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Network neighborhood for query Sequence : SMG7_HUMAN

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SMG7_HUMAN
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMG7_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMG7_MOUSE
θ value	0 (rank : 2)	NC score	0.984958 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	113	Shared Neighborhood Hits	68
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

EST1A_HUMAN
θ value	4.15078e-21 (rank : 3)	NC score	0.532098 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

EST1A_MOUSE
θ value	7.0802e-21 (rank : 4)	NC score	0.521121 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

SMG5_HUMAN
θ value	1.29331e-14 (rank : 5)	NC score	0.467036 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SMG5_MOUSE
θ value	1.29331e-14 (rank : 6)	NC score	0.488559 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

MAGE1_HUMAN
θ value	0.00390308 (rank : 7)	NC score	0.055087 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	1389	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ZIM10_MOUSE
θ value	0.00509761 (rank : 8)	NC score	0.096832 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	430	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MLL3_HUMAN
θ value	0.0193708 (rank : 9)	NC score	0.073533 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	1644	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EYA4_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.052149 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

SRRM2_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.081292 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CCNK_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.079212 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

EP400_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.053173 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TPO_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.096616 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

ZIM10_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.077764 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

AAK1_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.024146 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

R3HD2_MOUSE
θ value	0.163984 (rank : 17)	NC score	0.079445 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	397	Shared Neighborhood Hits	39
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

GA2L2_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.046108 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	395	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GP152_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.041631 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	636	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

SCAM2_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.041116 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O15127, Q9BQE8	Gene names	SCAMP2
Domain Architecture
Description	Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2).

CDC16_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.092561 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q13042, Q96AE6, Q9Y564	Gene names	CDC16
Domain Architecture
Description	Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

CDC16_MOUSE
θ value	0.47712 (rank : 22)	NC score	0.091981 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R349, Q9CYX9	Gene names	Cdc16
Domain Architecture
Description	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

DAZ2_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.062977 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q13117, Q96P41, Q9NR91	Gene names	DAZ2
Domain Architecture
Description	Deleted in azoospermia protein 2.

PGBM_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.012541 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	1113	Shared Neighborhood Hits	14
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

UBP8_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.024790 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	362	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

CSF1_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.047791 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	258	Shared Neighborhood Hits	19
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

PCLO_MOUSE
θ value	0.62314 (rank : 27)	NC score	0.044695 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	2275	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TAU_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.048134 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	502	Shared Neighborhood Hits	28
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CIZ1_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.089954 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

DAZ3_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.059737 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR90	Gene names	DAZ3
Domain Architecture
Description	Deleted in azoospermia protein 3.

MACF1_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.012833 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	1341	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MDC1_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.056790 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	1446	Shared Neighborhood Hits	52
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NEK4_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.006695 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	883	Shared Neighborhood Hits	6
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

BSN_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.062058 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	2057	Shared Neighborhood Hits	70
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD45_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.029724 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

GON4L_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.047732 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LARP4_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.051947 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LMBL3_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.032821 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	212	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

MAML3_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.056042 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

OGT1_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.046234 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

PCQAP_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.067345 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	549	Shared Neighborhood Hits	36
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

BRD4_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.041753 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DAZ1_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.053571 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	192	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQZ3, Q9NQZ4	Gene names	DAZ1, DAZ
Domain Architecture
Description	Deleted in azoospermia protein 1.

DAZ4_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.053608 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	192	Shared Neighborhood Hits	9
SwissProt Accessions	Q86SG3, Q9NR88, Q9NR89	Gene names	DAZ4
Domain Architecture
Description	Deleted in azoospermia protein 4.

