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Network neighborhood for query Sequence : CT152_HUMAN

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CT152_HUMAN
 
SwissProt Accessions Q96M20, Q5T3S1, Q9BR36, Q9BWY5 Gene names C20orf152
Domain
Architecture
Description Uncharacterized protein C20orf152.
Rank Plots


Hits sorted by θ


CT152_HUMAN
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 30 Target Neighborhood Hits 30 Shared Neighborhood Hits 30
SwissProt Accessions Q96M20, Q5T3S1, Q9BR36, Q9BWY5 Gene names C20orf152
Domain
Architecture
Description Uncharacterized protein C20orf152.
CT152_MOUSE
 
θ value 0 (rank : 2) NC score 0.980696 (rank : 2)
Query Neighborhood Hits 30 Target Neighborhood Hits 38 Shared Neighborhood Hits 29
SwissProt Accessions Q9D5U8, Q8R083 Gene names
Domain
Architecture
Description Uncharacterized protein C20orf152 homolog.
RPGF4_HUMAN
 
θ value 1.06045e-08 (rank : 3) NC score 0.367894 (rank : 5)
Query Neighborhood Hits 30 Target Neighborhood Hits 88 Shared Neighborhood Hits 23
SwissProt Accessions Q8WZA2, O95636, Q8IXK6, Q8TAA4 Gene names RAPGEF4, CGEF2, EPAC2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).
KGP1A_HUMAN
 
θ value 1.80886e-08 (rank : 4) NC score 0.115544 (rank : 28)
Query Neighborhood Hits 30 Target Neighborhood Hits 901 Shared Neighborhood Hits 27
SwissProt Accessions Q13976 Gene names PRKG1, PRKGR1A
Domain
Architecture
Description cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).
KGP1B_HUMAN
 
θ value 1.80886e-08 (rank : 5) NC score 0.115975 (rank : 26)
Query Neighborhood Hits 30 Target Neighborhood Hits 921 Shared Neighborhood Hits 27
SwissProt Accessions P14619 Gene names PRKG1, PRKG1B, PRKGR1B
Domain
Architecture
Description cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).
RPGF3_HUMAN
 
θ value 2.36244e-08 (rank : 6) NC score 0.393680 (rank : 4)
Query Neighborhood Hits 30 Target Neighborhood Hits 56 Shared Neighborhood Hits 24
SwissProt Accessions O95398, O95634, Q8WVN0 Gene names RAPGEF3, CGEF1, EPAC, EPAC1
Domain
Architecture
Description Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).
RPGF3_MOUSE
 
θ value 4.0297e-08 (rank : 7) NC score 0.395105 (rank : 3)
Query Neighborhood Hits 30 Target Neighborhood Hits 54 Shared Neighborhood Hits 25
SwissProt Accessions Q8VCC8, Q8BZK9, Q8R1R1 Gene names Rapgef3, Epac, Epac1
Domain
Architecture
Description Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).
RPGF4_MOUSE
 
θ value 6.87365e-08 (rank : 8) NC score 0.365849 (rank : 6)
Query Neighborhood Hits 30 Target Neighborhood Hits 80 Shared Neighborhood Hits 23
SwissProt Accessions Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0 Gene names Rapgef4, Cgef2, Epac2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).
KGP1B_MOUSE
 
θ value 1.17247e-07 (rank : 9) NC score 0.114055 (rank : 30)
Query Neighborhood Hits 30 Target Neighborhood Hits 922 Shared Neighborhood Hits 27
SwissProt Accessions Q9Z0Z0 Gene names Prkg1, Prkg1b, Prkgr1b
Domain
Architecture
Description cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).
KGP2_HUMAN
 
θ value 2.21117e-06 (rank : 10) NC score 0.113533 (rank : 32)
Query Neighborhood Hits 30 Target Neighborhood Hits 1023 Shared Neighborhood Hits 27
SwissProt Accessions Q13237, O00125, O60916 Gene names PRKG2, PRKGR2
Domain
Architecture
Description cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).
KGP2_MOUSE
 
θ value 2.21117e-06 (rank : 11) NC score 0.113675 (rank : 31)
Query Neighborhood Hits 30 Target Neighborhood Hits 1029 Shared Neighborhood Hits 27
SwissProt Accessions Q61410 Gene names Prkg2, Prkgr2
Domain
Architecture
Description cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).
RPGF6_HUMAN
 
