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Network neighborhood for query Sequence : DVL2_MOUSE

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DVL2_MOUSE
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DVL2_HUMAN
θ value	0 (rank : 1)	NC score	0.990127 (rank : 2)
Query Neighborhood Hits	233	Target Neighborhood Hits	223	Shared Neighborhood Hits	180
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	233	Target Neighborhood Hits	233	Shared Neighborhood Hits	233
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_MOUSE
θ value	0 (rank : 3)	NC score	0.978573 (rank : 3)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
θ value	1.11414e-183 (rank : 4)	NC score	0.978046 (rank : 4)
Query Neighborhood Hits	233	Target Neighborhood Hits	194	Shared Neighborhood Hits	137
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_HUMAN
θ value	5.94893e-161 (rank : 5)	NC score	0.973648 (rank : 6)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	127
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	5.03607e-160 (rank : 6)	NC score	0.973769 (rank : 5)
Query Neighborhood Hits	233	Target Neighborhood Hits	146	Shared Neighborhood Hits	125
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1L_HUMAN
θ value	1.79118e-157 (rank : 7)	NC score	0.972390 (rank : 7)
Query Neighborhood Hits	233	Target Neighborhood Hits	146	Shared Neighborhood Hits	122
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

LNX2_MOUSE
θ value	8.11959e-09 (rank : 8)	NC score	0.470090 (rank : 13)
Query Neighborhood Hits	233	Target Neighborhood Hits	407	Shared Neighborhood Hits	112
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PTN13_HUMAN
θ value	1.06045e-08 (rank : 9)	NC score	0.293078 (rank : 76)
Query Neighborhood Hits	233	Target Neighborhood Hits	471	Shared Neighborhood Hits	119
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PARD3_MOUSE
θ value	6.87365e-08 (rank : 10)	NC score	0.491962 (rank : 11)
Query Neighborhood Hits	233	Target Neighborhood Hits	290	Shared Neighborhood Hits	118
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

DLG2_MOUSE
θ value	8.97725e-08 (rank : 11)	NC score	0.435391 (rank : 21)
Query Neighborhood Hits	233	Target Neighborhood Hits	271	Shared Neighborhood Hits	114
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PARD3_HUMAN
θ value	1.17247e-07 (rank : 12)	NC score	0.494510 (rank : 9)
Query Neighborhood Hits	233	Target Neighborhood Hits	312	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DLG2_HUMAN
θ value	1.53129e-07 (rank : 13)	NC score	0.432419 (rank : 25)
Query Neighborhood Hits	233	Target Neighborhood Hits	279	Shared Neighborhood Hits	114
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_MOUSE
θ value	1.99992e-07 (rank : 14)	NC score	0.428781 (rank : 26)
Query Neighborhood Hits	233	Target Neighborhood Hits	274	Shared Neighborhood Hits	114
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

SYJ2B_HUMAN
θ value	2.61198e-07 (rank : 15)	NC score	0.568135 (rank : 8)
Query Neighborhood Hits	233	Target Neighborhood Hits	162	Shared Neighborhood Hits	107
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

DLG3_HUMAN
θ value	3.41135e-07 (rank : 16)	NC score	0.426029 (rank : 27)
Query Neighborhood Hits	233	Target Neighborhood Hits	269	Shared Neighborhood Hits	114
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG4_HUMAN
θ value	5.81887e-07 (rank : 17)	NC score	0.432954 (rank : 24)
Query Neighborhood Hits	233	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	5.81887e-07 (rank : 18)	NC score	0.433665 (rank : 23)
Query Neighborhood Hits	233	Target Neighborhood Hits	282	Shared Neighborhood Hits	115
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

INADL_HUMAN
θ value	5.81887e-07 (rank : 19)	NC score	0.473843 (rank : 12)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	115
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

PDZD2_HUMAN
θ value	7.59969e-07 (rank : 20)	NC score	0.457391 (rank : 18)
Query Neighborhood Hits	233	Target Neighborhood Hits	772	Shared Neighborhood Hits	140
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LNX2_HUMAN
θ value	9.92553e-07 (rank : 21)	NC score	0.463016 (rank : 16)
Query Neighborhood Hits	233	Target Neighborhood Hits	389	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

DLG1_HUMAN
θ value	1.29631e-06 (rank : 22)	NC score	0.422383 (rank : 28)
Query Neighborhood Hits	233	Target Neighborhood Hits	290	Shared Neighborhood Hits	115
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

MPDZ_HUMAN
θ value	1.69304e-06 (rank : 23)	NC score	0.468569 (rank : 14)
Query Neighborhood Hits	233	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

DLG1_MOUSE
θ value	3.77169e-06 (rank : 24)	NC score	0.421480 (rank : 29)
Query Neighborhood Hits	233	Target Neighborhood Hits	285	Shared Neighborhood Hits	115
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

INADL_MOUSE
θ value	3.77169e-06 (rank : 25)	NC score	0.463432 (rank : 15)
Query Neighborhood Hits	233	Target Neighborhood Hits	290	Shared Neighborhood Hits	116
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

AFAD_HUMAN
θ value	4.92598e-06 (rank : 26)	NC score	0.390580 (rank : 37)
Query Neighborhood Hits	233	Target Neighborhood Hits	689	Shared Neighborhood Hits	119
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PTN13_MOUSE
θ value	4.92598e-06 (rank : 27)	NC score	0.279514 (rank : 81)
Query Neighborhood Hits	233	Target Neighborhood Hits	426	Shared Neighborhood Hits	119
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

AXN2_MOUSE
θ value	6.43352e-06 (rank : 28)	NC score	0.246155 (rank : 91)
Query Neighborhood Hits	233	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

MPDZ_MOUSE
θ value	6.43352e-06 (rank : 29)	NC score	0.461194 (rank : 17)
Query Neighborhood Hits	233	Target Neighborhood Hits	298	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PAR3L_HUMAN
θ value	6.43352e-06 (rank : 30)	NC score	0.493177 (rank : 10)
Query Neighborhood Hits	233	Target Neighborhood Hits	297	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

LNX1_HUMAN
θ value	8.40245e-06 (rank : 31)	NC score	0.437217 (rank : 20)
Query Neighborhood Hits	233	Target Neighborhood Hits	379	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

AXN1_HUMAN
θ value	1.43324e-05 (rank : 32)	NC score	0.230702 (rank : 99)
Query Neighborhood Hits	233	Target Neighborhood Hits	99	Shared Neighborhood Hits	21
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AXN2_HUMAN
θ value	1.87187e-05 (rank : 33)	NC score	0.237756 (rank : 96)
Query Neighborhood Hits	233	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

LNX1_MOUSE
θ value	2.44474e-05 (rank : 34)	NC score	0.438951 (rank : 19)
Query Neighborhood Hits	233	Target Neighborhood Hits	377	Shared Neighborhood Hits	113
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

AXN1_MOUSE
θ value	3.19293e-05 (rank : 35)	NC score	0.214745 (rank : 109)
Query Neighborhood Hits	233	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

PDZK4_MOUSE
θ value	3.19293e-05 (rank : 36)	NC score	0.395794 (rank : 34)
Query Neighborhood Hits	233	Target Neighborhood Hits	165	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

GRIP2_HUMAN
θ value	4.1701e-05 (rank : 37)	NC score	0.434732 (rank : 22)
Query Neighborhood Hits	233	Target Neighborhood Hits	256	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

STXB4_MOUSE
θ value	4.1701e-05 (rank : 38)	NC score	0.339573 (rank : 58)
Query Neighborhood Hits	233	Target Neighborhood Hits	629	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

LAP4_HUMAN
θ value	5.44631e-05 (rank : 39)	NC score	0.283789 (rank : 78)
Query Neighborhood Hits	233	Target Neighborhood Hits	608	Shared Neighborhood Hits	123
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PZRN4_HUMAN
θ value	0.000121331 (rank : 40)	NC score	0.389264 (rank : 40)
Query Neighborhood Hits	233	Target Neighborhood Hits	438	Shared Neighborhood Hits	109
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

LAP4_MOUSE
θ value	0.00020696 (rank : 41)	NC score	0.284651 (rank : 77)
Query Neighborhood Hits	233	Target Neighborhood Hits	590	Shared Neighborhood Hits	122
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PDZK4_HUMAN
θ value	0.00020696 (rank : 42)	NC score	0.398588 (rank : 33)
Query Neighborhood Hits	233	Target Neighborhood Hits	165	Shared Neighborhood Hits	97
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

NOS1_MOUSE
θ value	0.000270298 (rank : 43)	NC score	0.231496 (rank : 98)
Query Neighborhood Hits	233	Target Neighborhood Hits	155	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PZRN3_HUMAN
θ value	0.000461057 (rank : 44)	NC score	0.374929 (rank : 47)
Query Neighborhood Hits	233	Target Neighborhood Hits	461	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.000461057 (rank : 45)	NC score	0.375429 (rank : 46)
Query Neighborhood Hits	233	Target Neighborhood Hits	447	Shared Neighborhood Hits	108
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZO3_HUMAN
θ value	0.000602161 (rank : 46)	NC score	0.391173 (rank : 36)
Query Neighborhood Hits	233	Target Neighborhood Hits	219	Shared Neighborhood Hits	112
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

BCL9_HUMAN
θ value	0.000786445 (rank : 47)	NC score	0.084695 (rank : 170)
Query Neighborhood Hits	233	Target Neighborhood Hits	1008	Shared Neighborhood Hits	67
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

GRIP1_HUMAN
θ value	0.000786445 (rank : 48)	NC score	0.405866 (rank : 30)
Query Neighborhood Hits	233	Target Neighborhood Hits	231	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

STXB4_HUMAN
θ value	0.000786445 (rank : 49)	NC score	0.320148 (rank : 69)
Query Neighborhood Hits	233	Target Neighborhood Hits	616	Shared Neighborhood Hits	96
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

GRIP1_MOUSE
θ value	0.00102713 (rank : 50)	NC score	0.403587 (rank : 31)
Query Neighborhood Hits	233	Target Neighborhood Hits	241	Shared Neighborhood Hits	115
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

NEB2_HUMAN
θ value	0.00102713 (rank : 51)	NC score	0.302990 (rank : 72)
Query Neighborhood Hits	233	Target Neighborhood Hits	883	Shared Neighborhood Hits	103
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.00102713 (rank : 52)	NC score	0.298987 (rank : 74)
Query Neighborhood Hits	233	Target Neighborhood Hits	889	Shared Neighborhood Hits	105
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB1_HUMAN
θ value	0.00134147 (rank : 53)	NC score	0.317925 (rank : 71)
Query Neighborhood Hits	233	Target Neighborhood Hits	829	Shared Neighborhood Hits	109
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NOS1_HUMAN
θ value	0.00175202 (rank : 54)	NC score	0.239966 (rank : 95)
Query Neighborhood Hits	233	Target Neighborhood Hits	218	Shared Neighborhood Hits	110
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

ZO1_MOUSE
θ value	0.00175202 (rank : 55)	NC score	0.347842 (rank : 54)
Query Neighborhood Hits	233	Target Neighborhood Hits	453	Shared Neighborhood Hits	121
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

K1849_MOUSE
θ value	0.00228821 (rank : 56)	NC score	0.346752 (rank : 56)
Query Neighborhood Hits	233	Target Neighborhood Hits	335	Shared Neighborhood Hits	124
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTG2_HUMAN
θ value	0.00228821 (rank : 57)	NC score	0.350272 (rank : 53)
Query Neighborhood Hits	233	Target Neighborhood Hits	191	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

WHRN_MOUSE
θ value	0.00228821 (rank : 58)	NC score	0.372175 (rank : 48)
Query Neighborhood Hits	233	Target Neighborhood Hits	412	Shared Neighborhood Hits	128
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
θ value	0.00298849 (rank : 59)	NC score	0.370320 (rank : 49)
Query Neighborhood Hits	233	Target Neighborhood Hits	325	Shared Neighborhood Hits	125
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

