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Network neighborhood for query Sequence : CNGA1_MOUSE

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CNGA1_MOUSE
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CNGA1_HUMAN
θ value	0 (rank : 1)	NC score	0.992417 (rank : 2)
Query Neighborhood Hits	198	Target Neighborhood Hits	149	Shared Neighborhood Hits	114
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	198	Target Neighborhood Hits	198	Shared Neighborhood Hits	198
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	0 (rank : 3)	NC score	0.982842 (rank : 5)
Query Neighborhood Hits	198	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_HUMAN
θ value	0 (rank : 4)	NC score	0.984106 (rank : 4)
Query Neighborhood Hits	198	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	0 (rank : 5)	NC score	0.985341 (rank : 3)
Query Neighborhood Hits	198	Target Neighborhood Hits	84	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB1_HUMAN
θ value	2.0926e-81 (rank : 6)	NC score	0.925491 (rank : 8)
Query Neighborhood Hits	198	Target Neighborhood Hits	222	Shared Neighborhood Hits	61
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
θ value	2.0926e-81 (rank : 7)	NC score	0.930225 (rank : 7)
Query Neighborhood Hits	198	Target Neighborhood Hits	206	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	2.82823e-78 (rank : 8)	NC score	0.938060 (rank : 6)
Query Neighborhood Hits	198	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

HCN1_HUMAN
θ value	2.04573e-44 (rank : 9)	NC score	0.856005 (rank : 9)
Query Neighborhood Hits	198	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	2.67181e-44 (rank : 10)	NC score	0.852750 (rank : 10)
Query Neighborhood Hits	198	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN4_HUMAN
θ value	3.48949e-44 (rank : 11)	NC score	0.836030 (rank : 14)
Query Neighborhood Hits	198	Target Neighborhood Hits	303	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	1.01529e-43 (rank : 12)	NC score	0.834307 (rank : 15)
Query Neighborhood Hits	198	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_MOUSE
θ value	1.12253e-42 (rank : 13)	NC score	0.838471 (rank : 13)
Query Neighborhood Hits	198	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN2_HUMAN
θ value	9.50281e-42 (rank : 14)	NC score	0.828413 (rank : 16)
Query Neighborhood Hits	198	Target Neighborhood Hits	369	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN3_HUMAN
θ value	6.15952e-41 (rank : 15)	NC score	0.850961 (rank : 12)
Query Neighborhood Hits	198	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	1.3722e-40 (rank : 16)	NC score	0.851691 (rank : 11)
Query Neighborhood Hits	198	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

KCNH7_MOUSE
θ value	1.57e-36 (rank : 17)	NC score	0.808835 (rank : 17)
Query Neighborhood Hits	198	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
θ value	2.26708e-35 (rank : 18)	NC score	0.808139 (rank : 18)
Query Neighborhood Hits	198	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH4_HUMAN
θ value	1.12514e-34 (rank : 19)	NC score	0.805134 (rank : 21)
Query Neighborhood Hits	198	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH7_HUMAN
θ value	7.29293e-34 (rank : 20)	NC score	0.804020 (rank : 22)
Query Neighborhood Hits	198	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH8_HUMAN
θ value	9.52487e-34 (rank : 21)	NC score	0.803774 (rank : 23)
Query Neighborhood Hits	198	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH2_HUMAN
θ value	2.12192e-33 (rank : 22)	NC score	0.807246 (rank : 19)
Query Neighborhood Hits	198	Target Neighborhood Hits	158	Shared Neighborhood Hits	42
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	2.12192e-33 (rank : 23)	NC score	0.806974 (rank : 20)
Query Neighborhood Hits	198	Target Neighborhood Hits	165	Shared Neighborhood Hits	40
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH3_MOUSE
θ value	1.37539e-32 (rank : 24)	NC score	0.793841 (rank : 26)
Query Neighborhood Hits	198	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
θ value	1.52067e-31 (rank : 25)	NC score	0.793801 (rank : 27)
Query Neighborhood Hits	198	Target Neighborhood Hits	148	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH5_HUMAN
θ value	2.59387e-31 (rank : 26)	NC score	0.796239 (rank : 25)
Query Neighborhood Hits	198	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	7.54701e-31 (rank : 27)	NC score	0.796255 (rank : 24)
Query Neighborhood Hits	198	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_HUMAN
θ value	4.89182e-30 (rank : 28)	NC score	0.791882 (rank : 29)
Query Neighborhood Hits	198	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	4.89182e-30 (rank : 29)	NC score	0.792168 (rank : 28)
Query Neighborhood Hits	198	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

ELOA1_HUMAN
θ value	0.000121331 (rank : 30)	NC score	0.058280 (rank : 60)
Query Neighborhood Hits	198	Target Neighborhood Hits	388	Shared Neighborhood Hits	35
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

KGP2_HUMAN
θ value	0.00102713 (rank : 31)	NC score	0.069478 (rank : 44)
Query Neighborhood Hits	198	Target Neighborhood Hits	1023	Shared Neighborhood Hits	69
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
θ value	0.00102713 (rank : 32)	NC score	0.069171 (rank : 45)
Query Neighborhood Hits	198	Target Neighborhood Hits	1029	Shared Neighborhood Hits	68
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP1B_MOUSE
θ value	0.00390308 (rank : 33)	NC score	0.071028 (rank : 41)
Query Neighborhood Hits	198	Target Neighborhood Hits	922	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
θ value	0.00509761 (rank : 34)	NC score	0.070444 (rank : 43)
Query Neighborhood Hits	198	Target Neighborhood Hits	901	Shared Neighborhood Hits	54
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.070747 (rank : 42)
Query Neighborhood Hits	198	Target Neighborhood Hits	921	Shared Neighborhood Hits	55
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

MPP8_HUMAN
θ value	0.00509761 (rank : 36)	NC score	0.037427 (rank : 79)
Query Neighborhood Hits	198	Target Neighborhood Hits	948	Shared Neighborhood Hits	78
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SMC4_MOUSE
θ value	0.0148317 (rank : 37)	NC score	0.064748 (rank : 51)
Query Neighborhood Hits	198	Target Neighborhood Hits	830	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

NASP_HUMAN
θ value	0.0193708 (rank : 38)	NC score	0.063863 (rank : 53)
Query Neighborhood Hits	198	Target Neighborhood Hits	709	Shared Neighborhood Hits	63
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ERCC6_HUMAN
θ value	0.0330416 (rank : 39)	NC score	0.021242 (rank : 138)
Query Neighborhood Hits	198	Target Neighborhood Hits	247	Shared Neighborhood Hits	28
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

KAP1_HUMAN
θ value	0.0330416 (rank : 40)	NC score	0.233776 (rank : 31)
Query Neighborhood Hits	198	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

SMC4_HUMAN
θ value	0.0330416 (rank : 41)	NC score	0.059478 (rank : 58)
Query Neighborhood Hits	198	Target Neighborhood Hits	937	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

