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Network neighborhood for query Sequence : CSKI2_MOUSE

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CSKI2_MOUSE
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CSKI1_HUMAN
θ value	0 (rank : 1)	NC score	0.942440 (rank : 3)
Query Neighborhood Hits	812	Target Neighborhood Hits	997	Shared Neighborhood Hits	520
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	0 (rank : 2)	NC score	0.941009 (rank : 4)
Query Neighborhood Hits	812	Target Neighborhood Hits	1031	Shared Neighborhood Hits	529
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	0 (rank : 3)	NC score	0.976540 (rank : 2)
Query Neighborhood Hits	812	Target Neighborhood Hits	747	Shared Neighborhood Hits	539
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	812	Target Neighborhood Hits	812	Shared Neighborhood Hits	812
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_HUMAN
θ value	1.01294e-51 (rank : 5)	NC score	0.894832 (rank : 5)
Query Neighborhood Hits	812	Target Neighborhood Hits	438	Shared Neighborhood Hits	348
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	1.04822e-48 (rank : 6)	NC score	0.889573 (rank : 6)
Query Neighborhood Hits	812	Target Neighborhood Hits	453	Shared Neighborhood Hits	348
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

RIPK4_HUMAN
θ value	1.98606e-31 (rank : 7)	NC score	0.583064 (rank : 201)
Query Neighborhood Hits	812	Target Neighborhood Hits	1094	Shared Neighborhood Hits	342
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANK1_HUMAN
θ value	7.80994e-28 (rank : 8)	NC score	0.853744 (rank : 26)
Query Neighborhood Hits	812	Target Neighborhood Hits	416	Shared Neighborhood Hits	305
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	7.80994e-28 (rank : 9)	NC score	0.852819 (rank : 27)
Query Neighborhood Hits	812	Target Neighborhood Hits	430	Shared Neighborhood Hits	302
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK3_HUMAN
θ value	1.33217e-27 (rank : 10)	NC score	0.843877 (rank : 37)
Query Neighborhood Hits	812	Target Neighborhood Hits	853	Shared Neighborhood Hits	351
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANK2_HUMAN
θ value	2.51237e-26 (rank : 11)	NC score	0.808236 (rank : 87)
Query Neighborhood Hits	812	Target Neighborhood Hits	1615	Shared Neighborhood Hits	484
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKK1_HUMAN
θ value	2.12685e-25 (rank : 12)	NC score	0.583014 (rank : 202)
Query Neighborhood Hits	812	Target Neighborhood Hits	1075	Shared Neighborhood Hits	335
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR28_MOUSE
θ value	2.12685e-25 (rank : 13)	NC score	0.856395 (rank : 23)
Query Neighborhood Hits	812	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR44_HUMAN
θ value	5.23862e-24 (rank : 14)	NC score	0.856509 (rank : 22)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANKK1_MOUSE
θ value	1.5242e-23 (rank : 15)	NC score	0.568829 (rank : 207)
Query Neighborhood Hits	812	Target Neighborhood Hits	1072	Shared Neighborhood Hits	333
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR28_HUMAN
θ value	1.99067e-23 (rank : 16)	NC score	0.854546 (rank : 25)
Query Neighborhood Hits	812	Target Neighborhood Hits	314	Shared Neighborhood Hits	292
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_HUMAN
θ value	3.39556e-23 (rank : 17)	NC score	0.849338 (rank : 30)
Query Neighborhood Hits	812	Target Neighborhood Hits	322	Shared Neighborhood Hits	296
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	4.43474e-23 (rank : 18)	NC score	0.849629 (rank : 29)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNKS2_HUMAN
θ value	4.43474e-23 (rank : 19)	NC score	0.856039 (rank : 24)
Query Neighborhood Hits	812	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR50_HUMAN
θ value	5.79196e-23 (rank : 20)	NC score	0.865806 (rank : 13)
Query Neighborhood Hits	812	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
θ value	1.29031e-22 (rank : 21)	NC score	0.864378 (rank : 14)
Query Neighborhood Hits	812	Target Neighborhood Hits	477	Shared Neighborhood Hits	366
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

DAPK1_HUMAN
θ value	6.40375e-22 (rank : 22)	NC score	0.405420 (rank : 258)
Query Neighborhood Hits	812	Target Neighborhood Hits	1130	Shared Neighborhood Hits	335
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TNI3K_HUMAN
θ value	6.40375e-22 (rank : 23)	NC score	0.472540 (rank : 240)
Query Neighborhood Hits	812	Target Neighborhood Hits	1084	Shared Neighborhood Hits	341
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKR6_HUMAN
θ value	1.86321e-21 (rank : 24)	NC score	0.870977 (rank : 10)
Query Neighborhood Hits	812	Target Neighborhood Hits	439	Shared Neighborhood Hits	304
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

MYPT2_HUMAN
θ value	1.86321e-21 (rank : 25)	NC score	0.821714 (rank : 69)
Query Neighborhood Hits	812	Target Neighborhood Hits	707	Shared Neighborhood Hits	309
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

DAPK1_MOUSE
θ value	2.43343e-21 (rank : 26)	NC score	0.413103 (rank : 255)
Query Neighborhood Hits	812	Target Neighborhood Hits	1138	Shared Neighborhood Hits	341
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ANR42_HUMAN
θ value	3.17815e-21 (rank : 27)	NC score	0.867747 (rank : 12)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR29_HUMAN
θ value	4.15078e-21 (rank : 28)	NC score	0.877713 (rank : 7)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

TNI3K_MOUSE
θ value	7.0802e-21 (rank : 29)	NC score	0.467012 (rank : 241)
Query Neighborhood Hits	812	Target Neighborhood Hits	1079	Shared Neighborhood Hits	340
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

MIB1_HUMAN
θ value	3.51386e-20 (rank : 30)	NC score	0.821836 (rank : 68)
Query Neighborhood Hits	812	Target Neighborhood Hits	470	Shared Neighborhood Hits	302
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	3.51386e-20 (rank : 31)	NC score	0.821515 (rank : 71)
Query Neighborhood Hits	812	Target Neighborhood Hits	471	Shared Neighborhood Hits	301
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RAI14_HUMAN
θ value	3.51386e-20 (rank : 32)	NC score	0.636733 (rank : 186)
Query Neighborhood Hits	812	Target Neighborhood Hits	1367	Shared Neighborhood Hits	353
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR42_MOUSE
θ value	5.99374e-20 (rank : 33)	NC score	0.863526 (rank : 15)
Query Neighborhood Hits	812	Target Neighborhood Hits	334	Shared Neighborhood Hits	279
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB10_MOUSE
θ value	5.99374e-20 (rank : 34)	NC score	0.860865 (rank : 18)
Query Neighborhood Hits	812	Target Neighborhood Hits	301	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CTTB2_HUMAN
θ value	1.74391e-19 (rank : 35)	NC score	0.747256 (rank : 140)
Query Neighborhood Hits	812	Target Neighborhood Hits	1061	Shared Neighborhood Hits	348
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

RAI14_MOUSE
θ value	5.07402e-19 (rank : 36)	NC score	0.602781 (rank : 194)
Query Neighborhood Hits	812	Target Neighborhood Hits	1505	Shared Neighborhood Hits	353
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ASB2_HUMAN
θ value	1.92812e-18 (rank : 37)	NC score	0.843550 (rank : 39)
Query Neighborhood Hits	812	Target Neighborhood Hits	309	Shared Neighborhood Hits	288
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_HUMAN
θ value	1.92812e-18 (rank : 38)	NC score	0.859659 (rank : 21)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

PSD10_HUMAN
θ value	1.92812e-18 (rank : 39)	NC score	0.873951 (rank : 8)
Query Neighborhood Hits	812	Target Neighborhood Hits	301	Shared Neighborhood Hits	287
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ASB7_HUMAN
θ value	2.5182e-18 (rank : 40)	NC score	0.863088 (rank : 16)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

INVS_HUMAN
θ value	2.5182e-18 (rank : 41)	NC score	0.852322 (rank : 28)
Query Neighborhood Hits	812	Target Neighborhood Hits	455	Shared Neighborhood Hits	322
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB7_MOUSE
θ value	3.28887e-18 (rank : 42)	NC score	0.863063 (rank : 17)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

INVS_MOUSE
θ value	4.29542e-18 (rank : 43)	NC score	0.848387 (rank : 32)
Query Neighborhood Hits	812	Target Neighborhood Hits	609	Shared Neighborhood Hits	360
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB3_MOUSE
θ value	5.60996e-18 (rank : 44)	NC score	0.860793 (rank : 19)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	294
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB10_HUMAN
θ value	7.32683e-18 (rank : 45)	NC score	0.859928 (rank : 20)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

MIB2_HUMAN
θ value	9.56915e-18 (rank : 46)	NC score	0.812196 (rank : 82)
Query Neighborhood Hits	812	Target Neighborhood Hits	438	Shared Neighborhood Hits	294
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

PSD10_MOUSE
θ value	9.56915e-18 (rank : 47)	NC score	0.872215 (rank : 9)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MYPT1_HUMAN
θ value	1.63225e-17 (rank : 48)	NC score	0.815461 (rank : 76)
Query Neighborhood Hits	812	Target Neighborhood Hits	723	Shared Neighborhood Hits	314
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	2.7842e-17 (rank : 49)	NC score	0.835452 (rank : 45)
Query Neighborhood Hits	812	Target Neighborhood Hits	539	Shared Neighborhood Hits	309
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ZDH17_HUMAN
θ value	3.63628e-17 (rank : 50)	NC score	0.754304 (rank : 134)
Query Neighborhood Hits	812	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ASB5_HUMAN
θ value	4.74913e-17 (rank : 51)	NC score	0.819475 (rank : 73)
Query Neighborhood Hits	812	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ZDH17_MOUSE
θ value	6.20254e-17 (rank : 52)	NC score	0.749962 (rank : 137)
Query Neighborhood Hits	812	Target Neighborhood Hits	328	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ASB5_MOUSE
θ value	8.10077e-17 (rank : 53)	NC score	0.817323 (rank : 74)
Query Neighborhood Hits	812	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

MIB2_MOUSE
θ value	8.10077e-17 (rank : 54)	NC score	0.812612 (rank : 80)
Query Neighborhood Hits	812	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PP16A_MOUSE
θ value	8.10077e-17 (rank : 55)	NC score	0.829339 (rank : 57)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	284
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANR35_HUMAN
θ value	3.07829e-16 (rank : 56)	NC score	0.775597 (rank : 123)
Query Neighborhood Hits	812	Target Neighborhood Hits	784	Shared Neighborhood Hits	307
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

EHMT1_HUMAN
θ value	3.07829e-16 (rank : 57)	NC score	0.795875 (rank : 104)
Query Neighborhood Hits	812	Target Neighborhood Hits	417	Shared Neighborhood Hits	308
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANKR2_HUMAN
θ value	5.25075e-16 (rank : 58)	NC score	0.843449 (rank : 40)
Query Neighborhood Hits	812	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB9_MOUSE
θ value	6.85773e-16 (rank : 59)	NC score	0.813369 (rank : 79)
Query Neighborhood Hits	812	Target Neighborhood Hits	257	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

TRPA1_HUMAN
θ value	6.85773e-16 (rank : 60)	NC score	0.833366 (rank : 51)
Query Neighborhood Hits	812	Target Neighborhood Hits	339	Shared Neighborhood Hits	293
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ASB13_MOUSE
θ value	8.95645e-16 (rank : 61)	NC score	0.848355 (rank : 33)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB2_MOUSE
θ value	8.95645e-16 (rank : 62)	NC score	0.838681 (rank : 43)
Query Neighborhood Hits	812	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

PP16B_HUMAN
θ value	8.95645e-16 (rank : 63)	NC score	0.822887 (rank : 65)
Query Neighborhood Hits	812	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ANKR2_MOUSE
θ value	1.16975e-15 (rank : 64)	NC score	0.845242 (rank : 36)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ASB13_HUMAN
θ value	1.52774e-15 (rank : 65)	NC score	0.848182 (rank : 35)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

NOTC4_HUMAN
θ value	3.40345e-15 (rank : 66)	NC score	0.445781 (rank : 248)
Query Neighborhood Hits	812	Target Neighborhood Hits	905	Shared Neighborhood Hits	309
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPA1_MOUSE
θ value	3.40345e-15 (rank : 67)	NC score	0.833436 (rank : 50)
Query Neighborhood Hits	812	Target Neighborhood Hits	343	Shared Neighborhood Hits	294
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

NOTC4_MOUSE
θ value	9.90251e-15 (rank : 68)	NC score	0.450790 (rank : 246)
Query Neighborhood Hits	812	Target Neighborhood Hits	872	Shared Neighborhood Hits	304
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PP16B_MOUSE
θ value	9.90251e-15 (rank : 69)	NC score	0.820695 (rank : 72)
Query Neighborhood Hits	812	Target Neighborhood Hits	302	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR23_MOUSE
θ value	1.29331e-14 (rank : 70)	NC score	0.843607 (rank : 38)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB9_HUMAN
θ value	1.29331e-14 (rank : 71)	NC score	0.821984 (rank : 67)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	256
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANKS6_HUMAN
θ value	1.68911e-14 (rank : 72)	NC score	0.833830 (rank : 47)
Query Neighborhood Hits	812	Target Neighborhood Hits	411	Shared Neighborhood Hits	330
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR12_HUMAN
θ value	1.68911e-14 (rank : 73)	NC score	0.712604 (rank : 155)
Query Neighborhood Hits	812	Target Neighborhood Hits	1081	Shared Neighborhood Hits	315
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

