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Network neighborhood for query Sequence : PTN4_HUMAN

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PTN4_HUMAN
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTN3_HUMAN
θ value	0 (rank : 1)	NC score	0.990853 (rank : 2)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	216
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	303	Target Neighborhood Hits	303	Shared Neighborhood Hits	303
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L1_HUMAN
θ value	8.77142e-88 (rank : 3)	NC score	0.673892 (rank : 59)
Query Neighborhood Hits	303	Target Neighborhood Hits	180	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
θ value	4.35321e-87 (rank : 4)	NC score	0.677364 (rank : 53)
Query Neighborhood Hits	303	Target Neighborhood Hits	106	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L2_HUMAN
θ value	2.02215e-84 (rank : 5)	NC score	0.667593 (rank : 63)
Query Neighborhood Hits	303	Target Neighborhood Hits	287	Shared Neighborhood Hits	55
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_HUMAN
θ value	7.68416e-84 (rank : 6)	NC score	0.678999 (rank : 48)
Query Neighborhood Hits	303	Target Neighborhood Hits	113	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	2.23575e-83 (rank : 7)	NC score	0.669073 (rank : 62)
Query Neighborhood Hits	303	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

41_HUMAN
θ value	2.47191e-82 (rank : 8)	NC score	0.676997 (rank : 55)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L2_MOUSE
θ value	4.66183e-81 (rank : 9)	NC score	0.650264 (rank : 70)
Query Neighborhood Hits	303	Target Neighborhood Hits	459	Shared Neighborhood Hits	59
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

41_MOUSE
θ value	1.35638e-80 (rank : 10)	NC score	0.675060 (rank : 58)
Query Neighborhood Hits	303	Target Neighborhood Hits	184	Shared Neighborhood Hits	55
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

FARP2_HUMAN
θ value	3.45727e-76 (rank : 11)	NC score	0.549199 (rank : 82)
Query Neighborhood Hits	303	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	4.51533e-76 (rank : 12)	NC score	0.543994 (rank : 83)
Query Neighborhood Hits	303	Target Neighborhood Hits	209	Shared Neighborhood Hits	50
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

E41LA_HUMAN
θ value	2.47765e-74 (rank : 13)	NC score	0.680963 (rank : 45)
Query Neighborhood Hits	303	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L5_HUMAN
θ value	6.7473e-72 (rank : 14)	NC score	0.681309 (rank : 44)
Query Neighborhood Hits	303	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LA_MOUSE
θ value	1.27248e-70 (rank : 15)	NC score	0.680684 (rank : 46)
Query Neighborhood Hits	303	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_MOUSE
θ value	1.66191e-70 (rank : 16)	NC score	0.682511 (rank : 43)
Query Neighborhood Hits	303	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FARP1_HUMAN
θ value	8.24801e-70 (rank : 17)	NC score	0.564268 (rank : 76)
Query Neighborhood Hits	303	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

E41LB_HUMAN
θ value	1.83746e-69 (rank : 18)	NC score	0.677141 (rank : 54)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FRMD5_MOUSE
θ value	2.48917e-58 (rank : 19)	NC score	0.678073 (rank : 52)
Query Neighborhood Hits	303	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
θ value	4.24587e-58 (rank : 20)	NC score	0.676529 (rank : 57)
Query Neighborhood Hits	303	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

PTN14_HUMAN
θ value	4.54686e-52 (rank : 21)	NC score	0.916968 (rank : 6)
Query Neighborhood Hits	303	Target Neighborhood Hits	163	Shared Neighborhood Hits	113
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	6.56568e-51 (rank : 22)	NC score	0.918168 (rank : 5)
Query Neighborhood Hits	303	Target Neighborhood Hits	142	Shared Neighborhood Hits	108
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN13_HUMAN
θ value	4.40402e-47 (rank : 23)	NC score	0.862901 (rank : 8)
Query Neighborhood Hits	303	Target Neighborhood Hits	471	Shared Neighborhood Hits	226
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTPRK_HUMAN
θ value	5.7518e-47 (rank : 24)	NC score	0.678430 (rank : 51)
Query Neighborhood Hits	303	Target Neighborhood Hits	228	Shared Neighborhood Hits	69
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	5.7518e-47 (rank : 25)	NC score	0.676768 (rank : 56)
Query Neighborhood Hits	303	Target Neighborhood Hits	223	Shared Neighborhood Hits	67
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN13_MOUSE
θ value	9.81109e-47 (rank : 26)	NC score	0.871849 (rank : 7)
Query Neighborhood Hits	303	Target Neighborhood Hits	426	Shared Neighborhood Hits	228
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTPRS_HUMAN
θ value	1.28137e-46 (rank : 27)	NC score	0.527996 (rank : 84)
Query Neighborhood Hits	303	Target Neighborhood Hits	472	Shared Neighborhood Hits	75
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRJ_HUMAN
θ value	3.72821e-46 (rank : 28)	NC score	0.706506 (rank : 39)
Query Neighborhood Hits	303	Target Neighborhood Hits	207	Shared Neighborhood Hits	78
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN6_HUMAN
θ value	4.86918e-46 (rank : 29)	NC score	0.697676 (rank : 41)
Query Neighborhood Hits	303	Target Neighborhood Hits	234	Shared Neighborhood Hits	71
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRD_HUMAN
θ value	6.35935e-46 (rank : 30)	NC score	0.518143 (rank : 87)
Query Neighborhood Hits	303	Target Neighborhood Hits	485	Shared Neighborhood Hits	77
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTN6_MOUSE
θ value	8.30557e-46 (rank : 31)	NC score	0.695589 (rank : 42)
Query Neighborhood Hits	303	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRJ_MOUSE
θ value	8.30557e-46 (rank : 32)	NC score	0.709611 (rank : 38)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	76
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN21_MOUSE
θ value	5.38352e-45 (rank : 33)	NC score	0.922410 (rank : 4)
Query Neighborhood Hits	303	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	7.03111e-45 (rank : 34)	NC score	0.922494 (rank : 3)
Query Neighborhood Hits	303	Target Neighborhood Hits	143	Shared Neighborhood Hits	108
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTPRF_HUMAN
θ value	9.18288e-45 (rank : 35)	NC score	0.515355 (rank : 88)
Query Neighborhood Hits	303	Target Neighborhood Hits	489	Shared Neighborhood Hits	75
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTN2_MOUSE
θ value	1.56636e-44 (rank : 36)	NC score	0.742719 (rank : 10)
Query Neighborhood Hits	303	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN9_HUMAN
θ value	1.56636e-44 (rank : 37)	NC score	0.728057 (rank : 23)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	2.67181e-44 (rank : 38)	NC score	0.728261 (rank : 22)
Query Neighborhood Hits	303	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN18_HUMAN
θ value	3.48949e-44 (rank : 39)	NC score	0.742601 (rank : 11)
Query Neighborhood Hits	303	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN2_HUMAN
θ value	4.55743e-44 (rank : 40)	NC score	0.742438 (rank : 13)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	65
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN1_HUMAN
θ value	7.77379e-44 (rank : 41)	NC score	0.742444 (rank : 12)
Query Neighborhood Hits	303	Target Neighborhood Hits	84	Shared Neighborhood Hits	66
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTPRT_HUMAN
θ value	1.01529e-43 (rank : 42)	NC score	0.672954 (rank : 61)
Query Neighborhood Hits	303	Target Neighborhood Hits	217	Shared Neighborhood Hits	68
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	1.01529e-43 (rank : 43)	NC score	0.672955 (rank : 60)
Query Neighborhood Hits	303	Target Neighborhood Hits	219	Shared Neighborhood Hits	68
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRB_HUMAN
θ value	1.73182e-43 (rank : 44)	NC score	0.680174 (rank : 47)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	76
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN1_MOUSE
θ value	2.26182e-43 (rank : 45)	NC score	0.742747 (rank : 9)
Query Neighborhood Hits	303	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTPRM_MOUSE
θ value	2.50074e-42 (rank : 46)	NC score	0.662578 (rank : 65)
Query Neighborhood Hits	303	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
θ value	3.26607e-42 (rank : 47)	NC score	0.661001 (rank : 66)
Query Neighborhood Hits	303	Target Neighborhood Hits	244	Shared Neighborhood Hits	69
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRA_MOUSE
θ value	7.27602e-42 (rank : 48)	NC score	0.723381 (rank : 33)
Query Neighborhood Hits	303	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRA_HUMAN
θ value	9.50281e-42 (rank : 49)	NC score	0.723811 (rank : 31)
Query Neighborhood Hits	303	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTN11_HUMAN
θ value	1.62093e-41 (rank : 50)	NC score	0.678794 (rank : 50)
Query Neighborhood Hits	303	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	1.62093e-41 (rank : 51)	NC score	0.678846 (rank : 49)
Query Neighborhood Hits	303	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	1.62093e-41 (rank : 52)	NC score	0.734518 (rank : 17)
Query Neighborhood Hits	303	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	1.62093e-41 (rank : 53)	NC score	0.734066 (rank : 19)
Query Neighborhood Hits	303	Target Neighborhood Hits	123	Shared Neighborhood Hits	71
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRE_HUMAN
θ value	2.11701e-41 (rank : 54)	NC score	0.724248 (rank : 29)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	71
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN22_HUMAN
θ value	2.76489e-41 (rank : 55)	NC score	0.734283 (rank : 18)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRE_MOUSE
θ value	6.15952e-41 (rank : 56)	NC score	0.723862 (rank : 30)
Query Neighborhood Hits	303	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRO_HUMAN
θ value	6.15952e-41 (rank : 57)	NC score	0.729083 (rank : 20)
Query Neighborhood Hits	303	Target Neighborhood Hits	139	Shared Neighborhood Hits	74
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRV_MOUSE
θ value	6.15952e-41 (rank : 58)	NC score	0.699577 (rank : 40)
Query Neighborhood Hits	303	Target Neighborhood Hits	179	Shared Neighborhood Hits	71
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRD_MOUSE
θ value	1.79215e-40 (rank : 59)	NC score	0.509225 (rank : 91)
Query Neighborhood Hits	303	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPR2_MOUSE
θ value	2.34062e-40 (rank : 60)	NC score	0.727143 (rank : 25)
Query Neighborhood Hits	303	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRG_HUMAN
θ value	2.34062e-40 (rank : 61)	NC score	0.653356 (rank : 68)
Query Neighborhood Hits	303	Target Neighborhood Hits	231	Shared Neighborhood Hits	68
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRN_MOUSE
θ value	2.34062e-40 (rank : 62)	NC score	0.720302 (rank : 36)
Query Neighborhood Hits	303	Target Neighborhood Hits	240	Shared Neighborhood Hits	76
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN18_MOUSE
θ value	5.21438e-40 (rank : 63)	NC score	0.740833 (rank : 14)
Query Neighborhood Hits	303	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTPRZ_HUMAN
θ value	6.81017e-40 (rank : 64)	NC score	0.654240 (rank : 67)
Query Neighborhood Hits	303	Target Neighborhood Hits	255	Shared Neighborhood Hits	74
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPR2_HUMAN
θ value	1.16164e-39 (rank : 65)	NC score	0.728739 (rank : 21)
Query Neighborhood Hits	303	Target Neighborhood Hits	103	Shared Neighborhood Hits	69
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRG_MOUSE
θ value	1.16164e-39 (rank : 66)	NC score	0.651325 (rank : 69)
Query Neighborhood Hits	303	Target Neighborhood Hits	260	Shared Neighborhood Hits	72
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRN_HUMAN
θ value	1.16164e-39 (rank : 67)	NC score	0.723236 (rank : 34)
Query Neighborhood Hits	303	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

CD45_HUMAN
θ value	4.41421e-39 (rank : 68)	NC score	0.718991 (rank : 37)
Query Neighborhood Hits	303	Target Neighborhood Hits	243	Shared Neighborhood Hits	73
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRU_HUMAN
θ value	1.28434e-38 (rank : 69)	NC score	0.666177 (rank : 64)
Query Neighborhood Hits	303	Target Neighborhood Hits	237	Shared Neighborhood Hits	70
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTN7_MOUSE
θ value	2.86122e-38 (rank : 70)	NC score	0.736822 (rank : 15)
Query Neighborhood Hits	303	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN22_MOUSE
θ value	3.73686e-38 (rank : 71)	NC score	0.727969 (rank : 24)
Query Neighborhood Hits	303	Target Neighborhood Hits	179	Shared Neighborhood Hits	71
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

CD45_MOUSE
θ value	4.88048e-38 (rank : 72)	NC score	0.724735 (rank : 28)
Query Neighborhood Hits	303	Target Neighborhood Hits	178	Shared Neighborhood Hits	71
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTN7_HUMAN
θ value	3.16345e-37 (rank : 73)	NC score	0.736017 (rank : 16)
Query Neighborhood Hits	303	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

RADI_HUMAN
θ value	3.61944e-33 (rank : 74)	NC score	0.514738 (rank : 89)
Query Neighborhood Hits	303	Target Neighborhood Hits	741	Shared Neighborhood Hits	54
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	3.61944e-33 (rank : 75)	NC score	0.511816 (rank : 90)
Query Neighborhood Hits	303	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

EZRI_MOUSE
θ value	1.37539e-32 (rank : 76)	NC score	0.524148 (rank : 86)
Query Neighborhood Hits	303	Target Neighborhood Hits	693	Shared Neighborhood Hits	52
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTN23_HUMAN
θ value	1.37539e-32 (rank : 77)	NC score	0.637938 (rank : 71)
Query Neighborhood Hits	303	Target Neighborhood Hits	646	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

MOES_MOUSE
θ value	1.79631e-32 (rank : 78)	NC score	0.476942 (rank : 96)
Query Neighborhood Hits	303	Target Neighborhood Hits	923	Shared Neighborhood Hits	57
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MERL_HUMAN
θ value	2.34606e-32 (rank : 79)	NC score	0.556670 (rank : 81)
Query Neighborhood Hits	303	Target Neighborhood Hits	532	Shared Neighborhood Hits	57
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MOES_HUMAN
θ value	2.34606e-32 (rank : 80)	NC score	0.481874 (rank : 94)
Query Neighborhood Hits	303	Target Neighborhood Hits	892	Shared Neighborhood Hits	53
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

EZRI_HUMAN
θ value	3.06405e-32 (rank : 81)	NC score	0.527427 (rank : 85)
Query Neighborhood Hits	303	Target Neighborhood Hits	663	Shared Neighborhood Hits	51
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MERL_MOUSE
θ value	3.06405e-32 (rank : 82)	NC score	0.557131 (rank : 80)
Query Neighborhood Hits	303	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTPRR_HUMAN
θ value	4.00176e-32 (rank : 83)	NC score	0.723433 (rank : 32)
Query Neighborhood Hits	303	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	4.00176e-32 (rank : 84)	NC score	0.723160 (rank : 35)
Query Neighborhood Hits	303	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTN23_MOUSE
θ value	1.16434e-31 (rank : 85)	NC score	0.637869 (rank : 72)
Query Neighborhood Hits	303	Target Neighborhood Hits	726	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MYLIP_MOUSE
θ value	4.42448e-31 (rank : 86)	NC score	0.615641 (rank : 73)
Query Neighborhood Hits	303	Target Neighborhood Hits	139	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
θ value	2.19584e-30 (rank : 87)	NC score	0.603077 (rank : 74)
Query Neighborhood Hits	303	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN5_HUMAN
θ value	2.05525e-28 (rank : 88)	NC score	0.725881 (rank : 27)
Query Neighborhood Hits	303	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	4.57862e-28 (rank : 89)	NC score	0.726455 (rank : 26)
Query Neighborhood Hits	303	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