FOXM1_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.022574 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

LIPS_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.046497 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	314	Shared Neighborhood Hits	29
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

NRX2A_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.031356 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	614	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.041520 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	481	Shared Neighborhood Hits	22
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PORIM_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.065052 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

NCOA6_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.062507 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	1202	Shared Neighborhood Hits	60
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

AKAP2_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.023802 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	507	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MTMR7_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.017108 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

RERE_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.050772 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	785	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SC24C_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.041677 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	662	Shared Neighborhood Hits	35
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

KI67_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.041674 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

NCOR2_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.038870 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	870	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

STAM2_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.012724 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ZEP2_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.008790 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	937	Shared Neighborhood Hits	19
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ARI1A_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.059073 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	787	Shared Neighborhood Hits	46
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ASTL_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.016368 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATX2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.044494 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	445	Shared Neighborhood Hits	43
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BAT2_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.035483 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	947	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EMSY_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.054682 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	296	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

GOGB1_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.011691 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	2297	Shared Neighborhood Hits	31
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GTSE1_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.031237 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	245	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

MDC1_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.048478 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	998	Shared Neighborhood Hits	48
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NFM_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.010089 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	1328	Shared Neighborhood Hits	32
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PAIP1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.044845 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

RASF1_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.026610 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

SCUB3_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.007821 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	442	Shared Neighborhood Hits	4
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SRGP1_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.010214 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	390	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TREF1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.022447 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	651	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

CCNB3_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.012503 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

FOXJ3_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.010095 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

INVS_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.008586 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	609	Shared Neighborhood Hits	17
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

KLF3_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.001411 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	715	Shared Neighborhood Hits	11
SwissProt Accessions	Q60980	Gene names	Klf3, Bklf
Domain Architecture
Description	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2).

LAP2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.006544 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	499	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MNAB_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.014976 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MYST4_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.017350 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	671	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NACAM_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.043206 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	1866	Shared Neighborhood Hits	63
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PO6F2_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.025500 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	618	Shared Neighborhood Hits	29
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SCUB3_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.007499 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SFR15_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.046401 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

AMELX_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.057204 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

ARI1B_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.043397 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	567	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CBPB2_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.007426 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

EDA_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.025385 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

HCFC1_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.019334 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	348	Shared Neighborhood Hits	17
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

IFT88_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.019305 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

LATS1_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.005646 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	1057	Shared Neighborhood Hits	26
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

MLL3_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.044021 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	1399	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ODO2_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.016533 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

P3C2A_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.008273 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PCNT_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.013202 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	1207	Shared Neighborhood Hits	18
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RERE_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.046452 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	779	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPR1B_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.025537 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

TBX21_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.010401 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

ZN509_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.000763 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	990	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

APLP1_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.016433 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	130	Shared Neighborhood Hits	9
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

ATX2L_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.035976 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	443	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CAF1A_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.021078 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	736	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DNMBP_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.009748 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EGR1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.002443 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	816	Shared Neighborhood Hits	20
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

FHL1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.004607 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	436	Shared Neighborhood Hits	5
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

ITSN1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.009446 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	1757	Shared Neighborhood Hits	33
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

K0831_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.011901 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

K1718_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.015202 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

LATS1_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.005580 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	1027	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MAP4_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.032488 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	428	Shared Neighborhood Hits	26
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MINT_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.024555 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	1291	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL4_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.035816 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	722	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NFAT5_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.029655 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NGEF_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.014481 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PDZD2_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.018381 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	772	Shared Neighborhood Hits	27
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PTN4_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.002734 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

ZEP1_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.009484 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	1036	Shared Neighborhood Hits	32
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZN710_HUMAN
θ value	8.99809 (rank : 117)	NC score	-0.000006 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	796	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

CA026_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.055489 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

NCOA6_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.052164 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	1076	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

Hits sorted by NC score

SMG7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SMG7_MOUSE
NC score	0.984958 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	113	Shared Neighborhood Hits	68
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

EST1A_HUMAN
NC score	0.532098 (rank : 3)	θ value	4.15078e-21 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

EST1A_MOUSE
NC score	0.521121 (rank : 4)	θ value	7.0802e-21 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