PA2G6_MOUSE
θ value	1.68911e-14 (rank : 74)	NC score	0.823894 (rank : 62)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PP16A_HUMAN
θ value	1.68911e-14 (rank : 75)	NC score	0.823028 (rank : 64)
Query Neighborhood Hits	812	Target Neighborhood Hits	340	Shared Neighborhood Hits	293
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR16_HUMAN
θ value	2.20605e-14 (rank : 76)	NC score	0.868322 (rank : 11)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR11_HUMAN
θ value	3.76295e-14 (rank : 77)	NC score	0.753025 (rank : 135)
Query Neighborhood Hits	812	Target Neighborhood Hits	1289	Shared Neighborhood Hits	404
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

EHMT2_HUMAN
θ value	4.91457e-14 (rank : 78)	NC score	0.781479 (rank : 116)
Query Neighborhood Hits	812	Target Neighborhood Hits	498	Shared Neighborhood Hits	311
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ZDH13_MOUSE
θ value	4.91457e-14 (rank : 79)	NC score	0.740435 (rank : 145)
Query Neighborhood Hits	812	Target Neighborhood Hits	329	Shared Neighborhood Hits	279
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

MUC1_HUMAN
θ value	6.41864e-14 (rank : 80)	NC score	0.132565 (rank : 305)
Query Neighborhood Hits	812	Target Neighborhood Hits	975	Shared Neighborhood Hits	210
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ANKS6_MOUSE
θ value	1.09485e-13 (rank : 81)	NC score	0.833672 (rank : 48)
Query Neighborhood Hits	812	Target Neighborhood Hits	435	Shared Neighborhood Hits	333
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

FANK1_HUMAN
θ value	2.43908e-13 (rank : 82)	NC score	0.849233 (rank : 31)
Query Neighborhood Hits	812	Target Neighborhood Hits	326	Shared Neighborhood Hits	292
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANFY1_MOUSE
θ value	3.18553e-13 (rank : 83)	NC score	0.748036 (rank : 139)
Query Neighborhood Hits	812	Target Neighborhood Hits	480	Shared Neighborhood Hits	291
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB15_HUMAN
θ value	4.16044e-13 (rank : 84)	NC score	0.816067 (rank : 75)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

EHMT2_MOUSE
θ value	4.16044e-13 (rank : 85)	NC score	0.775782 (rank : 121)
Query Neighborhood Hits	812	Target Neighborhood Hits	750	Shared Neighborhood Hits	392
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB11_HUMAN
θ value	5.43371e-13 (rank : 86)	NC score	0.814971 (rank : 77)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

GABP2_HUMAN
θ value	5.43371e-13 (rank : 87)	NC score	0.829943 (rank : 55)
Query Neighborhood Hits	812	Target Neighborhood Hits	454	Shared Neighborhood Hits	296
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

RN5A_MOUSE
θ value	5.43371e-13 (rank : 88)	NC score	0.744898 (rank : 142)
Query Neighborhood Hits	812	Target Neighborhood Hits	899	Shared Neighborhood Hits	326
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANFY1_HUMAN
θ value	7.09661e-13 (rank : 89)	NC score	0.746628 (rank : 141)
Query Neighborhood Hits	812	Target Neighborhood Hits	480	Shared Neighborhood Hits	285
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB11_MOUSE
θ value	7.09661e-13 (rank : 90)	NC score	0.812362 (rank : 81)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ZDH13_HUMAN
θ value	7.09661e-13 (rank : 91)	NC score	0.738332 (rank : 148)
Query Neighborhood Hits	812	Target Neighborhood Hits	322	Shared Neighborhood Hits	275
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

GABP3_MOUSE
θ value	9.26847e-13 (rank : 92)	NC score	0.830540 (rank : 54)
Query Neighborhood Hits	812	Target Neighborhood Hits	330	Shared Neighborhood Hits	280
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANR23_HUMAN
θ value	1.2105e-12 (rank : 93)	NC score	0.837970 (rank : 44)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	283
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

GABP2_MOUSE
θ value	1.58096e-12 (rank : 94)	NC score	0.832170 (rank : 52)
Query Neighborhood Hits	812	Target Neighborhood Hits	429	Shared Neighborhood Hits	297
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ILK_MOUSE
θ value	1.58096e-12 (rank : 95)	NC score	0.538152 (rank : 218)
Query Neighborhood Hits	812	Target Neighborhood Hits	858	Shared Neighborhood Hits	318
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ASB15_MOUSE
θ value	2.69671e-12 (rank : 96)	NC score	0.808020 (rank : 88)
Query Neighborhood Hits	812	Target Neighborhood Hits	292	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ILK1_HUMAN
θ value	2.69671e-12 (rank : 97)	NC score	0.539253 (rank : 217)
Query Neighborhood Hits	812	Target Neighborhood Hits	857	Shared Neighborhood Hits	318
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	2.69671e-12 (rank : 98)	NC score	0.556484 (rank : 215)
Query Neighborhood Hits	812	Target Neighborhood Hits	848	Shared Neighborhood Hits	318
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

SHAN1_HUMAN
θ value	6.00763e-12 (rank : 99)	NC score	0.740120 (rank : 146)
Query Neighborhood Hits	812	Target Neighborhood Hits	1041	Shared Neighborhood Hits	471
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKR1_HUMAN
θ value	7.84624e-12 (rank : 100)	NC score	0.834047 (rank : 46)
Query Neighborhood Hits	812	Target Neighborhood Hits	308	Shared Neighborhood Hits	278
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	7.84624e-12 (rank : 101)	NC score	0.833519 (rank : 49)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	285
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

FANK1_MOUSE
θ value	1.02475e-11 (rank : 102)	NC score	0.848237 (rank : 34)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	291
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

BCL3_HUMAN
θ value	1.74796e-11 (rank : 103)	NC score	0.825312 (rank : 60)
Query Neighborhood Hits	812	Target Neighborhood Hits	324	Shared Neighborhood Hits	290
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANR39_MOUSE
θ value	2.28291e-11 (rank : 104)	NC score	0.842940 (rank : 42)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB4_HUMAN
θ value	2.28291e-11 (rank : 105)	NC score	0.799645 (rank : 98)
Query Neighborhood Hits	812	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

BCL3_MOUSE
θ value	2.28291e-11 (rank : 106)	NC score	0.822083 (rank : 66)
Query Neighborhood Hits	812	Target Neighborhood Hits	388	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB16_MOUSE
θ value	2.98157e-11 (rank : 107)	NC score	0.821580 (rank : 70)
Query Neighborhood Hits	812	Target Neighborhood Hits	306	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB4_MOUSE
θ value	3.89403e-11 (rank : 108)	NC score	0.798174 (rank : 101)
Query Neighborhood Hits	812	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

OSBL1_HUMAN
θ value	3.89403e-11 (rank : 109)	NC score	0.661343 (rank : 176)
Query Neighborhood Hits	812	Target Neighborhood Hits	368	Shared Neighborhood Hits	283
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR39_HUMAN
θ value	6.64225e-11 (rank : 110)	NC score	0.843019 (rank : 41)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	277
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB14_MOUSE
θ value	8.67504e-11 (rank : 111)	NC score	0.805461 (rank : 90)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

RN5A_HUMAN
θ value	1.133e-10 (rank : 112)	NC score	0.787489 (rank : 110)
Query Neighborhood Hits	812	Target Neighborhood Hits	608	Shared Neighborhood Hits	303
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CDN2C_HUMAN
θ value	1.47974e-10 (rank : 113)	NC score	0.829457 (rank : 56)
Query Neighborhood Hits	812	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

UACA_HUMAN
θ value	1.47974e-10 (rank : 114)	NC score	0.490100 (rank : 234)
Query Neighborhood Hits	812	Target Neighborhood Hits	1622	Shared Neighborhood Hits	335
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANKS3_HUMAN
θ value	3.29651e-10 (rank : 115)	NC score	0.811243 (rank : 84)
Query Neighborhood Hits	812	Target Neighborhood Hits	355	Shared Neighborhood Hits	284
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

BARD1_HUMAN
θ value	3.29651e-10 (rank : 116)	NC score	0.786921 (rank : 112)
Query Neighborhood Hits	812	Target Neighborhood Hits	427	Shared Neighborhood Hits	290
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBE_HUMAN
θ value	3.29651e-10 (rank : 117)	NC score	0.770802 (rank : 126)
Query Neighborhood Hits	812	Target Neighborhood Hits	288	Shared Neighborhood Hits	270
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBE_MOUSE
θ value	3.29651e-10 (rank : 118)	NC score	0.788567 (rank : 109)
Query Neighborhood Hits	812	Target Neighborhood Hits	308	Shared Neighborhood Hits	277
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

BARD1_MOUSE
θ value	4.30538e-10 (rank : 119)	NC score	0.785759 (rank : 115)
Query Neighborhood Hits	812	Target Neighborhood Hits	411	Shared Neighborhood Hits	285
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CDN2C_MOUSE
θ value	4.30538e-10 (rank : 120)	NC score	0.828689 (rank : 58)
Query Neighborhood Hits	812	Target Neighborhood Hits	270	Shared Neighborhood Hits	268
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR19_HUMAN
θ value	5.62301e-10 (rank : 121)	NC score	0.744299 (rank : 143)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	268
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

IKBA_HUMAN
θ value	5.62301e-10 (rank : 122)	NC score	0.800565 (rank : 97)
Query Neighborhood Hits	812	Target Neighborhood Hits	280	Shared Neighborhood Hits	270
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANKS3_MOUSE
θ value	7.34386e-10 (rank : 123)	NC score	0.813577 (rank : 78)
Query Neighborhood Hits	812	Target Neighborhood Hits	355	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

KRIT1_MOUSE
θ value	7.34386e-10 (rank : 124)	NC score	0.700385 (rank : 161)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	228
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MPP8_HUMAN
θ value	7.34386e-10 (rank : 125)	NC score	0.653693 (rank : 178)
Query Neighborhood Hits	812	Target Neighborhood Hits	948	Shared Neighborhood Hits	282
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR49_MOUSE
θ value	9.59137e-10 (rank : 126)	NC score	0.830554 (rank : 53)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

IKBA_MOUSE
θ value	1.25267e-09 (rank : 127)	NC score	0.789467 (rank : 108)
Query Neighborhood Hits	812	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR18_HUMAN
θ value	1.63604e-09 (rank : 128)	NC score	0.595762 (rank : 196)
Query Neighborhood Hits	812	Target Neighborhood Hits	1106	Shared Neighborhood Hits	303
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR10_HUMAN
θ value	2.13673e-09 (rank : 129)	NC score	0.801571 (rank : 94)
Query Neighborhood Hits	812	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR32_HUMAN
θ value	2.13673e-09 (rank : 130)	NC score	0.772463 (rank : 125)
Query Neighborhood Hits	812	Target Neighborhood Hits	270	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR49_HUMAN
θ value	2.13673e-09 (rank : 131)	NC score	0.826272 (rank : 59)
Query Neighborhood Hits	812	Target Neighborhood Hits	282	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

AN30A_HUMAN
θ value	2.79066e-09 (rank : 132)	NC score	0.568156 (rank : 208)
Query Neighborhood Hits	812	Target Neighborhood Hits	1119	Shared Neighborhood Hits	328
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

AN36B_HUMAN
θ value	2.79066e-09 (rank : 133)	NC score	0.775659 (rank : 122)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	281
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ASB8_HUMAN
θ value	2.79066e-09 (rank : 134)	NC score	0.823859 (rank : 63)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASZ1_HUMAN
θ value	2.79066e-09 (rank : 135)	NC score	0.803980 (rank : 91)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MAGE1_HUMAN
θ value	2.79066e-09 (rank : 136)	NC score	0.110624 (rank : 327)
Query Neighborhood Hits	812	Target Neighborhood Hits	1389	Shared Neighborhood Hits	285
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

POT15_HUMAN
θ value	3.64472e-09 (rank : 137)	NC score	0.703183 (rank : 160)
Query Neighborhood Hits	812	Target Neighborhood Hits	893	Shared Neighborhood Hits	314
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

UACA_MOUSE
θ value	3.64472e-09 (rank : 138)	NC score	0.465078 (rank : 243)
Query Neighborhood Hits	812	Target Neighborhood Hits	1620	Shared Neighborhood Hits	333
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANKR7_HUMAN
θ value	4.76016e-09 (rank : 139)	NC score	0.792385 (rank : 106)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	274
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANKR5_MOUSE
θ value	6.21693e-09 (rank : 140)	NC score	0.808756 (rank : 86)
Query Neighborhood Hits	812	Target Neighborhood Hits	298	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