LEO1_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.049697 (rank : 64)
Query Neighborhood Hits	198	Target Neighborhood Hits	958	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	0.0563607 (rank : 43)	NC score	0.046952 (rank : 67)
Query Neighborhood Hits	198	Target Neighborhood Hits	946	Shared Neighborhood Hits	59
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

KAP1_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.228199 (rank : 33)
Query Neighborhood Hits	198	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP3_HUMAN
θ value	0.0736092 (rank : 45)	NC score	0.196627 (rank : 35)
Query Neighborhood Hits	198	Target Neighborhood Hits	40	Shared Neighborhood Hits	32
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	0.0736092 (rank : 46)	NC score	0.202387 (rank : 34)
Query Neighborhood Hits	198	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

PPIG_HUMAN
θ value	0.0961366 (rank : 47)	NC score	0.039187 (rank : 75)
Query Neighborhood Hits	198	Target Neighborhood Hits	670	Shared Neighborhood Hits	84
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TRPM6_MOUSE
θ value	0.0961366 (rank : 48)	NC score	0.020231 (rank : 145)
Query Neighborhood Hits	198	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

BAZ1B_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.028944 (rank : 95)
Query Neighborhood Hits	198	Target Neighborhood Hits	701	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

ITPR3_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.016479 (rank : 169)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

KAP0_HUMAN
θ value	0.125558 (rank : 51)	NC score	0.249528 (rank : 30)
Query Neighborhood Hits	198	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP2_MOUSE
θ value	0.125558 (rank : 52)	NC score	0.191319 (rank : 36)
Query Neighborhood Hits	198	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

RBBP6_HUMAN
θ value	0.125558 (rank : 53)	NC score	0.047131 (rank : 66)
Query Neighborhood Hits	198	Target Neighborhood Hits	1135	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

IP6K2_MOUSE
θ value	0.163984 (rank : 54)	NC score	0.018929 (rank : 155)
Query Neighborhood Hits	198	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q80V72	Gene names	Ihpk2, Ip6k2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

KAP0_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.232181 (rank : 32)
Query Neighborhood Hits	198	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP2_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.188220 (rank : 37)
Query Neighborhood Hits	198	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

SLK_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.011937 (rank : 193)
Query Neighborhood Hits	198	Target Neighborhood Hits	1798	Shared Neighborhood Hits	78
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

ANR12_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.029214 (rank : 93)
Query Neighborhood Hits	198	Target Neighborhood Hits	1081	Shared Neighborhood Hits	89
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

DMN_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.021294 (rank : 137)
Query Neighborhood Hits	198	Target Neighborhood Hits	690	Shared Neighborhood Hits	55
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

OXR1_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.032937 (rank : 87)
Query Neighborhood Hits	198	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

SLK_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.011884 (rank : 195)
Query Neighborhood Hits	198	Target Neighborhood Hits	1775	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

AFF4_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.041112 (rank : 71)
Query Neighborhood Hits	198	Target Neighborhood Hits	611	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	0.279714 (rank : 63)	NC score	0.038916 (rank : 76)
Query Neighborhood Hits	198	Target Neighborhood Hits	581	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

PHF20_HUMAN
θ value	0.279714 (rank : 64)	NC score	0.051869 (rank : 63)
Query Neighborhood Hits	198	Target Neighborhood Hits	394	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SFRIP_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.034219 (rank : 84)
Query Neighborhood Hits	198	Target Neighborhood Hits	530	Shared Neighborhood Hits	33
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CCD55_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.037981 (rank : 77)
Query Neighborhood Hits	198	Target Neighborhood Hits	513	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

JHD1B_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.017137 (rank : 168)
Query Neighborhood Hits	198	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

MATR3_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.045469 (rank : 68)
Query Neighborhood Hits	198	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
θ value	0.365318 (rank : 69)	NC score	0.044897 (rank : 69)
Query Neighborhood Hits	198	Target Neighborhood Hits	321	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

RIF1_MOUSE
θ value	0.365318 (rank : 70)	NC score	0.026076 (rank : 114)
Query Neighborhood Hits	198	Target Neighborhood Hits	315	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

WDR47_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.016144 (rank : 170)
Query Neighborhood Hits	198	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

SHOC2_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.003420 (rank : 205)
Query Neighborhood Hits	198	Target Neighborhood Hits	330	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ13, O76063	Gene names	SHOC2, KIAA0862
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

LUZP1_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.029433 (rank : 92)
Query Neighborhood Hits	198	Target Neighborhood Hits	940	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

PHF20_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.047502 (rank : 65)
Query Neighborhood Hits	198	Target Neighborhood Hits	513	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CAB45_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.018782 (rank : 156)
Query Neighborhood Hits	198	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRK5, Q8NBQ3, Q9NZP7	Gene names	SDF4, CAB45
Domain Architecture
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

MYH2_HUMAN
θ value	0.813845 (rank : 76)	NC score	0.026871 (rank : 106)
Query Neighborhood Hits	198	Target Neighborhood Hits	1491	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

RPGF3_MOUSE
θ value	0.813845 (rank : 77)	NC score	0.065149 (rank : 49)
Query Neighborhood Hits	198	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

SDCG1_MOUSE
θ value	0.813845 (rank : 78)	NC score	0.031337 (rank : 89)
Query Neighborhood Hits	198	Target Neighborhood Hits	168	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

XLKD1_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.018250 (rank : 161)
Query Neighborhood Hits	198	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

CROCC_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.023581 (rank : 128)
Query Neighborhood Hits	198	Target Neighborhood Hits	1409	Shared Neighborhood Hits	67
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MYH7_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.027988 (rank : 98)
Query Neighborhood Hits	198	Target Neighborhood Hits	1559	Shared Neighborhood Hits	76
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RPGF3_HUMAN
θ value	1.06291 (rank : 82)	NC score	0.058551 (rank : 59)
Query Neighborhood Hits	198	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

C8AP2_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.042901 (rank : 70)
Query Neighborhood Hits	198	Target Neighborhood Hits	548	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CT152_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.114275 (rank : 39)
Query Neighborhood Hits	198	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

GASP1_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.015712 (rank : 173)
Query Neighborhood Hits	198	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

KCNQ4_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.023745 (rank : 127)
Query Neighborhood Hits	198	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

LARP1_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.036071 (rank : 82)
Query Neighborhood Hits	198	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

MYH1_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.028538 (rank : 97)
Query Neighborhood Hits	198	Target Neighborhood Hits	1461	Shared Neighborhood Hits	77
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.027819 (rank : 99)
Query Neighborhood Hits	198	Target Neighborhood Hits	1476	Shared Neighborhood Hits	76
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	1.38821 (rank : 90)	NC score	0.026978 (rank : 104)
Query Neighborhood Hits	198	Target Neighborhood Hits	1426	Shared Neighborhood Hits	72
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NP1L3_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.025774 (rank : 119)
Query Neighborhood Hits	198	Target Neighborhood Hits	172	Shared Neighborhood Hits	35
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

