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Network neighborhood for query Sequence : HCN1_MOUSE

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HCN1_MOUSE
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.990656 (rank : 2)
Query Neighborhood Hits	172	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	172	Target Neighborhood Hits	172	Shared Neighborhood Hits	172
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.960621 (rank : 8)
Query Neighborhood Hits	172	Target Neighborhood Hits	369	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.970705 (rank : 5)
Query Neighborhood Hits	172	Target Neighborhood Hits	278	Shared Neighborhood Hits	61
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	0 (rank : 5)	NC score	0.984889 (rank : 4)
Query Neighborhood Hits	172	Target Neighborhood Hits	99	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	0 (rank : 6)	NC score	0.985210 (rank : 3)
Query Neighborhood Hits	172	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_HUMAN
θ value	0 (rank : 7)	NC score	0.969226 (rank : 6)
Query Neighborhood Hits	172	Target Neighborhood Hits	303	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	0 (rank : 8)	NC score	0.967669 (rank : 7)
Query Neighborhood Hits	172	Target Neighborhood Hits	284	Shared Neighborhood Hits	64
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA2_MOUSE
θ value	1.28137e-46 (rank : 9)	NC score	0.864423 (rank : 9)
Query Neighborhood Hits	172	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_MOUSE
θ value	2.67181e-44 (rank : 10)	NC score	0.852750 (rank : 12)
Query Neighborhood Hits	172	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
θ value	1.32601e-43 (rank : 11)	NC score	0.853621 (rank : 11)
Query Neighborhood Hits	172	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	8.59492e-43 (rank : 12)	NC score	0.857414 (rank : 10)
Query Neighborhood Hits	172	Target Neighborhood Hits	84	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	1.79215e-40 (rank : 13)	NC score	0.851416 (rank : 13)
Query Neighborhood Hits	172	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

KCNH6_HUMAN
θ value	1.98146e-39 (rank : 14)	NC score	0.808345 (rank : 17)
Query Neighborhood Hits	172	Target Neighborhood Hits	222	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_MOUSE
θ value	2.19075e-38 (rank : 15)	NC score	0.804661 (rank : 19)
Query Neighborhood Hits	172	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH5_HUMAN
θ value	2.19075e-38 (rank : 16)	NC score	0.795328 (rank : 23)
Query Neighborhood Hits	172	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	2.19075e-38 (rank : 17)	NC score	0.795665 (rank : 22)
Query Neighborhood Hits	172	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH2_HUMAN
θ value	2.86122e-38 (rank : 18)	NC score	0.804862 (rank : 18)
Query Neighborhood Hits	172	Target Neighborhood Hits	158	Shared Neighborhood Hits	46
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_MOUSE
θ value	2.86122e-38 (rank : 19)	NC score	0.804142 (rank : 20)
Query Neighborhood Hits	172	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
θ value	5.96599e-36 (rank : 20)	NC score	0.799298 (rank : 21)
Query Neighborhood Hits	172	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH1_HUMAN
θ value	8.61488e-35 (rank : 21)	NC score	0.789071 (rank : 27)
Query Neighborhood Hits	172	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	8.61488e-35 (rank : 22)	NC score	0.789243 (rank : 26)
Query Neighborhood Hits	172	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

CNGB1_HUMAN
θ value	2.50655e-34 (rank : 23)	NC score	0.825958 (rank : 15)
Query Neighborhood Hits	172	Target Neighborhood Hits	222	Shared Neighborhood Hits	55
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH4_HUMAN
θ value	3.61944e-33 (rank : 24)	NC score	0.794930 (rank : 24)
Query Neighborhood Hits	172	Target Neighborhood Hits	177	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
θ value	5.22648e-32 (rank : 25)	NC score	0.789504 (rank : 25)
Query Neighborhood Hits	172	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

CNGB3_MOUSE
θ value	1.16434e-31 (rank : 26)	NC score	0.832592 (rank : 14)
Query Neighborhood Hits	172	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
θ value	1.85889e-29 (rank : 27)	NC score	0.816657 (rank : 16)
Query Neighborhood Hits	172	Target Neighborhood Hits	206	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH3_HUMAN
θ value	2.42779e-29 (rank : 28)	NC score	0.777668 (rank : 28)
Query Neighborhood Hits	172	Target Neighborhood Hits	148	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	2.42779e-29 (rank : 29)	NC score	0.777258 (rank : 29)
Query Neighborhood Hits	172	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
θ value	1.87187e-05 (rank : 30)	NC score	0.299784 (rank : 30)
Query Neighborhood Hits	172	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KGP2_MOUSE
θ value	5.44631e-05 (rank : 31)	NC score	0.075050 (rank : 44)
Query Neighborhood Hits	172	Target Neighborhood Hits	1029	Shared Neighborhood Hits	52
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
θ value	9.29e-05 (rank : 32)	NC score	0.074911 (rank : 45)
Query Neighborhood Hits	172	Target Neighborhood Hits	1023	Shared Neighborhood Hits	49
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KAP3_HUMAN
θ value	0.00228821 (rank : 33)	NC score	0.231562 (rank : 37)
Query Neighborhood Hits	172	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	0.00228821 (rank : 34)	NC score	0.236955 (rank : 36)
Query Neighborhood Hits	172	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KGP1A_HUMAN
θ value	0.00228821 (rank : 35)	NC score	0.075329 (rank : 43)
Query Neighborhood Hits	172	Target Neighborhood Hits	901	Shared Neighborhood Hits	52
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00228821 (rank : 36)	NC score	0.075569 (rank : 42)
Query Neighborhood Hits	172	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KAP2_HUMAN
θ value	0.00390308 (rank : 37)	NC score	0.241766 (rank : 35)
Query Neighborhood Hits	172	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	0.00390308 (rank : 38)	NC score	0.244998 (rank : 34)
Query Neighborhood Hits	172	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KGP1B_MOUSE
θ value	0.00390308 (rank : 39)	NC score	0.075570 (rank : 41)
Query Neighborhood Hits	172	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KAP1_HUMAN
θ value	0.00869519 (rank : 40)	NC score	0.262424 (rank : 32)
Query Neighborhood Hits	172	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.259359 (rank : 33)
Query Neighborhood Hits	172	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