ZO3_MOUSE
θ value	0.00390308 (rank : 60)	NC score	0.379019 (rank : 45)
Query Neighborhood Hits	233	Target Neighborhood Hits	224	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

RPGF6_HUMAN
θ value	0.00509761 (rank : 61)	NC score	0.251924 (rank : 87)
Query Neighborhood Hits	233	Target Neighborhood Hits	266	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

K1849_HUMAN
θ value	0.00665767 (rank : 62)	NC score	0.347578 (rank : 55)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO1_HUMAN
θ value	0.00665767 (rank : 63)	NC score	0.344007 (rank : 57)
Query Neighborhood Hits	233	Target Neighborhood Hits	474	Shared Neighborhood Hits	124
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RPGF2_HUMAN
θ value	0.00869519 (rank : 64)	NC score	0.228961 (rank : 100)
Query Neighborhood Hits	233	Target Neighborhood Hits	242	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SNTG2_MOUSE
θ value	0.00869519 (rank : 65)	NC score	0.329237 (rank : 65)
Query Neighborhood Hits	233	Target Neighborhood Hits	176	Shared Neighborhood Hits	99
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

CO5A2_HUMAN
θ value	0.0148317 (rank : 66)	NC score	0.046709 (rank : 206)
Query Neighborhood Hits	233	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

LIN7A_HUMAN
θ value	0.0193708 (rank : 67)	NC score	0.389329 (rank : 39)
Query Neighborhood Hits	233	Target Neighborhood Hits	193	Shared Neighborhood Hits	111
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.0193708 (rank : 68)	NC score	0.389159 (rank : 41)
Query Neighborhood Hits	233	Target Neighborhood Hits	193	Shared Neighborhood Hits	111
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_HUMAN
θ value	0.0193708 (rank : 69)	NC score	0.391511 (rank : 35)
Query Neighborhood Hits	233	Target Neighborhood Hits	200	Shared Neighborhood Hits	114
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

CEL_HUMAN
θ value	0.0252991 (rank : 70)	NC score	0.029812 (rank : 249)
Query Neighborhood Hits	233	Target Neighborhood Hits	896	Shared Neighborhood Hits	52
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

LIN7B_MOUSE
θ value	0.0252991 (rank : 71)	NC score	0.389446 (rank : 38)
Query Neighborhood Hits	233	Target Neighborhood Hits	200	Shared Neighborhood Hits	114
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
θ value	0.0252991 (rank : 72)	NC score	0.388525 (rank : 42)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.0252991 (rank : 73)	NC score	0.388525 (rank : 43)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

USH1C_HUMAN
θ value	0.0252991 (rank : 74)	NC score	0.385392 (rank : 44)
Query Neighborhood Hits	233	Target Neighborhood Hits	327	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

ZO2_HUMAN
θ value	0.0252991 (rank : 75)	NC score	0.335824 (rank : 61)
Query Neighborhood Hits	233	Target Neighborhood Hits	289	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	0.0252991 (rank : 76)	NC score	0.337917 (rank : 60)
Query Neighborhood Hits	233	Target Neighborhood Hits	296	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DLG5_HUMAN
θ value	0.0330416 (rank : 77)	NC score	0.259767 (rank : 86)
Query Neighborhood Hits	233	Target Neighborhood Hits	1088	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

LAP2_HUMAN
θ value	0.0330416 (rank : 78)	NC score	0.165185 (rank : 120)
Query Neighborhood Hits	233	Target Neighborhood Hits	499	Shared Neighborhood Hits	85
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
θ value	0.0330416 (rank : 79)	NC score	0.159719 (rank : 126)
Query Neighborhood Hits	233	Target Neighborhood Hits	482	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LRRC7_HUMAN
θ value	0.0330416 (rank : 80)	NC score	0.171373 (rank : 118)
Query Neighborhood Hits	233	Target Neighborhood Hits	423	Shared Neighborhood Hits	87
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.0330416 (rank : 81)	NC score	0.170824 (rank : 119)
Query Neighborhood Hits	233	Target Neighborhood Hits	416	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

USH1C_MOUSE
θ value	0.0330416 (rank : 82)	NC score	0.362174 (rank : 50)
Query Neighborhood Hits	233	Target Neighborhood Hits	557	Shared Neighborhood Hits	124
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

CTND2_MOUSE
θ value	0.0431538 (rank : 83)	NC score	0.032113 (rank : 243)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

MAGI1_HUMAN
θ value	0.0431538 (rank : 84)	NC score	0.332235 (rank : 64)
Query Neighborhood Hits	233	Target Neighborhood Hits	388	Shared Neighborhood Hits	118
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

BAT2_HUMAN
θ value	0.0563607 (rank : 85)	NC score	0.095528 (rank : 163)
Query Neighborhood Hits	233	Target Neighborhood Hits	931	Shared Neighborhood Hits	85
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DEPD5_HUMAN
θ value	0.0563607 (rank : 86)	NC score	0.133602 (rank : 140)
Query Neighborhood Hits	233	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	O75140, Q5K3V5, Q5THY9, Q5THZ0, Q5THZ1, Q5THZ3, Q68DR1, Q6MZX3, Q6PEZ1, Q9UGV8, Q9UH13	Gene names	DEPDC5, KIAA0645
Domain Architecture
Description	DEP domain-containing protein 5.

IL16_HUMAN
θ value	0.0563607 (rank : 87)	NC score	0.402475 (rank : 32)
Query Neighborhood Hits	233	Target Neighborhood Hits	207	Shared Neighborhood Hits	114
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MAGI1_MOUSE
θ value	0.0736092 (rank : 88)	NC score	0.333905 (rank : 62)
Query Neighborhood Hits	233	Target Neighborhood Hits	403	Shared Neighborhood Hits	119
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	0.0736092 (rank : 89)	NC score	0.320099 (rank : 70)
Query Neighborhood Hits	233	Target Neighborhood Hits	373	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	0.0736092 (rank : 90)	NC score	0.321878 (rank : 67)
Query Neighborhood Hits	233	Target Neighborhood Hits	370	Shared Neighborhood Hits	120
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

RGS11_HUMAN
θ value	0.0736092 (rank : 91)	NC score	0.122002 (rank : 146)
Query Neighborhood Hits	233	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

SNTG1_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.298569 (rank : 75)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_MOUSE
θ value	0.0736092 (rank : 93)	NC score	0.299526 (rank : 73)
Query Neighborhood Hits	233	Target Neighborhood Hits	179	Shared Neighborhood Hits	104
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDZD7_HUMAN
θ value	0.0961366 (rank : 94)	NC score	0.333903 (rank : 63)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PREX1_HUMAN
θ value	0.0961366 (rank : 95)	NC score	0.059982 (rank : 187)
Query Neighborhood Hits	233	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

CO2A1_HUMAN
θ value	0.125558 (rank : 96)	NC score	0.044405 (rank : 209)
Query Neighborhood Hits	233	Target Neighborhood Hits	486	Shared Neighborhood Hits	48
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	0.125558 (rank : 97)	NC score	0.044499 (rank : 208)
Query Neighborhood Hits	233	Target Neighborhood Hits	483	Shared Neighborhood Hits	50
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MPP4_MOUSE
θ value	0.163984 (rank : 98)	NC score	0.240617 (rank : 94)
Query Neighborhood Hits	233	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

SATB1_HUMAN
θ value	0.163984 (rank : 99)	NC score	0.035552 (rank : 231)
Query Neighborhood Hits	233	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB1_MOUSE
θ value	0.163984 (rank : 100)	NC score	0.036386 (rank : 227)
Query Neighborhood Hits	233	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

T22D4_HUMAN
θ value	0.21417 (rank : 101)	NC score	0.032678 (rank : 242)
Query Neighborhood Hits	233	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TCF20_HUMAN
θ value	0.21417 (rank : 102)	NC score	0.039592 (rank : 220)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

BSCL2_MOUSE
θ value	0.279714 (rank : 103)	NC score	0.046042 (rank : 207)
Query Neighborhood Hits	233	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

CFAB_HUMAN
θ value	0.279714 (rank : 104)	NC score	0.014170 (rank : 290)
Query Neighborhood Hits	233	Target Neighborhood Hits	251	Shared Neighborhood Hits	5
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

RGS9_HUMAN
θ value	0.279714 (rank : 105)	NC score	0.098784 (rank : 161)
Query Neighborhood Hits	233	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

TTLL5_MOUSE
θ value	0.279714 (rank : 106)	NC score	0.030665 (rank : 247)
Query Neighborhood Hits	233	Target Neighborhood Hits	150	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

BAT2_MOUSE
θ value	0.365318 (rank : 107)	NC score	0.084717 (rank : 169)
Query Neighborhood Hits	233	Target Neighborhood Hits	947	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO9A2_MOUSE
θ value	0.365318 (rank : 108)	NC score	0.040245 (rank : 218)
Query Neighborhood Hits	233	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

FHOD1_MOUSE
θ value	0.365318 (rank : 109)	NC score	0.028761 (rank : 251)
Query Neighborhood Hits	233	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

PDZ11_HUMAN
θ value	0.365318 (rank : 110)	NC score	0.353395 (rank : 52)
Query Neighborhood Hits	233	Target Neighborhood Hits	160	Shared Neighborhood Hits	91
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

ASXL1_HUMAN
θ value	0.47712 (rank : 111)	NC score	0.028441 (rank : 253)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

FOXN1_HUMAN
θ value	0.47712 (rank : 112)	NC score	0.019011 (rank : 274)
Query Neighborhood Hits	233	Target Neighborhood Hits	377	Shared Neighborhood Hits	23
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GGN_HUMAN
θ value	0.47712 (rank : 113)	NC score	0.057530 (rank : 189)
Query Neighborhood Hits	233	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

NU153_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.043391 (rank : 212)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

SC24C_HUMAN
θ value	0.47712 (rank : 115)	NC score	0.042875 (rank : 213)
Query Neighborhood Hits	233	Target Neighborhood Hits	662	Shared Neighborhood Hits	47
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SNTA1_HUMAN
θ value	0.47712 (rank : 116)	NC score	0.283682 (rank : 79)
Query Neighborhood Hits	233	Target Neighborhood Hits	186	Shared Neighborhood Hits	104
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

BCL7C_MOUSE
θ value	0.62314 (rank : 117)	NC score	0.031964 (rank : 244)
Query Neighborhood Hits	233	Target Neighborhood Hits	170	Shared Neighborhood Hits	21
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

MUC1_HUMAN
θ value	0.62314 (rank : 118)	NC score	0.041671 (rank : 215)
Query Neighborhood Hits	233	Target Neighborhood Hits	975	Shared Neighborhood Hits	61
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RGS9_MOUSE
θ value	0.62314 (rank : 119)	NC score	0.096353 (rank : 162)
Query Neighborhood Hits	233	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

CO4A2_HUMAN
θ value	0.813845 (rank : 120)	NC score	0.037362 (rank : 224)
Query Neighborhood Hits	233	Target Neighborhood Hits	454	Shared Neighborhood Hits	44
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

MEF2B_MOUSE
θ value	0.813845 (rank : 121)	NC score	0.026818 (rank : 259)
Query Neighborhood Hits	233	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MPP4_HUMAN
θ value	0.813845 (rank : 122)	NC score	0.249420 (rank : 89)
Query Neighborhood Hits	233	Target Neighborhood Hits	205	Shared Neighborhood Hits	100
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

