborhood Hits 134 Target Neighborhood Hits 135 Shared Neighborhood Hits 60
SwissProt Accessions Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097 Gene names SBF2, CMT4B2, KIAA1766, MTMR13
Domain
Architecture

No domain graphic available

Description Myotubularin-related protein 13 (SET-binding factor 2).
OSBP2_HUMAN
 
NC score 0.127087 (rank : 71) θ value 0.00869519 (rank : 59)
Query Neighborhood Hits 134 Target Neighborhood Hits 154 Shared Neighborhood Hits 57
SwissProt Accessions Q969R2, O60396, Q9BY96, Q9BZF0 Gene names OSBP2, KIAA1664, ORP4, OSBPL4
Domain
Architecture
Description Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).
PKHA3_HUMAN
 
NC score 0.126830 (rank : 72) θ value 0.813845 (rank : 98)
Query Neighborhood Hits 134 Target Neighborhood Hits 66 Shared Neighborhood Hits 45
SwissProt Accessions Q9HB20, Q86TQ1, Q9NXT3 Gene names PLEKHA3, FAPP1
Domain
Architecture
Description Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).
OSBL5_MOUSE
 
NC score 0.124106 (rank : 73) θ value 0.0193708 (rank : 62)
Query Neighborhood Hits 134 Target Neighborhood Hits 77 Shared Neighborhood Hits 24
SwissProt Accessions Q9ER64, Q8R510, Q99NF5 Gene names Osbpl5, Obph1, Osbp2
Domain
Architecture
Description Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).
PKHB1_MOUSE
 
NC score 0.123453 (rank : 74) θ value 0.279714 (rank : 88)
Query Neighborhood Hits 134 Target Neighborhood Hits 47 Shared Neighborhood Hits 45
SwissProt Accessions Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3 Gene names Plekhb1, Phr1
Domain
Architecture
Description Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).
OSBL5_HUMAN
 
NC score 0.121505 (rank : 75) θ value 0.0193708 (rank : 61)
Query Neighborhood Hits 134 Target Neighborhood Hits 117 Shared Neighborhood Hits 22
SwissProt Accessions Q9H0X9, Q9BZB0, Q9P1Z4 Gene names OSBPL5, KIAA1534, ORP5
Domain
Architecture
Description Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).
TBCD2_HUMAN
 
NC score 0.116278 (rank : 76) θ value 0.21417 (rank : 83)
Query Neighborhood Hits 134 Target Neighborhood Hits 419 Shared Neighborhood Hits 36
SwissProt Accessions Q9BYX2 Gene names TBC1D2, PARIS1
Domain
Architecture
Description TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).
OSB11_MOUSE
 
NC score 0.113620 (rank : 77) θ value 0.279714 (rank : 86)
Query Neighborhood Hits 134 Target Neighborhood Hits 71 Shared Neighborhood Hits 33
SwissProt Accessions Q8CI95 Gene names Osbpl11
Domain
Architecture
Description Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).
OSB11_HUMAN
 
NC score 0.113169 (rank : 78) θ value 0.279714 (rank : 85)
Query Neighborhood Hits 134 Target Neighborhood Hits 60 Shared Neighborhood Hits 31
SwissProt Accessions Q9BXB4 Gene names OSBPL11, ORP11, OSBP12
Domain
Architecture
Description Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).
OSB10_HUMAN
 
NC score 0.106465 (rank : 79) θ value 0.163984 (rank : 78)
Query Neighborhood Hits 134 Target Neighborhood Hits 55 Shared Neighborhood Hits 30
SwissProt Accessions Q9BXB5, Q9BTU5 Gene names OSBPL10, ORP10, OSBP9
Domain
Architecture
Description Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).
DYN1_MOUSE
 
NC score 0.105342 (rank : 80) θ value 1.38821 (rank : 101)
Query Neighborhood Hits 134 Target Neighborhood Hits 168 Shared Neighborhood Hits 28
SwissProt Accessions P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1 Gene names Dnm1, Dnm
Domain
Architecture
Description Dynamin-1 (EC 3.6.5.5).
CENA2_HUMAN
 
NC score 0.105294 (rank : 81) θ value θ > 10 (rank : 137)
Query Neighborhood Hits 134 Target Neighborhood Hits 83 Shared Neighborhood Hits 45
SwissProt Accessions Q9NPF8, Q8N4Q6, Q96SD5 Gene names CENTA2
Domain
Architecture
Description Centaurin-alpha 2.
DYN1_HUMAN
 