R3HD2_MOUSE
θ value	0.00869519 (rank : 42)	NC score	0.057254 (rank : 53)
Query Neighborhood Hits	172	Target Neighborhood Hits	397	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CCR3_MOUSE
θ value	0.0148317 (rank : 43)	NC score	0.016075 (rank : 108)
Query Neighborhood Hits	172	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

KAP0_MOUSE
θ value	0.0193708 (rank : 44)	NC score	0.269155 (rank : 31)
Query Neighborhood Hits	172	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

INVO_HUMAN
θ value	0.0252991 (rank : 45)	NC score	0.035666 (rank : 75)
Query Neighborhood Hits	172	Target Neighborhood Hits	636	Shared Neighborhood Hits	46
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

RPTN_HUMAN
θ value	0.0252991 (rank : 46)	NC score	0.028783 (rank : 82)
Query Neighborhood Hits	172	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

MLL3_HUMAN
θ value	0.0563607 (rank : 47)	NC score	0.040273 (rank : 66)
Query Neighborhood Hits	172	Target Neighborhood Hits	1644	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SIA7A_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.023298 (rank : 93)
Query Neighborhood Hits	172	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

ADDB_MOUSE
θ value	0.0736092 (rank : 49)	NC score	0.020584 (rank : 98)
Query Neighborhood Hits	172	Target Neighborhood Hits	574	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

KI21A_MOUSE
θ value	0.0961366 (rank : 50)	NC score	0.012236 (rank : 133)
Query Neighborhood Hits	172	Target Neighborhood Hits	1317	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

STK10_MOUSE
θ value	0.0961366 (rank : 51)	NC score	0.012544 (rank : 132)
Query Neighborhood Hits	172	Target Neighborhood Hits	2132	Shared Neighborhood Hits	68
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

UBP2L_HUMAN
θ value	0.125558 (rank : 52)	NC score	0.039190 (rank : 68)
Query Neighborhood Hits	172	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

NFAT5_HUMAN
θ value	0.163984 (rank : 53)	NC score	0.028034 (rank : 85)
Query Neighborhood Hits	172	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

RGS3_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.040789 (rank : 64)
Query Neighborhood Hits	172	Target Neighborhood Hits	1375	Shared Neighborhood Hits	38
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

INVO_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.042889 (rank : 63)
Query Neighborhood Hits	172	Target Neighborhood Hits	474	Shared Neighborhood Hits	51
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

SYPH_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.020445 (rank : 99)
Query Neighborhood Hits	172	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P08247, Q6P2F7	Gene names	SYP
Domain Architecture
Description	Synaptophysin (Major synaptic vesicle protein p38).

KCNS3_HUMAN
θ value	0.279714 (rank : 57)	NC score	0.016998 (rank : 107)
Query Neighborhood Hits	172	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

MRCKB_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.012797 (rank : 129)
Query Neighborhood Hits	172	Target Neighborhood Hits	2239	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NCOA2_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.033318 (rank : 78)
Query Neighborhood Hits	172	Target Neighborhood Hits	281	Shared Neighborhood Hits	23
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

HAP1_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.025062 (rank : 89)
Query Neighborhood Hits	172	Target Neighborhood Hits	606	Shared Neighborhood Hits	42
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

RING1_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.018022 (rank : 102)
Query Neighborhood Hits	172	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RPTN_MOUSE
θ value	0.365318 (rank : 62)	NC score	0.020798 (rank : 97)
Query Neighborhood Hits	172	Target Neighborhood Hits	650	Shared Neighborhood Hits	35
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

DCP1B_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.039655 (rank : 67)
Query Neighborhood Hits	172	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

HGS_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.022646 (rank : 95)
Query Neighborhood Hits	172	Target Neighborhood Hits	517	Shared Neighborhood Hits	32
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.023320 (rank : 92)
Query Neighborhood Hits	172	Target Neighborhood Hits	589	Shared Neighborhood Hits	33
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

NFAT5_MOUSE
θ value	0.47712 (rank : 66)	NC score	0.023679 (rank : 91)
Query Neighborhood Hits	172	Target Neighborhood Hits	162	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

TARA_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.035743 (rank : 74)
Query Neighborhood Hits	172	Target Neighborhood Hits	1626	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

UBP10_MOUSE
θ value	0.47712 (rank : 68)	NC score	0.020935 (rank : 96)
Query Neighborhood Hits	172	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP2L_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.035412 (rank : 76)
Query Neighborhood Hits	172	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

AMOL1_MOUSE
θ value	0.62314 (rank : 70)	NC score	0.017730 (rank : 104)
Query Neighborhood Hits	172	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

C8AP2_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.031915 (rank : 79)
Query Neighborhood Hits	172	Target Neighborhood Hits	548	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

EVX2_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.007477 (rank : 161)
Query Neighborhood Hits	172	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q03828	Gene names	EVX2
Domain Architecture
Description	Homeobox even-skipped homolog protein 2 (EVX-2).

EVX2_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.007511 (rank : 160)
Query Neighborhood Hits	172	Target Neighborhood Hits	327	Shared Neighborhood Hits	5
SwissProt Accessions	P49749	Gene names	Evx2, Evx-2
Domain Architecture
Description	Homeobox even-skipped homolog protein 2 (EVX-2).

