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Network neighborhood for query Sequence : EYA4_HUMAN

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EYA4_HUMAN
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EYA1_HUMAN
θ value	0 (rank : 1)	NC score	0.970248 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA1_MOUSE
θ value	0 (rank : 2)	NC score	0.969381 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA4_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_MOUSE
θ value	0 (rank : 4)	NC score	0.991348 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA2_HUMAN
θ value	3.47952e-169 (rank : 5)	NC score	0.970280 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA2_MOUSE
θ value	3.84704e-168 (rank : 6)	NC score	0.971330 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA3_HUMAN
θ value	1.01709e-152 (rank : 7)	NC score	0.966193 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_MOUSE
θ value	1.01945e-144 (rank : 8)	NC score	0.966820 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

RPB1_HUMAN
θ value	2.44474e-05 (rank : 9)	NC score	0.109472 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	362	Shared Neighborhood Hits	22
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	2.44474e-05 (rank : 10)	NC score	0.109459 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	363	Shared Neighborhood Hits	22
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

NU153_HUMAN
θ value	0.000602161 (rank : 11)	NC score	0.074300 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

MCM3A_HUMAN
θ value	0.00298849 (rank : 12)	NC score	0.090168 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

ARI1A_HUMAN
θ value	0.00869519 (rank : 13)	NC score	0.062327 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	787	Shared Neighborhood Hits	32
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MCM3A_MOUSE
θ value	0.00869519 (rank : 14)	NC score	0.101839 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

FUS_MOUSE
θ value	0.0193708 (rank : 15)	NC score	0.138822 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

MAML3_HUMAN
θ value	0.0193708 (rank : 16)	NC score	0.063864 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

EGR1_MOUSE
θ value	0.0330416 (rank : 17)	NC score	0.009761 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	816	Shared Neighborhood Hits	19
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

EWS_MOUSE
θ value	0.0330416 (rank : 18)	NC score	0.130986 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

SMG7_HUMAN
θ value	0.0431538 (rank : 19)	NC score	0.052149 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

NFAC3_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.040275 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PEPC_HUMAN
θ value	0.0563607 (rank : 21)	NC score	0.032110 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P20142, Q5T3D7, Q5T3D8	Gene names	PGC
Domain Architecture
Description	Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).

TFG_HUMAN
θ value	0.0563607 (rank : 22)	NC score	0.087691 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

ELN_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.034507 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

PUM2_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.079182 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

PUM2_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.075690 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

FUS_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.127169 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

BSN_HUMAN
θ value	0.125558 (rank : 27)	NC score	0.045144 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	1537	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PUM1_MOUSE
θ value	0.125558 (rank : 28)	NC score	0.064826 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6	Gene names	Pum1, Kiaa0099
Domain Architecture
Description	Pumilio homolog 1.

T240L_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.029537 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

EGR1_HUMAN
θ value	0.163984 (rank : 30)	NC score	0.006727 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	788	Shared Neighborhood Hits	9
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

PUM1_HUMAN
θ value	0.163984 (rank : 31)	NC score	0.063816 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q14671, Q5VXY7, Q9HAN1	Gene names	PUM1, KIAA0099, PUMH1
Domain Architecture
Description	Pumilio homolog 1 (Pumilio-1) (HsPUM).

PCLO_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.030226 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	2046	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHC3_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.033103 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

SC24A_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.041242 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	394	Shared Neighborhood Hits	19
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

EWS_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.130929 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	249	Shared Neighborhood Hits	19
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

MUC5B_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.026221 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NFIC_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.033326 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

HNRL1_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.063266 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

SMG7_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.045963 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

HNRL1_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.065573 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

ILF3_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.034690 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

CSPG2_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.012221 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	711	Shared Neighborhood Hits	12
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HXB1_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.013548 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	356	Shared Neighborhood Hits	11
SwissProt Accessions	P14653	Gene names	HOXB1, HOX2I
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2I).