NC score 0.105008 (rank : 82) θ value 1.38821 (rank : 100)
Query Neighborhood Hits 134 Target Neighborhood Hits 216 Shared Neighborhood Hits 29
SwissProt Accessions Q05193 Gene names DNM1, DNM
Domain
Architecture
Description Dynamin-1 (EC 3.6.5.5).
FGD6_HUMAN
 
NC score 0.102054 (rank : 83) θ value 0.0736092 (rank : 75)
Query Neighborhood Hits 134 Target Neighborhood Hits 237 Shared Neighborhood Hits 55
SwissProt Accessions Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5 Gene names FGD6, KIAA1362, ZFYVE24
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).
CENA1_HUMAN
 
NC score 0.100212 (rank : 84) θ value 3.0926 (rank : 117)
Query Neighborhood Hits 134 Target Neighborhood Hits 87 Shared Neighborhood Hits 45
SwissProt Accessions O75689 Gene names CENTA1
Domain
Architecture

No domain graphic available

Description Centaurin-alpha 1 (Putative MAPK-activating protein PM25).
FGD6_MOUSE
 
NC score 0.100195 (rank : 85) θ value 0.0252991 (rank : 64)
Query Neighborhood Hits 134 Target Neighborhood Hits 282 Shared Neighborhood Hits 56
SwissProt Accessions Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7 Gene names Fgd6, Kiaa1362
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 6.
RASA3_HUMAN
 
NC score 0.098689 (rank : 86) θ value 0.365318 (rank : 92)
Query Neighborhood Hits 134 Target Neighborhood Hits 166 Shared Neighborhood Hits 42
SwissProt Accessions Q14644 Gene names RASA3
Domain
Architecture
Description Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).
C43BP_MOUSE
 
NC score 0.098193 (rank : 87) θ value θ > 10 (rank : 136)
Query Neighborhood Hits 134 Target Neighborhood Hits 91 Shared Neighborhood Hits 56
SwissProt Accessions Q9EQG9, Q91WB1, Q9CU52, Q9EQG8 Gene names Col4a3bp, Stard11
Domain
Architecture
Description Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).
OSBL3_HUMAN
 
NC score 0.097130 (rank : 88) θ value 1.81305 (rank : 109)
Query Neighborhood Hits 134 Target Neighborhood Hits 93 Shared Neighborhood Hits 38
SwissProt Accessions Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6 Gene names OSBPL3, KIAA0704, ORP3
Domain
Architecture
Description Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).
MYO10_HUMAN
 
NC score 0.095965 (rank : 89) θ value 0.00298849 (rank : 54)
Query Neighborhood Hits 134 Target Neighborhood Hits 920 Shared Neighborhood Hits 83
SwissProt Accessions Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6 Gene names MYO10
Domain
Architecture
Description Myosin-10 (Myosin X).
OSBP2_MOUSE
 
NC score 0.095071 (rank : 90) θ value 0.47712 (rank : 94)
Query Neighborhood Hits 134 Target Neighborhood Hits 150 Shared Neighborhood Hits 49
SwissProt Accessions Q5QNQ6, Q8CF21 Gene names Osbp2
Domain
Architecture

No domain graphic available

Description Oxysterol-binding protein 2.
FARP1_HUMAN
 
NC score 0.094980 (rank : 91) θ value 1.38821 (rank : 102)
Query Neighborhood Hits 134 Target Neighborhood Hits 241 Shared Neighborhood Hits 63
SwissProt Accessions Q9Y4F1, Q6IQ29 Gene names FARP1, CDEP
Domain
Architecture

No domain graphic available

Description FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).
TARA_MOUSE
 
NC score 0.093190 (rank : 92) θ value 0.163984 (rank : 80)
Query Neighborhood Hits 134 Target Neighborhood Hits 1133 Shared Neighborhood Hits 66
SwissProt Accessions Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90 Gene names Triobp, Kiaa1662, Tara
Domain
Architecture