ITSN1_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.014184 (rank : 121)
Query Neighborhood Hits	172	Target Neighborhood Hits	1669	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SRRM2_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.053887 (rank : 56)
Query Neighborhood Hits	172	Target Neighborhood Hits	1470	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

EMSY_MOUSE
θ value	0.813845 (rank : 76)	NC score	0.040334 (rank : 65)
Query Neighborhood Hits	172	Target Neighborhood Hits	294	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

KI21A_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.011210 (rank : 142)
Query Neighborhood Hits	172	Target Neighborhood Hits	1543	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

NPAS2_HUMAN
θ value	0.813845 (rank : 78)	NC score	0.014261 (rank : 120)
Query Neighborhood Hits	172	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

ACINU_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.026590 (rank : 87)
Query Neighborhood Hits	172	Target Neighborhood Hits	828	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

HAP1_MOUSE
θ value	1.06291 (rank : 80)	NC score	0.024602 (rank : 90)
Query Neighborhood Hits	172	Target Neighborhood Hits	388	Shared Neighborhood Hits	25
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

KCNN3_MOUSE
θ value	1.06291 (rank : 81)	NC score	0.020338 (rank : 100)
Query Neighborhood Hits	172	Target Neighborhood Hits	171	Shared Neighborhood Hits	28
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

MRCKB_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.012196 (rank : 135)
Query Neighborhood Hits	172	Target Neighborhood Hits	2180	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RGNEF_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.017271 (rank : 105)
Query Neighborhood Hits	172	Target Neighborhood Hits	641	Shared Neighborhood Hits	44
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

AKAP9_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.013602 (rank : 125)
Query Neighborhood Hits	172	Target Neighborhood Hits	1710	Shared Neighborhood Hits	61
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CT152_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.146894 (rank : 38)
Query Neighborhood Hits	172	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

FBLN2_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.003326 (rank : 177)
Query Neighborhood Hits	172	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ITSN1_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.015637 (rank : 111)
Query Neighborhood Hits	172	Target Neighborhood Hits	1757	Shared Neighborhood Hits	65
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KCNQ3_HUMAN
θ value	1.38821 (rank : 88)	NC score	0.037576 (rank : 72)
Query Neighborhood Hits	172	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.038291 (rank : 70)
Query Neighborhood Hits	172	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

STK10_HUMAN
θ value	1.38821 (rank : 90)	NC score	0.011580 (rank : 140)
Query Neighborhood Hits	172	Target Neighborhood Hits	1921	Shared Neighborhood Hits	60
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZEP1_MOUSE
θ value	1.38821 (rank : 91)	NC score	0.001801 (rank : 182)
Query Neighborhood Hits	172	Target Neighborhood Hits	1063	Shared Neighborhood Hits	20
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ASPP2_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.012226 (rank : 134)
Query Neighborhood Hits	172	Target Neighborhood Hits	1156	Shared Neighborhood Hits	59
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

DESP_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.010790 (rank : 144)
Query Neighborhood Hits	172	Target Neighborhood Hits	1470	Shared Neighborhood Hits	54
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EMSY_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.033498 (rank : 77)
Query Neighborhood Hits	172	Target Neighborhood Hits	296	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

HDAC4_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.012048 (rank : 137)
Query Neighborhood Hits	172	Target Neighborhood Hits	390	Shared Neighborhood Hits	34
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

LARP4_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.013828 (rank : 123)
Query Neighborhood Hits	172	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

NKX32_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.003652 (rank : 176)
Query Neighborhood Hits	172	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	P78367	Gene names	BAPX1, NKX3B
Domain Architecture
Description	Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1).

OSB10_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.008059 (rank : 157)
Query Neighborhood Hits	172	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

AHTF1_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.015361 (rank : 113)
Query Neighborhood Hits	172	Target Neighborhood Hits	286	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

ANK2_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.007214 (rank : 162)
Query Neighborhood Hits	172	Target Neighborhood Hits	1615	Shared Neighborhood Hits	49
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BSN_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.053383 (rank : 57)
Query Neighborhood Hits	172	Target Neighborhood Hits	2057	Shared Neighborhood Hits	85
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CSKI2_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.006974 (rank : 164)
Query Neighborhood Hits	172	Target Neighborhood Hits	812	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ELF1_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.006437 (rank : 167)
Query Neighborhood Hits	172	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

LAP2_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.001886 (rank : 180)
Query Neighborhood Hits	172	Target Neighborhood Hits	499	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MYO5B_HUMAN
θ value	2.36792 (rank : 105)	NC score	0.006047 (rank : 170)
Query Neighborhood Hits	172	Target Neighborhood Hits	911	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

PKHA5_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.012915 (rank : 128)
Query Neighborhood Hits	172	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

BSN_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.036898 (rank : 73)
Query Neighborhood Hits	172	Target Neighborhood Hits	1537	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CNTRB_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.017897 (rank : 103)
Query Neighborhood Hits	172	Target Neighborhood Hits	1029	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GAK18_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.004319 (rank : 173)
Query Neighborhood Hits	172	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LORI_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.025862 (rank : 88)
Query Neighborhood Hits	172	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P23490	Gene names	LOR, LRN
Domain Architecture	No domain graphic available
Description	Loricrin.

MY18B_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.014659 (rank : 117)
Query Neighborhood Hits	172	Target Neighborhood Hits	1299	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYST3_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.010491 (rank : 149)
Query Neighborhood Hits	172	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NACAM_MOUSE
θ value	3.0926 (rank : 113)	NC score	0.052349 (rank : 60)
Query Neighborhood Hits	172	Target Neighborhood Hits	1866	Shared Neighborhood Hits	66
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PODXL_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.014999 (rank : 115)
Query Neighborhood Hits	172	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PP14A_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.038377 (rank : 69)
Query Neighborhood Hits	172	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

RIMB1_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.012919 (rank : 127)
Query Neighborhood Hits	172	Target Neighborhood Hits	1376	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TAAR1_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.002202 (rank : 179)
Query Neighborhood Hits	172	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

TNIK_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.008449 (rank : 156)
Query Neighborhood Hits	172	Target Neighborhood Hits	1570	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TXLNA_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.015329 (rank : 114)
Query Neighborhood Hits	172	Target Neighborhood Hits	846	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

VCIP1_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.015838 (rank : 110)
Query Neighborhood Hits	172	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

AMOL1_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.015849 (rank : 109)
Query Neighborhood Hits	172	Target Neighborhood Hits	435	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CCD21_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.015392 (rank : 112)
Query Neighborhood Hits	172	Target Neighborhood Hits	1135	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CLOCK_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.012176 (rank : 136)
Query Neighborhood Hits	172	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CSKI2_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.004764 (rank : 171)
Query Neighborhood Hits	172	Target Neighborhood Hits	747	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

