Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CNGA3_MOUSE

For an explanation of this page, click here

CNGA3_MOUSE
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CNGA1_HUMAN
θ value	0 (rank : 1)	NC score	0.989347 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	0 (rank : 2)	NC score	0.985341 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	198	Shared Neighborhood Hits	51
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	0 (rank : 3)	NC score	0.993471 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_HUMAN
θ value	0 (rank : 4)	NC score	0.995200 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB1_HUMAN
θ value	2.73302e-81 (rank : 6)	NC score	0.930734 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	222	Shared Neighborhood Hits	48
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
θ value	6.73165e-80 (rank : 7)	NC score	0.933445 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	206	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	6.10265e-73 (rank : 8)	NC score	0.945191 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

HCN4_HUMAN
θ value	2.26182e-43 (rank : 9)	NC score	0.841148 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN1_HUMAN
θ value	8.59492e-43 (rank : 10)	NC score	0.861301 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	8.59492e-43 (rank : 11)	NC score	0.857414 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	172	Shared Neighborhood Hits	45
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_MOUSE
θ value	1.2411e-41 (rank : 12)	NC score	0.844106 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_MOUSE
θ value	6.15952e-41 (rank : 13)	NC score	0.839393 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN3_MOUSE
θ value	1.05066e-40 (rank : 14)	NC score	0.858101 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN2_HUMAN
θ value	1.3722e-40 (rank : 15)	NC score	0.833750 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	369	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN3_HUMAN
θ value	3.05695e-40 (rank : 16)	NC score	0.857233 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

KCNH2_HUMAN
θ value	1.12514e-34 (rank : 17)	NC score	0.811748 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	1.12514e-34 (rank : 18)	NC score	0.811639 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
θ value	9.52487e-34 (rank : 19)	NC score	0.812551 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
θ value	1.37539e-32 (rank : 20)	NC score	0.811845 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH3_MOUSE
θ value	6.82597e-32 (rank : 21)	NC score	0.797120 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH8_HUMAN
θ value	8.91499e-32 (rank : 22)	NC score	0.806520 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	104	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH7_HUMAN
θ value	1.52067e-31 (rank : 23)	NC score	0.807371 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	107	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH3_HUMAN
θ value	4.42448e-31 (rank : 24)	NC score	0.797070 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	148	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH4_HUMAN
θ value	5.77852e-31 (rank : 25)	NC score	0.807657 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	177	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_HUMAN
θ value	2.42779e-29 (rank : 26)	NC score	0.798088 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	2.42779e-29 (rank : 27)	NC score	0.798379 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_MOUSE
θ value	7.80994e-28 (rank : 28)	NC score	0.794466 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
θ value	1.33217e-27 (rank : 29)	NC score	0.794199 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KGP1B_MOUSE
θ value	0.000602161 (rank : 30)	NC score	0.071412 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	922	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
θ value	0.000786445 (rank : 31)	NC score	0.070847 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	901	Shared Neighborhood Hits	44
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.000786445 (rank : 32)	NC score	0.071159 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	921	Shared Neighborhood Hits	46
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP2_HUMAN
θ value	0.00175202 (rank : 33)	NC score	0.068847 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	1023	Shared Neighborhood Hits	44
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
θ value	0.00175202 (rank : 34)	NC score	0.068539 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	1029	Shared Neighborhood Hits	43
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KAP1_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.239123 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.0113563 (rank : 36)	NC score	0.233692 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP0_HUMAN
θ value	0.0252991 (rank : 37)	NC score	0.254763 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP3_MOUSE
θ value	0.0252991 (rank : 38)	NC score	0.200899 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP0_MOUSE
θ value	0.0330416 (rank : 39)	NC score	0.237347 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP3_HUMAN
θ value	0.0563607 (rank : 40)	NC score	0.194870 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

SMC4_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.041110 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	937	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	0.0961366 (rank : 42)	NC score	0.048117 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	830	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

FYCO1_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.015051 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	1059	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