θ value 0.000602161 (rank : 12) NC score 0.214281 (rank : 15)
Query Neighborhood Hits 30 Target Neighborhood Hits 266 Shared Neighborhood Hits 15
SwissProt Accessions Q8TEU7, Q8NI21, Q8TEU6, Q96PC1 Gene names RAPGEF6, PDZGEF2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).
RPGF2_HUMAN
 
θ value 0.00665767 (rank : 13) NC score 0.189305 (rank : 18)
Query Neighborhood Hits 30 Target Neighborhood Hits 242 Shared Neighborhood Hits 8
SwissProt Accessions Q9Y4G8 Gene names RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain
Architecture

No domain graphic available

Description Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).
KAP0_HUMAN
 
θ value 0.00869519 (rank : 14) NC score 0.340867 (rank : 10)
Query Neighborhood Hits 30 Target Neighborhood Hits 52 Shared Neighborhood Hits 28
SwissProt Accessions P10644, Q567S7 Gene names PRKAR1A, PKR1, PRKAR1
Domain
Architecture
Description cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).
KAP1_HUMAN
 
θ value 0.0113563 (rank : 15) NC score 0.349502 (rank : 7)
Query Neighborhood Hits 30 Target Neighborhood Hits 58 Shared Neighborhood Hits 28
SwissProt Accessions P31321 Gene names PRKAR1B
Domain
Architecture
Description cAMP-dependent protein kinase type I-beta regulatory subunit.
KAP2_MOUSE
 
θ value 0.0113563 (rank : 16) NC score 0.324396 (rank : 11)
Query Neighborhood Hits 30 Target Neighborhood Hits 44 Shared Neighborhood Hits 26
SwissProt Accessions P12367 Gene names Prkar2a
Domain
Architecture
Description cAMP-dependent protein kinase type II-alpha regulatory subunit.
KAP0_MOUSE
 
θ value 0.0148317 (rank : 17) NC score 0.341374 (rank : 9)
Query Neighborhood Hits 30 Target Neighborhood Hits 48 Shared Neighborhood Hits 28
SwissProt Accessions Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6 Gene names Prkar1a
Domain
Architecture

No domain graphic available

Description cAMP-dependent protein kinase type I-alpha regulatory subunit.
KAP1_MOUSE
 
θ value 0.0193708 (rank : 18) NC score 0.344560 (rank : 8)
Query Neighborhood Hits 30 Target Neighborhood Hits 49 Shared Neighborhood Hits 28
SwissProt Accessions P12849 Gene names Prkar1b
Domain
Architecture
Description cAMP-dependent protein kinase type I-beta regulatory subunit.
CNGA2_MOUSE
 
θ value 0.0330416 (rank : 19) NC score 0.122488 (rank : 22)
Query Neighborhood Hits 30 Target Neighborhood Hits 86 Shared Neighborhood Hits 23
SwissProt Accessions Q62398 Gene names Cnga2, Cncg2, Cncg4
Domain
Architecture
Description Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).
KAP2_HUMAN
 
θ value 0.0431538 (rank : 20) NC score 0.313551 (rank : 12)
Query Neighborhood Hits 30 Target Neighborhood Hits 48 Shared Neighborhood Hits 25
SwissProt Accessions P13861, Q16823 Gene names PRKAR2A, PKR2, PRKAR2
Domain
Architecture
Description cAMP-dependent protein kinase type II-alpha regulatory subunit.
CNGB1_HUMAN
 
θ value 0.0736092 (rank : 21) NC score 0.163867 (rank : 19)
Query Neighborhood Hits 30 Target Neighborhood Hits 222 Shared Neighborhood Hits 27
SwissProt Accessions Q14028, Q14029 Gene names CNGB1, CNCG4
Domain
Architecture
Description Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).
CNGA3_HUMAN
 
θ value 1.06291 (rank : 22) NC score 0.119001 (rank : 23)
Query Neighborhood Hits 30 Target Neighborhood Hits 125 Shared Neighborhood Hits 23
SwissProt Accessions Q16281, Q9UP64 Gene names CNGA3, CNCG3
Domain
Architecture
Description Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).
CNGA3_MOUSE
 
θ value 1.06291 (rank : 23) NC score 0.118003 (rank : 25)
Query Neighborhood Hits 30 Target Neighborhood Hits 84 Shared Neighborhood Hits 23
SwissProt Accessions Q9JJZ8, Q9WV01 Gene names Cnga3, Cng3
Domain
Architecture
Description Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).
CNGA1_HUMAN
 
