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Network neighborhood for query Sequence : UBP53_MOUSE

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UBP53_MOUSE
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP53_HUMAN
θ value	0 (rank : 1)	NC score	0.944994 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP54_HUMAN
θ value	9.87422e-140 (rank : 3)	NC score	0.912108 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
θ value	2.19974e-139 (rank : 4)	NC score	0.912322 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

FILA_HUMAN
θ value	2.21117e-06 (rank : 5)	NC score	0.163075 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	685	Shared Neighborhood Hits	72
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DSPP_HUMAN
θ value	3.19293e-05 (rank : 6)	NC score	0.133681 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	645	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

UBP18_MOUSE
θ value	4.1701e-05 (rank : 7)	NC score	0.182274 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

SFRS4_HUMAN
θ value	0.00035302 (rank : 8)	NC score	0.104569 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	384	Shared Neighborhood Hits	33
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

ANR11_HUMAN
θ value	0.00102713 (rank : 9)	NC score	0.063374 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	1289	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

AFF4_MOUSE
θ value	0.00134147 (rank : 10)	NC score	0.098596 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	581	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

SFRS4_MOUSE
θ value	0.00134147 (rank : 11)	NC score	0.106053 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

REST_HUMAN
θ value	0.00175202 (rank : 12)	NC score	0.030355 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	1605	Shared Neighborhood Hits	44
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

HORN_MOUSE
θ value	0.00228821 (rank : 13)	NC score	0.109974 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	218	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

RBBP6_MOUSE
θ value	0.00228821 (rank : 14)	NC score	0.109409 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	1014	Shared Neighborhood Hits	67
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SFR12_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.107623 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	486	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

PPRB_MOUSE
θ value	0.00665767 (rank : 16)	NC score	0.099041 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	35
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

ANR12_HUMAN
θ value	0.0148317 (rank : 17)	NC score	0.054598 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	1081	Shared Neighborhood Hits	61
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

LEO1_MOUSE
θ value	0.0148317 (rank : 18)	NC score	0.090136 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	946	Shared Neighborhood Hits	76
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

UBP35_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.122501 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

HORN_HUMAN
θ value	0.0193708 (rank : 20)	NC score	0.107458 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

NKTR_MOUSE
θ value	0.0193708 (rank : 21)	NC score	0.067845 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	417	Shared Neighborhood Hits	56
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SFR12_HUMAN
θ value	0.0193708 (rank : 22)	NC score	0.091633 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	553	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFRS6_HUMAN
θ value	0.0193708 (rank : 23)	NC score	0.087201 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	247	Shared Neighborhood Hits	25
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

LAP2_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.019417 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	499	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

RFC1_MOUSE
θ value	0.0431538 (rank : 25)	NC score	0.059617 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	290	Shared Neighborhood Hits	24
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

PRP4B_MOUSE
θ value	0.0563607 (rank : 26)	NC score	0.021823 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	1040	Shared Neighborhood Hits	37
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TOPRS_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.072949 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

UBP36_HUMAN
θ value	0.0563607 (rank : 28)	NC score	0.086980 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	232	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

CSPG2_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.023056 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	681	Shared Neighborhood Hits	20
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

NACAM_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.048115 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	1866	Shared Neighborhood Hits	72
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PININ_MOUSE
θ value	0.0736092 (rank : 31)	NC score	0.069454 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

ATRX_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.059359 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	842	Shared Neighborhood Hits	58
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TGON2_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.104478 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	1037	Shared Neighborhood Hits	88
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

UBP18_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.102603 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

IL6RB_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.029514 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

UBP38_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.091165 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBPW_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.101868 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

CIR_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.072977 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CORO7_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.020074 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	315	Shared Neighborhood Hits	4
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

DSPP_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.105632 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FUSIP_HUMAN
θ value	0.163984 (rank : 41)	NC score	0.057252 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	O75494, O60572, Q96G09, Q96P17	Gene names	FUSIP1, TASR
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (40 kDa SR-repressor protein) (SRrp40) (Splicing factor SRp38).

FUSIP_MOUSE
θ value	0.163984 (rank : 42)	NC score	0.057252 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0U0, O70307, O88468, Q3TGW7, Q8CFZ1, Q9R0T9	Gene names	Fusip1, Nssr
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (Neural-specific SR protein) (Neural-salient serine/arginine-rich protein).