OSBL1_MOUSE
θ value	6.21693e-09 (rank : 141)	NC score	0.649289 (rank : 179)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	283
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR21_HUMAN
θ value	8.11959e-09 (rank : 142)	NC score	0.703721 (rank : 159)
Query Neighborhood Hits	812	Target Neighborhood Hits	864	Shared Neighborhood Hits	310
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASB8_MOUSE
θ value	8.11959e-09 (rank : 143)	NC score	0.824477 (rank : 61)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

POTE8_HUMAN
θ value	1.06045e-08 (rank : 144)	NC score	0.748939 (rank : 138)
Query Neighborhood Hits	812	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

USH1G_HUMAN
θ value	1.06045e-08 (rank : 145)	NC score	0.761152 (rank : 130)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	1.06045e-08 (rank : 146)	NC score	0.760984 (rank : 131)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANKR5_HUMAN
θ value	1.38499e-08 (rank : 147)	NC score	0.805521 (rank : 89)
Query Neighborhood Hits	812	Target Neighborhood Hits	297	Shared Neighborhood Hits	281
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB12_MOUSE
θ value	1.38499e-08 (rank : 148)	NC score	0.787439 (rank : 111)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR22_HUMAN
θ value	1.80886e-08 (rank : 149)	NC score	0.792179 (rank : 107)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	238
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR15_HUMAN
θ value	3.08544e-08 (rank : 150)	NC score	0.714340 (rank : 154)
Query Neighborhood Hits	812	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANRA2_HUMAN
θ value	3.08544e-08 (rank : 151)	NC score	0.797221 (rank : 103)
Query Neighborhood Hits	812	Target Neighborhood Hits	288	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR10_MOUSE
θ value	4.0297e-08 (rank : 152)	NC score	0.800983 (rank : 96)
Query Neighborhood Hits	812	Target Neighborhood Hits	273	Shared Neighborhood Hits	264
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

KRIT1_HUMAN
θ value	4.0297e-08 (rank : 153)	NC score	0.690925 (rank : 166)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	221
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

NOTC2_HUMAN
θ value	4.0297e-08 (rank : 154)	NC score	0.397776 (rank : 261)
Query Neighborhood Hits	812	Target Neighborhood Hits	1113	Shared Neighborhood Hits	370
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	4.0297e-08 (rank : 155)	NC score	0.394701 (rank : 263)
Query Neighborhood Hits	812	Target Neighborhood Hits	1069	Shared Neighborhood Hits	347
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_MOUSE
θ value	4.0297e-08 (rank : 156)	NC score	0.403989 (rank : 259)
Query Neighborhood Hits	812	Target Neighborhood Hits	975	Shared Neighborhood Hits	339
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ASZ1_MOUSE
θ value	5.26297e-08 (rank : 157)	NC score	0.798980 (rank : 99)
Query Neighborhood Hits	812	Target Neighborhood Hits	319	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

NOTC3_HUMAN
θ value	5.26297e-08 (rank : 158)	NC score	0.403136 (rank : 260)
Query Neighborhood Hits	812	Target Neighborhood Hits	1062	Shared Neighborhood Hits	354
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANR32_MOUSE
θ value	6.87365e-08 (rank : 159)	NC score	0.759684 (rank : 132)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANRA2_MOUSE
θ value	8.97725e-08 (rank : 160)	NC score	0.793724 (rank : 105)
Query Neighborhood Hits	812	Target Neighborhood Hits	287	Shared Neighborhood Hits	278
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

NFH_MOUSE
θ value	8.97725e-08 (rank : 161)	NC score	0.087252 (rank : 400)
Query Neighborhood Hits	812	Target Neighborhood Hits	2247	Shared Neighborhood Hits	291
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ASB16_HUMAN
θ value	1.17247e-07 (rank : 162)	NC score	0.811355 (rank : 83)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	269
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NOTC1_HUMAN
θ value	1.17247e-07 (rank : 163)	NC score	0.396089 (rank : 262)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	309
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SON_HUMAN
θ value	1.53129e-07 (rank : 164)	NC score	0.117159 (rank : 320)
Query Neighborhood Hits	812	Target Neighborhood Hits	1568	Shared Neighborhood Hits	286
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CDN2D_MOUSE
θ value	1.99992e-07 (rank : 165)	NC score	0.802641 (rank : 92)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	264
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

NFKB1_HUMAN
θ value	1.99992e-07 (rank : 166)	NC score	0.700251 (rank : 162)
Query Neighborhood Hits	812	Target Neighborhood Hits	306	Shared Neighborhood Hits	274
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

CDN2D_HUMAN
θ value	2.61198e-07 (rank : 167)	NC score	0.810941 (rank : 85)
Query Neighborhood Hits	812	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

NFKB1_MOUSE
θ value	2.61198e-07 (rank : 168)	NC score	0.699707 (rank : 163)
Query Neighborhood Hits	812	Target Neighborhood Hits	300	Shared Neighborhood Hits	271
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB2_HUMAN
θ value	2.61198e-07 (rank : 169)	NC score	0.693752 (rank : 165)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	283
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

BCOR_HUMAN
θ value	3.41135e-07 (rank : 170)	NC score	0.698042 (rank : 164)
Query Neighborhood Hits	812	Target Neighborhood Hits	609	Shared Neighborhood Hits	339
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	3.41135e-07 (rank : 171)	NC score	0.705298 (rank : 157)
Query Neighborhood Hits	812	Target Neighborhood Hits	521	Shared Neighborhood Hits	311
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

IKBB_MOUSE
θ value	3.41135e-07 (rank : 172)	NC score	0.762819 (rank : 129)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ACBD6_MOUSE
θ value	4.45536e-07 (rank : 173)	NC score	0.774177 (rank : 124)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	287
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR47_MOUSE
θ value	4.45536e-07 (rank : 174)	NC score	0.710610 (rank : 156)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANS4B_HUMAN
θ value	4.45536e-07 (rank : 175)	NC score	0.751464 (rank : 136)
Query Neighborhood Hits	812	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ACBD6_HUMAN
θ value	5.81887e-07 (rank : 176)	NC score	0.767668 (rank : 127)
Query Neighborhood Hits	812	Target Neighborhood Hits	304	Shared Neighborhood Hits	284
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

LRRK1_MOUSE
θ value	5.81887e-07 (rank : 177)	NC score	0.132937 (rank : 304)
Query Neighborhood Hits	812	Target Neighborhood Hits	1267	Shared Neighborhood Hits	174
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

ABTB2_HUMAN
θ value	7.59969e-07 (rank : 178)	NC score	0.579121 (rank : 203)
Query Neighborhood Hits	812	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

OSTF1_HUMAN
θ value	7.59969e-07 (rank : 179)	NC score	0.648647 (rank : 180)
Query Neighborhood Hits	812	Target Neighborhood Hits	466	Shared Neighborhood Hits	300
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

EPHA2_HUMAN
θ value	9.92553e-07 (rank : 180)	NC score	0.104685 (rank : 355)
Query Neighborhood Hits	812	Target Neighborhood Hits	1021	Shared Neighborhood Hits	89
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

NFKB2_MOUSE
θ value	9.92553e-07 (rank : 181)	NC score	0.678407 (rank : 172)
Query Neighborhood Hits	812	Target Neighborhood Hits	326	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

OSTF1_MOUSE
θ value	9.92553e-07 (rank : 182)	NC score	0.664353 (rank : 175)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	302
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ASB1_MOUSE
θ value	1.29631e-06 (rank : 183)	NC score	0.777480 (rank : 119)
Query Neighborhood Hits	812	Target Neighborhood Hits	292	Shared Neighborhood Hits	275
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENB5_HUMAN
θ value	1.29631e-06 (rank : 184)	NC score	0.540702 (rank : 216)
Query Neighborhood Hits	812	Target Neighborhood Hits	395	Shared Neighborhood Hits	268
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

PRRT3_HUMAN
θ value	1.29631e-06 (rank : 185)	NC score	0.132560 (rank : 306)
Query Neighborhood Hits	812	Target Neighborhood Hits	998	Shared Neighborhood Hits	238
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ANR26_MOUSE
θ value	1.69304e-06 (rank : 186)	NC score	0.442136 (rank : 249)
Query Neighborhood Hits	812	Target Neighborhood Hits	1554	Shared Neighborhood Hits	331
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

EPHA2_MOUSE
θ value	1.69304e-06 (rank : 187)	NC score	0.104739 (rank : 353)
Query Neighborhood Hits	812	Target Neighborhood Hits	1020	Shared Neighborhood Hits	88
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

A20A1_HUMAN
θ value	2.88788e-06 (rank : 188)	NC score	0.631062 (rank : 189)
Query Neighborhood Hits	812	Target Neighborhood Hits	698	Shared Neighborhood Hits	284
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANS4B_MOUSE
θ value	2.88788e-06 (rank : 189)	NC score	0.738955 (rank : 147)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	258
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

EPHA5_HUMAN
θ value	2.88788e-06 (rank : 190)	NC score	0.107927 (rank : 337)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

PA2G6_HUMAN
θ value	2.88788e-06 (rank : 191)	NC score	0.801761 (rank : 93)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

TRPV5_MOUSE
θ value	2.88788e-06 (rank : 192)	NC score	0.492483 (rank : 233)
Query Neighborhood Hits	812	Target Neighborhood Hits	278	Shared Neighborhood Hits	248
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

A20A2_HUMAN
θ value	3.77169e-06 (rank : 193)	NC score	0.632041 (rank : 188)
Query Neighborhood Hits	812	Target Neighborhood Hits	716	Shared Neighborhood Hits	289
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	3.77169e-06 (rank : 194)	NC score	0.632699 (rank : 187)
Query Neighborhood Hits	812	Target Neighborhood Hits	692	Shared Neighborhood Hits	290
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	3.77169e-06 (rank : 195)	NC score	0.628099 (rank : 191)
Query Neighborhood Hits	812	Target Neighborhood Hits	710	Shared Neighborhood Hits	289
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR26_HUMAN
θ value	3.77169e-06 (rank : 196)	NC score	0.423186 (rank : 252)
Query Neighborhood Hits	812	Target Neighborhood Hits	1614	Shared Neighborhood Hits	342
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR47_HUMAN
θ value	3.77169e-06 (rank : 197)	NC score	0.687680 (rank : 167)
Query Neighborhood Hits	812	Target Neighborhood Hits	369	Shared Neighborhood Hits	272
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

DDFL1_MOUSE
θ value	3.77169e-06 (rank : 198)	NC score	0.481497 (rank : 235)
Query Neighborhood Hits	812	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

RFXK_HUMAN
θ value	3.77169e-06 (rank : 199)	NC score	0.786247 (rank : 114)
Query Neighborhood Hits	812	Target Neighborhood Hits	282	Shared Neighborhood Hits	269
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

SNCAP_HUMAN
θ value	3.77169e-06 (rank : 200)	NC score	0.715942 (rank : 153)
Query Neighborhood Hits	812	Target Neighborhood Hits	313	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANKY2_HUMAN
θ value	4.92598e-06 (rank : 201)	NC score	0.726100 (rank : 151)
Query Neighborhood Hits	812	Target Neighborhood Hits	306	Shared Neighborhood Hits	261
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASPP2_HUMAN
θ value	4.92598e-06 (rank : 202)	NC score	0.575468 (rank : 204)
Query Neighborhood Hits	812	Target Neighborhood Hits	1156	Shared Neighborhood Hits	397
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANR25_HUMAN
θ value	6.43352e-06 (rank : 203)	NC score	0.666363 (rank : 174)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	281
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

EPHB3_HUMAN
θ value	6.43352e-06 (rank : 204)	NC score	0.105721 (rank : 347)
Query Neighborhood Hits	812	Target Neighborhood Hits	996	Shared Neighborhood Hits	91
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

ANKY2_MOUSE
θ value	8.40245e-06 (rank : 205)	NC score	0.703771 (rank : 158)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	262
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

HECD1_HUMAN
θ value	8.40245e-06 (rank : 206)	NC score	0.585653 (rank : 200)
Query Neighborhood Hits	812	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

EPHA1_MOUSE
θ value	1.09739e-05 (rank : 207)	NC score	0.105607 (rank : 348)
Query Neighborhood Hits	812	Target Neighborhood Hits	958	Shared Neighborhood Hits	93
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA7_HUMAN
θ value	1.09739e-05 (rank : 208)	NC score	0.105893 (rank : 344)
Query Neighborhood Hits	812	Target Neighborhood Hits	1053	Shared Neighborhood Hits	98
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

MAST4_HUMAN
θ value	1.09739e-05 (rank : 209)	NC score	0.055878 (rank : 688)
Query Neighborhood Hits	812	Target Neighborhood Hits	1804	Shared Neighborhood Hits	262
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

POT14_HUMAN
θ value	1.09739e-05 (rank : 210)	NC score	0.686277 (rank : 169)
Query Neighborhood Hits	812	Target Neighborhood Hits	403	Shared Neighborhood Hits	276
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