SMG5_MOUSE
NC score	0.488559 (rank : 5)	θ value	1.29331e-14 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

SMG5_HUMAN
NC score	0.467036 (rank : 6)	θ value	1.29331e-14 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

ZIM10_MOUSE
NC score	0.096832 (rank : 7)	θ value	0.00509761 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	430	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

TPO_MOUSE
NC score	0.096616 (rank : 8)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

CDC16_HUMAN
NC score	0.092561 (rank : 9)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q13042, Q96AE6, Q9Y564	Gene names	CDC16
Domain Architecture
Description	Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

CDC16_MOUSE
NC score	0.091981 (rank : 10)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R349, Q9CYX9	Gene names	Cdc16
Domain Architecture
Description	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

CIZ1_HUMAN
NC score	0.089954 (rank : 11)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SRRM2_MOUSE
NC score	0.081292 (rank : 12)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

R3HD2_MOUSE
NC score	0.079445 (rank : 13)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	397	Shared Neighborhood Hits	39
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CCNK_HUMAN
NC score	0.079212 (rank : 14)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

ZIM10_HUMAN
NC score	0.077764 (rank : 15)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MLL3_HUMAN
NC score	0.073533 (rank : 16)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	1644	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCQAP_HUMAN
NC score	0.067345 (rank : 17)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	549	Shared Neighborhood Hits	36
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PORIM_MOUSE
NC score	0.065052 (rank : 18)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q91Z22, Q3T9F6, Q3TLL2, Q3U1R6, Q8CEX4	Gene names	Tmem123
Domain Architecture	No domain graphic available
Description	Porimin precursor (Transmembrane protein 123).

DAZ2_HUMAN
NC score	0.062977 (rank : 19)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q13117, Q96P41, Q9NR91	Gene names	DAZ2
Domain Architecture
Description	Deleted in azoospermia protein 2.

NCOA6_HUMAN
NC score	0.062507 (rank : 20)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	1202	Shared Neighborhood Hits	60
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BSN_MOUSE
NC score	0.062058 (rank : 21)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	2057	Shared Neighborhood Hits	70
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DAZ3_HUMAN
NC score	0.059737 (rank : 22)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR90	Gene names	DAZ3
Domain Architecture
Description	Deleted in azoospermia protein 3.

ARI1A_HUMAN
NC score	0.059073 (rank : 23)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	787	Shared Neighborhood Hits	46
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

AMELX_HUMAN
NC score	0.057204 (rank : 24)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

MDC1_HUMAN
NC score	0.056790 (rank : 25)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	1446	Shared Neighborhood Hits	52
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MAML3_HUMAN
NC score	0.056042 (rank : 26)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

CA026_MOUSE
NC score	0.055489 (rank : 27)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

MAGE1_HUMAN
NC score	0.055087 (rank : 28)	θ value	0.00390308 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	1389	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

EMSY_HUMAN
NC score	0.054682 (rank : 29)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	296	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

DAZ4_HUMAN
NC score	0.053608 (rank : 30)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	192	Shared Neighborhood Hits	9
SwissProt Accessions	Q86SG3, Q9NR88, Q9NR89	Gene names	DAZ4
Domain Architecture
Description	Deleted in azoospermia protein 4.

DAZ1_HUMAN
NC score	0.053571 (rank : 31)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	192	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQZ3, Q9NQZ4	Gene names	DAZ1, DAZ
Domain Architecture
Description	Deleted in azoospermia protein 1.

