Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RPGF1_HUMAN

For an explanation of this page, click here

RPGF1_HUMAN
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RPGF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	262	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

GNRP_HUMAN
θ value	1.24399e-33 (rank : 2)	NC score	0.653143 (rank : 19)
Query Neighborhood Hits	262	Target Neighborhood Hits	239	Shared Neighborhood Hits	24
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

SOS1_MOUSE
θ value	1.98606e-31 (rank : 3)	NC score	0.669574 (rank : 13)
Query Neighborhood Hits	262	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

GNRP_MOUSE
θ value	1.28732e-30 (rank : 4)	NC score	0.638569 (rank : 20)
Query Neighborhood Hits	262	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

SOS1_HUMAN
θ value	1.6813e-30 (rank : 5)	NC score	0.667976 (rank : 14)
Query Neighborhood Hits	262	Target Neighborhood Hits	274	Shared Neighborhood Hits	37
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS2_HUMAN
θ value	2.86786e-30 (rank : 6)	NC score	0.694201 (rank : 8)
Query Neighborhood Hits	262	Target Neighborhood Hits	193	Shared Neighborhood Hits	30
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

RPGF4_HUMAN
θ value	5.97985e-28 (rank : 7)	NC score	0.708195 (rank : 5)
Query Neighborhood Hits	262	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	2.96777e-27 (rank : 8)	NC score	0.704876 (rank : 6)
Query Neighborhood Hits	262	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RPGF5_MOUSE
θ value	5.23862e-24 (rank : 9)	NC score	0.743255 (rank : 3)
Query Neighborhood Hits	262	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF5_HUMAN
θ value	2.59989e-23 (rank : 10)	NC score	0.756449 (rank : 2)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q92565, Q8IXU5	Gene names	RAPGEF5, GFR, KIAA0277, MRGEF
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF3_HUMAN
θ value	3.39556e-23 (rank : 11)	NC score	0.680585 (rank : 11)
Query Neighborhood Hits	262	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

RPGF3_MOUSE
θ value	6.40375e-22 (rank : 12)	NC score	0.655439 (rank : 18)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

RPGF2_HUMAN
θ value	8.36355e-22 (rank : 13)	NC score	0.665492 (rank : 15)
Query Neighborhood Hits	262	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

GRP3_HUMAN
θ value	1.09232e-21 (rank : 14)	NC score	0.598054 (rank : 22)
Query Neighborhood Hits	262	Target Neighborhood Hits	131	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

RPGF6_HUMAN
θ value	1.2077e-20 (rank : 15)	NC score	0.638471 (rank : 21)
Query Neighborhood Hits	262	Target Neighborhood Hits	266	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

RGDSR_HUMAN
θ value	1.92812e-18 (rank : 16)	NC score	0.657855 (rank : 17)
Query Neighborhood Hits	262	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

RGL1_HUMAN
θ value	1.92812e-18 (rank : 17)	NC score	0.713239 (rank : 4)
Query Neighborhood Hits	262	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZL6, Q9HBY3, Q9HBY4, Q9NZL5, Q9UG43, Q9Y2G6	Gene names	RGL1, KIAA0959, RGL
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

RGL1_MOUSE
θ value	3.28887e-18 (rank : 18)	NC score	0.695315 (rank : 7)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q60695	Gene names	Rgl1, Rgl
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

GNDS_MOUSE
θ value	5.60996e-18 (rank : 19)	NC score	0.678404 (rank : 12)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

RGL2_HUMAN
θ value	4.74913e-17 (rank : 20)	NC score	0.685229 (rank : 9)
Query Neighborhood Hits	262	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

GNDS_HUMAN
θ value	1.058e-16 (rank : 21)	NC score	0.665040 (rank : 16)
Query Neighborhood Hits	262	Target Neighborhood Hits	201	Shared Neighborhood Hits	36
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

RGL2_MOUSE
θ value	1.38178e-16 (rank : 22)	NC score	0.682880 (rank : 10)
Query Neighborhood Hits	262	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RBM12_MOUSE
θ value	0.0113563 (rank : 23)	NC score	0.068189 (rank : 43)
Query Neighborhood Hits	262	Target Neighborhood Hits	313	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

FHOD1_HUMAN
θ value	0.0193708 (rank : 24)	NC score	0.099166 (rank : 25)
Query Neighborhood Hits	262	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FMN2_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.091205 (rank : 27)
Query Neighborhood Hits	262	Target Neighborhood Hits	349	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

DAAM1_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.072255 (rank : 39)
Query Neighborhood Hits	262	Target Neighborhood Hits	483	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

SNIP1_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.050889 (rank : 95)
Query Neighborhood Hits	262	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

AB1IP_MOUSE
θ value	0.125558 (rank : 28)	NC score	0.050638 (rank : 96)
Query Neighborhood Hits	262	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

BACH1_HUMAN
θ value	0.125558 (rank : 29)	NC score	0.018224 (rank : 216)
Query Neighborhood Hits	262	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

CO039_MOUSE
θ value	0.125558 (rank : 30)	NC score	0.066218 (rank : 46)
Query Neighborhood Hits	262	Target Neighborhood Hits	445	Shared Neighborhood Hits	66
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

PELP1_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.041470 (rank : 114)
Query Neighborhood Hits	262	Target Neighborhood Hits	596	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RAPH1_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.055864 (rank : 81)
Query Neighborhood Hits	262	Target Neighborhood Hits	593	Shared Neighborhood Hits	46
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RBM12_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.057772 (rank : 72)
Query Neighborhood Hits	262	Target Neighborhood Hits	298	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

ADIPO_MOUSE
θ value	0.21417 (rank : 34)	NC score	0.027911 (rank : 166)
Query Neighborhood Hits	262	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

MAGC2_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.016965 (rank : 221)
Query Neighborhood Hits	262	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBF1, Q5JZ00, Q96D45, Q9P1M6, Q9P1M7	Gene names	MAGEC2, HCA587, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen C2 (MAGE-C2 antigen) (MAGE-E1 antigen) (Hepatocellular carcinoma-associated antigen 587) (Cancer-testis antigen 10) (CT10).

PDC6I_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.035110 (rank : 133)
Query Neighborhood Hits	262	Target Neighborhood Hits	278	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PTN22_MOUSE
θ value	0.21417 (rank : 37)	NC score	0.018944 (rank : 213)
Query Neighborhood Hits	262	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

SH2D3_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.075600 (rank : 34)
Query Neighborhood Hits	262	Target Neighborhood Hits	188	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

HDAC6_MOUSE
θ value	0.279714 (rank : 39)	NC score	0.022312 (rank : 194)
Query Neighborhood Hits	262	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

CD2L7_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.006340 (rank : 277)
Query Neighborhood Hits	262	Target Neighborhood Hits	1275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

GLI2_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.005417 (rank : 281)
Query Neighborhood Hits	262	Target Neighborhood Hits	971	Shared Neighborhood Hits	42
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

CJ078_MOUSE
θ value	0.47712 (rank : 42)	NC score	0.046090 (rank : 106)
Query Neighborhood Hits	262	Target Neighborhood Hits	559	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

G3PT_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.039166 (rank : 119)
Query Neighborhood Hits	262	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

GGN_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.042157 (rank : 112)
Query Neighborhood Hits	262	Target Neighborhood Hits	269	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

ICA69_MOUSE
θ value	0.47712 (rank : 45)	NC score	0.034991 (rank : 135)
Query Neighborhood Hits	262	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

SRRM2_MOUSE
θ value	0.47712 (rank : 46)	NC score	0.056003 (rank : 79)
Query Neighborhood Hits	262	Target Neighborhood Hits	1470	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

VINC_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.042519 (rank : 111)
Query Neighborhood Hits	262	Target Neighborhood Hits	145	Shared Neighborhood Hits	10
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.039056 (rank : 120)
Query Neighborhood Hits	262	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

WASL_MOUSE
θ value	0.47712 (rank : 49)	NC score	0.047856 (rank : 103)
Query Neighborhood Hits	262	Target Neighborhood Hits	339	Shared Neighborhood Hits	32
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BRD4_HUMAN
θ value	0.62314 (rank : 50)	NC score	0.033758 (rank : 142)
Query Neighborhood Hits	262	Target Neighborhood Hits	851	Shared Neighborhood Hits	46
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CCDC6_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.015657 (rank : 233)
Query Neighborhood Hits	262	Target Neighborhood Hits	723	Shared Neighborhood Hits	15
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

FMN2_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.078701 (rank : 32)
Query Neighborhood Hits	262	Target Neighborhood Hits	484	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HCN4_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.015561 (rank : 234)
Query Neighborhood Hits	262	Target Neighborhood Hits	284	Shared Neighborhood Hits	14
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

SPEG_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.006706 (rank : 275)
Query Neighborhood Hits	262	Target Neighborhood Hits	1762	Shared Neighborhood Hits	73
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM2_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.045907 (rank : 107)
Query Neighborhood Hits	262	Target Neighborhood Hits	1296	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TACC2_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.031066 (rank : 155)
Query Neighborhood Hits	262	Target Neighborhood Hits	856	Shared Neighborhood Hits	49
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

YLPM1_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.033314 (rank : 146)
Query Neighborhood Hits	262	Target Neighborhood Hits	505	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

BRD4_MOUSE
θ value	0.813845 (rank : 58)	NC score	0.036989 (rank : 129)
Query Neighborhood Hits	262	Target Neighborhood Hits	845	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CAP2_MOUSE
θ value	0.813845 (rank : 59)	NC score	0.033499 (rank : 145)
Query Neighborhood Hits	262	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYT6, Q80YU7, Q9D6L0	Gene names	Cap2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

CC059_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.044307 (rank : 109)
Query Neighborhood Hits	262	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYB1, Q86VD8	Gene names	C3orf59
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf59.

