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Network neighborhood for query Sequence : ERRFI_MOUSE

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ERRFI_MOUSE
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERRFI_HUMAN
θ value	0 (rank : 1)	NC score	0.976022 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

ERRFI_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

ACK1_HUMAN
θ value	1.47289e-26 (rank : 3)	NC score	0.136618 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	1140	Shared Neighborhood Hits	26
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	1.92365e-26 (rank : 4)	NC score	0.137024 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	1080	Shared Neighborhood Hits	23
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

RAPH1_HUMAN
θ value	0.00509761 (rank : 5)	NC score	0.106168 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	593	Shared Neighborhood Hits	33
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PCLO_HUMAN
θ value	0.0961366 (rank : 6)	NC score	0.056152 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	2046	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ZN750_MOUSE
θ value	0.125558 (rank : 7)	NC score	0.105574 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ANK2_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.028197 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	1615	Shared Neighborhood Hits	30
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

XRCC1_MOUSE
θ value	0.21417 (rank : 9)	NC score	0.072051 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

IASPP_MOUSE
θ value	0.279714 (rank : 10)	NC score	0.040193 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	1024	Shared Neighborhood Hits	27
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K0310_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.109336 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	420	Shared Neighborhood Hits	15
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

SRRM2_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.060820 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	1296	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ADA15_MOUSE
θ value	0.365318 (rank : 13)	NC score	0.020434 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

CG1_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.073620 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

NACAM_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.063692 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	1866	Shared Neighborhood Hits	49
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MYH6_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.013964 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	1501	Shared Neighborhood Hits	13
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CDCA5_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.062325 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CPY3, Q78HI6	Gene names	Cdca5
Domain Architecture	No domain graphic available
Description	Sororin (Cell division cycle-associated protein 5).

CF055_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.062759 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

KCNQ2_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.022044 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	163	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

DSCL1_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.009793 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	589	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

HRX_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.036314 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	825	Shared Neighborhood Hits	21
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

RERE_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.033446 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SSH2_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.028507 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

WNK3_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.018420 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	948	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

BCL6_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.002216 (rank : 74)
Query Neighborhood Hits	72	Target Neighborhood Hits	913	Shared Neighborhood Hits	13
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BSN_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.049602 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	2057	Shared Neighborhood Hits	37
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CEP68_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.035050 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

GSCR1_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.058098 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	674	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

JIP3_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.018700 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MYH6_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.011809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	1426	Shared Neighborhood Hits	11
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYST3_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.028744 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	772	Shared Neighborhood Hits	20
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

REPS2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.037028 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS2_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.036846 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

TS13_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.043182 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

AL2SB_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.038371 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	294	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

EYA4_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.022467 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

ATX1_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.057445 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

LCP2_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.043631 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LRP5_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.009106 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MTG8R_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.043280 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

RFIP4_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.017767 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	785	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SEM6B_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.008726 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SETD8_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.026567 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

YLPM1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.058529 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	670	Shared Neighborhood Hits	23
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

DAB2P_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.016922 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DDEF1_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.015180 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

FGD1_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.014343 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MYCB2_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.019189 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	390	Shared Neighborhood Hits	11
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TROAP_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.035311 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	258	Shared Neighborhood Hits	13
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

CD248_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.027720 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	679	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DKK3_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.016938 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

EYA4_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.019874 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

GAB1_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.044548 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MTG8R_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.038262 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

RFX1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.037418 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	256	Shared Neighborhood Hits	14
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SRRM1_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.059856 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	966	Shared Neighborhood Hits	42
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ATX1_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.054983 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CDCA5_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.041578 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q96FF9	Gene names	CDCA5
Domain Architecture	No domain graphic available
Description	Sororin (Cell division cycle-associated protein 5) (p35).

CJ078_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.050122 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

DPOLA_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.011507 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DUS3L_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.012748 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

FGD1_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.013583 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FMNL_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.034070 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	529	Shared Neighborhood Hits	17
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GAB1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.039551 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	279	Shared Neighborhood Hits	21
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

M3K9_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.026240 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	1123	Shared Neighborhood Hits	14
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MAGC3_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.009055 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

NECD_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.016986 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

PSL1_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.058421 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RTN4_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.042950 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	357	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SHAN1_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.022787 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SOS1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.018747 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	274	Shared Neighborhood Hits	15
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.017413 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

MDC1_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.055220 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

WASIP_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.060129 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

Hits sorted by NC score

ERRFI_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

ERRFI_HUMAN
NC score	0.976022 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

ACK1_MOUSE
NC score	0.137024 (rank : 3)	θ value	1.92365e-26 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	1080	Shared Neighborhood Hits	23
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ACK1_HUMAN
NC score	0.136618 (rank : 4)	θ value	1.47289e-26 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	1140	Shared Neighborhood Hits	26
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

K0310_HUMAN
NC score	0.109336 (rank : 5)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	420	Shared Neighborhood Hits	15
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

RAPH1_HUMAN
NC score	0.106168 (rank : 6)	θ value	0.00509761 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	593	Shared Neighborhood Hits	33
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

ZN750_MOUSE
NC score	0.105574 (rank : 7)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CG1_HUMAN
NC score	0.073620 (rank : 8)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

XRCC1_MOUSE
NC score	0.072051 (rank : 9)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

NACAM_MOUSE
NC score	0.063692 (rank : 10)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	1866	Shared Neighborhood Hits	49
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CF055_HUMAN
NC score	0.062759 (rank : 11)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

CDCA5_MOUSE
NC score	0.062325 (rank : 12)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CPY3, Q78HI6	Gene names	Cdca5
Domain Architecture	No domain graphic available
Description	Sororin (Cell division cycle-associated protein 5).