E2F3_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.006175 (rank : 169)
Query Neighborhood Hits	172	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

FOXD2_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.001146 (rank : 184)
Query Neighborhood Hits	172	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

LIPS_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.012775 (rank : 130)
Query Neighborhood Hits	172	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MILK1_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.018388 (rank : 101)
Query Neighborhood Hits	172	Target Neighborhood Hits	788	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MY18A_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.010014 (rank : 153)
Query Neighborhood Hits	172	Target Neighborhood Hits	1929	Shared Neighborhood Hits	61
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SYPH_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.014298 (rank : 119)
Query Neighborhood Hits	172	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q62277, Q8BRQ0, Q91WI8	Gene names	Syp
Domain Architecture
Description	Synaptophysin (Major synaptic vesicle protein p38) (BM89 antigen).

ANGL4_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.002901 (rank : 178)
Query Neighborhood Hits	172	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

AR13B_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.006382 (rank : 168)
Query Neighborhood Hits	172	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

BL1S3_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.013546 (rank : 126)
Query Neighborhood Hits	172	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

CD45_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.001808 (rank : 181)
Query Neighborhood Hits	172	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

DLX5_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.001320 (rank : 183)
Query Neighborhood Hits	172	Target Neighborhood Hits	405	Shared Neighborhood Hits	5
SwissProt Accessions	P56178, Q9UPL1	Gene names	DLX5
Domain Architecture
Description	Homeobox protein DLX-5.

FA47A_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.007799 (rank : 159)
Query Neighborhood Hits	172	Target Neighborhood Hits	451	Shared Neighborhood Hits	15
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

KCNQ2_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.029307 (rank : 81)
Query Neighborhood Hits	172	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

MAML1_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.028216 (rank : 83)
Query Neighborhood Hits	172	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

RAD50_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.010098 (rank : 152)
Query Neighborhood Hits	172	Target Neighborhood Hits	1317	Shared Neighborhood Hits	49
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TPR_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.011668 (rank : 139)
Query Neighborhood Hits	172	Target Neighborhood Hits	1921	Shared Neighborhood Hits	69
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TTC28_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.010514 (rank : 148)
Query Neighborhood Hits	172	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTF1_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.010535 (rank : 147)
Query Neighborhood Hits	172	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

TXLNA_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.013925 (rank : 122)
Query Neighborhood Hits	172	Target Neighborhood Hits	982	Shared Neighborhood Hits	47
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

VCIP1_MOUSE
θ value	5.27518 (rank : 144)	NC score	0.014556 (rank : 118)
Query Neighborhood Hits	172	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ALEX_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.023284 (rank : 94)
Query Neighborhood Hits	172	Target Neighborhood Hits	361	Shared Neighborhood Hits	21
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CCHCR_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.010274 (rank : 151)
Query Neighborhood Hits	172	Target Neighborhood Hits	932	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

FES_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.001019 (rank : 185)
Query Neighborhood Hits	172	Target Neighborhood Hits	978	Shared Neighborhood Hits	21
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

KCNQ2_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.027868 (rank : 86)
Query Neighborhood Hits	172	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

NCOA6_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.052931 (rank : 59)
Query Neighborhood Hits	172	Target Neighborhood Hits	1202	Shared Neighborhood Hits	62
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OXR1_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.014784 (rank : 116)
Query Neighborhood Hits	172	Target Neighborhood Hits	282	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

RUFY2_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.010761 (rank : 145)
Query Neighborhood Hits	172	Target Neighborhood Hits	1208	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SRRM1_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.037641 (rank : 71)
Query Neighborhood Hits	172	Target Neighborhood Hits	966	Shared Neighborhood Hits	55
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ULK1_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.006553 (rank : 166)
Query Neighborhood Hits	172	Target Neighborhood Hits	1214	Shared Neighborhood Hits	28
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ATRIP_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.007038 (rank : 163)
Query Neighborhood Hits	172	Target Neighborhood Hits	248	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

BCL6_MOUSE
θ value	8.99809 (rank : 155)	NC score	-0.005538 (rank : 186)
Query Neighborhood Hits	172	Target Neighborhood Hits	913	Shared Neighborhood Hits	10
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

CCD21_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.013724 (rank : 124)
Query Neighborhood Hits	172	Target Neighborhood Hits	1228	Shared Neighborhood Hits	56
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CIC_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.028087 (rank : 84)
Query Neighborhood Hits	172	Target Neighborhood Hits	992	Shared Neighborhood Hits	43
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CMGA_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.010610 (rank : 146)
Query Neighborhood Hits	172	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CO1A2_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.003692 (rank : 175)
Query Neighborhood Hits	172	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

GCC1_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.011225 (rank : 141)
Query Neighborhood Hits	172	Target Neighborhood Hits	887	Shared Neighborhood Hits	45
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGA3_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.010426 (rank : 150)
Query Neighborhood Hits	172	Target Neighborhood Hits	1317	Shared Neighborhood Hits	49
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGB1_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.011172 (rank : 143)
Query Neighborhood Hits	172	Target Neighborhood Hits	2297	Shared Neighborhood Hits	69
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HTRA4_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.031067 (rank : 80)
Query Neighborhood Hits	172	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

KAD6_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.012744 (rank : 131)
Query Neighborhood Hits	172	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

KIFC3_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.009354 (rank : 154)
Query Neighborhood Hits	172	Target Neighborhood Hits	619	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.009002 (rank : 155)
Query Neighborhood Hits	172	Target Neighborhood Hits	571	Shared Neighborhood Hits	37
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

LRC27_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.006608 (rank : 165)
Query Neighborhood Hits	172	Target Neighborhood Hits	710	Shared Neighborhood Hits	29
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

LRSM1_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.008049 (rank : 158)
Query Neighborhood Hits	172	Target Neighborhood Hits	1078	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PRGC1_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.017110 (rank : 106)
Query Neighborhood Hits	172	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

RNC_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.011841 (rank : 138)
Query Neighborhood Hits	172	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

TISB_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.004575 (rank : 172)
Query Neighborhood Hits	172	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

UBIP1_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.003758 (rank : 174)
Query Neighborhood Hits	172	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q811S7, Q3UPR3, Q3US11, Q60786, Q8C514	Gene names	Ubp1, Cp2b, Nf2d9
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9).

