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Network neighborhood for query Sequence : GAB1_HUMAN

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GAB1_HUMAN
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GAB1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	279	Target Neighborhood Hits	279	Shared Neighborhood Hits	279
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	0 (rank : 2)	NC score	0.963534 (rank : 2)
Query Neighborhood Hits	279	Target Neighborhood Hits	233	Shared Neighborhood Hits	163
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_HUMAN
θ value	1.09934e-114 (rank : 3)	NC score	0.878932 (rank : 3)
Query Neighborhood Hits	279	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
θ value	2.70778e-113 (rank : 4)	NC score	0.866376 (rank : 4)
Query Neighborhood Hits	279	Target Neighborhood Hits	220	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_MOUSE
θ value	6.21693e-09 (rank : 5)	NC score	0.397588 (rank : 5)
Query Neighborhood Hits	279	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_HUMAN
θ value	1.17247e-07 (rank : 6)	NC score	0.383239 (rank : 6)
Query Neighborhood Hits	279	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

MYO10_HUMAN
θ value	9.92553e-07 (rank : 7)	NC score	0.110615 (rank : 55)
Query Neighborhood Hits	279	Target Neighborhood Hits	920	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PKHA2_MOUSE
θ value	6.43352e-06 (rank : 8)	NC score	0.364459 (rank : 8)
Query Neighborhood Hits	279	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PHLB2_MOUSE
θ value	1.43324e-05 (rank : 9)	NC score	0.179913 (rank : 25)
Query Neighborhood Hits	279	Target Neighborhood Hits	1016	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_HUMAN
θ value	1.87187e-05 (rank : 10)	NC score	0.182200 (rank : 24)
Query Neighborhood Hits	279	Target Neighborhood Hits	964	Shared Neighborhood Hits	52
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

IRS1_HUMAN
θ value	4.1701e-05 (rank : 11)	NC score	0.269459 (rank : 11)
Query Neighborhood Hits	279	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	4.1701e-05 (rank : 12)	NC score	0.264127 (rank : 12)
Query Neighborhood Hits	279	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS2_HUMAN
θ value	5.44631e-05 (rank : 13)	NC score	0.191622 (rank : 22)
Query Neighborhood Hits	279	Target Neighborhood Hits	262	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PKHA2_HUMAN
θ value	5.44631e-05 (rank : 14)	NC score	0.368425 (rank : 7)
Query Neighborhood Hits	279	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PLEK_HUMAN
θ value	5.44631e-05 (rank : 15)	NC score	0.311245 (rank : 9)
Query Neighborhood Hits	279	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	0.000121331 (rank : 16)	NC score	0.305479 (rank : 10)
Query Neighborhood Hits	279	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

IRS2_MOUSE
θ value	0.00020696 (rank : 17)	NC score	0.184686 (rank : 23)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PHLB1_MOUSE
θ value	0.00020696 (rank : 18)	NC score	0.227249 (rank : 15)
Query Neighborhood Hits	279	Target Neighborhood Hits	678	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CNKR1_HUMAN
θ value	0.000602161 (rank : 19)	NC score	0.225505 (rank : 16)
Query Neighborhood Hits	279	Target Neighborhood Hits	154	Shared Neighborhood Hits	43
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

DAPP1_MOUSE
θ value	0.000602161 (rank : 20)	NC score	0.241104 (rank : 13)
Query Neighborhood Hits	279	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PHLB1_HUMAN
θ value	0.000602161 (rank : 21)	NC score	0.206826 (rank : 19)
Query Neighborhood Hits	279	Target Neighborhood Hits	1038	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

DAPP1_HUMAN
θ value	0.000786445 (rank : 22)	NC score	0.239300 (rank : 14)
Query Neighborhood Hits	279	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RAPH1_HUMAN
θ value	0.00228821 (rank : 23)	NC score	0.131673 (rank : 34)
Query Neighborhood Hits	279	Target Neighborhood Hits	593	Shared Neighborhood Hits	87
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CNKR2_HUMAN
θ value	0.00298849 (rank : 24)	NC score	0.219007 (rank : 18)
Query Neighborhood Hits	279	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.00298849 (rank : 25)	NC score	0.219142 (rank : 17)
Query Neighborhood Hits	279	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

BTBDC_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.122920 (rank : 42)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

SRRM2_HUMAN
θ value	0.00509761 (rank : 27)	NC score	0.148427 (rank : 28)
Query Neighborhood Hits	279	Target Neighborhood Hits	1296	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CASL_MOUSE
θ value	0.00869519 (rank : 28)	NC score	0.089655 (rank : 68)
Query Neighborhood Hits	279	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

FIP1_MOUSE
θ value	0.00869519 (rank : 29)	NC score	0.098545 (rank : 59)
Query Neighborhood Hits	279	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

3BP1_HUMAN
θ value	0.0148317 (rank : 30)	NC score	0.063404 (rank : 131)
Query Neighborhood Hits	279	Target Neighborhood Hits	376	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CASL_HUMAN
θ value	0.0148317 (rank : 31)	NC score	0.093287 (rank : 61)
Query Neighborhood Hits	279	Target Neighborhood Hits	259	Shared Neighborhood Hits	28
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PININ_HUMAN
θ value	0.0148317 (rank : 32)	NC score	0.054144 (rank : 170)
Query Neighborhood Hits	279	Target Neighborhood Hits	753	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

IWS1_HUMAN
θ value	0.0193708 (rank : 33)	NC score	0.071830 (rank : 109)
Query Neighborhood Hits	279	Target Neighborhood Hits	1241	Shared Neighborhood Hits	80
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MUC1_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.112409 (rank : 52)
Query Neighborhood Hits	279	Target Neighborhood Hits	975	Shared Neighborhood Hits	126
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BMX_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.028578 (rank : 260)
Query Neighborhood Hits	279	Target Neighborhood Hits	942	Shared Neighborhood Hits	43
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

RPB1_HUMAN
θ value	0.0252991 (rank : 36)	NC score	0.125566 (rank : 40)
Query Neighborhood Hits	279	Target Neighborhood Hits	362	Shared Neighborhood Hits	36
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.0252991 (rank : 37)	NC score	0.125808 (rank : 39)
Query Neighborhood Hits	279	Target Neighborhood Hits	363	Shared Neighborhood Hits	36
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SWP70_MOUSE
θ value	0.0252991 (rank : 38)	NC score	0.123021 (rank : 41)
Query Neighborhood Hits	279	Target Neighborhood Hits	1097	Shared Neighborhood Hits	66
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

BMX_MOUSE
θ value	0.0431538 (rank : 39)	NC score	0.027156 (rank : 262)
Query Neighborhood Hits	279	Target Neighborhood Hits	912	Shared Neighborhood Hits	42
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

GGN_MOUSE
θ value	0.0431538 (rank : 40)	NC score	0.079361 (rank : 88)
Query Neighborhood Hits	279	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MAP4_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.076536 (rank : 94)
Query Neighborhood Hits	279	Target Neighborhood Hits	428	Shared Neighborhood Hits	64
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RHG25_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.133909 (rank : 32)
Query Neighborhood Hits	279	Target Neighborhood Hits	550	Shared Neighborhood Hits	57
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRRM1_HUMAN
θ value	0.0563607 (rank : 43)	NC score	0.126047 (rank : 38)
Query Neighborhood Hits	279	Target Neighborhood Hits	690	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CEND2_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.112324 (rank : 53)
Query Neighborhood Hits	279	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SWP70_HUMAN
θ value	0.0736092 (rank : 45)	NC score	0.120352 (rank : 46)
Query Neighborhood Hits	279	Target Neighborhood Hits	973	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

DOCK9_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.082274 (rank : 80)
Query Neighborhood Hits	279	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

FIP1_HUMAN
θ value	0.0961366 (rank : 47)	NC score	0.089164 (rank : 70)
Query Neighborhood Hits	279	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

PKHA5_HUMAN
θ value	0.0961366 (rank : 48)	NC score	0.160093 (rank : 26)
Query Neighborhood Hits	279	Target Neighborhood Hits	455	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

GP158_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.047995 (rank : 204)
Query Neighborhood Hits	279	Target Neighborhood Hits	221	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

MLL2_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.074278 (rank : 101)
Query Neighborhood Hits	279	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SRRM1_MOUSE
θ value	0.125558 (rank : 51)	NC score	0.135294 (rank : 31)
Query Neighborhood Hits	279	Target Neighborhood Hits	966	Shared Neighborhood Hits	109
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

WASF1_HUMAN
θ value	0.125558 (rank : 52)	NC score	0.083194 (rank : 79)
Query Neighborhood Hits	279	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

DOCK9_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.091566 (rank : 65)
Query Neighborhood Hits	279	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

SN1L2_MOUSE
θ value	0.163984 (rank : 54)	NC score	0.010678 (rank : 315)
Query Neighborhood Hits	279	Target Neighborhood Hits	944	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

TARSH_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.136459 (rank : 30)
Query Neighborhood Hits	279	Target Neighborhood Hits	768	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

WASIP_MOUSE
θ value	0.163984 (rank : 56)	NC score	0.119198 (rank : 48)
Query Neighborhood Hits	279	Target Neighborhood Hits	392	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MRIP_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.133416 (rank : 33)
Query Neighborhood Hits	279	Target Neighborhood Hits	578	Shared Neighborhood Hits	47
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PRG4_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.069677 (rank : 114)
Query Neighborhood Hits	279	Target Neighborhood Hits	764	Shared Neighborhood Hits	62
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RASA1_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.120417 (rank : 45)
Query Neighborhood Hits	279	Target Neighborhood Hits	258	Shared Neighborhood Hits	40
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

TARA_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.126789 (rank : 37)
Query Neighborhood Hits	279	Target Neighborhood Hits	1626	Shared Neighborhood Hits	141
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.130739 (rank : 35)
Query Neighborhood Hits	279	Target Neighborhood Hits	1133	Shared Neighborhood Hits	107
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCF20_MOUSE
θ value	0.21417 (rank : 62)	NC score	0.062446 (rank : 132)
Query Neighborhood Hits	279	Target Neighborhood Hits	396	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

BAI1_HUMAN
θ value	0.279714 (rank : 63)	NC score	0.032617 (rank : 248)
Query Neighborhood Hits	279	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BLNK_MOUSE
θ value	0.279714 (rank : 64)	NC score	0.090118 (rank : 67)
Query Neighborhood Hits	279	Target Neighborhood Hits	296	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BRD4_MOUSE
θ value	0.279714 (rank : 65)	NC score	0.053366 (rank : 174)
Query Neighborhood Hits	279	Target Neighborhood Hits	845	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTG3_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.058255 (rank : 150)
Query Neighborhood Hits	279	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q14201, Q96ET7	Gene names	BTG3, ANA, TOB5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

CEND1_HUMAN
θ value	0.279714 (rank : 67)	NC score	0.116747 (rank : 49)
Query Neighborhood Hits	279	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DIAP1_HUMAN
θ value	0.279714 (rank : 68)	NC score	0.044177 (rank : 212)
Query Neighborhood Hits	279	Target Neighborhood Hits	784	Shared Neighborhood Hits	46
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

KLF10_MOUSE
θ value	0.279714 (rank : 69)	NC score	0.009340 (rank : 319)
Query Neighborhood Hits	279	Target Neighborhood Hits	741	Shared Neighborhood Hits	18
SwissProt Accessions	O89091	Gene names	Klf10, Gdnfif, Tieg, Tieg1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (GDNF-inducible factor) (Transcription factor GIF) (mGIF).