SMC1A_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.032856 (rank : 88)
Query Neighborhood Hits	198	Target Neighborhood Hits	1346	Shared Neighborhood Hits	84
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.033072 (rank : 86)
Query Neighborhood Hits	198	Target Neighborhood Hits	1384	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.034450 (rank : 83)
Query Neighborhood Hits	198	Target Neighborhood Hits	1405	Shared Neighborhood Hits	82
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

ARI5B_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.025717 (rank : 120)
Query Neighborhood Hits	198	Target Neighborhood Hits	328	Shared Neighborhood Hits	26
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ASXL1_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.017414 (rank : 166)
Query Neighborhood Hits	198	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CCD39_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.025785 (rank : 118)
Query Neighborhood Hits	198	Target Neighborhood Hits	1026	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CJ078_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.026588 (rank : 108)
Query Neighborhood Hits	198	Target Neighborhood Hits	559	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

JHD1B_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.014982 (rank : 179)
Query Neighborhood Hits	198	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MYH1_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.027131 (rank : 102)
Query Neighborhood Hits	198	Target Neighborhood Hits	1478	Shared Neighborhood Hits	75
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH6_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.026878 (rank : 105)
Query Neighborhood Hits	198	Target Neighborhood Hits	1501	Shared Neighborhood Hits	75
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SETD8_MOUSE
θ value	1.81305 (rank : 102)	NC score	0.026586 (rank : 109)
Query Neighborhood Hits	198	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SYCP1_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.027363 (rank : 101)
Query Neighborhood Hits	198	Target Neighborhood Hits	1313	Shared Neighborhood Hits	80
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TE2IP_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.022142 (rank : 133)
Query Neighborhood Hits	198	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

TXND2_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.036737 (rank : 81)
Query Neighborhood Hits	198	Target Neighborhood Hits	828	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ADA30_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.004919 (rank : 203)
Query Neighborhood Hits	198	Target Neighborhood Hits	391	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CT152_MOUSE
θ value	2.36792 (rank : 107)	NC score	0.149528 (rank : 38)
Query Neighborhood Hits	198	Target Neighborhood Hits	38	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

MCPH1_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.013531 (rank : 186)
Query Neighborhood Hits	198	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

MYH8_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.027598 (rank : 100)
Query Neighborhood Hits	198	Target Neighborhood Hits	1610	Shared Neighborhood Hits	86
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PRGC1_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.019306 (rank : 153)
Query Neighborhood Hits	198	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

SYNC_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.018459 (rank : 159)
Query Neighborhood Hits	198	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

ZFP37_MOUSE
θ value	2.36792 (rank : 112)	NC score	-0.003628 (rank : 209)
Query Neighborhood Hits	198	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

DMD_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.020263 (rank : 144)
Query Neighborhood Hits	198	Target Neighborhood Hits	1135	Shared Neighborhood Hits	63
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ELOA1_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.037093 (rank : 80)
Query Neighborhood Hits	198	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

LRMP_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.018303 (rank : 160)
Query Neighborhood Hits	198	Target Neighborhood Hits	126	Shared Neighborhood Hits	22
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

MRCKB_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.015432 (rank : 178)
Query Neighborhood Hits	198	Target Neighborhood Hits	2180	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NEST_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.023975 (rank : 126)
Query Neighborhood Hits	198	Target Neighborhood Hits	1305	Shared Neighborhood Hits	81
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NPBL_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.033468 (rank : 85)
Query Neighborhood Hits	198	Target Neighborhood Hits	1041	Shared Neighborhood Hits	76
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSBP1_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.040592 (rank : 72)
Query Neighborhood Hits	198	Target Neighborhood Hits	681	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RFC1_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.020829 (rank : 143)
Query Neighborhood Hits	198	Target Neighborhood Hits	352	Shared Neighborhood Hits	38
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

SETD8_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.018231 (rank : 162)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

AHTF1_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.015512 (rank : 177)
Query Neighborhood Hits	198	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CI039_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.025803 (rank : 117)
Query Neighborhood Hits	198	Target Neighborhood Hits	1171	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

FBX41_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.020917 (rank : 142)
Query Neighborhood Hits	198	Target Neighborhood Hits	475	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.020924 (rank : 141)
Query Neighborhood Hits	198	Target Neighborhood Hits	430	Shared Neighborhood Hits	44
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

GOGB1_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.026528 (rank : 110)
Query Neighborhood Hits	198	Target Neighborhood Hits	2297	Shared Neighborhood Hits	103
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HMMR_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.031041 (rank : 90)
Query Neighborhood Hits	198	Target Neighborhood Hits	1178	Shared Neighborhood Hits	72
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

INP4B_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.012112 (rank : 192)
Query Neighborhood Hits	198	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	O15327, Q6IN59, Q6PJB4	Gene names	INPP4B
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

K0552_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.017486 (rank : 165)
Query Neighborhood Hits	198	Target Neighborhood Hits	442	Shared Neighborhood Hits	41
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

MRCKB_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.015605 (rank : 175)
Query Neighborhood Hits	198	Target Neighborhood Hits	2239	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MY18A_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.024817 (rank : 122)
Query Neighborhood Hits	198	Target Neighborhood Hits	1989	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH14_MOUSE
θ value	4.03905 (rank : 132)	NC score	0.026988 (rank : 103)
Query Neighborhood Hits	198	Target Neighborhood Hits	1225	Shared Neighborhood Hits	74
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYRIP_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.026418 (rank : 111)
Query Neighborhood Hits	198	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NIPBL_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.037736 (rank : 78)
Query Neighborhood Hits	198	Target Neighborhood Hits	1311	Shared Neighborhood Hits	90
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SEC63_MOUSE
θ value	4.03905 (rank : 135)	NC score	0.011913 (rank : 194)
Query Neighborhood Hits	198	Target Neighborhood Hits	601	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

STK10_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.014468 (rank : 180)
Query Neighborhood Hits	198	Target Neighborhood Hits	2132	Shared Neighborhood Hits	93
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TAF4_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.012891 (rank : 188)
Query Neighborhood Hits	198	Target Neighborhood Hits	687	Shared Neighborhood Hits	31
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TRI63_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.006553 (rank : 202)
Query Neighborhood Hits	198	Target Neighborhood Hits	298	Shared Neighborhood Hits	22
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

ZN292_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.018000 (rank : 164)
Query Neighborhood Hits	198	Target Neighborhood Hits	918	Shared Neighborhood Hits	42
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

CAB45_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.013848 (rank : 182)
Query Neighborhood Hits	198	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q61112, Q61113	Gene names	Sdf4, Cab45
Domain Architecture	No domain graphic available
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