CLCN1_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.015806 (rank : 230)
Query Neighborhood Hits	262	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CO5A1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.034491 (rank : 139)
Query Neighborhood Hits	262	Target Neighborhood Hits	419	Shared Neighborhood Hits	35
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

FMN1A_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.080382 (rank : 29)
Query Neighborhood Hits	262	Target Neighborhood Hits	423	Shared Neighborhood Hits	42
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.081872 (rank : 28)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

MILK1_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.040153 (rank : 117)
Query Neighborhood Hits	262	Target Neighborhood Hits	788	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

OST4_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.014830 (rank : 239)
Query Neighborhood Hits	262	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

PCGF6_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.023174 (rank : 186)
Query Neighborhood Hits	262	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

WASIP_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.049505 (rank : 101)
Query Neighborhood Hits	262	Target Neighborhood Hits	392	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ZO1_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.028513 (rank : 164)
Query Neighborhood Hits	262	Target Neighborhood Hits	453	Shared Neighborhood Hits	25
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DIAP1_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.058312 (rank : 68)
Query Neighborhood Hits	262	Target Neighborhood Hits	839	Shared Neighborhood Hits	41
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DIAP2_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.069222 (rank : 41)
Query Neighborhood Hits	262	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DYN2_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.014918 (rank : 238)
Query Neighborhood Hits	262	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

KCNN1_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.017672 (rank : 217)
Query Neighborhood Hits	262	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

PCLO_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.048421 (rank : 102)
Query Neighborhood Hits	262	Target Neighborhood Hits	2046	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SFRS8_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.038613 (rank : 124)
Query Neighborhood Hits	262	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SYN1_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.035760 (rank : 131)
Query Neighborhood Hits	262	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

ABTAP_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.026856 (rank : 169)
Query Neighborhood Hits	262	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AFF1_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.028749 (rank : 163)
Query Neighborhood Hits	262	Target Neighborhood Hits	351	Shared Neighborhood Hits	22
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

BAI1_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.007983 (rank : 267)
Query Neighborhood Hits	262	Target Neighborhood Hits	375	Shared Neighborhood Hits	19
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CO5A1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.033554 (rank : 144)
Query Neighborhood Hits	262	Target Neighborhood Hits	434	Shared Neighborhood Hits	36
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

ENL_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.033754 (rank : 143)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

S2A4R_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.037331 (rank : 127)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

SAPS1_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.051325 (rank : 92)
Query Neighborhood Hits	262	Target Neighborhood Hits	704	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SNP29_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.029779 (rank : 156)
Query Neighborhood Hits	262	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERB0, Q3UGN0, Q9DBC5	Gene names	Snap29
Domain Architecture
Description	Synaptosomal-associated protein 29 (SNAP-29) (Vesicle-membrane fusion protein SNAP-29) (Soluble 29 kDa NSF attachment protein) (Golgi SNARE of 32 kDa) (Gs32).

STAG3_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.016334 (rank : 226)
Query Neighborhood Hits	262	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

TACC2_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.036054 (rank : 130)
Query Neighborhood Hits	262	Target Neighborhood Hits	774	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WHRN_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.051725 (rank : 91)
Query Neighborhood Hits	262	Target Neighborhood Hits	412	Shared Neighborhood Hits	46
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WIRE_HUMAN
θ value	1.38821 (rank : 88)	NC score	0.051118 (rank : 93)
Query Neighborhood Hits	262	Target Neighborhood Hits	329	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.052230 (rank : 88)
Query Neighborhood Hits	262	Target Neighborhood Hits	310	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ABI2_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.034951 (rank : 136)
Query Neighborhood Hits	262	Target Neighborhood Hits	350	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.033895 (rank : 141)
Query Neighborhood Hits	262	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ACRO_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.003438 (rank : 291)
Query Neighborhood Hits	262	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ARHG1_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.017435 (rank : 219)
Query Neighborhood Hits	262	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARX_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.007740 (rank : 269)
Query Neighborhood Hits	262	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

CF015_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.042000 (rank : 113)
Query Neighborhood Hits	262	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

CO4A6_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.023605 (rank : 183)
Query Neighborhood Hits	262	Target Neighborhood Hits	318	Shared Neighborhood Hits	26
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

COIA1_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.028099 (rank : 165)
Query Neighborhood Hits	262	Target Neighborhood Hits	481	Shared Neighborhood Hits	46
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CT055_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.038305 (rank : 125)
Query Neighborhood Hits	262	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

DAAM2_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.064646 (rank : 52)
Query Neighborhood Hits	262	Target Neighborhood Hits	371	Shared Neighborhood Hits	24
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ENAH_MOUSE
θ value	1.81305 (rank : 100)	NC score	0.020975 (rank : 199)
Query Neighborhood Hits	262	Target Neighborhood Hits	919	Shared Neighborhood Hits	47
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GP1BA_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.009933 (rank : 255)
Query Neighborhood Hits	262	Target Neighborhood Hits	407	Shared Neighborhood Hits	16
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

KCNC3_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.011032 (rank : 250)
Query Neighborhood Hits	262	Target Neighborhood Hits	256	Shared Neighborhood Hits	23
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MDC1_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.057797 (rank : 71)
Query Neighborhood Hits	262	Target Neighborhood Hits	998	Shared Neighborhood Hits	100
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MTSS1_MOUSE
θ value	1.81305 (rank : 104)	NC score	0.047580 (rank : 104)
Query Neighborhood Hits	262	Target Neighborhood Hits	592	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PCQAP_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.025561 (rank : 176)
Query Neighborhood Hits	262	Target Neighborhood Hits	506	Shared Neighborhood Hits	22
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SNX14_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.031173 (rank : 154)
Query Neighborhood Hits	262	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SNX14_MOUSE
θ value	1.81305 (rank : 107)	NC score	0.032118 (rank : 149)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

TITIN_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.003688 (rank : 290)
Query Neighborhood Hits	262	Target Neighborhood Hits	2923	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WASF3_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.021227 (rank : 198)
Query Neighborhood Hits	262	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASP_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.038668 (rank : 123)
Query Neighborhood Hits	262	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZIM10_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.037180 (rank : 128)
Query Neighborhood Hits	262	Target Neighborhood Hits	430	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN598_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.022790 (rank : 189)
Query Neighborhood Hits	262	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ABI1_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.034504 (rank : 138)
Query Neighborhood Hits	262	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.034111 (rank : 140)
Query Neighborhood Hits	262	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABL2_HUMAN
θ value	2.36792 (rank : 115)	NC score	-0.000703 (rank : 303)
Query Neighborhood Hits	262	Target Neighborhood Hits	1045	Shared Neighborhood Hits	20
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ADDA_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.018458 (rank : 215)
Query Neighborhood Hits	262	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

AFF3_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.024829 (rank : 178)
Query Neighborhood Hits	262	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

CAP2_HUMAN
θ value	2.36792 (rank : 118)	NC score	0.029349 (rank : 159)
Query Neighborhood Hits	262	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P40123, Q6IAY2	Gene names	CAP2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

CC059_MOUSE
θ value	2.36792 (rank : 119)	NC score	0.038905 (rank : 121)
Query Neighborhood Hits	262	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C525, Q5U4H4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf59 homolog.

CDT1_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.026331 (rank : 173)
Query Neighborhood Hits	262	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

COBA2_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.027749 (rank : 167)
Query Neighborhood Hits	262	Target Neighborhood Hits	408	Shared Neighborhood Hits	33
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

DOC2B_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.009110 (rank : 262)
Query Neighborhood Hits	262	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

FHOD1_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.080120 (rank : 30)
Query Neighborhood Hits	262	Target Neighborhood Hits	217	Shared Neighborhood Hits	37
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FMNL_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.065013 (rank : 51)
Query Neighborhood Hits	262	Target Neighborhood Hits	529	Shared Neighborhood Hits	38
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

G3PT_HUMAN
θ value	2.36792 (rank : 125)	NC score	0.031527 (rank : 152)
Query Neighborhood Hits	262	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

KCNQ4_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.014920 (rank : 237)
Query Neighborhood Hits	262	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

MN1_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.029729 (rank : 157)
Query Neighborhood Hits	262	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

NPBL_MOUSE
θ value	2.36792 (rank : 128)	NC score	0.026918 (rank : 168)
Query Neighborhood Hits	262	Target Neighborhood Hits	1041	Shared Neighborhood Hits	59
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PHLB1_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.022806 (rank : 188)
Query Neighborhood Hits	262	Target Neighborhood Hits	678	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA6_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.040530 (rank : 116)
Query Neighborhood Hits	262	Target Neighborhood Hits	591	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PRDM2_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.007437 (rank : 271)
Query Neighborhood Hits	262	Target Neighborhood Hits	1135	Shared Neighborhood Hits	40
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SATB1_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.016805 (rank : 224)
Query Neighborhood Hits	262	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SMCA4_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.014532 (rank : 241)
Query Neighborhood Hits	262	Target Neighborhood Hits	597	Shared Neighborhood Hits	35
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SN1L2_HUMAN
θ value	2.36792 (rank : 134)	NC score	-0.000192 (rank : 302)
Query Neighborhood Hits	262	Target Neighborhood Hits	964	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

ZN580_MOUSE
θ value	2.36792 (rank : 135)	NC score	0.000331 (rank : 300)
Query Neighborhood Hits	262	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

ZN750_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.024523 (rank : 180)
Query Neighborhood Hits	262	Target Neighborhood Hits	183	Shared Neighborhood Hits	15
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AFAD_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.037678 (rank : 126)
Query Neighborhood Hits	262	Target Neighborhood Hits	689	Shared Neighborhood Hits	29
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AIRE_HUMAN
θ value	3.0926 (rank : 138)	NC score	0.014947 (rank : 236)
Query Neighborhood Hits	262	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

CO1A1_MOUSE
θ value	3.0926 (rank : 139)	NC score	0.026418 (rank : 172)
Query Neighborhood Hits	262	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CREB5_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.019033 (rank : 212)
Query Neighborhood Hits	262	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

CSKI1_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.012705 (rank : 245)
Query Neighborhood Hits	262	Target Neighborhood Hits	997	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DIAP1_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.059104 (rank : 66)
Query Neighborhood Hits	262	Target Neighborhood Hits	784	Shared Neighborhood Hits	40
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP3_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.063887 (rank : 55)
Query Neighborhood Hits	262	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DLGP4_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.015710 (rank : 231)
Query Neighborhood Hits	262	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

