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Network neighborhood for query Sequence : PARP1_MOUSE

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PARP1_MOUSE
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARP1_HUMAN
θ value	0 (rank : 1)	NC score	0.987324 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP2_MOUSE
θ value	6.0463e-105 (rank : 3)	NC score	0.907493 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP2_HUMAN
θ value	2.80862e-102 (rank : 4)	NC score	0.910424 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP3_HUMAN
θ value	4.53632e-60 (rank : 5)	NC score	0.876410 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PARP4_HUMAN
θ value	4.43474e-23 (rank : 6)	NC score	0.548923 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

DNL3_HUMAN
θ value	2.61198e-07 (rank : 7)	NC score	0.207811 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
θ value	7.59969e-07 (rank : 8)	NC score	0.205467 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

TNKS2_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.063699 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
θ value	0.00869519 (rank : 10)	NC score	0.067882 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	477	Shared Neighborhood Hits	13
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

RSF1_HUMAN
θ value	0.0330416 (rank : 11)	NC score	0.049046 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	539	Shared Neighborhood Hits	25
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SPC25_HUMAN
θ value	0.0563607 (rank : 12)	NC score	0.084925 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

RFC1_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.078719 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

CN145_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.033034 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	1196	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

GLE1_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.061557 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	445	Shared Neighborhood Hits	27
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

PARP6_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.140392 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
θ value	0.163984 (rank : 17)	NC score	0.140328 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP8_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.140123 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
θ value	0.163984 (rank : 19)	NC score	0.139797 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

KIF2C_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.021789 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

PEX14_MOUSE
θ value	0.21417 (rank : 21)	NC score	0.061819 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

BICD2_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.036016 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	864	Shared Neighborhood Hits	35
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

RB6I2_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.031201 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	1584	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RFC1_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.069430 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	352	Shared Neighborhood Hits	20
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

FA48A_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.040842 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

CTRO_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.014394 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	2344	Shared Neighborhood Hits	43
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

TOPB1_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.043679 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

ISK5_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.039680 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

GOGA6_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.031487 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	1007	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NEB1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.027912 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	829	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

BICD2_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.034343 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	856	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CYLN2_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.032105 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	1002	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

FLNB_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.022395 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

THAP2_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.042041 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D305	Gene names	Thap2
Domain Architecture
Description	THAP domain-containing protein 2.

BRE1B_MOUSE
θ value	1.38821 (rank : 35)	NC score	0.030884 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	970	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CAF1A_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.037349 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	750	Shared Neighborhood Hits	35
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CYLN2_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.030765 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	1004	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

GCC2_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.031926 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	1558	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

PEX14_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.052411 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

RBP24_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.031949 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	1559	Shared Neighborhood Hits	43
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SYNE2_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.028752 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	1323	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TTC5_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.039004 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LG4	Gene names	Ttc5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

ANR11_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.024844 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	1289	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CLOCK_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.018144 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

DP13A_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.025811 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

ENKUR_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.035337 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

CTRO_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.012861 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	2092	Shared Neighborhood Hits	42
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DP13A_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.024477 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

FLNB_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.020835 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

CLOCK_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.016903 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

DDX27_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.005717 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

FOXN4_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.008441 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	248	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

GOGA4_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.024996 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	2034	Shared Neighborhood Hits	50
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

JHD2C_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.019533 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MAP1B_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.023095 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	977	Shared Neighborhood Hits	28
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PLCE_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.019780 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUQ2, Q8IZ47, Q9BQG4	Gene names	AGPAT5
Domain Architecture
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase-epsilon) (LPAAT-epsilon) (1-acylglycerol-3-phosphate O-acyltransferase 5).

RB6I2_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.028533 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	1433	Shared Neighborhood Hits	43
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

STB5L_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.022761 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

TTC5_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.034669 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N0Z6	Gene names	TTC5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

JAD1A_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.020082 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	328	Shared Neighborhood Hits	17
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

MATR3_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.016393 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MMRN2_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.022619 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	400	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MUSC_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.012968 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

OPTN_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.024727 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	1120	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

P80C_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.026657 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

PAR14_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.045132 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PARPT_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.056935 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.070769 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

RL7A_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.027336 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P12970, Q91YM3	Gene names	Rpl7a, Surf-3, Surf3
Domain Architecture
Description	60S ribosomal protein L7a (Surfeit locus protein 3).