No domain graphic available

Description TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).
MRIP_MOUSE
 
NC score 0.092187 (rank : 93) θ value 2.36792 (rank : 114)
Query Neighborhood Hits 134 Target Neighborhood Hits 569 Shared Neighborhood Hits 67
SwissProt Accessions P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8 Gene names Mrip, Kiaa0864, Rhoip3
Domain
Architecture
Description Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).
DGKH_HUMAN
 
NC score 0.092061 (rank : 94) θ value 2.36792 (rank : 113)
Query Neighborhood Hits 134 Target Neighborhood Hits 255 Shared Neighborhood Hits 64
SwissProt Accessions Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9 Gene names DGKH
Domain
Architecture

No domain graphic available

Description Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).
C43BP_HUMAN
 
NC score 0.091873 (rank : 95) θ value θ > 10 (rank : 135)
Query Neighborhood Hits 134 Target Neighborhood Hits 87 Shared Neighborhood Hits 56
SwissProt Accessions Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8 Gene names COL4A3BP, STARD11
Domain
Architecture
Description Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).
OSBL3_MOUSE
 
NC score 0.091514 (rank : 96) θ value 2.36792 (rank : 115)
Query Neighborhood Hits 134 Target Neighborhood Hits 86 Shared Neighborhood Hits 38
SwissProt Accessions Q9DBS9 Gene names Osbpl3, Orp3
Domain
Architecture
Description Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).
FARP2_MOUSE
 
NC score 0.091029 (rank : 97) θ value 0.47712 (rank : 93)
Query Neighborhood Hits 134 Target Neighborhood Hits 209 Shared Neighborhood Hits 53
SwissProt Accessions Q91VS8, Q3TAP2, Q69ZZ0 Gene names Farp2, Kiaa0793
Domain
Architecture

No domain graphic available

Description FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).
RASA3_MOUSE
 
NC score 0.088702 (rank : 98) θ value 1.81305 (rank : 110)
Query Neighborhood Hits 134 Target Neighborhood Hits 144 Shared Neighborhood Hits 39
SwissProt Accessions Q60790 Gene names Rasa3
Domain
Architecture
Description Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).
FGD5_MOUSE
 
NC score 0.086533 (rank : 99) θ value 0.62314 (rank : 96)
Query Neighborhood Hits 134 Target Neighborhood Hits 170 Shared Neighborhood Hits 40
SwissProt Accessions Q80UZ0, Q8BHM5 Gene names Fgd5
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 5.
AB1IP_HUMAN
 
NC score 0.085623 (rank : 100) θ value 1.81305 (rank : 105)
Query Neighborhood Hits 134 Target Neighborhood Hits 213 Shared Neighborhood Hits 24
SwissProt Accessions Q7Z5R6, Q8IWS8, Q8IZZ7 Gene names APBB1IP, PREL1, RARP1, RIAM
Domain
Architecture

No domain graphic available

Description Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).
FGD4_HUMAN
 
NC score 0.085099 (rank : 101) θ value 0.279714 (rank : 84)
Query Neighborhood Hits 134 Target Neighborhood Hits 219 Shared Neighborhood Hits 46
SwissProt Accessions Q96M96, Q6ULS2, Q8TCP6 Gene names FGD4, FRABP, ZFYVE6
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).
FGD4_MOUSE
 
NC score 0.083384 (rank : 102) θ value 1.06291 (rank : 99)
Query Neighborhood Hits 134 Target Neighborhood Hits 227 Shared Neighborhood Hits 46
SwissProt Accessions Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4 Gene names Fgd4
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).
FARP2_HUMAN
 
NC score 0.082232 (rank : 103) θ value 0.62314 (rank : 95)
Query Neighborhood Hits 134 Target Neighborhood Hits 240 Shared Neighborhood Hits 45
SwissProt Accessions O94887, Q53QM5, Q8WU27, Q9UFE7 Gene names FARP2, KIAA0793
Domain
Architecture

No domain graphic available

Description FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).
CEND1_HUMAN
 
NC score 0.081183 (rank : 104) θ value 3.0926 (rank : 118)
Query Neighborhood Hits 134 Target Neighborhood Hits 284 Shared Neighborhood Hits 71
SwissProt Accessions Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4 Gene names CENTD1, ARAP2, KIAA0580
Domain
Architecture

