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Network neighborhood for query Sequence : CNGA1_HUMAN

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CNGA1_HUMAN
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CNGA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	0 (rank : 2)	NC score	0.992417 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	0 (rank : 3)	NC score	0.986766 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_HUMAN
θ value	0 (rank : 4)	NC score	0.987430 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	125	Shared Neighborhood Hits	60
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	0 (rank : 5)	NC score	0.989347 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	84	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB1_HUMAN
θ value	1.60224e-81 (rank : 6)	NC score	0.928049 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	222	Shared Neighborhood Hits	54
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
θ value	3.0217e-80 (rank : 7)	NC score	0.931270 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	206	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	8.22888e-78 (rank : 8)	NC score	0.941495 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

HCN1_HUMAN
θ value	1.32601e-43 (rank : 9)	NC score	0.857454 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	1.32601e-43 (rank : 10)	NC score	0.853621 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	172	Shared Neighborhood Hits	47
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN4_HUMAN
θ value	5.03882e-43 (rank : 11)	NC score	0.836991 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	303	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	1.46607e-42 (rank : 12)	NC score	0.835294 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	284	Shared Neighborhood Hits	44
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_MOUSE
θ value	4.71619e-41 (rank : 13)	NC score	0.839707 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN2_HUMAN
θ value	3.99248e-40 (rank : 14)	NC score	0.830022 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	369	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN3_HUMAN
θ value	6.81017e-40 (rank : 15)	NC score	0.852233 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	1.98146e-39 (rank : 16)	NC score	0.852999 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

KCNH7_MOUSE
θ value	4.88048e-38 (rank : 17)	NC score	0.814247 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
θ value	1.20211e-36 (rank : 18)	NC score	0.813156 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	222	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH7_HUMAN
θ value	2.96089e-35 (rank : 19)	NC score	0.809367 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH8_HUMAN
θ value	8.61488e-35 (rank : 20)	NC score	0.808073 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH2_HUMAN
θ value	5.584e-34 (rank : 21)	NC score	0.812051 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	158	Shared Neighborhood Hits	38
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	5.584e-34 (rank : 22)	NC score	0.811951 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	165	Shared Neighborhood Hits	38
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH4_HUMAN
θ value	2.12192e-33 (rank : 23)	NC score	0.809193 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_HUMAN
θ value	4.00176e-32 (rank : 24)	NC score	0.800556 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH3_MOUSE
θ value	1.16434e-31 (rank : 25)	NC score	0.797803 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH5_MOUSE
θ value	1.16434e-31 (rank : 26)	NC score	0.800763 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_HUMAN
θ value	1.6813e-30 (rank : 27)	NC score	0.796538 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	1.6813e-30 (rank : 28)	NC score	0.796732 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH3_HUMAN
θ value	1.6813e-30 (rank : 29)	NC score	0.797659 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KGP2_HUMAN
θ value	0.00228821 (rank : 30)	NC score	0.068830 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	1023	Shared Neighborhood Hits	61
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
θ value	0.00228821 (rank : 31)	NC score	0.068393 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	1029	Shared Neighborhood Hits	57
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP1B_MOUSE
θ value	0.00298849 (rank : 32)	NC score	0.070896 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
θ value	0.00390308 (rank : 33)	NC score	0.070397 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	901	Shared Neighborhood Hits	54
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.070608 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

RBBP6_HUMAN
θ value	0.00390308 (rank : 35)	NC score	0.044110 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SMC4_MOUSE
θ value	0.00665767 (rank : 36)	NC score	0.060568 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	830	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

IWS1_MOUSE
θ value	0.0113563 (rank : 37)	NC score	0.036353 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	1258	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SMC4_HUMAN
θ value	0.0148317 (rank : 38)	NC score	0.054245 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	937	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

KAP1_HUMAN
θ value	0.0252991 (rank : 39)	NC score	0.235996 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.0563607 (rank : 40)	NC score	0.230538 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP3_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.198833 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	40	Shared Neighborhood Hits	32
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	0.0563607 (rank : 42)	NC score	0.204614 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

PHF20_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.053025 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	394	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