CT152_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.081147 (rank : 40)
Query Neighborhood Hits	172	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNK2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.063019 (rank : 47)
Query Neighborhood Hits	172	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.062568 (rank : 48)
Query Neighborhood Hits	172	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.060683 (rank : 50)
Query Neighborhood Hits	172	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.058813 (rank : 51)
Query Neighborhood Hits	172	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.053270 (rank : 58)
Query Neighborhood Hits	172	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.062022 (rank : 49)
Query Neighborhood Hits	172	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.058288 (rank : 52)
Query Neighborhood Hits	172	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.064585 (rank : 46)
Query Neighborhood Hits	172	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.052248 (rank : 61)
Query Neighborhood Hits	172	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.097153 (rank : 39)
Query Neighborhood Hits	172	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

PRRT3_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.050089 (rank : 62)
Query Neighborhood Hits	172	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RPGF4_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.054278 (rank : 55)
Query Neighborhood Hits	172	Target Neighborhood Hits	88	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.056694 (rank : 54)
Query Neighborhood Hits	172	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

Hits sorted by NC score

HCN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	172	Target Neighborhood Hits	172	Shared Neighborhood Hits	172
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN1_HUMAN
NC score	0.990656 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	172	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN3_MOUSE
NC score	0.985210 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	172	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.984889 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	172	Target Neighborhood Hits	99	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.970705 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	172	Target Neighborhood Hits	278	Shared Neighborhood Hits	61
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.969226 (rank : 6)	θ value	0 (rank : 7)
Query Neighborhood Hits	172	Target Neighborhood Hits	303	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.967669 (rank : 7)	θ value	0 (rank : 8)
Query Neighborhood Hits	172	Target Neighborhood Hits	284	Shared Neighborhood Hits	64
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.960621 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	172	Target Neighborhood Hits	369	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGA2_MOUSE
NC score	0.864423 (rank : 9)	θ value	1.28137e-46 (rank : 9)
Query Neighborhood Hits	172	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.857414 (rank : 10)	θ value	8.59492e-43 (rank : 12)
Query Neighborhood Hits	172	Target Neighborhood Hits	84	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.853621 (rank : 11)	θ value	1.32601e-43 (rank : 11)
Query Neighborhood Hits	172	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.852750 (rank : 12)	θ value	2.67181e-44 (rank : 10)
Query Neighborhood Hits	172	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.851416 (rank : 13)	θ value	1.79215e-40 (rank : 13)
Query Neighborhood Hits	172	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
NC score	0.832592 (rank : 14)	θ value	1.16434e-31 (rank : 26)
Query Neighborhood Hits	172	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
NC score	0.825958 (rank : 15)	θ value	2.50655e-34 (rank : 23)
Query Neighborhood Hits	172	Target Neighborhood Hits	222	Shared Neighborhood Hits	55
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
NC score	0.816657 (rank : 16)	θ value	1.85889e-29 (rank : 27)
Query Neighborhood Hits	172	Target Neighborhood Hits	206	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH6_HUMAN
NC score	0.808345 (rank : 17)	θ value	1.98146e-39 (rank : 14)
Query Neighborhood Hits	172	Target Neighborhood Hits	222	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.804862 (rank : 18)	θ value	2.86122e-38 (rank : 18)
Query Neighborhood Hits	172	Target Neighborhood Hits	158	Shared Neighborhood Hits	46
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.804661 (rank : 19)	θ value	2.19075e-38 (rank : 15)
Query Neighborhood Hits	172	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.804142 (rank : 20)	θ value	2.86122e-38 (rank : 19)
Query Neighborhood Hits	172	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.799298 (rank : 21)	θ value	5.96599e-36 (rank : 20)
Query Neighborhood Hits	172	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH5_MOUSE
NC score	0.795665 (rank : 22)	θ value	2.19075e-38 (rank : 17)
Query Neighborhood Hits	172	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.795328 (rank : 23)	θ value	2.19075e-38 (rank : 16)
Query Neighborhood Hits	172	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH4_HUMAN
NC score	0.794930 (rank : 24)	θ value	3.61944e-33 (rank : 24)
Query Neighborhood Hits	172	Target Neighborhood Hits	177	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
NC score	0.789504 (rank : 25)	θ value	5.22648e-32 (rank : 25)
Query Neighborhood Hits	172	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH1_MOUSE
NC score	0.789243 (rank : 26)	θ value	8.61488e-35 (rank : 22)
Query Neighborhood Hits	172	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.789071 (rank : 27)	θ value	8.61488e-35 (rank : 21)
Query Neighborhood Hits	172	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH3_HUMAN
NC score	0.777668 (rank : 28)	θ value	2.42779e-29 (rank : 28)
Query Neighborhood Hits	172	Target Neighborhood Hits	148	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.777258 (rank : 29)	θ value	2.42779e-29 (rank : 29)
Query Neighborhood Hits	172	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
NC score	0.299784 (rank : 30)	θ value	1.87187e-05 (rank : 30)
Query Neighborhood Hits	172	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.269155 (rank : 31)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	172	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.262424 (rank : 32)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	172	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.259359 (rank : 33)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	172	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_MOUSE
NC score	0.244998 (rank : 34)	θ value	0.00390308 (rank : 38)
Query Neighborhood Hits	172	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.241766 (rank : 35)	θ value	0.00390308 (rank : 37)
Query Neighborhood Hits	172	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_MOUSE
NC score	0.236955 (rank : 36)	θ value	0.00228821 (rank : 34)
Query Neighborhood Hits	172	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.231562 (rank : 37)	θ value	0.00228821 (rank : 33)
Query Neighborhood Hits	172	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