θ value 1.38821 (rank : 24) NC score 0.115950 (rank : 27)
Query Neighborhood Hits 30 Target Neighborhood Hits 149 Shared Neighborhood Hits 25
SwissProt Accessions P29973, Q16279, Q16485 Gene names CNGA1, CNCG, CNCG1
Domain
Architecture
Description cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).
CNGA1_MOUSE
 
θ value 1.38821 (rank : 25) NC score 0.114275 (rank : 29)
Query Neighborhood Hits 30 Target Neighborhood Hits 198 Shared Neighborhood Hits 25
SwissProt Accessions P29974, Q60776 Gene names Cnga1, Cncg, Cncg1
Domain
Architecture
Description cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).
CNGB3_HUMAN
 
θ value 1.81305 (rank : 26) NC score 0.136701 (rank : 20)
Query Neighborhood Hits 30 Target Neighborhood Hits 206 Shared Neighborhood Hits 25
SwissProt Accessions Q9NQW8, Q9NRE9 Gene names CNGB3
Domain
Architecture
Description Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).
HCN4_HUMAN
 
θ value 3.0926 (rank : 27) NC score 0.095929 (rank : 34)
Query Neighborhood Hits 30 Target Neighborhood Hits 303 Shared Neighborhood Hits 23
SwissProt Accessions Q9Y3Q4, Q9UMQ7 Gene names HCN4
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.
HCN4_MOUSE
 
θ value 3.0926 (rank : 28) NC score 0.097353 (rank : 33)
Query Neighborhood Hits 30 Target Neighborhood Hits 284 Shared Neighborhood Hits 23
SwissProt Accessions O70507 Gene names Hcn4, Bcng3
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).
SI1L2_HUMAN
 
θ value 5.27518 (rank : 29) NC score 0.019960 (rank : 49)
Query Neighborhood Hits 30 Target Neighborhood Hits 131 Shared Neighborhood Hits 4
SwissProt Accessions Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6 Gene names SIPA1L2, KIAA1389
Domain
Architecture

No domain graphic available

Description Signal-induced proliferation-associated 1-like protein 2.
CNGB3_MOUSE
 
θ value 6.88961 (rank : 30) NC score 0.132862 (rank : 21)
Query Neighborhood Hits 30 Target Neighborhood Hits 74 Shared Neighborhood Hits 26
SwissProt Accessions Q9JJZ9 Gene names Cngb3, Cng6
Domain
Architecture
Description Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).
GNDS_MOUSE
 
θ value θ > 10 (rank : 31) NC score 0.051841 (rank : 48)
Query Neighborhood Hits 30 Target Neighborhood Hits 115 Shared Neighborhood Hits 6
SwissProt Accessions Q03385 Gene names Ralgds, Rgds
Domain
Architecture
Description Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).
GNRP_HUMAN
 
θ value θ > 10 (rank : 32) NC score 0.070828 (rank : 42)
Query Neighborhood Hits 30 Target Neighborhood Hits 239 Shared Neighborhood Hits 6
SwissProt Accessions Q13972, Q16027 Gene names RASGRF1, CDC25
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).
GNRP_MOUSE
 
θ value θ > 10 (rank : 33) NC score 0.069171 (rank : 43)
Query Neighborhood Hits 30 Target Neighborhood Hits 191 Shared Neighborhood Hits 6
SwissProt Accessions P27671 Gene names Rasgrf1, Cdc25, Grf1
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).
GRP3_HUMAN
 
θ value θ > 10 (rank : 34) NC score 0.079720 (rank : 41)
Query Neighborhood Hits 30 Target Neighborhood Hits 131 Shared Neighborhood Hits 6
SwissProt Accessions Q8IV61, O94931 Gene names RASGRP3, GRP3, KIAA0846
Domain
Architecture
Description RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).
HCN1_HUMAN
 
θ value θ > 10 (rank : 35) NC score 0.081805 (rank : 39)
Query Neighborhood Hits 30 Target Neighborhood Hits 120 Shared Neighborhood Hits 22
SwissProt Accessions O60741 Gene names HCN1, BCNG1
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).
HCN1_MOUSE
 
θ value θ > 10 (rank : 36) NC score 0.081147 (rank : 40)
Query Neighborhood Hits 30 Target Neighborhood Hits 172 Shared Neighborhood Hits 22
SwissProt Accessions O88704, O54899, Q9D613 Gene names Hcn1, Bcng1, Hac2
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).
HCN2_HUMAN
 
θ value θ > 10 (rank : 37) NC score 0.090954 (rank : 36)
Query Neighborhood Hits 30 Target Neighborhood Hits 369 Shared Neighborhood Hits 24
SwissProt Accessions Q9UL51, O60742, O60743, O75267, Q9UBS2 Gene names HCN2, BCNG2
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).
HCN2_MOUSE
 