OGFR_HUMAN
θ value	0.813845 (rank : 123)	NC score	0.036354 (rank : 228)
Query Neighborhood Hits	233	Target Neighborhood Hits	1582	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCLO_MOUSE
θ value	0.813845 (rank : 124)	NC score	0.131471 (rank : 141)
Query Neighborhood Hits	233	Target Neighborhood Hits	2275	Shared Neighborhood Hits	170
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SETBP_HUMAN
θ value	0.813845 (rank : 125)	NC score	0.047318 (rank : 205)
Query Neighborhood Hits	233	Target Neighborhood Hits	305	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SSBP4_HUMAN
θ value	0.813845 (rank : 126)	NC score	0.037832 (rank : 223)
Query Neighborhood Hits	233	Target Neighborhood Hits	753	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PDZ11_MOUSE
θ value	1.06291 (rank : 127)	NC score	0.338958 (rank : 59)
Query Neighborhood Hits	233	Target Neighborhood Hits	154	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RIMB1_MOUSE
θ value	1.06291 (rank : 128)	NC score	0.014403 (rank : 287)
Query Neighborhood Hits	233	Target Neighborhood Hits	1376	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SNTB1_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.268351 (rank : 84)
Query Neighborhood Hits	233	Target Neighborhood Hits	157	Shared Neighborhood Hits	100
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.266921 (rank : 85)
Query Neighborhood Hits	233	Target Neighborhood Hits	160	Shared Neighborhood Hits	100
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

TITIN_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.001347 (rank : 304)
Query Neighborhood Hits	233	Target Neighborhood Hits	2923	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DICER_MOUSE
θ value	1.38821 (rank : 132)	NC score	0.021299 (rank : 271)
Query Neighborhood Hits	233	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

IL16_MOUSE
θ value	1.38821 (rank : 133)	NC score	0.357203 (rank : 51)
Query Neighborhood Hits	233	Target Neighborhood Hits	189	Shared Neighborhood Hits	108
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PP1R8_MOUSE
θ value	1.38821 (rank : 134)	NC score	0.027459 (rank : 257)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

PSB1_HUMAN
θ value	1.38821 (rank : 135)	NC score	0.049186 (rank : 204)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P20618, Q9BWA8	Gene names	PSMB1, PSC5
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

PSB1_MOUSE
θ value	1.38821 (rank : 136)	NC score	0.049540 (rank : 202)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	O09061, Q62038, Q62039	Gene names	Psmb1
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

SETBP_MOUSE
θ value	1.38821 (rank : 137)	NC score	0.041092 (rank : 217)
Query Neighborhood Hits	233	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SNTA1_MOUSE
θ value	1.38821 (rank : 138)	NC score	0.268406 (rank : 83)
Query Neighborhood Hits	233	Target Neighborhood Hits	170	Shared Neighborhood Hits	100
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

CAC1H_HUMAN
θ value	1.81305 (rank : 139)	NC score	0.010958 (rank : 295)
Query Neighborhood Hits	233	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CBP_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.028282 (rank : 254)
Query Neighborhood Hits	233	Target Neighborhood Hits	941	Shared Neighborhood Hits	52
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CO4A2_MOUSE
θ value	1.81305 (rank : 141)	NC score	0.035093 (rank : 232)
Query Neighborhood Hits	233	Target Neighborhood Hits	492	Shared Neighborhood Hits	46
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO7A1_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.030014 (rank : 248)
Query Neighborhood Hits	233	Target Neighborhood Hits	807	Shared Neighborhood Hits	58
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DACH1_MOUSE
θ value	1.81305 (rank : 143)	NC score	0.027816 (rank : 256)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DEPD5_MOUSE
θ value	1.81305 (rank : 144)	NC score	0.084775 (rank : 168)
Query Neighborhood Hits	233	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	P61460	Gene names	Depdc5, Kiaa0645
Domain Architecture
Description	DEP domain-containing protein 5.

IF4B_MOUSE
θ value	1.81305 (rank : 145)	NC score	0.025763 (rank : 263)
Query Neighborhood Hits	233	Target Neighborhood Hits	368	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MPP3_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.225902 (rank : 105)
Query Neighborhood Hits	233	Target Neighborhood Hits	171	Shared Neighborhood Hits	96
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	1.81305 (rank : 147)	NC score	0.227585 (rank : 102)
Query Neighborhood Hits	233	Target Neighborhood Hits	165	Shared Neighborhood Hits	96
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MY18A_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.035010 (rank : 233)
Query Neighborhood Hits	233	Target Neighborhood Hits	1929	Shared Neighborhood Hits	105
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	1.81305 (rank : 149)	NC score	0.040041 (rank : 219)
Query Neighborhood Hits	233	Target Neighborhood Hits	1989	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NCOA6_HUMAN
θ value	1.81305 (rank : 150)	NC score	0.026434 (rank : 260)
Query Neighborhood Hits	233	Target Neighborhood Hits	1202	Shared Neighborhood Hits	65
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NUMBL_MOUSE
θ value	1.81305 (rank : 151)	NC score	0.015891 (rank : 284)
Query Neighborhood Hits	233	Target Neighborhood Hits	147	Shared Neighborhood Hits	12
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

PDZD6_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.157305 (rank : 127)
Query Neighborhood Hits	233	Target Neighborhood Hits	81	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PGCA_HUMAN
θ value	1.81305 (rank : 153)	NC score	0.022393 (rank : 269)
Query Neighborhood Hits	233	Target Neighborhood Hits	821	Shared Neighborhood Hits	41
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

RGS7_HUMAN
θ value	1.81305 (rank : 154)	NC score	0.053917 (rank : 194)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_MOUSE
θ value	1.81305 (rank : 155)	NC score	0.053259 (rank : 198)
Query Neighborhood Hits	233	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RIMS1_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.141429 (rank : 139)
Query Neighborhood Hits	233	Target Neighborhood Hits	437	Shared Neighborhood Hits	99
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SOX15_HUMAN
θ value	1.81305 (rank : 157)	NC score	0.012510 (rank : 292)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SP5_HUMAN
θ value	1.81305 (rank : 158)	NC score	-0.003532 (rank : 307)
Query Neighborhood Hits	233	Target Neighborhood Hits	832	Shared Neighborhood Hits	15
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

TX1B3_HUMAN
θ value	1.81305 (rank : 159)	NC score	0.323558 (rank : 66)
Query Neighborhood Hits	233	Target Neighborhood Hits	161	Shared Neighborhood Hits	99
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	1.81305 (rank : 160)	NC score	0.320791 (rank : 68)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

WNK1_HUMAN
θ value	1.81305 (rank : 161)	NC score	0.001931 (rank : 303)
Query Neighborhood Hits	233	Target Neighborhood Hits	1158	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ANK2_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.011754 (rank : 293)
Query Neighborhood Hits	233	Target Neighborhood Hits	1615	Shared Neighborhood Hits	55
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CCD45_MOUSE
θ value	2.36792 (rank : 163)	NC score	0.011187 (rank : 294)
Query Neighborhood Hits	233	Target Neighborhood Hits	663	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CTND2_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.022715 (rank : 267)
Query Neighborhood Hits	233	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DOK7_MOUSE
θ value	2.36792 (rank : 165)	NC score	0.043787 (rank : 211)
Query Neighborhood Hits	233	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

MARCO_MOUSE
θ value	2.36792 (rank : 166)	NC score	0.026110 (rank : 261)
Query Neighborhood Hits	233	Target Neighborhood Hits	242	Shared Neighborhood Hits	22
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

PICK1_HUMAN
θ value	2.36792 (rank : 167)	NC score	0.226161 (rank : 104)
Query Neighborhood Hits	233	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	2.36792 (rank : 168)	NC score	0.227714 (rank : 101)
Query Neighborhood Hits	233	Target Neighborhood Hits	131	Shared Neighborhood Hits	92
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

RIMS2_HUMAN
θ value	2.36792 (rank : 169)	NC score	0.114516 (rank : 152)
Query Neighborhood Hits	233	Target Neighborhood Hits	342	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	2.36792 (rank : 170)	NC score	0.112138 (rank : 155)
Query Neighborhood Hits	233	Target Neighborhood Hits	376	Shared Neighborhood Hits	86
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

TACC2_MOUSE
θ value	2.36792 (rank : 171)	NC score	0.018899 (rank : 275)
Query Neighborhood Hits	233	Target Neighborhood Hits	774	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TDRD6_MOUSE
θ value	2.36792 (rank : 172)	NC score	0.027135 (rank : 258)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	9
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

TROAP_HUMAN
θ value	2.36792 (rank : 173)	NC score	0.031210 (rank : 245)
Query Neighborhood Hits	233	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

WNK1_MOUSE
θ value	2.36792 (rank : 174)	NC score	0.000530 (rank : 305)
Query Neighborhood Hits	233	Target Neighborhood Hits	1179	Shared Neighborhood Hits	28
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

BSN_MOUSE
θ value	3.0926 (rank : 175)	NC score	0.038269 (rank : 222)
Query Neighborhood Hits	233	Target Neighborhood Hits	2057	Shared Neighborhood Hits	96
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CRSP7_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.029649 (rank : 250)
Query Neighborhood Hits	233	Target Neighborhood Hits	247	Shared Neighborhood Hits	31
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CSPG5_MOUSE
θ value	3.0926 (rank : 177)	NC score	0.016806 (rank : 282)
Query Neighborhood Hits	233	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

EFS_MOUSE
θ value	3.0926 (rank : 178)	NC score	0.022431 (rank : 268)
Query Neighborhood Hits	233	Target Neighborhood Hits	389	Shared Neighborhood Hits	30
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

NRX2A_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.014841 (rank : 285)
Query Neighborhood Hits	233	Target Neighborhood Hits	614	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.023442 (rank : 266)
Query Neighborhood Hits	233	Target Neighborhood Hits	481	Shared Neighborhood Hits	34
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NUP53_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.025649 (rank : 265)
Query Neighborhood Hits	233	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

RP3A_MOUSE
θ value	3.0926 (rank : 182)	NC score	0.013591 (rank : 291)
Query Neighborhood Hits	233	Target Neighborhood Hits	510	Shared Neighborhood Hits	39
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPGF5_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.042051 (rank : 214)
Query Neighborhood Hits	233	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

APBA1_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.202767 (rank : 112)
Query Neighborhood Hits	233	Target Neighborhood Hits	325	Shared Neighborhood Hits	111
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

ATG9A_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.014279 (rank : 288)
Query Neighborhood Hits	233	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z3C6, Q6P0N7, Q7Z317, Q7Z320, Q8NDK6, Q8WU65, Q9BVL5, Q9H6L1, Q9HAG7	Gene names	ATG9A, APG9L1
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 9A (APG9-like 1).