CT152_MOUSE
NC score	0.146894 (rank : 38)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	172	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNKH_HUMAN
NC score	0.097153 (rank : 39)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	172	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

CT152_HUMAN
NC score	0.081147 (rank : 40)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	172	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KGP1B_MOUSE
NC score	0.075570 (rank : 41)	θ value	0.00390308 (rank : 39)
Query Neighborhood Hits	172	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.075569 (rank : 42)	θ value	0.00228821 (rank : 36)
Query Neighborhood Hits	172	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.075329 (rank : 43)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	172	Target Neighborhood Hits	901	Shared Neighborhood Hits	52
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP2_MOUSE
NC score	0.075050 (rank : 44)	θ value	5.44631e-05 (rank : 31)
Query Neighborhood Hits	172	Target Neighborhood Hits	1029	Shared Neighborhood Hits	52
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
NC score	0.074911 (rank : 45)	θ value	9.29e-05 (rank : 32)
Query Neighborhood Hits	172	Target Neighborhood Hits	1023	Shared Neighborhood Hits	49
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNKF_HUMAN
NC score	0.064585 (rank : 46)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	172	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.063019 (rank : 47)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	172	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.062568 (rank : 48)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	172	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.062022 (rank : 49)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	172	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_HUMAN
NC score	0.060683 (rank : 50)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	172	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.058813 (rank : 51)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	172	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.058288 (rank : 52)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	172	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

R3HD2_MOUSE
NC score	0.057254 (rank : 53)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	172	Target Neighborhood Hits	397	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RPGF4_MOUSE
NC score	0.056694 (rank : 54)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	172	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RPGF4_HUMAN
NC score	0.054278 (rank : 55)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	172	Target Neighborhood Hits	88	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

SRRM2_MOUSE
NC score	0.053887 (rank : 56)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	172	Target Neighborhood Hits	1470	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BSN_MOUSE
NC score	0.053383 (rank : 57)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	172	Target Neighborhood Hits	2057	Shared Neighborhood Hits	85
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KCNK4_HUMAN
NC score	0.053270 (rank : 58)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	172	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

NCOA6_HUMAN
NC score	0.052931 (rank : 59)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	172	Target Neighborhood Hits	1202	Shared Neighborhood Hits	62
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NACAM_MOUSE
NC score	0.052349 (rank : 60)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	172	Target Neighborhood Hits	1866	Shared Neighborhood Hits	66
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

KCNKG_HUMAN
NC score	0.052248 (rank : 61)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	172	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

PRRT3_HUMAN
NC score	0.050089 (rank : 62)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	172	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

INVO_MOUSE
NC score	0.042889 (rank : 63)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	172	Target Neighborhood Hits	474	Shared Neighborhood Hits	51
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

RGS3_HUMAN
NC score	0.040789 (rank : 64)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	172	Target Neighborhood Hits	1375	Shared Neighborhood Hits	38
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

EMSY_MOUSE
NC score	0.040334 (rank : 65)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	172	Target Neighborhood Hits	294	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

MLL3_HUMAN
NC score	0.040273 (rank : 66)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	172	Target Neighborhood Hits	1644	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DCP1B_HUMAN
NC score	0.039655 (rank : 67)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	172	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

UBP2L_HUMAN
NC score	0.039190 (rank : 68)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	172	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

PP14A_MOUSE
NC score	0.038377 (rank : 69)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	172	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

KCNQ3_MOUSE
NC score	0.038291 (rank : 70)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	172	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

SRRM1_MOUSE
NC score	0.037641 (rank : 71)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	172	Target Neighborhood Hits	966	Shared Neighborhood Hits	55
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

KCNQ3_HUMAN
NC score	0.037576 (rank : 72)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	172	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

BSN_HUMAN
NC score	0.036898 (rank : 73)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	172	Target Neighborhood Hits	1537	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TARA_HUMAN
NC score	0.035743 (rank : 74)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	172	Target Neighborhood Hits	1626	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

INVO_HUMAN
NC score	0.035666 (rank : 75)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	172	Target Neighborhood Hits	636	Shared Neighborhood Hits	46
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

UBP2L_MOUSE
NC score	0.035412 (rank : 76)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	172	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

EMSY_HUMAN
NC score	0.033498 (rank : 77)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	172	Target Neighborhood Hits	296	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

NCOA2_HUMAN
NC score	0.033318 (rank : 78)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	172	Target Neighborhood Hits	281	Shared Neighborhood Hits	23
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

C8AP2_HUMAN
NC score	0.031915 (rank : 79)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	172	Target Neighborhood Hits	548	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

HTRA4_HUMAN
NC score	0.031067 (rank : 80)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	172	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

KCNQ2_HUMAN
NC score	0.029307 (rank : 81)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	172	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

RPTN_HUMAN
NC score	0.028783 (rank : 82)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	172	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

MAML1_MOUSE
NC score	0.028216 (rank : 83)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	172	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CIC_HUMAN
NC score	0.028087 (rank : 84)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	172	Target Neighborhood Hits	992	Shared Neighborhood Hits	43
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

NFAT5_HUMAN
NC score	0.028034 (rank : 85)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	172	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

KCNQ2_MOUSE
NC score	0.027868 (rank : 86)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	172	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

ACINU_HUMAN
NC score	0.026590 (rank : 87)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	172	Target Neighborhood Hits	828	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LORI_HUMAN
NC score	0.025862 (rank : 88)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	172	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P23490	Gene names	LOR, LRN
Domain Architecture	No domain graphic available
Description	Loricrin.