EMIL2_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.020333 (rank : 203)
Query Neighborhood Hits	262	Target Neighborhood Hits	485	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

HCLS1_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.035107 (rank : 134)
Query Neighborhood Hits	262	Target Neighborhood Hits	358	Shared Neighborhood Hits	56
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

K1849_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.034866 (rank : 137)
Query Neighborhood Hits	262	Target Neighborhood Hits	335	Shared Neighborhood Hits	34
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MTF1_MOUSE
θ value	3.0926 (rank : 148)	NC score	-0.001129 (rank : 305)
Query Neighborhood Hits	262	Target Neighborhood Hits	785	Shared Neighborhood Hits	17
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NFAC4_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.016333 (rank : 227)
Query Neighborhood Hits	262	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PCLO_MOUSE
θ value	3.0926 (rank : 150)	NC score	0.044058 (rank : 110)
Query Neighborhood Hits	262	Target Neighborhood Hits	2275	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYN2_HUMAN
θ value	3.0926 (rank : 151)	NC score	0.028960 (rank : 161)
Query Neighborhood Hits	262	Target Neighborhood Hits	213	Shared Neighborhood Hits	18
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TMM24_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.020144 (rank : 205)
Query Neighborhood Hits	262	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

TRI66_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.022667 (rank : 190)
Query Neighborhood Hits	262	Target Neighborhood Hits	479	Shared Neighborhood Hits	32
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WASIP_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.045424 (rank : 108)
Query Neighborhood Hits	262	Target Neighborhood Hits	458	Shared Neighborhood Hits	36
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASL_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.040963 (rank : 115)
Query Neighborhood Hits	262	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN219_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.001538 (rank : 297)
Query Neighborhood Hits	262	Target Neighborhood Hits	876	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ADA1B_MOUSE
θ value	4.03905 (rank : 157)	NC score	-0.004022 (rank : 310)
Query Neighborhood Hits	262	Target Neighborhood Hits	966	Shared Neighborhood Hits	6
SwissProt Accessions	P97717	Gene names	Adra1b
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

CD2L6_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.000704 (rank : 298)
Query Neighborhood Hits	262	Target Neighborhood Hits	851	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

DIAP2_MOUSE
θ value	4.03905 (rank : 159)	NC score	0.065482 (rank : 48)
Query Neighborhood Hits	262	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

FMNL_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.066050 (rank : 47)
Query Neighborhood Hits	262	Target Neighborhood Hits	428	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

HXA3_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.009231 (rank : 261)
Query Neighborhood Hits	262	Target Neighborhood Hits	558	Shared Neighborhood Hits	26
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXD3_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.006937 (rank : 273)
Query Neighborhood Hits	262	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

IGHE_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.006825 (rank : 274)
Query Neighborhood Hits	262	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	P06336, P01856	Gene names
Domain Architecture
Description	Ig epsilon chain C region.

MLL4_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.020541 (rank : 201)
Query Neighborhood Hits	262	Target Neighborhood Hits	722	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MORC2_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.016140 (rank : 229)
Query Neighborhood Hits	262	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

PTN12_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.009752 (rank : 257)
Query Neighborhood Hits	262	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

RFIP1_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.017100 (rank : 220)
Query Neighborhood Hits	262	Target Neighborhood Hits	152	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RORG_HUMAN
θ value	4.03905 (rank : 168)	NC score	0.004167 (rank : 287)
Query Neighborhood Hits	262	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

SQSTM_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.018855 (rank : 214)
Query Neighborhood Hits	262	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

ST5_MOUSE
θ value	4.03905 (rank : 170)	NC score	0.011370 (rank : 247)
Query Neighborhood Hits	262	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

TEX2_MOUSE
θ value	4.03905 (rank : 171)	NC score	0.016667 (rank : 225)
Query Neighborhood Hits	262	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TTC12_HUMAN
θ value	4.03905 (rank : 172)	NC score	0.011131 (rank : 249)
Query Neighborhood Hits	262	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

UBE4B_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.022522 (rank : 191)
Query Neighborhood Hits	262	Target Neighborhood Hits	158	Shared Neighborhood Hits	14
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ZIM10_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.047257 (rank : 105)
Query Neighborhood Hits	262	Target Neighborhood Hits	577	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ABI3_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.032026 (rank : 150)
Query Neighborhood Hits	262	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABRA_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.019893 (rank : 207)
Query Neighborhood Hits	262	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

ABTAP_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.022352 (rank : 193)
Query Neighborhood Hits	262	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AGRIN_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.002539 (rank : 295)
Query Neighborhood Hits	262	Target Neighborhood Hits	582	Shared Neighborhood Hits	13
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CCD93_MOUSE
θ value	5.27518 (rank : 179)	NC score	0.008223 (rank : 265)
Query Neighborhood Hits	262	Target Neighborhood Hits	362	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CS007_MOUSE
θ value	5.27518 (rank : 180)	NC score	0.026697 (rank : 170)
Query Neighborhood Hits	262	Target Neighborhood Hits	464	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.035232 (rank : 132)
Query Neighborhood Hits	262	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CT055_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.031480 (rank : 153)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

E2F2_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.009602 (rank : 259)
Query Neighborhood Hits	262	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

FNDC3_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.007862 (rank : 268)
Query Neighborhood Hits	262	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FZD8_MOUSE
θ value	5.27518 (rank : 185)	NC score	0.005142 (rank : 284)
Query Neighborhood Hits	262	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

IASPP_MOUSE
θ value	5.27518 (rank : 186)	NC score	0.031837 (rank : 151)
Query Neighborhood Hits	262	Target Neighborhood Hits	1024	Shared Neighborhood Hits	94
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K0460_MOUSE
θ value	5.27518 (rank : 187)	NC score	0.016203 (rank : 228)
Query Neighborhood Hits	262	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

M4K1_MOUSE
θ value	5.27518 (rank : 188)	NC score	-0.001195 (rank : 306)
Query Neighborhood Hits	262	Target Neighborhood Hits	858	Shared Neighborhood Hits	11
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

NKX24_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.006566 (rank : 276)
Query Neighborhood Hits	262	Target Neighborhood Hits	366	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

NU214_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.023738 (rank : 182)
Query Neighborhood Hits	262	Target Neighborhood Hits	657	Shared Neighborhood Hits	37
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PDCD7_MOUSE
θ value	5.27518 (rank : 191)	NC score	0.020197 (rank : 204)
Query Neighborhood Hits	262	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PHC2_HUMAN
θ value	5.27518 (rank : 192)	NC score	0.029397 (rank : 158)
Query Neighborhood Hits	262	Target Neighborhood Hits	388	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PK1L1_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.016831 (rank : 222)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RGS3_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.075511 (rank : 35)
Query Neighborhood Hits	262	Target Neighborhood Hits	1621	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SP5_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.000655 (rank : 299)
Query Neighborhood Hits	262	Target Neighborhood Hits	832	Shared Neighborhood Hits	33
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SRRM1_MOUSE
θ value	5.27518 (rank : 196)	NC score	0.039704 (rank : 118)
Query Neighborhood Hits	262	Target Neighborhood Hits	966	Shared Neighborhood Hits	77
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYN1_MOUSE
θ value	5.27518 (rank : 197)	NC score	0.028936 (rank : 162)
Query Neighborhood Hits	262	Target Neighborhood Hits	363	Shared Neighborhood Hits	30
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ABI3_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.032335 (rank : 148)
Query Neighborhood Hits	262	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

APBA1_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.010865 (rank : 252)
Query Neighborhood Hits	262	Target Neighborhood Hits	325	Shared Neighborhood Hits	23
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

ARX_MOUSE
θ value	6.88961 (rank : 200)	NC score	0.006065 (rank : 278)
Query Neighborhood Hits	262	Target Neighborhood Hits	398	Shared Neighborhood Hits	15
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

BRD3_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.020362 (rank : 202)
Query Neighborhood Hits	262	Target Neighborhood Hits	369	Shared Neighborhood Hits	17
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

C1QT5_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.022369 (rank : 192)
Query Neighborhood Hits	262	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

CNOT3_HUMAN
θ value	6.88961 (rank : 203)	NC score	0.014737 (rank : 240)
Query Neighborhood Hits	262	Target Neighborhood Hits	425	Shared Neighborhood Hits	21
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO9A1_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.020651 (rank : 200)
Query Neighborhood Hits	262	Target Neighborhood Hits	420	Shared Neighborhood Hits	33
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COBA1_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.026444 (rank : 171)
Query Neighborhood Hits	262	Target Neighborhood Hits	491	Shared Neighborhood Hits	34
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	6.88961 (rank : 206)	NC score	0.026274 (rank : 174)
Query Neighborhood Hits	262	Target Neighborhood Hits	487	Shared Neighborhood Hits	36
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CRTC1_HUMAN
θ value	6.88961 (rank : 207)	NC score	0.029233 (rank : 160)
Query Neighborhood Hits	262	Target Neighborhood Hits	319	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS007_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.023163 (rank : 187)
Query Neighborhood Hits	262	Target Neighborhood Hits	401	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CTCF_MOUSE
θ value	6.88961 (rank : 209)	NC score	-0.002898 (rank : 307)
Query Neighborhood Hits	262	Target Neighborhood Hits	796	Shared Neighborhood Hits	16
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

DAB2P_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.007707 (rank : 270)
Query Neighborhood Hits	262	Target Neighborhood Hits	303	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

FA54A_MOUSE
θ value	6.88961 (rank : 211)	NC score	0.013840 (rank : 242)
Query Neighborhood Hits	262	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VED8	Gene names	Fam54a, Dufd1
Domain Architecture	No domain graphic available
Description	Protein FAM54A (DUF729 domain-containing protein 1).