KAP2_MOUSE
θ value	0.0961366 (rank : 44)	NC score	0.193302 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP0_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.251726 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP2_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.189956 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

LEO1_HUMAN
θ value	0.125558 (rank : 47)	NC score	0.044180 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	958	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

KAP0_MOUSE
θ value	0.163984 (rank : 48)	NC score	0.234566 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

PHF20_MOUSE
θ value	0.163984 (rank : 49)	NC score	0.046923 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	513	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TRPM7_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.019098 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

ZN292_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.022701 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	918	Shared Neighborhood Hits	39
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

C8AP2_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.043788 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	548	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

RPGF3_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.062787 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

RPGF3_MOUSE
θ value	0.279714 (rank : 54)	NC score	0.069387 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

LARP1_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.040126 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	242	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

LEO1_MOUSE
θ value	0.47712 (rank : 56)	NC score	0.040377 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	946	Shared Neighborhood Hits	47
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ANR12_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.023824 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	1081	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

NIPBL_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.034332 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	1311	Shared Neighborhood Hits	68
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PACN2_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.013629 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PPIG_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.031273 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	670	Shared Neighborhood Hits	63
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SYCP1_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.020411 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	1313	Shared Neighborhood Hits	54
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TTK_HUMAN
θ value	0.62314 (rank : 62)	NC score	0.006809 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	816	Shared Neighborhood Hits	12
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

WDR47_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.015686 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

BPAEA_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.015594 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	1369	Shared Neighborhood Hits	49
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MPP8_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.028205 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	948	Shared Neighborhood Hits	63
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NASP_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.053160 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	709	Shared Neighborhood Hits	44
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SMC2_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.026629 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	1405	Shared Neighborhood Hits	54
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SYNC_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.026596 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

TRPM6_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.023862 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

HOOK1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.016513 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	942	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MYH3_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.014635 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	1660	Shared Neighborhood Hits	56
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NPBL_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.031843 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	1041	Shared Neighborhood Hits	56
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ARI5B_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.026533 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	328	Shared Neighborhood Hits	22
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

BAZ1B_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.022870 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	701	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CJ078_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.028029 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	559	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CT152_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.115950 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNQ3_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.038098 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MAP1A_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.042624 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	1626	Shared Neighborhood Hits	80
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MO4L2_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.015960 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

MYRIP_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.030884 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYRIP_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.026021 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SETD8_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.020239 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

TEX14_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.014602 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	1103	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ELOA1_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.036118 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	388	Shared Neighborhood Hits	24
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ITSN1_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.008627 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	1669	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KCNQ3_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.038586 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MATR3_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.038031 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	325	Shared Neighborhood Hits	20
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.038097 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	321	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

RRBP1_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.017106 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	1650	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CEBPZ_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.015757 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

CT152_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.151174 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	38	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

DYHC_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.016125 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	733	Shared Neighborhood Hits	35
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.016069 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	729	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

PQBP1_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.023040 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

SYNC_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.018835 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

TTC1_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.009698 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

GOGA4_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.015341 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	1939	Shared Neighborhood Hits	65
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MO4L2_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.017695 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MYH4_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.013331 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	1476	Shared Neighborhood Hits	51
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

PICK1_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.009419 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

SLK_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.008379 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	1798	Shared Neighborhood Hits	59
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TXND2_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.031308 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	828	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZCPW1_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.022069 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ADA30_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.004092 (rank : 157)
Query Neighborhood Hits	149	Target Neighborhood Hits	391	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

AFF4_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.030001 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	611	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CI093_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.014592 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	1088	Shared Neighborhood Hits	46
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

DMN_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.012621 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	690	Shared Neighborhood Hits	34
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

ESCO1_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.017551 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	361	Shared Neighborhood Hits	31
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

HXC10_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.002557 (rank : 158)
Query Neighborhood Hits	149	Target Neighborhood Hits	417	Shared Neighborhood Hits	12
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

INP4B_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.012093 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	O15327, Q6IN59, Q6PJB4	Gene names	INPP4B
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

MYH1_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.013521 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	1461	Shared Neighborhood Hits	49
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

SDCG1_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.026303 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