STB5L_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.022023 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

XL3A_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.033299 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

BRE1B_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.029347 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	1040	Shared Neighborhood Hits	34
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CNGA1_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.010212 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.010194 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CROCC_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.025996 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	1409	Shared Neighborhood Hits	40
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.026008 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	1460	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CYLC2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.021361 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DACH1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.013933 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	214	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

K1196_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.007681 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	618	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

LYRIC_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.016595 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

OFD1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.035088 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	753	Shared Neighborhood Hits	36
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

PRP40_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.019705 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	442	Shared Neighborhood Hits	23
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

BRE1A_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.030869 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	1071	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

DEN2A_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.007219 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

ITSN1_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.013917 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	1669	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MOES_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.016120 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	923	Shared Neighborhood Hits	37
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RL7A_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.023788 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P62424, P11518	Gene names	RPL7A, SURF-3, SURF3
Domain Architecture
Description	60S ribosomal protein L7a (Surfeit locus protein 3) (PLA-X polypeptide).

TRFM_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.009188 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P08582, Q9BQE2	Gene names	MFI2, MAP97
Domain Architecture
Description	Melanotransferrin precursor (Melanoma-associated antigen p97) (CD228 antigen).

TXND2_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.009995 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	793	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CAC1F_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.006830 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.007271 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CCD21_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.021194 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	1135	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CL011_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.011023 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVM9, Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5	Gene names	C12orf11
Domain Architecture	No domain graphic available
Description	Protein C12orf11 (Sarcoma antigen NY-SAR-95).

ENKUR_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.024463 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

MYO10_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.008309 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	920	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

REST_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.024951 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	1605	Shared Neighborhood Hits	47
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SPTB2_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.023109 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	748	Shared Neighborhood Hits	32
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.023651 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	770	Shared Neighborhood Hits	34
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

STXB5_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.019211 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STXB5_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.019317 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

SYCP1_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.022835 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	1313	Shared Neighborhood Hits	46
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ZRF1_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.020379 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	457	Shared Neighborhood Hits	28
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

LHR2A_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.051535 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

LHR2A_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.054855 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

Hits sorted by NC score

PARP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP1_HUMAN
NC score	0.987324 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP2_HUMAN
NC score	0.910424 (rank : 3)	θ value	2.80862e-102 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
NC score	0.907493 (rank : 4)	θ value	6.0463e-105 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP3_HUMAN
NC score	0.876410 (rank : 5)	θ value	4.53632e-60 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PARP4_HUMAN
NC score	0.548923 (rank : 6)	θ value	4.43474e-23 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

DNL3_HUMAN
NC score	0.207811 (rank : 7)	θ value	2.61198e-07 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
NC score	0.205467 (rank : 8)	θ value	7.59969e-07 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

PARP6_HUMAN
NC score	0.140392 (rank : 9)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
NC score	0.140328 (rank : 10)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP8_HUMAN
NC score	0.140123 (rank : 11)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
NC score	0.139797 (rank : 12)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

SPC25_HUMAN
NC score	0.084925 (rank : 13)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

RFC1_MOUSE
NC score	0.078719 (rank : 14)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

PARPT_MOUSE
NC score	0.070769 (rank : 15)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

RFC1_HUMAN
NC score	0.069430 (rank : 16)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	352	Shared Neighborhood Hits	20
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

TNKS1_HUMAN
NC score	0.067882 (rank : 17)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	477	Shared Neighborhood Hits	13
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.063699 (rank : 18)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PEX14_MOUSE
NC score	0.061819 (rank : 19)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

GLE1_HUMAN
NC score	0.061557 (rank : 20)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	445	Shared Neighborhood Hits	27
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

PARPT_HUMAN
NC score	0.056935 (rank : 21)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

LHR2A_MOUSE
NC score	0.054855 (rank : 22)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

PEX14_HUMAN
NC score	0.052411 (rank : 23)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

LHR2A_HUMAN
NC score	0.051535 (rank : 24)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

RSF1_HUMAN
NC score	0.049046 (rank : 25)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	539	Shared Neighborhood Hits	25
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PAR14_MOUSE
NC score	0.045132 (rank : 26)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

TOPB1_HUMAN
NC score	0.043679 (rank : 27)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

THAP2_MOUSE
NC score	0.042041 (rank : 28)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D305	Gene names	Thap2
Domain Architecture
Description	THAP domain-containing protein 2.