FIP1_MOUSE
θ value	6.88961 (rank : 212)	NC score	0.015246 (rank : 235)
Query Neighborhood Hits	262	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

ICA69_HUMAN
θ value	6.88961 (rank : 213)	NC score	0.024130 (rank : 181)
Query Neighborhood Hits	262	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q05084, P78506, Q13824	Gene names	ICA1
Domain Architecture
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

KCNQ2_HUMAN
θ value	6.88961 (rank : 214)	NC score	0.011173 (rank : 248)
Query Neighborhood Hits	262	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

LRRK2_HUMAN
θ value	6.88961 (rank : 215)	NC score	-0.003081 (rank : 308)
Query Neighborhood Hits	262	Target Neighborhood Hits	1382	Shared Neighborhood Hits	10
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

MEGF8_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.002008 (rank : 296)
Query Neighborhood Hits	262	Target Neighborhood Hits	528	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NACAM_MOUSE
θ value	6.88961 (rank : 217)	NC score	0.072406 (rank : 38)
Query Neighborhood Hits	262	Target Neighborhood Hits	1866	Shared Neighborhood Hits	153
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NOLC1_HUMAN
θ value	6.88961 (rank : 218)	NC score	0.025141 (rank : 177)
Query Neighborhood Hits	262	Target Neighborhood Hits	452	Shared Neighborhood Hits	20
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

RBCC1_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.002830 (rank : 294)
Query Neighborhood Hits	262	Target Neighborhood Hits	1048	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RERE_MOUSE
θ value	6.88961 (rank : 220)	NC score	0.019643 (rank : 209)
Query Neighborhood Hits	262	Target Neighborhood Hits	785	Shared Neighborhood Hits	49
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SET1A_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.019596 (rank : 210)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	37
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.019760 (rank : 208)
Query Neighborhood Hits	262	Target Neighborhood Hits	287	Shared Neighborhood Hits	20
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	6.88961 (rank : 223)	NC score	0.020128 (rank : 206)
Query Neighborhood Hits	262	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SHAN1_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.017585 (rank : 218)
Query Neighborhood Hits	262	Target Neighborhood Hits	1041	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMCA2_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.010937 (rank : 251)
Query Neighborhood Hits	262	Target Neighborhood Hits	503	Shared Neighborhood Hits	26
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ASPP1_MOUSE
θ value	8.99809 (rank : 226)	NC score	0.024766 (rank : 179)
Query Neighborhood Hits	262	Target Neighborhood Hits	1244	Shared Neighborhood Hits	101
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATRIP_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.009513 (rank : 260)
Query Neighborhood Hits	262	Target Neighborhood Hits	249	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

C1QT5_HUMAN
θ value	8.99809 (rank : 228)	NC score	0.022133 (rank : 196)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

CABC1_MOUSE
θ value	8.99809 (rank : 229)	NC score	0.009994 (rank : 253)
Query Neighborhood Hits	262	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q60936, Q8K0M1	Gene names	Cabc1
Domain Architecture
Description	Chaperone-activity of bc1 complex-like, mitochondrial precursor (Chaperone-ABC1-like).

CBX6_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.009010 (rank : 263)
Query Neighborhood Hits	262	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CCNK_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.015696 (rank : 232)
Query Neighborhood Hits	262	Target Neighborhood Hits	350	Shared Neighborhood Hits	26
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CO4A2_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.022268 (rank : 195)
Query Neighborhood Hits	262	Target Neighborhood Hits	454	Shared Neighborhood Hits	43
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COA1_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.007183 (rank : 272)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

EMBP_MOUSE
θ value	8.99809 (rank : 234)	NC score	0.008720 (rank : 264)
Query Neighborhood Hits	262	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

FBLI1_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.004503 (rank : 285)
Query Neighborhood Hits	262	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

FOXGB_MOUSE
θ value	8.99809 (rank : 236)	NC score	0.003079 (rank : 292)
Query Neighborhood Hits	262	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

FOXL2_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.002856 (rank : 293)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

GSCR1_HUMAN
θ value	8.99809 (rank : 238)	NC score	0.026265 (rank : 175)
Query Neighborhood Hits	262	Target Neighborhood Hits	674	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCLS1_MOUSE
θ value	8.99809 (rank : 239)	NC score	0.023418 (rank : 184)
Query Neighborhood Hits	262	Target Neighborhood Hits	329	Shared Neighborhood Hits	45
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HXA3_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.008153 (rank : 266)
Query Neighborhood Hits	262	Target Neighborhood Hits	535	Shared Neighborhood Hits	30
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

INSM1_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.000275 (rank : 301)
Query Neighborhood Hits	262	Target Neighborhood Hits	683	Shared Neighborhood Hits	11
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

JHD3B_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.005981 (rank : 279)
Query Neighborhood Hits	262	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

LATS1_MOUSE
θ value	8.99809 (rank : 243)	NC score	-0.001065 (rank : 304)
Query Neighborhood Hits	262	Target Neighborhood Hits	1027	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MBD6_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.021510 (rank : 197)
Query Neighborhood Hits	262	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

NFH_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.005372 (rank : 282)
Query Neighborhood Hits	262	Target Neighborhood Hits	1242	Shared Neighborhood Hits	40
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NFKB1_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.003972 (rank : 288)
Query Neighborhood Hits	262	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
θ value	8.99809 (rank : 247)	NC score	0.004213 (rank : 286)
Query Neighborhood Hits	262	Target Neighborhood Hits	300	Shared Neighborhood Hits	8
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NKX24_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.005837 (rank : 280)
Query Neighborhood Hits	262	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQM3, Q9EQM4	Gene names	Nkx2-4, Nkx2d
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

P85B_MOUSE
θ value	8.99809 (rank : 249)	NC score	0.005170 (rank : 283)
Query Neighborhood Hits	262	Target Neighborhood Hits	519	Shared Neighborhood Hits	12
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PRP2_MOUSE
θ value	8.99809 (rank : 250)	NC score	0.023190 (rank : 185)
Query Neighborhood Hits	262	Target Neighborhood Hits	347	Shared Neighborhood Hits	26
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RUSC1_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.011808 (rank : 246)
Query Neighborhood Hits	262	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SFR17_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.012761 (rank : 244)
Query Neighborhood Hits	262	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SGIP1_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.019596 (rank : 211)
Query Neighborhood Hits	262	Target Neighborhood Hits	180	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM1_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.038731 (rank : 122)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SYNE2_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.003953 (rank : 289)
Query Neighborhood Hits	262	Target Neighborhood Hits	1323	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SYNPO_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.032710 (rank : 147)
Query Neighborhood Hits	262	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TM16H_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.009925 (rank : 256)
Query Neighborhood Hits	262	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TREF1_HUMAN
θ value	8.99809 (rank : 258)	NC score	0.009970 (rank : 254)
Query Neighborhood Hits	262	Target Neighborhood Hits	651	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

TREF1_MOUSE
θ value	8.99809 (rank : 259)	NC score	0.009747 (rank : 258)
Query Neighborhood Hits	262	Target Neighborhood Hits	682	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

UBE4B_MOUSE
θ value	8.99809 (rank : 260)	NC score	0.016821 (rank : 223)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES00, Q9EQE0	Gene names	Ube4b, Ufd2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Ufd2a).

UBP53_MOUSE
θ value	8.99809 (rank : 261)	NC score	0.013751 (rank : 243)
Query Neighborhood Hits	262	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

ZN619_HUMAN
θ value	8.99809 (rank : 262)	NC score	-0.003921 (rank : 309)
Query Neighborhood Hits	262	Target Neighborhood Hits	749	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2I2	Gene names	ZNF619
Domain Architecture	No domain graphic available
Description	Zinc finger protein 619.

ARHG4_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.064614 (rank : 53)
Query Neighborhood Hits	262	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.056677 (rank : 75)
Query Neighborhood Hits	262	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG7_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.060851 (rank : 61)
Query Neighborhood Hits	262	Target Neighborhood Hits	347	Shared Neighborhood Hits	18
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.057060 (rank : 74)
Query Neighborhood Hits	262	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG9_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.063527 (rank : 56)
Query Neighborhood Hits	262	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.063891 (rank : 54)
Query Neighborhood Hits	262	Target Neighborhood Hits	234	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

BCL9_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.074310 (rank : 36)
Query Neighborhood Hits	262	Target Neighborhood Hits	1008	Shared Neighborhood Hits	132
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.053341 (rank : 86)
Query Neighborhood Hits	262	Target Neighborhood Hits	770	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CEL_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.051745 (rank : 90)
Query Neighborhood Hits	262	Target Neighborhood Hits	896	Shared Neighborhood Hits	126
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CT152_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.118030 (rank : 24)
Query Neighborhood Hits	262	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

CT152_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.096529 (rank : 26)
Query Neighborhood Hits	262	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

DAAM1_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.058082 (rank : 69)
Query Neighborhood Hits	262	Target Neighborhood Hits	443	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM2_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.061028 (rank : 60)
Query Neighborhood Hits	262	Target Neighborhood Hits	350	Shared Neighborhood Hits	27
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DIAP3_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.057933 (rank : 70)
Query Neighborhood Hits	262	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

ECT2_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.072878 (rank : 37)
Query Neighborhood Hits	262	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.069127 (rank : 42)
Query Neighborhood Hits	262	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FA47A_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.050565 (rank : 97)
Query Neighborhood Hits	262	Target Neighborhood Hits	451	Shared Neighborhood Hits	75
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.060542 (rank : 63)
Query Neighborhood Hits	262	Target Neighborhood Hits	431	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FGD1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.050138 (rank : 100)
Query Neighborhood Hits	262	Target Neighborhood Hits	367	Shared Neighborhood Hits	27
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.050481 (rank : 98)
Query Neighborhood Hits	262	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.056492 (rank : 76)
Query Neighborhood Hits	262	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD3_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.063179 (rank : 58)
Query Neighborhood Hits	262	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.056153 (rank : 77)
Query Neighborhood Hits	262	Target Neighborhood Hits	257	Shared Neighborhood Hits	13
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.060409 (rank : 64)
Query Neighborhood Hits	262	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.058643 (rank : 67)
Query Neighborhood Hits	262	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

GP155_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.060831 (rank : 62)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