θ value θ > 10 (rank : 38) NC score 0.092206 (rank : 35)
Query Neighborhood Hits 30 Target Neighborhood Hits 278 Shared Neighborhood Hits 24
SwissProt Accessions O88703, O70506 Gene names Hcn2, Bcng2, Hac1
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).
HCN3_HUMAN
 
θ value θ > 10 (rank : 39) NC score 0.082055 (rank : 38)
Query Neighborhood Hits 30 Target Neighborhood Hits 99 Shared Neighborhood Hits 22
SwissProt Accessions Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2 Gene names HCN3, KIAA1535
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
HCN3_MOUSE
 
θ value θ > 10 (rank : 40) NC score 0.082235 (rank : 37)
Query Neighborhood Hits 30 Target Neighborhood Hits 112 Shared Neighborhood Hits 22
SwissProt Accessions O88705 Gene names Hcn3, Hac3
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).
KAP3_HUMAN
 
θ value θ > 10 (rank : 41) NC score 0.276875 (rank : 14)
Query Neighborhood Hits 30 Target Neighborhood Hits 40 Shared Neighborhood Hits 28
SwissProt Accessions P31323 Gene names PRKAR2B
Domain
Architecture
Description cAMP-dependent protein kinase type II-beta regulatory subunit.
KAP3_MOUSE
 
θ value θ > 10 (rank : 42) NC score 0.280371 (rank : 13)
Query Neighborhood Hits 30 Target Neighborhood Hits 43 Shared Neighborhood Hits 28
SwissProt Accessions P31324, Q3UTZ1, Q80ZM4, Q8BRZ7 Gene names Prkar2b
Domain
Architecture

No domain graphic available

Description cAMP-dependent protein kinase type II-beta regulatory subunit.
RGL1_HUMAN
 
θ value θ > 10 (rank : 43) NC score 0.052009 (rank : 47)
Query Neighborhood Hits 30 Target Neighborhood Hits 43 Shared Neighborhood Hits 6
SwissProt Accessions Q9NZL6, Q9HBY3, Q9HBY4, Q9NZL5, Q9UG43, Q9Y2G6 Gene names RGL1, KIAA0959, RGL
Domain
Architecture
Description Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).
RPGF1_HUMAN
 
θ value θ > 10 (rank : 44) NC score 0.118030 (rank : 24)
Query Neighborhood Hits 30 Target Neighborhood Hits 262 Shared Neighborhood Hits 7
SwissProt Accessions Q13905 Gene names RAPGEF1, GRF2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).
RPGF5_HUMAN
 
θ value θ > 10 (rank : 45) NC score 0.192195 (rank : 17)
Query Neighborhood Hits 30 Target Neighborhood Hits 42 Shared Neighborhood Hits 6
SwissProt Accessions Q92565, Q8IXU5 Gene names RAPGEF5, GFR, KIAA0277, MRGEF
Domain
Architecture
Description Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).
RPGF5_MOUSE
 
θ value θ > 10 (rank : 46) NC score 0.193876 (rank : 16)
Query Neighborhood Hits 30 Target Neighborhood Hits 85 Shared Neighborhood Hits 6
SwissProt Accessions Q8C0Q9, Q8BJJ9, Q8C0R5 Gene names Rapgef5, Gfr, Kiaa0277, Mrgef
Domain
Architecture
Description Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).
SOS1_HUMAN
 
θ value θ > 10 (rank : 47) NC score 0.068097 (rank : 45)
Query Neighborhood Hits 30 Target Neighborhood Hits 274 Shared Neighborhood Hits 6
SwissProt Accessions Q07889 Gene names SOS1
Domain
Architecture
Description Son of sevenless homolog 1 (SOS-1).
SOS1_MOUSE
 
θ value θ > 10 (rank : 48) NC score 0.067736 (rank : 46)
Query Neighborhood Hits 30 Target Neighborhood Hits 281 Shared Neighborhood Hits 6
SwissProt Accessions Q62245, Q62244 Gene names Sos1
Domain
Architecture
Description Son of sevenless homolog 1 (SOS-1) (mSOS-1).
SOS2_HUMAN
 
θ value θ > 10 (rank : 49) NC score 0.068958 (rank : 44)
Query Neighborhood Hits 30 Target Neighborhood Hits 193 Shared Neighborhood Hits 6
SwissProt Accessions Q07890, Q15503 Gene names SOS2
Domain
Architecture
Description Son of sevenless homolog 2 (SOS-2).