FRM4B_HUMAN
θ value	3.51386e-20 (rank : 90)	NC score	0.564782 (rank : 75)
Query Neighborhood Hits	303	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	4.58923e-20 (rank : 91)	NC score	0.563483 (rank : 77)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
θ value	2.97466e-19 (rank : 92)	NC score	0.557767 (rank : 79)
Query Neighborhood Hits	303	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	3.88503e-19 (rank : 93)	NC score	0.558314 (rank : 78)
Query Neighborhood Hits	303	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD6_HUMAN
θ value	1.86753e-13 (rank : 94)	NC score	0.493270 (rank : 93)
Query Neighborhood Hits	303	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
θ value	4.16044e-13 (rank : 95)	NC score	0.499076 (rank : 92)
Query Neighborhood Hits	303	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

TLN1_HUMAN
θ value	2.98157e-11 (rank : 96)	NC score	0.314251 (rank : 97)
Query Neighborhood Hits	303	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	2.98157e-11 (rank : 97)	NC score	0.311853 (rank : 98)
Query Neighborhood Hits	303	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
θ value	1.25267e-09 (rank : 98)	NC score	0.307406 (rank : 100)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	2.13673e-09 (rank : 99)	NC score	0.310671 (rank : 99)
Query Neighborhood Hits	303	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

LIN7C_HUMAN
θ value	2.79066e-09 (rank : 100)	NC score	0.212374 (rank : 105)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	2.79066e-09 (rank : 101)	NC score	0.212374 (rank : 106)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

FRMD1_HUMAN
θ value	6.21693e-09 (rank : 102)	NC score	0.481335 (rank : 95)
Query Neighborhood Hits	303	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

SNTB2_HUMAN
θ value	1.38499e-08 (rank : 103)	NC score	0.209782 (rank : 107)
Query Neighborhood Hits	303	Target Neighborhood Hits	180	Shared Neighborhood Hits	117
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	1.80886e-08 (rank : 104)	NC score	0.209752 (rank : 108)
Query Neighborhood Hits	303	Target Neighborhood Hits	181	Shared Neighborhood Hits	118
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB1_HUMAN
θ value	4.45536e-07 (rank : 105)	NC score	0.200778 (rank : 113)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	109
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	4.45536e-07 (rank : 106)	NC score	0.200650 (rank : 115)
Query Neighborhood Hits	303	Target Neighborhood Hits	160	Shared Neighborhood Hits	109
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTA1_HUMAN
θ value	9.92553e-07 (rank : 107)	NC score	0.200436 (rank : 116)
Query Neighborhood Hits	303	Target Neighborhood Hits	186	Shared Neighborhood Hits	109
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	1.29631e-06 (rank : 108)	NC score	0.200701 (rank : 114)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	109
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

LIN7B_HUMAN
θ value	1.69304e-06 (rank : 109)	NC score	0.209225 (rank : 109)
Query Neighborhood Hits	303	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
θ value	1.69304e-06 (rank : 110)	NC score	0.209101 (rank : 110)
Query Neighborhood Hits	303	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

MAGI2_HUMAN
θ value	2.88788e-06 (rank : 111)	NC score	0.169998 (rank : 130)
Query Neighborhood Hits	303	Target Neighborhood Hits	373	Shared Neighborhood Hits	126
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	3.77169e-06 (rank : 112)	NC score	0.169928 (rank : 131)
Query Neighborhood Hits	303	Target Neighborhood Hits	370	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

GOPC_HUMAN
θ value	1.09739e-05 (rank : 113)	NC score	0.192312 (rank : 119)
Query Neighborhood Hits	303	Target Neighborhood Hits	377	Shared Neighborhood Hits	120
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	1.09739e-05 (rank : 114)	NC score	0.194311 (rank : 117)
Query Neighborhood Hits	303	Target Neighborhood Hits	323	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LIN7A_HUMAN
θ value	1.87187e-05 (rank : 115)	NC score	0.208560 (rank : 111)
Query Neighborhood Hits	303	Target Neighborhood Hits	193	Shared Neighborhood Hits	118
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	1.87187e-05 (rank : 116)	NC score	0.208528 (rank : 112)
Query Neighborhood Hits	303	Target Neighborhood Hits	193	Shared Neighborhood Hits	118
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

SNTG2_MOUSE
θ value	3.19293e-05 (rank : 117)	NC score	0.188703 (rank : 121)
Query Neighborhood Hits	303	Target Neighborhood Hits	176	Shared Neighborhood Hits	114
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDZ11_MOUSE
θ value	0.000158464 (rank : 118)	NC score	0.214755 (rank : 103)
Query Neighborhood Hits	303	Target Neighborhood Hits	154	Shared Neighborhood Hits	110
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LDB3_HUMAN
θ value	0.00020696 (rank : 119)	NC score	0.094208 (rank : 214)
Query Neighborhood Hits	303	Target Neighborhood Hits	497	Shared Neighborhood Hits	103
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	0.00020696 (rank : 120)	NC score	0.096152 (rank : 211)
Query Neighborhood Hits	303	Target Neighborhood Hits	510	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDZ11_HUMAN
θ value	0.00020696 (rank : 121)	NC score	0.213400 (rank : 104)
Query Neighborhood Hits	303	Target Neighborhood Hits	160	Shared Neighborhood Hits	112
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

WHRN_MOUSE
θ value	0.000270298 (rank : 122)	NC score	0.182647 (rank : 125)
Query Neighborhood Hits	303	Target Neighborhood Hits	412	Shared Neighborhood Hits	128
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

DLG4_HUMAN
θ value	0.000461057 (rank : 123)	NC score	0.150584 (rank : 151)
Query Neighborhood Hits	303	Target Neighborhood Hits	286	Shared Neighborhood Hits	114
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.000461057 (rank : 124)	NC score	0.150741 (rank : 150)
Query Neighborhood Hits	303	Target Neighborhood Hits	282	Shared Neighborhood Hits	114
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

SNTG1_MOUSE
θ value	0.000602161 (rank : 125)	NC score	0.186539 (rank : 123)
Query Neighborhood Hits	303	Target Neighborhood Hits	179	Shared Neighborhood Hits	115
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

MAGI1_MOUSE
θ value	0.000786445 (rank : 126)	NC score	0.166323 (rank : 132)
Query Neighborhood Hits	303	Target Neighborhood Hits	403	Shared Neighborhood Hits	126
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

SNTG1_HUMAN
θ value	0.000786445 (rank : 127)	NC score	0.185971 (rank : 124)
Query Neighborhood Hits	303	Target Neighborhood Hits	181	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG2_HUMAN
θ value	0.000786445 (rank : 128)	NC score	0.186991 (rank : 122)
Query Neighborhood Hits	303	Target Neighborhood Hits	191	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDZD7_HUMAN
θ value	0.00102713 (rank : 129)	NC score	0.192541 (rank : 118)
Query Neighborhood Hits	303	Target Neighborhood Hits	181	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

DLG2_HUMAN
θ value	0.00134147 (rank : 130)	NC score	0.146829 (rank : 156)
Query Neighborhood Hits	303	Target Neighborhood Hits	279	Shared Neighborhood Hits	112
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	0.00134147 (rank : 131)	NC score	0.147255 (rank : 155)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	110
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PDZD1_MOUSE
θ value	0.00134147 (rank : 132)	NC score	0.160267 (rank : 139)
Query Neighborhood Hits	303	Target Neighborhood Hits	191	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SYNP2_MOUSE
θ value	0.00134147 (rank : 133)	NC score	0.131281 (rank : 172)
Query Neighborhood Hits	303	Target Neighborhood Hits	252	Shared Neighborhood Hits	103
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

LAP4_MOUSE
θ value	0.00175202 (rank : 134)	NC score	0.106789 (rank : 199)
Query Neighborhood Hits	303	Target Neighborhood Hits	590	Shared Neighborhood Hits	123
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MAGI1_HUMAN
θ value	0.00175202 (rank : 135)	NC score	0.165871 (rank : 133)
Query Neighborhood Hits	303	Target Neighborhood Hits	388	Shared Neighborhood Hits	124
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MPDZ_MOUSE
θ value	0.00175202 (rank : 136)	NC score	0.161878 (rank : 137)
Query Neighborhood Hits	303	Target Neighborhood Hits	298	Shared Neighborhood Hits	121
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NHRF2_MOUSE
θ value	0.00175202 (rank : 137)	NC score	0.159692 (rank : 140)
Query Neighborhood Hits	303	Target Neighborhood Hits	194	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDLI1_MOUSE
θ value	0.00175202 (rank : 138)	NC score	0.118445 (rank : 186)
Query Neighborhood Hits	303	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

WHRN_HUMAN
θ value	0.00175202 (rank : 139)	NC score	0.179858 (rank : 126)
Query Neighborhood Hits	303	Target Neighborhood Hits	325	Shared Neighborhood Hits	122
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

NHRF2_HUMAN
θ value	0.00228821 (rank : 140)	NC score	0.162233 (rank : 136)
Query Neighborhood Hits	303	Target Neighborhood Hits	197	Shared Neighborhood Hits	115
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

SYNP2_HUMAN
θ value	0.00228821 (rank : 141)	NC score	0.117198 (rank : 189)
Query Neighborhood Hits	303	Target Neighborhood Hits	323	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ZO3_MOUSE
θ value	0.00228821 (rank : 142)	NC score	0.143792 (rank : 159)
Query Neighborhood Hits	303	Target Neighborhood Hits	224	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

TX1B3_HUMAN
θ value	0.00298849 (rank : 143)	NC score	0.173458 (rank : 128)
Query Neighborhood Hits	303	Target Neighborhood Hits	161	Shared Neighborhood Hits	106
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.00298849 (rank : 144)	NC score	0.173552 (rank : 127)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	106
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

DLG1_MOUSE
θ value	0.00390308 (rank : 145)	NC score	0.144209 (rank : 158)
Query Neighborhood Hits	303	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG3_HUMAN
θ value	0.00390308 (rank : 146)	NC score	0.147475 (rank : 154)
Query Neighborhood Hits	303	Target Neighborhood Hits	269	Shared Neighborhood Hits	114
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	0.00390308 (rank : 147)	NC score	0.147594 (rank : 152)
Query Neighborhood Hits	303	Target Neighborhood Hits	274	Shared Neighborhood Hits	113
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_HUMAN
θ value	0.00665767 (rank : 148)	NC score	0.147592 (rank : 153)
Query Neighborhood Hits	303	Target Neighborhood Hits	290	Shared Neighborhood Hits	119
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

MPDZ_HUMAN
θ value	0.00665767 (rank : 149)	NC score	0.158726 (rank : 141)
Query Neighborhood Hits	303	Target Neighborhood Hits	261	Shared Neighborhood Hits	117
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PDLI1_HUMAN
θ value	0.00665767 (rank : 150)	NC score	0.112634 (rank : 194)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	86
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

ZO2_MOUSE
θ value	0.00665767 (rank : 151)	NC score	0.134653 (rank : 170)
Query Neighborhood Hits	303	Target Neighborhood Hits	296	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PDZD1_HUMAN
θ value	0.00869519 (rank : 152)	NC score	0.155076 (rank : 143)
Query Neighborhood Hits	303	Target Neighborhood Hits	190	Shared Neighborhood Hits	111
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ZO2_HUMAN
θ value	0.00869519 (rank : 153)	NC score	0.138427 (rank : 164)
Query Neighborhood Hits	303	Target Neighborhood Hits	289	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

NHERF_HUMAN
θ value	0.0148317 (rank : 154)	NC score	0.161254 (rank : 138)
Query Neighborhood Hits	303	Target Neighborhood Hits	190	Shared Neighborhood Hits	118
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ZO3_HUMAN
θ value	0.0148317 (rank : 155)	NC score	0.139539 (rank : 162)
Query Neighborhood Hits	303	Target Neighborhood Hits	219	Shared Neighborhood Hits	111
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LNX2_HUMAN
θ value	0.0193708 (rank : 156)	NC score	0.139482 (rank : 163)
Query Neighborhood Hits	303	Target Neighborhood Hits	389	Shared Neighborhood Hits	120
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PZRN3_HUMAN
θ value	0.0193708 (rank : 157)	NC score	0.123261 (rank : 183)
Query Neighborhood Hits	303	Target Neighborhood Hits	461	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TP4A2_HUMAN
θ value	0.0193708 (rank : 158)	NC score	0.102677 (rank : 204)
Query Neighborhood Hits	303	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	0.0193708 (rank : 159)	NC score	0.102677 (rank : 205)
Query Neighborhood Hits	303	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

LAP4_HUMAN
θ value	0.0252991 (rank : 160)	NC score	0.105490 (rank : 201)
Query Neighborhood Hits	303	Target Neighborhood Hits	608	Shared Neighborhood Hits	124
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PDLI3_HUMAN
θ value	0.0252991 (rank : 161)	NC score	0.118180 (rank : 187)
Query Neighborhood Hits	303	Target Neighborhood Hits	199	Shared Neighborhood Hits	99
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

RHPN1_HUMAN
θ value	0.0252991 (rank : 162)	NC score	0.135781 (rank : 166)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GRASP_HUMAN
θ value	0.0330416 (rank : 163)	NC score	0.129942 (rank : 173)
Query Neighborhood Hits	303	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LNX2_MOUSE
θ value	0.0330416 (rank : 164)	NC score	0.141198 (rank : 161)
Query Neighborhood Hits	303	Target Neighborhood Hits	407	Shared Neighborhood Hits	121
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MYO7A_MOUSE
θ value	0.0330416 (rank : 165)	NC score	0.038079 (rank : 330)
Query Neighborhood Hits	303	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

NHERF_MOUSE
θ value	0.0330416 (rank : 166)	NC score	0.162599 (rank : 135)
Query Neighborhood Hits	303	Target Neighborhood Hits	195	Shared Neighborhood Hits	118
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDLI3_MOUSE
θ value	0.0330416 (rank : 167)	NC score	0.115595 (rank : 192)
Query Neighborhood Hits	303	Target Neighborhood Hits	197	Shared Neighborhood Hits	95
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PAR3L_HUMAN
θ value	0.0431538 (rank : 168)	NC score	0.146577 (rank : 157)
Query Neighborhood Hits	303	Target Neighborhood Hits	297	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PZRN3_MOUSE
θ value	0.0431538 (rank : 169)	NC score	0.122148 (rank : 184)
Query Neighborhood Hits	303	Target Neighborhood Hits	447	Shared Neighborhood Hits	101
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SYJ2B_HUMAN
θ value	0.0431538 (rank : 170)	NC score	0.189871 (rank : 120)
Query Neighborhood Hits	303	Target Neighborhood Hits	162	Shared Neighborhood Hits	109
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

USH1C_HUMAN
θ value	0.0563607 (rank : 171)	NC score	0.171885 (rank : 129)
Query Neighborhood Hits	303	Target Neighborhood Hits	327	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.0563607 (rank : 172)	NC score	0.163751 (rank : 134)
Query Neighborhood Hits	303	Target Neighborhood Hits	557	Shared Neighborhood Hits	132
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GRASP_MOUSE
θ value	0.0736092 (rank : 173)	NC score	0.127629 (rank : 176)
Query Neighborhood Hits	303	Target Neighborhood Hits	131	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LRRC7_HUMAN
θ value	0.0736092 (rank : 174)	NC score	0.062038 (rank : 289)
Query Neighborhood Hits	303	Target Neighborhood Hits	423	Shared Neighborhood Hits	95
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.0736092 (rank : 175)	NC score	0.061475 (rank : 293)
Query Neighborhood Hits	303	Target Neighborhood Hits	416	Shared Neighborhood Hits	92
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PDLI7_HUMAN
θ value	0.0736092 (rank : 176)	NC score	0.075299 (rank : 240)
Query Neighborhood Hits	303	Target Neighborhood Hits	547	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