EP400_MOUSE
NC score	0.053173 (rank : 32)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

NCOA6_MOUSE
NC score	0.052164 (rank : 33)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	1076	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

EYA4_HUMAN
NC score	0.052149 (rank : 34)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

LARP4_MOUSE
NC score	0.051947 (rank : 35)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

RERE_MOUSE
NC score	0.050772 (rank : 36)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	785	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MDC1_MOUSE
NC score	0.048478 (rank : 37)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	998	Shared Neighborhood Hits	48
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

TAU_MOUSE
NC score	0.048134 (rank : 38)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	502	Shared Neighborhood Hits	28
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CSF1_HUMAN
NC score	0.047791 (rank : 39)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	258	Shared Neighborhood Hits	19
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GON4L_MOUSE
NC score	0.047732 (rank : 40)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LIPS_HUMAN
NC score	0.046497 (rank : 41)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	314	Shared Neighborhood Hits	29
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

RERE_HUMAN
NC score	0.046452 (rank : 42)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	779	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SFR15_HUMAN
NC score	0.046401 (rank : 43)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

OGT1_HUMAN
NC score	0.046234 (rank : 44)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

GA2L2_MOUSE
NC score	0.046108 (rank : 45)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	395	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PAIP1_HUMAN
NC score	0.044845 (rank : 46)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

PCLO_MOUSE
NC score	0.044695 (rank : 47)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	2275	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ATX2_MOUSE
NC score	0.044494 (rank : 48)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	445	Shared Neighborhood Hits	43
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MLL3_MOUSE
NC score	0.044021 (rank : 49)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	1399	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ARI1B_HUMAN
NC score	0.043397 (rank : 50)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	567	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

NACAM_MOUSE
NC score	0.043206 (rank : 51)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	1866	Shared Neighborhood Hits	63
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BRD4_HUMAN
NC score	0.041753 (rank : 52)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

SC24C_HUMAN
NC score	0.041677 (rank : 53)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	662	Shared Neighborhood Hits	35
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

KI67_HUMAN
NC score	0.041674 (rank : 54)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

GP152_HUMAN
NC score	0.041631 (rank : 55)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	636	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

NRX2B_HUMAN
NC score	0.041520 (rank : 56)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	481	Shared Neighborhood Hits	22
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SCAM2_HUMAN
NC score	0.041116 (rank : 57)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O15127, Q9BQE8	Gene names	SCAMP2
Domain Architecture
Description	Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2).

NCOR2_HUMAN
NC score	0.038870 (rank : 58)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	870	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ATX2L_HUMAN
NC score	0.035976 (rank : 59)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	443	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

MLL4_HUMAN
NC score	0.035816 (rank : 60)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	722	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

BAT2_MOUSE
NC score	0.035483 (rank : 61)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	947	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

LMBL3_MOUSE
NC score	0.032821 (rank : 62)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	212	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

MAP4_HUMAN
NC score	0.032488 (rank : 63)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	428	Shared Neighborhood Hits	26
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NRX2A_HUMAN
NC score	0.031356 (rank : 64)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	614	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

GTSE1_MOUSE
NC score	0.031237 (rank : 65)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	245	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

CCD45_MOUSE
NC score	0.029724 (rank : 66)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

NFAT5_HUMAN
NC score	0.029655 (rank : 67)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

RASF1_HUMAN
NC score	0.026610 (rank : 68)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

SPR1B_HUMAN
NC score	0.025537 (rank : 69)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

PO6F2_HUMAN
NC score	0.025500 (rank : 70)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	618	Shared Neighborhood Hits	29
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

EDA_MOUSE
NC score	0.025385 (rank : 71)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

UBP8_MOUSE
NC score	0.024790 (rank : 72)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	362	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

MINT_HUMAN
NC score	0.024555 (rank : 73)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	1291	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

AAK1_MOUSE
NC score	0.024146 (rank : 74)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AKAP2_HUMAN
NC score	0.023802 (rank : 75)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	507	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

FOXM1_HUMAN
NC score	0.022574 (rank : 76)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

TREF1_HUMAN
NC score	0.022447 (rank : 77)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	651	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

CAF1A_MOUSE
NC score	0.021078 (rank : 78)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	736	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

HCFC1_MOUSE
NC score	0.019334 (rank : 79)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	348	Shared Neighborhood Hits	17
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