CF060_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.021955 (rank : 134)
Query Neighborhood Hits	198	Target Neighborhood Hits	1270	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DNJC8_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.015664 (rank : 174)
Query Neighborhood Hits	198	Target Neighborhood Hits	380	Shared Neighborhood Hits	33
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.015871 (rank : 172)
Query Neighborhood Hits	198	Target Neighborhood Hits	392	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

MY18A_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.025531 (rank : 121)
Query Neighborhood Hits	198	Target Neighborhood Hits	1929	Shared Neighborhood Hits	89
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH13_HUMAN
θ value	5.27518 (rank : 145)	NC score	0.025945 (rank : 116)
Query Neighborhood Hits	198	Target Neighborhood Hits	1504	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH8_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.026248 (rank : 112)
Query Neighborhood Hits	198	Target Neighborhood Hits	1600	Shared Neighborhood Hits	83
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYRIP_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.021558 (rank : 135)
Query Neighborhood Hits	198	Target Neighborhood Hits	207	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NFH_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.030570 (rank : 91)
Query Neighborhood Hits	198	Target Neighborhood Hits	2247	Shared Neighborhood Hits	114
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NKTR_HUMAN
θ value	5.27518 (rank : 149)	NC score	0.026056 (rank : 115)
Query Neighborhood Hits	198	Target Neighborhood Hits	658	Shared Neighborhood Hits	55
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PACN2_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.013755 (rank : 184)
Query Neighborhood Hits	198	Target Neighborhood Hits	382	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PARP1_MOUSE
θ value	5.27518 (rank : 151)	NC score	0.010194 (rank : 199)
Query Neighborhood Hits	198	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PHF3_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.020005 (rank : 147)
Query Neighborhood Hits	198	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

TR150_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.022906 (rank : 130)
Query Neighborhood Hits	198	Target Neighborhood Hits	468	Shared Neighborhood Hits	52
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ZCPW1_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.019643 (rank : 150)
Query Neighborhood Hits	198	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

AKAP2_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.012319 (rank : 191)
Query Neighborhood Hits	198	Target Neighborhood Hits	507	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

CCD39_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.024414 (rank : 123)
Query Neighborhood Hits	198	Target Neighborhood Hits	868	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CJ006_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.018488 (rank : 158)
Query Neighborhood Hits	198	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

DMD_MOUSE
θ value	6.88961 (rank : 158)	NC score	0.019440 (rank : 152)
Query Neighborhood Hits	198	Target Neighborhood Hits	1111	Shared Neighborhood Hits	61
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

EEA1_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.020039 (rank : 146)
Query Neighborhood Hits	198	Target Neighborhood Hits	1637	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

IF4E3_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.007714 (rank : 200)
Query Neighborhood Hits	198	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O60573, O75349	Gene names	EIF4EL3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (Eukaryotic translation initiation factor 4E homologous protein) (mRNA cap-binding protein 4EHP) (eIF4E-like protein 4E-LP).

KCNQ3_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.039341 (rank : 74)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.039634 (rank : 73)
Query Neighborhood Hits	198	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ5_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.014364 (rank : 181)
Query Neighborhood Hits	198	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

MBB1A_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.013090 (rank : 187)
Query Neighborhood Hits	198	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

MEPE_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.013532 (rank : 185)
Query Neighborhood Hits	198	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

MLL3_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.021094 (rank : 139)
Query Neighborhood Hits	198	Target Neighborhood Hits	1644	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MO4L2_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.010943 (rank : 196)
Query Neighborhood Hits	198	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

NFH_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.022677 (rank : 131)
Query Neighborhood Hits	198	Target Neighborhood Hits	1242	Shared Neighborhood Hits	113
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOP14_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.021538 (rank : 136)
Query Neighborhood Hits	198	Target Neighborhood Hits	324	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PEPL_MOUSE
θ value	6.88961 (rank : 170)	NC score	0.017338 (rank : 167)
Query Neighborhood Hits	198	Target Neighborhood Hits	1105	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RRP5_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.020001 (rank : 148)
Query Neighborhood Hits	198	Target Neighborhood Hits	291	Shared Neighborhood Hits	40
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

SMC2_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.029106 (rank : 94)
Query Neighborhood Hits	198	Target Neighborhood Hits	1131	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ANR18_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.013772 (rank : 183)
Query Neighborhood Hits	198	Target Neighborhood Hits	1106	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASXL1_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.019536 (rank : 151)
Query Neighborhood Hits	198	Target Neighborhood Hits	182	Shared Neighborhood Hits	15
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BCLF1_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.019046 (rank : 154)
Query Neighborhood Hits	198	Target Neighborhood Hits	298	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BPAEA_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.020983 (rank : 140)
Query Neighborhood Hits	198	Target Neighborhood Hits	1369	Shared Neighborhood Hits	68
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DOCK8_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.003030 (rank : 206)
Query Neighborhood Hits	198	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

FOXN3_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.001664 (rank : 208)
Query Neighborhood Hits	198	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

ICAL_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.015559 (rank : 176)
Query Neighborhood Hits	198	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ITSN1_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.012848 (rank : 189)
Query Neighborhood Hits	198	Target Neighborhood Hits	1757	Shared Neighborhood Hits	81
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KCNQ2_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.024297 (rank : 124)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.023422 (rank : 129)
Query Neighborhood Hits	198	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

MYH3_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.028917 (rank : 96)
Query Neighborhood Hits	198	Target Neighborhood Hits	1660	Shared Neighborhood Hits	82
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NKTR_MOUSE
θ value	8.99809 (rank : 184)	NC score	0.018617 (rank : 157)
Query Neighborhood Hits	198	Target Neighborhood Hits	417	Shared Neighborhood Hits	43
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

OTU6B_MOUSE
θ value	8.99809 (rank : 185)	NC score	0.015995 (rank : 171)
Query Neighborhood Hits	198	Target Neighborhood Hits	202	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

PACN2_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.007283 (rank : 201)
Query Neighborhood Hits	198	Target Neighborhood Hits	339	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PSMD2_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.012462 (rank : 190)
Query Neighborhood Hits	198	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

RRBP1_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.024253 (rank : 125)
Query Neighborhood Hits	198	Target Neighborhood Hits	1650	Shared Neighborhood Hits	89
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SAS6_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.019659 (rank : 149)
Query Neighborhood Hits	198	Target Neighborhood Hits	791	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SMP1L_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.002422 (rank : 207)
Query Neighborhood Hits	198	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SYCP1_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.026180 (rank : 113)
Query Neighborhood Hits	198	Target Neighborhood Hits	1456	Shared Neighborhood Hits	86
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TCAL5_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.022349 (rank : 132)
Query Neighborhood Hits	198	Target Neighborhood Hits	806	Shared Neighborhood Hits	52
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TEX14_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.010574 (rank : 197)
Query Neighborhood Hits	198	Target Neighborhood Hits	1103	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TNNT2_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.018078 (rank : 163)
Query Neighborhood Hits	198	Target Neighborhood Hits	395	Shared Neighborhood Hits	45
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TSH1_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.004214 (rank : 204)
Query Neighborhood Hits	198	Target Neighborhood Hits	675	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