BAI2_HUMAN
θ value	4.03905 (rank : 186)	NC score	0.002377 (rank : 302)
Query Neighborhood Hits	233	Target Neighborhood Hits	332	Shared Neighborhood Hits	11
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CBP_MOUSE
θ value	4.03905 (rank : 187)	NC score	0.025757 (rank : 264)
Query Neighborhood Hits	233	Target Neighborhood Hits	1051	Shared Neighborhood Hits	52
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DACH1_HUMAN
θ value	4.03905 (rank : 188)	NC score	0.019260 (rank : 273)
Query Neighborhood Hits	233	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DIDO1_HUMAN
θ value	4.03905 (rank : 189)	NC score	0.034808 (rank : 235)
Query Neighborhood Hits	233	Target Neighborhood Hits	960	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EM55_HUMAN
θ value	4.03905 (rank : 190)	NC score	0.193368 (rank : 116)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	90
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	4.03905 (rank : 191)	NC score	0.193334 (rank : 117)
Query Neighborhood Hits	233	Target Neighborhood Hits	221	Shared Neighborhood Hits	88
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NIPBL_HUMAN
θ value	4.03905 (rank : 192)	NC score	0.018422 (rank : 276)
Query Neighborhood Hits	233	Target Neighborhood Hits	1311	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ASPX_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.032715 (rank : 241)
Query Neighborhood Hits	233	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

CO9A1_HUMAN
θ value	5.27518 (rank : 194)	NC score	0.032753 (rank : 240)
Query Neighborhood Hits	233	Target Neighborhood Hits	420	Shared Neighborhood Hits	42
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A3_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.033980 (rank : 236)
Query Neighborhood Hits	233	Target Neighborhood Hits	361	Shared Neighborhood Hits	38
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

FBX41_HUMAN
θ value	5.27518 (rank : 196)	NC score	0.014567 (rank : 286)
Query Neighborhood Hits	233	Target Neighborhood Hits	475	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FGD1_MOUSE
θ value	5.27518 (rank : 197)	NC score	0.010176 (rank : 296)
Query Neighborhood Hits	233	Target Neighborhood Hits	387	Shared Neighborhood Hits	37
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FILA_HUMAN
θ value	5.27518 (rank : 198)	NC score	0.044295 (rank : 210)
Query Neighborhood Hits	233	Target Neighborhood Hits	685	Shared Neighborhood Hits	34
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FYV1_HUMAN
θ value	5.27518 (rank : 199)	NC score	0.035633 (rank : 230)
Query Neighborhood Hits	233	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

IASPP_MOUSE
θ value	5.27518 (rank : 200)	NC score	0.016340 (rank : 283)
Query Neighborhood Hits	233	Target Neighborhood Hits	1024	Shared Neighborhood Hits	53
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF4B_HUMAN
θ value	5.27518 (rank : 201)	NC score	0.017911 (rank : 278)
Query Neighborhood Hits	233	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

LARP4_HUMAN
θ value	5.27518 (rank : 202)	NC score	0.021754 (rank : 270)
Query Neighborhood Hits	233	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LARP4_MOUSE
θ value	5.27518 (rank : 203)	NC score	0.025809 (rank : 262)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MPP5_HUMAN
θ value	5.27518 (rank : 204)	NC score	0.213337 (rank : 110)
Query Neighborhood Hits	233	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	5.27518 (rank : 205)	NC score	0.212966 (rank : 111)
Query Neighborhood Hits	233	Target Neighborhood Hits	226	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PRRT3_HUMAN
θ value	5.27518 (rank : 206)	NC score	0.038301 (rank : 221)
Query Neighborhood Hits	233	Target Neighborhood Hits	998	Shared Neighborhood Hits	63
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RASF4_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.014247 (rank : 289)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2L5, Q86WH5, Q86WH6, Q86WH7, Q8N5A9, Q8TCK6	Gene names	RASSF4
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 4.

COBA1_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.036634 (rank : 226)
Query Neighborhood Hits	233	Target Neighborhood Hits	491	Shared Neighborhood Hits	50
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	6.88961 (rank : 209)	NC score	0.036094 (rank : 229)
Query Neighborhood Hits	233	Target Neighborhood Hits	487	Shared Neighborhood Hits	50
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COJA1_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.033683 (rank : 237)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	39
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

MAST4_HUMAN
θ value	6.88961 (rank : 211)	NC score	0.017557 (rank : 279)
Query Neighborhood Hits	233	Target Neighborhood Hits	1804	Shared Neighborhood Hits	125
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MEFV_HUMAN
θ value	6.88961 (rank : 212)	NC score	0.009542 (rank : 297)
Query Neighborhood Hits	233	Target Neighborhood Hits	431	Shared Neighborhood Hits	17
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PLEK2_HUMAN
θ value	6.88961 (rank : 213)	NC score	0.041158 (rank : 216)
Query Neighborhood Hits	233	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PTN22_MOUSE
θ value	6.88961 (rank : 214)	NC score	0.017353 (rank : 280)
Query Neighborhood Hits	233	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

SOX15_MOUSE
θ value	6.88961 (rank : 215)	NC score	0.005854 (rank : 301)
Query Neighborhood Hits	233	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

YLPM1_MOUSE
θ value	6.88961 (rank : 216)	NC score	0.028756 (rank : 252)
Query Neighborhood Hits	233	Target Neighborhood Hits	505	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

APBA2_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.193842 (rank : 115)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	101
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	8.99809 (rank : 218)	NC score	0.194536 (rank : 114)
Query Neighborhood Hits	233	Target Neighborhood Hits	219	Shared Neighborhood Hits	103
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

BIM_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.018161 (rank : 277)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

BSN_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.037354 (rank : 225)
Query Neighborhood Hits	233	Target Neighborhood Hits	1537	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CO4A3_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.034814 (rank : 234)
Query Neighborhood Hits	233	Target Neighborhood Hits	421	Shared Neighborhood Hits	48
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO9A1_MOUSE
θ value	8.99809 (rank : 222)	NC score	0.032926 (rank : 239)
Query Neighborhood Hits	233	Target Neighborhood Hits	477	Shared Neighborhood Hits	46
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COBA2_MOUSE
θ value	8.99809 (rank : 223)	NC score	0.031146 (rank : 246)
Query Neighborhood Hits	233	Target Neighborhood Hits	501	Shared Neighborhood Hits	50
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

FYV1_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.028254 (rank : 255)
Query Neighborhood Hits	233	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GA2L2_MOUSE
θ value	8.99809 (rank : 225)	NC score	0.016974 (rank : 281)
Query Neighborhood Hits	233	Target Neighborhood Hits	395	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

IWS1_MOUSE
θ value	8.99809 (rank : 226)	NC score	0.019403 (rank : 272)
Query Neighborhood Hits	233	Target Neighborhood Hits	1258	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYO15_MOUSE
θ value	8.99809 (rank : 227)	NC score	0.007758 (rank : 299)
Query Neighborhood Hits	233	Target Neighborhood Hits	467	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NHERF_MOUSE
θ value	8.99809 (rank : 228)	NC score	0.234619 (rank : 97)
Query Neighborhood Hits	233	Target Neighborhood Hits	195	Shared Neighborhood Hits	96
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

RPGF4_MOUSE
θ value	8.99809 (rank : 229)	NC score	0.049261 (rank : 203)
Query Neighborhood Hits	233	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

TAOK1_HUMAN
θ value	8.99809 (rank : 230)	NC score	-0.003377 (rank : 306)
Query Neighborhood Hits	233	Target Neighborhood Hits	1734	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TCGAP_HUMAN
θ value	8.99809 (rank : 231)	NC score	0.033599 (rank : 238)
Query Neighborhood Hits	233	Target Neighborhood Hits	872	Shared Neighborhood Hits	56
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TXLNA_MOUSE
θ value	8.99809 (rank : 232)	NC score	0.009539 (rank : 298)
Query Neighborhood Hits	233	Target Neighborhood Hits	846	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UBP53_MOUSE
θ value	8.99809 (rank : 233)	NC score	0.007704 (rank : 300)
Query Neighborhood Hits	233	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

APBA3_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.163596 (rank : 122)
Query Neighborhood Hits	233	Target Neighborhood Hits	201	Shared Neighborhood Hits	93
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.142767 (rank : 137)
Query Neighborhood Hits	233	Target Neighborhood Hits	174	Shared Neighborhood Hits	89
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APXL_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.106857 (rank : 158)
Query Neighborhood Hits	233	Target Neighborhood Hits	553	Shared Neighborhood Hits	85
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARHGB_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.129985 (rank : 142)
Query Neighborhood Hits	233	Target Neighborhood Hits	375	Shared Neighborhood Hits	110
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.111493 (rank : 157)
Query Neighborhood Hits	233	Target Neighborhood Hits	351	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.112074 (rank : 156)
Query Neighborhood Hits	233	Target Neighborhood Hits	344	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CSKP_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.057049 (rank : 191)
Query Neighborhood Hits	233	Target Neighborhood Hits	1022	Shared Neighborhood Hits	91
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.054806 (rank : 192)
Query Neighborhood Hits	233	Target Neighborhood Hits	1027	Shared Neighborhood Hits	92
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

GIPC1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.089818 (rank : 167)
Query Neighborhood Hits	233	Target Neighborhood Hits	91	Shared Neighborhood Hits	65
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

GIPC1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.094239 (rank : 164)
Query Neighborhood Hits	233	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

GIPC2_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.069673 (rank : 176)
Query Neighborhood Hits	233	Target Neighborhood Hits	93	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

GOPC_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.278803 (rank : 82)
Query Neighborhood Hits	233	Target Neighborhood Hits	377	Shared Neighborhood Hits	107
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.283521 (rank : 80)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GRASP_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.127931 (rank : 143)
Query Neighborhood Hits	233	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.123649 (rank : 144)
Query Neighborhood Hits	233	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

KGUA_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.119165 (rank : 148)
Query Neighborhood Hits	233	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.120265 (rank : 147)
Query Neighborhood Hits	233	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LDB3_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.063929 (rank : 183)
Query Neighborhood Hits	233	Target Neighborhood Hits	497	Shared Neighborhood Hits	91
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.063957 (rank : 182)
Query Neighborhood Hits	233	Target Neighborhood Hits	510	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LMO7_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.051214 (rank : 200)
Query Neighborhood Hits	233	Target Neighborhood Hits	507	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MPP2_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.147302 (rank : 135)
Query Neighborhood Hits	233	Target Neighborhood Hits	173	Shared Neighborhood Hits	65
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.149477 (rank : 132)
Query Neighborhood Hits	233	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.148511 (rank : 133)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.150078 (rank : 131)
Query Neighborhood Hits	233	Target Neighborhood Hits	187	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NHERF_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.221442 (rank : 106)
Query Neighborhood Hits	233	Target Neighborhood Hits	190	Shared Neighborhood Hits	95
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.226738 (rank : 103)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.220214 (rank : 107)
Query Neighborhood Hits	233	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PAR6A_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.153579 (rank : 128)
Query Neighborhood Hits	233	Target Neighborhood Hits	119	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.153209 (rank : 129)
Query Neighborhood Hits	233	Target Neighborhood Hits	115	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.162272 (rank : 123)
Query Neighborhood Hits	233	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.161582 (rank : 124)
Query Neighborhood Hits	233	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.164215 (rank : 121)
Query Neighborhood Hits	233	Target Neighborhood Hits	159	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.161118 (rank : 125)
Query Neighborhood Hits	233	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDLI1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.064443 (rank : 181)
Query Neighborhood Hits	233	Target Neighborhood Hits	242	Shared Neighborhood Hits	55
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.065484 (rank : 180)
Query Neighborhood Hits	233	Target Neighborhood Hits	213	Shared Neighborhood Hits	55
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI2_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.141677 (rank : 138)
Query Neighborhood Hits	233	Target Neighborhood Hits	245	Shared Neighborhood Hits	81
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.119000 (rank : 149)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI3_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.077125 (rank : 172)
Query Neighborhood Hits	233	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.067099 (rank : 179)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	62
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.071758 (rank : 175)
Query Neighborhood Hits	233	Target Neighborhood Hits	245	Shared Neighborhood Hits	63
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.072808 (rank : 173)
Query Neighborhood Hits	233	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI5_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.060293 (rank : 185)
Query Neighborhood Hits	233	Target Neighborhood Hits	322	Shared Neighborhood Hits	70
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.060145 (rank : 186)
Query Neighborhood Hits	233	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.052510 (rank : 199)
Query Neighborhood Hits	233	Target Neighborhood Hits	547	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.247642 (rank : 90)
Query Neighborhood Hits	233	Target Neighborhood Hits	190	Shared Neighborhood Hits	95
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD1_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.249727 (rank : 88)
Query Neighborhood Hits	233	Target Neighborhood Hits	191	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.216051 (rank : 108)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.199690 (rank : 113)
Query Neighborhood Hits	233	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PRAX_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.059921 (rank : 188)
Query Neighborhood Hits	233	Target Neighborhood Hits	199	Shared Neighborhood Hits	47
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRP1_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.050558 (rank : 201)
Query Neighborhood Hits	233	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PSCBP_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.102713 (rank : 160)
Query Neighborhood Hits	233	Target Neighborhood Hits	123	Shared Neighborhood Hits	66
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSCBP_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.116003 (rank : 150)
Query Neighborhood Hits	233	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PTN3_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.057407 (rank : 190)
Query Neighborhood Hits	233	Target Neighborhood Hits	258	Shared Neighborhood Hits	72
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.063311 (rank : 184)
Query Neighborhood Hits	233	Target Neighborhood Hits	303	Shared Neighborhood Hits	82
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RGS12_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.145409 (rank : 136)
Query Neighborhood Hits	233	Target Neighborhood Hits	333	Shared Neighborhood Hits	110
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS3_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.054635 (rank : 193)
Query Neighborhood Hits	233	Target Neighborhood Hits	1375	Shared Neighborhood Hits	100
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.053640 (rank : 195)
Query Neighborhood Hits	233	Target Neighborhood Hits	1621	Shared Neighborhood Hits	108
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.103681 (rank : 159)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.114732 (rank : 151)
Query Neighborhood Hits	233	Target Neighborhood Hits	154	Shared Neighborhood Hits	71
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RNF41_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.053268 (rank : 197)
Query Neighborhood Hits	233	Target Neighborhood Hits	226	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.053397 (rank : 196)
Query Neighborhood Hits	233	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SDCB1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.150778 (rank : 130)
Query Neighborhood Hits	233	Target Neighborhood Hits	150	Shared Neighborhood Hits	95
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.148346 (rank : 134)
Query Neighborhood Hits	233	Target Neighborhood Hits	144	Shared Neighborhood Hits	89
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.114359 (rank : 153)
Query Neighborhood Hits	233	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.122497 (rank : 145)
Query Neighborhood Hits	233	Target Neighborhood Hits	118	Shared Neighborhood Hits	78
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SHAN1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.068373 (rank : 177)
Query Neighborhood Hits	233	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.093710 (rank : 165)
Query Neighborhood Hits	233	Target Neighborhood Hits	346	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.081690 (rank : 171)
Query Neighborhood Hits	233	Target Neighborhood Hits	446	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SNTB2_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.245538 (rank : 92)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	106
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.245011 (rank : 93)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	104
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SYNP2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.068254 (rank : 178)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYNP2_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.093231 (rank : 166)
Query Neighborhood Hits	233	Target Neighborhood Hits	252	Shared Neighborhood Hits	80
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYP2L_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.112877 (rank : 154)
Query Neighborhood Hits	233	Target Neighborhood Hits	400	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.071926 (rank : 174)
Query Neighborhood Hits	233	Target Neighborhood Hits	289	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

