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Network neighborhood for query Sequence : IF4E3_HUMAN

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IF4E3_HUMAN
SwissProt Accessions	O60573, O75349	Gene names	EIF4EL3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (Eukaryotic translation initiation factor 4E homologous protein) (mRNA cap-binding protein 4EHP) (eIF4E-like protein 4E-LP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IF4E3_HUMAN
θ value	2.68277e-145 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O60573, O75349	Gene names	EIF4EL3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (Eukaryotic translation initiation factor 4E homologous protein) (mRNA cap-binding protein 4EHP) (eIF4E-like protein 4E-LP).

IF4E3_MOUSE
θ value	1.47209e-143 (rank : 2)	NC score	0.997631 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMB3, O88503, Q3UCK2	Gene names	Eif4el3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP).

IF4E_HUMAN
θ value	6.38894e-30 (rank : 3)	NC score	0.838284 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P06730, Q96E95	Gene names	EIF4E
Domain Architecture
Description	Eukaryotic translation initiation factor 4E (eIF4E) (eIF-4E) (mRNA cap-binding protein) (eIF-4F 25 kDa subunit).

IF4E_MOUSE
θ value	8.3442e-30 (rank : 4)	NC score	0.837941 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P63073, P20415	Gene names	Eif4e
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E (eIF4E) (eIF-4E) (mRNA cap-binding protein) (eIF-4F 25 kDa subunit).

AP3D1_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.051588 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

ATAD2_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.024170 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	322	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

TULP1_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.039361 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

PTPRG_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.017786 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

FA40A_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.041518 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C079, Q80T92, Q8BZC6, Q8CIF7	Gene names	Fam40a, Kiaa1761
Domain Architecture	No domain graphic available
Description	Protein FAM40A.

PTPRG_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.017457 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

FA40A_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.039496 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VSL9, Q5VSL8, Q658K2, Q6ZV31, Q8N598, Q96SN2, Q9C0A2	Gene names	FAM40A, KIAA1761
Domain Architecture	No domain graphic available
Description	Protein FAM40A.

CF010_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.035081 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CYLC2_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.039639 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	223	Shared Neighborhood Hits	4
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

IF2P_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.013834 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NCOR1_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.020153 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	577	Shared Neighborhood Hits	6
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ABCF1_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.016578 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

CNGA1_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.007714 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	198	Shared Neighborhood Hits	2
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CT112_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.023803 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

CT112_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.023408 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

SMCA2_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.010997 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	503	Shared Neighborhood Hits	4
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

UBF1_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.012072 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	415	Shared Neighborhood Hits	3
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

PTMS_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.026102 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

Hits sorted by NC score

IF4E3_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.68277e-145 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O60573, O75349	Gene names	EIF4EL3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (Eukaryotic translation initiation factor 4E homologous protein) (mRNA cap-binding protein 4EHP) (eIF4E-like protein 4E-LP).

IF4E3_MOUSE
NC score	0.997631 (rank : 2)	θ value	1.47209e-143 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMB3, O88503, Q3UCK2	Gene names	Eif4el3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP).

IF4E_HUMAN
NC score	0.838284 (rank : 3)	θ value	6.38894e-30 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P06730, Q96E95	Gene names	EIF4E
Domain Architecture
Description	Eukaryotic translation initiation factor 4E (eIF4E) (eIF-4E) (mRNA cap-binding protein) (eIF-4F 25 kDa subunit).

IF4E_MOUSE
NC score	0.837941 (rank : 4)	θ value	8.3442e-30 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P63073, P20415	Gene names	Eif4e
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E (eIF4E) (eIF-4E) (mRNA cap-binding protein) (eIF-4F 25 kDa subunit).

AP3D1_MOUSE
NC score	0.051588 (rank : 5)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

FA40A_MOUSE
NC score	0.041518 (rank : 6)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C079, Q80T92, Q8BZC6, Q8CIF7	Gene names	Fam40a, Kiaa1761
Domain Architecture	No domain graphic available
Description	Protein FAM40A.

CYLC2_HUMAN
NC score	0.039639 (rank : 7)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	223	Shared Neighborhood Hits	4
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

FA40A_HUMAN
NC score	0.039496 (rank : 8)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VSL9, Q5VSL8, Q658K2, Q6ZV31, Q8N598, Q96SN2, Q9C0A2	Gene names	FAM40A, KIAA1761
Domain Architecture	No domain graphic available
Description	Protein FAM40A.

TULP1_MOUSE
NC score	0.039361 (rank : 9)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

CF010_HUMAN
NC score	0.035081 (rank : 10)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

PTMS_MOUSE
NC score	0.026102 (rank : 11)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

ATAD2_HUMAN
NC score	0.024170 (rank : 12)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	322	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

CT112_HUMAN
NC score	0.023803 (rank : 13)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

CT112_MOUSE
NC score	0.023408 (rank : 14)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

NCOR1_HUMAN
NC score	0.020153 (rank : 15)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	577	Shared Neighborhood Hits	6
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

PTPRG_MOUSE
NC score	0.017786 (rank : 16)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.017457 (rank : 17)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

ABCF1_MOUSE
NC score	0.016578 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

IF2P_HUMAN
NC score	0.013834 (rank : 19)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

UBF1_HUMAN
NC score	0.012072 (rank : 20)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	415	Shared Neighborhood Hits	3
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

SMCA2_HUMAN
NC score	0.010997 (rank : 21)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	503	Shared Neighborhood Hits	4
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

CNGA1_MOUSE
NC score	0.007714 (rank : 22)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	198	Shared Neighborhood Hits	2
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).