Hits sorted by NC score


CT152_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 30 Target Neighborhood Hits 30 Shared Neighborhood Hits 30
SwissProt Accessions Q96M20, Q5T3S1, Q9BR36, Q9BWY5 Gene names C20orf152
Domain
Architecture
Description Uncharacterized protein C20orf152.
CT152_MOUSE
 
NC score 0.980696 (rank : 2) θ value 0 (rank : 2)
Query Neighborhood Hits 30 Target Neighborhood Hits 38 Shared Neighborhood Hits 29
SwissProt Accessions Q9D5U8, Q8R083 Gene names
Domain
Architecture
Description Uncharacterized protein C20orf152 homolog.
RPGF3_MOUSE
 
NC score 0.395105 (rank : 3) θ value 4.0297e-08 (rank : 7)
Query Neighborhood Hits 30 Target Neighborhood Hits 54 Shared Neighborhood Hits 25
SwissProt Accessions Q8VCC8, Q8BZK9, Q8R1R1 Gene names Rapgef3, Epac, Epac1
Domain
Architecture
Description Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).
RPGF3_HUMAN
 
NC score 0.393680 (rank : 4) θ value 2.36244e-08 (rank : 6)
Query Neighborhood Hits 30 Target Neighborhood Hits 56 Shared Neighborhood Hits 24
SwissProt Accessions O95398, O95634, Q8WVN0 Gene names RAPGEF3, CGEF1, EPAC, EPAC1
Domain
Architecture
Description Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).
RPGF4_HUMAN
 
NC score 0.367894 (rank : 5) θ value 1.06045e-08 (rank : 3)
Query Neighborhood Hits 30 Target Neighborhood Hits 88 Shared Neighborhood Hits 23
SwissProt Accessions Q8WZA2, O95636, Q8IXK6, Q8TAA4 Gene names RAPGEF4, CGEF2, EPAC2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).
RPGF4_MOUSE
 
NC score 0.365849 (rank : 6) θ value 6.87365e-08 (rank : 8)
Query Neighborhood Hits 30 Target Neighborhood Hits 80 Shared Neighborhood Hits 23
SwissProt Accessions Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0 Gene names Rapgef4, Cgef2, Epac2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).
KAP1_HUMAN
 
NC score 0.349502 (rank : 7) θ value 0.0113563 (rank : 15)
Query Neighborhood Hits 30 Target Neighborhood Hits 58 Shared Neighborhood Hits 28
SwissProt Accessions P31321 Gene names PRKAR1B
Domain
Architecture
Description cAMP-dependent protein kinase type I-beta regulatory subunit.
KAP1_MOUSE
 
NC score 0.344560 (rank : 8) θ value 0.0193708 (rank : 18)
Query Neighborhood Hits 30 Target Neighborhood Hits 49 Shared Neighborhood Hits 28
SwissProt Accessions P12849 Gene names Prkar1b
Domain
Architecture
Description cAMP-dependent protein kinase type I-beta regulatory subunit.
KAP0_MOUSE
 
NC score 0.341374 (rank : 9) θ value 0.0148317 (rank : 17)
Query Neighborhood Hits 30 Target Neighborhood Hits 48 Shared Neighborhood Hits 28
SwissProt Accessions Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6 Gene names Prkar1a
Domain
Architecture

No domain graphic available

Description cAMP-dependent protein kinase type I-alpha regulatory subunit.
KAP0_HUMAN
 
NC score 0.340867 (rank : 10) θ value 0.00869519 (rank : 14)
Query Neighborhood Hits 30 Target Neighborhood Hits 52 Shared Neighborhood Hits 28
SwissProt Accessions P10644, Q567S7 Gene names PRKAR1A, PKR1, PRKAR1
Domain
Architecture
Description cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).
KAP2_MOUSE
 
NC score 0.324396 (rank : 11) θ value 0.0113563 (rank : 16)
Query Neighborhood Hits 30 Target Neighborhood Hits 44 Shared Neighborhood Hits 26
SwissProt Accessions P12367 Gene names Prkar2a
Domain
Architecture
Description cAMP-dependent protein kinase type II-alpha regulatory subunit.
KAP2_HUMAN
 
NC score 0.313551 (rank : 12) θ value 0.0431538 (rank : 20)
Query Neighborhood Hits 30 Target Neighborhood Hits 48 Shared Neighborhood Hits 25
SwissProt Accessions P13861, Q16823 Gene names PRKAR2A, PKR2, PRKAR2
Domain
Architecture
Description cAMP-dependent protein kinase type II-alpha regulatory subunit.
KAP3_MOUSE
 