SLK_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.007935 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	1775	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SMC1A_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.025165 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	1346	Shared Neighborhood Hits	58
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.024793 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	1384	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

AFF4_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.027528 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	581	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ANR11_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.018923 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	1289	Shared Neighborhood Hits	65
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BRD7_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.006408 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

CBX5_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.007714 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CENPC_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.016779 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	154	Shared Neighborhood Hits	16
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CF060_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.012672 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	1270	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DMP1_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.032014 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	491	Shared Neighborhood Hits	41
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DNJC1_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.004786 (rank : 156)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

HXC10_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.002143 (rank : 159)
Query Neighborhood Hits	149	Target Neighborhood Hits	417	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

KCNQ4_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.020903 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

LUZP1_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.020178 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	940	Shared Neighborhood Hits	57
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MAP9_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.022982 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	518	Shared Neighborhood Hits	56
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MYH4_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.011986 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	1377	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH8_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.012787 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	1610	Shared Neighborhood Hits	54
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PARP1_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.010212 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

SM1L2_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.023765 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	1019	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

ZFP37_MOUSE
θ value	5.27518 (rank : 132)	NC score	-0.003474 (rank : 160)
Query Neighborhood Hits	149	Target Neighborhood Hits	906	Shared Neighborhood Hits	26
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ANR18_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.008698 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	1106	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ERCC6_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.013131 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

ITPR3_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.009800 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

SMC2_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.023273 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	1131	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SYCP1_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.018858 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	1456	Shared Neighborhood Hits	57
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TAOK1_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.005925 (rank : 154)
Query Neighborhood Hits	149	Target Neighborhood Hits	1734	Shared Neighborhood Hits	51
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.006042 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	1720	Shared Neighborhood Hits	53
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TEX14_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.010702 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	1333	Shared Neighborhood Hits	44
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TTF2_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.007650 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ZKSC1_HUMAN
θ value	6.88961 (rank : 142)	NC score	-0.003693 (rank : 161)
Query Neighborhood Hits	149	Target Neighborhood Hits	949	Shared Neighborhood Hits	18
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

AKAP2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.009935 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	507	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ARMC4_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.006397 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CJ006_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.008726 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

FACD2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.005774 (rank : 155)
Query Neighborhood Hits	149	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

MYH14_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.013843 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	1225	Shared Neighborhood Hits	53
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NIN_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.011403 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	1376	Shared Neighborhood Hits	52
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RFC1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.017253 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

KCNK2_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.066164 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.065719 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.063747 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.061878 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.055936 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.064576 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.061690 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.068145 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.054404 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.102609 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

RPGF4_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.066720 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.069911 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

Hits sorted by NC score

CNGA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.992417 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.989347 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	84	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.987430 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	125	Shared Neighborhood Hits	60
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
NC score	0.986766 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGB3_MOUSE
NC score	0.941495 (rank : 6)	θ value	8.22888e-78 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.931270 (rank : 7)	θ value	3.0217e-80 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	206	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.928049 (rank : 8)	θ value	1.60224e-81 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	222	Shared Neighborhood Hits	54
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