NOTC1_MOUSE
θ value	0.163984 (rank : 43)	NC score	0.015514 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	916	Shared Neighborhood Hits	15
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TCOF_HUMAN
θ value	0.163984 (rank : 44)	NC score	0.064711 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	543	Shared Neighborhood Hits	37
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

NCOR2_MOUSE
θ value	0.21417 (rank : 45)	NC score	0.053165 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	790	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PPRB_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.083422 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	311	Shared Neighborhood Hits	23
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

CYLC1_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.065539 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MD1L1_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.019613 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	1001	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

RPTN_MOUSE
θ value	0.279714 (rank : 49)	NC score	0.092237 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

BRCA1_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.035834 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	436	Shared Neighborhood Hits	23
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

GOGA1_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.021201 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	1222	Shared Neighborhood Hits	29
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

UBP22_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.086941 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	0.365318 (rank : 53)	NC score	0.087021 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

CCD55_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.091779 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	519	Shared Neighborhood Hits	66
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CD2L7_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.008117 (rank : 207)
Query Neighborhood Hits	188	Target Neighborhood Hits	1275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CU013_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.039538 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	405	Shared Neighborhood Hits	17
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

PININ_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.060121 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SRRM2_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.067213 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	1296	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MYT1_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.029414 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	475	Shared Neighborhood Hits	27
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NOTC1_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.014427 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	15
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

STK10_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.010016 (rank : 204)
Query Neighborhood Hits	188	Target Neighborhood Hits	1921	Shared Neighborhood Hits	48
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

NCOR2_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.047799 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	870	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NU153_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.047119 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	22
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

SFRS5_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.066861 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q13243, O14797, Q16662	Gene names	SFRS5, HRS, SRP40
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

ZC3H6_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.034495 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ACINU_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.060546 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

GLIS3_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.001182 (rank : 216)
Query Neighborhood Hits	188	Target Neighborhood Hits	758	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

ILF3_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.032557 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

PINX1_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.035040 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q96BK5, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2	Gene names	PINX1, LPTS
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (67-11-3 protein).

PSD3_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.019981 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

RAI1_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.033981 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

THOC2_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.059554 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	337	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TOPRS_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.056070 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

UBP38_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.078691 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

AP3B2_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.036278 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	246	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CENPU_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.035208 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	137	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

CHD9_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.024245 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

UBP47_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.062432 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	149	Shared Neighborhood Hits	23
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP49_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.063833 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

AF9_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.044264 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CEP35_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.042917 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	811	Shared Neighborhood Hits	39
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CF151_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.038780 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IEG0, Q5T339, Q5THM1, Q5THM2, Q96MK1	Gene names	C6orf151
Domain Architecture	No domain graphic available
Description	U11/U12 snRNP 48 kDa protein.

MINT_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.049949 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	1291	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NP1L3_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.029168 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

RAIN_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.026177 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RIN3_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.021882 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	15
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

UGGG2_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.020537 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

APC_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.027983 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	441	Shared Neighborhood Hits	25
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CABIN_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.037341 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	490	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CASZ1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.020860 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	473	Shared Neighborhood Hits	7
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CSKI2_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.018377 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	747	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GPTC8_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.064275 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	366	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRIN1_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.046829 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	681	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MUC1_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.038908 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	388	Shared Neighborhood Hits	25
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RSRC1_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.063455 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SETD2_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.034002 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	412	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMOO_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.022754 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	391	Shared Neighborhood Hits	23
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TMUB2_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.023413 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V209, Q8K0X0, Q91YQ0, Q9D8C5	Gene names	Tmub2
Domain Architecture	No domain graphic available
Description	Transmembrane and ubiquitin-like domain-containing protein 2.

AP3B1_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.034036 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	302	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

EP15_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.016659 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	1021	Shared Neighborhood Hits	25
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FXR2_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.014335 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

ICAM5_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.007250 (rank : 209)
Query Neighborhood Hits	188	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

LCOR_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.028997 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

PER3_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.020349 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	33
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SAM14_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.031053 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SCG1_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.043136 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	156	Shared Neighborhood Hits	15
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

SGIP1_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.026458 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM1_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.044142 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	966	Shared Neighborhood Hits	66
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYK_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.019454 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

TCF20_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.036562 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TDRD3_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.029731 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

UBP51_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.079815 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	162	Shared Neighborhood Hits	22
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

CMGA_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.035715 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

FGD5_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.011460 (rank : 200)
Query Neighborhood Hits	188	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FOXD1_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.004650 (rank : 212)
Query Neighborhood Hits	188	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q61345	Gene names	Foxd1, Fkhl8, Freac4, Hfhbf2
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4) (Brain factor 2) (HFH-BF-2).