POT22_HUMAN
θ value	1.09739e-05 (rank : 211)	NC score	0.647017 (rank : 182)
Query Neighborhood Hits	812	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR45_HUMAN
θ value	1.43324e-05 (rank : 212)	NC score	0.588529 (rank : 199)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	187
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASPP1_MOUSE
θ value	1.43324e-05 (rank : 213)	NC score	0.561977 (rank : 211)
Query Neighborhood Hits	812	Target Neighborhood Hits	1244	Shared Neighborhood Hits	451
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EPHB3_MOUSE
θ value	1.43324e-05 (rank : 214)	NC score	0.104501 (rank : 357)
Query Neighborhood Hits	812	Target Neighborhood Hits	996	Shared Neighborhood Hits	88
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

AN13B_HUMAN
θ value	1.87187e-05 (rank : 215)	NC score	0.528866 (rank : 225)
Query Neighborhood Hits	812	Target Neighborhood Hits	265	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	1.87187e-05 (rank : 216)	NC score	0.529560 (rank : 223)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	252
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANR37_MOUSE
θ value	1.87187e-05 (rank : 217)	NC score	0.716081 (rank : 152)
Query Neighborhood Hits	812	Target Neighborhood Hits	237	Shared Neighborhood Hits	233
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

EPHA1_HUMAN
θ value	1.87187e-05 (rank : 218)	NC score	0.105498 (rank : 349)
Query Neighborhood Hits	812	Target Neighborhood Hits	997	Shared Neighborhood Hits	98
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA5_MOUSE
θ value	1.87187e-05 (rank : 219)	NC score	0.098367 (rank : 376)
Query Neighborhood Hits	812	Target Neighborhood Hits	950	Shared Neighborhood Hits	86
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

ANR25_MOUSE
θ value	2.44474e-05 (rank : 220)	NC score	0.657107 (rank : 177)
Query Neighborhood Hits	812	Target Neighborhood Hits	398	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR38_HUMAN
θ value	2.44474e-05 (rank : 221)	NC score	0.647674 (rank : 181)
Query Neighborhood Hits	812	Target Neighborhood Hits	443	Shared Neighborhood Hits	257
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASB1_HUMAN
θ value	2.44474e-05 (rank : 222)	NC score	0.776329 (rank : 120)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

EPHA7_MOUSE
θ value	2.44474e-05 (rank : 223)	NC score	0.104903 (rank : 351)
Query Neighborhood Hits	812	Target Neighborhood Hits	1025	Shared Neighborhood Hits	90
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

GLSL_MOUSE
θ value	2.44474e-05 (rank : 224)	NC score	0.524856 (rank : 229)
Query Neighborhood Hits	812	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

NACAM_MOUSE
θ value	2.44474e-05 (rank : 225)	NC score	0.137465 (rank : 302)
Query Neighborhood Hits	812	Target Neighborhood Hits	1866	Shared Neighborhood Hits	315
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ANR33_MOUSE
θ value	3.19293e-05 (rank : 226)	NC score	0.671176 (rank : 173)
Query Neighborhood Hits	812	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CDN2B_MOUSE
θ value	3.19293e-05 (rank : 227)	NC score	0.646197 (rank : 184)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ASPP1_HUMAN
θ value	4.1701e-05 (rank : 228)	NC score	0.570717 (rank : 206)
Query Neighborhood Hits	812	Target Neighborhood Hits	956	Shared Neighborhood Hits	372
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MTPN_HUMAN
θ value	4.1701e-05 (rank : 229)	NC score	0.798087 (rank : 102)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	4.1701e-05 (rank : 230)	NC score	0.801474 (rank : 95)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

NUD12_MOUSE
θ value	4.1701e-05 (rank : 231)	NC score	0.567601 (rank : 209)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ABTB2_MOUSE
θ value	5.44631e-05 (rank : 232)	NC score	0.564902 (rank : 210)
Query Neighborhood Hits	812	Target Neighborhood Hits	414	Shared Neighborhood Hits	240
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR37_HUMAN
θ value	5.44631e-05 (rank : 233)	NC score	0.729393 (rank : 150)
Query Neighborhood Hits	812	Target Neighborhood Hits	247	Shared Neighborhood Hits	243
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

EPHB1_HUMAN
θ value	5.44631e-05 (rank : 234)	NC score	0.101827 (rank : 367)
Query Neighborhood Hits	812	Target Neighborhood Hits	988	Shared Neighborhood Hits	90
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB4_HUMAN
θ value	5.44631e-05 (rank : 235)	NC score	0.104706 (rank : 354)
Query Neighborhood Hits	812	Target Neighborhood Hits	1056	Shared Neighborhood Hits	99
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

LRRK1_HUMAN
θ value	5.44631e-05 (rank : 236)	NC score	0.109599 (rank : 331)
Query Neighborhood Hits	812	Target Neighborhood Hits	1237	Shared Neighborhood Hits	149
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

CENB2_HUMAN
θ value	7.1131e-05 (rank : 237)	NC score	0.528887 (rank : 224)
Query Neighborhood Hits	812	Target Neighborhood Hits	425	Shared Neighborhood Hits	261
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DDEF1_MOUSE
θ value	9.29e-05 (rank : 238)	NC score	0.338158 (rank : 272)
Query Neighborhood Hits	812	Target Neighborhood Hits	592	Shared Neighborhood Hits	275
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	9.29e-05 (rank : 239)	NC score	0.421586 (rank : 253)
Query Neighborhood Hits	812	Target Neighborhood Hits	599	Shared Neighborhood Hits	318
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	9.29e-05 (rank : 240)	NC score	0.419061 (rank : 254)
Query Neighborhood Hits	812	Target Neighborhood Hits	625	Shared Neighborhood Hits	323
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

RGS3_MOUSE
θ value	9.29e-05 (rank : 241)	NC score	0.103638 (rank : 360)
Query Neighborhood Hits	812	Target Neighborhood Hits	1621	Shared Neighborhood Hits	297
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TRPV6_MOUSE
θ value	9.29e-05 (rank : 242)	NC score	0.535414 (rank : 219)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	256
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR45_MOUSE
θ value	0.000121331 (rank : 243)	NC score	0.629830 (rank : 190)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

EPHB4_MOUSE
θ value	0.000121331 (rank : 244)	NC score	0.103530 (rank : 362)
Query Neighborhood Hits	812	Target Neighborhood Hits	1013	Shared Neighborhood Hits	91
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

ANR38_MOUSE
θ value	0.000158464 (rank : 245)	NC score	0.622068 (rank : 192)
Query Neighborhood Hits	812	Target Neighborhood Hits	512	Shared Neighborhood Hits	253
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASB12_HUMAN
θ value	0.000158464 (rank : 246)	NC score	0.781050 (rank : 118)
Query Neighborhood Hits	812	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

CT086_HUMAN
θ value	0.000158464 (rank : 247)	NC score	0.798557 (rank : 100)
Query Neighborhood Hits	812	Target Neighborhood Hits	277	Shared Neighborhood Hits	273
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

IKBB_HUMAN
θ value	0.000158464 (rank : 248)	NC score	0.757329 (rank : 133)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

MYO9B_HUMAN
θ value	0.000158464 (rank : 249)	NC score	0.030170 (rank : 909)
Query Neighborhood Hits	812	Target Neighborhood Hits	641	Shared Neighborhood Hits	112
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ANR46_HUMAN
θ value	0.00020696 (rank : 250)	NC score	0.786635 (rank : 113)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	276
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

EPHB2_HUMAN
θ value	0.00020696 (rank : 251)	NC score	0.104465 (rank : 358)
Query Neighborhood Hits	812	Target Neighborhood Hits	983	Shared Neighborhood Hits	89
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.00020696 (rank : 252)	NC score	0.103067 (rank : 365)
Query Neighborhood Hits	812	Target Neighborhood Hits	982	Shared Neighborhood Hits	89
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

GRIN1_HUMAN
θ value	0.00020696 (rank : 253)	NC score	0.101498 (rank : 368)
Query Neighborhood Hits	812	Target Neighborhood Hits	681	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

AN13A_HUMAN
θ value	0.000270298 (rank : 254)	NC score	0.466298 (rank : 242)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

GLSL_HUMAN
θ value	0.000270298 (rank : 255)	NC score	0.528415 (rank : 226)
Query Neighborhood Hits	812	Target Neighborhood Hits	211	Shared Neighborhood Hits	204
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

CD2A1_HUMAN
θ value	0.00035302 (rank : 256)	NC score	0.618190 (rank : 193)
Query Neighborhood Hits	812	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CENG3_HUMAN
θ value	0.00035302 (rank : 257)	NC score	0.314034 (rank : 277)
Query Neighborhood Hits	812	Target Neighborhood Hits	455	Shared Neighborhood Hits	237
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.00035302 (rank : 258)	NC score	0.314315 (rank : 276)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	238
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ANR41_HUMAN
θ value	0.000461057 (rank : 259)	NC score	0.740682 (rank : 144)
Query Neighborhood Hits	812	Target Neighborhood Hits	332	Shared Neighborhood Hits	272
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

CD2A1_MOUSE
θ value	0.000461057 (rank : 260)	NC score	0.683971 (rank : 170)
Query Neighborhood Hits	812	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CT012_MOUSE
θ value	0.000461057 (rank : 261)	NC score	0.472863 (rank : 239)
Query Neighborhood Hits	812	Target Neighborhood Hits	229	Shared Neighborhood Hits	184
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

TRPV6_HUMAN
θ value	0.000461057 (rank : 262)	NC score	0.451974 (rank : 245)
Query Neighborhood Hits	812	Target Neighborhood Hits	262	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

AN36A_HUMAN
θ value	0.000602161 (rank : 263)	NC score	0.732941 (rank : 149)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR46_MOUSE
θ value	0.000602161 (rank : 264)	NC score	0.781316 (rank : 117)
Query Neighborhood Hits	812	Target Neighborhood Hits	274	Shared Neighborhood Hits	270
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

BSN_MOUSE
θ value	0.000602161 (rank : 265)	NC score	0.124447 (rank : 313)
Query Neighborhood Hits	812	Target Neighborhood Hits	2057	Shared Neighborhood Hits	347
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

IASPP_MOUSE
θ value	0.000602161 (rank : 266)	NC score	0.535119 (rank : 220)
Query Neighborhood Hits	812	Target Neighborhood Hits	1024	Shared Neighborhood Hits	452
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CT012_HUMAN
θ value	0.000786445 (rank : 267)	NC score	0.436095 (rank : 251)
Query Neighborhood Hits	812	Target Neighborhood Hits	205	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

EPHA6_HUMAN
θ value	0.000786445 (rank : 268)	NC score	0.107344 (rank : 338)
Query Neighborhood Hits	812	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA8_HUMAN
θ value	0.000786445 (rank : 269)	NC score	0.101385 (rank : 370)
Query Neighborhood Hits	812	Target Neighborhood Hits	956	Shared Neighborhood Hits	83
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	0.000786445 (rank : 270)	NC score	0.103330 (rank : 363)
Query Neighborhood Hits	812	Target Neighborhood Hits	969	Shared Neighborhood Hits	84
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

IASPP_HUMAN
θ value	0.000786445 (rank : 271)	NC score	0.575222 (rank : 205)
Query Neighborhood Hits	812	Target Neighborhood Hits	688	Shared Neighborhood Hits	375
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NCOA6_HUMAN
θ value	0.000786445 (rank : 272)	NC score	0.120387 (rank : 316)
Query Neighborhood Hits	812	Target Neighborhood Hits	1202	Shared Neighborhood Hits	250
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NOTC1_MOUSE
θ value	0.000786445 (rank : 273)	NC score	0.335419 (rank : 274)
Query Neighborhood Hits	812	Target Neighborhood Hits	916	Shared Neighborhood Hits	293
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ASB14_HUMAN
θ value	0.00134147 (rank : 274)	NC score	0.530013 (rank : 222)
Query Neighborhood Hits	812	Target Neighborhood Hits	187	Shared Neighborhood Hits	176
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

DDFL1_HUMAN
θ value	0.00134147 (rank : 275)	NC score	0.389814 (rank : 264)
Query Neighborhood Hits	812	Target Neighborhood Hits	353	Shared Neighborhood Hits	249
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

GLSK_HUMAN
θ value	0.00134147 (rank : 276)	NC score	0.480533 (rank : 236)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GRAP_HUMAN
θ value	0.00134147 (rank : 277)	NC score	0.059022 (rank : 612)
Query Neighborhood Hits	812	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ITSN1_MOUSE
θ value	0.00134147 (rank : 278)	NC score	0.054649 (rank : 712)
Query Neighborhood Hits	812	Target Neighborhood Hits	1669	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NUD12_HUMAN
θ value	0.00134147 (rank : 279)	NC score	0.533077 (rank : 221)
Query Neighborhood Hits	812	Target Neighborhood Hits	222	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

GLI2_HUMAN
θ value	0.00175202 (rank : 280)	NC score	-0.000823 (rank : 1088)
Query Neighborhood Hits	812	Target Neighborhood Hits	971	Shared Neighborhood Hits	103
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

TRPV5_HUMAN
θ value	0.00175202 (rank : 281)	NC score	0.447612 (rank : 247)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

CO5A2_HUMAN
θ value	0.00228821 (rank : 282)	NC score	0.062705 (rank : 541)
Query Neighborhood Hits	812	Target Neighborhood Hits	760	Shared Neighborhood Hits	182
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