FA48A_HUMAN
NC score	0.040842 (rank : 29)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

ISK5_HUMAN
NC score	0.039680 (rank : 30)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

TTC5_MOUSE
NC score	0.039004 (rank : 31)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LG4	Gene names	Ttc5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

CAF1A_HUMAN
NC score	0.037349 (rank : 32)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	750	Shared Neighborhood Hits	35
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

BICD2_MOUSE
NC score	0.036016 (rank : 33)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	864	Shared Neighborhood Hits	35
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

ENKUR_HUMAN
NC score	0.035337 (rank : 34)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

OFD1_HUMAN
NC score	0.035088 (rank : 35)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	753	Shared Neighborhood Hits	36
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

TTC5_HUMAN
NC score	0.034669 (rank : 36)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N0Z6	Gene names	TTC5
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 5 (TPR repeat protein 5).

BICD2_HUMAN
NC score	0.034343 (rank : 37)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	856	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

XL3A_MOUSE
NC score	0.033299 (rank : 38)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

CN145_HUMAN
NC score	0.033034 (rank : 39)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	1196	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CYLN2_MOUSE
NC score	0.032105 (rank : 40)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	1002	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

RBP24_HUMAN
NC score	0.031949 (rank : 41)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	1559	Shared Neighborhood Hits	43
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.031926 (rank : 42)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	1558	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA6_HUMAN
NC score	0.031487 (rank : 43)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	1007	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

RB6I2_HUMAN
NC score	0.031201 (rank : 44)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	1584	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

BRE1B_MOUSE
NC score	0.030884 (rank : 45)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	970	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1A_HUMAN
NC score	0.030869 (rank : 46)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	1071	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CYLN2_HUMAN
NC score	0.030765 (rank : 47)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	1004	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

BRE1B_HUMAN
NC score	0.029347 (rank : 48)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	1040	Shared Neighborhood Hits	34
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

SYNE2_HUMAN
NC score	0.028752 (rank : 49)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	1323	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

RB6I2_MOUSE
NC score	0.028533 (rank : 50)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	1433	Shared Neighborhood Hits	43
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

NEB1_HUMAN
NC score	0.027912 (rank : 51)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	829	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

RL7A_MOUSE
NC score	0.027336 (rank : 52)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P12970, Q91YM3	Gene names	Rpl7a, Surf-3, Surf3
Domain Architecture
Description	60S ribosomal protein L7a (Surfeit locus protein 3).

P80C_HUMAN
NC score	0.026657 (rank : 53)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

CROCC_MOUSE
NC score	0.026008 (rank : 54)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	1460	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_HUMAN
NC score	0.025996 (rank : 55)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	1409	Shared Neighborhood Hits	40
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DP13A_HUMAN
NC score	0.025811 (rank : 56)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

GOGA4_HUMAN
NC score	0.024996 (rank : 57)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	2034	Shared Neighborhood Hits	50
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

REST_HUMAN
NC score	0.024951 (rank : 58)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	1605	Shared Neighborhood Hits	47
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ANR11_HUMAN
NC score	0.024844 (rank : 59)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	1289	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

OPTN_MOUSE
NC score	0.024727 (rank : 60)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	1120	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

DP13A_MOUSE
NC score	0.024477 (rank : 61)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

ENKUR_MOUSE
NC score	0.024463 (rank : 62)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

RL7A_HUMAN
NC score	0.023788 (rank : 63)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P62424, P11518	Gene names	RPL7A, SURF-3, SURF3
Domain Architecture
Description	60S ribosomal protein L7a (Surfeit locus protein 3) (PLA-X polypeptide).