No domain graphic available

Description Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).
FGD5_HUMAN
 
NC score 0.078728 (rank : 105) θ value θ > 10 (rank : 143)
Query Neighborhood Hits 134 Target Neighborhood Hits 235 Shared Neighborhood Hits 45
SwissProt Accessions Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4 Gene names FGD5, ZFYVE23
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).
MRIP_HUMAN
 
NC score 0.078478 (rank : 106) θ value 6.88961 (rank : 130)
Query Neighborhood Hits 134 Target Neighborhood Hits 578 Shared Neighborhood Hits 65
SwissProt Accessions Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40 Gene names MRIP, KIAA0864, RHOIP3
Domain
Architecture

No domain graphic available

Description Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).
GAB1_HUMAN
 
NC score 0.076460 (rank : 107) θ value θ > 10 (rank : 144)
Query Neighborhood Hits 134 Target Neighborhood Hits 279 Shared Neighborhood Hits 45
SwissProt Accessions Q13480, Q4W5G2, Q6P1W2 Gene names GAB1
Domain
Architecture
Description GRB2-associated-binding protein 1 (GRB2-associated binder 1).
GAB2_HUMAN
 
NC score 0.075728 (rank : 108) θ value θ > 10 (rank : 146)
Query Neighborhood Hits 134 Target Neighborhood Hits 188 Shared Neighborhood Hits 48
SwissProt Accessions Q9UQC2, O60317 Gene names GAB2, KIAA0571
Domain
Architecture
Description GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).
CEND2_HUMAN
 
NC score 0.074495 (rank : 109) θ value θ > 10 (rank : 140)
Query Neighborhood Hits 134 Target Neighborhood Hits 166 Shared Neighborhood Hits 56
SwissProt Accessions Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71 Gene names CENTD2, ARAP1, KIAA0782
Domain
Architecture
Description Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).
GRB7_HUMAN
 
NC score 0.073221 (rank : 110) θ value 0.365318 (rank : 90)
Query Neighborhood Hits 134 Target Neighborhood Hits 156 Shared Neighborhood Hits 24
SwissProt Accessions Q14451, Q92568, Q96DF9 Gene names GRB7
Domain
Architecture
Description Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).
GAB2_MOUSE
 
NC score 0.073190 (rank : 111) θ value θ > 10 (rank : 147)
Query Neighborhood Hits 134 Target Neighborhood Hits 220 Shared Neighborhood Hits 46
SwissProt Accessions Q9Z1S8, Q9R1X3 Gene names Gab2
Domain
Architecture
Description GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).
GAB1_MOUSE
 
NC score 0.070006 (rank : 112) θ value θ > 10 (rank : 145)
Query Neighborhood Hits 134 Target Neighborhood Hits 233 Shared Neighborhood Hits 44
SwissProt Accessions Q9QYY0, Q91VW7 Gene names Gab1
Domain
Architecture
Description GRB2-associated-binding protein 1 (GRB2-associated binder 1).
CEND3_HUMAN
 
NC score 0.069793 (rank : 113) θ value 4.03905 (rank : 125)
Query Neighborhood Hits 134 Target Neighborhood Hits 275 Shared Neighborhood Hits 41
SwissProt Accessions Q8WWN8 Gene names CENTD3, ARAP3
Domain
Architecture

No domain graphic available

Description Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).
AB1IP_MOUSE
 
NC score 0.068678 (rank : 114) θ value 2.36792 (rank : 111)
Query Neighborhood Hits 134 Target Neighborhood Hits 181 Shared Neighborhood Hits 26
SwissProt Accessions Q8R5A3, O35329, Q8BRU0, Q99KV8 Gene names Apbb1ip, Prel1
Domain
Architecture

No domain graphic available

Description Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).
TARA_HUMAN
 
NC score 0.067605 (rank : 115) θ value 0.21417 (rank : 82)
Query Neighborhood Hits 134 Target Neighborhood Hits 1626 Shared Neighborhood Hits 66
SwissProt Accessions Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4 Gene names TRIOBP, KIAA1662, TARA
Domain
Architecture
Description TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).
FGD2_HUMAN
 
NC score 0.065606 (rank : 116) θ value 1.81305 (rank : 106)
Query Neighborhood Hits 134 Target Neighborhood Hits 151 Shared Neighborhood Hits 26
SwissProt Accessions Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2 Gene names FGD2, ZFYVE4
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).
PKHF2_MOUSE
 
