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Network neighborhood for query Sequence : SURF5_HUMAN

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SURF5_HUMAN
SwissProt Accessions	Q15528, O76072	Gene names	SURF5, SURF-5
Domain Architecture
Description	Surfeit locus protein 5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SURF5_HUMAN
θ value	3.11973e-85 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q15528, O76072	Gene names	SURF5, SURF-5
Domain Architecture
Description	Surfeit locus protein 5.

SURF5_MOUSE
θ value	8.83269e-64 (rank : 2)	NC score	0.990359 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q62276	Gene names	Surf5, Surf-5
Domain Architecture
Description	Surfeit locus protein 5.

ROCK2_HUMAN
θ value	0.0148317 (rank : 3)	NC score	0.040915 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	2073	Shared Neighborhood Hits	14
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	0.0563607 (rank : 4)	NC score	0.038824 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	2072	Shared Neighborhood Hits	14
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CI039_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.038500 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	1171	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ESCO1_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.058813 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

KS6C1_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.028408 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

REST_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.040210 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	1506	Shared Neighborhood Hits	13
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CENPE_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.024355 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	2060	Shared Neighborhood Hits	13
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

AKAP9_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.032783 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	1710	Shared Neighborhood Hits	13
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CASP_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.030405 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1131	Shared Neighborhood Hits	12
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.025909 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	1574	Shared Neighborhood Hits	12
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

OFD1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.032616 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	753	Shared Neighborhood Hits	11
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

REST_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.034333 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	1605	Shared Neighborhood Hits	13
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CNGA3_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.008988 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

Hits sorted by NC score

SURF5_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.11973e-85 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q15528, O76072	Gene names	SURF5, SURF-5
Domain Architecture
Description	Surfeit locus protein 5.

SURF5_MOUSE
NC score	0.990359 (rank : 2)	θ value	8.83269e-64 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q62276	Gene names	Surf5, Surf-5
Domain Architecture
Description	Surfeit locus protein 5.

ESCO1_HUMAN
NC score	0.058813 (rank : 3)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ROCK2_HUMAN
NC score	0.040915 (rank : 4)	θ value	0.0148317 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	2073	Shared Neighborhood Hits	14
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

REST_MOUSE
NC score	0.040210 (rank : 5)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	1506	Shared Neighborhood Hits	13
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ROCK2_MOUSE
NC score	0.038824 (rank : 6)	θ value	0.0563607 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	2072	Shared Neighborhood Hits	14
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CI039_HUMAN
NC score	0.038500 (rank : 7)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	1171	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

REST_HUMAN
NC score	0.034333 (rank : 8)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	1605	Shared Neighborhood Hits	13
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

AKAP9_HUMAN
NC score	0.032783 (rank : 9)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	1710	Shared Neighborhood Hits	13
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

OFD1_HUMAN
NC score	0.032616 (rank : 10)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	753	Shared Neighborhood Hits	11
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

CASP_HUMAN
NC score	0.030405 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1131	Shared Neighborhood Hits	12
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

KS6C1_MOUSE
NC score	0.028408 (rank : 12)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

CUTL1_HUMAN
NC score	0.025909 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	1574	Shared Neighborhood Hits	12
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CENPE_HUMAN
NC score	0.024355 (rank : 14)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	2060	Shared Neighborhood Hits	13
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CNGA3_MOUSE
NC score	0.008988 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).