HCN1_HUMAN
NC score	0.857454 (rank : 9)	θ value	1.32601e-43 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.853621 (rank : 10)	θ value	1.32601e-43 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	172	Shared Neighborhood Hits	47
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
NC score	0.852999 (rank : 11)	θ value	1.98146e-39 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.852233 (rank : 12)	θ value	6.81017e-40 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.839707 (rank : 13)	θ value	4.71619e-41 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.836991 (rank : 14)	θ value	5.03882e-43 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	303	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.835294 (rank : 15)	θ value	1.46607e-42 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	284	Shared Neighborhood Hits	44
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.830022 (rank : 16)	θ value	3.99248e-40 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	369	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCNH7_MOUSE
NC score	0.814247 (rank : 17)	θ value	4.88048e-38 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH6_HUMAN
NC score	0.813156 (rank : 18)	θ value	1.20211e-36 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	222	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.812051 (rank : 19)	θ value	5.584e-34 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	158	Shared Neighborhood Hits	38
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.811951 (rank : 20)	θ value	5.584e-34 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	165	Shared Neighborhood Hits	38
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_HUMAN
NC score	0.809367 (rank : 21)	θ value	2.96089e-35 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH4_HUMAN
NC score	0.809193 (rank : 22)	θ value	2.12192e-33 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
NC score	0.808073 (rank : 23)	θ value	8.61488e-35 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH5_MOUSE
NC score	0.800763 (rank : 24)	θ value	1.16434e-31 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.800556 (rank : 25)	θ value	4.00176e-32 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH3_MOUSE
NC score	0.797803 (rank : 26)	θ value	1.16434e-31 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.797659 (rank : 27)	θ value	1.6813e-30 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH1_MOUSE
NC score	0.796732 (rank : 28)	θ value	1.6813e-30 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.796538 (rank : 29)	θ value	1.6813e-30 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KAP0_HUMAN
NC score	0.251726 (rank : 30)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP1_HUMAN
NC score	0.235996 (rank : 31)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP0_MOUSE
NC score	0.234566 (rank : 32)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_MOUSE
NC score	0.230538 (rank : 33)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP3_MOUSE
NC score	0.204614 (rank : 34)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.198833 (rank : 35)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	40	Shared Neighborhood Hits	32
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.193302 (rank : 36)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.189956 (rank : 37)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

CT152_MOUSE
NC score	0.151174 (rank : 38)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	38	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

CT152_HUMAN
NC score	0.115950 (rank : 39)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNKH_HUMAN
NC score	0.102609 (rank : 40)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KGP1B_MOUSE
NC score	0.070896 (rank : 41)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.070608 (rank : 42)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.070397 (rank : 43)	θ value	0.00390308 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	901	Shared Neighborhood Hits	54
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

RPGF4_MOUSE
NC score	0.069911 (rank : 44)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RPGF3_MOUSE
NC score	0.069387 (rank : 45)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

KGP2_HUMAN
NC score	0.068830 (rank : 46)	θ value	0.00228821 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	1023	Shared Neighborhood Hits	61
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
NC score	0.068393 (rank : 47)	θ value	0.00228821 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	1029	Shared Neighborhood Hits	57
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNKF_HUMAN
NC score	0.068145 (rank : 48)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

RPGF4_HUMAN
NC score	0.066720 (rank : 49)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

KCNK2_HUMAN
NC score	0.066164 (rank : 50)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.065719 (rank : 51)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.064576 (rank : 52)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	149	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_HUMAN
NC score	0.063747 (rank : 53)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

RPGF3_HUMAN
NC score	0.062787 (rank : 54)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

KCNK3_MOUSE
NC score	0.061878 (rank : 55)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.061690 (rank : 56)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	149	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

SMC4_MOUSE
NC score	0.060568 (rank : 57)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	830	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

KCNK4_HUMAN
NC score	0.055936 (rank : 58)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.054404 (rank : 59)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	149	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

SMC4_HUMAN
NC score	0.054245 (rank : 60)	θ value	0.0148317 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	937	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

NASP_HUMAN
NC score	0.053160 (rank : 61)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	709	Shared Neighborhood Hits	44
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PHF20_HUMAN
NC score	0.053025 (rank : 62)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	394	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
NC score	0.046923 (rank : 63)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	513	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

LEO1_HUMAN
NC score	0.044180 (rank : 64)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	958	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RBBP6_HUMAN
NC score	0.044110 (rank : 65)	θ value	0.00390308 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

C8AP2_HUMAN
NC score	0.043788 (rank : 66)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	548	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

MAP1A_HUMAN
NC score	0.042624 (rank : 67)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	1626	Shared Neighborhood Hits	80
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

LEO1_MOUSE
NC score	0.040377 (rank : 68)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	946	Shared Neighborhood Hits	47
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LARP1_HUMAN
NC score	0.040126 (rank : 69)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	242	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

KCNQ3_MOUSE
NC score	0.038586 (rank : 70)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.038098 (rank : 71)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MATR3_MOUSE
NC score	0.038097 (rank : 72)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	321	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MATR3_HUMAN
NC score	0.038031 (rank : 73)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	325	Shared Neighborhood Hits	20
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

IWS1_MOUSE
NC score	0.036353 (rank : 74)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	1258	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ELOA1_HUMAN
NC score	0.036118 (rank : 75)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	388	Shared Neighborhood Hits	24
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