IL6RB_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.022333 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

JHD2C_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.020666 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

OXR1_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.035188 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	282	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

SOS1_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.017344 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	281	Shared Neighborhood Hits	13
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

TRRAP_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.022526 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

TRRAP_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.022646 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

UBP47_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.059321 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

ARI1B_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.025702 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	567	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CASC3_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.034025 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

M3K4_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.000777 (rank : 217)
Query Neighborhood Hits	188	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

MUCDL_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.016583 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	461	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOA6_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.024835 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	50
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ODPX_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.013431 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKZ9	Gene names	Pdhx
Domain Architecture	No domain graphic available
Description	Pyruvate dehydrogenase protein X component, mitochondrial precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X).

PCLO_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.030433 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	2275	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RBBP6_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.096251 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	1135	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SMC3_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.018459 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	1186	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.018425 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	1187	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SOS2_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.016354 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	193	Shared Neighborhood Hits	9
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

TADBP_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.022184 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q13148, Q96DJ0	Gene names	TARDBP, TDP43
Domain Architecture
Description	TAR DNA-binding protein 43 (TDP-43).

UBP50_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.056164 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

WASL_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.024343 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.022608 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	339	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

XKR5_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.016660 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

ZO3_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.008596 (rank : 206)
Query Neighborhood Hits	188	Target Neighborhood Hits	224	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ACHA4_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.003818 (rank : 213)
Query Neighborhood Hits	188	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	O70174, Q8BHE9, Q8VI10, Q9ET51	Gene names	Chrna4, Acra4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

ATN1_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.024322 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	676	Shared Neighborhood Hits	34
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CHD6_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.020749 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	342	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CK5P2_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.017347 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	1151	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CN037_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.018114 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

CTTB2_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.017759 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	1061	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DEK_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.034335 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

ENL_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.048766 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HMBX1_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.011760 (rank : 198)
Query Neighborhood Hits	188	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NT76, Q3Y6P1, Q96GS5, Q9H701	Gene names	HMBOX1
Domain Architecture	No domain graphic available
Description	Homeobox-containing protein 1.

KLF17_HUMAN
θ value	6.88961 (rank : 149)	NC score	-0.000571 (rank : 218)
Query Neighborhood Hits	188	Target Neighborhood Hits	882	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

MUC2_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.022052 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NSBP1_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.041078 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	681	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RAIN_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.021345 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RSRC1_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.050551 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

RXINP_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.013185 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

SOX4_MOUSE
θ value	6.88961 (rank : 155)	NC score	0.005958 (rank : 211)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

TARA_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.075847 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	1626	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TR2_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.003607 (rank : 214)
Query Neighborhood Hits	188	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

UBP15_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.042490 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	92	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.042027 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

YLPM1_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.038267 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	670	Shared Neighborhood Hits	44
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ATS9_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.001500 (rank : 215)
Query Neighborhood Hits	188	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BORG1_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.009712 (rank : 205)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

CF151_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.027815 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D361, Q8BIU0, Q8BJ30, Q8CFF6, Q8VDQ5, Q9CSG3, Q9CVM5	Gene names
Domain Architecture	No domain graphic available
Description	U11/U12 snRNP 48 kDa protein.

CHD1_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.024620 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.021178 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CI079_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.026645 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	288	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CSKI1_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.015156 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	1031	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DVL2_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.007704 (rank : 208)
Query Neighborhood Hits	188	Target Neighborhood Hits	233	Shared Neighborhood Hits	9
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FANCM_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.011504 (rank : 199)
Query Neighborhood Hits	188	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

GOGA3_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.011441 (rank : 201)
Query Neighborhood Hits	188	Target Neighborhood Hits	1317	Shared Neighborhood Hits	32
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HIRP3_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.052069 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

IWS1_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.084795 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	1241	Shared Neighborhood Hits	91
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JARD2_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.023177 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

K1267_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.012979 (rank : 197)
Query Neighborhood Hits	188	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

LCOR_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.021714 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

MUC5B_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.017363 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	1020	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYO9B_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.006030 (rank : 210)
Query Neighborhood Hits	188	Target Neighborhood Hits	641	Shared Neighborhood Hits	35
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PKN2_HUMAN
θ value	8.99809 (rank : 178)	NC score	-0.000837 (rank : 219)
Query Neighborhood Hits	188	Target Neighborhood Hits	892	Shared Neighborhood Hits	8
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

RBM15_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.031298 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	309	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

RBMX2_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.030597 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	287	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

RPGF1_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.013751 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	13
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SAM14_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.024329 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SON_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.030875 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	957	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TIMD4_MOUSE
θ value	8.99809 (rank : 184)	NC score	0.010741 (rank : 202)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

TNC6B_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.047705 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	256	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TR150_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.052496 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	313	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

WWC1_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.010135 (rank : 203)
Query Neighborhood Hits	188	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

ZC3H6_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.027082 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

