Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : EYA4_MOUSE

For an explanation of this page, click here

EYA4_MOUSE
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EYA1_HUMAN
θ value	0 (rank : 1)	NC score	0.975708 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA1_MOUSE
θ value	0 (rank : 2)	NC score	0.974209 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA4_HUMAN
θ value	0 (rank : 3)	NC score	0.991348 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA2_MOUSE
θ value	2.76339e-158 (rank : 5)	NC score	0.980370 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA2_HUMAN
θ value	2.33935e-157 (rank : 6)	NC score	0.979375 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA3_HUMAN
θ value	2.42085e-154 (rank : 7)	NC score	0.977207 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_MOUSE
θ value	4.13891e-146 (rank : 8)	NC score	0.977410 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

RPB1_HUMAN
θ value	0.00390308 (rank : 9)	NC score	0.090358 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.00390308 (rank : 10)	NC score	0.090345 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

NFAC3_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.041184 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

MAML3_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.059023 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NFIC_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.035614 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

SC24A_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.043167 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	394	Shared Neighborhood Hits	17
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

ATX2L_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.057546 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	443	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

TFG_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.084474 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

HNRL1_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.069923 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

EWS_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.117016 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

HNRL1_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.068453 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

PEPC_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.029996 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P20142, Q5T3D7, Q5T3D8	Gene names	PGC
Domain Architecture
Description	Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).

ARI1A_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.054613 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	787	Shared Neighborhood Hits	28
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATX2L_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.056593 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	401	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

SRBP1_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.030145 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PCLO_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.025801 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	2046	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

FUS_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.122563 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	154	Shared Neighborhood Hits	11
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

LDB3_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.017237 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	497	Shared Neighborhood Hits	12
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

BSN_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.038204 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	1537	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MCM3A_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.058931 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

PHC1_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.029442 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

EWS_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.116616 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

WNK1_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.006072 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	1179	Shared Neighborhood Hits	22
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

LEG3_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.028826 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

MCM3A_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.068516 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

NUP53_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.036476 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

TCOF_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.024060 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CSPG2_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.010331 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DLG5_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.007601 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	1088	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

FUS_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.111984 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

HCFC1_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.020083 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	348	Shared Neighborhood Hits	12
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

NDF1_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.017791 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

CECR2_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.019557 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

HCFC1_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.019482 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ERRFI_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.022467 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

HXB1_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.009095 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	P14653	Gene names	HOXB1, HOX2I
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2I).

K1718_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.016418 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MUC5B_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.018226 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	1020	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TRIM8_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.011559 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	650	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

WBP2_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.026007 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

CG1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.031992 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

DDX17_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.017062 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

K1718_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.014504 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MDC1_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.028371 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	998	Shared Neighborhood Hits	31
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PHC3_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.028876 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

SPEG_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.001038 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	1762	Shared Neighborhood Hits	18
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRIM8_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.011015 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	674	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN750_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.028399 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	346	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

DLX4_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.004027 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

EGR1_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.003141 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	816	Shared Neighborhood Hits	12
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

LDB3_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.010403 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	510	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

NFAC3_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.022429 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PMVK_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.017111 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1G2, Q8R021, Q9D6K3	Gene names	Pmvk
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

RAB6C_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.002161 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0N0, Q9P128	Gene names	RAB6C, WTH3
Domain Architecture
Description	Ras-related protein Rab-6C (Rab6-like protein WTH3).

RFC1_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.012426 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

ROCK1_HUMAN
θ value	6.88961 (rank : 64)	NC score	-0.001916 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	2000	Shared Neighborhood Hits	10
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SPEG_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.000981 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	1959	Shared Neighborhood Hits	23
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ARI1B_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.034307 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	567	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

DDX20_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.003050 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DIP2A_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.012601 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2A_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.012679 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

HGFA_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.000276 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ILF3_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.027552 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

NDF1_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.011010 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	209	Shared Neighborhood Hits	6
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

PMVK_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.024602 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q15126	Gene names	PMVK, PMKI
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

YLPM1_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.017024 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

Hits sorted by NC score

EYA4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_HUMAN
NC score	0.991348 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA2_MOUSE
NC score	0.980370 (rank : 3)	θ value	2.76339e-158 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA2_HUMAN
NC score	0.979375 (rank : 4)	θ value	2.33935e-157 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA3_MOUSE
NC score	0.977410 (rank : 5)	θ value	4.13891e-146 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_HUMAN
NC score	0.977207 (rank : 6)	θ value	2.42085e-154 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA1_HUMAN
NC score	0.975708 (rank : 7)	θ value	0 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA1_MOUSE
NC score	0.974209 (rank : 8)	θ value	0 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

FUS_MOUSE
NC score	0.122563 (rank : 9)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	154	Shared Neighborhood Hits	11
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

EWS_HUMAN
NC score	0.117016 (rank : 10)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
NC score	0.116616 (rank : 11)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

FUS_HUMAN
NC score	0.111984 (rank : 12)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

RPB1_HUMAN
NC score	0.090358 (rank : 13)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.090345 (rank : 14)	θ value	0.00390308 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TFG_HUMAN
NC score	0.084474 (rank : 15)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

HNRL1_MOUSE
NC score	0.069923 (rank : 16)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