KAP0_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.053781 (rank : 84)
Query Neighborhood Hits	262	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.053928 (rank : 83)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.065358 (rank : 49)
Query Neighborhood Hits	262	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.063361 (rank : 57)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.050942 (rank : 94)
Query Neighborhood Hits	262	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

MDC1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.056014 (rank : 78)
Query Neighborhood Hits	262	Target Neighborhood Hits	1446	Shared Neighborhood Hits	103
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL3_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.051896 (rank : 89)
Query Neighborhood Hits	262	Target Neighborhood Hits	1644	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUC1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.076249 (rank : 33)
Query Neighborhood Hits	262	Target Neighborhood Hits	975	Shared Neighborhood Hits	128
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.061835 (rank : 59)
Query Neighborhood Hits	262	Target Neighborhood Hits	1202	Shared Neighborhood Hits	127
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NGEF_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.065073 (rank : 50)
Query Neighborhood Hits	262	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.057571 (rank : 73)
Query Neighborhood Hits	262	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

OGFR_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.067776 (rank : 44)
Query Neighborhood Hits	262	Target Neighborhood Hits	1582	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PREX1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.132664 (rank : 23)
Query Neighborhood Hits	262	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRRT3_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.070479 (rank : 40)
Query Neighborhood Hits	262	Target Neighborhood Hits	998	Shared Neighborhood Hits	131
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS3_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.054450 (rank : 82)
Query Neighborhood Hits	262	Target Neighborhood Hits	1375	Shared Neighborhood Hits	145
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.067047 (rank : 45)
Query Neighborhood Hits	262	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SON_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.079415 (rank : 31)
Query Neighborhood Hits	262	Target Neighborhood Hits	1568	Shared Neighborhood Hits	149
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARSH_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.052480 (rank : 87)
Query Neighborhood Hits	262	Target Neighborhood Hits	768	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

VAV2_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.055923 (rank : 80)
Query Neighborhood Hits	262	Target Neighborhood Hits	453	Shared Neighborhood Hits	23
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.059161 (rank : 65)
Query Neighborhood Hits	262	Target Neighborhood Hits	456	Shared Neighborhood Hits	27
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.053674 (rank : 85)
Query Neighborhood Hits	262	Target Neighborhood Hits	404	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ZIMP7_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.050237 (rank : 99)
Query Neighborhood Hits	262	Target Neighborhood Hits	566	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

Hits sorted by NC score

RPGF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	262	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

RPGF5_HUMAN
NC score	0.756449 (rank : 2)	θ value	2.59989e-23 (rank : 10)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q92565, Q8IXU5	Gene names	RAPGEF5, GFR, KIAA0277, MRGEF
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF5_MOUSE
NC score	0.743255 (rank : 3)	θ value	5.23862e-24 (rank : 9)
Query Neighborhood Hits	262	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

RGL1_HUMAN
NC score	0.713239 (rank : 4)	θ value	1.92812e-18 (rank : 17)
Query Neighborhood Hits	262	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZL6, Q9HBY3, Q9HBY4, Q9NZL5, Q9UG43, Q9Y2G6	Gene names	RGL1, KIAA0959, RGL
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

RPGF4_HUMAN
NC score	0.708195 (rank : 5)	θ value	5.97985e-28 (rank : 7)
Query Neighborhood Hits	262	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
NC score	0.704876 (rank : 6)	θ value	2.96777e-27 (rank : 8)
Query Neighborhood Hits	262	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RGL1_MOUSE
NC score	0.695315 (rank : 7)	θ value	3.28887e-18 (rank : 18)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q60695	Gene names	Rgl1, Rgl
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

SOS2_HUMAN
NC score	0.694201 (rank : 8)	θ value	2.86786e-30 (rank : 6)
Query Neighborhood Hits	262	Target Neighborhood Hits	193	Shared Neighborhood Hits	30
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

RGL2_HUMAN
NC score	0.685229 (rank : 9)	θ value	4.74913e-17 (rank : 20)
Query Neighborhood Hits	262	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RGL2_MOUSE
NC score	0.682880 (rank : 10)	θ value	1.38178e-16 (rank : 22)
Query Neighborhood Hits	262	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RPGF3_HUMAN
NC score	0.680585 (rank : 11)	θ value	3.39556e-23 (rank : 11)
Query Neighborhood Hits	262	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

GNDS_MOUSE
NC score	0.678404 (rank : 12)	θ value	5.60996e-18 (rank : 19)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

SOS1_MOUSE
NC score	0.669574 (rank : 13)	θ value	1.98606e-31 (rank : 3)
Query Neighborhood Hits	262	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS1_HUMAN
NC score	0.667976 (rank : 14)	θ value	1.6813e-30 (rank : 5)
Query Neighborhood Hits	262	Target Neighborhood Hits	274	Shared Neighborhood Hits	37
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

RPGF2_HUMAN
NC score	0.665492 (rank : 15)	θ value	8.36355e-22 (rank : 13)
Query Neighborhood Hits	262	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

GNDS_HUMAN
NC score	0.665040 (rank : 16)	θ value	1.058e-16 (rank : 21)
Query Neighborhood Hits	262	Target Neighborhood Hits	201	Shared Neighborhood Hits	36
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

RGDSR_HUMAN
NC score	0.657855 (rank : 17)	θ value	1.92812e-18 (rank : 16)
Query Neighborhood Hits	262	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

RPGF3_MOUSE
NC score	0.655439 (rank : 18)	θ value	6.40375e-22 (rank : 12)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

GNRP_HUMAN
NC score	0.653143 (rank : 19)	θ value	1.24399e-33 (rank : 2)
Query Neighborhood Hits	262	Target Neighborhood Hits	239	Shared Neighborhood Hits	24
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
NC score	0.638569 (rank : 20)	θ value	1.28732e-30 (rank : 4)
Query Neighborhood Hits	262	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

RPGF6_HUMAN
NC score	0.638471 (rank : 21)	θ value	1.2077e-20 (rank : 15)
Query Neighborhood Hits	262	Target Neighborhood Hits	266	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

GRP3_HUMAN
NC score	0.598054 (rank : 22)	θ value	1.09232e-21 (rank : 14)
Query Neighborhood Hits	262	Target Neighborhood Hits	131	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

PREX1_HUMAN
NC score	0.132664 (rank : 23)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	262	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

CT152_HUMAN
NC score	0.118030 (rank : 24)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	262	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

FHOD1_HUMAN
NC score	0.099166 (rank : 25)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	262	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CT152_MOUSE
NC score	0.096529 (rank : 26)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	262	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

FMN2_MOUSE
NC score	0.091205 (rank : 27)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	262	Target Neighborhood Hits	349	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMN1B_MOUSE
NC score	0.081872 (rank : 28)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN1A_MOUSE
NC score	0.080382 (rank : 29)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	262	Target Neighborhood Hits	423	Shared Neighborhood Hits	42
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FHOD1_MOUSE
NC score	0.080120 (rank : 30)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	262	Target Neighborhood Hits	217	Shared Neighborhood Hits	37
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

SON_HUMAN
NC score	0.079415 (rank : 31)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	262	Target Neighborhood Hits	1568	Shared Neighborhood Hits	149
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FMN2_HUMAN
NC score	0.078701 (rank : 32)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	262	Target Neighborhood Hits	484	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MUC1_HUMAN
NC score	0.076249 (rank : 33)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	262	Target Neighborhood Hits	975	Shared Neighborhood Hits	128
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SH2D3_HUMAN
NC score	0.075600 (rank : 34)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	262	Target Neighborhood Hits	188	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

RGS3_MOUSE
NC score	0.075511 (rank : 35)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	262	Target Neighborhood Hits	1621	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BCL9_HUMAN
NC score	0.074310 (rank : 36)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	262	Target Neighborhood Hits	1008	Shared Neighborhood Hits	132
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ECT2_HUMAN
NC score	0.072878 (rank : 37)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	262	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

NACAM_MOUSE
NC score	0.072406 (rank : 38)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	262	Target Neighborhood Hits	1866	Shared Neighborhood Hits	153
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DAAM1_HUMAN
NC score	0.072255 (rank : 39)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	262	Target Neighborhood Hits	483	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

PRRT3_HUMAN
NC score	0.070479 (rank : 40)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	262	Target Neighborhood Hits	998	Shared Neighborhood Hits	131
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

DIAP2_HUMAN
NC score	0.069222 (rank : 41)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	262	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

ECT2_MOUSE
NC score	0.069127 (rank : 42)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	262	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

RBM12_MOUSE
NC score	0.068189 (rank : 43)	θ value	0.0113563 (rank : 23)
Query Neighborhood Hits	262	Target Neighborhood Hits	313	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

OGFR_HUMAN
NC score	0.067776 (rank : 44)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	262	Target Neighborhood Hits	1582	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SH2D3_MOUSE
NC score	0.067047 (rank : 45)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	262	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

CO039_MOUSE
NC score	0.066218 (rank : 46)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	262	Target Neighborhood Hits	445	Shared Neighborhood Hits	66
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

FMNL_MOUSE
NC score	0.066050 (rank : 47)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	262	Target Neighborhood Hits	428	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

DIAP2_MOUSE
NC score	0.065482 (rank : 48)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	262	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

KAP1_HUMAN
NC score	0.065358 (rank : 49)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	262	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

NGEF_HUMAN
NC score	0.065073 (rank : 50)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	262	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

FMNL_HUMAN
NC score	0.065013 (rank : 51)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	262	Target Neighborhood Hits	529	Shared Neighborhood Hits	38
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

DAAM2_MOUSE
NC score	0.064646 (rank : 52)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	262	Target Neighborhood Hits	371	Shared Neighborhood Hits	24
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ARHG4_HUMAN
NC score	0.064614 (rank : 53)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	262	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG9_MOUSE
NC score	0.063891 (rank : 54)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	262	Target Neighborhood Hits	234	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

DIAP3_HUMAN
NC score	0.063887 (rank : 55)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	262	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

ARHG9_HUMAN
NC score	0.063527 (rank : 56)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	262	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