OGFR_HUMAN
θ value	0.00228821 (rank : 283)	NC score	0.134108 (rank : 303)
Query Neighborhood Hits	812	Target Neighborhood Hits	1582	Shared Neighborhood Hits	305
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TAU_MOUSE
θ value	0.00228821 (rank : 284)	NC score	0.082535 (rank : 418)
Query Neighborhood Hits	812	Target Neighborhood Hits	502	Shared Neighborhood Hits	127
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ANR43_MOUSE
θ value	0.00298849 (rank : 285)	NC score	0.595983 (rank : 195)
Query Neighborhood Hits	812	Target Neighborhood Hits	214	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

EPHA6_MOUSE
θ value	0.00298849 (rank : 286)	NC score	0.105806 (rank : 345)
Query Neighborhood Hits	812	Target Neighborhood Hits	946	Shared Neighborhood Hits	83
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB6_MOUSE
θ value	0.00298849 (rank : 287)	NC score	0.108086 (rank : 336)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	86
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

RGS3_HUMAN
θ value	0.00298849 (rank : 288)	NC score	0.078328 (rank : 437)
Query Neighborhood Hits	812	Target Neighborhood Hits	1375	Shared Neighborhood Hits	247
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SASH1_HUMAN
θ value	0.00298849 (rank : 289)	NC score	0.123200 (rank : 314)
Query Neighborhood Hits	812	Target Neighborhood Hits	292	Shared Neighborhood Hits	120
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

CSF1_HUMAN
θ value	0.00390308 (rank : 290)	NC score	0.081615 (rank : 423)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

EPHAA_HUMAN
θ value	0.00390308 (rank : 291)	NC score	0.104015 (rank : 359)
Query Neighborhood Hits	812	Target Neighborhood Hits	960	Shared Neighborhood Hits	87
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

GIT2_MOUSE
θ value	0.00390308 (rank : 292)	NC score	0.497580 (rank : 232)
Query Neighborhood Hits	812	Target Neighborhood Hits	323	Shared Neighborhood Hits	259
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

K1802_MOUSE
θ value	0.00390308 (rank : 293)	NC score	0.084291 (rank : 413)
Query Neighborhood Hits	812	Target Neighborhood Hits	1596	Shared Neighborhood Hits	243
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LIPB2_HUMAN
θ value	0.00390308 (rank : 294)	NC score	0.071294 (rank : 476)
Query Neighborhood Hits	812	Target Neighborhood Hits	599	Shared Neighborhood Hits	54
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

TARA_HUMAN
θ value	0.00390308 (rank : 295)	NC score	0.082701 (rank : 416)
Query Neighborhood Hits	812	Target Neighborhood Hits	1626	Shared Neighborhood Hits	248
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AN13C_HUMAN
θ value	0.00509761 (rank : 296)	NC score	0.518118 (rank : 230)
Query Neighborhood Hits	812	Target Neighborhood Hits	241	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13A_MOUSE
θ value	0.00665767 (rank : 297)	NC score	0.438565 (rank : 250)
Query Neighborhood Hits	812	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

AN13C_MOUSE
θ value	0.00665767 (rank : 298)	NC score	0.507218 (rank : 231)
Query Neighborhood Hits	812	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANKZ1_MOUSE
θ value	0.00665767 (rank : 299)	NC score	0.347529 (rank : 268)
Query Neighborhood Hits	812	Target Neighborhood Hits	208	Shared Neighborhood Hits	156
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

FMNL_HUMAN
θ value	0.00665767 (rank : 300)	NC score	0.076178 (rank : 448)
Query Neighborhood Hits	812	Target Neighborhood Hits	529	Shared Neighborhood Hits	126
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GIT2_HUMAN
θ value	0.00665767 (rank : 301)	NC score	0.461640 (rank : 244)
Query Neighborhood Hits	812	Target Neighborhood Hits	381	Shared Neighborhood Hits	251
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

MDC1_HUMAN
θ value	0.00665767 (rank : 302)	NC score	0.117157 (rank : 321)
Query Neighborhood Hits	812	Target Neighborhood Hits	1446	Shared Neighborhood Hits	241
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TNK1_HUMAN
θ value	0.00665767 (rank : 303)	NC score	0.066510 (rank : 499)
Query Neighborhood Hits	812	Target Neighborhood Hits	815	Shared Neighborhood Hits	77
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

DGKZ_MOUSE
θ value	0.00869519 (rank : 304)	NC score	0.345673 (rank : 269)
Query Neighborhood Hits	812	Target Neighborhood Hits	542	Shared Neighborhood Hits	208
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

EPHB6_HUMAN
θ value	0.00869519 (rank : 305)	NC score	0.108344 (rank : 335)
Query Neighborhood Hits	812	Target Neighborhood Hits	912	Shared Neighborhood Hits	87
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

SASH1_MOUSE
θ value	0.00869519 (rank : 306)	NC score	0.128168 (rank : 308)
Query Neighborhood Hits	812	Target Neighborhood Hits	263	Shared Neighborhood Hits	103
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

TCGAP_HUMAN
θ value	0.00869519 (rank : 307)	NC score	0.090547 (rank : 390)
Query Neighborhood Hits	812	Target Neighborhood Hits	872	Shared Neighborhood Hits	230
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRPC3_HUMAN
θ value	0.00869519 (rank : 308)	NC score	0.110006 (rank : 329)
Query Neighborhood Hits	812	Target Neighborhood Hits	137	Shared Neighborhood Hits	82
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

EPHA4_HUMAN
θ value	0.0113563 (rank : 309)	NC score	0.099530 (rank : 375)
Query Neighborhood Hits	812	Target Neighborhood Hits	975	Shared Neighborhood Hits	84
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	0.0113563 (rank : 310)	NC score	0.099741 (rank : 374)
Query Neighborhood Hits	812	Target Neighborhood Hits	982	Shared Neighborhood Hits	85
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

RFXK_MOUSE
θ value	0.0113563 (rank : 311)	NC score	0.766690 (rank : 128)
Query Neighborhood Hits	812	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

SPEG_MOUSE
θ value	0.0113563 (rank : 312)	NC score	0.041235 (rank : 840)
Query Neighborhood Hits	812	Target Neighborhood Hits	1959	Shared Neighborhood Hits	249
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TEX14_MOUSE
θ value	0.0113563 (rank : 313)	NC score	0.406967 (rank : 256)
Query Neighborhood Hits	812	Target Neighborhood Hits	1333	Shared Neighborhood Hits	329
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR33_HUMAN
θ value	0.0148317 (rank : 314)	NC score	0.646827 (rank : 183)
Query Neighborhood Hits	812	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CLR59_HUMAN
θ value	0.0148317 (rank : 315)	NC score	0.298285 (rank : 280)
Query Neighborhood Hits	812	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

BSN_HUMAN
θ value	0.0193708 (rank : 316)	NC score	0.112761 (rank : 325)
Query Neighborhood Hits	812	Target Neighborhood Hits	1537	Shared Neighborhood Hits	282
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CLPB_MOUSE
θ value	0.0193708 (rank : 317)	NC score	0.642895 (rank : 185)
Query Neighborhood Hits	812	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

LIPB2_MOUSE
θ value	0.0193708 (rank : 318)	NC score	0.072376 (rank : 467)
Query Neighborhood Hits	812	Target Neighborhood Hits	570	Shared Neighborhood Hits	69
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MAGD4_HUMAN
θ value	0.0193708 (rank : 319)	NC score	0.036343 (rank : 870)
Query Neighborhood Hits	812	Target Neighborhood Hits	338	Shared Neighborhood Hits	83
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

PCLO_MOUSE
θ value	0.0193708 (rank : 320)	NC score	0.105755 (rank : 346)
Query Neighborhood Hits	812	Target Neighborhood Hits	2275	Shared Neighborhood Hits	354
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SARM1_HUMAN
θ value	0.0193708 (rank : 321)	NC score	0.094333 (rank : 386)
Query Neighborhood Hits	812	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SARM1_MOUSE
θ value	0.0193708 (rank : 322)	NC score	0.106599 (rank : 341)
Query Neighborhood Hits	812	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SHAN2_MOUSE
θ value	0.0193708 (rank : 323)	NC score	0.118215 (rank : 318)
Query Neighborhood Hits	812	Target Neighborhood Hits	446	Shared Neighborhood Hits	134
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STAC_MOUSE
θ value	0.0193708 (rank : 324)	NC score	0.073847 (rank : 460)
Query Neighborhood Hits	812	Target Neighborhood Hits	268	Shared Neighborhood Hits	67
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
θ value	0.0193708 (rank : 325)	NC score	0.071916 (rank : 474)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	66
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	0.0193708 (rank : 326)	NC score	0.072200 (rank : 470)
Query Neighborhood Hits	812	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TRPV2_MOUSE
θ value	0.0193708 (rank : 327)	NC score	0.165938 (rank : 296)
Query Neighborhood Hits	812	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CRK_HUMAN
θ value	0.0252991 (rank : 328)	NC score	0.052354 (rank : 753)
Query Neighborhood Hits	812	Target Neighborhood Hits	308	Shared Neighborhood Hits	60
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GIT1_HUMAN
θ value	0.0252991 (rank : 329)	NC score	0.477049 (rank : 238)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	251
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.0252991 (rank : 330)	NC score	0.478180 (rank : 237)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	252
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

NCOA2_HUMAN
θ value	0.0252991 (rank : 331)	NC score	0.035022 (rank : 877)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	60
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

STAC_HUMAN
θ value	0.0252991 (rank : 332)	NC score	0.073310 (rank : 462)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TGON2_HUMAN
θ value	0.0252991 (rank : 333)	NC score	0.077550 (rank : 443)
Query Neighborhood Hits	812	Target Neighborhood Hits	1037	Shared Neighborhood Hits	164
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TNIK_HUMAN
θ value	0.0252991 (rank : 334)	NC score	0.033220 (rank : 886)
Query Neighborhood Hits	812	Target Neighborhood Hits	1570	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TRPC7_HUMAN
θ value	0.0252991 (rank : 335)	NC score	0.097130 (rank : 381)
Query Neighborhood Hits	812	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

ANR43_HUMAN
θ value	0.0330416 (rank : 336)	NC score	0.594303 (rank : 197)
Query Neighborhood Hits	812	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CENB1_HUMAN
θ value	0.0330416 (rank : 337)	NC score	0.527805 (rank : 227)
Query Neighborhood Hits	812	Target Neighborhood Hits	383	Shared Neighborhood Hits	266
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DGKI_HUMAN
θ value	0.0330416 (rank : 338)	NC score	0.341761 (rank : 270)
Query Neighborhood Hits	812	Target Neighborhood Hits	609	Shared Neighborhood Hits	223
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

ASB6_HUMAN
θ value	0.0431538 (rank : 339)	NC score	0.687187 (rank : 168)
Query Neighborhood Hits	812	Target Neighborhood Hits	256	Shared Neighborhood Hits	243
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CEND3_HUMAN
θ value	0.0431538 (rank : 340)	NC score	0.106947 (rank : 340)
Query Neighborhood Hits	812	Target Neighborhood Hits	275	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

MISS_MOUSE
θ value	0.0431538 (rank : 341)	NC score	0.078165 (rank : 438)
Query Neighborhood Hits	812	Target Neighborhood Hits	444	Shared Neighborhood Hits	128
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL3_HUMAN
θ value	0.0431538 (rank : 342)	NC score	0.097766 (rank : 378)
Query Neighborhood Hits	812	Target Neighborhood Hits	1644	Shared Neighborhood Hits	271
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SHAN2_HUMAN
θ value	0.0431538 (rank : 343)	NC score	0.112174 (rank : 326)
Query Neighborhood Hits	812	Target Neighborhood Hits	346	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

ZN206_HUMAN
θ value	0.0431538 (rank : 344)	NC score	-0.009949 (rank : 1103)
Query Neighborhood Hits	812	Target Neighborhood Hits	853	Shared Neighborhood Hits	67
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

IRX5_MOUSE
θ value	0.0563607 (rank : 345)	NC score	0.025898 (rank : 940)
Query Neighborhood Hits	812	Target Neighborhood Hits	324	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

MLL3_MOUSE
θ value	0.0563607 (rank : 346)	NC score	0.096863 (rank : 382)
Query Neighborhood Hits	812	Target Neighborhood Hits	1399	Shared Neighborhood Hits	244
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TAF4_HUMAN
θ value	0.0563607 (rank : 347)	NC score	0.124854 (rank : 312)
Query Neighborhood Hits	812	Target Neighborhood Hits	687	Shared Neighborhood Hits	169
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CBLB_MOUSE
θ value	0.0736092 (rank : 348)	NC score	0.030430 (rank : 908)
Query Neighborhood Hits	812	Target Neighborhood Hits	277	Shared Neighborhood Hits	43
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CNKR2_HUMAN
θ value	0.0736092 (rank : 349)	NC score	0.066336 (rank : 503)
Query Neighborhood Hits	812	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.0736092 (rank : 350)	NC score	0.066374 (rank : 502)
Query Neighborhood Hits	812	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CRK_MOUSE
θ value	0.0736092 (rank : 351)	NC score	0.049362 (rank : 796)
Query Neighborhood Hits	812	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GRAP_MOUSE
θ value	0.0736092 (rank : 352)	NC score	0.053927 (rank : 729)
Query Neighborhood Hits	812	Target Neighborhood Hits	309	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