TTF2_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.010214 (rank : 198)
Query Neighborhood Hits	198	Target Neighborhood Hits	364	Shared Neighborhood Hits	24
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

WDR60_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.026869 (rank : 107)
Query Neighborhood Hits	198	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZKSC1_HUMAN
θ value	8.99809 (rank : 198)	NC score	-0.003981 (rank : 210)
Query Neighborhood Hits	198	Target Neighborhood Hits	949	Shared Neighborhood Hits	24
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

KCNK2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.065423 (rank : 48)
Query Neighborhood Hits	198	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.064986 (rank : 50)
Query Neighborhood Hits	198	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.063223 (rank : 55)
Query Neighborhood Hits	198	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.061361 (rank : 56)
Query Neighborhood Hits	198	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.055383 (rank : 61)
Query Neighborhood Hits	198	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.064111 (rank : 52)
Query Neighborhood Hits	198	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.061043 (rank : 57)
Query Neighborhood Hits	198	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.067437 (rank : 46)
Query Neighborhood Hits	198	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.053700 (rank : 62)
Query Neighborhood Hits	198	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.101609 (rank : 40)
Query Neighborhood Hits	198	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

RPGF4_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.063631 (rank : 54)
Query Neighborhood Hits	198	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.066648 (rank : 47)
Query Neighborhood Hits	198	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

Hits sorted by NC score

CNGA1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	198	Target Neighborhood Hits	198	Shared Neighborhood Hits	198
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.992417 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	198	Target Neighborhood Hits	149	Shared Neighborhood Hits	114
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.985341 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	198	Target Neighborhood Hits	84	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.984106 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	198	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
NC score	0.982842 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	198	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGB3_MOUSE
NC score	0.938060 (rank : 6)	θ value	2.82823e-78 (rank : 8)
Query Neighborhood Hits	198	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.930225 (rank : 7)	θ value	2.0926e-81 (rank : 7)
Query Neighborhood Hits	198	Target Neighborhood Hits	206	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.925491 (rank : 8)	θ value	2.0926e-81 (rank : 6)
Query Neighborhood Hits	198	Target Neighborhood Hits	222	Shared Neighborhood Hits	61
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

HCN1_HUMAN
NC score	0.856005 (rank : 9)	θ value	2.04573e-44 (rank : 9)
Query Neighborhood Hits	198	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.852750 (rank : 10)	θ value	2.67181e-44 (rank : 10)
Query Neighborhood Hits	198	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
NC score	0.851691 (rank : 11)	θ value	1.3722e-40 (rank : 16)
Query Neighborhood Hits	198	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.850961 (rank : 12)	θ value	6.15952e-41 (rank : 15)
Query Neighborhood Hits	198	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.838471 (rank : 13)	θ value	1.12253e-42 (rank : 13)
Query Neighborhood Hits	198	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.836030 (rank : 14)	θ value	3.48949e-44 (rank : 11)
Query Neighborhood Hits	198	Target Neighborhood Hits	303	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.834307 (rank : 15)	θ value	1.01529e-43 (rank : 12)
Query Neighborhood Hits	198	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.828413 (rank : 16)	θ value	9.50281e-42 (rank : 14)
Query Neighborhood Hits	198	Target Neighborhood Hits	369	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCNH7_MOUSE
NC score	0.808835 (rank : 17)	θ value	1.57e-36 (rank : 17)
Query Neighborhood Hits	198	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
NC score	0.808139 (rank : 18)	θ value	2.26708e-35 (rank : 18)
Query Neighborhood Hits	198	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.807246 (rank : 19)	θ value	2.12192e-33 (rank : 22)
Query Neighborhood Hits	198	Target Neighborhood Hits	158	Shared Neighborhood Hits	42
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.806974 (rank : 20)	θ value	2.12192e-33 (rank : 23)
Query Neighborhood Hits	198	Target Neighborhood Hits	165	Shared Neighborhood Hits	40
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH4_HUMAN
NC score	0.805134 (rank : 21)	θ value	1.12514e-34 (rank : 19)
Query Neighborhood Hits	198	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH7_HUMAN
NC score	0.804020 (rank : 22)	θ value	7.29293e-34 (rank : 20)
Query Neighborhood Hits	198	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH8_HUMAN
NC score	0.803774 (rank : 23)	θ value	9.52487e-34 (rank : 21)
Query Neighborhood Hits	198	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH5_MOUSE
NC score	0.796255 (rank : 24)	θ value	7.54701e-31 (rank : 27)
Query Neighborhood Hits	198	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.796239 (rank : 25)	θ value	2.59387e-31 (rank : 26)
Query Neighborhood Hits	198	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH3_MOUSE
NC score	0.793841 (rank : 26)	θ value	1.37539e-32 (rank : 24)
Query Neighborhood Hits	198	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.793801 (rank : 27)	θ value	1.52067e-31 (rank : 25)
Query Neighborhood Hits	198	Target Neighborhood Hits	148	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH1_MOUSE
NC score	0.792168 (rank : 28)	θ value	4.89182e-30 (rank : 29)
Query Neighborhood Hits	198	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.791882 (rank : 29)	θ value	4.89182e-30 (rank : 28)
Query Neighborhood Hits	198	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KAP0_HUMAN
NC score	0.249528 (rank : 30)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	198	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP1_HUMAN
NC score	0.233776 (rank : 31)	θ value	0.0330416 (rank : 40)
Query Neighborhood Hits	198	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP0_MOUSE
NC score	0.232181 (rank : 32)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	198	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_MOUSE
NC score	0.228199 (rank : 33)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	198	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP3_MOUSE
NC score	0.202387 (rank : 34)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	198	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.196627 (rank : 35)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	198	Target Neighborhood Hits	40	Shared Neighborhood Hits	32
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.191319 (rank : 36)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	198	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.188220 (rank : 37)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	198	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

CT152_MOUSE
NC score	0.149528 (rank : 38)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	198	Target Neighborhood Hits	38	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

CT152_HUMAN
NC score	0.114275 (rank : 39)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	198	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNKH_HUMAN
NC score	0.101609 (rank : 40)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	198	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KGP1B_MOUSE
NC score	0.071028 (rank : 41)	θ value	0.00390308 (rank : 33)
Query Neighborhood Hits	198	Target Neighborhood Hits	922	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.070747 (rank : 42)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	198	Target Neighborhood Hits	921	Shared Neighborhood Hits	55
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.070444 (rank : 43)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	198	Target Neighborhood Hits	901	Shared Neighborhood Hits	54
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP2_HUMAN
NC score	0.069478 (rank : 44)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	198	Target Neighborhood Hits	1023	Shared Neighborhood Hits	69
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
NC score	0.069171 (rank : 45)	θ value	0.00102713 (rank : 32)
Query Neighborhood Hits	198	Target Neighborhood Hits	1029	Shared Neighborhood Hits	68
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNKF_HUMAN
NC score	0.067437 (rank : 46)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	198	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