AFF4_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.067575 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	611	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ATRX_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.051274 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	682	Shared Neighborhood Hits	58
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCD55_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.070676 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CYLC2_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.056099 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	28
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DMP1_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.059253 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

ELOA1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.056795 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	388	Shared Neighborhood Hits	49
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

IWS1_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.066164 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	1258	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.081045 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NIPBL_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.092912 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	1311	Shared Neighborhood Hits	98
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NKTR_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.057353 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	658	Shared Neighborhood Hits	66
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NPBL_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.093964 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	1041	Shared Neighborhood Hits	93
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PPIG_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.054987 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	670	Shared Neighborhood Hits	64
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RPTN_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.073928 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	45
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RRBP1_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.053401 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	1650	Shared Neighborhood Hits	79
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SEMG1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.055044 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEMG2_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.069025 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	251	Shared Neighborhood Hits	32
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SFR11_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.058404 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFRIP_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.064707 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	530	Shared Neighborhood Hits	58
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFRS5_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.053832 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

SRRM2_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.055491 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	1470	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TR150_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.054966 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	468	Shared Neighborhood Hits	51
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TTC16_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.077736 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	417	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TXND2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.066436 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP12_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.050486 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP42_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.055540 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP44_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.053862 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP46_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.057406 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	18
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.057406 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	18
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP49_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.050238 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

YTDC1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.063681 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	458	Shared Neighborhood Hits	52
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZC313_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.050445 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	772	Shared Neighborhood Hits	58
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

Hits sorted by NC score

UBP53_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP53_HUMAN
NC score	0.944994 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP54_MOUSE
NC score	0.912322 (rank : 3)	θ value	2.19974e-139 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_HUMAN
NC score	0.912108 (rank : 4)	θ value	9.87422e-140 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP18_MOUSE
NC score	0.182274 (rank : 5)	θ value	4.1701e-05 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

FILA_HUMAN
NC score	0.163075 (rank : 6)	θ value	2.21117e-06 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	685	Shared Neighborhood Hits	72
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DSPP_HUMAN
NC score	0.133681 (rank : 7)	θ value	3.19293e-05 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	645	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

UBP35_HUMAN
NC score	0.122501 (rank : 8)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

HORN_MOUSE
NC score	0.109974 (rank : 9)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	218	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

RBBP6_MOUSE
NC score	0.109409 (rank : 10)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	1014	Shared Neighborhood Hits	67
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SFR12_MOUSE
NC score	0.107623 (rank : 11)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	486	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

HORN_HUMAN
NC score	0.107458 (rank : 12)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

SFRS4_MOUSE
NC score	0.106053 (rank : 13)	θ value	0.00134147 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

DSPP_MOUSE
NC score	0.105632 (rank : 14)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SFRS4_HUMAN
NC score	0.104569 (rank : 15)	θ value	0.00035302 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	384	Shared Neighborhood Hits	33
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

TGON2_HUMAN
NC score	0.104478 (rank : 16)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	1037	Shared Neighborhood Hits	88
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

UBP18_HUMAN
NC score	0.102603 (rank : 17)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBPW_MOUSE
NC score	0.101868 (rank : 18)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

PPRB_MOUSE
NC score	0.099041 (rank : 19)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	35
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

AFF4_MOUSE
NC score	0.098596 (rank : 20)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	581	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

RBBP6_HUMAN
NC score	0.096251 (rank : 21)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	1135	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NPBL_MOUSE
NC score	0.093964 (rank : 22)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	188	Target Neighborhood Hits	1041	Shared Neighborhood Hits	93
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.092912 (rank : 23)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	188	Target Neighborhood Hits	1311	Shared Neighborhood Hits	98
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RPTN_MOUSE
NC score	0.092237 (rank : 24)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CCD55_MOUSE
NC score	0.091779 (rank : 25)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	519	Shared Neighborhood Hits	66
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

SFR12_HUMAN
NC score	0.091633 (rank : 26)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	553	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

UBP38_MOUSE
NC score	0.091165 (rank : 27)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

LEO1_MOUSE
NC score	0.090136 (rank : 28)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	946	Shared Neighborhood Hits	76
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SFRS6_HUMAN
NC score	0.087201 (rank : 29)	θ value	0.0193708 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	247	Shared Neighborhood Hits	25
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

UBP22_MOUSE
NC score	0.087021 (rank : 30)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP36_HUMAN
NC score	0.086980 (rank : 31)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	232	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP22_HUMAN
NC score	0.086941 (rank : 32)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

IWS1_HUMAN
NC score	0.084795 (rank : 33)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	1241	Shared Neighborhood Hits	91
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PPRB_HUMAN
NC score	0.083422 (rank : 34)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	311	Shared Neighborhood Hits	23
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