SIP1_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.003356 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

HXB1_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.009116 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	P17919, Q3ZAY6, Q9CYH3	Gene names	Hoxb1, Hox-2.9, Hoxb-1
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2.9).

ZN750_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.035511 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	346	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MDC1_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.037196 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	998	Shared Neighborhood Hits	33
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ATX2L_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.048383 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	443	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BAG3_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.018227 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	513	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

K0460_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.025110 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LEG3_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.028411 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

NDF1_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.017615 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NUP53_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.036328 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

NUPL_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.015386 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

SRBP1_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.025405 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

DDX17_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.018518 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

FOXN3_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.006783 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

LDB3_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.013622 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	497	Shared Neighborhood Hits	12
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PHC1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.029777 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

K1718_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.016475 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MUC2_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.018291 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PAX2_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.011680 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q02962, Q15105, Q15110, Q15837	Gene names	PAX2
Domain Architecture
Description	Paired box protein Pax-2.

PAX2_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.011584 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

TGON2_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.014754 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	1037	Shared Neighborhood Hits	20
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ATX2L_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.046413 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	401	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CECR2_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.017398 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

MAGE1_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.019346 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	1389	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MP2K6_HUMAN
θ value	4.03905 (rank : 68)	NC score	-0.000302 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	830	Shared Neighborhood Hits	4
SwissProt Accessions	P52564	Gene names	MAP2K6, MEK6, MKK6, PRKMK6
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

MP2K6_MOUSE
θ value	4.03905 (rank : 69)	NC score	-0.000286 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	830	Shared Neighborhood Hits	4
SwissProt Accessions	P70236	Gene names	Map2k6, Prkmk6, Sapkk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

K1718_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.014096 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

NOTC1_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.001026 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PMVK_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.021184 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q15126	Gene names	PMVK, PMKI
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

SIGIR_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.009116 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

TRIM8_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.011322 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	650	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.010551 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	674	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

WBP2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.024638 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

WNK1_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.005108 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	1179	Shared Neighborhood Hits	25
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

CG1_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.033190 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	222	Shared Neighborhood Hits	20
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

DDX17_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.013318 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

ERRFI_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.019874 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

NFAC3_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.022037 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NUP62_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.016371 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

RAB6C_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.001804 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0N0, Q9P128	Gene names	RAB6C, WTH3
Domain Architecture
Description	Ras-related protein Rab-6C (Rab6-like protein WTH3).

RFC1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.012029 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

SET1A_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.010115 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	690	Shared Neighborhood Hits	17
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ZIMP7_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.009084 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

DIP2A_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.012227 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2A_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.012332 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DLX4_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.004665 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

IRX6_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.004552 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

MUC13_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.030099 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	447	Shared Neighborhood Hits	18
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NDF1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.010923 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NU214_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.060261 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	657	Shared Neighborhood Hits	30
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

TTC28_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.011999 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ZFYV9_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.004938 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

Hits sorted by NC score

EYA4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_MOUSE
NC score	0.991348 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA2_MOUSE
NC score	0.971330 (rank : 3)	θ value	3.84704e-168 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA2_HUMAN
NC score	0.970280 (rank : 4)	θ value	3.47952e-169 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA1_HUMAN
NC score	0.970248 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA1_MOUSE
NC score	0.969381 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA3_MOUSE
NC score	0.966820 (rank : 7)	θ value	1.01945e-144 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_HUMAN
NC score	0.966193 (rank : 8)	θ value	1.01709e-152 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

FUS_MOUSE
NC score	0.138822 (rank : 9)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

EWS_MOUSE
NC score	0.130986 (rank : 10)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

EWS_HUMAN
NC score	0.130929 (rank : 11)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	249	Shared Neighborhood Hits	19
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

FUS_HUMAN
NC score	0.127169 (rank : 12)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

RPB1_HUMAN
NC score	0.109472 (rank : 13)	θ value	2.44474e-05 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	362	Shared Neighborhood Hits	22
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.109459 (rank : 14)	θ value	2.44474e-05 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	363	Shared Neighborhood Hits	22
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