LAP2_HUMAN
θ value	0.279714 (rank : 70)	NC score	0.013725 (rank : 306)
Query Neighborhood Hits	279	Target Neighborhood Hits	499	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MYST3_MOUSE
θ value	0.279714 (rank : 71)	NC score	0.031752 (rank : 249)
Query Neighborhood Hits	279	Target Neighborhood Hits	688	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RASA2_MOUSE
θ value	0.279714 (rank : 72)	NC score	0.111350 (rank : 54)
Query Neighborhood Hits	279	Target Neighborhood Hits	159	Shared Neighborhood Hits	37
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RHG25_MOUSE
θ value	0.279714 (rank : 73)	NC score	0.115169 (rank : 51)
Query Neighborhood Hits	279	Target Neighborhood Hits	492	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

ZYX_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.041823 (rank : 216)
Query Neighborhood Hits	279	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

BAI1_MOUSE
θ value	0.365318 (rank : 75)	NC score	0.030164 (rank : 255)
Query Neighborhood Hits	279	Target Neighborhood Hits	340	Shared Neighborhood Hits	27
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAT2_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.066990 (rank : 122)
Query Neighborhood Hits	279	Target Neighborhood Hits	931	Shared Neighborhood Hits	93
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENB2_HUMAN
θ value	0.365318 (rank : 77)	NC score	0.087692 (rank : 72)
Query Neighborhood Hits	279	Target Neighborhood Hits	425	Shared Neighborhood Hits	48
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

PLEK2_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.198614 (rank : 20)
Query Neighborhood Hits	279	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	0.365318 (rank : 79)	NC score	0.198359 (rank : 21)
Query Neighborhood Hits	279	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

WASL_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.080326 (rank : 86)
Query Neighborhood Hits	279	Target Neighborhood Hits	312	Shared Neighborhood Hits	42
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BTG3_MOUSE
θ value	0.47712 (rank : 81)	NC score	0.052672 (rank : 179)
Query Neighborhood Hits	279	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P50615, Q62328	Gene names	Btg3, Ana, Tob5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

CELR3_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.012551 (rank : 309)
Query Neighborhood Hits	279	Target Neighborhood Hits	680	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CENB1_HUMAN
θ value	0.47712 (rank : 83)	NC score	0.081465 (rank : 82)
Query Neighborhood Hits	279	Target Neighborhood Hits	383	Shared Neighborhood Hits	44
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

IASPP_MOUSE
θ value	0.47712 (rank : 84)	NC score	0.056212 (rank : 155)
Query Neighborhood Hits	279	Target Neighborhood Hits	1024	Shared Neighborhood Hits	102
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KLF2_MOUSE
θ value	0.47712 (rank : 85)	NC score	0.006528 (rank : 330)
Query Neighborhood Hits	279	Target Neighborhood Hits	738	Shared Neighborhood Hits	12
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

WASL_MOUSE
θ value	0.47712 (rank : 86)	NC score	0.084337 (rank : 78)
Query Neighborhood Hits	279	Target Neighborhood Hits	339	Shared Neighborhood Hits	44
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

AB1IP_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.078373 (rank : 89)
Query Neighborhood Hits	279	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

CCNK_MOUSE
θ value	0.62314 (rank : 88)	NC score	0.054667 (rank : 166)
Query Neighborhood Hits	279	Target Neighborhood Hits	350	Shared Neighborhood Hits	44
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CENB5_HUMAN
θ value	0.62314 (rank : 89)	NC score	0.079718 (rank : 87)
Query Neighborhood Hits	279	Target Neighborhood Hits	395	Shared Neighborhood Hits	47
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CF055_MOUSE
θ value	0.62314 (rank : 90)	NC score	0.058053 (rank : 151)
Query Neighborhood Hits	279	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

MYCB2_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.038606 (rank : 228)
Query Neighborhood Hits	279	Target Neighborhood Hits	390	Shared Neighborhood Hits	28
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PCD15_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.016746 (rank : 295)
Query Neighborhood Hits	279	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PKHA6_MOUSE
θ value	0.62314 (rank : 93)	NC score	0.154750 (rank : 27)
Query Neighborhood Hits	279	Target Neighborhood Hits	591	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SPEG_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.025276 (rank : 268)
Query Neighborhood Hits	279	Target Neighborhood Hits	1959	Shared Neighborhood Hits	124
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ACK1_MOUSE
θ value	0.813845 (rank : 95)	NC score	0.021070 (rank : 282)
Query Neighborhood Hits	279	Target Neighborhood Hits	1080	Shared Neighborhood Hits	79
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

AP180_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.044178 (rank : 211)
Query Neighborhood Hits	279	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

FYB_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.053381 (rank : 173)
Query Neighborhood Hits	279	Target Neighborhood Hits	379	Shared Neighborhood Hits	48
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GSCR1_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.075789 (rank : 99)
Query Neighborhood Hits	279	Target Neighborhood Hits	674	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MRIP_MOUSE
θ value	0.813845 (rank : 99)	NC score	0.121377 (rank : 43)
Query Neighborhood Hits	279	Target Neighborhood Hits	569	Shared Neighborhood Hits	48
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MUC7_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.068938 (rank : 118)
Query Neighborhood Hits	279	Target Neighborhood Hits	538	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.119992 (rank : 47)
Query Neighborhood Hits	279	Target Neighborhood Hits	1866	Shared Neighborhood Hits	159
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRG4_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.072612 (rank : 108)
Query Neighborhood Hits	279	Target Neighborhood Hits	624	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PTN13_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.012091 (rank : 310)
Query Neighborhood Hits	279	Target Neighborhood Hits	426	Shared Neighborhood Hits	20
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SOS2_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.031401 (rank : 251)
Query Neighborhood Hits	279	Target Neighborhood Hits	193	Shared Neighborhood Hits	23
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

WASF1_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.070825 (rank : 111)
Query Neighborhood Hits	279	Target Neighborhood Hits	261	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ATN1_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.055852 (rank : 158)
Query Neighborhood Hits	279	Target Neighborhood Hits	676	Shared Neighborhood Hits	61
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

LR37A_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.061299 (rank : 137)
Query Neighborhood Hits	279	Target Neighborhood Hits	720	Shared Neighborhood Hits	81
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

OSBL3_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.050433 (rank : 193)
Query Neighborhood Hits	279	Target Neighborhood Hits	86	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

RNC_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.064706 (rank : 125)
Query Neighborhood Hits	279	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

UBP2L_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.056028 (rank : 157)
Query Neighborhood Hits	279	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ACK1_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.022657 (rank : 275)
Query Neighborhood Hits	279	Target Neighborhood Hits	1140	Shared Neighborhood Hits	88
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CD2AP_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.030117 (rank : 256)
Query Neighborhood Hits	279	Target Neighborhood Hits	315	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CTDP1_MOUSE
θ value	1.38821 (rank : 113)	NC score	0.039408 (rank : 222)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDEF1_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.055417 (rank : 161)
Query Neighborhood Hits	279	Target Neighborhood Hits	592	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DREB_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.048836 (rank : 202)
Query Neighborhood Hits	279	Target Neighborhood Hits	446	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

HUWE1_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.025091 (rank : 269)
Query Neighborhood Hits	279	Target Neighborhood Hits	406	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

KLF10_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.005004 (rank : 332)
Query Neighborhood Hits	279	Target Neighborhood Hits	744	Shared Neighborhood Hits	16
SwissProt Accessions	Q13118	Gene names	KLF10, TIEG, TIEG1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (EGR-alpha).

OSBL3_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.049647 (rank : 201)
Query Neighborhood Hits	279	Target Neighborhood Hits	93	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PCD16_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.008887 (rank : 321)
Query Neighborhood Hits	279	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PDCD7_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.055374 (rank : 163)
Query Neighborhood Hits	279	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

RASA2_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.092885 (rank : 62)
Query Neighborhood Hits	279	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SHAN1_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.050433 (rank : 194)
Query Neighborhood Hits	279	Target Neighborhood Hits	1041	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

WASF4_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.081371 (rank : 84)
Query Neighborhood Hits	279	Target Neighborhood Hits	282	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ZO1_MOUSE
θ value	1.38821 (rank : 124)	NC score	0.029940 (rank : 258)
Query Neighborhood Hits	279	Target Neighborhood Hits	453	Shared Neighborhood Hits	38
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AF9_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.054695 (rank : 164)
Query Neighborhood Hits	279	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CAC1A_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.018200 (rank : 291)
Query Neighborhood Hits	279	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CBP_MOUSE
θ value	1.81305 (rank : 127)	NC score	0.061682 (rank : 134)
Query Neighborhood Hits	279	Target Neighborhood Hits	1051	Shared Neighborhood Hits	116
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CEND1_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.087852 (rank : 71)
Query Neighborhood Hits	279	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CYH1_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.089633 (rank : 69)
Query Neighborhood Hits	279	Target Neighborhood Hits	184	Shared Neighborhood Hits	53
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

EHMT2_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.022199 (rank : 277)
Query Neighborhood Hits	279	Target Neighborhood Hits	750	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FMN2_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.040066 (rank : 219)
Query Neighborhood Hits	279	Target Neighborhood Hits	484	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HUWE1_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.023788 (rank : 273)
Query Neighborhood Hits	279	Target Neighborhood Hits	443	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

LRP6_MOUSE
θ value	1.81305 (rank : 133)	NC score	0.020635 (rank : 283)
Query Neighborhood Hits	279	Target Neighborhood Hits	232	Shared Neighborhood Hits	8
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

NCOR2_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.050784 (rank : 189)
Query Neighborhood Hits	279	Target Neighborhood Hits	870	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PTN23_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.032784 (rank : 246)
Query Neighborhood Hits	279	Target Neighborhood Hits	646	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RBM16_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.059031 (rank : 144)
Query Neighborhood Hits	279	Target Neighborhood Hits	300	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SHAN2_MOUSE
θ value	1.81305 (rank : 137)	NC score	0.038913 (rank : 225)
Query Neighborhood Hits	279	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

TITIN_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.014678 (rank : 301)
Query Neighborhood Hits	279	Target Neighborhood Hits	2923	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WASIP_HUMAN
θ value	1.81305 (rank : 139)	NC score	0.096111 (rank : 60)
Query Neighborhood Hits	279	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ZYX_MOUSE
θ value	1.81305 (rank : 140)	NC score	0.033523 (rank : 242)
Query Neighborhood Hits	279	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ARI1A_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.052928 (rank : 177)
Query Neighborhood Hits	279	Target Neighborhood Hits	787	Shared Neighborhood Hits	82
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CAC1A_MOUSE
θ value	2.36792 (rank : 142)	NC score	0.014626 (rank : 302)
Query Neighborhood Hits	279	Target Neighborhood Hits	267	Shared Neighborhood Hits	25
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

DPOD3_HUMAN
θ value	2.36792 (rank : 143)	NC score	0.041431 (rank : 217)
Query Neighborhood Hits	279	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

DRD2_MOUSE
θ value	2.36792 (rank : 144)	NC score	0.000555 (rank : 338)
Query Neighborhood Hits	279	Target Neighborhood Hits	779	Shared Neighborhood Hits	10
SwissProt Accessions	P61168, P13953	Gene names	Drd2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

EP300_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.045807 (rank : 209)
Query Neighborhood Hits	279	Target Neighborhood Hits	821	Shared Neighborhood Hits	71
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HECD1_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.018058 (rank : 292)
Query Neighborhood Hits	279	Target Neighborhood Hits	371	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

LRP6_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.020146 (rank : 284)
Query Neighborhood Hits	279	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MTMR5_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.087611 (rank : 73)
Query Neighborhood Hits	279	Target Neighborhood Hits	141	Shared Neighborhood Hits	34
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

PGBM_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.007758 (rank : 326)
Query Neighborhood Hits	279	Target Neighborhood Hits	1113	Shared Neighborhood Hits	19
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PKP4_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.022444 (rank : 276)
Query Neighborhood Hits	279	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

POLS_MOUSE
θ value	2.36792 (rank : 151)	NC score	0.025966 (rank : 267)
Query Neighborhood Hits	279	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

ROBO4_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.013150 (rank : 308)
Query Neighborhood Hits	279	Target Neighborhood Hits	364	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

SCAM3_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.022948 (rank : 274)
Query Neighborhood Hits	279	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	O14828, O15128, Q96FR8, Q9BPY0	Gene names	SCAMP3, PROPIN1
Domain Architecture
Description	Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3).