NIPBL_HUMAN
NC score	0.034332 (rank : 76)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	1311	Shared Neighborhood Hits	68
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DMP1_HUMAN
NC score	0.032014 (rank : 77)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	491	Shared Neighborhood Hits	41
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

NPBL_MOUSE
NC score	0.031843 (rank : 78)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	1041	Shared Neighborhood Hits	56
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TXND2_MOUSE
NC score	0.031308 (rank : 79)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	828	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

PPIG_HUMAN
NC score	0.031273 (rank : 80)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	670	Shared Neighborhood Hits	63
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

MYRIP_HUMAN
NC score	0.030884 (rank : 81)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

AFF4_HUMAN
NC score	0.030001 (rank : 82)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	611	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

MPP8_HUMAN
NC score	0.028205 (rank : 83)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	948	Shared Neighborhood Hits	63
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CJ078_MOUSE
NC score	0.028029 (rank : 84)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	559	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

AFF4_MOUSE
NC score	0.027528 (rank : 85)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	581	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

SMC2_HUMAN
NC score	0.026629 (rank : 86)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	1405	Shared Neighborhood Hits	54
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SYNC_MOUSE
NC score	0.026596 (rank : 87)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

ARI5B_HUMAN
NC score	0.026533 (rank : 88)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	328	Shared Neighborhood Hits	22
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

SDCG1_MOUSE
NC score	0.026303 (rank : 89)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

MYRIP_MOUSE
NC score	0.026021 (rank : 90)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SMC1A_HUMAN
NC score	0.025165 (rank : 91)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	1346	Shared Neighborhood Hits	58
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.024793 (rank : 92)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	1384	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TRPM6_MOUSE
NC score	0.023862 (rank : 93)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

ANR12_HUMAN
NC score	0.023824 (rank : 94)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	1081	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SM1L2_HUMAN
NC score	0.023765 (rank : 95)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	1019	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC2_MOUSE
NC score	0.023273 (rank : 96)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	1131	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

PQBP1_MOUSE
NC score	0.023040 (rank : 97)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

MAP9_HUMAN
NC score	0.022982 (rank : 98)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	518	Shared Neighborhood Hits	56
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

BAZ1B_HUMAN
NC score	0.022870 (rank : 99)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	701	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

ZN292_HUMAN
NC score	0.022701 (rank : 100)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	918	Shared Neighborhood Hits	39
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

ZCPW1_MOUSE
NC score	0.022069 (rank : 101)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

KCNQ4_HUMAN
NC score	0.020903 (rank : 102)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

SYCP1_HUMAN
NC score	0.020411 (rank : 103)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	1313	Shared Neighborhood Hits	54
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SETD8_MOUSE
NC score	0.020239 (rank : 104)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

LUZP1_MOUSE
NC score	0.020178 (rank : 105)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	940	Shared Neighborhood Hits	57
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

TRPM7_HUMAN
NC score	0.019098 (rank : 106)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

ANR11_HUMAN
NC score	0.018923 (rank : 107)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	1289	Shared Neighborhood Hits	65
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

SYCP1_MOUSE
NC score	0.018858 (rank : 108)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	1456	Shared Neighborhood Hits	57
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNC_HUMAN
NC score	0.018835 (rank : 109)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

MO4L2_HUMAN
NC score	0.017695 (rank : 110)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

ESCO1_HUMAN
NC score	0.017551 (rank : 111)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	361	Shared Neighborhood Hits	31
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

RFC1_HUMAN
NC score	0.017253 (rank : 112)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RRBP1_MOUSE
NC score	0.017106 (rank : 113)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	1650	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CENPC_MOUSE
NC score	0.016779 (rank : 114)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	154	Shared Neighborhood Hits	16
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

HOOK1_HUMAN
NC score	0.016513 (rank : 115)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	942	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

DYHC_HUMAN
NC score	0.016125 (rank : 116)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	733	Shared Neighborhood Hits	35
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.016069 (rank : 117)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	729	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

MO4L2_MOUSE
NC score	0.015960 (rank : 118)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