LEO1_HUMAN
NC score	0.081045 (rank : 35)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

UBP51_HUMAN
NC score	0.079815 (rank : 36)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	162	Shared Neighborhood Hits	22
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP38_HUMAN
NC score	0.078691 (rank : 37)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

TTC16_HUMAN
NC score	0.077736 (rank : 38)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	188	Target Neighborhood Hits	417	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TARA_HUMAN
NC score	0.075847 (rank : 39)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	1626	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RPTN_HUMAN
NC score	0.073928 (rank : 40)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	45
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

CIR_MOUSE
NC score	0.072977 (rank : 41)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

TOPRS_HUMAN
NC score	0.072949 (rank : 42)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CCD55_HUMAN
NC score	0.070676 (rank : 43)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

PININ_MOUSE
NC score	0.069454 (rank : 44)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SEMG2_HUMAN
NC score	0.069025 (rank : 45)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	188	Target Neighborhood Hits	251	Shared Neighborhood Hits	32
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

NKTR_MOUSE
NC score	0.067845 (rank : 46)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	417	Shared Neighborhood Hits	56
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

AFF4_HUMAN
NC score	0.067575 (rank : 47)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	611	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

SRRM2_HUMAN
NC score	0.067213 (rank : 48)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	1296	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SFRS5_HUMAN
NC score	0.066861 (rank : 49)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q13243, O14797, Q16662	Gene names	SFRS5, HRS, SRP40
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

TXND2_MOUSE
NC score	0.066436 (rank : 50)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	188	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

IWS1_MOUSE
NC score	0.066164 (rank : 51)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	1258	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CYLC1_HUMAN
NC score	0.065539 (rank : 52)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TCOF_HUMAN
NC score	0.064711 (rank : 53)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	543	Shared Neighborhood Hits	37
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SFRIP_HUMAN
NC score	0.064707 (rank : 54)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	188	Target Neighborhood Hits	530	Shared Neighborhood Hits	58
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

GPTC8_HUMAN
NC score	0.064275 (rank : 55)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	366	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

UBP49_MOUSE
NC score	0.063833 (rank : 56)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

YTDC1_HUMAN
NC score	0.063681 (rank : 57)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	188	Target Neighborhood Hits	458	Shared Neighborhood Hits	52
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

RSRC1_HUMAN
NC score	0.063455 (rank : 58)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

ANR11_HUMAN
NC score	0.063374 (rank : 59)	θ value	0.00102713 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	1289	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

UBP47_HUMAN
NC score	0.062432 (rank : 60)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	149	Shared Neighborhood Hits	23
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

ACINU_HUMAN
NC score	0.060546 (rank : 61)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PININ_HUMAN
NC score	0.060121 (rank : 62)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RFC1_MOUSE
NC score	0.059617 (rank : 63)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	290	Shared Neighborhood Hits	24
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

THOC2_HUMAN
NC score	0.059554 (rank : 64)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	337	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ATRX_HUMAN
NC score	0.059359 (rank : 65)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	842	Shared Neighborhood Hits	58
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

UBP47_MOUSE
NC score	0.059321 (rank : 66)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

DMP1_HUMAN
NC score	0.059253 (rank : 67)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

SFR11_HUMAN
NC score	0.058404 (rank : 68)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	188	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

UBP46_HUMAN
NC score	0.057406 (rank : 69)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	18
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.057406 (rank : 70)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	18
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

NKTR_HUMAN
NC score	0.057353 (rank : 71)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	188	Target Neighborhood Hits	658	Shared Neighborhood Hits	66
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

FUSIP_HUMAN
NC score	0.057252 (rank : 72)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	O75494, O60572, Q96G09, Q96P17	Gene names	FUSIP1, TASR
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (40 kDa SR-repressor protein) (SRrp40) (Splicing factor SRp38).

FUSIP_MOUSE
NC score	0.057252 (rank : 73)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0U0, O70307, O88468, Q3TGW7, Q8CFZ1, Q9R0T9	Gene names	Fusip1, Nssr
Domain Architecture
Description	FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (Neural-specific SR protein) (Neural-salient serine/arginine-rich protein).