GRIP1_HUMAN
θ value	0.0961366 (rank : 177)	NC score	0.151505 (rank : 149)
Query Neighborhood Hits	303	Target Neighborhood Hits	231	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	0.0961366 (rank : 178)	NC score	0.151669 (rank : 148)
Query Neighborhood Hits	303	Target Neighborhood Hits	241	Shared Neighborhood Hits	120
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MYO7A_HUMAN
θ value	0.0961366 (rank : 179)	NC score	0.037831 (rank : 331)
Query Neighborhood Hits	303	Target Neighborhood Hits	209	Shared Neighborhood Hits	27
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

PDLI7_MOUSE
θ value	0.0961366 (rank : 180)	NC score	0.074095 (rank : 242)
Query Neighborhood Hits	303	Target Neighborhood Hits	279	Shared Neighborhood Hits	85
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PO6F2_HUMAN
θ value	0.0961366 (rank : 181)	NC score	0.008806 (rank : 373)
Query Neighborhood Hits	303	Target Neighborhood Hits	618	Shared Neighborhood Hits	26
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

MLL3_MOUSE
θ value	0.125558 (rank : 182)	NC score	0.023127 (rank : 336)
Query Neighborhood Hits	303	Target Neighborhood Hits	1399	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RHPN1_MOUSE
θ value	0.125558 (rank : 183)	NC score	0.135715 (rank : 167)
Query Neighborhood Hits	303	Target Neighborhood Hits	154	Shared Neighborhood Hits	104
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

TM131_MOUSE
θ value	0.125558 (rank : 184)	NC score	0.021671 (rank : 338)
Query Neighborhood Hits	303	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

GRIP2_HUMAN
θ value	0.163984 (rank : 185)	NC score	0.154642 (rank : 145)
Query Neighborhood Hits	303	Target Neighborhood Hits	256	Shared Neighborhood Hits	124
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

ZO1_HUMAN
θ value	0.163984 (rank : 186)	NC score	0.127553 (rank : 177)
Query Neighborhood Hits	303	Target Neighborhood Hits	474	Shared Neighborhood Hits	125
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PO6F2_MOUSE
θ value	0.21417 (rank : 187)	NC score	0.007469 (rank : 379)
Query Neighborhood Hits	303	Target Neighborhood Hits	639	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RFIP1_HUMAN
θ value	0.21417 (rank : 188)	NC score	0.013434 (rank : 355)
Query Neighborhood Hits	303	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

WASF3_MOUSE
θ value	0.21417 (rank : 189)	NC score	0.013328 (rank : 356)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ZO1_MOUSE
θ value	0.21417 (rank : 190)	NC score	0.127382 (rank : 178)
Query Neighborhood Hits	303	Target Neighborhood Hits	453	Shared Neighborhood Hits	123
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ARHGB_HUMAN
θ value	0.279714 (rank : 191)	NC score	0.098248 (rank : 207)
Query Neighborhood Hits	303	Target Neighborhood Hits	375	Shared Neighborhood Hits	115
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PZRN4_HUMAN
θ value	0.279714 (rank : 192)	NC score	0.125284 (rank : 181)
Query Neighborhood Hits	303	Target Neighborhood Hits	438	Shared Neighborhood Hits	99
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RGS12_HUMAN
θ value	0.279714 (rank : 193)	NC score	0.080831 (rank : 226)
Query Neighborhood Hits	303	Target Neighborhood Hits	333	Shared Neighborhood Hits	105
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

TP4A1_HUMAN
θ value	0.279714 (rank : 194)	NC score	0.116130 (rank : 190)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	0.279714 (rank : 195)	NC score	0.116130 (rank : 191)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

APXL_HUMAN
θ value	0.365318 (rank : 196)	NC score	0.113159 (rank : 193)
Query Neighborhood Hits	303	Target Neighborhood Hits	553	Shared Neighborhood Hits	92
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CC14B_MOUSE
θ value	0.365318 (rank : 197)	NC score	0.119949 (rank : 185)
Query Neighborhood Hits	303	Target Neighborhood Hits	103	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PDLI4_HUMAN
θ value	0.365318 (rank : 198)	NC score	0.107043 (rank : 197)
Query Neighborhood Hits	303	Target Neighborhood Hits	245	Shared Neighborhood Hits	93
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	0.365318 (rank : 199)	NC score	0.107535 (rank : 196)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RC3H1_HUMAN
θ value	0.365318 (rank : 200)	NC score	0.010213 (rank : 369)
Query Neighborhood Hits	303	Target Neighborhood Hits	433	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SSBP4_HUMAN
θ value	0.365318 (rank : 201)	NC score	0.015289 (rank : 349)
Query Neighborhood Hits	303	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STON2_HUMAN
θ value	0.365318 (rank : 202)	NC score	0.012022 (rank : 364)
Query Neighborhood Hits	303	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

JIP1_HUMAN
θ value	0.47712 (rank : 203)	NC score	0.011399 (rank : 365)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LIRB4_HUMAN
θ value	0.47712 (rank : 204)	NC score	0.003937 (rank : 391)
Query Neighborhood Hits	303	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

PDLI2_MOUSE
θ value	0.47712 (rank : 205)	NC score	0.133062 (rank : 171)
Query Neighborhood Hits	303	Target Neighborhood Hits	220	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

RPGF6_HUMAN
θ value	0.47712 (rank : 206)	NC score	0.096541 (rank : 210)
Query Neighborhood Hits	303	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

M3K12_HUMAN
θ value	0.62314 (rank : 207)	NC score	-0.009266 (rank : 405)
Query Neighborhood Hits	303	Target Neighborhood Hits	940	Shared Neighborhood Hits	8
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MARK2_MOUSE
θ value	0.62314 (rank : 208)	NC score	-0.009242 (rank : 404)
Query Neighborhood Hits	303	Target Neighborhood Hits	1018	Shared Neighborhood Hits	19
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

RIMS1_HUMAN
θ value	0.62314 (rank : 209)	NC score	0.052773 (rank : 318)
Query Neighborhood Hits	303	Target Neighborhood Hits	437	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SSBP3_HUMAN
θ value	0.62314 (rank : 210)	NC score	0.017799 (rank : 342)
Query Neighborhood Hits	303	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	0.62314 (rank : 211)	NC score	0.017799 (rank : 343)
Query Neighborhood Hits	303	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

SYP2L_HUMAN
θ value	0.62314 (rank : 212)	NC score	0.127348 (rank : 179)
Query Neighborhood Hits	303	Target Neighborhood Hits	400	Shared Neighborhood Hits	108
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	0.62314 (rank : 213)	NC score	0.103139 (rank : 203)
Query Neighborhood Hits	303	Target Neighborhood Hits	289	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CBP_MOUSE
θ value	0.813845 (rank : 214)	NC score	0.015790 (rank : 346)
Query Neighborhood Hits	303	Target Neighborhood Hits	1051	Shared Neighborhood Hits	44
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

IL16_MOUSE
θ value	0.813845 (rank : 215)	NC score	0.154477 (rank : 146)
Query Neighborhood Hits	303	Target Neighborhood Hits	189	Shared Neighborhood Hits	100
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LAP2_MOUSE
θ value	0.813845 (rank : 216)	NC score	0.053374 (rank : 316)
Query Neighborhood Hits	303	Target Neighborhood Hits	482	Shared Neighborhood Hits	86
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

NOTC1_HUMAN
θ value	0.813845 (rank : 217)	NC score	-0.005192 (rank : 402)
Query Neighborhood Hits	303	Target Neighborhood Hits	906	Shared Neighborhood Hits	10
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PDZD2_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.141543 (rank : 160)
Query Neighborhood Hits	303	Target Neighborhood Hits	772	Shared Neighborhood Hits	136
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CUTL2_HUMAN
θ value	1.06291 (rank : 219)	NC score	0.015614 (rank : 348)
Query Neighborhood Hits	303	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DUS11_MOUSE
θ value	1.06291 (rank : 220)	NC score	0.034368 (rank : 334)
Query Neighborhood Hits	303	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

IL16_HUMAN
θ value	1.06291 (rank : 221)	NC score	0.157552 (rank : 142)
Query Neighborhood Hits	303	Target Neighborhood Hits	207	Shared Neighborhood Hits	106
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

INADL_HUMAN
θ value	1.06291 (rank : 222)	NC score	0.153319 (rank : 147)
Query Neighborhood Hits	303	Target Neighborhood Hits	260	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

PRGC1_MOUSE
θ value	1.06291 (rank : 223)	NC score	0.012512 (rank : 361)
Query Neighborhood Hits	303	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

AFF1_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.012045 (rank : 363)
Query Neighborhood Hits	303	Target Neighborhood Hits	506	Shared Neighborhood Hits	31
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CC14B_HUMAN
θ value	1.38821 (rank : 225)	NC score	0.117562 (rank : 188)
Query Neighborhood Hits	303	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_HUMAN
θ value	1.38821 (rank : 226)	NC score	0.223961 (rank : 102)
Query Neighborhood Hits	303	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

KBTBA_HUMAN
θ value	1.38821 (rank : 227)	NC score	0.000539 (rank : 396)
Query Neighborhood Hits	303	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

LAP2_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.056688 (rank : 306)
Query Neighborhood Hits	303	Target Neighborhood Hits	499	Shared Neighborhood Hits	91
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SALL4_HUMAN
θ value	1.38821 (rank : 229)	NC score	-0.008494 (rank : 403)
Query Neighborhood Hits	303	Target Neighborhood Hits	799	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJQ4	Gene names	SALL4
Domain Architecture
Description	Sal-like protein 4 (Zinc finger protein SALL4).

SHAN1_HUMAN
θ value	1.38821 (rank : 230)	NC score	0.035656 (rank : 332)
Query Neighborhood Hits	303	Target Neighborhood Hits	1041	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TP4A3_HUMAN
θ value	1.38821 (rank : 231)	NC score	0.095450 (rank : 212)
Query Neighborhood Hits	303	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TPTE2_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.034864 (rank : 333)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

BAG4_HUMAN
θ value	1.81305 (rank : 233)	NC score	0.013212 (rank : 357)
Query Neighborhood Hits	303	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

BAG4_MOUSE
θ value	1.81305 (rank : 234)	NC score	0.013583 (rank : 353)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CI61, Q3TRL9, Q91VT5, Q9CWG2	Gene names	Bag4, Sodd
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CBP_HUMAN
θ value	1.81305 (rank : 235)	NC score	0.019966 (rank : 339)
Query Neighborhood Hits	303	Target Neighborhood Hits	941	Shared Neighborhood Hits	47
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDIT3_MOUSE
θ value	1.81305 (rank : 236)	NC score	0.013122 (rank : 359)
Query Neighborhood Hits	303	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	P35639, Q91YW9	Gene names	Ddit3, Chop, Gadd153
Domain Architecture	No domain graphic available
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

INADL_MOUSE
θ value	1.81305 (rank : 237)	NC score	0.154966 (rank : 144)
Query Neighborhood Hits	303	Target Neighborhood Hits	290	Shared Neighborhood Hits	122
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LARP1_HUMAN
θ value	1.81305 (rank : 238)	NC score	0.010562 (rank : 367)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

NOTC1_MOUSE
θ value	1.81305 (rank : 239)	NC score	-0.004823 (rank : 401)
Query Neighborhood Hits	303	Target Neighborhood Hits	916	Shared Neighborhood Hits	15
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NR4A3_MOUSE
θ value	1.81305 (rank : 240)	NC score	-0.000496 (rank : 398)
Query Neighborhood Hits	303	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

PRGC1_HUMAN
θ value	1.81305 (rank : 241)	NC score	0.012467 (rank : 362)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

SARDH_MOUSE
θ value	1.81305 (rank : 242)	NC score	0.007090 (rank : 380)
Query Neighborhood Hits	303	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LB7	Gene names	Sardh
Domain Architecture	No domain graphic available
Description	Sarcosine dehydrogenase, mitochondrial precursor (EC 1.5.99.1) (SarDH).

YLPM1_HUMAN
θ value	1.81305 (rank : 243)	NC score	0.010988 (rank : 366)
Query Neighborhood Hits	303	Target Neighborhood Hits	670	Shared Neighborhood Hits	36
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CC14A_MOUSE
θ value	2.36792 (rank : 244)	NC score	0.106752 (rank : 200)
Query Neighborhood Hits	303	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

DUS23_MOUSE
θ value	2.36792 (rank : 245)	NC score	0.233035 (rank : 101)
Query Neighborhood Hits	303	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

MLL3_HUMAN
θ value	2.36792 (rank : 246)	NC score	0.022433 (rank : 337)
Query Neighborhood Hits	303	Target Neighborhood Hits	1644	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PDLI5_MOUSE
θ value	2.36792 (rank : 247)	NC score	0.073249 (rank : 246)
Query Neighborhood Hits	303	Target Neighborhood Hits	287	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

ATX2L_MOUSE
θ value	3.0926 (rank : 248)	NC score	0.015641 (rank : 347)
Query Neighborhood Hits	303	Target Neighborhood Hits	401	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CC14A_HUMAN
θ value	3.0926 (rank : 249)	NC score	0.104259 (rank : 202)
Query Neighborhood Hits	303	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CD44_MOUSE
θ value	3.0926 (rank : 250)	NC score	0.008065 (rank : 376)
Query Neighborhood Hits	303	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

CT151_HUMAN
θ value	3.0926 (rank : 251)	NC score	0.012918 (rank : 360)
Query Neighborhood Hits	303	Target Neighborhood Hits	382	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

EM55_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.062695 (rank : 282)
Query Neighborhood Hits	303	Target Neighborhood Hits	228	Shared Neighborhood Hits	77
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EVI2B_MOUSE
θ value	3.0926 (rank : 253)	NC score	0.008203 (rank : 375)
Query Neighborhood Hits	303	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

NKTR_HUMAN
θ value	3.0926 (rank : 254)	NC score	0.004386 (rank : 389)
Query Neighborhood Hits	303	Target Neighborhood Hits	658	Shared Neighborhood Hits	23
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NOS1_HUMAN
θ value	3.0926 (rank : 255)	NC score	0.072166 (rank : 250)
Query Neighborhood Hits	303	Target Neighborhood Hits	218	Shared Neighborhood Hits	93
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PARD3_HUMAN
θ value	3.0926 (rank : 256)	NC score	0.137218 (rank : 165)
Query Neighborhood Hits	303	Target Neighborhood Hits	312	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDE8A_MOUSE
θ value	3.0926 (rank : 257)	NC score	0.002278 (rank : 394)
Query Neighborhood Hits	303	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

TRAF7_HUMAN
θ value	3.0926 (rank : 258)	NC score	0.002203 (rank : 395)
Query Neighborhood Hits	303	Target Neighborhood Hits	482	Shared Neighborhood Hits	12
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

WTAP_HUMAN
θ value	3.0926 (rank : 259)	NC score	0.009337 (rank : 370)
Query Neighborhood Hits	303	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

WTAP_MOUSE
θ value	3.0926 (rank : 260)	NC score	0.010503 (rank : 368)
Query Neighborhood Hits	303	Target Neighborhood Hits	250	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

ATX2L_HUMAN
θ value	4.03905 (rank : 261)	NC score	0.013166 (rank : 358)
Query Neighborhood Hits	303	Target Neighborhood Hits	443	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

GLYG2_HUMAN
θ value	4.03905 (rank : 262)	NC score	0.005889 (rank : 384)
Query Neighborhood Hits	303	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

JIP1_MOUSE
θ value	4.03905 (rank : 263)	NC score	0.008456 (rank : 374)
Query Neighborhood Hits	303	Target Neighborhood Hits	259	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MARK1_HUMAN
θ value	4.03905 (rank : 264)	NC score	-0.009966 (rank : 406)
Query Neighborhood Hits	303	Target Neighborhood Hits	887	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).

