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Network neighborhood for query Sequence : KCNK2_MOUSE

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KCNK2_MOUSE
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNK2_HUMAN
θ value	0 (rank : 1)	NC score	0.999523 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	83
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNKA_HUMAN
θ value	7.09276e-130 (rank : 3)	NC score	0.986254 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK4_HUMAN
θ value	5.15425e-80 (rank : 4)	NC score	0.965325 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK4_MOUSE
θ value	3.12697e-77 (rank : 5)	NC score	0.963420 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	63
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNKG_HUMAN
θ value	4.40402e-47 (rank : 6)	NC score	0.958155 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	81
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK5_HUMAN
θ value	4.41421e-39 (rank : 7)	NC score	0.929458 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	79
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNKH_HUMAN
θ value	3.86705e-35 (rank : 8)	NC score	0.932564 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	81
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK1_HUMAN
θ value	1.16434e-31 (rank : 9)	NC score	0.891152 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	68	Shared Neighborhood Hits	59
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK3_HUMAN
θ value	5.77852e-31 (rank : 10)	NC score	0.868428 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	79
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK1_MOUSE
θ value	9.8567e-31 (rank : 11)	NC score	0.888942 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK6_HUMAN
θ value	3.74554e-30 (rank : 12)	NC score	0.911483 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKF_HUMAN
θ value	3.74554e-30 (rank : 13)	NC score	0.877907 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK9_MOUSE
θ value	5.40856e-29 (rank : 14)	NC score	0.868647 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK3_MOUSE
θ value	2.68423e-28 (rank : 15)	NC score	0.865480 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK9_HUMAN
θ value	2.96777e-27 (rank : 16)	NC score	0.861819 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK7_MOUSE
θ value	9.54697e-26 (rank : 17)	NC score	0.866535 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK7_HUMAN
θ value	4.01107e-24 (rank : 18)	NC score	0.855888 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNKC_HUMAN
θ value	8.36355e-22 (rank : 19)	NC score	0.814572 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_MOUSE
θ value	7.82807e-20 (rank : 20)	NC score	0.800881 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_HUMAN
θ value	6.62687e-19 (rank : 21)	NC score	0.793966 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNH5_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.224145 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	0.000602161 (rank : 23)	NC score	0.224215 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_HUMAN
θ value	0.00298849 (rank : 24)	NC score	0.216201 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	0.00298849 (rank : 25)	NC score	0.216379 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH8_HUMAN
θ value	0.00869519 (rank : 26)	NC score	0.187561 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH2_HUMAN
θ value	0.0113563 (rank : 27)	NC score	0.183439 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	158	Shared Neighborhood Hits	46
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	0.0113563 (rank : 28)	NC score	0.183304 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_HUMAN
θ value	0.0113563 (rank : 29)	NC score	0.190278 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH7_MOUSE
θ value	0.0113563 (rank : 30)	NC score	0.188524 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
θ value	0.0148317 (rank : 31)	NC score	0.189702 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	222	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH3_HUMAN
θ value	0.0563607 (rank : 32)	NC score	0.181386 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	0.0563607 (rank : 33)	NC score	0.182717 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNA5_HUMAN
θ value	0.0736092 (rank : 34)	NC score	0.162589 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	68
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA4_HUMAN
θ value	0.0961366 (rank : 35)	NC score	0.168984 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCND3_HUMAN
θ value	0.125558 (rank : 36)	NC score	0.175641 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.175732 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNA5_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.159348 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCND1_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.178406 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	160	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNC4_HUMAN
θ value	0.21417 (rank : 40)	NC score	0.145143 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	141	Shared Neighborhood Hits	60
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.145593 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCND2_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.176019 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.279714 (rank : 43)	NC score	0.175995 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	156	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNA4_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.157691 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	65
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA6_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.160671 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.158774 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	65
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC1_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.143769 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	0.365318 (rank : 48)	NC score	0.143793 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNQ4_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.168117 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	136	Shared Neighborhood Hits	68
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNA3_HUMAN
θ value	0.62314 (rank : 50)	NC score	0.153993 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	0.62314 (rank : 51)	NC score	0.155814 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNC3_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.141465 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	256	Shared Neighborhood Hits	61
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCND1_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.174561 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	82
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNA2_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.153403 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	68
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.153536 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNH4_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.171288 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNN4_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.126627 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	70
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNQ2_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.148442 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	0.813845 (rank : 59)	NC score	0.147612 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	163	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNA1_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.147550 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	63
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.147547 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNB1_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.134112 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	169	Shared Neighborhood Hits	67
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.134144 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	67
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB2_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.133867 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNF1_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.145486 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNN4_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.126869 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNV2_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.143674 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	137	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNC3_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.135021 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	173	Shared Neighborhood Hits	59
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG2_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.127931 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	83	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNQ5_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.148931 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	163	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCMA1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.162670 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.162991 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNG1_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.128160 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNQ1_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.146804 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ3_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.140519 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.140161 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNT1_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.167063 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNQ1_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.144729 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	175	Shared Neighborhood Hits	62
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNS1_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.130534 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	65
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNT1_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.149074 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCNN1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.082776 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

CENPF_HUMAN
θ value	6.88961 (rank : 82)	NC score	-0.003631 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	1932	Shared Neighborhood Hits	3
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KCNG4_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.117779 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNN1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.079493 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	63
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

FBX22_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.012967 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q78JE5	Gene names	Fbxo22, Fbx22
Domain Architecture	No domain graphic available
Description	F-box only protein 22.