HMMR_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.019171 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	1178	Shared Neighborhood Hits	27
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SYYC_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.022945 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

MAP1A_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.031788 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	1626	Shared Neighborhood Hits	32
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CT152_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.118003 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

CT152_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.153142 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNK5_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.045942 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KNTC2_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.012996 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	692	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

LMNB1_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.008271 (rank : 88)
Query Neighborhood Hits	84	Target Neighborhood Hits	719	Shared Neighborhood Hits	27
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

PK3CB_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.009479 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

GOGB1_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.012728 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	2297	Shared Neighborhood Hits	36
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HOOK2_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.013205 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	714	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

K2C4_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.005472 (rank : 95)
Query Neighborhood Hits	84	Target Neighborhood Hits	521	Shared Neighborhood Hits	24
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

MYH9_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.009318 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.009931 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	1829	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CENPE_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.008002 (rank : 90)
Query Neighborhood Hits	84	Target Neighborhood Hits	2060	Shared Neighborhood Hits	34
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RENT2_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.014845 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	618	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RPGF3_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.061672 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

CECR2_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.015262 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	543	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

GOGA3_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.009967 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	1437	Shared Neighborhood Hits	31
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

JIP4_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.018446 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	585	Shared Neighborhood Hits	21
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

RPGF3_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.055140 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

BPA1_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.005586 (rank : 94)
Query Neighborhood Hits	84	Target Neighborhood Hits	1477	Shared Neighborhood Hits	26
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HOOK2_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.010399 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	736	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

KCNQ3_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.033575 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.034100 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KIF5A_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.004992 (rank : 96)
Query Neighborhood Hits	84	Target Neighborhood Hits	859	Shared Neighborhood Hits	24
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LMNB1_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.007418 (rank : 92)
Query Neighborhood Hits	84	Target Neighborhood Hits	714	Shared Neighborhood Hits	27
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

MYH7_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.008137 (rank : 89)
Query Neighborhood Hits	84	Target Neighborhood Hits	1559	Shared Neighborhood Hits	33
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

BCL7A_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.007805 (rank : 91)
Query Neighborhood Hits	84	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CTTB2_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.002097 (rank : 98)
Query Neighborhood Hits	84	Target Neighborhood Hits	1061	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

HOOK1_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.013018 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	942	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

KCMA1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.037723 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.037789 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

SYYC_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.016697 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P54577, O43276, Q53EN1	Gene names	YARS
Domain Architecture
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

5HT7R_HUMAN
θ value	8.99809 (rank : 78)	NC score	-0.003812 (rank : 99)
Query Neighborhood Hits	84	Target Neighborhood Hits	848	Shared Neighborhood Hits	2
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

BCN1_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.008902 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	395	Shared Neighborhood Hits	20
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

GOGA3_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.012044 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	1317	Shared Neighborhood Hits	31
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

JIP4_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.016363 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	593	Shared Neighborhood Hits	22
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

PCLO_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.006345 (rank : 93)
Query Neighborhood Hits	84	Target Neighborhood Hits	2046	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHF10_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.002995 (rank : 97)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

SURF5_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.008988 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q15528, O76072	Gene names	SURF5, SURF-5
Domain Architecture
Description	Surfeit locus protein 5.

KAP2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.182508 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.185792 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KCNK2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.067500 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.067030 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.064700 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.062845 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.058258 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK4_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.050891 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK6_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.065402 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.062818 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.069247 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.056043 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.104139 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

RPGF4_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.062105 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.065060 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

Hits sorted by NC score

CNGA3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.995200 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
NC score	0.993471 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.989347 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.985341 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	198	Shared Neighborhood Hits	51
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
NC score	0.945191 (rank : 6)	θ value	6.10265e-73 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.933445 (rank : 7)	θ value	6.73165e-80 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	206	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.930734 (rank : 8)	θ value	2.73302e-81 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	222	Shared Neighborhood Hits	48
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