MCM3A_MOUSE
NC score	0.101839 (rank : 15)	θ value	0.00869519 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

MCM3A_HUMAN
NC score	0.090168 (rank : 16)	θ value	0.00298849 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

TFG_HUMAN
NC score	0.087691 (rank : 17)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

PUM2_HUMAN
NC score	0.079182 (rank : 18)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

PUM2_MOUSE
NC score	0.075690 (rank : 19)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

NU153_HUMAN
NC score	0.074300 (rank : 20)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

HNRL1_MOUSE
NC score	0.065573 (rank : 21)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

PUM1_MOUSE
NC score	0.064826 (rank : 22)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6	Gene names	Pum1, Kiaa0099
Domain Architecture
Description	Pumilio homolog 1.

MAML3_HUMAN
NC score	0.063864 (rank : 23)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

PUM1_HUMAN
NC score	0.063816 (rank : 24)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q14671, Q5VXY7, Q9HAN1	Gene names	PUM1, KIAA0099, PUMH1
Domain Architecture
Description	Pumilio homolog 1 (Pumilio-1) (HsPUM).

HNRL1_HUMAN
NC score	0.063266 (rank : 25)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

ARI1A_HUMAN
NC score	0.062327 (rank : 26)	θ value	0.00869519 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	787	Shared Neighborhood Hits	32
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NU214_HUMAN
NC score	0.060261 (rank : 27)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	657	Shared Neighborhood Hits	30
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SMG7_HUMAN
NC score	0.052149 (rank : 28)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

ATX2L_HUMAN
NC score	0.048383 (rank : 29)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	443	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
NC score	0.046413 (rank : 30)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	401	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

SMG7_MOUSE
NC score	0.045963 (rank : 31)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

BSN_HUMAN
NC score	0.045144 (rank : 32)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	1537	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SC24A_MOUSE
NC score	0.041242 (rank : 33)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	394	Shared Neighborhood Hits	19
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

NFAC3_HUMAN
NC score	0.040275 (rank : 34)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

MDC1_MOUSE
NC score	0.037196 (rank : 35)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	998	Shared Neighborhood Hits	33
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NUP53_MOUSE
NC score	0.036328 (rank : 36)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

ZN750_MOUSE
NC score	0.035511 (rank : 37)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	346	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ILF3_MOUSE
NC score	0.034690 (rank : 38)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

ELN_MOUSE
NC score	0.034507 (rank : 39)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

NFIC_HUMAN
NC score	0.033326 (rank : 40)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

CG1_HUMAN
NC score	0.033190 (rank : 41)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	222	Shared Neighborhood Hits	20
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

PHC3_HUMAN
NC score	0.033103 (rank : 42)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PEPC_HUMAN
NC score	0.032110 (rank : 43)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P20142, Q5T3D7, Q5T3D8	Gene names	PGC
Domain Architecture
Description	Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).

PCLO_HUMAN
NC score	0.030226 (rank : 44)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	2046	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MUC13_MOUSE
NC score	0.030099 (rank : 45)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	447	Shared Neighborhood Hits	18
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PHC1_HUMAN
NC score	0.029777 (rank : 46)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

T240L_MOUSE
NC score	0.029537 (rank : 47)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

LEG3_HUMAN
NC score	0.028411 (rank : 48)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

MUC5B_HUMAN
NC score	0.026221 (rank : 49)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SRBP1_MOUSE
NC score	0.025405 (rank : 50)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

K0460_HUMAN
NC score	0.025110 (rank : 51)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

WBP2_HUMAN
NC score	0.024638 (rank : 52)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

NFAC3_MOUSE
NC score	0.022037 (rank : 53)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PMVK_HUMAN
NC score	0.021184 (rank : 54)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q15126	Gene names	PMVK, PMKI
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

ERRFI_MOUSE
NC score	0.019874 (rank : 55)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

MAGE1_HUMAN
NC score	0.019346 (rank : 56)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	1389	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DDX17_HUMAN
NC score	0.018518 (rank : 57)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