NC score 0.280371 (rank : 13) θ value θ > 10 (rank : 42)
Query Neighborhood Hits 30 Target Neighborhood Hits 43 Shared Neighborhood Hits 28
SwissProt Accessions P31324, Q3UTZ1, Q80ZM4, Q8BRZ7 Gene names Prkar2b
Domain
Architecture

No domain graphic available

Description cAMP-dependent protein kinase type II-beta regulatory subunit.
KAP3_HUMAN
 
NC score 0.276875 (rank : 14) θ value θ > 10 (rank : 41)
Query Neighborhood Hits 30 Target Neighborhood Hits 40 Shared Neighborhood Hits 28
SwissProt Accessions P31323 Gene names PRKAR2B
Domain
Architecture
Description cAMP-dependent protein kinase type II-beta regulatory subunit.
RPGF6_HUMAN
 
NC score 0.214281 (rank : 15) θ value 0.000602161 (rank : 12)
Query Neighborhood Hits 30 Target Neighborhood Hits 266 Shared Neighborhood Hits 15
SwissProt Accessions Q8TEU7, Q8NI21, Q8TEU6, Q96PC1 Gene names RAPGEF6, PDZGEF2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).
RPGF5_MOUSE
 
NC score 0.193876 (rank : 16) θ value θ > 10 (rank : 46)
Query Neighborhood Hits 30 Target Neighborhood Hits 85 Shared Neighborhood Hits 6
SwissProt Accessions Q8C0Q9, Q8BJJ9, Q8C0R5 Gene names Rapgef5, Gfr, Kiaa0277, Mrgef
Domain
Architecture
Description Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).
RPGF5_HUMAN
 
NC score 0.192195 (rank : 17) θ value θ > 10 (rank : 45)
Query Neighborhood Hits 30 Target Neighborhood Hits 42 Shared Neighborhood Hits 6
SwissProt Accessions Q92565, Q8IXU5 Gene names RAPGEF5, GFR, KIAA0277, MRGEF
Domain
Architecture
Description Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).
RPGF2_HUMAN
 
NC score 0.189305 (rank : 18) θ value 0.00665767 (rank : 13)
Query Neighborhood Hits 30 Target Neighborhood Hits 242 Shared Neighborhood Hits 8
SwissProt Accessions Q9Y4G8 Gene names RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain
Architecture

No domain graphic available

Description Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).
CNGB1_HUMAN
 
NC score 0.163867 (rank : 19) θ value 0.0736092 (rank : 21)
Query Neighborhood Hits 30 Target Neighborhood Hits 222 Shared Neighborhood Hits 27
SwissProt Accessions Q14028, Q14029 Gene names CNGB1, CNCG4
Domain
Architecture
Description Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).
CNGB3_HUMAN
 
NC score 0.136701 (rank : 20) θ value 1.81305 (rank : 26)
Query Neighborhood Hits 30 Target Neighborhood Hits 206 Shared Neighborhood Hits 25
SwissProt Accessions Q9NQW8, Q9NRE9 Gene names CNGB3
Domain
Architecture
Description Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).
CNGB3_MOUSE
 
NC score 0.132862 (rank : 21) θ value 6.88961 (rank : 30)
Query Neighborhood Hits 30 Target Neighborhood Hits 74 Shared Neighborhood Hits 26
SwissProt Accessions Q9JJZ9 Gene names Cngb3, Cng6
Domain
Architecture
Description Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).
CNGA2_MOUSE
 
NC score 0.122488 (rank : 22) θ value 0.0330416 (rank : 19)
Query Neighborhood Hits 30 Target Neighborhood Hits 86 Shared Neighborhood Hits 23
SwissProt Accessions Q62398 Gene names Cnga2, Cncg2, Cncg4
Domain
Architecture
Description Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).
CNGA3_HUMAN
 
NC score 0.119001 (rank : 23) θ value 1.06291 (rank : 22)
Query Neighborhood Hits 30 Target Neighborhood Hits 125 Shared Neighborhood Hits 23
SwissProt Accessions Q16281, Q9UP64 Gene names CNGA3, CNCG3
Domain
Architecture
Description Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).
RPGF1_HUMAN
 