NC score 0.063626 (rank : 117) θ value 0.163984 (rank : 79)
Query Neighborhood Hits 134 Target Neighborhood Hits 77 Shared Neighborhood Hits 21
SwissProt Accessions Q91WB4 Gene names Plekhf2
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).
FGD2_MOUSE
 
NC score 0.062935 (rank : 118) θ value 1.38821 (rank : 103)
Query Neighborhood Hits 134 Target Neighborhood Hits 163 Shared Neighborhood Hits 29
SwissProt Accessions Q8BY35, O88841, Q7TSE3, Q8VDH4 Gene names Fgd2
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 2.
CEND3_MOUSE
 
NC score 0.062885 (rank : 119) θ value 8.99809 (rank : 132)
Query Neighborhood Hits 134 Target Neighborhood Hits 228 Shared Neighborhood Hits 39
SwissProt Accessions Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6 Gene names Centd3, Arap3, Drag1, Kiaa4097
Domain
Architecture

No domain graphic available

Description Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).
OSBL7_HUMAN
 
NC score 0.062056 (rank : 120) θ value θ > 10 (rank : 149)
Query Neighborhood Hits 134 Target Neighborhood Hits 71 Shared Neighborhood Hits 30
SwissProt Accessions Q9BZF2 Gene names OSBPL7, ORP7
Domain
Architecture
Description Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).
FGD3_MOUSE
 
NC score 0.058531 (rank : 121) θ value 6.88961 (rank : 129)
Query Neighborhood Hits 134 Target Neighborhood Hits 257 Shared Neighborhood Hits 31
SwissProt Accessions O88842, Q8BQ72 Gene names Fgd3
Domain
Architecture

No domain graphic available

Description FYVE, RhoGEF and PH domain-containing protein 3.
CENA2_MOUSE
 
NC score 0.056835 (rank : 122) θ value θ > 10 (rank : 138)
Query Neighborhood Hits 134 Target Neighborhood Hits 68 Shared Neighborhood Hits 34
SwissProt Accessions Q8R2V5 Gene names Centa2
Domain
Architecture

No domain graphic available

Description Centaurin-alpha 2.
FGD1_MOUSE
 
NC score 0.056309 (rank : 123) θ value θ > 10 (rank : 142)
Query Neighborhood Hits 134 Target Neighborhood Hits 387 Shared Neighborhood Hits 35
SwissProt Accessions P52734 Gene names Fgd1
Domain
Architecture
Description FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).
FGD1_HUMAN
 
NC score 0.055714 (rank : 124) θ value θ > 10 (rank : 141)
Query Neighborhood Hits 134 Target Neighborhood Hits 367 Shared Neighborhood Hits 37
SwissProt Accessions P98174, Q8N4D9 Gene names FGD1, ZFYVE3
Domain
Architecture
Description FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).
PKHF2_HUMAN
 
NC score 0.055330 (rank : 125) θ value 0.279714 (rank : 89)
Query Neighborhood Hits 134 Target Neighborhood Hits 75 Shared Neighborhood Hits 18
SwissProt Accessions Q9H8W4 Gene names PLEKHF2, ZFYVE18
Domain
Architecture

No domain graphic available

Description Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).
CEND1_MOUSE
 
NC score 0.054254 (rank : 126) θ value θ > 10 (rank : 139)
Query Neighborhood Hits 134 Target Neighborhood Hits 260 Shared Neighborhood Hits 53
SwissProt Accessions Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6 Gene names Centd1, Kiaa0580
Domain
Architecture

No domain graphic available

Description Centaurin-delta 1 (Cnt-d1).
RASA2_MOUSE
 
NC score 0.053106 (rank : 127) θ value θ > 10 (rank : 151)
Query Neighborhood Hits 134 Target Neighborhood Hits 159 Shared Neighborhood Hits 38
SwissProt Accessions P58069 Gene names Rasa2
Domain
Architecture
Description Ras GTPase-activating protein 2 (GAP1m).
OSBL2_HUMAN
 
NC score 0.052739 (rank : 128) θ value θ > 10 (rank : 148)
Query Neighborhood Hits 134 Target Neighborhood Hits 23 Shared Neighborhood Hits 13
SwissProt Accessions Q9H1P3, Q9BZB1, Q9Y4B8 Gene names OSBPL2, KIAA0772, ORP2
Domain
Architecture
Description Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).
RASA2_HUMAN
 