HAP1_HUMAN
NC score	0.025062 (rank : 89)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	172	Target Neighborhood Hits	606	Shared Neighborhood Hits	42
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HAP1_MOUSE
NC score	0.024602 (rank : 90)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	172	Target Neighborhood Hits	388	Shared Neighborhood Hits	25
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

NFAT5_MOUSE
NC score	0.023679 (rank : 91)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	172	Target Neighborhood Hits	162	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

HGS_MOUSE
NC score	0.023320 (rank : 92)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	172	Target Neighborhood Hits	589	Shared Neighborhood Hits	33
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

SIA7A_HUMAN
NC score	0.023298 (rank : 93)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	172	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

ALEX_HUMAN
NC score	0.023284 (rank : 94)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	172	Target Neighborhood Hits	361	Shared Neighborhood Hits	21
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

HGS_HUMAN
NC score	0.022646 (rank : 95)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	172	Target Neighborhood Hits	517	Shared Neighborhood Hits	32
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

UBP10_MOUSE
NC score	0.020935 (rank : 96)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	172	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

RPTN_MOUSE
NC score	0.020798 (rank : 97)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	172	Target Neighborhood Hits	650	Shared Neighborhood Hits	35
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

ADDB_MOUSE
NC score	0.020584 (rank : 98)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	172	Target Neighborhood Hits	574	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

SYPH_HUMAN
NC score	0.020445 (rank : 99)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	172	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P08247, Q6P2F7	Gene names	SYP
Domain Architecture
Description	Synaptophysin (Major synaptic vesicle protein p38).

KCNN3_MOUSE
NC score	0.020338 (rank : 100)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	172	Target Neighborhood Hits	171	Shared Neighborhood Hits	28
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

MILK1_MOUSE
NC score	0.018388 (rank : 101)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	172	Target Neighborhood Hits	788	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RING1_HUMAN
NC score	0.018022 (rank : 102)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	172	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

CNTRB_MOUSE
NC score	0.017897 (rank : 103)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	172	Target Neighborhood Hits	1029	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

AMOL1_MOUSE
NC score	0.017730 (rank : 104)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	172	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

RGNEF_MOUSE
NC score	0.017271 (rank : 105)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	172	Target Neighborhood Hits	641	Shared Neighborhood Hits	44
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

PRGC1_MOUSE
NC score	0.017110 (rank : 106)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	172	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

KCNS3_HUMAN
NC score	0.016998 (rank : 107)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	172	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

CCR3_MOUSE
NC score	0.016075 (rank : 108)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	172	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

AMOL1_HUMAN
NC score	0.015849 (rank : 109)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	172	Target Neighborhood Hits	435	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

VCIP1_HUMAN
NC score	0.015838 (rank : 110)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	172	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ITSN1_HUMAN
NC score	0.015637 (rank : 111)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	172	Target Neighborhood Hits	1757	Shared Neighborhood Hits	65
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

CCD21_MOUSE
NC score	0.015392 (rank : 112)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	172	Target Neighborhood Hits	1135	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

AHTF1_HUMAN
NC score	0.015361 (rank : 113)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	172	Target Neighborhood Hits	286	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

TXLNA_MOUSE
NC score	0.015329 (rank : 114)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	172	Target Neighborhood Hits	846	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

PODXL_HUMAN
NC score	0.014999 (rank : 115)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	172	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

OXR1_HUMAN
NC score	0.014784 (rank : 116)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	172	Target Neighborhood Hits	282	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

MY18B_HUMAN
NC score	0.014659 (rank : 117)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	172	Target Neighborhood Hits	1299	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

VCIP1_MOUSE
NC score	0.014556 (rank : 118)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	172	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

SYPH_MOUSE
NC score	0.014298 (rank : 119)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	172	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q62277, Q8BRQ0, Q91WI8	Gene names	Syp
Domain Architecture
Description	Synaptophysin (Major synaptic vesicle protein p38) (BM89 antigen).

NPAS2_HUMAN
NC score	0.014261 (rank : 120)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	172	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

ITSN1_MOUSE
NC score	0.014184 (rank : 121)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	172	Target Neighborhood Hits	1669	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TXLNA_HUMAN
NC score	0.013925 (rank : 122)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	172	Target Neighborhood Hits	982	Shared Neighborhood Hits	47
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

LARP4_HUMAN
NC score	0.013828 (rank : 123)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	172	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

CCD21_HUMAN
NC score	0.013724 (rank : 124)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	172	Target Neighborhood Hits	1228	Shared Neighborhood Hits	56
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

AKAP9_HUMAN
NC score	0.013602 (rank : 125)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	172	Target Neighborhood Hits	1710	Shared Neighborhood Hits	61
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BL1S3_MOUSE
NC score	0.013546 (rank : 126)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	172	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

RIMB1_MOUSE
NC score	0.012919 (rank : 127)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	172	Target Neighborhood Hits	1376	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PKHA5_HUMAN
NC score	0.012915 (rank : 128)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	172	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

MRCKB_HUMAN
NC score	0.012797 (rank : 129)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	172	Target Neighborhood Hits	2239	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

LIPS_HUMAN
NC score	0.012775 (rank : 130)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	172	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

KAD6_HUMAN
NC score	0.012744 (rank : 131)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	172	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

STK10_MOUSE
NC score	0.012544 (rank : 132)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	172	Target Neighborhood Hits	2132	Shared Neighborhood Hits	68
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

KI21A_MOUSE
NC score	0.012236 (rank : 133)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	172	Target Neighborhood Hits	1317	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

ASPP2_HUMAN
NC score	0.012226 (rank : 134)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	172	Target Neighborhood Hits	1156	Shared Neighborhood Hits	59
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MRCKB_MOUSE
NC score	0.012196 (rank : 135)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	172	Target Neighborhood Hits	2180	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CLOCK_MOUSE
NC score	0.012176 (rank : 136)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	172	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

HDAC4_HUMAN
NC score	0.012048 (rank : 137)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	172	Target Neighborhood Hits	390	Shared Neighborhood Hits	34
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

RNC_HUMAN
NC score	0.011841 (rank : 138)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	172	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

TPR_HUMAN
NC score	0.011668 (rank : 139)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	172	Target Neighborhood Hits	1921	Shared Neighborhood Hits	69
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

STK10_HUMAN
NC score	0.011580 (rank : 140)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	172	Target Neighborhood Hits	1921	Shared Neighborhood Hits	60
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