NC score 0.118030 (rank : 24) θ value θ > 10 (rank : 44)
Query Neighborhood Hits 30 Target Neighborhood Hits 262 Shared Neighborhood Hits 7
SwissProt Accessions Q13905 Gene names RAPGEF1, GRF2
Domain
Architecture
Description Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).
CNGA3_MOUSE
 
NC score 0.118003 (rank : 25) θ value 1.06291 (rank : 23)
Query Neighborhood Hits 30 Target Neighborhood Hits 84 Shared Neighborhood Hits 23
SwissProt Accessions Q9JJZ8, Q9WV01 Gene names Cnga3, Cng3
Domain
Architecture
Description Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).
KGP1B_HUMAN
 
NC score 0.115975 (rank : 26) θ value 1.80886e-08 (rank : 5)
Query Neighborhood Hits 30 Target Neighborhood Hits 921 Shared Neighborhood Hits 27
SwissProt Accessions P14619 Gene names PRKG1, PRKG1B, PRKGR1B
Domain
Architecture
Description cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).
CNGA1_HUMAN
 
NC score 0.115950 (rank : 27) θ value 1.38821 (rank : 24)
Query Neighborhood Hits 30 Target Neighborhood Hits 149 Shared Neighborhood Hits 25
SwissProt Accessions P29973, Q16279, Q16485 Gene names CNGA1, CNCG, CNCG1
Domain
Architecture
Description cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).
KGP1A_HUMAN
 
NC score 0.115544 (rank : 28) θ value 1.80886e-08 (rank : 4)
Query Neighborhood Hits 30 Target Neighborhood Hits 901 Shared Neighborhood Hits 27
SwissProt Accessions Q13976 Gene names PRKG1, PRKGR1A
Domain
Architecture
Description cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).
CNGA1_MOUSE
 
NC score 0.114275 (rank : 29) θ value 1.38821 (rank : 25)
Query Neighborhood Hits 30 Target Neighborhood Hits 198 Shared Neighborhood Hits 25
SwissProt Accessions P29974, Q60776 Gene names Cnga1, Cncg, Cncg1
Domain
Architecture
Description cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).
KGP1B_MOUSE
 
NC score 0.114055 (rank : 30) θ value 1.17247e-07 (rank : 9)
Query Neighborhood Hits 30 Target Neighborhood Hits 922 Shared Neighborhood Hits 27
SwissProt Accessions Q9Z0Z0 Gene names Prkg1, Prkg1b, Prkgr1b
Domain
Architecture
Description cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).
KGP2_MOUSE
 
NC score 0.113675 (rank : 31) θ value 2.21117e-06 (rank : 11)
Query Neighborhood Hits 30 Target Neighborhood Hits 1029 Shared Neighborhood Hits 27
SwissProt Accessions Q61410 Gene names Prkg2, Prkgr2
Domain
Architecture
Description cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).
KGP2_HUMAN
 
NC score 0.113533 (rank : 32) θ value 2.21117e-06 (rank : 10)
Query Neighborhood Hits 30 Target Neighborhood Hits 1023 Shared Neighborhood Hits 27
SwissProt Accessions Q13237, O00125, O60916 Gene names PRKG2, PRKGR2
Domain
Architecture
Description cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).
HCN4_MOUSE
 
NC score 0.097353 (rank : 33) θ value 3.0926 (rank : 28)
Query Neighborhood Hits 30 Target Neighborhood Hits 284 Shared Neighborhood Hits 23
SwissProt Accessions O70507 Gene names Hcn4, Bcng3
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).
HCN4_HUMAN
 
NC score 0.095929 (rank : 34) θ value 3.0926 (rank : 27)
Query Neighborhood Hits 30 Target Neighborhood Hits 303 Shared Neighborhood Hits 23
SwissProt Accessions Q9Y3Q4, Q9UMQ7 Gene names HCN4
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.
HCN2_MOUSE
 
NC score 0.092206 (rank : 35) θ value θ > 10 (rank : 38)
Query Neighborhood Hits 30 Target Neighborhood Hits 278 Shared Neighborhood Hits 24
SwissProt Accessions O88703, O70506 Gene names Hcn2, Bcng2, Hac1
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).
HCN2_HUMAN
 
NC score 0.090954 (rank : 36) θ value θ > 10 (rank : 37)
Query Neighborhood Hits 30 Target Neighborhood Hits 369 Shared Neighborhood Hits 24
SwissProt Accessions Q9UL51, O60742, O60743, O75267, Q9UBS2 Gene names HCN2, BCNG2
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).
HCN3_MOUSE
 