SETBP_MOUSE
θ value	2.36792 (rank : 154)	NC score	0.058526 (rank : 147)
Query Neighborhood Hits	279	Target Neighborhood Hits	352	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

STX17_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.024801 (rank : 271)
Query Neighborhood Hits	279	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P56962	Gene names	STX17
Domain Architecture
Description	Syntaxin-17 (KAT01814).

TAF3_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.046613 (rank : 206)
Query Neighborhood Hits	279	Target Neighborhood Hits	463	Shared Neighborhood Hits	33
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

WASF2_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.066313 (rank : 123)
Query Neighborhood Hits	279	Target Neighborhood Hits	315	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ABI3_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.030254 (rank : 254)
Query Neighborhood Hits	279	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.024607 (rank : 272)
Query Neighborhood Hits	279	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ATX2_MOUSE
θ value	3.0926 (rank : 160)	NC score	0.052576 (rank : 181)
Query Neighborhood Hits	279	Target Neighborhood Hits	445	Shared Neighborhood Hits	73
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BAG3_MOUSE
θ value	3.0926 (rank : 161)	NC score	0.076185 (rank : 96)
Query Neighborhood Hits	279	Target Neighborhood Hits	513	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BCL9_HUMAN
θ value	3.0926 (rank : 162)	NC score	0.087489 (rank : 74)
Query Neighborhood Hits	279	Target Neighborhood Hits	1008	Shared Neighborhood Hits	133
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BSN_MOUSE
θ value	3.0926 (rank : 163)	NC score	0.074081 (rank : 102)
Query Neighborhood Hits	279	Target Neighborhood Hits	2057	Shared Neighborhood Hits	148
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

C43BP_MOUSE
θ value	3.0926 (rank : 164)	NC score	0.108464 (rank : 56)
Query Neighborhood Hits	279	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CBLB_HUMAN
θ value	3.0926 (rank : 165)	NC score	0.019049 (rank : 288)
Query Neighborhood Hits	279	Target Neighborhood Hits	261	Shared Neighborhood Hits	23
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CYH1_MOUSE
θ value	3.0926 (rank : 166)	NC score	0.086343 (rank : 75)
Query Neighborhood Hits	279	Target Neighborhood Hits	176	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

HXB4_HUMAN
θ value	3.0926 (rank : 167)	NC score	0.004822 (rank : 333)
Query Neighborhood Hits	279	Target Neighborhood Hits	376	Shared Neighborhood Hits	11
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

LTBP4_MOUSE
θ value	3.0926 (rank : 168)	NC score	0.011083 (rank : 313)
Query Neighborhood Hits	279	Target Neighborhood Hits	607	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

M3K11_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.009005 (rank : 320)
Query Neighborhood Hits	279	Target Neighborhood Hits	1136	Shared Neighborhood Hits	45
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MINT_MOUSE
θ value	3.0926 (rank : 170)	NC score	0.063430 (rank : 129)
Query Neighborhood Hits	279	Target Neighborhood Hits	1514	Shared Neighborhood Hits	127
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL4_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.052049 (rank : 183)
Query Neighborhood Hits	279	Target Neighborhood Hits	722	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MUC2_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.046830 (rank : 205)
Query Neighborhood Hits	279	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

S23IP_HUMAN
θ value	3.0926 (rank : 173)	NC score	0.036270 (rank : 235)
Query Neighborhood Hits	279	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

SF3A2_MOUSE
θ value	3.0926 (rank : 174)	NC score	0.061976 (rank : 133)
Query Neighborhood Hits	279	Target Neighborhood Hits	247	Shared Neighborhood Hits	33
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

TCF20_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.046150 (rank : 208)
Query Neighborhood Hits	279	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TREF1_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.016747 (rank : 294)
Query Neighborhood Hits	279	Target Neighborhood Hits	682	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

WASF2_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.069400 (rank : 117)
Query Neighborhood Hits	279	Target Neighborhood Hits	280	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ARHG7_MOUSE
θ value	4.03905 (rank : 178)	NC score	0.024986 (rank : 270)
Query Neighborhood Hits	279	Target Neighborhood Hits	396	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CABYR_MOUSE
θ value	4.03905 (rank : 179)	NC score	0.036577 (rank : 232)
Query Neighborhood Hits	279	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CF055_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.038718 (rank : 227)
Query Neighborhood Hits	279	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

CJ026_MOUSE
θ value	4.03905 (rank : 181)	NC score	0.030020 (rank : 257)
Query Neighborhood Hits	279	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

CN092_MOUSE
θ value	4.03905 (rank : 182)	NC score	0.026486 (rank : 265)
Query Neighborhood Hits	279	Target Neighborhood Hits	206	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

DAB2_MOUSE
θ value	4.03905 (rank : 183)	NC score	0.030737 (rank : 252)
Query Neighborhood Hits	279	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

DGKH_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.057903 (rank : 152)
Query Neighborhood Hits	279	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DOT1L_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.048804 (rank : 203)
Query Neighborhood Hits	279	Target Neighborhood Hits	660	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EGR2_MOUSE
θ value	4.03905 (rank : 186)	NC score	0.006281 (rank : 331)
Query Neighborhood Hits	279	Target Neighborhood Hits	745	Shared Neighborhood Hits	19
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

FBLI1_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.020084 (rank : 285)
Query Neighborhood Hits	279	Target Neighborhood Hits	200	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

GNAS3_HUMAN
θ value	4.03905 (rank : 188)	NC score	0.053955 (rank : 171)
Query Neighborhood Hits	279	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

HXB4_MOUSE
θ value	4.03905 (rank : 189)	NC score	0.003799 (rank : 334)
Query Neighborhood Hits	279	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

MAGE1_HUMAN
θ value	4.03905 (rank : 190)	NC score	0.070650 (rank : 112)
Query Neighborhood Hits	279	Target Neighborhood Hits	1389	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MNT_HUMAN
θ value	4.03905 (rank : 191)	NC score	0.044685 (rank : 210)
Query Neighborhood Hits	279	Target Neighborhood Hits	496	Shared Neighborhood Hits	69
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NCOA6_HUMAN
θ value	4.03905 (rank : 192)	NC score	0.091652 (rank : 63)
Query Neighborhood Hits	279	Target Neighborhood Hits	1202	Shared Neighborhood Hits	146
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NGAP_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.026740 (rank : 264)
Query Neighborhood Hits	279	Target Neighborhood Hits	517	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

PAPOG_MOUSE
θ value	4.03905 (rank : 194)	NC score	0.013640 (rank : 307)
Query Neighborhood Hits	279	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

PCLO_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.081907 (rank : 81)
Query Neighborhood Hits	279	Target Neighborhood Hits	2046	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHF3_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.033525 (rank : 241)
Query Neighborhood Hits	279	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PTCD1_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.021568 (rank : 280)
Query Neighborhood Hits	279	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

SYNJ1_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.050605 (rank : 192)
Query Neighborhood Hits	279	Target Neighborhood Hits	516	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYTL2_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.015522 (rank : 297)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TM55A_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.021261 (rank : 281)
Query Neighborhood Hits	279	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N4L2, Q68CU2	Gene names	TMEM55A
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

ZCHC8_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.043231 (rank : 214)
Query Neighborhood Hits	279	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

ALEX_HUMAN
θ value	5.27518 (rank : 202)	NC score	0.055796 (rank : 160)
Query Neighborhood Hits	279	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

HIC1_MOUSE
θ value	5.27518 (rank : 203)	NC score	-0.000759 (rank : 340)
Query Neighborhood Hits	279	Target Neighborhood Hits	863	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

HRX_HUMAN
θ value	5.27518 (rank : 204)	NC score	0.046334 (rank : 207)
Query Neighborhood Hits	279	Target Neighborhood Hits	825	Shared Neighborhood Hits	69
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LCP2_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.104076 (rank : 57)
Query Neighborhood Hits	279	Target Neighborhood Hits	531	Shared Neighborhood Hits	106
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PCLO_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.068304 (rank : 120)
Query Neighborhood Hits	279	Target Neighborhood Hits	2275	Shared Neighborhood Hits	164
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCTK2_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.001959 (rank : 336)
Query Neighborhood Hits	279	Target Neighborhood Hits	837	Shared Neighborhood Hits	14
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

RBL2_MOUSE
θ value	5.27518 (rank : 208)	NC score	0.011082 (rank : 314)
Query Neighborhood Hits	279	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q64700	Gene names	Rbl2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

RGS3_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.059707 (rank : 142)
Query Neighborhood Hits	279	Target Neighborhood Hits	1375	Shared Neighborhood Hits	158
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SF01_HUMAN
θ value	5.27518 (rank : 210)	NC score	0.038906 (rank : 226)
Query Neighborhood Hits	279	Target Neighborhood Hits	287	Shared Neighborhood Hits	43
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	5.27518 (rank : 211)	NC score	0.034028 (rank : 240)
Query Neighborhood Hits	279	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.054321 (rank : 169)
Query Neighborhood Hits	279	Target Neighborhood Hits	263	Shared Neighborhood Hits	32
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.036753 (rank : 231)
Query Neighborhood Hits	279	Target Neighborhood Hits	958	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SMAD2_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.010236 (rank : 318)
Query Neighborhood Hits	279	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

SMAD2_MOUSE
θ value	5.27518 (rank : 215)	NC score	0.010237 (rank : 317)
Query Neighborhood Hits	279	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SYNJ2_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.018468 (rank : 290)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

TAF4_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.052499 (rank : 182)
Query Neighborhood Hits	279	Target Neighborhood Hits	687	Shared Neighborhood Hits	58
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TBCD5_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.014408 (rank : 304)
Query Neighborhood Hits	279	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

TRPS1_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.007808 (rank : 325)
Query Neighborhood Hits	279	Target Neighborhood Hits	609	Shared Neighborhood Hits	12
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

TTP_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.016967 (rank : 293)
Query Neighborhood Hits	279	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

WIRE_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.075444 (rank : 100)
Query Neighborhood Hits	279	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

YLPM1_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.039932 (rank : 220)
Query Neighborhood Hits	279	Target Neighborhood Hits	505	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ABHD5_HUMAN
θ value	6.88961 (rank : 223)	NC score	0.010414 (rank : 316)
Query Neighborhood Hits	279	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTS1, Q9Y369	Gene names	ABHD5, NCIE2
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5.