ELOA1_HUMAN
NC score	0.056795 (rank : 74)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	388	Shared Neighborhood Hits	49
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

UBP50_MOUSE
NC score	0.056164 (rank : 75)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

CYLC2_HUMAN
NC score	0.056099 (rank : 76)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	28
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

TOPRS_MOUSE
NC score	0.056070 (rank : 77)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

UBP42_HUMAN
NC score	0.055540 (rank : 78)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

SRRM2_MOUSE
NC score	0.055491 (rank : 79)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	188	Target Neighborhood Hits	1470	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SEMG1_HUMAN
NC score	0.055044 (rank : 80)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	188	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

PPIG_HUMAN
NC score	0.054987 (rank : 81)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	188	Target Neighborhood Hits	670	Shared Neighborhood Hits	64
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TR150_MOUSE
NC score	0.054966 (rank : 82)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	188	Target Neighborhood Hits	468	Shared Neighborhood Hits	51
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ANR12_HUMAN
NC score	0.054598 (rank : 83)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	1081	Shared Neighborhood Hits	61
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

UBP44_HUMAN
NC score	0.053862 (rank : 84)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

SFRS5_MOUSE
NC score	0.053832 (rank : 85)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	188	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

RRBP1_MOUSE
NC score	0.053401 (rank : 86)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	188	Target Neighborhood Hits	1650	Shared Neighborhood Hits	79
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NCOR2_MOUSE
NC score	0.053165 (rank : 87)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	790	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

TR150_HUMAN
NC score	0.052496 (rank : 88)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	313	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

HIRP3_HUMAN
NC score	0.052069 (rank : 89)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

ATRX_MOUSE
NC score	0.051274 (rank : 90)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	682	Shared Neighborhood Hits	58
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

RSRC1_MOUSE
NC score	0.050551 (rank : 91)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

UBP12_HUMAN
NC score	0.050486 (rank : 92)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

ZC313_HUMAN
NC score	0.050445 (rank : 93)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	188	Target Neighborhood Hits	772	Shared Neighborhood Hits	58
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

UBP49_HUMAN
NC score	0.050238 (rank : 94)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

MINT_HUMAN
NC score	0.049949 (rank : 95)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	1291	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ENL_HUMAN
NC score	0.048766 (rank : 96)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

NACAM_MOUSE
NC score	0.048115 (rank : 97)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	1866	Shared Neighborhood Hits	72
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOR2_HUMAN
NC score	0.047799 (rank : 98)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	870	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TNC6B_HUMAN
NC score	0.047705 (rank : 99)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	256	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

NU153_HUMAN
NC score	0.047119 (rank : 100)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	22
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

GRIN1_HUMAN
NC score	0.046829 (rank : 101)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	681	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

AF9_HUMAN
NC score	0.044264 (rank : 102)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

SRRM1_MOUSE
NC score	0.044142 (rank : 103)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	966	Shared Neighborhood Hits	66
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SCG1_HUMAN
NC score	0.043136 (rank : 104)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	156	Shared Neighborhood Hits	15
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

CEP35_HUMAN
NC score	0.042917 (rank : 105)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	811	Shared Neighborhood Hits	39
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

UBP15_HUMAN
NC score	0.042490 (rank : 106)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	92	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
NC score	0.042027 (rank : 107)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

NSBP1_MOUSE
NC score	0.041078 (rank : 108)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	681	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

CU013_HUMAN
NC score	0.039538 (rank : 109)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	405	Shared Neighborhood Hits	17
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

MUC1_MOUSE
NC score	0.038908 (rank : 110)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	388	Shared Neighborhood Hits	25
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CF151_HUMAN
NC score	0.038780 (rank : 111)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IEG0, Q5T339, Q5THM1, Q5THM2, Q96MK1	Gene names	C6orf151
Domain Architecture	No domain graphic available
Description	U11/U12 snRNP 48 kDa protein.

YLPM1_HUMAN
NC score	0.038267 (rank : 112)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	670	Shared Neighborhood Hits	44
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CABIN_HUMAN
NC score	0.037341 (rank : 113)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	490	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

TCF20_HUMAN
NC score	0.036562 (rank : 114)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

AP3B2_MOUSE
NC score	0.036278 (rank : 115)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	246	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

BRCA1_MOUSE
NC score	0.035834 (rank : 116)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	436	Shared Neighborhood Hits	23
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CMGA_MOUSE
NC score	0.035715 (rank : 117)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

CENPU_MOUSE
NC score	0.035208 (rank : 118)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	137	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

OXR1_HUMAN
NC score	0.035188 (rank : 119)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	282	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

PINX1_HUMAN
NC score	0.035040 (rank : 120)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q96BK5, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2	Gene names	PINX1, LPTS
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (67-11-3 protein).