Hits sorted by NC score

DVL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	233	Target Neighborhood Hits	233	Shared Neighborhood Hits	233
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.990127 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	233	Target Neighborhood Hits	223	Shared Neighborhood Hits	180
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_MOUSE
NC score	0.978573 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	137
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
NC score	0.978046 (rank : 4)	θ value	1.11414e-183 (rank : 4)
Query Neighborhood Hits	233	Target Neighborhood Hits	194	Shared Neighborhood Hits	137
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_MOUSE
NC score	0.973769 (rank : 5)	θ value	5.03607e-160 (rank : 6)
Query Neighborhood Hits	233	Target Neighborhood Hits	146	Shared Neighborhood Hits	125
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_HUMAN
NC score	0.973648 (rank : 6)	θ value	5.94893e-161 (rank : 5)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	127
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1L_HUMAN
NC score	0.972390 (rank : 7)	θ value	1.79118e-157 (rank : 7)
Query Neighborhood Hits	233	Target Neighborhood Hits	146	Shared Neighborhood Hits	122
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

SYJ2B_HUMAN
NC score	0.568135 (rank : 8)	θ value	2.61198e-07 (rank : 15)
Query Neighborhood Hits	233	Target Neighborhood Hits	162	Shared Neighborhood Hits	107
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

PARD3_HUMAN
NC score	0.494510 (rank : 9)	θ value	1.17247e-07 (rank : 12)
Query Neighborhood Hits	233	Target Neighborhood Hits	312	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PAR3L_HUMAN
NC score	0.493177 (rank : 10)	θ value	6.43352e-06 (rank : 30)
Query Neighborhood Hits	233	Target Neighborhood Hits	297	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_MOUSE
NC score	0.491962 (rank : 11)	θ value	6.87365e-08 (rank : 10)
Query Neighborhood Hits	233	Target Neighborhood Hits	290	Shared Neighborhood Hits	118
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

INADL_HUMAN
NC score	0.473843 (rank : 12)	θ value	5.81887e-07 (rank : 19)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	115
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LNX2_MOUSE
NC score	0.470090 (rank : 13)	θ value	8.11959e-09 (rank : 8)
Query Neighborhood Hits	233	Target Neighborhood Hits	407	Shared Neighborhood Hits	112
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MPDZ_HUMAN
NC score	0.468569 (rank : 14)	θ value	1.69304e-06 (rank : 23)
Query Neighborhood Hits	233	Target Neighborhood Hits	261	Shared Neighborhood Hits	114
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

INADL_MOUSE
NC score	0.463432 (rank : 15)	θ value	3.77169e-06 (rank : 25)
Query Neighborhood Hits	233	Target Neighborhood Hits	290	Shared Neighborhood Hits	116
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LNX2_HUMAN
NC score	0.463016 (rank : 16)	θ value	9.92553e-07 (rank : 21)
Query Neighborhood Hits	233	Target Neighborhood Hits	389	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MPDZ_MOUSE
NC score	0.461194 (rank : 17)	θ value	6.43352e-06 (rank : 29)
Query Neighborhood Hits	233	Target Neighborhood Hits	298	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PDZD2_HUMAN
NC score	0.457391 (rank : 18)	θ value	7.59969e-07 (rank : 20)
Query Neighborhood Hits	233	Target Neighborhood Hits	772	Shared Neighborhood Hits	140
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LNX1_MOUSE
NC score	0.438951 (rank : 19)	θ value	2.44474e-05 (rank : 34)
Query Neighborhood Hits	233	Target Neighborhood Hits	377	Shared Neighborhood Hits	113
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.437217 (rank : 20)	θ value	8.40245e-06 (rank : 31)
Query Neighborhood Hits	233	Target Neighborhood Hits	379	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

DLG2_MOUSE
NC score	0.435391 (rank : 21)	θ value	8.97725e-08 (rank : 11)
Query Neighborhood Hits	233	Target Neighborhood Hits	271	Shared Neighborhood Hits	114
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GRIP2_HUMAN
NC score	0.434732 (rank : 22)	θ value	4.1701e-05 (rank : 37)
Query Neighborhood Hits	233	Target Neighborhood Hits	256	Shared Neighborhood Hits	117
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG4_MOUSE
NC score	0.433665 (rank : 23)	θ value	5.81887e-07 (rank : 18)
Query Neighborhood Hits	233	Target Neighborhood Hits	282	Shared Neighborhood Hits	115
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.432954 (rank : 24)	θ value	5.81887e-07 (rank : 17)
Query Neighborhood Hits	233	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_HUMAN
NC score	0.432419 (rank : 25)	θ value	1.53129e-07 (rank : 13)
Query Neighborhood Hits	233	Target Neighborhood Hits	279	Shared Neighborhood Hits	114
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_MOUSE
NC score	0.428781 (rank : 26)	θ value	1.99992e-07 (rank : 14)
Query Neighborhood Hits	233	Target Neighborhood Hits	274	Shared Neighborhood Hits	114
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.426029 (rank : 27)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	233	Target Neighborhood Hits	269	Shared Neighborhood Hits	114
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
NC score	0.422383 (rank : 28)	θ value	1.29631e-06 (rank : 22)
Query Neighborhood Hits	233	Target Neighborhood Hits	290	Shared Neighborhood Hits	115
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
NC score	0.421480 (rank : 29)	θ value	3.77169e-06 (rank : 24)
Query Neighborhood Hits	233	Target Neighborhood Hits	285	Shared Neighborhood Hits	115
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

GRIP1_HUMAN
NC score	0.405866 (rank : 30)	θ value	0.000786445 (rank : 48)
Query Neighborhood Hits	233	Target Neighborhood Hits	231	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.403587 (rank : 31)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	233	Target Neighborhood Hits	241	Shared Neighborhood Hits	115
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

IL16_HUMAN
NC score	0.402475 (rank : 32)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	233	Target Neighborhood Hits	207	Shared Neighborhood Hits	114
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZK4_HUMAN
NC score	0.398588 (rank : 33)	θ value	0.00020696 (rank : 42)
Query Neighborhood Hits	233	Target Neighborhood Hits	165	Shared Neighborhood Hits	97
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
NC score	0.395794 (rank : 34)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	233	Target Neighborhood Hits	165	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

LIN7B_HUMAN
NC score	0.391511 (rank : 35)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	233	Target Neighborhood Hits	200	Shared Neighborhood Hits	114
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

ZO3_HUMAN
NC score	0.391173 (rank : 36)	θ value	0.000602161 (rank : 46)
Query Neighborhood Hits	233	Target Neighborhood Hits	219	Shared Neighborhood Hits	112
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

AFAD_HUMAN
NC score	0.390580 (rank : 37)	θ value	4.92598e-06 (rank : 26)
Query Neighborhood Hits	233	Target Neighborhood Hits	689	Shared Neighborhood Hits	119
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

LIN7B_MOUSE
NC score	0.389446 (rank : 38)	θ value	0.0252991 (rank : 71)
Query Neighborhood Hits	233	Target Neighborhood Hits	200	Shared Neighborhood Hits	114
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_HUMAN
NC score	0.389329 (rank : 39)	θ value	0.0193708 (rank : 67)
Query Neighborhood Hits	233	Target Neighborhood Hits	193	Shared Neighborhood Hits	111
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

PZRN4_HUMAN
NC score	0.389264 (rank : 40)	θ value	0.000121331 (rank : 40)
Query Neighborhood Hits	233	Target Neighborhood Hits	438	Shared Neighborhood Hits	109
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

LIN7A_MOUSE
NC score	0.389159 (rank : 41)	θ value	0.0193708 (rank : 68)
Query Neighborhood Hits	233	Target Neighborhood Hits	193	Shared Neighborhood Hits	111
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7C_HUMAN
NC score	0.388525 (rank : 42)	θ value	0.0252991 (rank : 72)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.388525 (rank : 43)	θ value	0.0252991 (rank : 73)
Query Neighborhood Hits	233	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

USH1C_HUMAN
NC score	0.385392 (rank : 44)	θ value	0.0252991 (rank : 74)
Query Neighborhood Hits	233	Target Neighborhood Hits	327	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

ZO3_MOUSE
NC score	0.379019 (rank : 45)	θ value	0.00390308 (rank : 60)
Query Neighborhood Hits	233	Target Neighborhood Hits	224	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PZRN3_MOUSE
NC score	0.375429 (rank : 46)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	233	Target Neighborhood Hits	447	Shared Neighborhood Hits	108
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.374929 (rank : 47)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	233	Target Neighborhood Hits	461	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

WHRN_MOUSE
NC score	0.372175 (rank : 48)	θ value	0.00228821 (rank : 58)
Query Neighborhood Hits	233	Target Neighborhood Hits	412	Shared Neighborhood Hits	128
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
NC score	0.370320 (rank : 49)	θ value	0.00298849 (rank : 59)
Query Neighborhood Hits	233	Target Neighborhood Hits	325	Shared Neighborhood Hits	125
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