AIPL1_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.011695 (rank : 312)
Query Neighborhood Hits	279	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

APC_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.034895 (rank : 237)
Query Neighborhood Hits	279	Target Neighborhood Hits	603	Shared Neighborhood Hits	51
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BAT3_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.043561 (rank : 213)
Query Neighborhood Hits	279	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CTBP1_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.008736 (rank : 322)
Query Neighborhood Hits	279	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

FBLI1_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.027849 (rank : 261)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

FHOD1_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.039318 (rank : 223)
Query Neighborhood Hits	279	Target Neighborhood Hits	217	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GAK6_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.033075 (rank : 243)
Query Neighborhood Hits	279	Target Neighborhood Hits	392	Shared Neighborhood Hits	91
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HIC1_HUMAN
θ value	6.88961 (rank : 231)	NC score	-0.001495 (rank : 341)
Query Neighborhood Hits	279	Target Neighborhood Hits	838	Shared Neighborhood Hits	14
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HNRL1_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.036525 (rank : 234)
Query Neighborhood Hits	279	Target Neighborhood Hits	200	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

NECD_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.015985 (rank : 296)
Query Neighborhood Hits	279	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

OSBL6_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.036533 (rank : 233)
Query Neighborhood Hits	279	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	6.88961 (rank : 235)	NC score	0.036870 (rank : 230)
Query Neighborhood Hits	279	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PRR12_HUMAN
θ value	6.88961 (rank : 236)	NC score	0.064164 (rank : 126)
Query Neighborhood Hits	279	Target Neighborhood Hits	460	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RT18A_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.015345 (rank : 299)
Query Neighborhood Hits	279	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVS2	Gene names	MRPS18A
Domain Architecture
Description	28S ribosomal protein S18a, mitochondrial precursor (MRP-S18-a) (Mrps18a) (MRP-S18-3).

ST5_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.015509 (rank : 298)
Query Neighborhood Hits	279	Target Neighborhood Hits	151	Shared Neighborhood Hits	23
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

SYNJ1_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.053352 (rank : 175)
Query Neighborhood Hits	279	Target Neighborhood Hits	498	Shared Neighborhood Hits	77
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TM55A_MOUSE
θ value	6.88961 (rank : 240)	NC score	0.018726 (rank : 289)
Query Neighborhood Hits	279	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZX7	Gene names	Tmem55a
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

WASP_HUMAN
θ value	6.88961 (rank : 241)	NC score	0.050015 (rank : 199)
Query Neighborhood Hits	279	Target Neighborhood Hits	195	Shared Neighborhood Hits	28
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WNK4_HUMAN
θ value	6.88961 (rank : 242)	NC score	0.014552 (rank : 303)
Query Neighborhood Hits	279	Target Neighborhood Hits	1043	Shared Neighborhood Hits	43
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZEP1_HUMAN
θ value	6.88961 (rank : 243)	NC score	0.008258 (rank : 323)
Query Neighborhood Hits	279	Target Neighborhood Hits	1036	Shared Neighborhood Hits	59
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZIM10_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.050690 (rank : 190)
Query Neighborhood Hits	279	Target Neighborhood Hits	577	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

AB1IP_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.072767 (rank : 107)
Query Neighborhood Hits	279	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

BOC_MOUSE
θ value	8.99809 (rank : 246)	NC score	0.007885 (rank : 324)
Query Neighborhood Hits	279	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

BRD4_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.042383 (rank : 215)
Query Neighborhood Hits	279	Target Neighborhood Hits	851	Shared Neighborhood Hits	72
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

C43BP_HUMAN
θ value	8.99809 (rank : 248)	NC score	0.085545 (rank : 76)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CBL_HUMAN
θ value	8.99809 (rank : 249)	NC score	0.021903 (rank : 279)
Query Neighborhood Hits	279	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CJ047_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.019783 (rank : 286)
Query Neighborhood Hits	279	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CJ078_MOUSE
θ value	8.99809 (rank : 251)	NC score	0.049840 (rank : 200)
Query Neighborhood Hits	279	Target Neighborhood Hits	559	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CMTA2_MOUSE
θ value	8.99809 (rank : 252)	NC score	0.011907 (rank : 311)
Query Neighborhood Hits	279	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CRTC1_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.040330 (rank : 218)
Query Neighborhood Hits	279	Target Neighborhood Hits	319	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DAXX_MOUSE
θ value	8.99809 (rank : 254)	NC score	0.015018 (rank : 300)
Query Neighborhood Hits	279	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DIAP2_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.019124 (rank : 287)
Query Neighborhood Hits	279	Target Neighborhood Hits	342	Shared Neighborhood Hits	23
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DREB_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.031594 (rank : 250)
Query Neighborhood Hits	279	Target Neighborhood Hits	450	Shared Neighborhood Hits	26
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

ENAH_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.035705 (rank : 236)
Query Neighborhood Hits	279	Target Neighborhood Hits	784	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EPS8_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.007274 (rank : 328)
Query Neighborhood Hits	279	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ERRFI_MOUSE
θ value	8.99809 (rank : 259)	NC score	0.039551 (rank : 221)
Query Neighborhood Hits	279	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

EVI2B_MOUSE
θ value	8.99809 (rank : 260)	NC score	0.026327 (rank : 266)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

GAK11_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.032778 (rank : 247)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	94
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.030568 (rank : 253)
Query Neighborhood Hits	279	Target Neighborhood Hits	374	Shared Neighborhood Hits	90
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	8.99809 (rank : 263)	NC score	0.032864 (rank : 245)
Query Neighborhood Hits	279	Target Neighborhood Hits	406	Shared Neighborhood Hits	95
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.032949 (rank : 244)
Query Neighborhood Hits	279	Target Neighborhood Hits	415	Shared Neighborhood Hits	95
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HNF3A_MOUSE
θ value	8.99809 (rank : 265)	NC score	0.002240 (rank : 335)
Query Neighborhood Hits	279	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	P35582, Q61108	Gene names	Foxa1, Hnf3a, Tcf-3a, Tcf3a
Domain Architecture
Description	Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1).

KSR2_HUMAN
θ value	8.99809 (rank : 266)	NC score	0.007389 (rank : 327)
Query Neighborhood Hits	279	Target Neighborhood Hits	920	Shared Neighborhood Hits	33
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

PCTK2_MOUSE
θ value	8.99809 (rank : 267)	NC score	0.001594 (rank : 337)
Query Neighborhood Hits	279	Target Neighborhood Hits	836	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

PDC6I_MOUSE
θ value	8.99809 (rank : 268)	NC score	0.028862 (rank : 259)
Query Neighborhood Hits	279	Target Neighborhood Hits	275	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PO121_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.034851 (rank : 238)
Query Neighborhood Hits	279	Target Neighborhood Hits	344	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PTN23_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.026804 (rank : 263)
Query Neighborhood Hits	279	Target Neighborhood Hits	726	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RBBP6_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.038122 (rank : 229)
Query Neighborhood Hits	279	Target Neighborhood Hits	1135	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	8.99809 (rank : 272)	NC score	0.034648 (rank : 239)
Query Neighborhood Hits	279	Target Neighborhood Hits	1014	Shared Neighborhood Hits	57
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REXO1_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.039036 (rank : 224)
Query Neighborhood Hits	279	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

STP2_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.021903 (rank : 278)
Query Neighborhood Hits	279	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q05952, Q9NZB0	Gene names	TNP2
Domain Architecture
Description	Nuclear transition protein 2 (TP-2) (TP2).

TBCD2_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.084824 (rank : 77)
Query Neighborhood Hits	279	Target Neighborhood Hits	419	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

WIRE_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.061619 (rank : 135)
Query Neighborhood Hits	279	Target Neighborhood Hits	310	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WNK2_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.013943 (rank : 305)
Query Neighborhood Hits	279	Target Neighborhood Hits	1407	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

XK_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.007004 (rank : 329)
Query Neighborhood Hits	279	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P51811, Q4TTN6, Q8IUK6, Q9UC77	Gene names	XK, XKR1, XRG1
Domain Architecture	No domain graphic available
Description	Membrane transport protein XK (Kx antigen) (Kell complex 37 kDa component) (XK-related protein 1).

ZBT45_HUMAN
θ value	8.99809 (rank : 279)	NC score	-0.000041 (rank : 339)
Query Neighborhood Hits	279	Target Neighborhood Hits	901	Shared Neighborhood Hits	30
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

3BP2_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.076829 (rank : 93)
Query Neighborhood Hits	279	Target Neighborhood Hits	296	Shared Neighborhood Hits	70
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.059547 (rank : 143)
Query Neighborhood Hits	279	Target Neighborhood Hits	142	Shared Neighborhood Hits	29
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BAT2_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.050114 (rank : 198)
Query Neighborhood Hits	279	Target Neighborhood Hits	947	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCAR1_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.069612 (rank : 115)
Query Neighborhood Hits	279	Target Neighborhood Hits	554	Shared Neighborhood Hits	97
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.057502 (rank : 153)
Query Neighborhood Hits	279	Target Neighborhood Hits	438	Shared Neighborhood Hits	79
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL9_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.063587 (rank : 128)
Query Neighborhood Hits	279	Target Neighborhood Hits	770	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BLNK_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.060493 (rank : 139)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BSN_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.063409 (rank : 130)
Query Neighborhood Hits	279	Target Neighborhood Hits	1537	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CBP_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.050265 (rank : 196)
Query Neighborhood Hits	279	Target Neighborhood Hits	941	Shared Neighborhood Hits	100
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD2_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.060361 (rank : 141)
Query Neighborhood Hits	279	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CEL_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.060473 (rank : 140)
Query Neighborhood Hits	279	Target Neighborhood Hits	896	Shared Neighborhood Hits	130
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CENA2_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.051273 (rank : 188)
Query Neighborhood Hits	279	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.050131 (rank : 197)
Query Neighborhood Hits	279	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND3_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.056835 (rank : 154)
Query Neighborhood Hits	279	Target Neighborhood Hits	275	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.054614 (rank : 167)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CK024_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.050637 (rank : 191)
Query Neighborhood Hits	279	Target Neighborhood Hits	408	Shared Neighborhood Hits	64
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CO039_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.056136 (rank : 156)
Query Neighborhood Hits	279	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CS007_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.054679 (rank : 165)
Query Neighborhood Hits	279	Target Neighborhood Hits	464	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CYH2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.076990 (rank : 91)
Query Neighborhood Hits	279	Target Neighborhood Hits	175	Shared Neighborhood Hits	49
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.076966 (rank : 92)
Query Neighborhood Hits	279	Target Neighborhood Hits	171	Shared Neighborhood Hits	49
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.076104 (rank : 97)
Query Neighborhood Hits	279	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.081461 (rank : 83)
Query Neighborhood Hits	279	Target Neighborhood Hits	148	Shared Neighborhood Hits	48
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.076002 (rank : 98)
Query Neighborhood Hits	279	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.076460 (rank : 95)
Query Neighborhood Hits	279	Target Neighborhood Hits	134	Shared Neighborhood Hits	45
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DOC10_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.101432 (rank : 58)
Query Neighborhood Hits	279	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

ENAH_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.053488 (rank : 172)
Query Neighborhood Hits	279	Target Neighborhood Hits	919	Shared Neighborhood Hits	67
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FA47A_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.077533 (rank : 90)
Query Neighborhood Hits	279	Target Neighborhood Hits	451	Shared Neighborhood Hits	99
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.073603 (rank : 104)
Query Neighborhood Hits	279	Target Neighborhood Hits	431	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

IWS1_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.051901 (rank : 186)
Query Neighborhood Hits	279	Target Neighborhood Hits	1258	Shared Neighborhood Hits	96
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1802_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.063805 (rank : 127)
Query Neighborhood Hits	279	Target Neighborhood Hits	1596	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LPP_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.058425 (rank : 149)
Query Neighborhood Hits	279	Target Neighborhood Hits	775	Shared Neighborhood Hits	106
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAP4_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.053203 (rank : 176)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	45
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MDC1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.091591 (rank : 64)
Query Neighborhood Hits	279	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.091379 (rank : 66)
Query Neighborhood Hits	279	Target Neighborhood Hits	998	Shared Neighborhood Hits	118
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MISS_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.061587 (rank : 136)
Query Neighborhood Hits	279	Target Neighborhood Hits	444	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL3_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.073721 (rank : 103)
Query Neighborhood Hits	279	Target Neighborhood Hits	1644	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.069491 (rank : 116)
Query Neighborhood Hits	279	Target Neighborhood Hits	1399	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MTMRD_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.070263 (rank : 113)
Query Neighborhood Hits	279	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