MY18A_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.026181 (rank : 335)
Query Neighborhood Hits	303	Target Neighborhood Hits	1929	Shared Neighborhood Hits	105
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NCOR1_MOUSE
θ value	4.03905 (rank : 266)	NC score	0.016636 (rank : 344)
Query Neighborhood Hits	303	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PAR6G_MOUSE
θ value	4.03905 (rank : 267)	NC score	0.072191 (rank : 249)
Query Neighborhood Hits	303	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDLI2_HUMAN
θ value	4.03905 (rank : 268)	NC score	0.127730 (rank : 175)
Query Neighborhood Hits	303	Target Neighborhood Hits	245	Shared Neighborhood Hits	110
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

UBP2L_HUMAN
θ value	4.03905 (rank : 269)	NC score	0.013529 (rank : 354)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

UBP2L_MOUSE
θ value	4.03905 (rank : 270)	NC score	0.013943 (rank : 352)
Query Neighborhood Hits	303	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

ACE_MOUSE
θ value	5.27518 (rank : 271)	NC score	0.004205 (rank : 390)
Query Neighborhood Hits	303	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

APBA1_HUMAN
θ value	5.27518 (rank : 272)	NC score	0.069393 (rank : 260)
Query Neighborhood Hits	303	Target Neighborhood Hits	325	Shared Neighborhood Hits	90
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

BSN_HUMAN
θ value	5.27518 (rank : 273)	NC score	0.019870 (rank : 340)
Query Neighborhood Hits	303	Target Neighborhood Hits	1537	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

HUWE1_HUMAN
θ value	5.27518 (rank : 274)	NC score	0.005604 (rank : 386)
Query Neighborhood Hits	303	Target Neighborhood Hits	443	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

LNX1_MOUSE
θ value	5.27518 (rank : 275)	NC score	0.128832 (rank : 174)
Query Neighborhood Hits	303	Target Neighborhood Hits	377	Shared Neighborhood Hits	113
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MRIP_HUMAN
θ value	5.27518 (rank : 276)	NC score	-0.000135 (rank : 397)
Query Neighborhood Hits	303	Target Neighborhood Hits	578	Shared Neighborhood Hits	12
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PARD3_MOUSE
θ value	5.27518 (rank : 277)	NC score	0.135207 (rank : 169)
Query Neighborhood Hits	303	Target Neighborhood Hits	290	Shared Neighborhood Hits	106
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PRG4_HUMAN
θ value	5.27518 (rank : 278)	NC score	0.009135 (rank : 372)
Query Neighborhood Hits	303	Target Neighborhood Hits	764	Shared Neighborhood Hits	36
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RAPH1_HUMAN
θ value	5.27518 (rank : 279)	NC score	0.009242 (rank : 371)
Query Neighborhood Hits	303	Target Neighborhood Hits	593	Shared Neighborhood Hits	35
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RARB_MOUSE
θ value	5.27518 (rank : 280)	NC score	-0.001839 (rank : 399)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

SDCB2_HUMAN
θ value	5.27518 (rank : 281)	NC score	0.071337 (rank : 253)
Query Neighborhood Hits	303	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SRTD2_HUMAN
θ value	5.27518 (rank : 282)	NC score	0.007770 (rank : 378)
Query Neighborhood Hits	303	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

CARD6_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.006164 (rank : 382)
Query Neighborhood Hits	303	Target Neighborhood Hits	145	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

HUWE1_MOUSE
θ value	6.88961 (rank : 284)	NC score	0.005540 (rank : 387)
Query Neighborhood Hits	303	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

NHS_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.005855 (rank : 385)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PCLO_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.014615 (rank : 350)
Query Neighborhood Hits	303	Target Neighborhood Hits	2046	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PDLI5_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.071890 (rank : 252)
Query Neighborhood Hits	303	Target Neighborhood Hits	322	Shared Neighborhood Hits	97
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SOS1_HUMAN
θ value	6.88961 (rank : 288)	NC score	0.018771 (rank : 341)
Query Neighborhood Hits	303	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

TENX_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.038721 (rank : 329)
Query Neighborhood Hits	303	Target Neighborhood Hits	789	Shared Neighborhood Hits	24
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TP4A3_MOUSE
θ value	6.88961 (rank : 290)	NC score	0.085730 (rank : 220)
Query Neighborhood Hits	303	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

ACE_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.003698 (rank : 392)
Query Neighborhood Hits	303	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ANR41_HUMAN
θ value	8.99809 (rank : 292)	NC score	-0.002696 (rank : 400)
Query Neighborhood Hits	303	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

BAZ2B_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.006053 (rank : 383)
Query Neighborhood Hits	303	Target Neighborhood Hits	803	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

GLU2B_MOUSE
θ value	8.99809 (rank : 294)	NC score	0.006331 (rank : 381)
Query Neighborhood Hits	303	Target Neighborhood Hits	357	Shared Neighborhood Hits	9
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MBD5_HUMAN
θ value	8.99809 (rank : 295)	NC score	0.004824 (rank : 388)
Query Neighborhood Hits	303	Target Neighborhood Hits	176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

PAR6G_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.072091 (rank : 251)
Query Neighborhood Hits	303	Target Neighborhood Hits	159	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PICK1_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.082400 (rank : 224)
Query Neighborhood Hits	303	Target Neighborhood Hits	132	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PSCBP_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.086971 (rank : 218)
Query Neighborhood Hits	303	Target Neighborhood Hits	123	Shared Neighborhood Hits	85
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

SDCB1_MOUSE
θ value	8.99809 (rank : 299)	NC score	0.082716 (rank : 223)
Query Neighborhood Hits	303	Target Neighborhood Hits	144	Shared Neighborhood Hits	96
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SMG7_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.002734 (rank : 393)
Query Neighborhood Hits	303	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

SOS1_MOUSE
θ value	8.99809 (rank : 301)	NC score	0.016421 (rank : 345)
Query Neighborhood Hits	303	Target Neighborhood Hits	281	Shared Neighborhood Hits	13
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SRRM1_MOUSE
θ value	8.99809 (rank : 302)	NC score	0.014378 (rank : 351)
Query Neighborhood Hits	303	Target Neighborhood Hits	966	Shared Neighborhood Hits	49
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TM108_MOUSE
θ value	8.99809 (rank : 303)	NC score	0.007776 (rank : 377)
Query Neighborhood Hits	303	Target Neighborhood Hits	336	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

AFAD_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.093063 (rank : 215)
Query Neighborhood Hits	303	Target Neighborhood Hits	689	Shared Neighborhood Hits	101
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

APBA2_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.064982 (rank : 271)
Query Neighborhood Hits	303	Target Neighborhood Hits	220	Shared Neighborhood Hits	87
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.064460 (rank : 274)
Query Neighborhood Hits	303	Target Neighborhood Hits	219	Shared Neighborhood Hits	85
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.063716 (rank : 276)
Query Neighborhood Hits	303	Target Neighborhood Hits	201	Shared Neighborhood Hits	77
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.062481 (rank : 285)
Query Neighborhood Hits	303	Target Neighborhood Hits	174	Shared Neighborhood Hits	80
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGC_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.084240 (rank : 221)
Query Neighborhood Hits	303	Target Neighborhood Hits	351	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.083309 (rank : 222)
Query Neighborhood Hits	303	Target Neighborhood Hits	344	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CA106_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.059176 (rank : 296)
Query Neighborhood Hits	303	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.058423 (rank : 299)
Query Neighborhood Hits	303	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CDKN3_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.069935 (rank : 257)
Query Neighborhood Hits	303	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

CNTN1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.050357 (rank : 328)
Query Neighborhood Hits	303	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.051469 (rank : 325)
Query Neighborhood Hits	303	Target Neighborhood Hits	422	Shared Neighborhood Hits	13
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.054323 (rank : 313)
Query Neighborhood Hits	303	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.054187 (rank : 314)
Query Neighborhood Hits	303	Target Neighborhood Hits	450	Shared Neighborhood Hits	14
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.056140 (rank : 308)
Query Neighborhood Hits	303	Target Neighborhood Hits	446	Shared Neighborhood Hits	16
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.054832 (rank : 311)
Query Neighborhood Hits	303	Target Neighborhood Hits	434	Shared Neighborhood Hits	15
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CO7A1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.054680 (rank : 312)
Query Neighborhood Hits	303	Target Neighborhood Hits	807	Shared Neighborhood Hits	32
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.069344 (rank : 261)
Query Neighborhood Hits	303	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.070853 (rank : 254)
Query Neighborhood Hits	303	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.051498 (rank : 324)
Query Neighborhood Hits	303	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.057779 (rank : 303)
Query Neighborhood Hits	303	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.079672 (rank : 228)
Query Neighborhood Hits	303	Target Neighborhood Hits	583	Shared Neighborhood Hits	30
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.077683 (rank : 234)
Query Neighborhood Hits	303	Target Neighborhood Hits	896	Shared Neighborhood Hits	46
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DLG5_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.086592 (rank : 219)
Query Neighborhood Hits	303	Target Neighborhood Hits	1088	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DSCAM_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.057524 (rank : 305)
Query Neighborhood Hits	303	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.057529 (rank : 304)
Query Neighborhood Hits	303	Target Neighborhood Hits	589	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DVL1L_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.062737 (rank : 281)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.067056 (rank : 265)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	82
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.065347 (rank : 270)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	79
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.063048 (rank : 279)
Query Neighborhood Hits	303	Target Neighborhood Hits	223	Shared Neighborhood Hits	80
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.063311 (rank : 278)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.066614 (rank : 267)
Query Neighborhood Hits	303	Target Neighborhood Hits	194	Shared Neighborhood Hits	78
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.066143 (rank : 268)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	78
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

EM55_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.060262 (rank : 294)
Query Neighborhood Hits	303	Target Neighborhood Hits	221	Shared Neighborhood Hits	76
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

FINC_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.107688 (rank : 195)
Query Neighborhood Hits	303	Target Neighborhood Hits	302	Shared Neighborhood Hits	25
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.106800 (rank : 198)
Query Neighborhood Hits	303	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.096634 (rank : 209)
Query Neighborhood Hits	303	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.090167 (rank : 216)
Query Neighborhood Hits	303	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ITB4_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.062179 (rank : 286)
Query Neighborhood Hits	303	Target Neighborhood Hits	458	Shared Neighborhood Hits	21
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

K1849_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.096777 (rank : 208)
Query Neighborhood Hits	303	Target Neighborhood Hits	220	Shared Neighborhood Hits	94
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.099210 (rank : 206)
Query Neighborhood Hits	303	Target Neighborhood Hits	335	Shared Neighborhood Hits	100
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

KRIT1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.062582 (rank : 283)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.058484 (rank : 298)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

L1CAM_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.058271 (rank : 300)
Query Neighborhood Hits	303	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.058945 (rank : 297)
Query Neighborhood Hits	303	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LNX1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.124572 (rank : 182)
Query Neighborhood Hits	303	Target Neighborhood Hits	379	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAMC1_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.052369 (rank : 320)
Query Neighborhood Hits	303	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.053330 (rank : 317)
Query Neighborhood Hits	303	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC2_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.070665 (rank : 256)
Query Neighborhood Hits	303	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.073658 (rank : 245)
Query Neighborhood Hits	303	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDGA1_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.055676 (rank : 309)
Query Neighborhood Hits	303	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MPP2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.051688 (rank : 322)
Query Neighborhood Hits	303	Target Neighborhood Hits	173	Shared Neighborhood Hits	63
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.052212 (rank : 321)
Query Neighborhood Hits	303	Target Neighborhood Hits	189	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP3_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.069917 (rank : 258)
Query Neighborhood Hits	303	Target Neighborhood Hits	171	Shared Neighborhood Hits	77
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.070718 (rank : 255)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	77
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.079632 (rank : 229)
Query Neighborhood Hits	303	Target Neighborhood Hits	205	Shared Neighborhood Hits	85
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.068770 (rank : 263)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP5_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.072844 (rank : 248)
Query Neighborhood Hits	303	Target Neighborhood Hits	231	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.072965 (rank : 247)
Query Neighborhood Hits	303	Target Neighborhood Hits	226	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MYOM1_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.052492 (rank : 319)
Query Neighborhood Hits	303	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NEB1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.078905 (rank : 230)
Query Neighborhood Hits	303	Target Neighborhood Hits	829	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.080847 (rank : 225)
Query Neighborhood Hits	303	Target Neighborhood Hits	883	Shared Neighborhood Hits	89
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.078460 (rank : 232)
Query Neighborhood Hits	303	Target Neighborhood Hits	889	Shared Neighborhood Hits	90
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEO1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.075209 (rank : 241)
Query Neighborhood Hits	303	Target Neighborhood Hits	530	Shared Neighborhood Hits	26
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.077629 (rank : 235)
Query Neighborhood Hits	303	Target Neighborhood Hits	523	Shared Neighborhood Hits	26
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NFASC_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.050790 (rank : 327)
Query Neighborhood Hits	303	Target Neighborhood Hits	497	Shared Neighborhood Hits	20
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NOS1_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.061942 (rank : 290)
Query Neighborhood Hits	303	Target Neighborhood Hits	155	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NRCAM_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.056229 (rank : 307)
Query Neighborhood Hits	303	Target Neighborhood Hits	439	Shared Neighborhood Hits	14
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.058077 (rank : 301)
Query Neighborhood Hits	303	Target Neighborhood Hits	432	Shared Neighborhood Hits	16
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PAR6A_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.061883 (rank : 291)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.062574 (rank : 284)
Query Neighborhood Hits	303	Target Neighborhood Hits	115	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.069522 (rank : 259)
Query Neighborhood Hits	303	Target Neighborhood Hits	126	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.068999 (rank : 262)
Query Neighborhood Hits	303	Target Neighborhood Hits	128	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PDC6I_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.051586 (rank : 323)
Query Neighborhood Hits	303	Target Neighborhood Hits	275	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDZD3_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.135577 (rank : 168)
Query Neighborhood Hits	303	Target Neighborhood Hits	180	Shared Neighborhood Hits	108
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.126563 (rank : 180)
Query Neighborhood Hits	303	Target Neighborhood Hits	171	Shared Neighborhood Hits	111
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZK4_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.075811 (rank : 239)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.076837 (rank : 238)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PICK1_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.080651 (rank : 227)
Query Neighborhood Hits	303	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PSCBP_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.095272 (rank : 213)
Query Neighborhood Hits	303	Target Neighborhood Hits	118	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PTEN_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.077063 (rank : 236)
Query Neighborhood Hits	303	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.077062 (rank : 237)
Query Neighborhood Hits	303	Target Neighborhood Hits	73	Shared Neighborhood Hits	41
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

RES18_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.057854 (rank : 302)
Query Neighborhood Hits	303	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