KAP1_MOUSE
NC score	0.063361 (rank : 57)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

FGD3_HUMAN
NC score	0.063179 (rank : 58)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	262	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

NCOA6_HUMAN
NC score	0.061835 (rank : 59)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	262	Target Neighborhood Hits	1202	Shared Neighborhood Hits	127
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

DAAM2_HUMAN
NC score	0.061028 (rank : 60)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	262	Target Neighborhood Hits	350	Shared Neighborhood Hits	27
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ARHG7_HUMAN
NC score	0.060851 (rank : 61)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	262	Target Neighborhood Hits	347	Shared Neighborhood Hits	18
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

GP155_HUMAN
NC score	0.060831 (rank : 62)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

FA47B_HUMAN
NC score	0.060542 (rank : 63)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	262	Target Neighborhood Hits	431	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FGD4_HUMAN
NC score	0.060409 (rank : 64)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	262	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

VAV2_MOUSE
NC score	0.059161 (rank : 65)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	262	Target Neighborhood Hits	456	Shared Neighborhood Hits	27
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

DIAP1_HUMAN
NC score	0.059104 (rank : 66)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	262	Target Neighborhood Hits	784	Shared Neighborhood Hits	40
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

FGD4_MOUSE
NC score	0.058643 (rank : 67)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	262	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

DIAP1_MOUSE
NC score	0.058312 (rank : 68)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	262	Target Neighborhood Hits	839	Shared Neighborhood Hits	41
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DAAM1_MOUSE
NC score	0.058082 (rank : 69)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	262	Target Neighborhood Hits	443	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DIAP3_MOUSE
NC score	0.057933 (rank : 70)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	262	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

MDC1_MOUSE
NC score	0.057797 (rank : 71)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	262	Target Neighborhood Hits	998	Shared Neighborhood Hits	100
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RBM12_HUMAN
NC score	0.057772 (rank : 72)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	262	Target Neighborhood Hits	298	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

NGEF_MOUSE
NC score	0.057571 (rank : 73)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	262	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG7_MOUSE
NC score	0.057060 (rank : 74)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	262	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG4_MOUSE
NC score	0.056677 (rank : 75)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	262	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

FGD2_HUMAN
NC score	0.056492 (rank : 76)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	262	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD3_MOUSE
NC score	0.056153 (rank : 77)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	262	Target Neighborhood Hits	257	Shared Neighborhood Hits	13
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

MDC1_HUMAN
NC score	0.056014 (rank : 78)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	262	Target Neighborhood Hits	1446	Shared Neighborhood Hits	103
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SRRM2_MOUSE
NC score	0.056003 (rank : 79)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	262	Target Neighborhood Hits	1470	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

VAV2_HUMAN
NC score	0.055923 (rank : 80)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	262	Target Neighborhood Hits	453	Shared Neighborhood Hits	23
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

RAPH1_HUMAN
NC score	0.055864 (rank : 81)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	262	Target Neighborhood Hits	593	Shared Neighborhood Hits	46
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RGS3_HUMAN
NC score	0.054450 (rank : 82)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	262	Target Neighborhood Hits	1375	Shared Neighborhood Hits	145
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

KAP0_MOUSE
NC score	0.053928 (rank : 83)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP0_HUMAN
NC score	0.053781 (rank : 84)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	262	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

VAV3_MOUSE
NC score	0.053674 (rank : 85)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	262	Target Neighborhood Hits	404	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

BCL9_MOUSE
NC score	0.053341 (rank : 86)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	262	Target Neighborhood Hits	770	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

TARSH_HUMAN
NC score	0.052480 (rank : 87)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	262	Target Neighborhood Hits	768	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

WIRE_MOUSE
NC score	0.052230 (rank : 88)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	262	Target Neighborhood Hits	310	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MLL3_HUMAN
NC score	0.051896 (rank : 89)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	262	Target Neighborhood Hits	1644	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CEL_HUMAN
NC score	0.051745 (rank : 90)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	262	Target Neighborhood Hits	896	Shared Neighborhood Hits	126
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

WHRN_MOUSE
NC score	0.051725 (rank : 91)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	262	Target Neighborhood Hits	412	Shared Neighborhood Hits	46
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

SAPS1_HUMAN
NC score	0.051325 (rank : 92)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	262	Target Neighborhood Hits	704	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

WIRE_HUMAN
NC score	0.051118 (rank : 93)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	262	Target Neighborhood Hits	329	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

KAP2_MOUSE
NC score	0.050942 (rank : 94)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	262	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

SNIP1_HUMAN
NC score	0.050889 (rank : 95)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	262	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

AB1IP_MOUSE
NC score	0.050638 (rank : 96)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	262	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

FA47A_HUMAN
NC score	0.050565 (rank : 97)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	262	Target Neighborhood Hits	451	Shared Neighborhood Hits	75
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FGD1_MOUSE
NC score	0.050481 (rank : 98)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	262	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZIMP7_MOUSE
NC score	0.050237 (rank : 99)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	262	Target Neighborhood Hits	566	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

FGD1_HUMAN
NC score	0.050138 (rank : 100)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	262	Target Neighborhood Hits	367	Shared Neighborhood Hits	27
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

WASIP_MOUSE
NC score	0.049505 (rank : 101)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	262	Target Neighborhood Hits	392	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PCLO_HUMAN
NC score	0.048421 (rank : 102)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	262	Target Neighborhood Hits	2046	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

WASL_MOUSE
NC score	0.047856 (rank : 103)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	262	Target Neighborhood Hits	339	Shared Neighborhood Hits	32
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MTSS1_MOUSE
NC score	0.047580 (rank : 104)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	262	Target Neighborhood Hits	592	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ZIM10_HUMAN
NC score	0.047257 (rank : 105)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	262	Target Neighborhood Hits	577	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CJ078_MOUSE
NC score	0.046090 (rank : 106)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	262	Target Neighborhood Hits	559	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SRRM2_HUMAN
NC score	0.045907 (rank : 107)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	262	Target Neighborhood Hits	1296	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WASIP_HUMAN
NC score	0.045424 (rank : 108)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	262	Target Neighborhood Hits	458	Shared Neighborhood Hits	36
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CC059_HUMAN
NC score	0.044307 (rank : 109)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	262	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYB1, Q86VD8	Gene names	C3orf59
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf59.

PCLO_MOUSE
NC score	0.044058 (rank : 110)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	262	Target Neighborhood Hits	2275	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

VINC_HUMAN
NC score	0.042519 (rank : 111)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	262	Target Neighborhood Hits	145	Shared Neighborhood Hits	10
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

GGN_HUMAN
NC score	0.042157 (rank : 112)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	262	Target Neighborhood Hits	269	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CF015_HUMAN
NC score	0.042000 (rank : 113)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	262	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

PELP1_HUMAN
NC score	0.041470 (rank : 114)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	262	Target Neighborhood Hits	596	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

WASL_HUMAN
NC score	0.040963 (rank : 115)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	262	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PKHA6_MOUSE
NC score	0.040530 (rank : 116)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	262	Target Neighborhood Hits	591	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MILK1_MOUSE
NC score	0.040153 (rank : 117)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	262	Target Neighborhood Hits	788	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRRM1_MOUSE
NC score	0.039704 (rank : 118)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	262	Target Neighborhood Hits	966	Shared Neighborhood Hits	77
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

G3PT_MOUSE
NC score	0.039166 (rank : 119)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	262	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

VINC_MOUSE
NC score	0.039056 (rank : 120)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	262	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

CC059_MOUSE
NC score	0.038905 (rank : 121)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	262	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C525, Q5U4H4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf59 homolog.

SRRM1_HUMAN
NC score	0.038731 (rank : 122)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WASP_MOUSE
NC score	0.038668 (rank : 123)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	262	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

SFRS8_HUMAN
NC score	0.038613 (rank : 124)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	262	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

CT055_MOUSE
NC score	0.038305 (rank : 125)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	262	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

AFAD_HUMAN
NC score	0.037678 (rank : 126)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	262	Target Neighborhood Hits	689	Shared Neighborhood Hits	29
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

S2A4R_HUMAN
NC score	0.037331 (rank : 127)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

ZIM10_MOUSE
NC score	0.037180 (rank : 128)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	262	Target Neighborhood Hits	430	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BRD4_MOUSE
NC score	0.036989 (rank : 129)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	262	Target Neighborhood Hits	845	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

TACC2_MOUSE
NC score	0.036054 (rank : 130)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	262	Target Neighborhood Hits	774	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SYN1_HUMAN
NC score	0.035760 (rank : 131)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	262	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CS016_HUMAN
NC score	0.035232 (rank : 132)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	262	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

PDC6I_HUMAN
NC score	0.035110 (rank : 133)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	262	Target Neighborhood Hits	278	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

HCLS1_HUMAN
NC score	0.035107 (rank : 134)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	262	Target Neighborhood Hits	358	Shared Neighborhood Hits	56
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ICA69_MOUSE
NC score	0.034991 (rank : 135)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	262	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

ABI2_HUMAN
NC score	0.034951 (rank : 136)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	262	Target Neighborhood Hits	350	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

K1849_MOUSE
NC score	0.034866 (rank : 137)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	262	Target Neighborhood Hits	335	Shared Neighborhood Hits	34
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ABI1_HUMAN
NC score	0.034504 (rank : 138)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	262	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

CO5A1_MOUSE
NC score	0.034491 (rank : 139)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	262	Target Neighborhood Hits	419	Shared Neighborhood Hits	35
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

ABI1_MOUSE
NC score	0.034111 (rank : 140)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	262	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_MOUSE
NC score	0.033895 (rank : 141)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	262	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

BRD4_HUMAN
NC score	0.033758 (rank : 142)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	262	Target Neighborhood Hits	851	Shared Neighborhood Hits	46
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

ENL_HUMAN
NC score	0.033754 (rank : 143)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

CO5A1_HUMAN
NC score	0.033554 (rank : 144)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	262	Target Neighborhood Hits	434	Shared Neighborhood Hits	36
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CAP2_MOUSE
NC score	0.033499 (rank : 145)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	262	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYT6, Q80YU7, Q9D6L0	Gene names	Cap2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

YLPM1_MOUSE
NC score	0.033314 (rank : 146)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	262	Target Neighborhood Hits	505	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SYNPO_HUMAN
NC score	0.032710 (rank : 147)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	262	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ABI3_HUMAN
NC score	0.032335 (rank : 148)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	262	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

SNX14_MOUSE
NC score	0.032118 (rank : 149)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

ABI3_MOUSE
NC score	0.032026 (rank : 150)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	262	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

IASPP_MOUSE
NC score	0.031837 (rank : 151)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	262	Target Neighborhood Hits	1024	Shared Neighborhood Hits	94
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

G3PT_HUMAN
NC score	0.031527 (rank : 152)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	262	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

CT055_HUMAN
NC score	0.031480 (rank : 153)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

SNX14_HUMAN
NC score	0.031173 (rank : 154)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	262	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

TACC2_HUMAN
NC score	0.031066 (rank : 155)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	262	Target Neighborhood Hits	856	Shared Neighborhood Hits	49
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

SNP29_MOUSE
NC score	0.029779 (rank : 156)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	262	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERB0, Q3UGN0, Q9DBC5	Gene names	Snap29
Domain Architecture
Description	Synaptosomal-associated protein 29 (SNAP-29) (Vesicle-membrane fusion protein SNAP-29) (Soluble 29 kDa NSF attachment protein) (Golgi SNARE of 32 kDa) (Gs32).