HCN1_HUMAN
NC score	0.861301 (rank : 9)	θ value	8.59492e-43 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN3_MOUSE
NC score	0.858101 (rank : 10)	θ value	1.05066e-40 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN1_MOUSE
NC score	0.857414 (rank : 11)	θ value	8.59492e-43 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	172	Shared Neighborhood Hits	45
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_HUMAN
NC score	0.857233 (rank : 12)	θ value	3.05695e-40 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.844106 (rank : 13)	θ value	1.2411e-41 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.841148 (rank : 14)	θ value	2.26182e-43 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.839393 (rank : 15)	θ value	6.15952e-41 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.833750 (rank : 16)	θ value	1.3722e-40 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	369	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCNH7_MOUSE
NC score	0.812551 (rank : 17)	θ value	9.52487e-34 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
NC score	0.811845 (rank : 18)	θ value	1.37539e-32 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.811748 (rank : 19)	θ value	1.12514e-34 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.811639 (rank : 20)	θ value	1.12514e-34 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH4_HUMAN
NC score	0.807657 (rank : 21)	θ value	5.77852e-31 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	177	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH7_HUMAN
NC score	0.807371 (rank : 22)	θ value	1.52067e-31 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	107	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH8_HUMAN
NC score	0.806520 (rank : 23)	θ value	8.91499e-32 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	104	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH5_MOUSE
NC score	0.798379 (rank : 24)	θ value	2.42779e-29 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.798088 (rank : 25)	θ value	2.42779e-29 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH3_MOUSE
NC score	0.797120 (rank : 26)	θ value	6.82597e-32 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.797070 (rank : 27)	θ value	4.42448e-31 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	148	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH1_MOUSE
NC score	0.794466 (rank : 28)	θ value	7.80994e-28 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.794199 (rank : 29)	θ value	1.33217e-27 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KAP0_HUMAN
NC score	0.254763 (rank : 30)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP1_HUMAN
NC score	0.239123 (rank : 31)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP0_MOUSE
NC score	0.237347 (rank : 32)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_MOUSE
NC score	0.233692 (rank : 33)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP3_MOUSE
NC score	0.200899 (rank : 34)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.194870 (rank : 35)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.185792 (rank : 36)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.182508 (rank : 37)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

CT152_MOUSE
NC score	0.153142 (rank : 38)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

CT152_HUMAN
NC score	0.118003 (rank : 39)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNKH_HUMAN
NC score	0.104139 (rank : 40)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	84	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KGP1B_MOUSE
NC score	0.071412 (rank : 41)	θ value	0.000602161 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	922	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.071159 (rank : 42)	θ value	0.000786445 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	921	Shared Neighborhood Hits	46
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.070847 (rank : 43)	θ value	0.000786445 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	901	Shared Neighborhood Hits	44
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KCNKF_HUMAN
NC score	0.069247 (rank : 44)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KGP2_HUMAN
NC score	0.068847 (rank : 45)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	1023	Shared Neighborhood Hits	44
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
NC score	0.068539 (rank : 46)	θ value	0.00175202 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	1029	Shared Neighborhood Hits	43
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNK2_HUMAN
NC score	0.067500 (rank : 47)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.067030 (rank : 48)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.065402 (rank : 49)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	84	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

RPGF4_MOUSE
NC score	0.065060 (rank : 50)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	84	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

KCNK3_HUMAN
NC score	0.064700 (rank : 51)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.062845 (rank : 52)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	84	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.062818 (rank : 53)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

RPGF4_HUMAN
NC score	0.062105 (rank : 54)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF3_MOUSE
NC score	0.061672 (rank : 55)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

KCNK4_HUMAN
NC score	0.058258 (rank : 56)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	84	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.056043 (rank : 57)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	84	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

RPGF3_HUMAN
NC score	0.055140 (rank : 58)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

KCNK4_MOUSE
NC score	0.050891 (rank : 59)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	84	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