RHPN2_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.051244 (rank : 326)
Query Neighborhood Hits	303	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RHPN2_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.062089 (rank : 287)
Query Neighborhood Hits	303	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RPGF2_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.073719 (rank : 244)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SDCB1_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.078526 (rank : 231)
Query Neighborhood Hits	303	Target Neighborhood Hits	150	Shared Neighborhood Hits	96
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB2_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.066126 (rank : 269)
Query Neighborhood Hits	303	Target Neighborhood Hits	118	Shared Neighborhood Hits	76
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDK1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.063585 (rank : 277)
Query Neighborhood Hits	303	Target Neighborhood Hits	511	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.064581 (rank : 272)
Query Neighborhood Hits	303	Target Neighborhood Hits	495	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.064475 (rank : 273)
Query Neighborhood Hits	303	Target Neighborhood Hits	495	Shared Neighborhood Hits	25
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.066999 (rank : 266)
Query Neighborhood Hits	303	Target Neighborhood Hits	480	Shared Neighborhood Hits	23
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SHAN2_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.055072 (rank : 310)
Query Neighborhood Hits	303	Target Neighborhood Hits	346	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

STXB4_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.087198 (rank : 217)
Query Neighborhood Hits	303	Target Neighborhood Hits	616	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.078441 (rank : 233)
Query Neighborhood Hits	303	Target Neighborhood Hits	629	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TARSH_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.060231 (rank : 295)
Query Neighborhood Hits	303	Target Neighborhood Hits	768	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENA_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.053713 (rank : 315)
Query Neighborhood Hits	303	Target Neighborhood Hits	631	Shared Neighborhood Hits	23
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENN_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.063032 (rank : 280)
Query Neighborhood Hits	303	Target Neighborhood Hits	453	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.074088 (rank : 243)
Query Neighborhood Hits	303	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.062053 (rank : 288)
Query Neighborhood Hits	303	Target Neighborhood Hits	526	Shared Neighborhood Hits	20
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.061822 (rank : 292)
Query Neighborhood Hits	303	Target Neighborhood Hits	531	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

USH2A_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.067439 (rank : 264)
Query Neighborhood Hits	303	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.064448 (rank : 275)
Query Neighborhood Hits	303	Target Neighborhood Hits	626	Shared Neighborhood Hits	25
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

PTN4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	303	Target Neighborhood Hits	303	Shared Neighborhood Hits	303
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.990853 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	216
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_HUMAN
NC score	0.922494 (rank : 3)	θ value	7.03111e-45 (rank : 34)
Query Neighborhood Hits	303	Target Neighborhood Hits	143	Shared Neighborhood Hits	108
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
NC score	0.922410 (rank : 4)	θ value	5.38352e-45 (rank : 33)
Query Neighborhood Hits	303	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_MOUSE
NC score	0.918168 (rank : 5)	θ value	6.56568e-51 (rank : 22)
Query Neighborhood Hits	303	Target Neighborhood Hits	142	Shared Neighborhood Hits	108
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.916968 (rank : 6)	θ value	4.54686e-52 (rank : 21)
Query Neighborhood Hits	303	Target Neighborhood Hits	163	Shared Neighborhood Hits	113
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.871849 (rank : 7)	θ value	9.81109e-47 (rank : 26)
Query Neighborhood Hits	303	Target Neighborhood Hits	426	Shared Neighborhood Hits	228
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.862901 (rank : 8)	θ value	4.40402e-47 (rank : 23)
Query Neighborhood Hits	303	Target Neighborhood Hits	471	Shared Neighborhood Hits	226
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN1_MOUSE
NC score	0.742747 (rank : 9)	θ value	2.26182e-43 (rank : 45)
Query Neighborhood Hits	303	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN2_MOUSE
NC score	0.742719 (rank : 10)	θ value	1.56636e-44 (rank : 36)
Query Neighborhood Hits	303	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN18_HUMAN
NC score	0.742601 (rank : 11)	θ value	3.48949e-44 (rank : 39)
Query Neighborhood Hits	303	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN1_HUMAN
NC score	0.742444 (rank : 12)	θ value	7.77379e-44 (rank : 41)
Query Neighborhood Hits	303	Target Neighborhood Hits	84	Shared Neighborhood Hits	66
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN2_HUMAN
NC score	0.742438 (rank : 13)	θ value	4.55743e-44 (rank : 40)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	65
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_MOUSE
NC score	0.740833 (rank : 14)	θ value	5.21438e-40 (rank : 63)
Query Neighborhood Hits	303	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN7_MOUSE
NC score	0.736822 (rank : 15)	θ value	2.86122e-38 (rank : 70)
Query Neighborhood Hits	303	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.736017 (rank : 16)	θ value	3.16345e-37 (rank : 73)
Query Neighborhood Hits	303	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_HUMAN
NC score	0.734518 (rank : 17)	θ value	1.62093e-41 (rank : 52)
Query Neighborhood Hits	303	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN22_HUMAN
NC score	0.734283 (rank : 18)	θ value	2.76489e-41 (rank : 55)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN12_MOUSE
NC score	0.734066 (rank : 19)	θ value	1.62093e-41 (rank : 53)
Query Neighborhood Hits	303	Target Neighborhood Hits	123	Shared Neighborhood Hits	71
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRO_HUMAN
NC score	0.729083 (rank : 20)	θ value	6.15952e-41 (rank : 57)
Query Neighborhood Hits	303	Target Neighborhood Hits	139	Shared Neighborhood Hits	74
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPR2_HUMAN
NC score	0.728739 (rank : 21)	θ value	1.16164e-39 (rank : 65)
Query Neighborhood Hits	303	Target Neighborhood Hits	103	Shared Neighborhood Hits	69
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN9_MOUSE
NC score	0.728261 (rank : 22)	θ value	2.67181e-44 (rank : 38)
Query Neighborhood Hits	303	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_HUMAN
NC score	0.728057 (rank : 23)	θ value	1.56636e-44 (rank : 37)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_MOUSE
NC score	0.727969 (rank : 24)	θ value	3.73686e-38 (rank : 71)
Query Neighborhood Hits	303	Target Neighborhood Hits	179	Shared Neighborhood Hits	71
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPR2_MOUSE
NC score	0.727143 (rank : 25)	θ value	2.34062e-40 (rank : 60)
Query Neighborhood Hits	303	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTN5_MOUSE
NC score	0.726455 (rank : 26)	θ value	4.57862e-28 (rank : 89)
Query Neighborhood Hits	303	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.725881 (rank : 27)	θ value	2.05525e-28 (rank : 88)
Query Neighborhood Hits	303	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

CD45_MOUSE
NC score	0.724735 (rank : 28)	θ value	4.88048e-38 (rank : 72)
Query Neighborhood Hits	303	Target Neighborhood Hits	178	Shared Neighborhood Hits	71
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.724248 (rank : 29)	θ value	2.11701e-41 (rank : 54)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	71
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
NC score	0.723862 (rank : 30)	θ value	6.15952e-41 (rank : 56)
Query Neighborhood Hits	303	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.723811 (rank : 31)	θ value	9.50281e-42 (rank : 49)
Query Neighborhood Hits	303	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRR_HUMAN
NC score	0.723433 (rank : 32)	θ value	4.00176e-32 (rank : 83)
Query Neighborhood Hits	303	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRA_MOUSE
NC score	0.723381 (rank : 33)	θ value	7.27602e-42 (rank : 48)
Query Neighborhood Hits	303	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRN_HUMAN
NC score	0.723236 (rank : 34)	θ value	1.16164e-39 (rank : 67)
Query Neighborhood Hits	303	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRR_MOUSE
NC score	0.723160 (rank : 35)	θ value	4.00176e-32 (rank : 84)
Query Neighborhood Hits	303	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRN_MOUSE
NC score	0.720302 (rank : 36)	θ value	2.34062e-40 (rank : 62)
Query Neighborhood Hits	303	Target Neighborhood Hits	240	Shared Neighborhood Hits	76
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

CD45_HUMAN
NC score	0.718991 (rank : 37)	θ value	4.41421e-39 (rank : 68)
Query Neighborhood Hits	303	Target Neighborhood Hits	243	Shared Neighborhood Hits	73
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRJ_MOUSE
NC score	0.709611 (rank : 38)	θ value	8.30557e-46 (rank : 32)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	76
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.706506 (rank : 39)	θ value	3.72821e-46 (rank : 28)
Query Neighborhood Hits	303	Target Neighborhood Hits	207	Shared Neighborhood Hits	78
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRV_MOUSE
NC score	0.699577 (rank : 40)	θ value	6.15952e-41 (rank : 58)
Query Neighborhood Hits	303	Target Neighborhood Hits	179	Shared Neighborhood Hits	71
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN6_HUMAN
NC score	0.697676 (rank : 41)	θ value	4.86918e-46 (rank : 29)
Query Neighborhood Hits	303	Target Neighborhood Hits	234	Shared Neighborhood Hits	71
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.695589 (rank : 42)	θ value	8.30557e-46 (rank : 31)
Query Neighborhood Hits	303	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

E41LB_MOUSE
NC score	0.682511 (rank : 43)	θ value	1.66191e-70 (rank : 16)
Query Neighborhood Hits	303	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L5_HUMAN
NC score	0.681309 (rank : 44)	θ value	6.7473e-72 (rank : 14)
Query Neighborhood Hits	303	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LA_HUMAN
NC score	0.680963 (rank : 45)	θ value	2.47765e-74 (rank : 13)
Query Neighborhood Hits	303	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.680684 (rank : 46)	θ value	1.27248e-70 (rank : 15)
Query Neighborhood Hits	303	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTPRB_HUMAN
NC score	0.680174 (rank : 47)	θ value	1.73182e-43 (rank : 44)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	76
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

E41L3_HUMAN
NC score	0.678999 (rank : 48)	θ value	7.68416e-84 (rank : 6)
Query Neighborhood Hits	303	Target Neighborhood Hits	113	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

PTN11_MOUSE
NC score	0.678846 (rank : 49)	θ value	1.62093e-41 (rank : 51)
Query Neighborhood Hits	303	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.678794 (rank : 50)	θ value	1.62093e-41 (rank : 50)
Query Neighborhood Hits	303	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRK_HUMAN
NC score	0.678430 (rank : 51)	θ value	5.7518e-47 (rank : 24)
Query Neighborhood Hits	303	Target Neighborhood Hits	228	Shared Neighborhood Hits	69
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

FRMD5_MOUSE
NC score	0.678073 (rank : 52)	θ value	2.48917e-58 (rank : 19)
Query Neighborhood Hits	303	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L1_MOUSE
NC score	0.677364 (rank : 53)	θ value	4.35321e-87 (rank : 4)
Query Neighborhood Hits	303	Target Neighborhood Hits	106	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41LB_HUMAN
NC score	0.677141 (rank : 54)	θ value	1.83746e-69 (rank : 18)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

41_HUMAN
NC score	0.676997 (rank : 55)	θ value	2.47191e-82 (rank : 8)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

PTPRK_MOUSE
NC score	0.676768 (rank : 56)	θ value	5.7518e-47 (rank : 25)
Query Neighborhood Hits	303	Target Neighborhood Hits	223	Shared Neighborhood Hits	67
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

FRMD5_HUMAN
NC score	0.676529 (rank : 57)	θ value	4.24587e-58 (rank : 20)
Query Neighborhood Hits	303	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

41_MOUSE
NC score	0.675060 (rank : 58)	θ value	1.35638e-80 (rank : 10)
Query Neighborhood Hits	303	Target Neighborhood Hits	184	Shared Neighborhood Hits	55
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L1_HUMAN
NC score	0.673892 (rank : 59)	θ value	8.77142e-88 (rank : 3)
Query Neighborhood Hits	303	Target Neighborhood Hits	180	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

PTPRT_MOUSE
NC score	0.672955 (rank : 60)	θ value	1.01529e-43 (rank : 43)
Query Neighborhood Hits	303	Target Neighborhood Hits	219	Shared Neighborhood Hits	68
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.672954 (rank : 61)	θ value	1.01529e-43 (rank : 42)
Query Neighborhood Hits	303	Target Neighborhood Hits	217	Shared Neighborhood Hits	68
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

E41L3_MOUSE
NC score	0.669073 (rank : 62)	θ value	2.23575e-83 (rank : 7)
Query Neighborhood Hits	303	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.667593 (rank : 63)	θ value	2.02215e-84 (rank : 5)
Query Neighborhood Hits	303	Target Neighborhood Hits	287	Shared Neighborhood Hits	55
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PTPRU_HUMAN
NC score	0.666177 (rank : 64)	θ value	1.28434e-38 (rank : 69)
Query Neighborhood Hits	303	Target Neighborhood Hits	237	Shared Neighborhood Hits	70
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_MOUSE
NC score	0.662578 (rank : 65)	θ value	2.50074e-42 (rank : 46)
Query Neighborhood Hits	303	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.661001 (rank : 66)	θ value	3.26607e-42 (rank : 47)
Query Neighborhood Hits	303	Target Neighborhood Hits	244	Shared Neighborhood Hits	69
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRZ_HUMAN
NC score	0.654240 (rank : 67)	θ value	6.81017e-40 (rank : 64)
Query Neighborhood Hits	303	Target Neighborhood Hits	255	Shared Neighborhood Hits	74
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.653356 (rank : 68)	θ value	2.34062e-40 (rank : 61)
Query Neighborhood Hits	303	Target Neighborhood Hits	231	Shared Neighborhood Hits	68
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
NC score	0.651325 (rank : 69)	θ value	1.16164e-39 (rank : 66)
Query Neighborhood Hits	303	Target Neighborhood Hits	260	Shared Neighborhood Hits	72
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

E41L2_MOUSE
NC score	0.650264 (rank : 70)	θ value	4.66183e-81 (rank : 9)
Query Neighborhood Hits	303	Target Neighborhood Hits	459	Shared Neighborhood Hits	59
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PTN23_HUMAN
NC score	0.637938 (rank : 71)	θ value	1.37539e-32 (rank : 77)
Query Neighborhood Hits	303	Target Neighborhood Hits	646	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
NC score	0.637869 (rank : 72)	θ value	1.16434e-31 (rank : 85)
Query Neighborhood Hits	303	Target Neighborhood Hits	726	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MYLIP_MOUSE
NC score	0.615641 (rank : 73)	θ value	4.42448e-31 (rank : 86)
Query Neighborhood Hits	303	Target Neighborhood Hits	139	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.603077 (rank : 74)	θ value	2.19584e-30 (rank : 87)
Query Neighborhood Hits	303	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_HUMAN
NC score	0.564782 (rank : 75)	θ value	3.51386e-20 (rank : 90)
Query Neighborhood Hits	303	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FARP1_HUMAN
NC score	0.564268 (rank : 76)	θ value	8.24801e-70 (rank : 17)
Query Neighborhood Hits	303	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRM4B_MOUSE
NC score	0.563483 (rank : 77)	θ value	4.58923e-20 (rank : 91)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_HUMAN
NC score	0.558314 (rank : 78)	θ value	3.88503e-19 (rank : 93)
Query Neighborhood Hits	303	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
NC score	0.557767 (rank : 79)	θ value	2.97466e-19 (rank : 92)
Query Neighborhood Hits	303	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MERL_MOUSE
NC score	0.557131 (rank : 80)	θ value	3.06405e-32 (rank : 82)
Query Neighborhood Hits	303	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.556670 (rank : 81)	θ value	2.34606e-32 (rank : 79)
Query Neighborhood Hits	303	Target Neighborhood Hits	532	Shared Neighborhood Hits	57
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP2_HUMAN
NC score	0.549199 (rank : 82)	θ value	3.45727e-76 (rank : 11)
Query Neighborhood Hits	303	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.543994 (rank : 83)	θ value	4.51533e-76 (rank : 12)
Query Neighborhood Hits	303	Target Neighborhood Hits	209	Shared Neighborhood Hits	50
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTPRS_HUMAN
NC score	0.527996 (rank : 84)	θ value	1.28137e-46 (rank : 27)
Query Neighborhood Hits	303	Target Neighborhood Hits	472	Shared Neighborhood Hits	75
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