CEBPZ_HUMAN
NC score	0.015757 (rank : 119)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

WDR47_HUMAN
NC score	0.015686 (rank : 120)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

BPAEA_HUMAN
NC score	0.015594 (rank : 121)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	1369	Shared Neighborhood Hits	49
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGA4_MOUSE
NC score	0.015341 (rank : 122)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	1939	Shared Neighborhood Hits	65
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH3_HUMAN
NC score	0.014635 (rank : 123)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	1660	Shared Neighborhood Hits	56
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TEX14_HUMAN
NC score	0.014602 (rank : 124)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	1103	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CI093_HUMAN
NC score	0.014592 (rank : 125)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	1088	Shared Neighborhood Hits	46
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

MYH14_MOUSE
NC score	0.013843 (rank : 126)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	1225	Shared Neighborhood Hits	53
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PACN2_MOUSE
NC score	0.013629 (rank : 127)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

MYH1_MOUSE
NC score	0.013521 (rank : 128)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	1461	Shared Neighborhood Hits	49
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
NC score	0.013331 (rank : 129)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	1476	Shared Neighborhood Hits	51
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

ERCC6_HUMAN
NC score	0.013131 (rank : 130)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

MYH8_HUMAN
NC score	0.012787 (rank : 131)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	1610	Shared Neighborhood Hits	54
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CF060_HUMAN
NC score	0.012672 (rank : 132)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	1270	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DMN_HUMAN
NC score	0.012621 (rank : 133)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	690	Shared Neighborhood Hits	34
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

INP4B_HUMAN
NC score	0.012093 (rank : 134)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	O15327, Q6IN59, Q6PJB4	Gene names	INPP4B
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

MYH4_HUMAN
NC score	0.011986 (rank : 135)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	1377	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

NIN_MOUSE
NC score	0.011403 (rank : 136)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	1376	Shared Neighborhood Hits	52
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

TEX14_MOUSE
NC score	0.010702 (rank : 137)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	1333	Shared Neighborhood Hits	44
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

PARP1_MOUSE
NC score	0.010212 (rank : 138)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

AKAP2_HUMAN
NC score	0.009935 (rank : 139)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	507	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ITPR3_HUMAN
NC score	0.009800 (rank : 140)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

TTC1_HUMAN
NC score	0.009698 (rank : 141)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

PICK1_MOUSE
NC score	0.009419 (rank : 142)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

CJ006_MOUSE
NC score	0.008726 (rank : 143)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

ANR18_HUMAN
NC score	0.008698 (rank : 144)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	1106	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ITSN1_MOUSE
NC score	0.008627 (rank : 145)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	1669	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SLK_MOUSE
NC score	0.008379 (rank : 146)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	1798	Shared Neighborhood Hits	59
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SLK_HUMAN
NC score	0.007935 (rank : 147)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	1775	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

CBX5_HUMAN
NC score	0.007714 (rank : 148)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

TTF2_MOUSE
NC score	0.007650 (rank : 149)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TTK_HUMAN
NC score	0.006809 (rank : 150)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	816	Shared Neighborhood Hits	12
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

BRD7_MOUSE
NC score	0.006408 (rank : 151)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

ARMC4_HUMAN
NC score	0.006397 (rank : 152)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

TAOK1_MOUSE
NC score	0.006042 (rank : 153)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	1720	Shared Neighborhood Hits	53
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK1_HUMAN
NC score	0.005925 (rank : 154)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	1734	Shared Neighborhood Hits	51
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

FACD2_HUMAN
NC score	0.005774 (rank : 155)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

DNJC1_MOUSE
NC score	0.004786 (rank : 156)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

ADA30_HUMAN
NC score	0.004092 (rank : 157)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	391	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

HXC10_MOUSE
NC score	0.002557 (rank : 158)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	417	Shared Neighborhood Hits	12
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

HXC10_HUMAN
NC score	0.002143 (rank : 159)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	417	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

ZFP37_MOUSE
NC score	-0.003474 (rank : 160)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	906	Shared Neighborhood Hits	26
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZKSC1_HUMAN
NC score	-0.003693 (rank : 161)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	949	Shared Neighborhood Hits	18
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).