HXA5_MOUSE
θ value	0.0736092 (rank : 353)	NC score	0.000436 (rank : 1083)
Query Neighborhood Hits	812	Target Neighborhood Hits	338	Shared Neighborhood Hits	19
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

MGR1_MOUSE
θ value	0.0736092 (rank : 354)	NC score	0.007813 (rank : 1052)
Query Neighborhood Hits	812	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MK15_HUMAN
θ value	0.0736092 (rank : 355)	NC score	0.031710 (rank : 898)
Query Neighborhood Hits	812	Target Neighborhood Hits	1038	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MUCDL_HUMAN
θ value	0.0736092 (rank : 356)	NC score	0.087267 (rank : 399)
Query Neighborhood Hits	812	Target Neighborhood Hits	777	Shared Neighborhood Hits	189
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PI5PA_MOUSE
θ value	0.0736092 (rank : 357)	NC score	0.068257 (rank : 489)
Query Neighborhood Hits	812	Target Neighborhood Hits	331	Shared Neighborhood Hits	101
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RERE_MOUSE
θ value	0.0736092 (rank : 358)	NC score	0.096098 (rank : 383)
Query Neighborhood Hits	812	Target Neighborhood Hits	785	Shared Neighborhood Hits	180
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SAM14_MOUSE
θ value	0.0736092 (rank : 359)	NC score	0.088572 (rank : 395)
Query Neighborhood Hits	812	Target Neighborhood Hits	91	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

TRPC3_MOUSE
θ value	0.0736092 (rank : 360)	NC score	0.100142 (rank : 372)
Query Neighborhood Hits	812	Target Neighborhood Hits	131	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPV2_HUMAN
θ value	0.0736092 (rank : 361)	NC score	0.208227 (rank : 291)
Query Neighborhood Hits	812	Target Neighborhood Hits	130	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

VASP_MOUSE
θ value	0.0736092 (rank : 362)	NC score	0.059541 (rank : 599)
Query Neighborhood Hits	812	Target Neighborhood Hits	195	Shared Neighborhood Hits	70
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CEND3_MOUSE
θ value	0.0961366 (rank : 363)	NC score	0.100515 (rank : 371)
Query Neighborhood Hits	812	Target Neighborhood Hits	228	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

FRS3_MOUSE
θ value	0.0961366 (rank : 364)	NC score	0.028702 (rank : 922)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	54
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

LIMD1_HUMAN
θ value	0.0961366 (rank : 365)	NC score	0.011601 (rank : 1031)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

OGFR_MOUSE
θ value	0.0961366 (rank : 366)	NC score	0.075047 (rank : 454)
Query Neighborhood Hits	812	Target Neighborhood Hits	584	Shared Neighborhood Hits	114
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OTU7B_HUMAN
θ value	0.0961366 (rank : 367)	NC score	0.020877 (rank : 971)
Query Neighborhood Hits	812	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

PAX3_MOUSE
θ value	0.0961366 (rank : 368)	NC score	0.005739 (rank : 1059)
Query Neighborhood Hits	812	Target Neighborhood Hits	478	Shared Neighborhood Hits	39
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

RUSC2_MOUSE
θ value	0.0961366 (rank : 369)	NC score	0.044620 (rank : 814)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	96
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

TRPC7_MOUSE
θ value	0.0961366 (rank : 370)	NC score	0.095459 (rank : 384)
Query Neighborhood Hits	812	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

ANKY1_HUMAN
θ value	0.125558 (rank : 371)	NC score	0.527170 (rank : 228)
Query Neighborhood Hits	812	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

IWS1_MOUSE
θ value	0.125558 (rank : 372)	NC score	0.064654 (rank : 513)
Query Neighborhood Hits	812	Target Neighborhood Hits	1258	Shared Neighborhood Hits	159
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LARP4_MOUSE
θ value	0.125558 (rank : 373)	NC score	0.063829 (rank : 525)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PAX3_HUMAN
θ value	0.125558 (rank : 374)	NC score	0.005685 (rank : 1060)
Query Neighborhood Hits	812	Target Neighborhood Hits	513	Shared Neighborhood Hits	46
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PDCD7_HUMAN
θ value	0.125558 (rank : 375)	NC score	0.055707 (rank : 691)
Query Neighborhood Hits	812	Target Neighborhood Hits	255	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

ULK1_MOUSE
θ value	0.125558 (rank : 376)	NC score	0.046756 (rank : 806)
Query Neighborhood Hits	812	Target Neighborhood Hits	1214	Shared Neighborhood Hits	164
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ANR40_HUMAN
θ value	0.163984 (rank : 377)	NC score	0.557736 (rank : 214)
Query Neighborhood Hits	812	Target Neighborhood Hits	224	Shared Neighborhood Hits	210
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	0.163984 (rank : 378)	NC score	0.557761 (rank : 213)
Query Neighborhood Hits	812	Target Neighborhood Hits	228	Shared Neighborhood Hits	211
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ASB6_MOUSE
θ value	0.163984 (rank : 379)	NC score	0.680418 (rank : 171)
Query Neighborhood Hits	812	Target Neighborhood Hits	264	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLPB_HUMAN
θ value	0.163984 (rank : 380)	NC score	0.558260 (rank : 212)
Query Neighborhood Hits	812	Target Neighborhood Hits	265	Shared Neighborhood Hits	234
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CO9A1_MOUSE
θ value	0.163984 (rank : 381)	NC score	0.040887 (rank : 843)
Query Neighborhood Hits	812	Target Neighborhood Hits	477	Shared Neighborhood Hits	112
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CSTF2_HUMAN
θ value	0.163984 (rank : 382)	NC score	0.012826 (rank : 1026)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	42
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DGKZ_HUMAN
θ value	0.163984 (rank : 383)	NC score	0.361240 (rank : 265)
Query Neighborhood Hits	812	Target Neighborhood Hits	551	Shared Neighborhood Hits	223
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

ETV3_HUMAN
θ value	0.163984 (rank : 384)	NC score	0.018179 (rank : 993)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	60
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

PRG4_MOUSE
θ value	0.163984 (rank : 385)	NC score	0.094431 (rank : 385)
Query Neighborhood Hits	812	Target Neighborhood Hits	624	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SALL3_HUMAN
θ value	0.163984 (rank : 386)	NC score	0.005344 (rank : 1062)
Query Neighborhood Hits	812	Target Neighborhood Hits	1066	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SON_MOUSE
θ value	0.163984 (rank : 387)	NC score	0.098128 (rank : 377)
Query Neighborhood Hits	812	Target Neighborhood Hits	957	Shared Neighborhood Hits	183
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZN409_HUMAN
θ value	0.163984 (rank : 388)	NC score	0.021517 (rank : 966)
Query Neighborhood Hits	812	Target Neighborhood Hits	842	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

AMPD2_HUMAN
θ value	0.21417 (rank : 389)	NC score	0.017021 (rank : 1001)
Query Neighborhood Hits	812	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q01433, Q14856, Q14857, Q16686, Q16687, Q16688, Q16729, Q96IA1, Q9UDX8, Q9UDX9, Q9UMU4	Gene names	AMPD2
Domain Architecture
Description	AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L).

CDN2B_HUMAN
θ value	0.21417 (rank : 390)	NC score	0.592125 (rank : 198)
Query Neighborhood Hits	812	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

K1543_MOUSE
θ value	0.21417 (rank : 391)	NC score	0.084613 (rank : 406)
Query Neighborhood Hits	812	Target Neighborhood Hits	497	Shared Neighborhood Hits	134
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LAD1_MOUSE
θ value	0.21417 (rank : 392)	NC score	0.079894 (rank : 431)
Query Neighborhood Hits	812	Target Neighborhood Hits	391	Shared Neighborhood Hits	85
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LIPB1_HUMAN
θ value	0.21417 (rank : 393)	NC score	0.059647 (rank : 596)
Query Neighborhood Hits	812	Target Neighborhood Hits	640	Shared Neighborhood Hits	65
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

NCOA3_MOUSE
θ value	0.21417 (rank : 394)	NC score	0.029395 (rank : 915)
Query Neighborhood Hits	812	Target Neighborhood Hits	203	Shared Neighborhood Hits	49
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PKHA6_HUMAN
θ value	0.21417 (rank : 395)	NC score	0.049835 (rank : 793)
Query Neighborhood Hits	812	Target Neighborhood Hits	556	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TEX14_HUMAN
θ value	0.21417 (rank : 396)	NC score	0.405842 (rank : 257)
Query Neighborhood Hits	812	Target Neighborhood Hits	1103	Shared Neighborhood Hits	314
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TFE2_HUMAN
θ value	0.21417 (rank : 397)	NC score	0.016705 (rank : 1005)
Query Neighborhood Hits	812	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

TSH2_MOUSE
θ value	0.21417 (rank : 398)	NC score	0.009996 (rank : 1038)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

ZN687_HUMAN
θ value	0.21417 (rank : 399)	NC score	0.018270 (rank : 992)
Query Neighborhood Hits	812	Target Neighborhood Hits	1244	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

BTBDC_HUMAN
θ value	0.279714 (rank : 400)	NC score	0.051243 (rank : 771)
Query Neighborhood Hits	812	Target Neighborhood Hits	248	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CAC1B_MOUSE
θ value	0.279714 (rank : 401)	NC score	0.010782 (rank : 1033)
Query Neighborhood Hits	812	Target Neighborhood Hits	351	Shared Neighborhood Hits	67
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CO4A5_HUMAN
θ value	0.279714 (rank : 402)	NC score	0.059667 (rank : 595)
Query Neighborhood Hits	812	Target Neighborhood Hits	383	Shared Neighborhood Hits	110
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

IRS1_HUMAN
θ value	0.279714 (rank : 403)	NC score	0.023096 (rank : 958)
Query Neighborhood Hits	812	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

ITSN1_HUMAN
θ value	0.279714 (rank : 404)	NC score	0.049261 (rank : 797)
Query Neighborhood Hits	812	Target Neighborhood Hits	1757	Shared Neighborhood Hits	173
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MEFV_MOUSE
θ value	0.279714 (rank : 405)	NC score	0.013275 (rank : 1023)
Query Neighborhood Hits	812	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MYO1E_HUMAN
θ value	0.279714 (rank : 406)	NC score	0.022529 (rank : 961)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	66
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

PAR6A_HUMAN
θ value	0.279714 (rank : 407)	NC score	0.019588 (rank : 980)
Query Neighborhood Hits	812	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PHC2_MOUSE
θ value	0.279714 (rank : 408)	NC score	0.032681 (rank : 890)
Query Neighborhood Hits	812	Target Neighborhood Hits	156	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

SEM6B_MOUSE
θ value	0.279714 (rank : 409)	NC score	0.013807 (rank : 1020)
Query Neighborhood Hits	812	Target Neighborhood Hits	200	Shared Neighborhood Hits	54
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

TRPC6_HUMAN
θ value	0.279714 (rank : 410)	NC score	0.125345 (rank : 311)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

ASTL_HUMAN
θ value	0.365318 (rank : 411)	NC score	0.044885 (rank : 812)
Query Neighborhood Hits	812	Target Neighborhood Hits	252	Shared Neighborhood Hits	77
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

AUXI_HUMAN
θ value	0.365318 (rank : 412)	NC score	0.014490 (rank : 1017)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BCL9_HUMAN
θ value	0.365318 (rank : 413)	NC score	0.099843 (rank : 373)
Query Neighborhood Hits	812	Target Neighborhood Hits	1008	Shared Neighborhood Hits	233
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CITE4_HUMAN
θ value	0.365318 (rank : 414)	NC score	0.064338 (rank : 519)
Query Neighborhood Hits	812	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CO7A1_HUMAN
θ value	0.365318 (rank : 415)	NC score	0.049456 (rank : 795)
Query Neighborhood Hits	812	Target Neighborhood Hits	807	Shared Neighborhood Hits	173
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DIDO1_HUMAN
θ value	0.365318 (rank : 416)	NC score	0.075128 (rank : 453)
Query Neighborhood Hits	812	Target Neighborhood Hits	960	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

JPH2_HUMAN
θ value	0.365318 (rank : 417)	NC score	0.054600 (rank : 714)
Query Neighborhood Hits	812	Target Neighborhood Hits	639	Shared Neighborhood Hits	177
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LIPB1_MOUSE
θ value	0.365318 (rank : 418)	NC score	0.055116 (rank : 700)
Query Neighborhood Hits	812	Target Neighborhood Hits	727	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MILK1_HUMAN
θ value	0.365318 (rank : 419)	NC score	0.059528 (rank : 601)
Query Neighborhood Hits	812	Target Neighborhood Hits	427	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MUC5B_HUMAN
θ value	0.365318 (rank : 420)	NC score	0.063400 (rank : 532)
Query Neighborhood Hits	812	Target Neighborhood Hits	1020	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