ZC3H6_MOUSE
NC score	0.034495 (rank : 121)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

DEK_MOUSE
NC score	0.034335 (rank : 122)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

AP3B1_MOUSE
NC score	0.034036 (rank : 123)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	302	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CASC3_MOUSE
NC score	0.034025 (rank : 124)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

SETD2_HUMAN
NC score	0.034002 (rank : 125)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	412	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

RAI1_HUMAN
NC score	0.033981 (rank : 126)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ILF3_MOUSE
NC score	0.032557 (rank : 127)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

RBM15_HUMAN
NC score	0.031298 (rank : 128)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	309	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

SAM14_HUMAN
NC score	0.031053 (rank : 129)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SON_MOUSE
NC score	0.030875 (rank : 130)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	957	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

RBMX2_MOUSE
NC score	0.030597 (rank : 131)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	287	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

PCLO_MOUSE
NC score	0.030433 (rank : 132)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	2275	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

REST_HUMAN
NC score	0.030355 (rank : 133)	θ value	0.00175202 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	1605	Shared Neighborhood Hits	44
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TDRD3_HUMAN
NC score	0.029731 (rank : 134)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

IL6RB_HUMAN
NC score	0.029514 (rank : 135)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

MYT1_HUMAN
NC score	0.029414 (rank : 136)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	475	Shared Neighborhood Hits	27
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NP1L3_MOUSE
NC score	0.029168 (rank : 137)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

LCOR_MOUSE
NC score	0.028997 (rank : 138)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

APC_MOUSE
NC score	0.027983 (rank : 139)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	441	Shared Neighborhood Hits	25
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CF151_MOUSE
NC score	0.027815 (rank : 140)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D361, Q8BIU0, Q8BJ30, Q8CFF6, Q8VDQ5, Q9CSG3, Q9CVM5	Gene names
Domain Architecture	No domain graphic available
Description	U11/U12 snRNP 48 kDa protein.

ZC3H6_HUMAN
NC score	0.027082 (rank : 141)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CI079_HUMAN
NC score	0.026645 (rank : 142)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	288	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

SGIP1_MOUSE
NC score	0.026458 (rank : 143)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

RAIN_HUMAN
NC score	0.026177 (rank : 144)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

ARI1B_HUMAN
NC score	0.025702 (rank : 145)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	567	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

NCOA6_HUMAN
NC score	0.024835 (rank : 146)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	50
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CHD1_HUMAN
NC score	0.024620 (rank : 147)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

WASL_HUMAN
NC score	0.024343 (rank : 148)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

SAM14_MOUSE
NC score	0.024329 (rank : 149)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

ATN1_HUMAN
NC score	0.024322 (rank : 150)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	676	Shared Neighborhood Hits	34
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CHD9_HUMAN
NC score	0.024245 (rank : 151)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

TMUB2_MOUSE
NC score	0.023413 (rank : 152)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V209, Q8K0X0, Q91YQ0, Q9D8C5	Gene names	Tmub2
Domain Architecture	No domain graphic available
Description	Transmembrane and ubiquitin-like domain-containing protein 2.

JARD2_HUMAN
NC score	0.023177 (rank : 153)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

CSPG2_HUMAN
NC score	0.023056 (rank : 154)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	681	Shared Neighborhood Hits	20
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

SMOO_HUMAN
NC score	0.022754 (rank : 155)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	391	Shared Neighborhood Hits	23
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TRRAP_MOUSE
NC score	0.022646 (rank : 156)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

WASL_MOUSE
NC score	0.022608 (rank : 157)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	339	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

TRRAP_HUMAN
NC score	0.022526 (rank : 158)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

IL6RB_MOUSE
NC score	0.022333 (rank : 159)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

TADBP_HUMAN
NC score	0.022184 (rank : 160)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q13148, Q96DJ0	Gene names	TARDBP, TDP43
Domain Architecture
Description	TAR DNA-binding protein 43 (TDP-43).

MUC2_HUMAN
NC score	0.022052 (rank : 161)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RIN3_MOUSE
NC score	0.021882 (rank : 162)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	15
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

PRP4B_MOUSE
NC score	0.021823 (rank : 163)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	1040	Shared Neighborhood Hits	37
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

LCOR_HUMAN
NC score	0.021714 (rank : 164)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

RAIN_MOUSE
NC score	0.021345 (rank : 165)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U0S6, Q6GQW4	Gene names	Rasip1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

GOGA1_HUMAN
NC score	0.021201 (rank : 166)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	1222	Shared Neighborhood Hits	29
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CHD2_HUMAN
NC score	0.021178 (rank : 167)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CASZ1_HUMAN
NC score	0.020860 (rank : 168)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	473	Shared Neighborhood Hits	7
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CHD6_HUMAN
NC score	0.020749 (rank : 169)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	342	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

JHD2C_HUMAN
NC score	0.020666 (rank : 170)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

UGGG2_HUMAN
NC score	0.020537 (rank : 171)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