RB6I2_MOUSE
θ value	8.99809 (rank : 86)	NC score	-0.003296 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	1433	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SPRE3_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.005079 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

TMM20_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.025340 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q2M3R5, Q86YG5, Q8NBA5	Gene names	TMEM20, C10orf60
Domain Architecture	No domain graphic available
Description	Transmembrane protein 20.

CNGA1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.065719 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	149	Shared Neighborhood Hits	16
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.064986 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.067694 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.065396 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.067030 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.052296 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.055101 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.056519 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

HCN1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.063039 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.062568 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.060218 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	369	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.060780 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.061378 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.061341 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.061902 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.060834 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	284	Shared Neighborhood Hits	14
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

KCNG3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.112782 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.112891 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	54
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNN2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.076225 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.076229 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.073261 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.073286 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	171	Shared Neighborhood Hits	63
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCNS1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.119457 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	116	Shared Neighborhood Hits	57
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS2_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.131464 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.131380 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	66
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS3_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.111652 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

Hits sorted by NC score

KCNK2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK2_HUMAN
NC score	0.999523 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	83
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNKA_HUMAN
NC score	0.986254 (rank : 3)	θ value	7.09276e-130 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK4_HUMAN
NC score	0.965325 (rank : 4)	θ value	5.15425e-80 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK4_MOUSE
NC score	0.963420 (rank : 5)	θ value	3.12697e-77 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	63
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNKG_HUMAN
NC score	0.958155 (rank : 6)	θ value	4.40402e-47 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	81
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
NC score	0.932564 (rank : 7)	θ value	3.86705e-35 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	81
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK5_HUMAN
NC score	0.929458 (rank : 8)	θ value	4.41421e-39 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	79
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK6_HUMAN
NC score	0.911483 (rank : 9)	θ value	3.74554e-30 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK1_HUMAN
NC score	0.891152 (rank : 10)	θ value	1.16434e-31 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	68	Shared Neighborhood Hits	59
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
NC score	0.888942 (rank : 11)	θ value	9.8567e-31 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNKF_HUMAN
NC score	0.877907 (rank : 12)	θ value	3.74554e-30 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK9_MOUSE
NC score	0.868647 (rank : 13)	θ value	5.40856e-29 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK3_HUMAN
NC score	0.868428 (rank : 14)	θ value	5.77852e-31 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	79
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK7_MOUSE
NC score	0.866535 (rank : 15)	θ value	9.54697e-26 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK3_MOUSE
NC score	0.865480 (rank : 16)	θ value	2.68423e-28 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK9_HUMAN
NC score	0.861819 (rank : 17)	θ value	2.96777e-27 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK7_HUMAN
NC score	0.855888 (rank : 18)	θ value	4.01107e-24 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNKC_HUMAN
NC score	0.814572 (rank : 19)	θ value	8.36355e-22 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_MOUSE
NC score	0.800881 (rank : 20)	θ value	7.82807e-20 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_HUMAN
NC score	0.793966 (rank : 21)	θ value	6.62687e-19 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNH5_MOUSE
NC score	0.224215 (rank : 22)	θ value	0.000602161 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.224145 (rank : 23)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH1_MOUSE
NC score	0.216379 (rank : 24)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.216201 (rank : 25)	θ value	0.00298849 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH7_HUMAN
NC score	0.190278 (rank : 26)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH6_HUMAN
NC score	0.189702 (rank : 27)	θ value	0.0148317 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	222	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH7_MOUSE
NC score	0.188524 (rank : 28)	θ value	0.0113563 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH8_HUMAN
NC score	0.187561 (rank : 29)	θ value	0.00869519 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH2_HUMAN
NC score	0.183439 (rank : 30)	θ value	0.0113563 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	158	Shared Neighborhood Hits	46
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.183304 (rank : 31)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH3_MOUSE
NC score	0.182717 (rank : 32)	θ value	0.0563607 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.181386 (rank : 33)	θ value	0.0563607 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCND1_HUMAN
NC score	0.178406 (rank : 34)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	160	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_HUMAN
NC score	0.176019 (rank : 35)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
NC score	0.175995 (rank : 36)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	156	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_MOUSE
NC score	0.175732 (rank : 37)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.175641 (rank : 38)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND1_MOUSE
NC score	0.174561 (rank : 39)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	82
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNH4_HUMAN
NC score	0.171288 (rank : 40)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNA4_HUMAN
NC score	0.168984 (rank : 41)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ4_HUMAN
NC score	0.168117 (rank : 42)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	136	Shared Neighborhood Hits	68
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNT1_HUMAN
NC score	0.167063 (rank : 43)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCMA1_MOUSE
NC score	0.162991 (rank : 44)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.162670 (rank : 45)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNA5_HUMAN
NC score	0.162589 (rank : 46)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	68
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA6_HUMAN
NC score	0.160671 (rank : 47)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_MOUSE
NC score	0.159348 (rank : 48)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_MOUSE
NC score	0.158774 (rank : 49)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	65
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA4_MOUSE
NC score	0.157691 (rank : 50)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	65
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA3_MOUSE
NC score	0.155814 (rank : 51)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA3_HUMAN
NC score	0.153993 (rank : 52)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA2_MOUSE
NC score	0.153536 (rank : 53)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.153403 (rank : 54)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	68
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNT1_MOUSE
NC score	0.149074 (rank : 55)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCNQ5_HUMAN
NC score	0.148931 (rank : 56)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	163	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ2_HUMAN
NC score	0.148442 (rank : 57)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.147612 (rank : 58)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	163	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNA1_HUMAN
NC score	0.147550 (rank : 59)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	63
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
NC score	0.147547 (rank : 60)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNQ1_HUMAN
NC score	0.146804 (rank : 61)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNC4_MOUSE
NC score	0.145593 (rank : 62)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNF1_HUMAN
NC score	0.145486 (rank : 63)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNC4_HUMAN
NC score	0.145143 (rank : 64)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	141	Shared Neighborhood Hits	60
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNQ1_MOUSE
NC score	0.144729 (rank : 65)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	175	Shared Neighborhood Hits	62
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNC1_MOUSE
NC score	0.143793 (rank : 66)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
NC score	0.143769 (rank : 67)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNV2_HUMAN
NC score	0.143674 (rank : 68)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	137	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNC3_HUMAN
NC score	0.141465 (rank : 69)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	256	Shared Neighborhood Hits	61
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNQ3_HUMAN
NC score	0.140519 (rank : 70)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.140161 (rank : 71)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNC3_MOUSE
NC score	0.135021 (rank : 72)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	173	Shared Neighborhood Hits	59
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNB1_MOUSE
NC score	0.134144 (rank : 73)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	67
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.134112 (rank : 74)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	169	Shared Neighborhood Hits	67
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB2_HUMAN
NC score	0.133867 (rank : 75)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_HUMAN
NC score	0.131464 (rank : 76)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
NC score	0.131380 (rank : 77)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	66
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS1_MOUSE
NC score	0.130534 (rank : 78)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	65
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG1_HUMAN
NC score	0.128160 (rank : 79)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
NC score	0.127931 (rank : 80)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	83	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNN4_MOUSE
NC score	0.126869 (rank : 81)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNN4_HUMAN
NC score	0.126627 (rank : 82)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	70
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNS1_HUMAN
NC score	0.119457 (rank : 83)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	116	Shared Neighborhood Hits	57
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG4_HUMAN
NC score	0.117779 (rank : 84)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNG3_MOUSE
NC score	0.112891 (rank : 85)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	54
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
NC score	0.112782 (rank : 86)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNS3_HUMAN
NC score	0.111652 (rank : 87)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNN1_MOUSE
NC score	0.082776 (rank : 88)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_HUMAN
NC score	0.079493 (rank : 89)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	63
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN2_MOUSE
NC score	0.076229 (rank : 90)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_HUMAN
NC score	0.076225 (rank : 91)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_MOUSE
NC score	0.073286 (rank : 92)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	171	Shared Neighborhood Hits	63
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCNN3_HUMAN
NC score	0.073261 (rank : 93)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