OSBP2_HUMAN
θ value	0.365318 (rank : 421)	NC score	0.035418 (rank : 874)
Query Neighborhood Hits	812	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

PAK4_MOUSE
θ value	0.365318 (rank : 422)	NC score	0.040232 (rank : 849)
Query Neighborhood Hits	812	Target Neighborhood Hits	1098	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RERE_HUMAN
θ value	0.365318 (rank : 423)	NC score	0.092864 (rank : 388)
Query Neighborhood Hits	812	Target Neighborhood Hits	779	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RSNL2_HUMAN
θ value	0.365318 (rank : 424)	NC score	0.244717 (rank : 284)
Query Neighborhood Hits	812	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SAM14_HUMAN
θ value	0.365318 (rank : 425)	NC score	0.084409 (rank : 410)
Query Neighborhood Hits	812	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SSBP4_HUMAN
θ value	0.365318 (rank : 426)	NC score	0.060796 (rank : 570)
Query Neighborhood Hits	812	Target Neighborhood Hits	753	Shared Neighborhood Hits	192
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SYN1_HUMAN
θ value	0.365318 (rank : 427)	NC score	0.089071 (rank : 394)
Query Neighborhood Hits	812	Target Neighborhood Hits	419	Shared Neighborhood Hits	151
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TINF2_HUMAN
θ value	0.365318 (rank : 428)	NC score	0.026746 (rank : 936)
Query Neighborhood Hits	812	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

TNR8_HUMAN
θ value	0.365318 (rank : 429)	NC score	0.018111 (rank : 994)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

WIRE_HUMAN
θ value	0.365318 (rank : 430)	NC score	0.109584 (rank : 332)
Query Neighborhood Hits	812	Target Neighborhood Hits	329	Shared Neighborhood Hits	110
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	0.365318 (rank : 431)	NC score	0.114889 (rank : 324)
Query Neighborhood Hits	812	Target Neighborhood Hits	310	Shared Neighborhood Hits	113
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZFHX2_HUMAN
θ value	0.365318 (rank : 432)	NC score	0.016785 (rank : 1003)
Query Neighborhood Hits	812	Target Neighborhood Hits	1178	Shared Neighborhood Hits	118
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ASXL1_HUMAN
θ value	0.47712 (rank : 433)	NC score	0.034032 (rank : 881)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CBLB_HUMAN
θ value	0.47712 (rank : 434)	NC score	0.024199 (rank : 948)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBP_MOUSE
θ value	0.47712 (rank : 435)	NC score	0.084020 (rank : 415)
Query Neighborhood Hits	812	Target Neighborhood Hits	1051	Shared Neighborhood Hits	232
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CEND1_HUMAN
θ value	0.47712 (rank : 436)	NC score	0.087625 (rank : 398)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CENG2_HUMAN
θ value	0.47712 (rank : 437)	NC score	0.340287 (rank : 271)
Query Neighborhood Hits	812	Target Neighborhood Hits	471	Shared Neighborhood Hits	254
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
θ value	0.47712 (rank : 438)	NC score	0.337401 (rank : 273)
Query Neighborhood Hits	812	Target Neighborhood Hits	463	Shared Neighborhood Hits	251
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CIZ1_HUMAN
θ value	0.47712 (rank : 439)	NC score	0.066312 (rank : 504)
Query Neighborhood Hits	812	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CNTRB_MOUSE
θ value	0.47712 (rank : 440)	NC score	0.049044 (rank : 799)
Query Neighborhood Hits	812	Target Neighborhood Hits	1029	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO2A1_MOUSE
θ value	0.47712 (rank : 441)	NC score	0.042344 (rank : 829)
Query Neighborhood Hits	812	Target Neighborhood Hits	483	Shared Neighborhood Hits	122
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO9A1_HUMAN
θ value	0.47712 (rank : 442)	NC score	0.039342 (rank : 857)
Query Neighborhood Hits	812	Target Neighborhood Hits	420	Shared Neighborhood Hits	96
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CONA1_HUMAN
θ value	0.47712 (rank : 443)	NC score	0.035207 (rank : 875)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	82
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

DGKD_HUMAN
θ value	0.47712 (rank : 444)	NC score	0.081720 (rank : 422)
Query Neighborhood Hits	812	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DMRTD_HUMAN
θ value	0.47712 (rank : 445)	NC score	0.060077 (rank : 582)
Query Neighborhood Hits	812	Target Neighborhood Hits	216	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

ERCC5_MOUSE
θ value	0.47712 (rank : 446)	NC score	0.023361 (rank : 956)
Query Neighborhood Hits	812	Target Neighborhood Hits	206	Shared Neighborhood Hits	23
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

GON4L_HUMAN
θ value	0.47712 (rank : 447)	NC score	0.037940 (rank : 864)
Query Neighborhood Hits	812	Target Neighborhood Hits	555	Shared Neighborhood Hits	87
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

NCOA1_HUMAN
θ value	0.47712 (rank : 448)	NC score	0.020858 (rank : 973)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

PHLB1_HUMAN
θ value	0.47712 (rank : 449)	NC score	0.062852 (rank : 540)
Query Neighborhood Hits	812	Target Neighborhood Hits	1038	Shared Neighborhood Hits	165
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

S23IP_MOUSE
θ value	0.47712 (rank : 450)	NC score	0.079112 (rank : 433)
Query Neighborhood Hits	812	Target Neighborhood Hits	363	Shared Neighborhood Hits	110
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

STAM2_HUMAN
θ value	0.47712 (rank : 451)	NC score	0.057505 (rank : 652)
Query Neighborhood Hits	812	Target Neighborhood Hits	288	Shared Neighborhood Hits	66
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

TAU_HUMAN
θ value	0.47712 (rank : 452)	NC score	0.080939 (rank : 427)
Query Neighborhood Hits	812	Target Neighborhood Hits	448	Shared Neighborhood Hits	131
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TF3C1_HUMAN
θ value	0.47712 (rank : 453)	NC score	0.018064 (rank : 995)
Query Neighborhood Hits	812	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

CJ026_MOUSE
θ value	0.62314 (rank : 454)	NC score	0.032400 (rank : 891)
Query Neighborhood Hits	812	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

CMTA1_HUMAN
θ value	0.62314 (rank : 455)	NC score	0.205856 (rank : 292)
Query Neighborhood Hits	812	Target Neighborhood Hits	217	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

COIA1_HUMAN
θ value	0.62314 (rank : 456)	NC score	0.057638 (rank : 649)
Query Neighborhood Hits	812	Target Neighborhood Hits	447	Shared Neighborhood Hits	125
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CUTL1_MOUSE
θ value	0.62314 (rank : 457)	NC score	0.036253 (rank : 871)
Query Neighborhood Hits	812	Target Neighborhood Hits	1620	Shared Neighborhood Hits	143
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

HIC1_MOUSE
θ value	0.62314 (rank : 458)	NC score	-0.008022 (rank : 1101)
Query Neighborhood Hits	812	Target Neighborhood Hits	863	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

K1849_MOUSE
θ value	0.62314 (rank : 459)	NC score	0.018297 (rank : 991)
Query Neighborhood Hits	812	Target Neighborhood Hits	335	Shared Neighborhood Hits	69
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LTB1L_HUMAN
θ value	0.62314 (rank : 460)	NC score	0.039740 (rank : 852)
Query Neighborhood Hits	812	Target Neighborhood Hits	553	Shared Neighborhood Hits	66
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.62314 (rank : 461)	NC score	0.038304 (rank : 862)
Query Neighborhood Hits	812	Target Neighborhood Hits	502	Shared Neighborhood Hits	52
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PER3_HUMAN
θ value	0.62314 (rank : 462)	NC score	0.049247 (rank : 798)
Query Neighborhood Hits	812	Target Neighborhood Hits	479	Shared Neighborhood Hits	121
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RIMB1_HUMAN
θ value	0.62314 (rank : 463)	NC score	0.057629 (rank : 650)
Query Neighborhood Hits	812	Target Neighborhood Hits	1479	Shared Neighborhood Hits	189
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RTN1_HUMAN
θ value	0.62314 (rank : 464)	NC score	0.037851 (rank : 865)
Query Neighborhood Hits	812	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SMRC2_HUMAN
θ value	0.62314 (rank : 465)	NC score	0.041993 (rank : 832)
Query Neighborhood Hits	812	Target Neighborhood Hits	499	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

STAM2_MOUSE
θ value	0.62314 (rank : 466)	NC score	0.059646 (rank : 597)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	61
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ZN509_MOUSE
θ value	0.62314 (rank : 467)	NC score	-0.009954 (rank : 1104)
Query Neighborhood Hits	812	Target Neighborhood Hits	990	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

CBX2_HUMAN
θ value	0.813845 (rank : 468)	NC score	0.043603 (rank : 821)
Query Neighborhood Hits	812	Target Neighborhood Hits	264	Shared Neighborhood Hits	76
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CEND1_MOUSE
θ value	0.813845 (rank : 469)	NC score	0.081867 (rank : 421)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CENG1_HUMAN
θ value	0.813845 (rank : 470)	NC score	0.349902 (rank : 267)
Query Neighborhood Hits	812	Target Neighborhood Hits	544	Shared Neighborhood Hits	291
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CO1A1_MOUSE
θ value	0.813845 (rank : 471)	NC score	0.060976 (rank : 563)
Query Neighborhood Hits	812	Target Neighborhood Hits	457	Shared Neighborhood Hits	132
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

IL4RA_MOUSE
θ value	0.813845 (rank : 472)	NC score	0.041255 (rank : 839)
Query Neighborhood Hits	812	Target Neighborhood Hits	194	Shared Neighborhood Hits	58
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PCQAP_HUMAN
θ value	0.813845 (rank : 473)	NC score	0.069758 (rank : 484)
Query Neighborhood Hits	812	Target Neighborhood Hits	549	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PRB3_HUMAN
θ value	0.813845 (rank : 474)	NC score	0.130713 (rank : 307)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	122
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

RP1L1_HUMAN
θ value	0.813845 (rank : 475)	NC score	0.075575 (rank : 450)
Query Neighborhood Hits	812	Target Neighborhood Hits	1072	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TOPB1_MOUSE
θ value	0.813845 (rank : 476)	NC score	0.020876 (rank : 972)
Query Neighborhood Hits	812	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

TULP4_MOUSE
θ value	0.813845 (rank : 477)	NC score	0.020971 (rank : 969)
Query Neighborhood Hits	812	Target Neighborhood Hits	247	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

WASP_MOUSE
θ value	0.813845 (rank : 478)	NC score	0.070911 (rank : 479)
Query Neighborhood Hits	812	Target Neighborhood Hits	223	Shared Neighborhood Hits	79
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZDHC8_MOUSE
θ value	0.813845 (rank : 479)	NC score	0.039709 (rank : 854)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	77
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ZN628_MOUSE
θ value	0.813845 (rank : 480)	NC score	-0.010565 (rank : 1105)
Query Neighborhood Hits	812	Target Neighborhood Hits	815	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

AMPD2_MOUSE
θ value	1.06291 (rank : 481)	NC score	0.014832 (rank : 1015)
Query Neighborhood Hits	812	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBT5, Q91YI2	Gene names	Ampd2
Domain Architecture	No domain graphic available
Description	AMP deaminase 2 (EC 3.5.4.6).