NC score 0.082235 (rank : 37) θ value θ > 10 (rank : 40)
Query Neighborhood Hits 30 Target Neighborhood Hits 112 Shared Neighborhood Hits 22
SwissProt Accessions O88705 Gene names Hcn3, Hac3
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).
HCN3_HUMAN
 
NC score 0.082055 (rank : 38) θ value θ > 10 (rank : 39)
Query Neighborhood Hits 30 Target Neighborhood Hits 99 Shared Neighborhood Hits 22
SwissProt Accessions Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2 Gene names HCN3, KIAA1535
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
HCN1_HUMAN
 
NC score 0.081805 (rank : 39) θ value θ > 10 (rank : 35)
Query Neighborhood Hits 30 Target Neighborhood Hits 120 Shared Neighborhood Hits 22
SwissProt Accessions O60741 Gene names HCN1, BCNG1
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).
HCN1_MOUSE
 
NC score 0.081147 (rank : 40) θ value θ > 10 (rank : 36)
Query Neighborhood Hits 30 Target Neighborhood Hits 172 Shared Neighborhood Hits 22
SwissProt Accessions O88704, O54899, Q9D613 Gene names Hcn1, Bcng1, Hac2
Domain
Architecture
Description Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).
GRP3_HUMAN
 
NC score 0.079720 (rank : 41) θ value θ > 10 (rank : 34)
Query Neighborhood Hits 30 Target Neighborhood Hits 131 Shared Neighborhood Hits 6
SwissProt Accessions Q8IV61, O94931 Gene names RASGRP3, GRP3, KIAA0846
Domain
Architecture
Description RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).
GNRP_HUMAN
 
NC score 0.070828 (rank : 42) θ value θ > 10 (rank : 32)
Query Neighborhood Hits 30 Target Neighborhood Hits 239 Shared Neighborhood Hits 6
SwissProt Accessions Q13972, Q16027 Gene names RASGRF1, CDC25
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).
GNRP_MOUSE
 
NC score 0.069171 (rank : 43) θ value θ > 10 (rank : 33)
Query Neighborhood Hits 30 Target Neighborhood Hits 191 Shared Neighborhood Hits 6
SwissProt Accessions P27671 Gene names Rasgrf1, Cdc25, Grf1
Domain
Architecture
Description Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).
SOS2_HUMAN
 
NC score 0.068958 (rank : 44) θ value θ > 10 (rank : 49)
Query Neighborhood Hits 30 Target Neighborhood Hits 193 Shared Neighborhood Hits 6
SwissProt Accessions Q07890, Q15503 Gene names SOS2
Domain
Architecture
Description Son of sevenless homolog 2 (SOS-2).
SOS1_HUMAN
 
NC score 0.068097 (rank : 45) θ value θ > 10 (rank : 47)
Query Neighborhood Hits 30 Target Neighborhood Hits 274 Shared Neighborhood Hits 6
SwissProt Accessions Q07889 Gene names SOS1
Domain
Architecture
Description Son of sevenless homolog 1 (SOS-1).
SOS1_MOUSE
 
NC score 0.067736 (rank : 46) θ value θ > 10 (rank : 48)
Query Neighborhood Hits 30 Target Neighborhood Hits 281 Shared Neighborhood Hits 6
SwissProt Accessions Q62245, Q62244 Gene names Sos1
Domain
Architecture
Description Son of sevenless homolog 1 (SOS-1) (mSOS-1).
RGL1_HUMAN
 
NC score 0.052009 (rank : 47) θ value θ > 10 (rank : 43)
Query Neighborhood Hits 30 Target Neighborhood Hits 43 Shared Neighborhood Hits 6
SwissProt Accessions Q9NZL6, Q9HBY3, Q9HBY4, Q9NZL5, Q9UG43, Q9Y2G6 Gene names RGL1, KIAA0959, RGL
Domain
Architecture
Description Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).
GNDS_MOUSE
 
NC score 0.051841 (rank : 48) θ value θ > 10 (rank : 31)
Query Neighborhood Hits 30 Target Neighborhood Hits 115 Shared Neighborhood Hits 6
SwissProt Accessions Q03385 Gene names Ralgds, Rgds
Domain
Architecture
Description Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).
SI1L2_HUMAN
 
NC score 0.019960 (rank : 49) θ value 5.27518 (rank : 29)
Query Neighborhood Hits 30 Target Neighborhood Hits 131 Shared Neighborhood Hits 4
SwissProt Accessions Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6 Gene names SIPA1L2, KIAA1389
Domain
Architecture

No domain graphic available

Description Signal-induced proliferation-associated 1-like protein 2.