EZRI_HUMAN
NC score	0.527427 (rank : 85)	θ value	3.06405e-32 (rank : 81)
Query Neighborhood Hits	303	Target Neighborhood Hits	663	Shared Neighborhood Hits	51
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.524148 (rank : 86)	θ value	1.37539e-32 (rank : 76)
Query Neighborhood Hits	303	Target Neighborhood Hits	693	Shared Neighborhood Hits	52
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTPRD_HUMAN
NC score	0.518143 (rank : 87)	θ value	6.35935e-46 (rank : 30)
Query Neighborhood Hits	303	Target Neighborhood Hits	485	Shared Neighborhood Hits	77
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.515355 (rank : 88)	θ value	9.18288e-45 (rank : 35)
Query Neighborhood Hits	303	Target Neighborhood Hits	489	Shared Neighborhood Hits	75
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

RADI_HUMAN
NC score	0.514738 (rank : 89)	θ value	3.61944e-33 (rank : 74)
Query Neighborhood Hits	303	Target Neighborhood Hits	741	Shared Neighborhood Hits	54
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.511816 (rank : 90)	θ value	3.61944e-33 (rank : 75)
Query Neighborhood Hits	303	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

PTPRD_MOUSE
NC score	0.509225 (rank : 91)	θ value	1.79215e-40 (rank : 59)
Query Neighborhood Hits	303	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FRMD6_MOUSE
NC score	0.499076 (rank : 92)	θ value	4.16044e-13 (rank : 95)
Query Neighborhood Hits	303	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.493270 (rank : 93)	θ value	1.86753e-13 (rank : 94)
Query Neighborhood Hits	303	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

MOES_HUMAN
NC score	0.481874 (rank : 94)	θ value	2.34606e-32 (rank : 80)
Query Neighborhood Hits	303	Target Neighborhood Hits	892	Shared Neighborhood Hits	53
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD1_HUMAN
NC score	0.481335 (rank : 95)	θ value	6.21693e-09 (rank : 102)
Query Neighborhood Hits	303	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

MOES_MOUSE
NC score	0.476942 (rank : 96)	θ value	1.79631e-32 (rank : 78)
Query Neighborhood Hits	303	Target Neighborhood Hits	923	Shared Neighborhood Hits	57
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TLN1_HUMAN
NC score	0.314251 (rank : 97)	θ value	2.98157e-11 (rank : 96)
Query Neighborhood Hits	303	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.311853 (rank : 98)	θ value	2.98157e-11 (rank : 97)
Query Neighborhood Hits	303	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.310671 (rank : 99)	θ value	2.13673e-09 (rank : 99)
Query Neighborhood Hits	303	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.307406 (rank : 100)	θ value	1.25267e-09 (rank : 98)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

DUS23_MOUSE
NC score	0.233035 (rank : 101)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	303	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

DUS23_HUMAN
NC score	0.223961 (rank : 102)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	303	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

PDZ11_MOUSE
NC score	0.214755 (rank : 103)	θ value	0.000158464 (rank : 118)
Query Neighborhood Hits	303	Target Neighborhood Hits	154	Shared Neighborhood Hits	110
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_HUMAN
NC score	0.213400 (rank : 104)	θ value	0.00020696 (rank : 121)
Query Neighborhood Hits	303	Target Neighborhood Hits	160	Shared Neighborhood Hits	112
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LIN7C_HUMAN
NC score	0.212374 (rank : 105)	θ value	2.79066e-09 (rank : 100)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.212374 (rank : 106)	θ value	2.79066e-09 (rank : 101)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SNTB2_HUMAN
NC score	0.209782 (rank : 107)	θ value	1.38499e-08 (rank : 103)
Query Neighborhood Hits	303	Target Neighborhood Hits	180	Shared Neighborhood Hits	117
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
NC score	0.209752 (rank : 108)	θ value	1.80886e-08 (rank : 104)
Query Neighborhood Hits	303	Target Neighborhood Hits	181	Shared Neighborhood Hits	118
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LIN7B_HUMAN
NC score	0.209225 (rank : 109)	θ value	1.69304e-06 (rank : 109)
Query Neighborhood Hits	303	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.209101 (rank : 110)	θ value	1.69304e-06 (rank : 110)
Query Neighborhood Hits	303	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_HUMAN
NC score	0.208560 (rank : 111)	θ value	1.87187e-05 (rank : 115)
Query Neighborhood Hits	303	Target Neighborhood Hits	193	Shared Neighborhood Hits	118
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.208528 (rank : 112)	θ value	1.87187e-05 (rank : 116)
Query Neighborhood Hits	303	Target Neighborhood Hits	193	Shared Neighborhood Hits	118
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

SNTB1_HUMAN
NC score	0.200778 (rank : 113)	θ value	4.45536e-07 (rank : 105)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	109
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTA1_MOUSE
NC score	0.200701 (rank : 114)	θ value	1.29631e-06 (rank : 108)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	109
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTB1_MOUSE
NC score	0.200650 (rank : 115)	θ value	4.45536e-07 (rank : 106)
Query Neighborhood Hits	303	Target Neighborhood Hits	160	Shared Neighborhood Hits	109
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTA1_HUMAN
NC score	0.200436 (rank : 116)	θ value	9.92553e-07 (rank : 107)
Query Neighborhood Hits	303	Target Neighborhood Hits	186	Shared Neighborhood Hits	109
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

GOPC_MOUSE
NC score	0.194311 (rank : 117)	θ value	1.09739e-05 (rank : 114)
Query Neighborhood Hits	303	Target Neighborhood Hits	323	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PDZD7_HUMAN
NC score	0.192541 (rank : 118)	θ value	0.00102713 (rank : 129)
Query Neighborhood Hits	303	Target Neighborhood Hits	181	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

GOPC_HUMAN
NC score	0.192312 (rank : 119)	θ value	1.09739e-05 (rank : 113)
Query Neighborhood Hits	303	Target Neighborhood Hits	377	Shared Neighborhood Hits	120
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SYJ2B_HUMAN
NC score	0.189871 (rank : 120)	θ value	0.0431538 (rank : 170)
Query Neighborhood Hits	303	Target Neighborhood Hits	162	Shared Neighborhood Hits	109
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SNTG2_MOUSE
NC score	0.188703 (rank : 121)	θ value	3.19293e-05 (rank : 117)
Query Neighborhood Hits	303	Target Neighborhood Hits	176	Shared Neighborhood Hits	114
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG2_HUMAN
NC score	0.186991 (rank : 122)	θ value	0.000786445 (rank : 128)
Query Neighborhood Hits	303	Target Neighborhood Hits	191	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG1_MOUSE
NC score	0.186539 (rank : 123)	θ value	0.000602161 (rank : 125)
Query Neighborhood Hits	303	Target Neighborhood Hits	179	Shared Neighborhood Hits	115
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.185971 (rank : 124)	θ value	0.000786445 (rank : 127)
Query Neighborhood Hits	303	Target Neighborhood Hits	181	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

WHRN_MOUSE
NC score	0.182647 (rank : 125)	θ value	0.000270298 (rank : 122)
Query Neighborhood Hits	303	Target Neighborhood Hits	412	Shared Neighborhood Hits	128
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
NC score	0.179858 (rank : 126)	θ value	0.00175202 (rank : 139)
Query Neighborhood Hits	303	Target Neighborhood Hits	325	Shared Neighborhood Hits	122
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

TX1B3_MOUSE
NC score	0.173552 (rank : 127)	θ value	0.00298849 (rank : 144)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	106
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

TX1B3_HUMAN
NC score	0.173458 (rank : 128)	θ value	0.00298849 (rank : 143)
Query Neighborhood Hits	303	Target Neighborhood Hits	161	Shared Neighborhood Hits	106
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

USH1C_HUMAN
NC score	0.171885 (rank : 129)	θ value	0.0563607 (rank : 171)
Query Neighborhood Hits	303	Target Neighborhood Hits	327	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

MAGI2_HUMAN
NC score	0.169998 (rank : 130)	θ value	2.88788e-06 (rank : 111)
Query Neighborhood Hits	303	Target Neighborhood Hits	373	Shared Neighborhood Hits	126
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
NC score	0.169928 (rank : 131)	θ value	3.77169e-06 (rank : 112)
Query Neighborhood Hits	303	Target Neighborhood Hits	370	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI1_MOUSE
NC score	0.166323 (rank : 132)	θ value	0.000786445 (rank : 126)
Query Neighborhood Hits	303	Target Neighborhood Hits	403	Shared Neighborhood Hits	126
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.165871 (rank : 133)	θ value	0.00175202 (rank : 135)
Query Neighborhood Hits	303	Target Neighborhood Hits	388	Shared Neighborhood Hits	124
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

USH1C_MOUSE
NC score	0.163751 (rank : 134)	θ value	0.0563607 (rank : 172)
Query Neighborhood Hits	303	Target Neighborhood Hits	557	Shared Neighborhood Hits	132
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

NHERF_MOUSE
NC score	0.162599 (rank : 135)	θ value	0.0330416 (rank : 166)
Query Neighborhood Hits	303	Target Neighborhood Hits	195	Shared Neighborhood Hits	118
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.162233 (rank : 136)	θ value	0.00228821 (rank : 140)
Query Neighborhood Hits	303	Target Neighborhood Hits	197	Shared Neighborhood Hits	115
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

MPDZ_MOUSE
NC score	0.161878 (rank : 137)	θ value	0.00175202 (rank : 136)
Query Neighborhood Hits	303	Target Neighborhood Hits	298	Shared Neighborhood Hits	121
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NHERF_HUMAN
NC score	0.161254 (rank : 138)	θ value	0.0148317 (rank : 154)
Query Neighborhood Hits	303	Target Neighborhood Hits	190	Shared Neighborhood Hits	118
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_MOUSE
NC score	0.160267 (rank : 139)	θ value	0.00134147 (rank : 132)
Query Neighborhood Hits	303	Target Neighborhood Hits	191	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHRF2_MOUSE
NC score	0.159692 (rank : 140)	θ value	0.00175202 (rank : 137)
Query Neighborhood Hits	303	Target Neighborhood Hits	194	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

MPDZ_HUMAN
NC score	0.158726 (rank : 141)	θ value	0.00665767 (rank : 149)
Query Neighborhood Hits	303	Target Neighborhood Hits	261	Shared Neighborhood Hits	117
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

IL16_HUMAN
NC score	0.157552 (rank : 142)	θ value	1.06291 (rank : 221)
Query Neighborhood Hits	303	Target Neighborhood Hits	207	Shared Neighborhood Hits	106
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZD1_HUMAN
NC score	0.155076 (rank : 143)	θ value	0.00869519 (rank : 152)
Query Neighborhood Hits	303	Target Neighborhood Hits	190	Shared Neighborhood Hits	111
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

INADL_MOUSE
NC score	0.154966 (rank : 144)	θ value	1.81305 (rank : 237)
Query Neighborhood Hits	303	Target Neighborhood Hits	290	Shared Neighborhood Hits	122
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

GRIP2_HUMAN
NC score	0.154642 (rank : 145)	θ value	0.163984 (rank : 185)
Query Neighborhood Hits	303	Target Neighborhood Hits	256	Shared Neighborhood Hits	124
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

IL16_MOUSE
NC score	0.154477 (rank : 146)	θ value	0.813845 (rank : 215)
Query Neighborhood Hits	303	Target Neighborhood Hits	189	Shared Neighborhood Hits	100
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

INADL_HUMAN
NC score	0.153319 (rank : 147)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	303	Target Neighborhood Hits	260	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

GRIP1_MOUSE
NC score	0.151669 (rank : 148)	θ value	0.0961366 (rank : 178)
Query Neighborhood Hits	303	Target Neighborhood Hits	241	Shared Neighborhood Hits	120
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_HUMAN
NC score	0.151505 (rank : 149)	θ value	0.0961366 (rank : 177)
Query Neighborhood Hits	303	Target Neighborhood Hits	231	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

DLG4_MOUSE
NC score	0.150741 (rank : 150)	θ value	0.000461057 (rank : 124)
Query Neighborhood Hits	303	Target Neighborhood Hits	282	Shared Neighborhood Hits	114
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.150584 (rank : 151)	θ value	0.000461057 (rank : 123)
Query Neighborhood Hits	303	Target Neighborhood Hits	286	Shared Neighborhood Hits	114
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG3_MOUSE
NC score	0.147594 (rank : 152)	θ value	0.00390308 (rank : 147)
Query Neighborhood Hits	303	Target Neighborhood Hits	274	Shared Neighborhood Hits	113
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_HUMAN
NC score	0.147592 (rank : 153)	θ value	0.00665767 (rank : 148)
Query Neighborhood Hits	303	Target Neighborhood Hits	290	Shared Neighborhood Hits	119
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG3_HUMAN
NC score	0.147475 (rank : 154)	θ value	0.00390308 (rank : 146)
Query Neighborhood Hits	303	Target Neighborhood Hits	269	Shared Neighborhood Hits	114
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG2_MOUSE
NC score	0.147255 (rank : 155)	θ value	0.00134147 (rank : 131)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	110
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
NC score	0.146829 (rank : 156)	θ value	0.00134147 (rank : 130)
Query Neighborhood Hits	303	Target Neighborhood Hits	279	Shared Neighborhood Hits	112
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PAR3L_HUMAN
NC score	0.146577 (rank : 157)	θ value	0.0431538 (rank : 168)
Query Neighborhood Hits	303	Target Neighborhood Hits	297	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

DLG1_MOUSE
NC score	0.144209 (rank : 158)	θ value	0.00390308 (rank : 145)
Query Neighborhood Hits	303	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

ZO3_MOUSE
NC score	0.143792 (rank : 159)	θ value	0.00228821 (rank : 142)
Query Neighborhood Hits	303	Target Neighborhood Hits	224	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZD2_HUMAN
NC score	0.141543 (rank : 160)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	303	Target Neighborhood Hits	772	Shared Neighborhood Hits	136
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LNX2_MOUSE
NC score	0.141198 (rank : 161)	θ value	0.0330416 (rank : 164)
Query Neighborhood Hits	303	Target Neighborhood Hits	407	Shared Neighborhood Hits	121
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

ZO3_HUMAN
NC score	0.139539 (rank : 162)	θ value	0.0148317 (rank : 155)
Query Neighborhood Hits	303	Target Neighborhood Hits	219	Shared Neighborhood Hits	111
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LNX2_HUMAN
NC score	0.139482 (rank : 163)	θ value	0.0193708 (rank : 156)
Query Neighborhood Hits	303	Target Neighborhood Hits	389	Shared Neighborhood Hits	120
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

ZO2_HUMAN
NC score	0.138427 (rank : 164)	θ value	0.00869519 (rank : 153)
Query Neighborhood Hits	303	Target Neighborhood Hits	289	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PARD3_HUMAN
NC score	0.137218 (rank : 165)	θ value	3.0926 (rank : 256)
Query Neighborhood Hits	303	Target Neighborhood Hits	312	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

RHPN1_HUMAN
NC score	0.135781 (rank : 166)	θ value	0.0252991 (rank : 162)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
NC score	0.135715 (rank : 167)	θ value	0.125558 (rank : 183)
Query Neighborhood Hits	303	Target Neighborhood Hits	154	Shared Neighborhood Hits	104
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDZD3_HUMAN
NC score	0.135577 (rank : 168)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	303	Target Neighborhood Hits	180	Shared Neighborhood Hits	108
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PARD3_MOUSE
NC score	0.135207 (rank : 169)	θ value	5.27518 (rank : 277)
Query Neighborhood Hits	303	Target Neighborhood Hits	290	Shared Neighborhood Hits	106
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