NC score 0.052063 (rank : 129) θ value θ > 10 (rank : 150)
Query Neighborhood Hits 134 Target Neighborhood Hits 157 Shared Neighborhood Hits 31
SwissProt Accessions Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2 Gene names RASA2, GAP1M, RASGAP
Domain
Architecture
Description Ras GTPase-activating protein 2 (GAP1m).
GRB10_MOUSE
 
NC score 0.051856 (rank : 130) θ value 1.81305 (rank : 107)
Query Neighborhood Hits 134 Target Neighborhood Hits 156 Shared Neighborhood Hits 20
SwissProt Accessions Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5 Gene names Grb10
Domain
Architecture
Description Growth factor receptor-bound protein 10 (GRB10 adaptor protein).
CAPS2_HUMAN
 
NC score 0.048301 (rank : 131) θ value 4.03905 (rank : 123)
Query Neighborhood Hits 134 Target Neighborhood Hits 81 Shared Neighborhood Hits 25
SwissProt Accessions Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8 Gene names CADPS2, CAPS2, KIAA1591
Domain
Architecture

No domain graphic available

Description Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).
CAPS2_MOUSE
 
NC score 0.041388 (rank : 132) θ value 4.03905 (rank : 124)
Query Neighborhood Hits 134 Target Neighborhood Hits 78 Shared Neighborhood Hits 25
SwissProt Accessions Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6 Gene names Cadps2, Caps2
Domain
Architecture

No domain graphic available

Description Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).
AKT2_HUMAN
 
NC score 0.039407 (rank : 133) θ value 0.0431538 (rank : 72)
Query Neighborhood Hits 134 Target Neighborhood Hits 878 Shared Neighborhood Hits 47
SwissProt Accessions P31751, Q68GC0 Gene names AKT2
Domain
Architecture
Description RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).
AKT2_MOUSE
 
NC score 0.039268 (rank : 134) θ value 0.0431538 (rank : 73)
Query Neighborhood Hits 134 Target Neighborhood Hits 875 Shared Neighborhood Hits 44
SwissProt Accessions Q60823 Gene names Akt2
Domain
Architecture
Description RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).
GRB14_MOUSE
 
NC score 0.038703 (rank : 135) θ value 5.27518 (rank : 126)
Query Neighborhood Hits 134 Target Neighborhood Hits 149 Shared Neighborhood Hits 23
SwissProt Accessions Q9JLM9, Q3UI77, Q8VDI2, Q9CR03 Gene names Grb14
Domain
Architecture
Description Growth factor receptor-bound protein 14 (GRB14 adapter protein).
AKT1_HUMAN
 
NC score 0.036235 (rank : 136) θ value 0.0431538 (rank : 71)
Query Neighborhood Hits 134 Target Neighborhood Hits 885 Shared Neighborhood Hits 52
SwissProt Accessions P31749, Q9BWB6 Gene names AKT1, PKB, RAC
Domain
Architecture
Description RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).
AKT1_MOUSE
 
NC score 0.035605 (rank : 137) θ value 0.0563607 (rank : 74)
Query Neighborhood Hits 134 Target Neighborhood Hits 878 Shared Neighborhood Hits 51
SwissProt Accessions P31750, Q62274 Gene names Akt1, Akt, Rac
Domain
Architecture
Description RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).
AKT3_HUMAN
 
NC score 0.031613 (rank : 138) θ value 0.0961366 (rank : 76)
Query Neighborhood Hits 134 Target Neighborhood Hits 872 Shared Neighborhood Hits 40
SwissProt Accessions Q9Y243, Q96QV3, Q9UFP5 Gene names AKT3
Domain
Architecture
Description RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).
AKT3_MOUSE
 
NC score 0.031607 (rank : 139) θ value 0.0961366 (rank : 77)
Query Neighborhood Hits 134 Target Neighborhood Hits 872 Shared Neighborhood Hits 40
SwissProt Accessions Q9WUA6 Gene names Akt3
Domain
Architecture
Description RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).
RAPH1_HUMAN
 
NC score 0.026330 (rank : 140) θ value 6.88961 (rank : 131)
Query Neighborhood Hits 134 Target Neighborhood Hits 593 Shared Neighborhood Hits 22
SwissProt Accessions Q70E73, Q96Q37, Q9C0I2 Gene names RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain
Architecture