NCOA6_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.070972 (rank : 110)
Query Neighborhood Hits	279	Target Neighborhood Hits	1076	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFH_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.051635 (rank : 187)
Query Neighborhood Hits	279	Target Neighborhood Hits	2247	Shared Neighborhood Hits	143
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.052736 (rank : 178)
Query Neighborhood Hits	279	Target Neighborhood Hits	452	Shared Neighborhood Hits	37
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

OGFR_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.068929 (rank : 119)
Query Neighborhood Hits	279	Target Neighborhood Hits	1582	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OSBL9_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.052033 (rank : 184)
Query Neighborhood Hits	279	Target Neighborhood Hits	138	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBP1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.058470 (rank : 148)
Query Neighborhood Hits	279	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.055388 (rank : 162)
Query Neighborhood Hits	279	Target Neighborhood Hits	150	Shared Neighborhood Hits	42
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PI5PA_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.054355 (rank : 168)
Query Neighborhood Hits	279	Target Neighborhood Hits	749	Shared Neighborhood Hits	103
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA4_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.115616 (rank : 50)
Query Neighborhood Hits	279	Target Neighborhood Hits	283	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.120599 (rank : 44)
Query Neighborhood Hits	279	Target Neighborhood Hits	202	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.143113 (rank : 29)
Query Neighborhood Hits	279	Target Neighborhood Hits	556	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHB2_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.050368 (rank : 195)
Query Neighborhood Hits	279	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PRRT3_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.080528 (rank : 85)
Query Neighborhood Hits	279	Target Neighborhood Hits	998	Shared Neighborhood Hits	133
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RASA3_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.067332 (rank : 121)
Query Neighborhood Hits	279	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.064759 (rank : 124)
Query Neighborhood Hits	279	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RGS3_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.073119 (rank : 106)
Query Neighborhood Hits	279	Target Neighborhood Hits	1621	Shared Neighborhood Hits	161
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RTP3_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.058957 (rank : 145)
Query Neighborhood Hits	279	Target Neighborhood Hits	374	Shared Neighborhood Hits	74
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SELPL_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.055821 (rank : 159)
Query Neighborhood Hits	279	Target Neighborhood Hits	588	Shared Neighborhood Hits	75
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SON_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.073361 (rank : 105)
Query Neighborhood Hits	279	Target Neighborhood Hits	1568	Shared Neighborhood Hits	155
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPR1B_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.052656 (rank : 180)
Query Neighborhood Hits	279	Target Neighborhood Hits	395	Shared Neighborhood Hits	83
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SRRM2_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.126904 (rank : 36)
Query Neighborhood Hits	279	Target Neighborhood Hits	1470	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCGAP_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.060792 (rank : 138)
Query Neighborhood Hits	279	Target Neighborhood Hits	872	Shared Neighborhood Hits	120
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TGON2_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.051993 (rank : 185)
Query Neighborhood Hits	279	Target Neighborhood Hits	1037	Shared Neighborhood Hits	83
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.058789 (rank : 146)
Query Neighborhood Hits	279	Target Neighborhood Hits	793	Shared Neighborhood Hits	88
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

Hits sorted by NC score

GAB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	279	Target Neighborhood Hits	279	Shared Neighborhood Hits	279
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
NC score	0.963534 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	279	Target Neighborhood Hits	233	Shared Neighborhood Hits	163
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_HUMAN
NC score	0.878932 (rank : 3)	θ value	1.09934e-114 (rank : 3)
Query Neighborhood Hits	279	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
NC score	0.866376 (rank : 4)	θ value	2.70778e-113 (rank : 4)
Query Neighborhood Hits	279	Target Neighborhood Hits	220	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_MOUSE
NC score	0.397588 (rank : 5)	θ value	6.21693e-09 (rank : 5)
Query Neighborhood Hits	279	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_HUMAN
NC score	0.383239 (rank : 6)	θ value	1.17247e-07 (rank : 6)
Query Neighborhood Hits	279	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
NC score	0.368425 (rank : 7)	θ value	5.44631e-05 (rank : 14)
Query Neighborhood Hits	279	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
NC score	0.364459 (rank : 8)	θ value	6.43352e-06 (rank : 8)
Query Neighborhood Hits	279	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PLEK_HUMAN
NC score	0.311245 (rank : 9)	θ value	5.44631e-05 (rank : 15)
Query Neighborhood Hits	279	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
NC score	0.305479 (rank : 10)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	279	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

IRS1_HUMAN
NC score	0.269459 (rank : 11)	θ value	4.1701e-05 (rank : 11)
Query Neighborhood Hits	279	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
NC score	0.264127 (rank : 12)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	279	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

DAPP1_MOUSE
NC score	0.241104 (rank : 13)	θ value	0.000602161 (rank : 20)
Query Neighborhood Hits	279	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.239300 (rank : 14)	θ value	0.000786445 (rank : 22)
Query Neighborhood Hits	279	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PHLB1_MOUSE
NC score	0.227249 (rank : 15)	θ value	0.00020696 (rank : 18)
Query Neighborhood Hits	279	Target Neighborhood Hits	678	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CNKR1_HUMAN
NC score	0.225505 (rank : 16)	θ value	0.000602161 (rank : 19)
Query Neighborhood Hits	279	Target Neighborhood Hits	154	Shared Neighborhood Hits	43
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_MOUSE
NC score	0.219142 (rank : 17)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	279	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.219007 (rank : 18)	θ value	0.00298849 (rank : 24)
Query Neighborhood Hits	279	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PHLB1_HUMAN
NC score	0.206826 (rank : 19)	θ value	0.000602161 (rank : 21)
Query Neighborhood Hits	279	Target Neighborhood Hits	1038	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PLEK2_HUMAN
NC score	0.198614 (rank : 20)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	279	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
NC score	0.198359 (rank : 21)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	279	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

IRS2_HUMAN
NC score	0.191622 (rank : 22)	θ value	5.44631e-05 (rank : 13)
Query Neighborhood Hits	279	Target Neighborhood Hits	262	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

IRS2_MOUSE
NC score	0.184686 (rank : 23)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PHLB2_HUMAN
NC score	0.182200 (rank : 24)	θ value	1.87187e-05 (rank : 10)
Query Neighborhood Hits	279	Target Neighborhood Hits	964	Shared Neighborhood Hits	52
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
NC score	0.179913 (rank : 25)	θ value	1.43324e-05 (rank : 9)
Query Neighborhood Hits	279	Target Neighborhood Hits	1016	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA5_HUMAN
NC score	0.160093 (rank : 26)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	279	Target Neighborhood Hits	455	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_MOUSE
NC score	0.154750 (rank : 27)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	279	Target Neighborhood Hits	591	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SRRM2_HUMAN
NC score	0.148427 (rank : 28)	θ value	0.00509761 (rank : 27)
Query Neighborhood Hits	279	Target Neighborhood Hits	1296	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PKHA6_HUMAN
NC score	0.143113 (rank : 29)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	279	Target Neighborhood Hits	556	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TARSH_HUMAN
NC score	0.136459 (rank : 30)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	279	Target Neighborhood Hits	768	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SRRM1_MOUSE
NC score	0.135294 (rank : 31)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	279	Target Neighborhood Hits	966	Shared Neighborhood Hits	109
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

RHG25_HUMAN
NC score	0.133909 (rank : 32)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	279	Target Neighborhood Hits	550	Shared Neighborhood Hits	57
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MRIP_HUMAN
NC score	0.133416 (rank : 33)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	279	Target Neighborhood Hits	578	Shared Neighborhood Hits	47
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

RAPH1_HUMAN
NC score	0.131673 (rank : 34)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	279	Target Neighborhood Hits	593	Shared Neighborhood Hits	87
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TARA_MOUSE
NC score	0.130739 (rank : 35)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	279	Target Neighborhood Hits	1133	Shared Neighborhood Hits	107
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM2_MOUSE
NC score	0.126904 (rank : 36)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	279	Target Neighborhood Hits	1470	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARA_HUMAN
NC score	0.126789 (rank : 37)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	279	Target Neighborhood Hits	1626	Shared Neighborhood Hits	141
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM1_HUMAN
NC score	0.126047 (rank : 38)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	279	Target Neighborhood Hits	690	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

RPB1_MOUSE
NC score	0.125808 (rank : 39)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	279	Target Neighborhood Hits	363	Shared Neighborhood Hits	36
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.125566 (rank : 40)	θ value	0.0252991 (rank : 36)
Query Neighborhood Hits	279	Target Neighborhood Hits	362	Shared Neighborhood Hits	36
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SWP70_MOUSE
NC score	0.123021 (rank : 41)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	279	Target Neighborhood Hits	1097	Shared Neighborhood Hits	66
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

BTBDC_HUMAN
NC score	0.122920 (rank : 42)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MRIP_MOUSE
NC score	0.121377 (rank : 43)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	279	Target Neighborhood Hits	569	Shared Neighborhood Hits	48
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PKHA4_MOUSE
NC score	0.120599 (rank : 44)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	279	Target Neighborhood Hits	202	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RASA1_HUMAN
NC score	0.120417 (rank : 45)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	279	Target Neighborhood Hits	258	Shared Neighborhood Hits	40
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SWP70_HUMAN
NC score	0.120352 (rank : 46)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	279	Target Neighborhood Hits	973	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NACAM_MOUSE
NC score	0.119992 (rank : 47)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	279	Target Neighborhood Hits	1866	Shared Neighborhood Hits	159
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WASIP_MOUSE
NC score	0.119198 (rank : 48)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	279	Target Neighborhood Hits	392	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CEND1_HUMAN
NC score	0.116747 (rank : 49)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	279	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

PKHA4_HUMAN
NC score	0.115616 (rank : 50)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	279	Target Neighborhood Hits	283	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RHG25_MOUSE
NC score	0.115169 (rank : 51)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	279	Target Neighborhood Hits	492	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MUC1_HUMAN
NC score	0.112409 (rank : 52)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	279	Target Neighborhood Hits	975	Shared Neighborhood Hits	126
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CEND2_HUMAN
NC score	0.112324 (rank : 53)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	279	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RASA2_MOUSE
NC score	0.111350 (rank : 54)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	279	Target Neighborhood Hits	159	Shared Neighborhood Hits	37
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

MYO10_HUMAN
NC score	0.110615 (rank : 55)	θ value	9.92553e-07 (rank : 7)
Query Neighborhood Hits	279	Target Neighborhood Hits	920	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

C43BP_MOUSE
NC score	0.108464 (rank : 56)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	279	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

LCP2_HUMAN
NC score	0.104076 (rank : 57)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	279	Target Neighborhood Hits	531	Shared Neighborhood Hits	106
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

DOC10_HUMAN
NC score	0.101432 (rank : 58)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	279	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

FIP1_MOUSE
NC score	0.098545 (rank : 59)	θ value	0.00869519 (rank : 29)
Query Neighborhood Hits	279	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

WASIP_HUMAN
NC score	0.096111 (rank : 60)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	279	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CASL_HUMAN
NC score	0.093287 (rank : 61)	θ value	0.0148317 (rank : 31)
Query Neighborhood Hits	279	Target Neighborhood Hits	259	Shared Neighborhood Hits	28
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