ZO2_MOUSE
NC score	0.134653 (rank : 170)	θ value	0.00665767 (rank : 151)
Query Neighborhood Hits	303	Target Neighborhood Hits	296	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

PDLI2_MOUSE
NC score	0.133062 (rank : 171)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	303	Target Neighborhood Hits	220	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

SYNP2_MOUSE
NC score	0.131281 (rank : 172)	θ value	0.00134147 (rank : 133)
Query Neighborhood Hits	303	Target Neighborhood Hits	252	Shared Neighborhood Hits	103
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

GRASP_HUMAN
NC score	0.129942 (rank : 173)	θ value	0.0330416 (rank : 163)
Query Neighborhood Hits	303	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LNX1_MOUSE
NC score	0.128832 (rank : 174)	θ value	5.27518 (rank : 275)
Query Neighborhood Hits	303	Target Neighborhood Hits	377	Shared Neighborhood Hits	113
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDLI2_HUMAN
NC score	0.127730 (rank : 175)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	303	Target Neighborhood Hits	245	Shared Neighborhood Hits	110
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

GRASP_MOUSE
NC score	0.127629 (rank : 176)	θ value	0.0736092 (rank : 173)
Query Neighborhood Hits	303	Target Neighborhood Hits	131	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

ZO1_HUMAN
NC score	0.127553 (rank : 177)	θ value	0.163984 (rank : 186)
Query Neighborhood Hits	303	Target Neighborhood Hits	474	Shared Neighborhood Hits	125
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
NC score	0.127382 (rank : 178)	θ value	0.21417 (rank : 190)
Query Neighborhood Hits	303	Target Neighborhood Hits	453	Shared Neighborhood Hits	123
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SYP2L_HUMAN
NC score	0.127348 (rank : 179)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	303	Target Neighborhood Hits	400	Shared Neighborhood Hits	108
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDZD3_MOUSE
NC score	0.126563 (rank : 180)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	303	Target Neighborhood Hits	171	Shared Neighborhood Hits	111
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PZRN4_HUMAN
NC score	0.125284 (rank : 181)	θ value	0.279714 (rank : 192)
Query Neighborhood Hits	303	Target Neighborhood Hits	438	Shared Neighborhood Hits	99
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

LNX1_HUMAN
NC score	0.124572 (rank : 182)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	303	Target Neighborhood Hits	379	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PZRN3_HUMAN
NC score	0.123261 (rank : 183)	θ value	0.0193708 (rank : 157)
Query Neighborhood Hits	303	Target Neighborhood Hits	461	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
NC score	0.122148 (rank : 184)	θ value	0.0431538 (rank : 169)
Query Neighborhood Hits	303	Target Neighborhood Hits	447	Shared Neighborhood Hits	101
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

CC14B_MOUSE
NC score	0.119949 (rank : 185)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	303	Target Neighborhood Hits	103	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PDLI1_MOUSE
NC score	0.118445 (rank : 186)	θ value	0.00175202 (rank : 138)
Query Neighborhood Hits	303	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI3_HUMAN
NC score	0.118180 (rank : 187)	θ value	0.0252991 (rank : 161)
Query Neighborhood Hits	303	Target Neighborhood Hits	199	Shared Neighborhood Hits	99
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

CC14B_HUMAN
NC score	0.117562 (rank : 188)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	303	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

SYNP2_HUMAN
NC score	0.117198 (rank : 189)	θ value	0.00228821 (rank : 141)
Query Neighborhood Hits	303	Target Neighborhood Hits	323	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TP4A1_HUMAN
NC score	0.116130 (rank : 190)	θ value	0.279714 (rank : 194)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.116130 (rank : 191)	θ value	0.279714 (rank : 195)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

PDLI3_MOUSE
NC score	0.115595 (rank : 192)	θ value	0.0330416 (rank : 167)
Query Neighborhood Hits	303	Target Neighborhood Hits	197	Shared Neighborhood Hits	95
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

APXL_HUMAN
NC score	0.113159 (rank : 193)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	303	Target Neighborhood Hits	553	Shared Neighborhood Hits	92
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PDLI1_HUMAN
NC score	0.112634 (rank : 194)	θ value	0.00665767 (rank : 150)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	86
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

FINC_HUMAN
NC score	0.107688 (rank : 195)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	303	Target Neighborhood Hits	302	Shared Neighborhood Hits	25
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

PDLI4_MOUSE
NC score	0.107535 (rank : 196)	θ value	0.365318 (rank : 199)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_HUMAN
NC score	0.107043 (rank : 197)	θ value	0.365318 (rank : 198)
Query Neighborhood Hits	303	Target Neighborhood Hits	245	Shared Neighborhood Hits	93
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

FINC_MOUSE
NC score	0.106800 (rank : 198)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	303	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LAP4_MOUSE
NC score	0.106789 (rank : 199)	θ value	0.00175202 (rank : 134)
Query Neighborhood Hits	303	Target Neighborhood Hits	590	Shared Neighborhood Hits	123
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

CC14A_MOUSE
NC score	0.106752 (rank : 200)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	303	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

LAP4_HUMAN
NC score	0.105490 (rank : 201)	θ value	0.0252991 (rank : 160)
Query Neighborhood Hits	303	Target Neighborhood Hits	608	Shared Neighborhood Hits	124
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

CC14A_HUMAN
NC score	0.104259 (rank : 202)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	303	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

SYP2L_MOUSE
NC score	0.103139 (rank : 203)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	303	Target Neighborhood Hits	289	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TP4A2_HUMAN
NC score	0.102677 (rank : 204)	θ value	0.0193708 (rank : 158)
Query Neighborhood Hits	303	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.102677 (rank : 205)	θ value	0.0193708 (rank : 159)
Query Neighborhood Hits	303	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

K1849_MOUSE
NC score	0.099210 (rank : 206)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	303	Target Neighborhood Hits	335	Shared Neighborhood Hits	100
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ARHGB_HUMAN
NC score	0.098248 (rank : 207)	θ value	0.279714 (rank : 191)
Query Neighborhood Hits	303	Target Neighborhood Hits	375	Shared Neighborhood Hits	115
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

K1849_HUMAN
NC score	0.096777 (rank : 208)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	303	Target Neighborhood Hits	220	Shared Neighborhood Hits	94
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

FNDC3_HUMAN
NC score	0.096634 (rank : 209)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	303	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

RPGF6_HUMAN
NC score	0.096541 (rank : 210)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	303	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

LDB3_MOUSE
NC score	0.096152 (rank : 211)	θ value	0.00020696 (rank : 120)
Query Neighborhood Hits	303	Target Neighborhood Hits	510	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

TP4A3_HUMAN
NC score	0.095450 (rank : 212)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	303	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

PSCBP_MOUSE
NC score	0.095272 (rank : 213)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	303	Target Neighborhood Hits	118	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

LDB3_HUMAN
NC score	0.094208 (rank : 214)	θ value	0.00020696 (rank : 119)
Query Neighborhood Hits	303	Target Neighborhood Hits	497	Shared Neighborhood Hits	103
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

AFAD_HUMAN
NC score	0.093063 (rank : 215)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	303	Target Neighborhood Hits	689	Shared Neighborhood Hits	101
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

FNDC3_MOUSE
NC score	0.090167 (rank : 216)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	303	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

STXB4_HUMAN
NC score	0.087198 (rank : 217)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	303	Target Neighborhood Hits	616	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PSCBP_HUMAN
NC score	0.086971 (rank : 218)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	303	Target Neighborhood Hits	123	Shared Neighborhood Hits	85
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

DLG5_HUMAN
NC score	0.086592 (rank : 219)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	303	Target Neighborhood Hits	1088	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

TP4A3_MOUSE
NC score	0.085730 (rank : 220)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	303	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

ARHGC_HUMAN
NC score	0.084240 (rank : 221)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	303	Target Neighborhood Hits	351	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.083309 (rank : 222)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	303	Target Neighborhood Hits	344	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SDCB1_MOUSE
NC score	0.082716 (rank : 223)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	303	Target Neighborhood Hits	144	Shared Neighborhood Hits	96
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

PICK1_HUMAN
NC score	0.082400 (rank : 224)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	303	Target Neighborhood Hits	132	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

NEB2_HUMAN
NC score	0.080847 (rank : 225)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	303	Target Neighborhood Hits	883	Shared Neighborhood Hits	89
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RGS12_HUMAN
NC score	0.080831 (rank : 226)	θ value	0.279714 (rank : 193)
Query Neighborhood Hits	303	Target Neighborhood Hits	333	Shared Neighborhood Hits	105
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

PICK1_MOUSE
NC score	0.080651 (rank : 227)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	303	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

DCC_HUMAN
NC score	0.079672 (rank : 228)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	303	Target Neighborhood Hits	583	Shared Neighborhood Hits	30
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

MPP4_HUMAN
NC score	0.079632 (rank : 229)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	303	Target Neighborhood Hits	205	Shared Neighborhood Hits	85
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NEB1_HUMAN
NC score	0.078905 (rank : 230)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	303	Target Neighborhood Hits	829	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SDCB1_HUMAN
NC score	0.078526 (rank : 231)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	303	Target Neighborhood Hits	150	Shared Neighborhood Hits	96
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

NEB2_MOUSE
NC score	0.078460 (rank : 232)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	303	Target Neighborhood Hits	889	Shared Neighborhood Hits	90
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

STXB4_MOUSE
NC score	0.078441 (rank : 233)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	303	Target Neighborhood Hits	629	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DCC_MOUSE
NC score	0.077683 (rank : 234)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	303	Target Neighborhood Hits	896	Shared Neighborhood Hits	46
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

NEO1_MOUSE
NC score	0.077629 (rank : 235)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	303	Target Neighborhood Hits	523	Shared Neighborhood Hits	26
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

PTEN_HUMAN
NC score	0.077063 (rank : 236)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	303	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.077062 (rank : 237)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	303	Target Neighborhood Hits	73	Shared Neighborhood Hits	41
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

PDZK4_MOUSE
NC score	0.076837 (rank : 238)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_HUMAN
NC score	0.075811 (rank : 239)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDLI7_HUMAN
NC score	0.075299 (rank : 240)	θ value	0.0736092 (rank : 176)
Query Neighborhood Hits	303	Target Neighborhood Hits	547	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

NEO1_HUMAN
NC score	0.075209 (rank : 241)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	303	Target Neighborhood Hits	530	Shared Neighborhood Hits	26
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

PDLI7_MOUSE
NC score	0.074095 (rank : 242)	θ value	0.0961366 (rank : 180)
Query Neighborhood Hits	303	Target Neighborhood Hits	279	Shared Neighborhood Hits	85
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

TENN_MOUSE
NC score	0.074088 (rank : 243)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	303	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

RPGF2_HUMAN
NC score	0.073719 (rank : 244)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

MAMC2_MOUSE
NC score	0.073658 (rank : 245)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	303	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

PDLI5_MOUSE
NC score	0.073249 (rank : 246)	θ value	2.36792 (rank : 247)
Query Neighborhood Hits	303	Target Neighborhood Hits	287	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

MPP5_MOUSE
NC score	0.072965 (rank : 247)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	303	Target Neighborhood Hits	226	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP5_HUMAN
NC score	0.072844 (rank : 248)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	303	Target Neighborhood Hits	231	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

PAR6G_MOUSE
NC score	0.072191 (rank : 249)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	303	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

NOS1_HUMAN
NC score	0.072166 (rank : 250)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	303	Target Neighborhood Hits	218	Shared Neighborhood Hits	93
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PAR6G_HUMAN
NC score	0.072091 (rank : 251)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	303	Target Neighborhood Hits	159	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PDLI5_HUMAN
NC score	0.071890 (rank : 252)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	303	Target Neighborhood Hits	322	Shared Neighborhood Hits	97
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SDCB2_HUMAN
NC score	0.071337 (rank : 253)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	303	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

COCA1_MOUSE
NC score	0.070853 (rank : 254)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	303	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MPP3_MOUSE
NC score	0.070718 (rank : 255)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	77
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MAMC2_HUMAN
NC score	0.070665 (rank : 256)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	303	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

CDKN3_HUMAN
NC score	0.069935 (rank : 257)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	303	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

MPP3_HUMAN
NC score	0.069917 (rank : 258)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	303	Target Neighborhood Hits	171	Shared Neighborhood Hits	77
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

PAR6B_HUMAN
NC score	0.069522 (rank : 259)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	303	Target Neighborhood Hits	126	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

APBA1_HUMAN
NC score	0.069393 (rank : 260)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	303	Target Neighborhood Hits	325	Shared Neighborhood Hits	90
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

COCA1_HUMAN
NC score	0.069344 (rank : 261)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	303	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PAR6B_MOUSE
NC score	0.068999 (rank : 262)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	303	Target Neighborhood Hits	128	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

MPP4_MOUSE
NC score	0.068770 (rank : 263)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

USH2A_HUMAN
NC score	0.067439 (rank : 264)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	303	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

DVL1_HUMAN
NC score	0.067056 (rank : 265)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	82
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SDK2_MOUSE
NC score	0.066999 (rank : 266)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	303	Target Neighborhood Hits	480	Shared Neighborhood Hits	23
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

DVL3_HUMAN
NC score	0.066614 (rank : 267)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	303	Target Neighborhood Hits	194	Shared Neighborhood Hits	78
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.066143 (rank : 268)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	78
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SDCB2_MOUSE
NC score	0.066126 (rank : 269)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	303	Target Neighborhood Hits	118	Shared Neighborhood Hits	76
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

DVL1_MOUSE
NC score	0.065347 (rank : 270)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	79
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

APBA2_HUMAN
NC score	0.064982 (rank : 271)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	303	Target Neighborhood Hits	220	Shared Neighborhood Hits	87
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

SDK1_MOUSE
NC score	0.064581 (rank : 272)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	303	Target Neighborhood Hits	495	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.064475 (rank : 273)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	303	Target Neighborhood Hits	495	Shared Neighborhood Hits	25
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

APBA2_MOUSE
NC score	0.064460 (rank : 274)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	303	Target Neighborhood Hits	219	Shared Neighborhood Hits	85
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

USH2A_MOUSE
NC score	0.064448 (rank : 275)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	303	Target Neighborhood Hits	626	Shared Neighborhood Hits	25
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

APBA3_HUMAN
NC score	0.063716 (rank : 276)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	303	Target Neighborhood Hits	201	Shared Neighborhood Hits	77
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SDK1_HUMAN
NC score	0.063585 (rank : 277)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	303	Target Neighborhood Hits	511	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

DVL2_MOUSE
NC score	0.063311 (rank : 278)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.063048 (rank : 279)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	303	Target Neighborhood Hits	223	Shared Neighborhood Hits	80
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

TENN_HUMAN
NC score	0.063032 (rank : 280)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	303	Target Neighborhood Hits	453	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

DVL1L_HUMAN
NC score	0.062737 (rank : 281)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

EM55_HUMAN
NC score	0.062695 (rank : 282)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	303	Target Neighborhood Hits	228	Shared Neighborhood Hits	77
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

KRIT1_HUMAN
NC score	0.062582 (rank : 283)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PAR6A_MOUSE
NC score	0.062574 (rank : 284)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	303	Target Neighborhood Hits	115	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

APBA3_MOUSE
NC score	0.062481 (rank : 285)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	303	Target Neighborhood Hits	174	Shared Neighborhood Hits	80
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ITB4_HUMAN
NC score	0.062179 (rank : 286)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	303	Target Neighborhood Hits	458	Shared Neighborhood Hits	21
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