SRRM2_HUMAN
NC score	0.060820 (rank : 13)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	1296	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WASIP_MOUSE
NC score	0.060129 (rank : 14)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	72	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SRRM1_MOUSE
NC score	0.059856 (rank : 15)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	966	Shared Neighborhood Hits	42
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

YLPM1_HUMAN
NC score	0.058529 (rank : 16)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	670	Shared Neighborhood Hits	23
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PSL1_HUMAN
NC score	0.058421 (rank : 17)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

GSCR1_HUMAN
NC score	0.058098 (rank : 18)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	674	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

ATX1_HUMAN
NC score	0.057445 (rank : 19)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

PCLO_HUMAN
NC score	0.056152 (rank : 20)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	2046	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MDC1_MOUSE
NC score	0.055220 (rank : 21)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ATX1_MOUSE
NC score	0.054983 (rank : 22)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CJ078_MOUSE
NC score	0.050122 (rank : 23)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

BSN_MOUSE
NC score	0.049602 (rank : 24)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	2057	Shared Neighborhood Hits	37
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GAB1_MOUSE
NC score	0.044548 (rank : 25)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

LCP2_HUMAN
NC score	0.043631 (rank : 26)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MTG8R_HUMAN
NC score	0.043280 (rank : 27)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

TS13_MOUSE
NC score	0.043182 (rank : 28)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

RTN4_HUMAN
NC score	0.042950 (rank : 29)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	357	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CDCA5_HUMAN
NC score	0.041578 (rank : 30)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q96FF9	Gene names	CDCA5
Domain Architecture	No domain graphic available
Description	Sororin (Cell division cycle-associated protein 5) (p35).

IASPP_MOUSE
NC score	0.040193 (rank : 31)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	1024	Shared Neighborhood Hits	27
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GAB1_HUMAN
NC score	0.039551 (rank : 32)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	279	Shared Neighborhood Hits	21
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

AL2SB_HUMAN
NC score	0.038371 (rank : 33)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	294	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

MTG8R_MOUSE
NC score	0.038262 (rank : 34)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

RFX1_HUMAN
NC score	0.037418 (rank : 35)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	256	Shared Neighborhood Hits	14
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

REPS2_HUMAN
NC score	0.037028 (rank : 36)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS2_MOUSE
NC score	0.036846 (rank : 37)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

HRX_HUMAN
NC score	0.036314 (rank : 38)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	825	Shared Neighborhood Hits	21
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TROAP_HUMAN
NC score	0.035311 (rank : 39)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	258	Shared Neighborhood Hits	13
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

CEP68_HUMAN
NC score	0.035050 (rank : 40)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

FMNL_HUMAN
NC score	0.034070 (rank : 41)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	529	Shared Neighborhood Hits	17
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

RERE_MOUSE
NC score	0.033446 (rank : 42)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MYST3_HUMAN
NC score	0.028744 (rank : 43)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	772	Shared Neighborhood Hits	20
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

SSH2_HUMAN
NC score	0.028507 (rank : 44)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

ANK2_HUMAN
NC score	0.028197 (rank : 45)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	1615	Shared Neighborhood Hits	30
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CD248_HUMAN
NC score	0.027720 (rank : 46)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	679	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SETD8_MOUSE
NC score	0.026567 (rank : 47)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

M3K9_HUMAN
NC score	0.026240 (rank : 48)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	1123	Shared Neighborhood Hits	14
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

SHAN1_HUMAN
NC score	0.022787 (rank : 49)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

EYA4_MOUSE
NC score	0.022467 (rank : 50)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

KCNQ2_MOUSE
NC score	0.022044 (rank : 51)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	163	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

ADA15_MOUSE
NC score	0.020434 (rank : 52)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

EYA4_HUMAN
NC score	0.019874 (rank : 53)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

MYCB2_HUMAN
NC score	0.019189 (rank : 54)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	390	Shared Neighborhood Hits	11
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SOS1_HUMAN
NC score	0.018747 (rank : 55)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	274	Shared Neighborhood Hits	15
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

JIP3_MOUSE
NC score	0.018700 (rank : 56)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

WNK3_HUMAN
NC score	0.018420 (rank : 57)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	948	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

RFIP4_HUMAN
NC score	0.017767 (rank : 58)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	785	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SOS1_MOUSE
NC score	0.017413 (rank : 59)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

NECD_HUMAN
NC score	0.016986 (rank : 60)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

DKK3_HUMAN
NC score	0.016938 (rank : 61)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DAB2P_HUMAN
NC score	0.016922 (rank : 62)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DDEF1_MOUSE
NC score	0.015180 (rank : 63)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

FGD1_HUMAN
NC score	0.014343 (rank : 64)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MYH6_MOUSE
NC score	0.013964 (rank : 65)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	1501	Shared Neighborhood Hits	13
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

FGD1_MOUSE
NC score	0.013583 (rank : 66)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

DUS3L_HUMAN
NC score	0.012748 (rank : 67)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

MYH6_HUMAN
NC score	0.011809 (rank : 68)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	1426	Shared Neighborhood Hits	11
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

DPOLA_HUMAN
NC score	0.011507 (rank : 69)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DSCL1_HUMAN
NC score	0.009793 (rank : 70)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	589	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

LRP5_HUMAN
NC score	0.009106 (rank : 71)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MAGC3_HUMAN
NC score	0.009055 (rank : 72)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

SEM6B_MOUSE
NC score	0.008726 (rank : 73)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

BCL6_MOUSE
NC score	0.002216 (rank : 74)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	913	Shared Neighborhood Hits	13
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.