USH1C_MOUSE
NC score	0.362174 (rank : 50)	θ value	0.0330416 (rank : 82)
Query Neighborhood Hits	233	Target Neighborhood Hits	557	Shared Neighborhood Hits	124
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

IL16_MOUSE
NC score	0.357203 (rank : 51)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	233	Target Neighborhood Hits	189	Shared Neighborhood Hits	108
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZ11_HUMAN
NC score	0.353395 (rank : 52)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	233	Target Neighborhood Hits	160	Shared Neighborhood Hits	91
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SNTG2_HUMAN
NC score	0.350272 (rank : 53)	θ value	0.00228821 (rank : 57)
Query Neighborhood Hits	233	Target Neighborhood Hits	191	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

ZO1_MOUSE
NC score	0.347842 (rank : 54)	θ value	0.00175202 (rank : 55)
Query Neighborhood Hits	233	Target Neighborhood Hits	453	Shared Neighborhood Hits	121
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

K1849_HUMAN
NC score	0.347578 (rank : 55)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
NC score	0.346752 (rank : 56)	θ value	0.00228821 (rank : 56)
Query Neighborhood Hits	233	Target Neighborhood Hits	335	Shared Neighborhood Hits	124
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO1_HUMAN
NC score	0.344007 (rank : 57)	θ value	0.00665767 (rank : 63)
Query Neighborhood Hits	233	Target Neighborhood Hits	474	Shared Neighborhood Hits	124
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

STXB4_MOUSE
NC score	0.339573 (rank : 58)	θ value	4.1701e-05 (rank : 38)
Query Neighborhood Hits	233	Target Neighborhood Hits	629	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PDZ11_MOUSE
NC score	0.338958 (rank : 59)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	233	Target Neighborhood Hits	154	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

ZO2_MOUSE
NC score	0.337917 (rank : 60)	θ value	0.0252991 (rank : 76)
Query Neighborhood Hits	233	Target Neighborhood Hits	296	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_HUMAN
NC score	0.335824 (rank : 61)	θ value	0.0252991 (rank : 75)
Query Neighborhood Hits	233	Target Neighborhood Hits	289	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

MAGI1_MOUSE
NC score	0.333905 (rank : 62)	θ value	0.0736092 (rank : 88)
Query Neighborhood Hits	233	Target Neighborhood Hits	403	Shared Neighborhood Hits	119
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PDZD7_HUMAN
NC score	0.333903 (rank : 63)	θ value	0.0961366 (rank : 94)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

MAGI1_HUMAN
NC score	0.332235 (rank : 64)	θ value	0.0431538 (rank : 84)
Query Neighborhood Hits	233	Target Neighborhood Hits	388	Shared Neighborhood Hits	118
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

SNTG2_MOUSE
NC score	0.329237 (rank : 65)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	233	Target Neighborhood Hits	176	Shared Neighborhood Hits	99
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

TX1B3_HUMAN
NC score	0.323558 (rank : 66)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	233	Target Neighborhood Hits	161	Shared Neighborhood Hits	99
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

MAGI2_MOUSE
NC score	0.321878 (rank : 67)	θ value	0.0736092 (rank : 90)
Query Neighborhood Hits	233	Target Neighborhood Hits	370	Shared Neighborhood Hits	120
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

TX1B3_MOUSE
NC score	0.320791 (rank : 68)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

STXB4_HUMAN
NC score	0.320148 (rank : 69)	θ value	0.000786445 (rank : 49)
Query Neighborhood Hits	233	Target Neighborhood Hits	616	Shared Neighborhood Hits	96
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MAGI2_HUMAN
NC score	0.320099 (rank : 70)	θ value	0.0736092 (rank : 89)
Query Neighborhood Hits	233	Target Neighborhood Hits	373	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

NEB1_HUMAN
NC score	0.317925 (rank : 71)	θ value	0.00134147 (rank : 53)
Query Neighborhood Hits	233	Target Neighborhood Hits	829	Shared Neighborhood Hits	109
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
NC score	0.302990 (rank : 72)	θ value	0.00102713 (rank : 51)
Query Neighborhood Hits	233	Target Neighborhood Hits	883	Shared Neighborhood Hits	103
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SNTG1_MOUSE
NC score	0.299526 (rank : 73)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	233	Target Neighborhood Hits	179	Shared Neighborhood Hits	104
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

NEB2_MOUSE
NC score	0.298987 (rank : 74)	θ value	0.00102713 (rank : 52)
Query Neighborhood Hits	233	Target Neighborhood Hits	889	Shared Neighborhood Hits	105
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SNTG1_HUMAN
NC score	0.298569 (rank : 75)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PTN13_HUMAN
NC score	0.293078 (rank : 76)	θ value	1.06045e-08 (rank : 9)
Query Neighborhood Hits	233	Target Neighborhood Hits	471	Shared Neighborhood Hits	119
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

LAP4_MOUSE
NC score	0.284651 (rank : 77)	θ value	0.00020696 (rank : 41)
Query Neighborhood Hits	233	Target Neighborhood Hits	590	Shared Neighborhood Hits	122
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LAP4_HUMAN
NC score	0.283789 (rank : 78)	θ value	5.44631e-05 (rank : 39)
Query Neighborhood Hits	233	Target Neighborhood Hits	608	Shared Neighborhood Hits	123
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

SNTA1_HUMAN
NC score	0.283682 (rank : 79)	θ value	0.47712 (rank : 116)
Query Neighborhood Hits	233	Target Neighborhood Hits	186	Shared Neighborhood Hits	104
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

GOPC_MOUSE
NC score	0.283521 (rank : 80)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PTN13_MOUSE
NC score	0.279514 (rank : 81)	θ value	4.92598e-06 (rank : 27)
Query Neighborhood Hits	233	Target Neighborhood Hits	426	Shared Neighborhood Hits	119
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

GOPC_HUMAN
NC score	0.278803 (rank : 82)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	233	Target Neighborhood Hits	377	Shared Neighborhood Hits	107
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTA1_MOUSE
NC score	0.268406 (rank : 83)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	233	Target Neighborhood Hits	170	Shared Neighborhood Hits	100
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTB1_HUMAN
NC score	0.268351 (rank : 84)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	233	Target Neighborhood Hits	157	Shared Neighborhood Hits	100
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.266921 (rank : 85)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	233	Target Neighborhood Hits	160	Shared Neighborhood Hits	100
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

DLG5_HUMAN
NC score	0.259767 (rank : 86)	θ value	0.0330416 (rank : 77)
Query Neighborhood Hits	233	Target Neighborhood Hits	1088	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

RPGF6_HUMAN
NC score	0.251924 (rank : 87)	θ value	0.00509761 (rank : 61)
Query Neighborhood Hits	233	Target Neighborhood Hits	266	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PDZD1_MOUSE
NC score	0.249727 (rank : 88)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	233	Target Neighborhood Hits	191	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

MPP4_HUMAN
NC score	0.249420 (rank : 89)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	233	Target Neighborhood Hits	205	Shared Neighborhood Hits	100
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDZD1_HUMAN
NC score	0.247642 (rank : 90)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	233	Target Neighborhood Hits	190	Shared Neighborhood Hits	95
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

AXN2_MOUSE
NC score	0.246155 (rank : 91)	θ value	6.43352e-06 (rank : 28)
Query Neighborhood Hits	233	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

SNTB2_HUMAN
NC score	0.245538 (rank : 92)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	106
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
NC score	0.245011 (rank : 93)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	233	Target Neighborhood Hits	181	Shared Neighborhood Hits	104
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

MPP4_MOUSE
NC score	0.240617 (rank : 94)	θ value	0.163984 (rank : 98)
Query Neighborhood Hits	233	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NOS1_HUMAN
NC score	0.239966 (rank : 95)	θ value	0.00175202 (rank : 54)
Query Neighborhood Hits	233	Target Neighborhood Hits	218	Shared Neighborhood Hits	110
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

AXN2_HUMAN
NC score	0.237756 (rank : 96)	θ value	1.87187e-05 (rank : 33)
Query Neighborhood Hits	233	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

NHERF_MOUSE
NC score	0.234619 (rank : 97)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	233	Target Neighborhood Hits	195	Shared Neighborhood Hits	96
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NOS1_MOUSE
NC score	0.231496 (rank : 98)	θ value	0.000270298 (rank : 43)
Query Neighborhood Hits	233	Target Neighborhood Hits	155	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

AXN1_HUMAN
NC score	0.230702 (rank : 99)	θ value	1.43324e-05 (rank : 32)
Query Neighborhood Hits	233	Target Neighborhood Hits	99	Shared Neighborhood Hits	21
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

RPGF2_HUMAN
NC score	0.228961 (rank : 100)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	233	Target Neighborhood Hits	242	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

PICK1_MOUSE
NC score	0.227714 (rank : 101)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	233	Target Neighborhood Hits	131	Shared Neighborhood Hits	92
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

MPP3_MOUSE
NC score	0.227585 (rank : 102)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	233	Target Neighborhood Hits	165	Shared Neighborhood Hits	96
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

NHRF2_HUMAN
NC score	0.226738 (rank : 103)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PICK1_HUMAN
NC score	0.226161 (rank : 104)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	233	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

MPP3_HUMAN
NC score	0.225902 (rank : 105)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	233	Target Neighborhood Hits	171	Shared Neighborhood Hits	96
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

NHERF_HUMAN
NC score	0.221442 (rank : 106)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	233	Target Neighborhood Hits	190	Shared Neighborhood Hits	95
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
NC score	0.220214 (rank : 107)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	233	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD3_HUMAN
NC score	0.216051 (rank : 108)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

AXN1_MOUSE
NC score	0.214745 (rank : 109)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	233	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

MPP5_HUMAN
NC score	0.213337 (rank : 110)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	233	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.212966 (rank : 111)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	233	Target Neighborhood Hits	226	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

APBA1_HUMAN
NC score	0.202767 (rank : 112)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	233	Target Neighborhood Hits	325	Shared Neighborhood Hits	111
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PDZD3_MOUSE
NC score	0.199690 (rank : 113)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	233	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

APBA2_MOUSE
NC score	0.194536 (rank : 114)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	233	Target Neighborhood Hits	219	Shared Neighborhood Hits	103
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.193842 (rank : 115)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	101
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

EM55_HUMAN
NC score	0.193368 (rank : 116)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	90
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.193334 (rank : 117)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	233	Target Neighborhood Hits	221	Shared Neighborhood Hits	88
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

LRRC7_HUMAN
NC score	0.171373 (rank : 118)	θ value	0.0330416 (rank : 80)
Query Neighborhood Hits	233	Target Neighborhood Hits	423	Shared Neighborhood Hits	87
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.170824 (rank : 119)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	233	Target Neighborhood Hits	416	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LAP2_HUMAN
NC score	0.165185 (rank : 120)	θ value	0.0330416 (rank : 78)
Query Neighborhood Hits	233	Target Neighborhood Hits	499	Shared Neighborhood Hits	85
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PAR6G_HUMAN
NC score	0.164215 (rank : 121)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	233	Target Neighborhood Hits	159	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

APBA3_HUMAN
NC score	0.163596 (rank : 122)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	233	Target Neighborhood Hits	201	Shared Neighborhood Hits	93
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6B_HUMAN
NC score	0.162272 (rank : 123)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	233	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
NC score	0.161582 (rank : 124)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	233	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_MOUSE
NC score	0.161118 (rank : 125)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	233	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

LAP2_MOUSE
NC score	0.159719 (rank : 126)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	233	Target Neighborhood Hits	482	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDZD6_HUMAN
NC score	0.157305 (rank : 127)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	233	Target Neighborhood Hits	81	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PAR6A_HUMAN
NC score	0.153579 (rank : 128)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	233	Target Neighborhood Hits	119	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
NC score	0.153209 (rank : 129)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	233	Target Neighborhood Hits	115	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