RPGF4_MOUSE
NC score	0.066648 (rank : 47)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	198	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

KCNK2_HUMAN
NC score	0.065423 (rank : 48)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	198	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

RPGF3_MOUSE
NC score	0.065149 (rank : 49)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	198	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

KCNK2_MOUSE
NC score	0.064986 (rank : 50)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	198	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

SMC4_MOUSE
NC score	0.064748 (rank : 51)	θ value	0.0148317 (rank : 37)
Query Neighborhood Hits	198	Target Neighborhood Hits	830	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

KCNK6_HUMAN
NC score	0.064111 (rank : 52)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	198	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

NASP_HUMAN
NC score	0.063863 (rank : 53)	θ value	0.0193708 (rank : 38)
Query Neighborhood Hits	198	Target Neighborhood Hits	709	Shared Neighborhood Hits	63
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RPGF4_HUMAN
NC score	0.063631 (rank : 54)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	198	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

KCNK3_HUMAN
NC score	0.063223 (rank : 55)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	198	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.061361 (rank : 56)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	198	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.061043 (rank : 57)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	198	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

SMC4_HUMAN
NC score	0.059478 (rank : 58)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	198	Target Neighborhood Hits	937	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

RPGF3_HUMAN
NC score	0.058551 (rank : 59)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	198	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

ELOA1_HUMAN
NC score	0.058280 (rank : 60)	θ value	0.000121331 (rank : 30)
Query Neighborhood Hits	198	Target Neighborhood Hits	388	Shared Neighborhood Hits	35
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

KCNK4_HUMAN
NC score	0.055383 (rank : 61)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	198	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.053700 (rank : 62)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	198	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

PHF20_HUMAN
NC score	0.051869 (rank : 63)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	198	Target Neighborhood Hits	394	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

LEO1_HUMAN
NC score	0.049697 (rank : 64)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	198	Target Neighborhood Hits	958	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PHF20_MOUSE
NC score	0.047502 (rank : 65)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	198	Target Neighborhood Hits	513	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

RBBP6_HUMAN
NC score	0.047131 (rank : 66)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	198	Target Neighborhood Hits	1135	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

LEO1_MOUSE
NC score	0.046952 (rank : 67)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	198	Target Neighborhood Hits	946	Shared Neighborhood Hits	59
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MATR3_HUMAN
NC score	0.045469 (rank : 68)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	198	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
NC score	0.044897 (rank : 69)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	198	Target Neighborhood Hits	321	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

C8AP2_HUMAN
NC score	0.042901 (rank : 70)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	198	Target Neighborhood Hits	548	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

AFF4_HUMAN
NC score	0.041112 (rank : 71)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	198	Target Neighborhood Hits	611	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

NSBP1_MOUSE
NC score	0.040592 (rank : 72)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	198	Target Neighborhood Hits	681	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

KCNQ3_MOUSE
NC score	0.039634 (rank : 73)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	198	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.039341 (rank : 74)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

PPIG_HUMAN
NC score	0.039187 (rank : 75)	θ value	0.0961366 (rank : 47)
Query Neighborhood Hits	198	Target Neighborhood Hits	670	Shared Neighborhood Hits	84
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

AFF4_MOUSE
NC score	0.038916 (rank : 76)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	198	Target Neighborhood Hits	581	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CCD55_HUMAN
NC score	0.037981 (rank : 77)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	198	Target Neighborhood Hits	513	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NIPBL_HUMAN
NC score	0.037736 (rank : 78)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	198	Target Neighborhood Hits	1311	Shared Neighborhood Hits	90
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MPP8_HUMAN
NC score	0.037427 (rank : 79)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	198	Target Neighborhood Hits	948	Shared Neighborhood Hits	78
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ELOA1_MOUSE
NC score	0.037093 (rank : 80)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	198	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

TXND2_MOUSE
NC score	0.036737 (rank : 81)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	198	Target Neighborhood Hits	828	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

LARP1_HUMAN
NC score	0.036071 (rank : 82)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	198	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

SMC2_HUMAN
NC score	0.034450 (rank : 83)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	198	Target Neighborhood Hits	1405	Shared Neighborhood Hits	82
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SFRIP_HUMAN
NC score	0.034219 (rank : 84)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	198	Target Neighborhood Hits	530	Shared Neighborhood Hits	33
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

NPBL_MOUSE
NC score	0.033468 (rank : 85)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	198	Target Neighborhood Hits	1041	Shared Neighborhood Hits	76
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SMC1A_MOUSE
NC score	0.033072 (rank : 86)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	198	Target Neighborhood Hits	1384	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

OXR1_HUMAN
NC score	0.032937 (rank : 87)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	198	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

SMC1A_HUMAN
NC score	0.032856 (rank : 88)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	198	Target Neighborhood Hits	1346	Shared Neighborhood Hits	84
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SDCG1_MOUSE
NC score	0.031337 (rank : 89)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	198	Target Neighborhood Hits	168	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

HMMR_MOUSE
NC score	0.031041 (rank : 90)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	198	Target Neighborhood Hits	1178	Shared Neighborhood Hits	72
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

NFH_MOUSE
NC score	0.030570 (rank : 91)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	198	Target Neighborhood Hits	2247	Shared Neighborhood Hits	114
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LUZP1_MOUSE
NC score	0.029433 (rank : 92)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	198	Target Neighborhood Hits	940	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

ANR12_HUMAN
NC score	0.029214 (rank : 93)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	198	Target Neighborhood Hits	1081	Shared Neighborhood Hits	89
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SMC2_MOUSE
NC score	0.029106 (rank : 94)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	198	Target Neighborhood Hits	1131	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

BAZ1B_HUMAN
NC score	0.028944 (rank : 95)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	198	Target Neighborhood Hits	701	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