No domain graphic available

Description Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).
TEC_HUMAN
 
NC score 0.025054 (rank : 141) θ value 5.27518 (rank : 127)
Query Neighborhood Hits 134 Target Neighborhood Hits 1006 Shared Neighborhood Hits 32
SwissProt Accessions P42680 Gene names TEC, PSCTK4
Domain
Architecture
Description Tyrosine-protein kinase Tec (EC 2.7.10.2).
CENG1_MOUSE
 
NC score 0.020669 (rank : 142) θ value 8.99809 (rank : 134)
Query Neighborhood Hits 134 Target Neighborhood Hits 531 Shared Neighborhood Hits 18
SwissProt Accessions Q3UHD9, Q5DU45 Gene names Centg1, Agap2, Kiaa0167
Domain
Architecture

No domain graphic available

Description Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).
CENG1_HUMAN
 
NC score 0.020269 (rank : 143) θ value 8.99809 (rank : 133)
Query Neighborhood Hits 134 Target Neighborhood Hits 544 Shared Neighborhood Hits 18
SwissProt Accessions Q99490, O00578, Q548E0, Q8IWU3 Gene names CENTG1, AGAP2, KIAA0167
Domain
Architecture
Description Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).
BMX_HUMAN
 
NC score 0.014283 (rank : 144) θ value 2.36792 (rank : 112)
Query Neighborhood Hits 134 Target Neighborhood Hits 942 Shared Neighborhood Hits 48
SwissProt Accessions P51813, O60564, Q12871 Gene names BMX
Domain
Architecture
Description Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).
BMX_MOUSE
 
NC score 0.012077 (rank : 145) θ value 3.0926 (rank : 116)
Query Neighborhood Hits 134 Target Neighborhood Hits 912 Shared Neighborhood Hits 45
SwissProt Accessions P97504 Gene names Bmx
Domain
Architecture

No domain graphic available

Description Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).
MYH9_MOUSE
 
NC score 0.011601 (rank : 146) θ value 3.0926 (rank : 121)
Query Neighborhood Hits 134 Target Neighborhood Hits 1829 Shared Neighborhood Hits 36
SwissProt Accessions Q8VDD5 Gene names Myh9
Domain
Architecture

No domain graphic available

Description Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).
VASP_HUMAN
 
NC score 0.011158 (rank : 147) θ value 5.27518 (rank : 128)
Query Neighborhood Hits 134 Target Neighborhood Hits 201 Shared Neighborhood Hits 5
SwissProt Accessions P50552, Q6PIZ1, Q93035 Gene names VASP
Domain
Architecture
Description Vasodilator-stimulated phosphoprotein (VASP).
MYH9_HUMAN
 
NC score 0.011100 (rank : 148) θ value 3.0926 (rank : 120)
Query Neighborhood Hits 134 Target Neighborhood Hits 1762 Shared Neighborhood Hits 32
SwissProt Accessions P35579, O60805 Gene names MYH9
Domain
Architecture
Description Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).
SMC2_MOUSE
 
NC score 0.008408 (rank : 149) θ value 3.0926 (rank : 122)
Query Neighborhood Hits 134 Target Neighborhood Hits 1131 Shared Neighborhood Hits 20
SwissProt Accessions Q8CG48, Q61076, Q9CS17, Q9CSD8 Gene names Smc2l1, Cape, Fin16, Smc2
Domain
Architecture
Description Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).
LAMB1_HUMAN
 
NC score 0.005741 (rank : 150) θ value 1.81305 (rank : 108)
Query Neighborhood Hits 134 Target Neighborhood Hits 1018 Shared Neighborhood Hits 14
SwissProt Accessions P07942 Gene names LAMB1
Domain
Architecture
Description Laminin beta-1 chain precursor (Laminin B1 chain).
LAMB1_MOUSE
 
NC score 0.005374 (rank : 151) θ value 3.0926 (rank : 119)
Query Neighborhood Hits 134 Target Neighborhood Hits 919 Shared Neighborhood Hits 12
SwissProt Accessions P02469 Gene names Lamb1-1, Lamb-1
Domain
Architecture
Description Laminin beta-1 chain precursor (Laminin B1 chain).