RASA2_HUMAN
NC score	0.092885 (rank : 62)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	279	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

NCOA6_HUMAN
NC score	0.091652 (rank : 63)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	279	Target Neighborhood Hits	1202	Shared Neighborhood Hits	146
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MDC1_HUMAN
NC score	0.091591 (rank : 64)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	279	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DOCK9_MOUSE
NC score	0.091566 (rank : 65)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	279	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

MDC1_MOUSE
NC score	0.091379 (rank : 66)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	279	Target Neighborhood Hits	998	Shared Neighborhood Hits	118
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BLNK_MOUSE
NC score	0.090118 (rank : 67)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	279	Target Neighborhood Hits	296	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CASL_MOUSE
NC score	0.089655 (rank : 68)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	279	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CYH1_HUMAN
NC score	0.089633 (rank : 69)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	279	Target Neighborhood Hits	184	Shared Neighborhood Hits	53
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

FIP1_HUMAN
NC score	0.089164 (rank : 70)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	279	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

CEND1_MOUSE
NC score	0.087852 (rank : 71)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	279	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CENB2_HUMAN
NC score	0.087692 (rank : 72)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	279	Target Neighborhood Hits	425	Shared Neighborhood Hits	48
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

MTMR5_HUMAN
NC score	0.087611 (rank : 73)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	279	Target Neighborhood Hits	141	Shared Neighborhood Hits	34
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

BCL9_HUMAN
NC score	0.087489 (rank : 74)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	279	Target Neighborhood Hits	1008	Shared Neighborhood Hits	133
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CYH1_MOUSE
NC score	0.086343 (rank : 75)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	279	Target Neighborhood Hits	176	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

C43BP_HUMAN
NC score	0.085545 (rank : 76)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

TBCD2_HUMAN
NC score	0.084824 (rank : 77)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	279	Target Neighborhood Hits	419	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

WASL_MOUSE
NC score	0.084337 (rank : 78)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	279	Target Neighborhood Hits	339	Shared Neighborhood Hits	44
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASF1_HUMAN
NC score	0.083194 (rank : 79)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	279	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

DOCK9_HUMAN
NC score	0.082274 (rank : 80)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	279	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

PCLO_HUMAN
NC score	0.081907 (rank : 81)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	279	Target Neighborhood Hits	2046	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CENB1_HUMAN
NC score	0.081465 (rank : 82)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	279	Target Neighborhood Hits	383	Shared Neighborhood Hits	44
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CYH3_MOUSE
NC score	0.081461 (rank : 83)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	279	Target Neighborhood Hits	148	Shared Neighborhood Hits	48
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

WASF4_HUMAN
NC score	0.081371 (rank : 84)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	279	Target Neighborhood Hits	282	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

PRRT3_HUMAN
NC score	0.080528 (rank : 85)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	279	Target Neighborhood Hits	998	Shared Neighborhood Hits	133
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WASL_HUMAN
NC score	0.080326 (rank : 86)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	279	Target Neighborhood Hits	312	Shared Neighborhood Hits	42
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CENB5_HUMAN
NC score	0.079718 (rank : 87)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	279	Target Neighborhood Hits	395	Shared Neighborhood Hits	47
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

GGN_MOUSE
NC score	0.079361 (rank : 88)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	279	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

AB1IP_MOUSE
NC score	0.078373 (rank : 89)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	279	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

FA47A_HUMAN
NC score	0.077533 (rank : 90)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	279	Target Neighborhood Hits	451	Shared Neighborhood Hits	99
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CYH2_HUMAN
NC score	0.076990 (rank : 91)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	279	Target Neighborhood Hits	175	Shared Neighborhood Hits	49
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.076966 (rank : 92)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	279	Target Neighborhood Hits	171	Shared Neighborhood Hits	49
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

3BP2_HUMAN
NC score	0.076829 (rank : 93)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	279	Target Neighborhood Hits	296	Shared Neighborhood Hits	70
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MAP4_HUMAN
NC score	0.076536 (rank : 94)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	279	Target Neighborhood Hits	428	Shared Neighborhood Hits	64
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CYH4_MOUSE
NC score	0.076460 (rank : 95)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	279	Target Neighborhood Hits	134	Shared Neighborhood Hits	45
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

BAG3_MOUSE
NC score	0.076185 (rank : 96)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	279	Target Neighborhood Hits	513	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CYH3_HUMAN
NC score	0.076104 (rank : 97)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	279	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH4_HUMAN
NC score	0.076002 (rank : 98)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	279	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

GSCR1_HUMAN
NC score	0.075789 (rank : 99)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	279	Target Neighborhood Hits	674	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

WIRE_HUMAN
NC score	0.075444 (rank : 100)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	279	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

MLL2_HUMAN
NC score	0.074278 (rank : 101)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	279	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BSN_MOUSE
NC score	0.074081 (rank : 102)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	279	Target Neighborhood Hits	2057	Shared Neighborhood Hits	148
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MLL3_HUMAN
NC score	0.073721 (rank : 103)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	279	Target Neighborhood Hits	1644	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FA47B_HUMAN
NC score	0.073603 (rank : 104)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	279	Target Neighborhood Hits	431	Shared Neighborhood Hits	96
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SON_HUMAN
NC score	0.073361 (rank : 105)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	279	Target Neighborhood Hits	1568	Shared Neighborhood Hits	155
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RGS3_MOUSE
NC score	0.073119 (rank : 106)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	279	Target Neighborhood Hits	1621	Shared Neighborhood Hits	161
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AB1IP_HUMAN
NC score	0.072767 (rank : 107)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	279	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

PRG4_MOUSE
NC score	0.072612 (rank : 108)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	279	Target Neighborhood Hits	624	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

IWS1_HUMAN
NC score	0.071830 (rank : 109)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	279	Target Neighborhood Hits	1241	Shared Neighborhood Hits	80
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NCOA6_MOUSE
NC score	0.070972 (rank : 110)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	279	Target Neighborhood Hits	1076	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

WASF1_MOUSE
NC score	0.070825 (rank : 111)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	279	Target Neighborhood Hits	261	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

MAGE1_HUMAN
NC score	0.070650 (rank : 112)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	279	Target Neighborhood Hits	1389	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MTMRD_HUMAN
NC score	0.070263 (rank : 113)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	279	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PRG4_HUMAN
NC score	0.069677 (rank : 114)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	279	Target Neighborhood Hits	764	Shared Neighborhood Hits	62
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

BCAR1_HUMAN
NC score	0.069612 (rank : 115)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	279	Target Neighborhood Hits	554	Shared Neighborhood Hits	97
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MLL3_MOUSE
NC score	0.069491 (rank : 116)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	279	Target Neighborhood Hits	1399	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

WASF2_HUMAN
NC score	0.069400 (rank : 117)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	279	Target Neighborhood Hits	280	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

MUC7_HUMAN
NC score	0.068938 (rank : 118)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	279	Target Neighborhood Hits	538	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

OGFR_HUMAN
NC score	0.068929 (rank : 119)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	279	Target Neighborhood Hits	1582	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCLO_MOUSE
NC score	0.068304 (rank : 120)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	279	Target Neighborhood Hits	2275	Shared Neighborhood Hits	164
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RASA3_HUMAN
NC score	0.067332 (rank : 121)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	279	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

BAT2_HUMAN
NC score	0.066990 (rank : 122)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	279	Target Neighborhood Hits	931	Shared Neighborhood Hits	93
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WASF2_MOUSE
NC score	0.066313 (rank : 123)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	279	Target Neighborhood Hits	315	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

RASA3_MOUSE
NC score	0.064759 (rank : 124)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	279	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RNC_HUMAN
NC score	0.064706 (rank : 125)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	279	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

PRR12_HUMAN
NC score	0.064164 (rank : 126)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	279	Target Neighborhood Hits	460	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

K1802_MOUSE
NC score	0.063805 (rank : 127)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	279	Target Neighborhood Hits	1596	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BCL9_MOUSE
NC score	0.063587 (rank : 128)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	279	Target Neighborhood Hits	770	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MINT_MOUSE
NC score	0.063430 (rank : 129)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	279	Target Neighborhood Hits	1514	Shared Neighborhood Hits	127
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BSN_HUMAN
NC score	0.063409 (rank : 130)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	279	Target Neighborhood Hits	1537	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

3BP1_HUMAN
NC score	0.063404 (rank : 131)	θ value	0.0148317 (rank : 30)
Query Neighborhood Hits	279	Target Neighborhood Hits	376	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TCF20_MOUSE
NC score	0.062446 (rank : 132)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	279	Target Neighborhood Hits	396	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

SF3A2_MOUSE
NC score	0.061976 (rank : 133)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	279	Target Neighborhood Hits	247	Shared Neighborhood Hits	33
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CBP_MOUSE
NC score	0.061682 (rank : 134)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	279	Target Neighborhood Hits	1051	Shared Neighborhood Hits	116
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

WIRE_MOUSE
NC score	0.061619 (rank : 135)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	279	Target Neighborhood Hits	310	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MISS_MOUSE
NC score	0.061587 (rank : 136)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	279	Target Neighborhood Hits	444	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

LR37A_HUMAN
NC score	0.061299 (rank : 137)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	279	Target Neighborhood Hits	720	Shared Neighborhood Hits	81
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

TCGAP_HUMAN
NC score	0.060792 (rank : 138)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	279	Target Neighborhood Hits	872	Shared Neighborhood Hits	120
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BLNK_HUMAN
NC score	0.060493 (rank : 139)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CEL_HUMAN
NC score	0.060473 (rank : 140)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	279	Target Neighborhood Hits	896	Shared Neighborhood Hits	130
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CD2_HUMAN
NC score	0.060361 (rank : 141)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	279	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

RGS3_HUMAN
NC score	0.059707 (rank : 142)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	279	Target Neighborhood Hits	1375	Shared Neighborhood Hits	158
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

3BP2_MOUSE
NC score	0.059547 (rank : 143)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	279	Target Neighborhood Hits	142	Shared Neighborhood Hits	29
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

RBM16_HUMAN
NC score	0.059031 (rank : 144)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	279	Target Neighborhood Hits	300	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RTP3_MOUSE
NC score	0.058957 (rank : 145)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	279	Target Neighborhood Hits	374	Shared Neighborhood Hits	74
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TXND2_HUMAN
NC score	0.058789 (rank : 146)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	279	Target Neighborhood Hits	793	Shared Neighborhood Hits	88
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SETBP_MOUSE
NC score	0.058526 (rank : 147)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	279	Target Neighborhood Hits	352	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

OSBP1_HUMAN
NC score	0.058470 (rank : 148)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	279	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

LPP_HUMAN
NC score	0.058425 (rank : 149)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	279	Target Neighborhood Hits	775	Shared Neighborhood Hits	106
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

BTG3_HUMAN
NC score	0.058255 (rank : 150)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	279	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q14201, Q96ET7	Gene names	BTG3, ANA, TOB5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

CF055_MOUSE
NC score	0.058053 (rank : 151)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	279	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

DGKH_HUMAN
NC score	0.057903 (rank : 152)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	279	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

BCAR1_MOUSE
NC score	0.057502 (rank : 153)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	279	Target Neighborhood Hits	438	Shared Neighborhood Hits	79
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CEND3_HUMAN
NC score	0.056835 (rank : 154)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	279	Target Neighborhood Hits	275	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

IASPP_MOUSE
NC score	0.056212 (rank : 155)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	279	Target Neighborhood Hits	1024	Shared Neighborhood Hits	102
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CO039_MOUSE
NC score	0.056136 (rank : 156)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	279	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