GCC1_HUMAN
NC score	0.011225 (rank : 141)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	172	Target Neighborhood Hits	887	Shared Neighborhood Hits	45
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

KI21A_HUMAN
NC score	0.011210 (rank : 142)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	172	Target Neighborhood Hits	1543	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

GOGB1_HUMAN
NC score	0.011172 (rank : 143)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	172	Target Neighborhood Hits	2297	Shared Neighborhood Hits	69
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

DESP_HUMAN
NC score	0.010790 (rank : 144)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	172	Target Neighborhood Hits	1470	Shared Neighborhood Hits	54
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

RUFY2_HUMAN
NC score	0.010761 (rank : 145)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	172	Target Neighborhood Hits	1208	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CMGA_HUMAN
NC score	0.010610 (rank : 146)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	172	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

TTF1_MOUSE
NC score	0.010535 (rank : 147)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	172	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

TTC28_HUMAN
NC score	0.010514 (rank : 148)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	172	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

MYST3_HUMAN
NC score	0.010491 (rank : 149)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	172	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

GOGA3_HUMAN
NC score	0.010426 (rank : 150)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	172	Target Neighborhood Hits	1317	Shared Neighborhood Hits	49
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

CCHCR_MOUSE
NC score	0.010274 (rank : 151)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	172	Target Neighborhood Hits	932	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

RAD50_HUMAN
NC score	0.010098 (rank : 152)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	172	Target Neighborhood Hits	1317	Shared Neighborhood Hits	49
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

MY18A_HUMAN
NC score	0.010014 (rank : 153)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	172	Target Neighborhood Hits	1929	Shared Neighborhood Hits	61
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

KIFC3_HUMAN
NC score	0.009354 (rank : 154)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	172	Target Neighborhood Hits	619	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
NC score	0.009002 (rank : 155)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	172	Target Neighborhood Hits	571	Shared Neighborhood Hits	37
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

TNIK_HUMAN
NC score	0.008449 (rank : 156)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	172	Target Neighborhood Hits	1570	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

OSB10_HUMAN
NC score	0.008059 (rank : 157)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	172	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

LRSM1_HUMAN
NC score	0.008049 (rank : 158)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	172	Target Neighborhood Hits	1078	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

FA47A_HUMAN
NC score	0.007799 (rank : 159)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	172	Target Neighborhood Hits	451	Shared Neighborhood Hits	15
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

EVX2_MOUSE
NC score	0.007511 (rank : 160)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	172	Target Neighborhood Hits	327	Shared Neighborhood Hits	5
SwissProt Accessions	P49749	Gene names	Evx2, Evx-2
Domain Architecture
Description	Homeobox even-skipped homolog protein 2 (EVX-2).

EVX2_HUMAN
NC score	0.007477 (rank : 161)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	172	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q03828	Gene names	EVX2
Domain Architecture
Description	Homeobox even-skipped homolog protein 2 (EVX-2).

ANK2_HUMAN
NC score	0.007214 (rank : 162)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	172	Target Neighborhood Hits	1615	Shared Neighborhood Hits	49
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ATRIP_MOUSE
NC score	0.007038 (rank : 163)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	172	Target Neighborhood Hits	248	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

CSKI2_MOUSE
NC score	0.006974 (rank : 164)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	172	Target Neighborhood Hits	812	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

LRC27_HUMAN
NC score	0.006608 (rank : 165)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	172	Target Neighborhood Hits	710	Shared Neighborhood Hits	29
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

ULK1_MOUSE
NC score	0.006553 (rank : 166)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	172	Target Neighborhood Hits	1214	Shared Neighborhood Hits	28
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ELF1_HUMAN
NC score	0.006437 (rank : 167)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	172	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

AR13B_HUMAN
NC score	0.006382 (rank : 168)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	172	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

E2F3_HUMAN
NC score	0.006175 (rank : 169)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	172	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

MYO5B_HUMAN
NC score	0.006047 (rank : 170)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	172	Target Neighborhood Hits	911	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

CSKI2_HUMAN
NC score	0.004764 (rank : 171)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	172	Target Neighborhood Hits	747	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TISB_HUMAN
NC score	0.004575 (rank : 172)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	172	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

GAK18_HUMAN
NC score	0.004319 (rank : 173)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	172	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

UBIP1_MOUSE
NC score	0.003758 (rank : 174)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	172	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q811S7, Q3UPR3, Q3US11, Q60786, Q8C514	Gene names	Ubp1, Cp2b, Nf2d9
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9).

CO1A2_MOUSE
NC score	0.003692 (rank : 175)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	172	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

NKX32_HUMAN
NC score	0.003652 (rank : 176)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	172	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	P78367	Gene names	BAPX1, NKX3B
Domain Architecture
Description	Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1).

FBLN2_HUMAN
NC score	0.003326 (rank : 177)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	172	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ANGL4_MOUSE
NC score	0.002901 (rank : 178)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	172	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

TAAR1_HUMAN
NC score	0.002202 (rank : 179)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	172	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

LAP2_HUMAN
NC score	0.001886 (rank : 180)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	172	Target Neighborhood Hits	499	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CD45_HUMAN
NC score	0.001808 (rank : 181)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	172	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

ZEP1_MOUSE
NC score	0.001801 (rank : 182)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	172	Target Neighborhood Hits	1063	Shared Neighborhood Hits	20
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

DLX5_HUMAN
NC score	0.001320 (rank : 183)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	172	Target Neighborhood Hits	405	Shared Neighborhood Hits	5
SwissProt Accessions	P56178, Q9UPL1	Gene names	DLX5
Domain Architecture
Description	Homeobox protein DLX-5.

FOXD2_HUMAN
NC score	0.001146 (rank : 184)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	172	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

FES_HUMAN
NC score	0.001019 (rank : 185)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	172	Target Neighborhood Hits	978	Shared Neighborhood Hits	21
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

BCL6_MOUSE
NC score	-0.005538 (rank : 186)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	172	Target Neighborhood Hits	913	Shared Neighborhood Hits	10
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.