CNGA2_MOUSE
NC score	0.067694 (rank : 94)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.067030 (rank : 95)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.065719 (rank : 96)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	149	Shared Neighborhood Hits	16
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.065396 (rank : 97)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.064986 (rank : 98)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.063039 (rank : 99)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.062568 (rank : 100)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN4_HUMAN
NC score	0.061902 (rank : 101)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN3_HUMAN
NC score	0.061378 (rank : 102)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
NC score	0.061341 (rank : 103)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_MOUSE
NC score	0.060834 (rank : 104)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	284	Shared Neighborhood Hits	14
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_MOUSE
NC score	0.060780 (rank : 105)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN2_HUMAN
NC score	0.060218 (rank : 106)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	369	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.056519 (rank : 107)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.055101 (rank : 108)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.052296 (rank : 109)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

TMM20_HUMAN
NC score	0.025340 (rank : 110)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q2M3R5, Q86YG5, Q8NBA5	Gene names	TMEM20, C10orf60
Domain Architecture	No domain graphic available
Description	Transmembrane protein 20.

FBX22_MOUSE
NC score	0.012967 (rank : 111)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q78JE5	Gene names	Fbxo22, Fbx22
Domain Architecture	No domain graphic available
Description	F-box only protein 22.

SPRE3_MOUSE
NC score	0.005079 (rank : 112)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

RB6I2_MOUSE
NC score	-0.003296 (rank : 113)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	1433	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CENPF_HUMAN
NC score	-0.003631 (rank : 114)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	1932	Shared Neighborhood Hits	3
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).