UBP2L_HUMAN
NC score	0.056028 (rank : 157)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	279	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ATN1_HUMAN
NC score	0.055852 (rank : 158)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	279	Target Neighborhood Hits	676	Shared Neighborhood Hits	61
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SELPL_MOUSE
NC score	0.055821 (rank : 159)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	279	Target Neighborhood Hits	588	Shared Neighborhood Hits	75
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ALEX_HUMAN
NC score	0.055796 (rank : 160)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	279	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

DDEF1_MOUSE
NC score	0.055417 (rank : 161)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	279	Target Neighborhood Hits	592	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

OSBP2_MOUSE
NC score	0.055388 (rank : 162)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	279	Target Neighborhood Hits	150	Shared Neighborhood Hits	42
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PDCD7_MOUSE
NC score	0.055374 (rank : 163)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	279	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

AF9_HUMAN
NC score	0.054695 (rank : 164)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	279	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CS007_MOUSE
NC score	0.054679 (rank : 165)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	279	Target Neighborhood Hits	464	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CCNK_MOUSE
NC score	0.054667 (rank : 166)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	279	Target Neighborhood Hits	350	Shared Neighborhood Hits	44
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CEND3_MOUSE
NC score	0.054614 (rank : 167)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

PI5PA_HUMAN
NC score	0.054355 (rank : 168)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	279	Target Neighborhood Hits	749	Shared Neighborhood Hits	103
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SF3A2_HUMAN
NC score	0.054321 (rank : 169)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	279	Target Neighborhood Hits	263	Shared Neighborhood Hits	32
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PININ_HUMAN
NC score	0.054144 (rank : 170)	θ value	0.0148317 (rank : 32)
Query Neighborhood Hits	279	Target Neighborhood Hits	753	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

GNAS3_HUMAN
NC score	0.053955 (rank : 171)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	279	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

ENAH_MOUSE
NC score	0.053488 (rank : 172)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	279	Target Neighborhood Hits	919	Shared Neighborhood Hits	67
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FYB_HUMAN
NC score	0.053381 (rank : 173)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	279	Target Neighborhood Hits	379	Shared Neighborhood Hits	48
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

BRD4_MOUSE
NC score	0.053366 (rank : 174)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	279	Target Neighborhood Hits	845	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SYNJ1_HUMAN
NC score	0.053352 (rank : 175)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	279	Target Neighborhood Hits	498	Shared Neighborhood Hits	77
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MAP4_MOUSE
NC score	0.053203 (rank : 176)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	45
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ARI1A_HUMAN
NC score	0.052928 (rank : 177)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	279	Target Neighborhood Hits	787	Shared Neighborhood Hits	82
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NOLC1_HUMAN
NC score	0.052736 (rank : 178)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	279	Target Neighborhood Hits	452	Shared Neighborhood Hits	37
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BTG3_MOUSE
NC score	0.052672 (rank : 179)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	279	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P50615, Q62328	Gene names	Btg3, Ana, Tob5
Domain Architecture
Description	BTG3 protein (Tob5 protein) (Abundant in neuroepithelium area protein).

SPR1B_MOUSE
NC score	0.052656 (rank : 180)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	279	Target Neighborhood Hits	395	Shared Neighborhood Hits	83
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

ATX2_MOUSE
NC score	0.052576 (rank : 181)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	279	Target Neighborhood Hits	445	Shared Neighborhood Hits	73
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

TAF4_HUMAN
NC score	0.052499 (rank : 182)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	279	Target Neighborhood Hits	687	Shared Neighborhood Hits	58
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MLL4_HUMAN
NC score	0.052049 (rank : 183)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	279	Target Neighborhood Hits	722	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

OSBL9_HUMAN
NC score	0.052033 (rank : 184)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	279	Target Neighborhood Hits	138	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

TGON2_HUMAN
NC score	0.051993 (rank : 185)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	279	Target Neighborhood Hits	1037	Shared Neighborhood Hits	83
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

IWS1_MOUSE
NC score	0.051901 (rank : 186)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	279	Target Neighborhood Hits	1258	Shared Neighborhood Hits	96
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NFH_MOUSE
NC score	0.051635 (rank : 187)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	279	Target Neighborhood Hits	2247	Shared Neighborhood Hits	143
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CENA2_HUMAN
NC score	0.051273 (rank : 188)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	279	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

NCOR2_HUMAN
NC score	0.050784 (rank : 189)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	279	Target Neighborhood Hits	870	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ZIM10_HUMAN
NC score	0.050690 (rank : 190)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	279	Target Neighborhood Hits	577	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CK024_HUMAN
NC score	0.050637 (rank : 191)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	279	Target Neighborhood Hits	408	Shared Neighborhood Hits	64
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SYNJ1_MOUSE
NC score	0.050605 (rank : 192)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	279	Target Neighborhood Hits	516	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

OSBL3_MOUSE
NC score	0.050433 (rank : 193)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	279	Target Neighborhood Hits	86	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

SHAN1_HUMAN
NC score	0.050433 (rank : 194)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	279	Target Neighborhood Hits	1041	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PKHB2_MOUSE
NC score	0.050368 (rank : 195)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	279	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

CBP_HUMAN
NC score	0.050265 (rank : 196)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	279	Target Neighborhood Hits	941	Shared Neighborhood Hits	100
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENA2_MOUSE
NC score	0.050131 (rank : 197)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	279	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

BAT2_MOUSE
NC score	0.050114 (rank : 198)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	279	Target Neighborhood Hits	947	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WASP_HUMAN
NC score	0.050015 (rank : 199)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	279	Target Neighborhood Hits	195	Shared Neighborhood Hits	28
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

CJ078_MOUSE
NC score	0.049840 (rank : 200)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	279	Target Neighborhood Hits	559	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

OSBL3_HUMAN
NC score	0.049647 (rank : 201)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	279	Target Neighborhood Hits	93	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

DREB_MOUSE
NC score	0.048836 (rank : 202)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	279	Target Neighborhood Hits	446	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DOT1L_HUMAN
NC score	0.048804 (rank : 203)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	279	Target Neighborhood Hits	660	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GP158_HUMAN
NC score	0.047995 (rank : 204)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	279	Target Neighborhood Hits	221	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

MUC2_HUMAN
NC score	0.046830 (rank : 205)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	279	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TAF3_MOUSE
NC score	0.046613 (rank : 206)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	279	Target Neighborhood Hits	463	Shared Neighborhood Hits	33
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

HRX_HUMAN
NC score	0.046334 (rank : 207)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	279	Target Neighborhood Hits	825	Shared Neighborhood Hits	69
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TCF20_HUMAN
NC score	0.046150 (rank : 208)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	279	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

EP300_HUMAN
NC score	0.045807 (rank : 209)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	279	Target Neighborhood Hits	821	Shared Neighborhood Hits	71
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MNT_HUMAN
NC score	0.044685 (rank : 210)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	279	Target Neighborhood Hits	496	Shared Neighborhood Hits	69
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

AP180_MOUSE
NC score	0.044178 (rank : 211)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	279	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

DIAP1_HUMAN
NC score	0.044177 (rank : 212)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	279	Target Neighborhood Hits	784	Shared Neighborhood Hits	46
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

BAT3_MOUSE
NC score	0.043561 (rank : 213)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	279	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

ZCHC8_MOUSE
NC score	0.043231 (rank : 214)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	279	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

BRD4_HUMAN
NC score	0.042383 (rank : 215)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	279	Target Neighborhood Hits	851	Shared Neighborhood Hits	72
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

ZYX_HUMAN
NC score	0.041823 (rank : 216)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	279	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

DPOD3_HUMAN
NC score	0.041431 (rank : 217)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	279	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

CRTC1_HUMAN
NC score	0.040330 (rank : 218)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	279	Target Neighborhood Hits	319	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FMN2_HUMAN
NC score	0.040066 (rank : 219)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	279	Target Neighborhood Hits	484	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

YLPM1_MOUSE
NC score	0.039932 (rank : 220)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	279	Target Neighborhood Hits	505	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ERRFI_MOUSE
NC score	0.039551 (rank : 221)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	279	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

CTDP1_MOUSE
NC score	0.039408 (rank : 222)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	279	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

FHOD1_MOUSE
NC score	0.039318 (rank : 223)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	279	Target Neighborhood Hits	217	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

REXO1_HUMAN
NC score	0.039036 (rank : 224)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	279	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SHAN2_MOUSE
NC score	0.038913 (rank : 225)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	279	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SF01_HUMAN
NC score	0.038906 (rank : 226)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	279	Target Neighborhood Hits	287	Shared Neighborhood Hits	43
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

CF055_HUMAN
NC score	0.038718 (rank : 227)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	279	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

MYCB2_HUMAN
NC score	0.038606 (rank : 228)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	279	Target Neighborhood Hits	390	Shared Neighborhood Hits	28
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RBBP6_HUMAN
NC score	0.038122 (rank : 229)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	279	Target Neighborhood Hits	1135	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

OSBL6_MOUSE
NC score	0.036870 (rank : 230)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	279	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

SFPQ_MOUSE
NC score	0.036753 (rank : 231)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	279	Target Neighborhood Hits	958	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CABYR_MOUSE
NC score	0.036577 (rank : 232)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	279	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

OSBL6_HUMAN
NC score	0.036533 (rank : 233)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	279	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

HNRL1_MOUSE
NC score	0.036525 (rank : 234)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	279	Target Neighborhood Hits	200	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

S23IP_HUMAN
NC score	0.036270 (rank : 235)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	279	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

ENAH_HUMAN
NC score	0.035705 (rank : 236)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	279	Target Neighborhood Hits	784	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

APC_HUMAN
NC score	0.034895 (rank : 237)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	279	Target Neighborhood Hits	603	Shared Neighborhood Hits	51
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PO121_HUMAN
NC score	0.034851 (rank : 238)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	279	Target Neighborhood Hits	344	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RBBP6_MOUSE
NC score	0.034648 (rank : 239)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	279	Target Neighborhood Hits	1014	Shared Neighborhood Hits	57
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SF01_MOUSE
NC score	0.034028 (rank : 240)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	279	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

PHF3_HUMAN
NC score	0.033525 (rank : 241)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	279	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ZYX_MOUSE
NC score	0.033523 (rank : 242)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	279	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

GAK6_HUMAN
NC score	0.033075 (rank : 243)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	279	Target Neighborhood Hits	392	Shared Neighborhood Hits	91
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.032949 (rank : 244)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	279	Target Neighborhood Hits	415	Shared Neighborhood Hits	95
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.032864 (rank : 245)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	279	Target Neighborhood Hits	406	Shared Neighborhood Hits	95
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PTN23_HUMAN
NC score	0.032784 (rank : 246)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	279	Target Neighborhood Hits	646	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

GAK11_HUMAN
NC score	0.032778 (rank : 247)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	279	Target Neighborhood Hits	409	Shared Neighborhood Hits	94
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

BAI1_HUMAN
NC score	0.032617 (rank : 248)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	279	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MYST3_MOUSE
NC score	0.031752 (rank : 249)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	279	Target Neighborhood Hits	688	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

DREB_HUMAN
NC score	0.031594 (rank : 250)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	279	Target Neighborhood Hits	450	Shared Neighborhood Hits	26
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SOS2_HUMAN
NC score	0.031401 (rank : 251)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	279	Target Neighborhood Hits	193	Shared Neighborhood Hits	23
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

DAB2_MOUSE
NC score	0.030737 (rank : 252)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	279	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

GAK12_HUMAN
NC score	0.030568 (rank : 253)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	279	Target Neighborhood Hits	374	Shared Neighborhood Hits	90
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ABI3_HUMAN
NC score	0.030254 (rank : 254)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	279	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