MYH3_HUMAN
NC score	0.028917 (rank : 96)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	198	Target Neighborhood Hits	1660	Shared Neighborhood Hits	82
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH1_MOUSE
NC score	0.028538 (rank : 97)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	198	Target Neighborhood Hits	1461	Shared Neighborhood Hits	77
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH7_HUMAN
NC score	0.027988 (rank : 98)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	198	Target Neighborhood Hits	1559	Shared Neighborhood Hits	76
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH4_MOUSE
NC score	0.027819 (rank : 99)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	198	Target Neighborhood Hits	1476	Shared Neighborhood Hits	76
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
NC score	0.027598 (rank : 100)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	198	Target Neighborhood Hits	1610	Shared Neighborhood Hits	86
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SYCP1_HUMAN
NC score	0.027363 (rank : 101)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	198	Target Neighborhood Hits	1313	Shared Neighborhood Hits	80
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MYH1_HUMAN
NC score	0.027131 (rank : 102)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	198	Target Neighborhood Hits	1478	Shared Neighborhood Hits	75
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH14_MOUSE
NC score	0.026988 (rank : 103)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	198	Target Neighborhood Hits	1225	Shared Neighborhood Hits	74
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH6_HUMAN
NC score	0.026978 (rank : 104)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	198	Target Neighborhood Hits	1426	Shared Neighborhood Hits	72
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
NC score	0.026878 (rank : 105)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	198	Target Neighborhood Hits	1501	Shared Neighborhood Hits	75
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH2_HUMAN
NC score	0.026871 (rank : 106)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	198	Target Neighborhood Hits	1491	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

WDR60_MOUSE
NC score	0.026869 (rank : 107)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	198	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

CJ078_MOUSE
NC score	0.026588 (rank : 108)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	198	Target Neighborhood Hits	559	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SETD8_MOUSE
NC score	0.026586 (rank : 109)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	198	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

GOGB1_HUMAN
NC score	0.026528 (rank : 110)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	198	Target Neighborhood Hits	2297	Shared Neighborhood Hits	103
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYRIP_HUMAN
NC score	0.026418 (rank : 111)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	198	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYH8_MOUSE
NC score	0.026248 (rank : 112)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	198	Target Neighborhood Hits	1600	Shared Neighborhood Hits	83
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SYCP1_MOUSE
NC score	0.026180 (rank : 113)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	198	Target Neighborhood Hits	1456	Shared Neighborhood Hits	86
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RIF1_MOUSE
NC score	0.026076 (rank : 114)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	198	Target Neighborhood Hits	315	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

NKTR_HUMAN
NC score	0.026056 (rank : 115)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	198	Target Neighborhood Hits	658	Shared Neighborhood Hits	55
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

MYH13_HUMAN
NC score	0.025945 (rank : 116)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	198	Target Neighborhood Hits	1504	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

CI039_HUMAN
NC score	0.025803 (rank : 117)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	198	Target Neighborhood Hits	1171	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CCD39_MOUSE
NC score	0.025785 (rank : 118)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	198	Target Neighborhood Hits	1026	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

NP1L3_HUMAN
NC score	0.025774 (rank : 119)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	198	Target Neighborhood Hits	172	Shared Neighborhood Hits	35
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

ARI5B_HUMAN
NC score	0.025717 (rank : 120)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	198	Target Neighborhood Hits	328	Shared Neighborhood Hits	26
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

MY18A_HUMAN
NC score	0.025531 (rank : 121)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	198	Target Neighborhood Hits	1929	Shared Neighborhood Hits	89
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
NC score	0.024817 (rank : 122)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	198	Target Neighborhood Hits	1989	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD39_HUMAN
NC score	0.024414 (rank : 123)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	198	Target Neighborhood Hits	868	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

KCNQ2_HUMAN
NC score	0.024297 (rank : 124)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

RRBP1_MOUSE
NC score	0.024253 (rank : 125)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	198	Target Neighborhood Hits	1650	Shared Neighborhood Hits	89
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NEST_HUMAN
NC score	0.023975 (rank : 126)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	198	Target Neighborhood Hits	1305	Shared Neighborhood Hits	81
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

KCNQ4_HUMAN
NC score	0.023745 (rank : 127)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	198	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

CROCC_HUMAN
NC score	0.023581 (rank : 128)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	198	Target Neighborhood Hits	1409	Shared Neighborhood Hits	67
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

KCNQ2_MOUSE
NC score	0.023422 (rank : 129)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	198	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

TR150_MOUSE
NC score	0.022906 (rank : 130)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	198	Target Neighborhood Hits	468	Shared Neighborhood Hits	52
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

NFH_HUMAN
NC score	0.022677 (rank : 131)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	198	Target Neighborhood Hits	1242	Shared Neighborhood Hits	113
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCAL5_HUMAN
NC score	0.022349 (rank : 132)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	198	Target Neighborhood Hits	806	Shared Neighborhood Hits	52
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TE2IP_HUMAN
NC score	0.022142 (rank : 133)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	198	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

CF060_HUMAN
NC score	0.021955 (rank : 134)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	198	Target Neighborhood Hits	1270	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MYRIP_MOUSE
NC score	0.021558 (rank : 135)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	198	Target Neighborhood Hits	207	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NOP14_MOUSE
NC score	0.021538 (rank : 136)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	198	Target Neighborhood Hits	324	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

DMN_HUMAN
NC score	0.021294 (rank : 137)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	198	Target Neighborhood Hits	690	Shared Neighborhood Hits	55
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

ERCC6_HUMAN
NC score	0.021242 (rank : 138)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	198	Target Neighborhood Hits	247	Shared Neighborhood Hits	28
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

MLL3_HUMAN
NC score	0.021094 (rank : 139)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	198	Target Neighborhood Hits	1644	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BPAEA_HUMAN
NC score	0.020983 (rank : 140)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	198	Target Neighborhood Hits	1369	Shared Neighborhood Hits	68
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

FBX41_MOUSE
NC score	0.020924 (rank : 141)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	198	Target Neighborhood Hits	430	Shared Neighborhood Hits	44
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_HUMAN
NC score	0.020917 (rank : 142)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	198	Target Neighborhood Hits	475	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

RFC1_HUMAN
NC score	0.020829 (rank : 143)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	198	Target Neighborhood Hits	352	Shared Neighborhood Hits	38
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

DMD_HUMAN
NC score	0.020263 (rank : 144)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	198	Target Neighborhood Hits	1135	Shared Neighborhood Hits	63
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

TRPM6_MOUSE
NC score	0.020231 (rank : 145)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	198	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

EEA1_MOUSE
NC score	0.020039 (rank : 146)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	198	Target Neighborhood Hits	1637	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

PHF3_HUMAN
NC score	0.020005 (rank : 147)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	198	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RRP5_HUMAN
NC score	0.020001 (rank : 148)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	198	Target Neighborhood Hits	291	Shared Neighborhood Hits	40
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

SAS6_HUMAN
NC score	0.019659 (rank : 149)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	198	Target Neighborhood Hits	791	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

ZCPW1_MOUSE
NC score	0.019643 (rank : 150)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	198	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ASXL1_MOUSE
NC score	0.019536 (rank : 151)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	198	Target Neighborhood Hits	182	Shared Neighborhood Hits	15
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

DMD_MOUSE
NC score	0.019440 (rank : 152)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	198	Target Neighborhood Hits	1111	Shared Neighborhood Hits	61
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

PRGC1_MOUSE
NC score	0.019306 (rank : 153)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	198	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