MCM3A_MOUSE
NC score	0.068516 (rank : 17)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

HNRL1_HUMAN
NC score	0.068453 (rank : 18)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

MAML3_HUMAN
NC score	0.059023 (rank : 19)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MCM3A_HUMAN
NC score	0.058931 (rank : 20)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

ATX2L_HUMAN
NC score	0.057546 (rank : 21)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	443	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
NC score	0.056593 (rank : 22)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	401	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ARI1A_HUMAN
NC score	0.054613 (rank : 23)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	787	Shared Neighborhood Hits	28
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

SC24A_MOUSE
NC score	0.043167 (rank : 24)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	394	Shared Neighborhood Hits	17
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

NFAC3_HUMAN
NC score	0.041184 (rank : 25)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

BSN_HUMAN
NC score	0.038204 (rank : 26)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	1537	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NUP53_MOUSE
NC score	0.036476 (rank : 27)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

NFIC_HUMAN
NC score	0.035614 (rank : 28)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

ARI1B_HUMAN
NC score	0.034307 (rank : 29)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	567	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CG1_HUMAN
NC score	0.031992 (rank : 30)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

SRBP1_MOUSE
NC score	0.030145 (rank : 31)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PEPC_HUMAN
NC score	0.029996 (rank : 32)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P20142, Q5T3D7, Q5T3D8	Gene names	PGC
Domain Architecture
Description	Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).

PHC1_HUMAN
NC score	0.029442 (rank : 33)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PHC3_HUMAN
NC score	0.028876 (rank : 34)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

LEG3_HUMAN
NC score	0.028826 (rank : 35)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

ZN750_MOUSE
NC score	0.028399 (rank : 36)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	346	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MDC1_MOUSE
NC score	0.028371 (rank : 37)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	998	Shared Neighborhood Hits	31
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ILF3_MOUSE
NC score	0.027552 (rank : 38)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

WBP2_HUMAN
NC score	0.026007 (rank : 39)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

PCLO_HUMAN
NC score	0.025801 (rank : 40)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	2046	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PMVK_HUMAN
NC score	0.024602 (rank : 41)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q15126	Gene names	PMVK, PMKI
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

TCOF_HUMAN
NC score	0.024060 (rank : 42)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ERRFI_MOUSE
NC score	0.022467 (rank : 43)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

NFAC3_MOUSE
NC score	0.022429 (rank : 44)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

HCFC1_MOUSE
NC score	0.020083 (rank : 45)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	348	Shared Neighborhood Hits	12
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

CECR2_HUMAN
NC score	0.019557 (rank : 46)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

HCFC1_HUMAN
NC score	0.019482 (rank : 47)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MUC5B_HUMAN
NC score	0.018226 (rank : 48)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	1020	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NDF1_HUMAN
NC score	0.017791 (rank : 49)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

LDB3_HUMAN
NC score	0.017237 (rank : 50)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	497	Shared Neighborhood Hits	12
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PMVK_MOUSE
NC score	0.017111 (rank : 51)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1G2, Q8R021, Q9D6K3	Gene names	Pmvk
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

DDX17_HUMAN
NC score	0.017062 (rank : 52)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

YLPM1_MOUSE
NC score	0.017024 (rank : 53)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

K1718_HUMAN
NC score	0.016418 (rank : 54)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

K1718_MOUSE
NC score	0.014504 (rank : 55)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

DIP2A_MOUSE
NC score	0.012679 (rank : 56)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2A_HUMAN
NC score	0.012601 (rank : 57)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

RFC1_HUMAN
NC score	0.012426 (rank : 58)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

TRIM8_HUMAN
NC score	0.011559 (rank : 59)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	650	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
NC score	0.011015 (rank : 60)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	674	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

NDF1_MOUSE
NC score	0.011010 (rank : 61)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	209	Shared Neighborhood Hits	6
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

LDB3_MOUSE
NC score	0.010403 (rank : 62)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	510	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CSPG2_MOUSE
NC score	0.010331 (rank : 63)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HXB1_HUMAN
NC score	0.009095 (rank : 64)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	P14653	Gene names	HOXB1, HOX2I
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2I).

DLG5_HUMAN
NC score	0.007601 (rank : 65)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	1088	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

WNK1_MOUSE
NC score	0.006072 (rank : 66)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	1179	Shared Neighborhood Hits	22
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

DLX4_HUMAN
NC score	0.004027 (rank : 67)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

EGR1_MOUSE
NC score	0.003141 (rank : 68)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	816	Shared Neighborhood Hits	12
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

DDX20_MOUSE
NC score	0.003050 (rank : 69)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

RAB6C_HUMAN
NC score	0.002161 (rank : 70)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0N0, Q9P128	Gene names	RAB6C, WTH3
Domain Architecture
Description	Ras-related protein Rab-6C (Rab6-like protein WTH3).

SPEG_HUMAN
NC score	0.001038 (rank : 71)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	1762	Shared Neighborhood Hits	18
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
NC score	0.000981 (rank : 72)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	1959	Shared Neighborhood Hits	23
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

HGFA_MOUSE
NC score	0.000276 (rank : 73)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ROCK1_HUMAN
NC score	-0.001916 (rank : 74)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	2000	Shared Neighborhood Hits	10
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).