BAI1_MOUSE
NC score	0.030164 (rank : 255)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	279	Target Neighborhood Hits	340	Shared Neighborhood Hits	27
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CD2AP_HUMAN
NC score	0.030117 (rank : 256)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	279	Target Neighborhood Hits	315	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CJ026_MOUSE
NC score	0.030020 (rank : 257)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	279	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

ZO1_MOUSE
NC score	0.029940 (rank : 258)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	279	Target Neighborhood Hits	453	Shared Neighborhood Hits	38
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PDC6I_MOUSE
NC score	0.028862 (rank : 259)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	279	Target Neighborhood Hits	275	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

BMX_HUMAN
NC score	0.028578 (rank : 260)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	279	Target Neighborhood Hits	942	Shared Neighborhood Hits	43
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

FBLI1_MOUSE
NC score	0.027849 (rank : 261)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	279	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

BMX_MOUSE
NC score	0.027156 (rank : 262)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	279	Target Neighborhood Hits	912	Shared Neighborhood Hits	42
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

PTN23_MOUSE
NC score	0.026804 (rank : 263)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	279	Target Neighborhood Hits	726	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

NGAP_HUMAN
NC score	0.026740 (rank : 264)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	279	Target Neighborhood Hits	517	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

CN092_MOUSE
NC score	0.026486 (rank : 265)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	279	Target Neighborhood Hits	206	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

EVI2B_MOUSE
NC score	0.026327 (rank : 266)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

POLS_MOUSE
NC score	0.025966 (rank : 267)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	279	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

SPEG_MOUSE
NC score	0.025276 (rank : 268)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	279	Target Neighborhood Hits	1959	Shared Neighborhood Hits	124
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

HUWE1_MOUSE
NC score	0.025091 (rank : 269)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	279	Target Neighborhood Hits	406	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

ARHG7_MOUSE
NC score	0.024986 (rank : 270)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	279	Target Neighborhood Hits	396	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

STX17_HUMAN
NC score	0.024801 (rank : 271)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	279	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P56962	Gene names	STX17
Domain Architecture
Description	Syntaxin-17 (KAT01814).

ABI3_MOUSE
NC score	0.024607 (rank : 272)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	279	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

HUWE1_HUMAN
NC score	0.023788 (rank : 273)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	279	Target Neighborhood Hits	443	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

SCAM3_HUMAN
NC score	0.022948 (rank : 274)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	279	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	O14828, O15128, Q96FR8, Q9BPY0	Gene names	SCAMP3, PROPIN1
Domain Architecture
Description	Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3).

ACK1_HUMAN
NC score	0.022657 (rank : 275)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	279	Target Neighborhood Hits	1140	Shared Neighborhood Hits	88
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

PKP4_HUMAN
NC score	0.022444 (rank : 276)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	279	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

EHMT2_MOUSE
NC score	0.022199 (rank : 277)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	279	Target Neighborhood Hits	750	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

STP2_HUMAN
NC score	0.021903 (rank : 278)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	279	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q05952, Q9NZB0	Gene names	TNP2
Domain Architecture
Description	Nuclear transition protein 2 (TP-2) (TP2).

CBL_HUMAN
NC score	0.021903 (rank : 279)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	279	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

PTCD1_HUMAN
NC score	0.021568 (rank : 280)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	279	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

TM55A_HUMAN
NC score	0.021261 (rank : 281)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	279	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N4L2, Q68CU2	Gene names	TMEM55A
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

ACK1_MOUSE
NC score	0.021070 (rank : 282)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	279	Target Neighborhood Hits	1080	Shared Neighborhood Hits	79
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

LRP6_MOUSE
NC score	0.020635 (rank : 283)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	279	Target Neighborhood Hits	232	Shared Neighborhood Hits	8
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_HUMAN
NC score	0.020146 (rank : 284)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	279	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

FBLI1_HUMAN
NC score	0.020084 (rank : 285)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	279	Target Neighborhood Hits	200	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

CJ047_HUMAN
NC score	0.019783 (rank : 286)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	279	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

DIAP2_HUMAN
NC score	0.019124 (rank : 287)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	279	Target Neighborhood Hits	342	Shared Neighborhood Hits	23
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

CBLB_HUMAN
NC score	0.019049 (rank : 288)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	279	Target Neighborhood Hits	261	Shared Neighborhood Hits	23
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

TM55A_MOUSE
NC score	0.018726 (rank : 289)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	279	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZX7	Gene names	Tmem55a
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55A (EC 3.1.3.-) (Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase II).

SYNJ2_MOUSE
NC score	0.018468 (rank : 290)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	279	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

CAC1A_HUMAN
NC score	0.018200 (rank : 291)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	279	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

HECD1_HUMAN
NC score	0.018058 (rank : 292)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	279	Target Neighborhood Hits	371	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

TTP_MOUSE
NC score	0.016967 (rank : 293)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	279	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

TREF1_MOUSE
NC score	0.016747 (rank : 294)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	279	Target Neighborhood Hits	682	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

PCD15_HUMAN
NC score	0.016746 (rank : 295)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	279	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

NECD_HUMAN
NC score	0.015985 (rank : 296)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	279	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

SYTL2_HUMAN
NC score	0.015522 (rank : 297)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	279	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

ST5_HUMAN
NC score	0.015509 (rank : 298)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	279	Target Neighborhood Hits	151	Shared Neighborhood Hits	23
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

RT18A_HUMAN
NC score	0.015345 (rank : 299)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	279	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVS2	Gene names	MRPS18A
Domain Architecture
Description	28S ribosomal protein S18a, mitochondrial precursor (MRP-S18-a) (Mrps18a) (MRP-S18-3).

DAXX_MOUSE
NC score	0.015018 (rank : 300)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	279	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

TITIN_HUMAN
NC score	0.014678 (rank : 301)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	279	Target Neighborhood Hits	2923	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CAC1A_MOUSE
NC score	0.014626 (rank : 302)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	279	Target Neighborhood Hits	267	Shared Neighborhood Hits	25
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

WNK4_HUMAN
NC score	0.014552 (rank : 303)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	279	Target Neighborhood Hits	1043	Shared Neighborhood Hits	43
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TBCD5_HUMAN
NC score	0.014408 (rank : 304)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	279	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

WNK2_HUMAN
NC score	0.013943 (rank : 305)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	279	Target Neighborhood Hits	1407	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

LAP2_HUMAN
NC score	0.013725 (rank : 306)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	279	Target Neighborhood Hits	499	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PAPOG_MOUSE
NC score	0.013640 (rank : 307)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	279	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

ROBO4_HUMAN
NC score	0.013150 (rank : 308)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	279	Target Neighborhood Hits	364	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

CELR3_HUMAN
NC score	0.012551 (rank : 309)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	279	Target Neighborhood Hits	680	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

PTN13_MOUSE
NC score	0.012091 (rank : 310)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	279	Target Neighborhood Hits	426	Shared Neighborhood Hits	20
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

CMTA2_MOUSE
NC score	0.011907 (rank : 311)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	279	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

AIPL1_HUMAN
NC score	0.011695 (rank : 312)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	279	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

LTBP4_MOUSE
NC score	0.011083 (rank : 313)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	279	Target Neighborhood Hits	607	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

RBL2_MOUSE
NC score	0.011082 (rank : 314)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	279	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q64700	Gene names	Rbl2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

SN1L2_MOUSE
NC score	0.010678 (rank : 315)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	279	Target Neighborhood Hits	944	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

ABHD5_HUMAN
NC score	0.010414 (rank : 316)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	279	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTS1, Q9Y369	Gene names	ABHD5, NCIE2
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5.

SMAD2_MOUSE
NC score	0.010237 (rank : 317)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	279	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SMAD2_HUMAN
NC score	0.010236 (rank : 318)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	279	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

KLF10_MOUSE
NC score	0.009340 (rank : 319)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	279	Target Neighborhood Hits	741	Shared Neighborhood Hits	18
SwissProt Accessions	O89091	Gene names	Klf10, Gdnfif, Tieg, Tieg1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (GDNF-inducible factor) (Transcription factor GIF) (mGIF).

M3K11_HUMAN
NC score	0.009005 (rank : 320)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	279	Target Neighborhood Hits	1136	Shared Neighborhood Hits	45
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PCD16_HUMAN
NC score	0.008887 (rank : 321)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	279	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

CTBP1_HUMAN
NC score	0.008736 (rank : 322)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	279	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

ZEP1_HUMAN
NC score	0.008258 (rank : 323)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	279	Target Neighborhood Hits	1036	Shared Neighborhood Hits	59
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

BOC_MOUSE
NC score	0.007885 (rank : 324)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	279	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

TRPS1_MOUSE
NC score	0.007808 (rank : 325)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	279	Target Neighborhood Hits	609	Shared Neighborhood Hits	12
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

PGBM_HUMAN
NC score	0.007758 (rank : 326)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	279	Target Neighborhood Hits	1113	Shared Neighborhood Hits	19
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KSR2_HUMAN
NC score	0.007389 (rank : 327)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	279	Target Neighborhood Hits	920	Shared Neighborhood Hits	33
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

EPS8_MOUSE
NC score	0.007274 (rank : 328)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	279	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

XK_HUMAN
NC score	0.007004 (rank : 329)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	279	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P51811, Q4TTN6, Q8IUK6, Q9UC77	Gene names	XK, XKR1, XRG1
Domain Architecture	No domain graphic available
Description	Membrane transport protein XK (Kx antigen) (Kell complex 37 kDa component) (XK-related protein 1).

KLF2_MOUSE
NC score	0.006528 (rank : 330)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	279	Target Neighborhood Hits	738	Shared Neighborhood Hits	12
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

EGR2_MOUSE
NC score	0.006281 (rank : 331)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	279	Target Neighborhood Hits	745	Shared Neighborhood Hits	19
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

KLF10_HUMAN
NC score	0.005004 (rank : 332)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	279	Target Neighborhood Hits	744	Shared Neighborhood Hits	16
SwissProt Accessions	Q13118	Gene names	KLF10, TIEG, TIEG1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (EGR-alpha).

HXB4_HUMAN
NC score	0.004822 (rank : 333)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	279	Target Neighborhood Hits	376	Shared Neighborhood Hits	11
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

HXB4_MOUSE
NC score	0.003799 (rank : 334)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	279	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

HNF3A_MOUSE
NC score	0.002240 (rank : 335)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	279	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	P35582, Q61108	Gene names	Foxa1, Hnf3a, Tcf-3a, Tcf3a
Domain Architecture
Description	Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1).

PCTK2_HUMAN
NC score	0.001959 (rank : 336)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	279	Target Neighborhood Hits	837	Shared Neighborhood Hits	14
SwissProt Accessions	Q00537, Q8NEB8	Gene names	PCTK2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

PCTK2_MOUSE
NC score	0.001594 (rank : 337)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	279	Target Neighborhood Hits	836	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K0D0	Gene names	Pctk2
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 2).

DRD2_MOUSE
NC score	0.000555 (rank : 338)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	279	Target Neighborhood Hits	779	Shared Neighborhood Hits	10
SwissProt Accessions	P61168, P13953	Gene names	Drd2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

ZBT45_HUMAN
NC score	-0.000041 (rank : 339)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	279	Target Neighborhood Hits	901	Shared Neighborhood Hits	30
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

HIC1_MOUSE
NC score	-0.000759 (rank : 340)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	279	Target Neighborhood Hits	863	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

HIC1_HUMAN
NC score	-0.001495 (rank : 341)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	279	Target Neighborhood Hits	838	Shared Neighborhood Hits	14
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).