BCLF1_HUMAN
NC score	0.019046 (rank : 154)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	198	Target Neighborhood Hits	298	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

IP6K2_MOUSE
NC score	0.018929 (rank : 155)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	198	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q80V72	Gene names	Ihpk2, Ip6k2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

CAB45_HUMAN
NC score	0.018782 (rank : 156)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	198	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRK5, Q8NBQ3, Q9NZP7	Gene names	SDF4, CAB45
Domain Architecture
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

NKTR_MOUSE
NC score	0.018617 (rank : 157)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	198	Target Neighborhood Hits	417	Shared Neighborhood Hits	43
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CJ006_HUMAN
NC score	0.018488 (rank : 158)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	198	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

SYNC_MOUSE
NC score	0.018459 (rank : 159)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	198	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

LRMP_HUMAN
NC score	0.018303 (rank : 160)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	198	Target Neighborhood Hits	126	Shared Neighborhood Hits	22
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

XLKD1_HUMAN
NC score	0.018250 (rank : 161)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	198	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

SETD8_HUMAN
NC score	0.018231 (rank : 162)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

TNNT2_MOUSE
NC score	0.018078 (rank : 163)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	198	Target Neighborhood Hits	395	Shared Neighborhood Hits	45
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

ZN292_HUMAN
NC score	0.018000 (rank : 164)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	198	Target Neighborhood Hits	918	Shared Neighborhood Hits	42
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

K0552_HUMAN
NC score	0.017486 (rank : 165)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	198	Target Neighborhood Hits	442	Shared Neighborhood Hits	41
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

ASXL1_HUMAN
NC score	0.017414 (rank : 166)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	198	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PEPL_MOUSE
NC score	0.017338 (rank : 167)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	198	Target Neighborhood Hits	1105	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

JHD1B_HUMAN
NC score	0.017137 (rank : 168)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	198	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

ITPR3_HUMAN
NC score	0.016479 (rank : 169)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	198	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

WDR47_HUMAN
NC score	0.016144 (rank : 170)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	198	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

OTU6B_MOUSE
NC score	0.015995 (rank : 171)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	198	Target Neighborhood Hits	202	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

DNJC8_MOUSE
NC score	0.015871 (rank : 172)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	198	Target Neighborhood Hits	392	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

GASP1_MOUSE
NC score	0.015712 (rank : 173)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	198	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

DNJC8_HUMAN
NC score	0.015664 (rank : 174)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	198	Target Neighborhood Hits	380	Shared Neighborhood Hits	33
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

MRCKB_HUMAN
NC score	0.015605 (rank : 175)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	198	Target Neighborhood Hits	2239	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ICAL_HUMAN
NC score	0.015559 (rank : 176)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	198	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

AHTF1_HUMAN
NC score	0.015512 (rank : 177)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	198	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

MRCKB_MOUSE
NC score	0.015432 (rank : 178)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	198	Target Neighborhood Hits	2180	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

JHD1B_MOUSE
NC score	0.014982 (rank : 179)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	198	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

STK10_MOUSE
NC score	0.014468 (rank : 180)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	198	Target Neighborhood Hits	2132	Shared Neighborhood Hits	93
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

KCNQ5_HUMAN
NC score	0.014364 (rank : 181)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	198	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

CAB45_MOUSE
NC score	0.013848 (rank : 182)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	198	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q61112, Q61113	Gene names	Sdf4, Cab45
Domain Architecture	No domain graphic available
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

ANR18_HUMAN
NC score	0.013772 (rank : 183)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	198	Target Neighborhood Hits	1106	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

PACN2_MOUSE
NC score	0.013755 (rank : 184)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	198	Target Neighborhood Hits	382	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

MEPE_HUMAN
NC score	0.013532 (rank : 185)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	198	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

MCPH1_HUMAN
NC score	0.013531 (rank : 186)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	198	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

MBB1A_MOUSE
NC score	0.013090 (rank : 187)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	198	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

TAF4_HUMAN
NC score	0.012891 (rank : 188)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	198	Target Neighborhood Hits	687	Shared Neighborhood Hits	31
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ITSN1_HUMAN
NC score	0.012848 (rank : 189)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	198	Target Neighborhood Hits	1757	Shared Neighborhood Hits	81
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PSMD2_MOUSE
NC score	0.012462 (rank : 190)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	198	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

AKAP2_HUMAN
NC score	0.012319 (rank : 191)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	198	Target Neighborhood Hits	507	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

INP4B_HUMAN
NC score	0.012112 (rank : 192)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	198	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	O15327, Q6IN59, Q6PJB4	Gene names	INPP4B
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

SLK_MOUSE
NC score	0.011937 (rank : 193)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	198	Target Neighborhood Hits	1798	Shared Neighborhood Hits	78
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SEC63_MOUSE
NC score	0.011913 (rank : 194)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	198	Target Neighborhood Hits	601	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SLK_HUMAN
NC score	0.011884 (rank : 195)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	198	Target Neighborhood Hits	1775	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

MO4L2_HUMAN
NC score	0.010943 (rank : 196)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	198	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

TEX14_HUMAN
NC score	0.010574 (rank : 197)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	198	Target Neighborhood Hits	1103	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TTF2_MOUSE
NC score	0.010214 (rank : 198)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	198	Target Neighborhood Hits	364	Shared Neighborhood Hits	24
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

PARP1_MOUSE
NC score	0.010194 (rank : 199)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	198	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

IF4E3_HUMAN
NC score	0.007714 (rank : 200)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	198	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O60573, O75349	Gene names	EIF4EL3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (Eukaryotic translation initiation factor 4E homologous protein) (mRNA cap-binding protein 4EHP) (eIF4E-like protein 4E-LP).

PACN2_HUMAN
NC score	0.007283 (rank : 201)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	198	Target Neighborhood Hits	339	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

TRI63_HUMAN
NC score	0.006553 (rank : 202)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	198	Target Neighborhood Hits	298	Shared Neighborhood Hits	22
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

ADA30_HUMAN
NC score	0.004919 (rank : 203)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	198	Target Neighborhood Hits	391	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

TSH1_MOUSE
NC score	0.004214 (rank : 204)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	198	Target Neighborhood Hits	675	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

SHOC2_HUMAN
NC score	0.003420 (rank : 205)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	198	Target Neighborhood Hits	330	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ13, O76063	Gene names	SHOC2, KIAA0862
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

DOCK8_MOUSE
NC score	0.003030 (rank : 206)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	198	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

SMP1L_MOUSE
NC score	0.002422 (rank : 207)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	198	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

FOXN3_HUMAN
NC score	0.001664 (rank : 208)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	198	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

ZFP37_MOUSE
NC score	-0.003628 (rank : 209)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	198	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZKSC1_HUMAN
NC score	-0.003981 (rank : 210)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	198	Target Neighborhood Hits	949	Shared Neighborhood Hits	24
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).