MN1_HUMAN
NC score	0.029729 (rank : 157)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	262	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

PHC2_HUMAN
NC score	0.029397 (rank : 158)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	262	Target Neighborhood Hits	388	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

CAP2_HUMAN
NC score	0.029349 (rank : 159)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	262	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P40123, Q6IAY2	Gene names	CAP2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

CRTC1_HUMAN
NC score	0.029233 (rank : 160)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	262	Target Neighborhood Hits	319	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SYN2_HUMAN
NC score	0.028960 (rank : 161)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	262	Target Neighborhood Hits	213	Shared Neighborhood Hits	18
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYN1_MOUSE
NC score	0.028936 (rank : 162)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	262	Target Neighborhood Hits	363	Shared Neighborhood Hits	30
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

AFF1_MOUSE
NC score	0.028749 (rank : 163)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	262	Target Neighborhood Hits	351	Shared Neighborhood Hits	22
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ZO1_MOUSE
NC score	0.028513 (rank : 164)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	262	Target Neighborhood Hits	453	Shared Neighborhood Hits	25
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

COIA1_MOUSE
NC score	0.028099 (rank : 165)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	262	Target Neighborhood Hits	481	Shared Neighborhood Hits	46
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

ADIPO_MOUSE
NC score	0.027911 (rank : 166)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	262	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

COBA2_HUMAN
NC score	0.027749 (rank : 167)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	262	Target Neighborhood Hits	408	Shared Neighborhood Hits	33
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

NPBL_MOUSE
NC score	0.026918 (rank : 168)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	262	Target Neighborhood Hits	1041	Shared Neighborhood Hits	59
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ABTAP_MOUSE
NC score	0.026856 (rank : 169)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	262	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CS007_MOUSE
NC score	0.026697 (rank : 170)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	262	Target Neighborhood Hits	464	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

COBA1_HUMAN
NC score	0.026444 (rank : 171)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	262	Target Neighborhood Hits	491	Shared Neighborhood Hits	34
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO1A1_MOUSE
NC score	0.026418 (rank : 172)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	262	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CDT1_HUMAN
NC score	0.026331 (rank : 173)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	262	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

COBA1_MOUSE
NC score	0.026274 (rank : 174)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	262	Target Neighborhood Hits	487	Shared Neighborhood Hits	36
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

GSCR1_HUMAN
NC score	0.026265 (rank : 175)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	262	Target Neighborhood Hits	674	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PCQAP_MOUSE
NC score	0.025561 (rank : 176)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	262	Target Neighborhood Hits	506	Shared Neighborhood Hits	22
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

NOLC1_HUMAN
NC score	0.025141 (rank : 177)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	262	Target Neighborhood Hits	452	Shared Neighborhood Hits	20
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

AFF3_HUMAN
NC score	0.024829 (rank : 178)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	262	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

ASPP1_MOUSE
NC score	0.024766 (rank : 179)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	262	Target Neighborhood Hits	1244	Shared Neighborhood Hits	101
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ZN750_HUMAN
NC score	0.024523 (rank : 180)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	262	Target Neighborhood Hits	183	Shared Neighborhood Hits	15
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ICA69_HUMAN
NC score	0.024130 (rank : 181)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	262	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q05084, P78506, Q13824	Gene names	ICA1
Domain Architecture
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

NU214_HUMAN
NC score	0.023738 (rank : 182)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	262	Target Neighborhood Hits	657	Shared Neighborhood Hits	37
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CO4A6_HUMAN
NC score	0.023605 (rank : 183)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	262	Target Neighborhood Hits	318	Shared Neighborhood Hits	26
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

HCLS1_MOUSE
NC score	0.023418 (rank : 184)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	262	Target Neighborhood Hits	329	Shared Neighborhood Hits	45
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PRP2_MOUSE
NC score	0.023190 (rank : 185)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	262	Target Neighborhood Hits	347	Shared Neighborhood Hits	26
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PCGF6_HUMAN
NC score	0.023174 (rank : 186)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	262	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

CS007_HUMAN
NC score	0.023163 (rank : 187)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	262	Target Neighborhood Hits	401	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PHLB1_MOUSE
NC score	0.022806 (rank : 188)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	262	Target Neighborhood Hits	678	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ZN598_MOUSE
NC score	0.022790 (rank : 189)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	262	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

TRI66_HUMAN
NC score	0.022667 (rank : 190)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	262	Target Neighborhood Hits	479	Shared Neighborhood Hits	32
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UBE4B_HUMAN
NC score	0.022522 (rank : 191)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	262	Target Neighborhood Hits	158	Shared Neighborhood Hits	14
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

C1QT5_MOUSE
NC score	0.022369 (rank : 192)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	262	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

ABTAP_HUMAN
NC score	0.022352 (rank : 193)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	262	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

HDAC6_MOUSE
NC score	0.022312 (rank : 194)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	262	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

CO4A2_HUMAN
NC score	0.022268 (rank : 195)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	262	Target Neighborhood Hits	454	Shared Neighborhood Hits	43
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

C1QT5_HUMAN
NC score	0.022133 (rank : 196)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

MBD6_HUMAN
NC score	0.021510 (rank : 197)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	262	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

WASF3_HUMAN
NC score	0.021227 (rank : 198)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	262	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

ENAH_MOUSE
NC score	0.020975 (rank : 199)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	262	Target Neighborhood Hits	919	Shared Neighborhood Hits	47
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CO9A1_HUMAN
NC score	0.020651 (rank : 200)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	262	Target Neighborhood Hits	420	Shared Neighborhood Hits	33
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

MLL4_HUMAN
NC score	0.020541 (rank : 201)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	262	Target Neighborhood Hits	722	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

BRD3_HUMAN
NC score	0.020362 (rank : 202)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	262	Target Neighborhood Hits	369	Shared Neighborhood Hits	17
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

EMIL2_MOUSE
NC score	0.020333 (rank : 203)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	262	Target Neighborhood Hits	485	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

PDCD7_MOUSE
NC score	0.020197 (rank : 204)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	262	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

TMM24_MOUSE
NC score	0.020144 (rank : 205)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	262	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

SF01_MOUSE
NC score	0.020128 (rank : 206)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	262	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ABRA_HUMAN
NC score	0.019893 (rank : 207)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	262	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

SF01_HUMAN
NC score	0.019760 (rank : 208)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	262	Target Neighborhood Hits	287	Shared Neighborhood Hits	20
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

RERE_MOUSE
NC score	0.019643 (rank : 209)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	262	Target Neighborhood Hits	785	Shared Neighborhood Hits	49
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SET1A_HUMAN
NC score	0.019596 (rank : 210)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	37
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SGIP1_MOUSE
NC score	0.019596 (rank : 211)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	262	Target Neighborhood Hits	180	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CREB5_HUMAN
NC score	0.019033 (rank : 212)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	262	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

PTN22_MOUSE
NC score	0.018944 (rank : 213)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	262	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

SQSTM_MOUSE
NC score	0.018855 (rank : 214)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	262	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

ADDA_MOUSE
NC score	0.018458 (rank : 215)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	262	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

BACH1_HUMAN
NC score	0.018224 (rank : 216)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	262	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

KCNN1_HUMAN
NC score	0.017672 (rank : 217)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	262	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

SHAN1_HUMAN
NC score	0.017585 (rank : 218)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	262	Target Neighborhood Hits	1041	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ARHG1_MOUSE
NC score	0.017435 (rank : 219)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	262	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

RFIP1_MOUSE
NC score	0.017100 (rank : 220)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	262	Target Neighborhood Hits	152	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

MAGC2_HUMAN
NC score	0.016965 (rank : 221)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	262	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBF1, Q5JZ00, Q96D45, Q9P1M6, Q9P1M7	Gene names	MAGEC2, HCA587, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen C2 (MAGE-C2 antigen) (MAGE-E1 antigen) (Hepatocellular carcinoma-associated antigen 587) (Cancer-testis antigen 10) (CT10).

PK1L1_HUMAN
NC score	0.016831 (rank : 222)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

UBE4B_MOUSE
NC score	0.016821 (rank : 223)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES00, Q9EQE0	Gene names	Ube4b, Ufd2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Ufd2a).