SDCB1_HUMAN
NC score	0.150778 (rank : 130)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	233	Target Neighborhood Hits	150	Shared Neighborhood Hits	95
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

MPP6_MOUSE
NC score	0.150078 (rank : 131)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	233	Target Neighborhood Hits	187	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP2_MOUSE
NC score	0.149477 (rank : 132)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	233	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_HUMAN
NC score	0.148511 (rank : 133)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	233	Target Neighborhood Hits	180	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

SDCB1_MOUSE
NC score	0.148346 (rank : 134)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	233	Target Neighborhood Hits	144	Shared Neighborhood Hits	89
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

MPP2_HUMAN
NC score	0.147302 (rank : 135)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	233	Target Neighborhood Hits	173	Shared Neighborhood Hits	65
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

RGS12_HUMAN
NC score	0.145409 (rank : 136)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	233	Target Neighborhood Hits	333	Shared Neighborhood Hits	110
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

APBA3_MOUSE
NC score	0.142767 (rank : 137)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	233	Target Neighborhood Hits	174	Shared Neighborhood Hits	89
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PDLI2_HUMAN
NC score	0.141677 (rank : 138)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	233	Target Neighborhood Hits	245	Shared Neighborhood Hits	81
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

RIMS1_HUMAN
NC score	0.141429 (rank : 139)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	233	Target Neighborhood Hits	437	Shared Neighborhood Hits	99
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

DEPD5_HUMAN
NC score	0.133602 (rank : 140)	θ value	0.0563607 (rank : 86)
Query Neighborhood Hits	233	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	O75140, Q5K3V5, Q5THY9, Q5THZ0, Q5THZ1, Q5THZ3, Q68DR1, Q6MZX3, Q6PEZ1, Q9UGV8, Q9UH13	Gene names	DEPDC5, KIAA0645
Domain Architecture
Description	DEP domain-containing protein 5.

PCLO_MOUSE
NC score	0.131471 (rank : 141)	θ value	0.813845 (rank : 124)
Query Neighborhood Hits	233	Target Neighborhood Hits	2275	Shared Neighborhood Hits	170
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ARHGB_HUMAN
NC score	0.129985 (rank : 142)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	233	Target Neighborhood Hits	375	Shared Neighborhood Hits	110
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

GRASP_HUMAN
NC score	0.127931 (rank : 143)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	233	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.123649 (rank : 144)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	233	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

SDCB2_MOUSE
NC score	0.122497 (rank : 145)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	233	Target Neighborhood Hits	118	Shared Neighborhood Hits	78
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RGS11_HUMAN
NC score	0.122002 (rank : 146)	θ value	0.0736092 (rank : 91)
Query Neighborhood Hits	233	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

KGUA_MOUSE
NC score	0.120265 (rank : 147)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	233	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.119165 (rank : 148)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	233	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

PDLI2_MOUSE
NC score	0.119000 (rank : 149)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	233	Target Neighborhood Hits	220	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PSCBP_MOUSE
NC score	0.116003 (rank : 150)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	233	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RHPN1_MOUSE
NC score	0.114732 (rank : 151)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	233	Target Neighborhood Hits	154	Shared Neighborhood Hits	71
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RIMS2_HUMAN
NC score	0.114516 (rank : 152)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	233	Target Neighborhood Hits	342	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SDCB2_HUMAN
NC score	0.114359 (rank : 153)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	233	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SYP2L_HUMAN
NC score	0.112877 (rank : 154)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	233	Target Neighborhood Hits	400	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

RIMS2_MOUSE
NC score	0.112138 (rank : 155)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	233	Target Neighborhood Hits	376	Shared Neighborhood Hits	86
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ARHGC_MOUSE
NC score	0.112074 (rank : 156)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	233	Target Neighborhood Hits	344	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
NC score	0.111493 (rank : 157)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	233	Target Neighborhood Hits	351	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

APXL_HUMAN
NC score	0.106857 (rank : 158)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	233	Target Neighborhood Hits	553	Shared Neighborhood Hits	85
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RHPN1_HUMAN
NC score	0.103681 (rank : 159)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	233	Target Neighborhood Hits	158	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PSCBP_HUMAN
NC score	0.102713 (rank : 160)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	233	Target Neighborhood Hits	123	Shared Neighborhood Hits	66
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RGS9_HUMAN
NC score	0.098784 (rank : 161)	θ value	0.279714 (rank : 105)
Query Neighborhood Hits	233	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_MOUSE
NC score	0.096353 (rank : 162)	θ value	0.62314 (rank : 119)
Query Neighborhood Hits	233	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

BAT2_HUMAN
NC score	0.095528 (rank : 163)	θ value	0.0563607 (rank : 85)
Query Neighborhood Hits	233	Target Neighborhood Hits	931	Shared Neighborhood Hits	85
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GIPC1_MOUSE
NC score	0.094239 (rank : 164)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	233	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

SHAN2_HUMAN
NC score	0.093710 (rank : 165)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	233	Target Neighborhood Hits	346	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SYNP2_MOUSE
NC score	0.093231 (rank : 166)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	233	Target Neighborhood Hits	252	Shared Neighborhood Hits	80
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

GIPC1_HUMAN
NC score	0.089818 (rank : 167)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	233	Target Neighborhood Hits	91	Shared Neighborhood Hits	65
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

DEPD5_MOUSE
NC score	0.084775 (rank : 168)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	233	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	P61460	Gene names	Depdc5, Kiaa0645
Domain Architecture
Description	DEP domain-containing protein 5.

BAT2_MOUSE
NC score	0.084717 (rank : 169)	θ value	0.365318 (rank : 107)
Query Neighborhood Hits	233	Target Neighborhood Hits	947	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
NC score	0.084695 (rank : 170)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	233	Target Neighborhood Hits	1008	Shared Neighborhood Hits	67
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SHAN2_MOUSE
NC score	0.081690 (rank : 171)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	233	Target Neighborhood Hits	446	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PDLI3_HUMAN
NC score	0.077125 (rank : 172)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	233	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_MOUSE
NC score	0.072808 (rank : 173)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	233	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SYP2L_MOUSE
NC score	0.071926 (rank : 174)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	233	Target Neighborhood Hits	289	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDLI4_HUMAN
NC score	0.071758 (rank : 175)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	233	Target Neighborhood Hits	245	Shared Neighborhood Hits	63
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

GIPC2_HUMAN
NC score	0.069673 (rank : 176)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	233	Target Neighborhood Hits	93	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

SHAN1_HUMAN
NC score	0.068373 (rank : 177)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	233	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYNP2_HUMAN
NC score	0.068254 (rank : 178)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI3_MOUSE
NC score	0.067099 (rank : 179)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	233	Target Neighborhood Hits	197	Shared Neighborhood Hits	62
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI1_MOUSE
NC score	0.065484 (rank : 180)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	233	Target Neighborhood Hits	213	Shared Neighborhood Hits	55
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_HUMAN
NC score	0.064443 (rank : 181)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	233	Target Neighborhood Hits	242	Shared Neighborhood Hits	55
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

LDB3_MOUSE
NC score	0.063957 (rank : 182)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	233	Target Neighborhood Hits	510	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LDB3_HUMAN
NC score	0.063929 (rank : 183)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	233	Target Neighborhood Hits	497	Shared Neighborhood Hits	91
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PTN4_HUMAN
NC score	0.063311 (rank : 184)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	233	Target Neighborhood Hits	303	Shared Neighborhood Hits	82
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PDLI5_HUMAN
NC score	0.060293 (rank : 185)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	233	Target Neighborhood Hits	322	Shared Neighborhood Hits	70
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_MOUSE
NC score	0.060145 (rank : 186)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	233	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PREX1_HUMAN
NC score	0.059982 (rank : 187)	θ value	0.0961366 (rank : 95)
Query Neighborhood Hits	233	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRAX_MOUSE
NC score	0.059921 (rank : 188)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	233	Target Neighborhood Hits	199	Shared Neighborhood Hits	47
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

GGN_HUMAN
NC score	0.057530 (rank : 189)	θ value	0.47712 (rank : 113)
Query Neighborhood Hits	233	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PTN3_HUMAN
NC score	0.057407 (rank : 190)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	233	Target Neighborhood Hits	258	Shared Neighborhood Hits	72
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

CSKP_HUMAN
NC score	0.057049 (rank : 191)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	233	Target Neighborhood Hits	1022	Shared Neighborhood Hits	91
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.054806 (rank : 192)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	233	Target Neighborhood Hits	1027	Shared Neighborhood Hits	92
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

RGS3_HUMAN
NC score	0.054635 (rank : 193)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	233	Target Neighborhood Hits	1375	Shared Neighborhood Hits	100
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS7_HUMAN
NC score	0.053917 (rank : 194)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS3_MOUSE
NC score	0.053640 (rank : 195)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	233	Target Neighborhood Hits	1621	Shared Neighborhood Hits	108
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RNF41_MOUSE
NC score	0.053397 (rank : 196)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	233	Target Neighborhood Hits	224	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.053268 (rank : 197)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	233	Target Neighborhood Hits	226	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RGS7_MOUSE
NC score	0.053259 (rank : 198)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	233	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

PDLI7_HUMAN
NC score	0.052510 (rank : 199)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	233	Target Neighborhood Hits	547	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LMO7_HUMAN
NC score	0.051214 (rank : 200)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	233	Target Neighborhood Hits	507	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PRP1_HUMAN
NC score	0.050558 (rank : 201)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	233	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PSB1_MOUSE
NC score	0.049540 (rank : 202)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	O09061, Q62038, Q62039	Gene names	Psmb1
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

RPGF4_MOUSE
NC score	0.049261 (rank : 203)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	233	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

PSB1_HUMAN
NC score	0.049186 (rank : 204)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P20618, Q9BWA8	Gene names	PSMB1, PSC5
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

SETBP_HUMAN
NC score	0.047318 (rank : 205)	θ value	0.813845 (rank : 125)
Query Neighborhood Hits	233	Target Neighborhood Hits	305	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CO5A2_HUMAN
NC score	0.046709 (rank : 206)	θ value	0.0148317 (rank : 66)
Query Neighborhood Hits	233	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

BSCL2_MOUSE
NC score	0.046042 (rank : 207)	θ value	0.279714 (rank : 103)
Query Neighborhood Hits	233	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

CO2A1_MOUSE
NC score	0.044499 (rank : 208)	θ value	0.125558 (rank : 97)
Query Neighborhood Hits	233	Target Neighborhood Hits	483	Shared Neighborhood Hits	50
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_HUMAN
NC score	0.044405 (rank : 209)	θ value	0.125558 (rank : 96)
Query Neighborhood Hits	233	Target Neighborhood Hits	486	Shared Neighborhood Hits	48
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

FILA_HUMAN
NC score	0.044295 (rank : 210)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	233	Target Neighborhood Hits	685	Shared Neighborhood Hits	34
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DOK7_MOUSE
NC score	0.043787 (rank : 211)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	233	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

NU153_HUMAN
NC score	0.043391 (rank : 212)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

SC24C_HUMAN
NC score	0.042875 (rank : 213)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	233	Target Neighborhood Hits	662	Shared Neighborhood Hits	47
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

RPGF5_MOUSE
NC score	0.042051 (rank : 214)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	233	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

MUC1_HUMAN
NC score	0.041671 (rank : 215)	θ value	0.62314 (rank : 118)
Query Neighborhood Hits	233	Target Neighborhood Hits	975	Shared Neighborhood Hits	61
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PLEK2_HUMAN
NC score	0.041158 (rank : 216)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	233	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