PER3_HUMAN
NC score	0.020349 (rank : 172)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	33
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CORO7_HUMAN
NC score	0.020074 (rank : 173)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	315	Shared Neighborhood Hits	4
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

PSD3_HUMAN
NC score	0.019981 (rank : 174)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

MD1L1_MOUSE
NC score	0.019613 (rank : 175)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	1001	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

SYK_MOUSE
NC score	0.019454 (rank : 176)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

LAP2_HUMAN
NC score	0.019417 (rank : 177)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	499	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SMC3_HUMAN
NC score	0.018459 (rank : 178)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	1186	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
NC score	0.018425 (rank : 179)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	1187	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

CSKI2_HUMAN
NC score	0.018377 (rank : 180)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	747	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CN037_HUMAN
NC score	0.018114 (rank : 181)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

CTTB2_HUMAN
NC score	0.017759 (rank : 182)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	1061	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

MUC5B_HUMAN
NC score	0.017363 (rank : 183)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	1020	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CK5P2_MOUSE
NC score	0.017347 (rank : 184)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	1151	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

SOS1_MOUSE
NC score	0.017344 (rank : 185)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	281	Shared Neighborhood Hits	13
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

XKR5_HUMAN
NC score	0.016660 (rank : 186)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

EP15_HUMAN
NC score	0.016659 (rank : 187)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	1021	Shared Neighborhood Hits	25
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MUCDL_MOUSE
NC score	0.016583 (rank : 188)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	461	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SOS2_HUMAN
NC score	0.016354 (rank : 189)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	193	Shared Neighborhood Hits	9
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

NOTC1_MOUSE
NC score	0.015514 (rank : 190)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	916	Shared Neighborhood Hits	15
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CSKI1_MOUSE
NC score	0.015156 (rank : 191)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	1031	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NOTC1_HUMAN
NC score	0.014427 (rank : 192)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	15
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FXR2_HUMAN
NC score	0.014335 (rank : 193)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

RPGF1_HUMAN
NC score	0.013751 (rank : 194)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	13
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

ODPX_MOUSE
NC score	0.013431 (rank : 195)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKZ9	Gene names	Pdhx
Domain Architecture	No domain graphic available
Description	Pyruvate dehydrogenase protein X component, mitochondrial precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X).

RXINP_HUMAN
NC score	0.013185 (rank : 196)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

K1267_HUMAN
NC score	0.012979 (rank : 197)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

HMBX1_HUMAN
NC score	0.011760 (rank : 198)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NT76, Q3Y6P1, Q96GS5, Q9H701	Gene names	HMBOX1
Domain Architecture	No domain graphic available
Description	Homeobox-containing protein 1.

FANCM_MOUSE
NC score	0.011504 (rank : 199)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

FGD5_HUMAN
NC score	0.011460 (rank : 200)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

GOGA3_HUMAN
NC score	0.011441 (rank : 201)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	1317	Shared Neighborhood Hits	32
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

TIMD4_MOUSE
NC score	0.010741 (rank : 202)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

WWC1_HUMAN
NC score	0.010135 (rank : 203)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

STK10_HUMAN
NC score	0.010016 (rank : 204)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	1921	Shared Neighborhood Hits	48
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BORG1_HUMAN
NC score	0.009712 (rank : 205)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

ZO3_MOUSE
NC score	0.008596 (rank : 206)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	224	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

CD2L7_HUMAN
NC score	0.008117 (rank : 207)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	1275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

DVL2_MOUSE
NC score	0.007704 (rank : 208)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	233	Shared Neighborhood Hits	9
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

ICAM5_HUMAN
NC score	0.007250 (rank : 209)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

MYO9B_HUMAN
NC score	0.006030 (rank : 210)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	641	Shared Neighborhood Hits	35
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SOX4_MOUSE
NC score	0.005958 (rank : 211)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

FOXD1_MOUSE
NC score	0.004650 (rank : 212)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q61345	Gene names	Foxd1, Fkhl8, Freac4, Hfhbf2
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4) (Brain factor 2) (HFH-BF-2).

ACHA4_MOUSE
NC score	0.003818 (rank : 213)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	O70174, Q8BHE9, Q8VI10, Q9ET51	Gene names	Chrna4, Acra4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

TR2_HUMAN
NC score	0.003607 (rank : 214)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

ATS9_HUMAN
NC score	0.001500 (rank : 215)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

GLIS3_HUMAN
NC score	0.001182 (rank : 216)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	758	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

M3K4_HUMAN
NC score	0.000777 (rank : 217)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

KLF17_HUMAN
NC score	-0.000571 (rank : 218)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	882	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

PKN2_HUMAN
NC score	-0.000837 (rank : 219)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	892	Shared Neighborhood Hits	8
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).