RHPN2_MOUSE
NC score	0.062089 (rank : 287)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	303	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

TENR_HUMAN
NC score	0.062053 (rank : 288)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	303	Target Neighborhood Hits	526	Shared Neighborhood Hits	20
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

LRRC7_HUMAN
NC score	0.062038 (rank : 289)	θ value	0.0736092 (rank : 174)
Query Neighborhood Hits	303	Target Neighborhood Hits	423	Shared Neighborhood Hits	95
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

NOS1_MOUSE
NC score	0.061942 (rank : 290)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	303	Target Neighborhood Hits	155	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PAR6A_HUMAN
NC score	0.061883 (rank : 291)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

TENR_MOUSE
NC score	0.061822 (rank : 292)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	303	Target Neighborhood Hits	531	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

LRRC7_MOUSE
NC score	0.061475 (rank : 293)	θ value	0.0736092 (rank : 175)
Query Neighborhood Hits	303	Target Neighborhood Hits	416	Shared Neighborhood Hits	92
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

EM55_MOUSE
NC score	0.060262 (rank : 294)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	303	Target Neighborhood Hits	221	Shared Neighborhood Hits	76
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

TARSH_HUMAN
NC score	0.060231 (rank : 295)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	303	Target Neighborhood Hits	768	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CA106_HUMAN
NC score	0.059176 (rank : 296)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	303	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

L1CAM_MOUSE
NC score	0.058945 (rank : 297)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	303	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

KRIT1_MOUSE
NC score	0.058484 (rank : 298)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

CA106_MOUSE
NC score	0.058423 (rank : 299)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	303	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

L1CAM_HUMAN
NC score	0.058271 (rank : 300)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	303	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NRCAM_MOUSE
NC score	0.058077 (rank : 301)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	303	Target Neighborhood Hits	432	Shared Neighborhood Hits	16
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

RES18_MOUSE
NC score	0.057854 (rank : 302)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	303	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

COEA1_MOUSE
NC score	0.057779 (rank : 303)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	303	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DSCL1_HUMAN
NC score	0.057529 (rank : 304)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	303	Target Neighborhood Hits	589	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DSCAM_HUMAN
NC score	0.057524 (rank : 305)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	303	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

LAP2_HUMAN
NC score	0.056688 (rank : 306)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	303	Target Neighborhood Hits	499	Shared Neighborhood Hits	91
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

NRCAM_HUMAN
NC score	0.056229 (rank : 307)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	303	Target Neighborhood Hits	439	Shared Neighborhood Hits	14
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CNTN5_HUMAN
NC score	0.056140 (rank : 308)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	303	Target Neighborhood Hits	446	Shared Neighborhood Hits	16
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

MDGA1_HUMAN
NC score	0.055676 (rank : 309)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	303	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

SHAN2_HUMAN
NC score	0.055072 (rank : 310)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	303	Target Neighborhood Hits	346	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

CNTN5_MOUSE
NC score	0.054832 (rank : 311)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	303	Target Neighborhood Hits	434	Shared Neighborhood Hits	15
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CO7A1_HUMAN
NC score	0.054680 (rank : 312)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	303	Target Neighborhood Hits	807	Shared Neighborhood Hits	32
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CNTN2_HUMAN
NC score	0.054323 (rank : 313)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	303	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.054187 (rank : 314)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	303	Target Neighborhood Hits	450	Shared Neighborhood Hits	14
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

TENA_HUMAN
NC score	0.053713 (rank : 315)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	303	Target Neighborhood Hits	631	Shared Neighborhood Hits	23
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LAP2_MOUSE
NC score	0.053374 (rank : 316)	θ value	0.813845 (rank : 216)
Query Neighborhood Hits	303	Target Neighborhood Hits	482	Shared Neighborhood Hits	86
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MAMC1_MOUSE
NC score	0.053330 (rank : 317)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	303	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

RIMS1_HUMAN
NC score	0.052773 (rank : 318)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	303	Target Neighborhood Hits	437	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

MYOM1_MOUSE
NC score	0.052492 (rank : 319)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	303	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MAMC1_HUMAN
NC score	0.052369 (rank : 320)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	303	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MPP2_MOUSE
NC score	0.052212 (rank : 321)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	303	Target Neighborhood Hits	189	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP2_HUMAN
NC score	0.051688 (rank : 322)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	303	Target Neighborhood Hits	173	Shared Neighborhood Hits	63
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

PDC6I_MOUSE
NC score	0.051586 (rank : 323)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	303	Target Neighborhood Hits	275	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

COEA1_HUMAN
NC score	0.051498 (rank : 324)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	303	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CNTN1_MOUSE
NC score	0.051469 (rank : 325)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	303	Target Neighborhood Hits	422	Shared Neighborhood Hits	13
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

RHPN2_HUMAN
NC score	0.051244 (rank : 326)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	303	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

NFASC_HUMAN
NC score	0.050790 (rank : 327)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	303	Target Neighborhood Hits	497	Shared Neighborhood Hits	20
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CNTN1_HUMAN
NC score	0.050357 (rank : 328)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	303	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

TENX_HUMAN
NC score	0.038721 (rank : 329)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	303	Target Neighborhood Hits	789	Shared Neighborhood Hits	24
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MYO7A_MOUSE
NC score	0.038079 (rank : 330)	θ value	0.0330416 (rank : 165)
Query Neighborhood Hits	303	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.037831 (rank : 331)	θ value	0.0961366 (rank : 179)
Query Neighborhood Hits	303	Target Neighborhood Hits	209	Shared Neighborhood Hits	27
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SHAN1_HUMAN
NC score	0.035656 (rank : 332)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	303	Target Neighborhood Hits	1041	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TPTE2_HUMAN
NC score	0.034864 (rank : 333)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

DUS11_MOUSE
NC score	0.034368 (rank : 334)	θ value	1.06291 (rank : 220)
Query Neighborhood Hits	303	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

MY18A_HUMAN
NC score	0.026181 (rank : 335)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	303	Target Neighborhood Hits	1929	Shared Neighborhood Hits	105
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MLL3_MOUSE
NC score	0.023127 (rank : 336)	θ value	0.125558 (rank : 182)
Query Neighborhood Hits	303	Target Neighborhood Hits	1399	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.022433 (rank : 337)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	303	Target Neighborhood Hits	1644	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TM131_MOUSE
NC score	0.021671 (rank : 338)	θ value	0.125558 (rank : 184)
Query Neighborhood Hits	303	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

CBP_HUMAN
NC score	0.019966 (rank : 339)	θ value	1.81305 (rank : 235)
Query Neighborhood Hits	303	Target Neighborhood Hits	941	Shared Neighborhood Hits	47
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BSN_HUMAN
NC score	0.019870 (rank : 340)	θ value	5.27518 (rank : 273)
Query Neighborhood Hits	303	Target Neighborhood Hits	1537	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SOS1_HUMAN
NC score	0.018771 (rank : 341)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	303	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SSBP3_HUMAN
NC score	0.017799 (rank : 342)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	303	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.017799 (rank : 343)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	303	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

NCOR1_MOUSE
NC score	0.016636 (rank : 344)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	303	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SOS1_MOUSE
NC score	0.016421 (rank : 345)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	303	Target Neighborhood Hits	281	Shared Neighborhood Hits	13
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

CBP_MOUSE
NC score	0.015790 (rank : 346)	θ value	0.813845 (rank : 214)
Query Neighborhood Hits	303	Target Neighborhood Hits	1051	Shared Neighborhood Hits	44
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ATX2L_MOUSE
NC score	0.015641 (rank : 347)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	303	Target Neighborhood Hits	401	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CUTL2_HUMAN
NC score	0.015614 (rank : 348)	θ value	1.06291 (rank : 219)
Query Neighborhood Hits	303	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

SSBP4_HUMAN
NC score	0.015289 (rank : 349)	θ value	0.365318 (rank : 201)
Query Neighborhood Hits	303	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PCLO_HUMAN
NC score	0.014615 (rank : 350)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	303	Target Neighborhood Hits	2046	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SRRM1_MOUSE
NC score	0.014378 (rank : 351)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	303	Target Neighborhood Hits	966	Shared Neighborhood Hits	49
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

UBP2L_MOUSE
NC score	0.013943 (rank : 352)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	303	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

BAG4_MOUSE
NC score	0.013583 (rank : 353)	θ value	1.81305 (rank : 234)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CI61, Q3TRL9, Q91VT5, Q9CWG2	Gene names	Bag4, Sodd
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

UBP2L_HUMAN
NC score	0.013529 (rank : 354)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

RFIP1_HUMAN
NC score	0.013434 (rank : 355)	θ value	0.21417 (rank : 188)
Query Neighborhood Hits	303	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

WASF3_MOUSE
NC score	0.013328 (rank : 356)	θ value	0.21417 (rank : 189)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

BAG4_HUMAN
NC score	0.013212 (rank : 357)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	303	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

ATX2L_HUMAN
NC score	0.013166 (rank : 358)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	303	Target Neighborhood Hits	443	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

DDIT3_MOUSE
NC score	0.013122 (rank : 359)	θ value	1.81305 (rank : 236)
Query Neighborhood Hits	303	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	P35639, Q91YW9	Gene names	Ddit3, Chop, Gadd153
Domain Architecture	No domain graphic available
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

CT151_HUMAN
NC score	0.012918 (rank : 360)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	303	Target Neighborhood Hits	382	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

PRGC1_MOUSE
NC score	0.012512 (rank : 361)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	303	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

PRGC1_HUMAN
NC score	0.012467 (rank : 362)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	303	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

AFF1_HUMAN
NC score	0.012045 (rank : 363)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	303	Target Neighborhood Hits	506	Shared Neighborhood Hits	31
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

STON2_HUMAN
NC score	0.012022 (rank : 364)	θ value	0.365318 (rank : 202)
Query Neighborhood Hits	303	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

JIP1_HUMAN
NC score	0.011399 (rank : 365)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

YLPM1_HUMAN
NC score	0.010988 (rank : 366)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	303	Target Neighborhood Hits	670	Shared Neighborhood Hits	36
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

LARP1_HUMAN
NC score	0.010562 (rank : 367)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	303	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

WTAP_MOUSE
NC score	0.010503 (rank : 368)	θ value	3.0926 (rank : 260)
Query Neighborhood Hits	303	Target Neighborhood Hits	250	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

RC3H1_HUMAN
NC score	0.010213 (rank : 369)	θ value	0.365318 (rank : 200)
Query Neighborhood Hits	303	Target Neighborhood Hits	433	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

WTAP_HUMAN
NC score	0.009337 (rank : 370)	θ value	3.0926 (rank : 259)
Query Neighborhood Hits	303	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

RAPH1_HUMAN
NC score	0.009242 (rank : 371)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	303	Target Neighborhood Hits	593	Shared Neighborhood Hits	35
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PRG4_HUMAN
NC score	0.009135 (rank : 372)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	303	Target Neighborhood Hits	764	Shared Neighborhood Hits	36
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PO6F2_HUMAN
NC score	0.008806 (rank : 373)	θ value	0.0961366 (rank : 181)
Query Neighborhood Hits	303	Target Neighborhood Hits	618	Shared Neighborhood Hits	26
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

JIP1_MOUSE
NC score	0.008456 (rank : 374)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	303	Target Neighborhood Hits	259	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

EVI2B_MOUSE
NC score	0.008203 (rank : 375)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	303	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

CD44_MOUSE
NC score	0.008065 (rank : 376)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	303	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

TM108_MOUSE
NC score	0.007776 (rank : 377)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	303	Target Neighborhood Hits	336	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

SRTD2_HUMAN
NC score	0.007770 (rank : 378)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	303	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

PO6F2_MOUSE
NC score	0.007469 (rank : 379)	θ value	0.21417 (rank : 187)
Query Neighborhood Hits	303	Target Neighborhood Hits	639	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SARDH_MOUSE
NC score	0.007090 (rank : 380)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	303	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LB7	Gene names	Sardh
Domain Architecture	No domain graphic available
Description	Sarcosine dehydrogenase, mitochondrial precursor (EC 1.5.99.1) (SarDH).

GLU2B_MOUSE
NC score	0.006331 (rank : 381)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	303	Target Neighborhood Hits	357	Shared Neighborhood Hits	9
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CARD6_HUMAN
NC score	0.006164 (rank : 382)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	303	Target Neighborhood Hits	145	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

BAZ2B_HUMAN
NC score	0.006053 (rank : 383)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	303	Target Neighborhood Hits	803	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

GLYG2_HUMAN
NC score	0.005889 (rank : 384)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	303	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

NHS_HUMAN
NC score	0.005855 (rank : 385)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

HUWE1_HUMAN
NC score	0.005604 (rank : 386)	θ value	5.27518 (rank : 274)
Query Neighborhood Hits	303	Target Neighborhood Hits	443	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.005540 (rank : 387)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	303	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

MBD5_HUMAN
NC score	0.004824 (rank : 388)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	303	Target Neighborhood Hits	176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

NKTR_HUMAN
NC score	0.004386 (rank : 389)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	303	Target Neighborhood Hits	658	Shared Neighborhood Hits	23
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

ACE_MOUSE
NC score	0.004205 (rank : 390)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	303	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

LIRB4_HUMAN
NC score	0.003937 (rank : 391)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	303	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

ACE_HUMAN
NC score	0.003698 (rank : 392)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	303	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

SMG7_HUMAN
NC score	0.002734 (rank : 393)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	303	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

PDE8A_MOUSE
NC score	0.002278 (rank : 394)	θ value	3.0926 (rank : 257)
Query Neighborhood Hits	303	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

TRAF7_HUMAN
NC score	0.002203 (rank : 395)	θ value	3.0926 (rank : 258)
Query Neighborhood Hits	303	Target Neighborhood Hits	482	Shared Neighborhood Hits	12
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

KBTBA_HUMAN
NC score	0.000539 (rank : 396)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	303	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

MRIP_HUMAN
NC score	-0.000135 (rank : 397)	θ value	5.27518 (rank : 276)
Query Neighborhood Hits	303	Target Neighborhood Hits	578	Shared Neighborhood Hits	12
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

NR4A3_MOUSE
NC score	-0.000496 (rank : 398)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	303	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

RARB_MOUSE
NC score	-0.001839 (rank : 399)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

ANR41_HUMAN
NC score	-0.002696 (rank : 400)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	303	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

NOTC1_MOUSE
NC score	-0.004823 (rank : 401)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	303	Target Neighborhood Hits	916	Shared Neighborhood Hits	15
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_HUMAN
NC score	-0.005192 (rank : 402)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	303	Target Neighborhood Hits	906	Shared Neighborhood Hits	10
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SALL4_HUMAN
NC score	-0.008494 (rank : 403)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	303	Target Neighborhood Hits	799	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJQ4	Gene names	SALL4
Domain Architecture
Description	Sal-like protein 4 (Zinc finger protein SALL4).

MARK2_MOUSE
NC score	-0.009242 (rank : 404)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	303	Target Neighborhood Hits	1018	Shared Neighborhood Hits	19
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

M3K12_HUMAN
NC score	-0.009266 (rank : 405)	θ value	0.62314 (rank : 207)
Query Neighborhood Hits	303	Target Neighborhood Hits	940	Shared Neighborhood Hits	8
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MARK1_HUMAN
NC score	-0.009966 (rank : 406)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	303	Target Neighborhood Hits	887	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0L2, Q5VTF9, Q5VTG0, Q96SW9, Q9P251	Gene names	MARK1, KIAA1477, MARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 1).