MUC2_HUMAN
NC score	0.018291 (rank : 58)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

BAG3_MOUSE
NC score	0.018227 (rank : 59)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	513	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

NDF1_HUMAN
NC score	0.017615 (rank : 60)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

CECR2_HUMAN
NC score	0.017398 (rank : 61)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

K1718_HUMAN
NC score	0.016475 (rank : 62)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

NUP62_MOUSE
NC score	0.016371 (rank : 63)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

NUPL_HUMAN
NC score	0.015386 (rank : 64)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

TGON2_HUMAN
NC score	0.014754 (rank : 65)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	1037	Shared Neighborhood Hits	20
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

K1718_MOUSE
NC score	0.014096 (rank : 66)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

LDB3_HUMAN
NC score	0.013622 (rank : 67)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	497	Shared Neighborhood Hits	12
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

HXB1_HUMAN
NC score	0.013548 (rank : 68)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	356	Shared Neighborhood Hits	11
SwissProt Accessions	P14653	Gene names	HOXB1, HOX2I
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2I).

DDX17_MOUSE
NC score	0.013318 (rank : 69)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DIP2A_MOUSE
NC score	0.012332 (rank : 70)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2A_HUMAN
NC score	0.012227 (rank : 71)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

CSPG2_MOUSE
NC score	0.012221 (rank : 72)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	711	Shared Neighborhood Hits	12
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

RFC1_HUMAN
NC score	0.012029 (rank : 73)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

TTC28_HUMAN
NC score	0.011999 (rank : 74)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

PAX2_HUMAN
NC score	0.011680 (rank : 75)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q02962, Q15105, Q15110, Q15837	Gene names	PAX2
Domain Architecture
Description	Paired box protein Pax-2.

PAX2_MOUSE
NC score	0.011584 (rank : 76)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

TRIM8_HUMAN
NC score	0.011322 (rank : 77)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	650	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

NDF1_MOUSE
NC score	0.010923 (rank : 78)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

TRIM8_MOUSE
NC score	0.010551 (rank : 79)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	674	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

SET1A_HUMAN
NC score	0.010115 (rank : 80)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	690	Shared Neighborhood Hits	17
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EGR1_MOUSE
NC score	0.009761 (rank : 81)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	816	Shared Neighborhood Hits	19
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

SIGIR_MOUSE
NC score	0.009116 (rank : 82)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

HXB1_MOUSE
NC score	0.009116 (rank : 83)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	P17919, Q3ZAY6, Q9CYH3	Gene names	Hoxb1, Hox-2.9, Hoxb-1
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2.9).

ZIMP7_HUMAN
NC score	0.009084 (rank : 84)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

FOXN3_HUMAN
NC score	0.006783 (rank : 85)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

EGR1_HUMAN
NC score	0.006727 (rank : 86)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	788	Shared Neighborhood Hits	9
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

WNK1_MOUSE
NC score	0.005108 (rank : 87)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	1179	Shared Neighborhood Hits	25
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZFYV9_HUMAN
NC score	0.004938 (rank : 88)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

DLX4_HUMAN
NC score	0.004665 (rank : 89)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

IRX6_HUMAN
NC score	0.004552 (rank : 90)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

SIP1_HUMAN
NC score	0.003356 (rank : 91)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

RAB6C_HUMAN
NC score	0.001804 (rank : 92)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0N0, Q9P128	Gene names	RAB6C, WTH3
Domain Architecture
Description	Ras-related protein Rab-6C (Rab6-like protein WTH3).

NOTC1_MOUSE
NC score	0.001026 (rank : 93)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MP2K6_MOUSE
NC score	-0.000286 (rank : 94)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	830	Shared Neighborhood Hits	4
SwissProt Accessions	P70236	Gene names	Map2k6, Prkmk6, Sapkk3
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).

MP2K6_HUMAN
NC score	-0.000302 (rank : 95)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	830	Shared Neighborhood Hits	4
SwissProt Accessions	P52564	Gene names	MAP2K6, MEK6, MKK6, PRKMK6
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3).