IFT88_MOUSE
NC score	0.019305 (rank : 80)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

PDZD2_HUMAN
NC score	0.018381 (rank : 81)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	772	Shared Neighborhood Hits	27
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

MYST4_HUMAN
NC score	0.017350 (rank : 82)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	671	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MTMR7_MOUSE
NC score	0.017108 (rank : 83)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

ODO2_MOUSE
NC score	0.016533 (rank : 84)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

APLP1_MOUSE
NC score	0.016433 (rank : 85)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	130	Shared Neighborhood Hits	9
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

ASTL_MOUSE
NC score	0.016368 (rank : 86)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

K1718_HUMAN
NC score	0.015202 (rank : 87)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MNAB_HUMAN
NC score	0.014976 (rank : 88)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

NGEF_MOUSE
NC score	0.014481 (rank : 89)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PCNT_MOUSE
NC score	0.013202 (rank : 90)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	1207	Shared Neighborhood Hits	18
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

MACF1_HUMAN
NC score	0.012833 (rank : 91)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	1341	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

STAM2_MOUSE
NC score	0.012724 (rank : 92)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

PGBM_HUMAN
NC score	0.012541 (rank : 93)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	1113	Shared Neighborhood Hits	14
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CCNB3_HUMAN
NC score	0.012503 (rank : 94)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

K0831_HUMAN
NC score	0.011901 (rank : 95)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

GOGB1_HUMAN
NC score	0.011691 (rank : 96)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	2297	Shared Neighborhood Hits	31
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TBX21_HUMAN
NC score	0.010401 (rank : 97)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

SRGP1_HUMAN
NC score	0.010214 (rank : 98)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	390	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FOXJ3_MOUSE
NC score	0.010095 (rank : 99)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

NFM_HUMAN
NC score	0.010089 (rank : 100)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	1328	Shared Neighborhood Hits	32
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

DNMBP_MOUSE
NC score	0.009748 (rank : 101)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ZEP1_HUMAN
NC score	0.009484 (rank : 102)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	1036	Shared Neighborhood Hits	32
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ITSN1_HUMAN
NC score	0.009446 (rank : 103)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	1757	Shared Neighborhood Hits	33
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ZEP2_HUMAN
NC score	0.008790 (rank : 104)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	937	Shared Neighborhood Hits	19
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

INVS_MOUSE
NC score	0.008586 (rank : 105)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	609	Shared Neighborhood Hits	17
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

P3C2A_HUMAN
NC score	0.008273 (rank : 106)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

SCUB3_MOUSE
NC score	0.007821 (rank : 107)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	442	Shared Neighborhood Hits	4
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.007499 (rank : 108)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CBPB2_MOUSE
NC score	0.007426 (rank : 109)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

NEK4_HUMAN
NC score	0.006695 (rank : 110)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	883	Shared Neighborhood Hits	6
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

LAP2_HUMAN
NC score	0.006544 (rank : 111)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	499	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LATS1_HUMAN
NC score	0.005646 (rank : 112)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	1057	Shared Neighborhood Hits	26
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

LATS1_MOUSE
NC score	0.005580 (rank : 113)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	1027	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

FHL1_HUMAN
NC score	0.004607 (rank : 114)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	436	Shared Neighborhood Hits	5
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

PTN4_HUMAN
NC score	0.002734 (rank : 115)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

EGR1_MOUSE
NC score	0.002443 (rank : 116)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	816	Shared Neighborhood Hits	20
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

KLF3_MOUSE
NC score	0.001411 (rank : 117)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	715	Shared Neighborhood Hits	11
SwissProt Accessions	Q60980	Gene names	Klf3, Bklf
Domain Architecture
Description	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2).

ZN509_MOUSE
NC score	0.000763 (rank : 118)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	990	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN710_HUMAN
NC score	-0.000006 (rank : 119)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	796	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.