SMC4_MOUSE
NC score	0.048117 (rank : 60)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	830	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

KCNK5_HUMAN
NC score	0.045942 (rank : 61)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

SMC4_HUMAN
NC score	0.041110 (rank : 62)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	937	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

KCMA1_MOUSE
NC score	0.037789 (rank : 63)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.037723 (rank : 64)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNQ3_MOUSE
NC score	0.034100 (rank : 65)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.033575 (rank : 66)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MAP1A_HUMAN
NC score	0.031788 (rank : 67)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	1626	Shared Neighborhood Hits	32
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SYYC_MOUSE
NC score	0.022945 (rank : 68)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

HMMR_MOUSE
NC score	0.019171 (rank : 69)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	1178	Shared Neighborhood Hits	27
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

JIP4_HUMAN
NC score	0.018446 (rank : 70)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	585	Shared Neighborhood Hits	21
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

SYYC_HUMAN
NC score	0.016697 (rank : 71)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P54577, O43276, Q53EN1	Gene names	YARS
Domain Architecture
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

JIP4_MOUSE
NC score	0.016363 (rank : 72)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	593	Shared Neighborhood Hits	22
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

CECR2_HUMAN
NC score	0.015262 (rank : 73)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	543	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

FYCO1_MOUSE
NC score	0.015051 (rank : 74)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	1059	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

RENT2_HUMAN
NC score	0.014845 (rank : 75)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	618	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

HOOK2_HUMAN
NC score	0.013205 (rank : 76)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	714	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK1_HUMAN
NC score	0.013018 (rank : 77)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	942	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

KNTC2_MOUSE
NC score	0.012996 (rank : 78)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	692	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

GOGB1_HUMAN
NC score	0.012728 (rank : 79)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	2297	Shared Neighborhood Hits	36
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GOGA3_HUMAN
NC score	0.012044 (rank : 80)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	1317	Shared Neighborhood Hits	31
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HOOK2_MOUSE
NC score	0.010399 (rank : 81)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	736	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

GOGA3_MOUSE
NC score	0.009967 (rank : 82)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	1437	Shared Neighborhood Hits	31
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MYH9_MOUSE
NC score	0.009931 (rank : 83)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	1829	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PK3CB_MOUSE
NC score	0.009479 (rank : 84)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

MYH9_HUMAN
NC score	0.009318 (rank : 85)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SURF5_HUMAN
NC score	0.008988 (rank : 86)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q15528, O76072	Gene names	SURF5, SURF-5
Domain Architecture
Description	Surfeit locus protein 5.

BCN1_HUMAN
NC score	0.008902 (rank : 87)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	395	Shared Neighborhood Hits	20
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

LMNB1_MOUSE
NC score	0.008271 (rank : 88)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	719	Shared Neighborhood Hits	27
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MYH7_HUMAN
NC score	0.008137 (rank : 89)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	1559	Shared Neighborhood Hits	33
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

CENPE_HUMAN
NC score	0.008002 (rank : 90)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	2060	Shared Neighborhood Hits	34
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

BCL7A_HUMAN
NC score	0.007805 (rank : 91)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

LMNB1_HUMAN
NC score	0.007418 (rank : 92)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	714	Shared Neighborhood Hits	27
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

PCLO_HUMAN
NC score	0.006345 (rank : 93)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	2046	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BPA1_MOUSE
NC score	0.005586 (rank : 94)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	1477	Shared Neighborhood Hits	26
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

K2C4_MOUSE
NC score	0.005472 (rank : 95)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	521	Shared Neighborhood Hits	24
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

KIF5A_MOUSE
NC score	0.004992 (rank : 96)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	859	Shared Neighborhood Hits	24
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

PHF10_MOUSE
NC score	0.002995 (rank : 97)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

CTTB2_HUMAN
NC score	0.002097 (rank : 98)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	1061	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

5HT7R_HUMAN
NC score	-0.003812 (rank : 99)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	848	Shared Neighborhood Hits	2
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).