SETBP_MOUSE
NC score	0.041092 (rank : 217)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	233	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CO9A2_MOUSE
NC score	0.040245 (rank : 218)	θ value	0.365318 (rank : 108)
Query Neighborhood Hits	233	Target Neighborhood Hits	279	Shared Neighborhood Hits	38
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

MY18A_MOUSE
NC score	0.040041 (rank : 219)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	233	Target Neighborhood Hits	1989	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TCF20_HUMAN
NC score	0.039592 (rank : 220)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PRRT3_HUMAN
NC score	0.038301 (rank : 221)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	233	Target Neighborhood Hits	998	Shared Neighborhood Hits	63
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_MOUSE
NC score	0.038269 (rank : 222)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	233	Target Neighborhood Hits	2057	Shared Neighborhood Hits	96
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SSBP4_HUMAN
NC score	0.037832 (rank : 223)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	233	Target Neighborhood Hits	753	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CO4A2_HUMAN
NC score	0.037362 (rank : 224)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	233	Target Neighborhood Hits	454	Shared Neighborhood Hits	44
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

BSN_HUMAN
NC score	0.037354 (rank : 225)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	233	Target Neighborhood Hits	1537	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

COBA1_HUMAN
NC score	0.036634 (rank : 226)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	233	Target Neighborhood Hits	491	Shared Neighborhood Hits	50
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SATB1_MOUSE
NC score	0.036386 (rank : 227)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	233	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

OGFR_HUMAN
NC score	0.036354 (rank : 228)	θ value	0.813845 (rank : 123)
Query Neighborhood Hits	233	Target Neighborhood Hits	1582	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

COBA1_MOUSE
NC score	0.036094 (rank : 229)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	233	Target Neighborhood Hits	487	Shared Neighborhood Hits	50
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

FYV1_HUMAN
NC score	0.035633 (rank : 230)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	233	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

SATB1_HUMAN
NC score	0.035552 (rank : 231)	θ value	0.163984 (rank : 99)
Query Neighborhood Hits	233	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

CO4A2_MOUSE
NC score	0.035093 (rank : 232)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	233	Target Neighborhood Hits	492	Shared Neighborhood Hits	46
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

MY18A_HUMAN
NC score	0.035010 (rank : 233)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	233	Target Neighborhood Hits	1929	Shared Neighborhood Hits	105
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CO4A3_HUMAN
NC score	0.034814 (rank : 234)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	233	Target Neighborhood Hits	421	Shared Neighborhood Hits	48
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

DIDO1_HUMAN
NC score	0.034808 (rank : 235)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	233	Target Neighborhood Hits	960	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CO9A3_HUMAN
NC score	0.033980 (rank : 236)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	233	Target Neighborhood Hits	361	Shared Neighborhood Hits	38
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COJA1_HUMAN
NC score	0.033683 (rank : 237)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	233	Target Neighborhood Hits	323	Shared Neighborhood Hits	39
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

TCGAP_HUMAN
NC score	0.033599 (rank : 238)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	233	Target Neighborhood Hits	872	Shared Neighborhood Hits	56
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CO9A1_MOUSE
NC score	0.032926 (rank : 239)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	233	Target Neighborhood Hits	477	Shared Neighborhood Hits	46
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_HUMAN
NC score	0.032753 (rank : 240)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	233	Target Neighborhood Hits	420	Shared Neighborhood Hits	42
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ASPX_HUMAN
NC score	0.032715 (rank : 241)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	233	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

T22D4_HUMAN
NC score	0.032678 (rank : 242)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	233	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

CTND2_MOUSE
NC score	0.032113 (rank : 243)	θ value	0.0431538 (rank : 83)
Query Neighborhood Hits	233	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

BCL7C_MOUSE
NC score	0.031964 (rank : 244)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	233	Target Neighborhood Hits	170	Shared Neighborhood Hits	21
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

TROAP_HUMAN
NC score	0.031210 (rank : 245)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	233	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

COBA2_MOUSE
NC score	0.031146 (rank : 246)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	233	Target Neighborhood Hits	501	Shared Neighborhood Hits	50
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

TTLL5_MOUSE
NC score	0.030665 (rank : 247)	θ value	0.279714 (rank : 106)
Query Neighborhood Hits	233	Target Neighborhood Hits	150	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

CO7A1_HUMAN
NC score	0.030014 (rank : 248)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	233	Target Neighborhood Hits	807	Shared Neighborhood Hits	58
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CEL_HUMAN
NC score	0.029812 (rank : 249)	θ value	0.0252991 (rank : 70)
Query Neighborhood Hits	233	Target Neighborhood Hits	896	Shared Neighborhood Hits	52
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CRSP7_HUMAN
NC score	0.029649 (rank : 250)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	233	Target Neighborhood Hits	247	Shared Neighborhood Hits	31
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

FHOD1_MOUSE
NC score	0.028761 (rank : 251)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	233	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

YLPM1_MOUSE
NC score	0.028756 (rank : 252)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	233	Target Neighborhood Hits	505	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ASXL1_HUMAN
NC score	0.028441 (rank : 253)	θ value	0.47712 (rank : 111)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CBP_HUMAN
NC score	0.028282 (rank : 254)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	233	Target Neighborhood Hits	941	Shared Neighborhood Hits	52
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FYV1_MOUSE
NC score	0.028254 (rank : 255)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	233	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

DACH1_MOUSE
NC score	0.027816 (rank : 256)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	233	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

PP1R8_MOUSE
NC score	0.027459 (rank : 257)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

TDRD6_MOUSE
NC score	0.027135 (rank : 258)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	233	Target Neighborhood Hits	82	Shared Neighborhood Hits	9
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

MEF2B_MOUSE
NC score	0.026818 (rank : 259)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	233	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

NCOA6_HUMAN
NC score	0.026434 (rank : 260)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	233	Target Neighborhood Hits	1202	Shared Neighborhood Hits	65
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MARCO_MOUSE
NC score	0.026110 (rank : 261)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	233	Target Neighborhood Hits	242	Shared Neighborhood Hits	22
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

LARP4_MOUSE
NC score	0.025809 (rank : 262)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	233	Target Neighborhood Hits	260	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

IF4B_MOUSE
NC score	0.025763 (rank : 263)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	233	Target Neighborhood Hits	368	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CBP_MOUSE
NC score	0.025757 (rank : 264)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	233	Target Neighborhood Hits	1051	Shared Neighborhood Hits	52
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NUP53_HUMAN
NC score	0.025649 (rank : 265)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	233	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

NRX2B_HUMAN
NC score	0.023442 (rank : 266)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	233	Target Neighborhood Hits	481	Shared Neighborhood Hits	34
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CTND2_HUMAN
NC score	0.022715 (rank : 267)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	233	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

EFS_MOUSE
NC score	0.022431 (rank : 268)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	233	Target Neighborhood Hits	389	Shared Neighborhood Hits	30
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

PGCA_HUMAN
NC score	0.022393 (rank : 269)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	233	Target Neighborhood Hits	821	Shared Neighborhood Hits	41
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LARP4_HUMAN
NC score	0.021754 (rank : 270)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	233	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

DICER_MOUSE
NC score	0.021299 (rank : 271)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	233	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

IWS1_MOUSE
NC score	0.019403 (rank : 272)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	233	Target Neighborhood Hits	1258	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DACH1_HUMAN
NC score	0.019260 (rank : 273)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	233	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

FOXN1_HUMAN
NC score	0.019011 (rank : 274)	θ value	0.47712 (rank : 112)
Query Neighborhood Hits	233	Target Neighborhood Hits	377	Shared Neighborhood Hits	23
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

TACC2_MOUSE
NC score	0.018899 (rank : 275)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	233	Target Neighborhood Hits	774	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

NIPBL_HUMAN
NC score	0.018422 (rank : 276)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	233	Target Neighborhood Hits	1311	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

BIM_HUMAN
NC score	0.018161 (rank : 277)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

IF4B_HUMAN
NC score	0.017911 (rank : 278)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	233	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MAST4_HUMAN
NC score	0.017557 (rank : 279)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	233	Target Neighborhood Hits	1804	Shared Neighborhood Hits	125
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PTN22_MOUSE
NC score	0.017353 (rank : 280)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	233	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

GA2L2_MOUSE
NC score	0.016974 (rank : 281)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	233	Target Neighborhood Hits	395	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

CSPG5_MOUSE
NC score	0.016806 (rank : 282)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	233	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

IASPP_MOUSE
NC score	0.016340 (rank : 283)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	233	Target Neighborhood Hits	1024	Shared Neighborhood Hits	53
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUMBL_MOUSE
NC score	0.015891 (rank : 284)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	233	Target Neighborhood Hits	147	Shared Neighborhood Hits	12
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

NRX2A_HUMAN
NC score	0.014841 (rank : 285)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	233	Target Neighborhood Hits	614	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

FBX41_HUMAN
NC score	0.014567 (rank : 286)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	233	Target Neighborhood Hits	475	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

RIMB1_MOUSE
NC score	0.014403 (rank : 287)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	233	Target Neighborhood Hits	1376	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ATG9A_HUMAN
NC score	0.014279 (rank : 288)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	233	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z3C6, Q6P0N7, Q7Z317, Q7Z320, Q8NDK6, Q8WU65, Q9BVL5, Q9H6L1, Q9HAG7	Gene names	ATG9A, APG9L1
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 9A (APG9-like 1).

RASF4_HUMAN
NC score	0.014247 (rank : 289)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	233	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2L5, Q86WH5, Q86WH6, Q86WH7, Q8N5A9, Q8TCK6	Gene names	RASSF4
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 4.

CFAB_HUMAN
NC score	0.014170 (rank : 290)	θ value	0.279714 (rank : 104)
Query Neighborhood Hits	233	Target Neighborhood Hits	251	Shared Neighborhood Hits	5
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

RP3A_MOUSE
NC score	0.013591 (rank : 291)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	233	Target Neighborhood Hits	510	Shared Neighborhood Hits	39
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SOX15_HUMAN
NC score	0.012510 (rank : 292)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	233	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

ANK2_HUMAN
NC score	0.011754 (rank : 293)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	233	Target Neighborhood Hits	1615	Shared Neighborhood Hits	55
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CCD45_MOUSE
NC score	0.011187 (rank : 294)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	233	Target Neighborhood Hits	663	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CAC1H_HUMAN
NC score	0.010958 (rank : 295)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	233	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

FGD1_MOUSE
NC score	0.010176 (rank : 296)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	233	Target Neighborhood Hits	387	Shared Neighborhood Hits	37
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MEFV_HUMAN
NC score	0.009542 (rank : 297)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	233	Target Neighborhood Hits	431	Shared Neighborhood Hits	17
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TXLNA_MOUSE
NC score	0.009539 (rank : 298)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	233	Target Neighborhood Hits	846	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

MYO15_MOUSE
NC score	0.007758 (rank : 299)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	233	Target Neighborhood Hits	467	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

UBP53_MOUSE
NC score	0.007704 (rank : 300)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	233	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

SOX15_MOUSE
NC score	0.005854 (rank : 301)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	233	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

BAI2_HUMAN
NC score	0.002377 (rank : 302)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	233	Target Neighborhood Hits	332	Shared Neighborhood Hits	11
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

WNK1_HUMAN
NC score	0.001931 (rank : 303)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	233	Target Neighborhood Hits	1158	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

TITIN_HUMAN
NC score	0.001347 (rank : 304)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	233	Target Neighborhood Hits	2923	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WNK1_MOUSE
NC score	0.000530 (rank : 305)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	233	Target Neighborhood Hits	1179	Shared Neighborhood Hits	28
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

TAOK1_HUMAN
NC score	-0.003377 (rank : 306)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	233	Target Neighborhood Hits	1734	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

SP5_HUMAN
NC score	-0.003532 (rank : 307)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	233	Target Neighborhood Hits	832	Shared Neighborhood Hits	15
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.