SATB1_MOUSE
NC score	0.016805 (rank : 224)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	262	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

TEX2_MOUSE
NC score	0.016667 (rank : 225)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	262	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

STAG3_HUMAN
NC score	0.016334 (rank : 226)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	262	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

NFAC4_HUMAN
NC score	0.016333 (rank : 227)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	262	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

K0460_MOUSE
NC score	0.016203 (rank : 228)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	262	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MORC2_HUMAN
NC score	0.016140 (rank : 229)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	262	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

CLCN1_MOUSE
NC score	0.015806 (rank : 230)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	262	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

DLGP4_HUMAN
NC score	0.015710 (rank : 231)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	262	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

CCNK_MOUSE
NC score	0.015696 (rank : 232)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	262	Target Neighborhood Hits	350	Shared Neighborhood Hits	26
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CCDC6_HUMAN
NC score	0.015657 (rank : 233)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	262	Target Neighborhood Hits	723	Shared Neighborhood Hits	15
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

HCN4_MOUSE
NC score	0.015561 (rank : 234)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	262	Target Neighborhood Hits	284	Shared Neighborhood Hits	14
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

FIP1_MOUSE
NC score	0.015246 (rank : 235)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	262	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

AIRE_HUMAN
NC score	0.014947 (rank : 236)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	262	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

KCNQ4_HUMAN
NC score	0.014920 (rank : 237)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	262	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

DYN2_HUMAN
NC score	0.014918 (rank : 238)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	262	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

OST4_HUMAN
NC score	0.014830 (rank : 239)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	262	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

CNOT3_HUMAN
NC score	0.014737 (rank : 240)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	262	Target Neighborhood Hits	425	Shared Neighborhood Hits	21
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SMCA4_HUMAN
NC score	0.014532 (rank : 241)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	262	Target Neighborhood Hits	597	Shared Neighborhood Hits	35
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

FA54A_MOUSE
NC score	0.013840 (rank : 242)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	262	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VED8	Gene names	Fam54a, Dufd1
Domain Architecture	No domain graphic available
Description	Protein FAM54A (DUF729 domain-containing protein 1).

UBP53_MOUSE
NC score	0.013751 (rank : 243)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	262	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

SFR17_HUMAN
NC score	0.012761 (rank : 244)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	262	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

CSKI1_HUMAN
NC score	0.012705 (rank : 245)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	262	Target Neighborhood Hits	997	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RUSC1_HUMAN
NC score	0.011808 (rank : 246)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	262	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

ST5_MOUSE
NC score	0.011370 (rank : 247)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	262	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

KCNQ2_HUMAN
NC score	0.011173 (rank : 248)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	262	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

TTC12_HUMAN
NC score	0.011131 (rank : 249)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	262	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

KCNC3_HUMAN
NC score	0.011032 (rank : 250)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	262	Target Neighborhood Hits	256	Shared Neighborhood Hits	23
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

SMCA2_HUMAN
NC score	0.010937 (rank : 251)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	262	Target Neighborhood Hits	503	Shared Neighborhood Hits	26
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

APBA1_HUMAN
NC score	0.010865 (rank : 252)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	262	Target Neighborhood Hits	325	Shared Neighborhood Hits	23
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CABC1_MOUSE
NC score	0.009994 (rank : 253)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	262	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q60936, Q8K0M1	Gene names	Cabc1
Domain Architecture
Description	Chaperone-activity of bc1 complex-like, mitochondrial precursor (Chaperone-ABC1-like).

TREF1_HUMAN
NC score	0.009970 (rank : 254)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	262	Target Neighborhood Hits	651	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

GP1BA_HUMAN
NC score	0.009933 (rank : 255)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	262	Target Neighborhood Hits	407	Shared Neighborhood Hits	16
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

TM16H_HUMAN
NC score	0.009925 (rank : 256)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	262	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

PTN12_MOUSE
NC score	0.009752 (rank : 257)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	262	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

TREF1_MOUSE
NC score	0.009747 (rank : 258)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	262	Target Neighborhood Hits	682	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

E2F2_HUMAN
NC score	0.009602 (rank : 259)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	262	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

ATRIP_HUMAN
NC score	0.009513 (rank : 260)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	262	Target Neighborhood Hits	249	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

HXA3_MOUSE
NC score	0.009231 (rank : 261)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	262	Target Neighborhood Hits	558	Shared Neighborhood Hits	26
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

DOC2B_MOUSE
NC score	0.009110 (rank : 262)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	262	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

CBX6_HUMAN
NC score	0.009010 (rank : 263)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	262	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

EMBP_MOUSE
NC score	0.008720 (rank : 264)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	262	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

CCD93_MOUSE
NC score	0.008223 (rank : 265)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	262	Target Neighborhood Hits	362	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

HXA3_HUMAN
NC score	0.008153 (rank : 266)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	262	Target Neighborhood Hits	535	Shared Neighborhood Hits	30
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

BAI1_HUMAN
NC score	0.007983 (rank : 267)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	262	Target Neighborhood Hits	375	Shared Neighborhood Hits	19
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

FNDC3_HUMAN
NC score	0.007862 (rank : 268)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	262	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ARX_HUMAN
NC score	0.007740 (rank : 269)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	262	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

DAB2P_HUMAN
NC score	0.007707 (rank : 270)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	262	Target Neighborhood Hits	303	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

PRDM2_HUMAN
NC score	0.007437 (rank : 271)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	262	Target Neighborhood Hits	1135	Shared Neighborhood Hits	40
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

COA1_HUMAN
NC score	0.007183 (rank : 272)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

HXD3_MOUSE
NC score	0.006937 (rank : 273)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	262	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

IGHE_MOUSE
NC score	0.006825 (rank : 274)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	262	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	P06336, P01856	Gene names
Domain Architecture
Description	Ig epsilon chain C region.

SPEG_HUMAN
NC score	0.006706 (rank : 275)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	262	Target Neighborhood Hits	1762	Shared Neighborhood Hits	73
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

NKX24_HUMAN
NC score	0.006566 (rank : 276)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	262	Target Neighborhood Hits	366	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

CD2L7_HUMAN
NC score	0.006340 (rank : 277)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	262	Target Neighborhood Hits	1275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

ARX_MOUSE
NC score	0.006065 (rank : 278)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	262	Target Neighborhood Hits	398	Shared Neighborhood Hits	15
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

JHD3B_MOUSE
NC score	0.005981 (rank : 279)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	262	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

NKX24_MOUSE
NC score	0.005837 (rank : 280)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	262	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQM3, Q9EQM4	Gene names	Nkx2-4, Nkx2d
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

GLI2_HUMAN
NC score	0.005417 (rank : 281)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	262	Target Neighborhood Hits	971	Shared Neighborhood Hits	42
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NFH_HUMAN
NC score	0.005372 (rank : 282)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	262	Target Neighborhood Hits	1242	Shared Neighborhood Hits	40
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

P85B_MOUSE
NC score	0.005170 (rank : 283)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	262	Target Neighborhood Hits	519	Shared Neighborhood Hits	12
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

FZD8_MOUSE
NC score	0.005142 (rank : 284)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	262	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FBLI1_MOUSE
NC score	0.004503 (rank : 285)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	262	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

NFKB1_MOUSE
NC score	0.004213 (rank : 286)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	262	Target Neighborhood Hits	300	Shared Neighborhood Hits	8
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

RORG_HUMAN
NC score	0.004167 (rank : 287)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	262	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

NFKB1_HUMAN
NC score	0.003972 (rank : 288)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	262	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

SYNE2_HUMAN
NC score	0.003953 (rank : 289)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	262	Target Neighborhood Hits	1323	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TITIN_HUMAN
NC score	0.003688 (rank : 290)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	262	Target Neighborhood Hits	2923	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ACRO_HUMAN
NC score	0.003438 (rank : 291)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	262	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

FOXGB_MOUSE
NC score	0.003079 (rank : 292)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	262	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

FOXL2_HUMAN
NC score	0.002856 (rank : 293)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

RBCC1_MOUSE
NC score	0.002830 (rank : 294)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	262	Target Neighborhood Hits	1048	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

AGRIN_HUMAN
NC score	0.002539 (rank : 295)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	262	Target Neighborhood Hits	582	Shared Neighborhood Hits	13
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

MEGF8_HUMAN
NC score	0.002008 (rank : 296)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	262	Target Neighborhood Hits	528	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ZN219_HUMAN
NC score	0.001538 (rank : 297)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	262	Target Neighborhood Hits	876	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

CD2L6_MOUSE
NC score	0.000704 (rank : 298)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	262	Target Neighborhood Hits	851	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

SP5_HUMAN
NC score	0.000655 (rank : 299)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	262	Target Neighborhood Hits	832	Shared Neighborhood Hits	33
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

ZN580_MOUSE
NC score	0.000331 (rank : 300)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	262	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

INSM1_HUMAN
NC score	0.000275 (rank : 301)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	262	Target Neighborhood Hits	683	Shared Neighborhood Hits	11
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

SN1L2_HUMAN
NC score	-0.000192 (rank : 302)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	262	Target Neighborhood Hits	964	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

ABL2_HUMAN
NC score	-0.000703 (rank : 303)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	262	Target Neighborhood Hits	1045	Shared Neighborhood Hits	20
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

LATS1_MOUSE
NC score	-0.001065 (rank : 304)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	262	Target Neighborhood Hits	1027	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MTF1_MOUSE
NC score	-0.001129 (rank : 305)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	262	Target Neighborhood Hits	785	Shared Neighborhood Hits	17
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

M4K1_MOUSE
NC score	-0.001195 (rank : 306)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	262	Target Neighborhood Hits	858	Shared Neighborhood Hits	11
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

CTCF_MOUSE
NC score	-0.002898 (rank : 307)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	262	Target Neighborhood Hits	796	Shared Neighborhood Hits	16
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

LRRK2_HUMAN
NC score	-0.003081 (rank : 308)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	262	Target Neighborhood Hits	1382	Shared Neighborhood Hits	10
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

ZN619_HUMAN
NC score	-0.003921 (rank : 309)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	262	Target Neighborhood Hits	749	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2I2	Gene names	ZNF619
Domain Architecture	No domain graphic available
Description	Zinc finger protein 619.

ADA1B_MOUSE
NC score	-0.004022 (rank : 310)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	262	Target Neighborhood Hits	966	Shared Neighborhood Hits	6
SwissProt Accessions	P97717	Gene names	Adra1b
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).