SPTB2_MOUSE
NC score	0.023651 (rank : 64)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	770	Shared Neighborhood Hits	34
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_HUMAN
NC score	0.023109 (rank : 65)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	748	Shared Neighborhood Hits	32
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

MAP1B_MOUSE
NC score	0.023095 (rank : 66)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	977	Shared Neighborhood Hits	28
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SYCP1_HUMAN
NC score	0.022835 (rank : 67)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	1313	Shared Neighborhood Hits	46
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

STB5L_MOUSE
NC score	0.022761 (rank : 68)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

MMRN2_HUMAN
NC score	0.022619 (rank : 69)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	400	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

FLNB_HUMAN
NC score	0.022395 (rank : 70)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

STB5L_HUMAN
NC score	0.022023 (rank : 71)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

KIF2C_HUMAN
NC score	0.021789 (rank : 72)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

CYLC2_HUMAN
NC score	0.021361 (rank : 73)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

CCD21_MOUSE
NC score	0.021194 (rank : 74)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	1135	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

FLNB_MOUSE
NC score	0.020835 (rank : 75)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

ZRF1_HUMAN
NC score	0.020379 (rank : 76)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	457	Shared Neighborhood Hits	28
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

JAD1A_HUMAN
NC score	0.020082 (rank : 77)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	328	Shared Neighborhood Hits	17
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

PLCE_HUMAN
NC score	0.019780 (rank : 78)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUQ2, Q8IZ47, Q9BQG4	Gene names	AGPAT5
Domain Architecture
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase-epsilon) (LPAAT-epsilon) (1-acylglycerol-3-phosphate O-acyltransferase 5).

PRP40_HUMAN
NC score	0.019705 (rank : 79)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	442	Shared Neighborhood Hits	23
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

JHD2C_MOUSE
NC score	0.019533 (rank : 80)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

STXB5_MOUSE
NC score	0.019317 (rank : 81)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STXB5_HUMAN
NC score	0.019211 (rank : 82)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

CLOCK_MOUSE
NC score	0.018144 (rank : 83)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.016903 (rank : 84)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

LYRIC_MOUSE
NC score	0.016595 (rank : 85)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

MATR3_HUMAN
NC score	0.016393 (rank : 86)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MOES_MOUSE
NC score	0.016120 (rank : 87)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	923	Shared Neighborhood Hits	37
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CTRO_MOUSE
NC score	0.014394 (rank : 88)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	2344	Shared Neighborhood Hits	43
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DACH1_HUMAN
NC score	0.013933 (rank : 89)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	214	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

ITSN1_MOUSE
NC score	0.013917 (rank : 90)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	1669	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MUSC_HUMAN
NC score	0.012968 (rank : 91)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

CTRO_HUMAN
NC score	0.012861 (rank : 92)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	2092	Shared Neighborhood Hits	42
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CL011_HUMAN
NC score	0.011023 (rank : 93)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVM9, Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5	Gene names	C12orf11
Domain Architecture	No domain graphic available
Description	Protein C12orf11 (Sarcoma antigen NY-SAR-95).

CNGA1_HUMAN
NC score	0.010212 (rank : 94)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.010194 (rank : 95)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

TXND2_HUMAN
NC score	0.009995 (rank : 96)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	793	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TRFM_HUMAN
NC score	0.009188 (rank : 97)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P08582, Q9BQE2	Gene names	MFI2, MAP97
Domain Architecture
Description	Melanotransferrin precursor (Melanoma-associated antigen p97) (CD228 antigen).

FOXN4_HUMAN
NC score	0.008441 (rank : 98)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	248	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

MYO10_HUMAN
NC score	0.008309 (rank : 99)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	920	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

K1196_HUMAN
NC score	0.007681 (rank : 100)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	618	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

CAC1F_MOUSE
NC score	0.007271 (rank : 101)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

DEN2A_MOUSE
NC score	0.007219 (rank : 102)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

CAC1F_HUMAN
NC score	0.006830 (rank : 103)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

DDX27_MOUSE
NC score	0.005717 (rank : 104)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).