ANKZ1_HUMAN
θ value	1.06291 (rank : 482)	NC score	0.324503 (rank : 275)
Query Neighborhood Hits	812	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

BAT2_HUMAN
θ value	1.06291 (rank : 483)	NC score	0.119432 (rank : 317)
Query Neighborhood Hits	812	Target Neighborhood Hits	931	Shared Neighborhood Hits	239
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	1.06291 (rank : 484)	NC score	0.105193 (rank : 350)
Query Neighborhood Hits	812	Target Neighborhood Hits	947	Shared Neighborhood Hits	242
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

C1QA_HUMAN
θ value	1.06291 (rank : 485)	NC score	0.018839 (rank : 983)
Query Neighborhood Hits	812	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

CMTA2_MOUSE
θ value	1.06291 (rank : 486)	NC score	0.165759 (rank : 297)
Query Neighborhood Hits	812	Target Neighborhood Hits	216	Shared Neighborhood Hits	117
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

COHA1_MOUSE
θ value	1.06291 (rank : 487)	NC score	0.053908 (rank : 730)
Query Neighborhood Hits	812	Target Neighborhood Hits	414	Shared Neighborhood Hits	119
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DACT1_MOUSE
θ value	1.06291 (rank : 488)	NC score	0.017378 (rank : 998)
Query Neighborhood Hits	812	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

FA61A_MOUSE
θ value	1.06291 (rank : 489)	NC score	0.020236 (rank : 976)
Query Neighborhood Hits	812	Target Neighborhood Hits	81	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

FOG1_HUMAN
θ value	1.06291 (rank : 490)	NC score	0.017878 (rank : 997)
Query Neighborhood Hits	812	Target Neighborhood Hits	981	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOG1_MOUSE
θ value	1.06291 (rank : 491)	NC score	0.021394 (rank : 968)
Query Neighborhood Hits	812	Target Neighborhood Hits	1237	Shared Neighborhood Hits	188
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FREA_HUMAN
θ value	1.06291 (rank : 492)	NC score	0.011625 (rank : 1029)
Query Neighborhood Hits	812	Target Neighborhood Hits	205	Shared Neighborhood Hits	49
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

GA2L1_HUMAN
θ value	1.06291 (rank : 493)	NC score	0.036556 (rank : 867)
Query Neighborhood Hits	812	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GCP60_HUMAN
θ value	1.06291 (rank : 494)	NC score	0.026730 (rank : 937)
Query Neighborhood Hits	812	Target Neighborhood Hits	419	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GRAP2_HUMAN
θ value	1.06291 (rank : 495)	NC score	0.046533 (rank : 807)
Query Neighborhood Hits	812	Target Neighborhood Hits	304	Shared Neighborhood Hits	64
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	1.06291 (rank : 496)	NC score	0.046437 (rank : 809)
Query Neighborhood Hits	812	Target Neighborhood Hits	297	Shared Neighborhood Hits	62
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRIN1_MOUSE
θ value	1.06291 (rank : 497)	NC score	0.084777 (rank : 405)
Query Neighborhood Hits	812	Target Neighborhood Hits	337	Shared Neighborhood Hits	98
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ITSN2_HUMAN
θ value	1.06291 (rank : 498)	NC score	0.041498 (rank : 836)
Query Neighborhood Hits	812	Target Neighborhood Hits	1173	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	1.06291 (rank : 499)	NC score	0.045122 (rank : 810)
Query Neighborhood Hits	812	Target Neighborhood Hits	1371	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ODP2_HUMAN
θ value	1.06291 (rank : 500)	NC score	0.016545 (rank : 1007)
Query Neighborhood Hits	812	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

RAI1_MOUSE
θ value	1.06291 (rank : 501)	NC score	0.044790 (rank : 813)
Query Neighborhood Hits	812	Target Neighborhood Hits	344	Shared Neighborhood Hits	83
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RANB9_HUMAN
θ value	1.06291 (rank : 502)	NC score	0.044886 (rank : 811)
Query Neighborhood Hits	812	Target Neighborhood Hits	179	Shared Neighborhood Hits	74
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RECQ4_HUMAN
θ value	1.06291 (rank : 503)	NC score	0.013146 (rank : 1024)
Query Neighborhood Hits	812	Target Neighborhood Hits	177	Shared Neighborhood Hits	39
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RXRA_HUMAN
θ value	1.06291 (rank : 504)	NC score	0.000082 (rank : 1084)
Query Neighborhood Hits	812	Target Neighborhood Hits	223	Shared Neighborhood Hits	38
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

SMCA2_HUMAN
θ value	1.06291 (rank : 505)	NC score	0.019193 (rank : 982)
Query Neighborhood Hits	812	Target Neighborhood Hits	503	Shared Neighborhood Hits	89
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SRRM2_HUMAN
θ value	1.06291 (rank : 506)	NC score	0.109483 (rank : 334)
Query Neighborhood Hits	812	Target Neighborhood Hits	1296	Shared Neighborhood Hits	230
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYN1_MOUSE
θ value	1.06291 (rank : 507)	NC score	0.084552 (rank : 408)
Query Neighborhood Hits	812	Target Neighborhood Hits	363	Shared Neighborhood Hits	129
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ZBT40_HUMAN
θ value	1.06291 (rank : 508)	NC score	-0.009692 (rank : 1102)
Query Neighborhood Hits	812	Target Neighborhood Hits	949	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

AATK_HUMAN
θ value	1.38821 (rank : 509)	NC score	0.061296 (rank : 560)
Query Neighborhood Hits	812	Target Neighborhood Hits	1243	Shared Neighborhood Hits	193
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ACK1_MOUSE
θ value	1.38821 (rank : 510)	NC score	0.071307 (rank : 475)
Query Neighborhood Hits	812	Target Neighborhood Hits	1080	Shared Neighborhood Hits	165
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ALMS1_HUMAN
θ value	1.38821 (rank : 511)	NC score	0.028532 (rank : 924)
Query Neighborhood Hits	812	Target Neighborhood Hits	356	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

CD2_HUMAN
θ value	1.38821 (rank : 512)	NC score	0.053420 (rank : 741)
Query Neighborhood Hits	812	Target Neighborhood Hits	504	Shared Neighborhood Hits	118
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CENG1_MOUSE
θ value	1.38821 (rank : 513)	NC score	0.352000 (rank : 266)
Query Neighborhood Hits	812	Target Neighborhood Hits	531	Shared Neighborhood Hits	286
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CONA1_MOUSE
θ value	1.38821 (rank : 514)	NC score	0.035598 (rank : 873)
Query Neighborhood Hits	812	Target Neighborhood Hits	254	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

DCC_MOUSE
θ value	1.38821 (rank : 515)	NC score	0.025329 (rank : 942)
Query Neighborhood Hits	812	Target Neighborhood Hits	896	Shared Neighborhood Hits	135
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DLG5_HUMAN
θ value	1.38821 (rank : 516)	NC score	0.029247 (rank : 916)
Query Neighborhood Hits	812	Target Neighborhood Hits	1088	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

EP400_MOUSE
θ value	1.38821 (rank : 517)	NC score	0.040579 (rank : 846)
Query Neighborhood Hits	812	Target Neighborhood Hits	592	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FA61A_HUMAN
θ value	1.38821 (rank : 518)	NC score	0.018490 (rank : 988)
Query Neighborhood Hits	812	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q8ND56, Q76LX7, Q96AR3, Q96K73, Q96SN5, Q9UFR3	Gene names	FAM61A, C19orf13
Domain Architecture	No domain graphic available
Description	Protein FAM61A (Putative alpha synuclein-binding protein) (AlphaSNBP).

GP124_MOUSE
θ value	1.38821 (rank : 519)	NC score	0.007568 (rank : 1053)
Query Neighborhood Hits	812	Target Neighborhood Hits	423	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

K0423_HUMAN
θ value	1.38821 (rank : 520)	NC score	0.024942 (rank : 943)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KCD18_HUMAN
θ value	1.38821 (rank : 521)	NC score	0.015695 (rank : 1013)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

LBXCO_MOUSE
θ value	1.38821 (rank : 522)	NC score	0.021821 (rank : 963)
Query Neighborhood Hits	812	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

LNX2_MOUSE
θ value	1.38821 (rank : 523)	NC score	0.003331 (rank : 1070)
Query Neighborhood Hits	812	Target Neighborhood Hits	407	Shared Neighborhood Hits	22
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

M3K1_MOUSE
θ value	1.38821 (rank : 524)	NC score	0.032365 (rank : 892)
Query Neighborhood Hits	812	Target Neighborhood Hits	952	Shared Neighborhood Hits	78
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MBB1A_HUMAN
θ value	1.38821 (rank : 525)	NC score	0.059539 (rank : 600)
Query Neighborhood Hits	812	Target Neighborhood Hits	665	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MDC1_MOUSE
θ value	1.38821 (rank : 526)	NC score	0.103542 (rank : 361)
Query Neighborhood Hits	812	Target Neighborhood Hits	998	Shared Neighborhood Hits	198
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PDCD7_MOUSE
θ value	1.38821 (rank : 527)	NC score	0.044493 (rank : 816)
Query Neighborhood Hits	812	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PRB4S_HUMAN
θ value	1.38821 (rank : 528)	NC score	0.140747 (rank : 300)
Query Neighborhood Hits	812	Target Neighborhood Hits	330	Shared Neighborhood Hits	128
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PTN23_MOUSE
θ value	1.38821 (rank : 529)	NC score	0.034217 (rank : 879)
Query Neighborhood Hits	812	Target Neighborhood Hits	726	Shared Neighborhood Hits	146
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RAI1_HUMAN
θ value	1.38821 (rank : 530)	NC score	0.041859 (rank : 835)
Query Neighborhood Hits	812	Target Neighborhood Hits	360	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RHG09_HUMAN
θ value	1.38821 (rank : 531)	NC score	0.020511 (rank : 975)
Query Neighborhood Hits	812	Target Neighborhood Hits	186	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SIN3A_MOUSE
θ value	1.38821 (rank : 532)	NC score	0.026888 (rank : 935)
Query Neighborhood Hits	812	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SVIL_MOUSE
θ value	1.38821 (rank : 533)	NC score	0.027938 (rank : 927)
Query Neighborhood Hits	812	Target Neighborhood Hits	439	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

SYNJ1_HUMAN
θ value	1.38821 (rank : 534)	NC score	0.066681 (rank : 498)
Query Neighborhood Hits	812	Target Neighborhood Hits	498	Shared Neighborhood Hits	148
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TRPC1_MOUSE
θ value	1.38821 (rank : 535)	NC score	0.054193 (rank : 722)
Query Neighborhood Hits	812	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TS13_MOUSE
θ value	1.38821 (rank : 536)	NC score	0.043487 (rank : 822)
Query Neighborhood Hits	812	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

APC_HUMAN
θ value	1.81305 (rank : 537)	NC score	0.042462 (rank : 827)
Query Neighborhood Hits	812	Target Neighborhood Hits	603	Shared Neighborhood Hits	98
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ATF2_HUMAN
θ value	1.81305 (rank : 538)	NC score	0.029768 (rank : 912)
Query Neighborhood Hits	812	Target Neighborhood Hits	402	Shared Neighborhood Hits	61
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	1.81305 (rank : 539)	NC score	0.028718 (rank : 921)
Query Neighborhood Hits	812	Target Neighborhood Hits	397	Shared Neighborhood Hits	62
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

BCAR1_HUMAN
θ value	1.81305 (rank : 540)	NC score	0.072423 (rank : 466)
Query Neighborhood Hits	812	Target Neighborhood Hits	554	Shared Neighborhood Hits	152
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CAC1G_HUMAN
θ value	1.81305 (rank : 541)	NC score	0.027018 (rank : 931)
Query Neighborhood Hits	812	Target Neighborhood Hits	587	Shared Neighborhood Hits	148
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CGRE1_HUMAN
θ value	1.81305 (rank : 542)	NC score	0.040941 (rank : 842)
Query Neighborhood Hits	812	Target Neighborhood Hits	354	Shared Neighborhood Hits	66
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CMTA2_HUMAN
θ value	1.81305 (rank : 543)	NC score	0.178384 (rank : 295)
Query Neighborhood Hits	812	Target Neighborhood Hits	199	Shared Neighborhood Hits	123
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CO1A1_HUMAN
θ value	1.81305 (rank : 544)	NC score	0.059200 (rank : 609)
Query Neighborhood Hits	812	Target Neighborhood Hits	475	Shared Neighborhood Hits	133
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COG8_HUMAN
θ value	1.81305 (rank : 545)	NC score	0.020199 (rank : 977)
Query Neighborhood Hits	812	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q96MW5, Q8WVV6, Q9H6F8	Gene names	COG8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

DGKH_HUMAN
θ value	1.81305 (rank : 546)	NC score	0.068076 (rank : 491)
Query Neighborhood Hits	812	Target Neighborhood Hits	255	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

FMN2_HUMAN
θ value	1.81305 (rank : 547)	NC score	0.067678 (rank : 492)
Query Neighborhood Hits	812	Target Neighborhood Hits	484	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GRB2_HUMAN
θ value	1.81305 (rank : 548)	NC score	0.042407 (rank : 828)
Query Neighborhood Hits	812	Target Neighborhood Hits	310	Shared Neighborhood Hits	57
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

IQEC3_MOUSE
θ value	1.81305 (rank : 549)	NC score	0.026634 (rank : 938)
Query Neighborhood Hits	812	Target Neighborhood Hits	274	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IRS2_MOUSE
θ value	1.81305 (rank : 550)	NC score	0.042171 (rank : 830)
Query Neighborhood Hits	812	Target Neighborhood Hits	248	Shared Neighborhood Hits	91
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IWS1_HUMAN
θ value	1.81305 (rank : 551)	NC score	0.055711 (rank : 690)
Query Neighborhood Hits	812	Target Neighborhood Hits	1241	Shared Neighborhood Hits	139
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JIP3_HUMAN
θ value	1.81305 (rank : 552)	NC score	0.039397 (rank : 856)
Query Neighborhood Hits	812	Target Neighborhood Hits	1039	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MARCS_MOUSE
θ value	1.81305 (rank : 553)	NC score	0.079349 (rank : 432)
Query Neighborhood Hits	812	Target Neighborhood Hits	227	Shared Neighborhood Hits	64
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MEF2B_MOUSE
θ value	1.81305 (rank : 554)	NC score	0.031109 (rank : 903)
Query Neighborhood Hits	812	Target Neighborhood Hits	218	Shared Neighborhood Hits	67
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MYO1F_HUMAN
θ value	1.81305 (rank : 555)	NC score	0.024607 (rank : 946)
Query Neighborhood Hits	812	Target Neighborhood Hits	275	Shared Neighborhood Hits	72
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

PER1_HUMAN
θ value	1.81305 (rank : 556)	NC score	0.042034 (rank : 831)
Query Neighborhood Hits	812	Target Neighborhood Hits	215	Shared Neighborhood Hits	69
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER2_MOUSE
θ value	1.81305 (rank : 557)	NC score	0.024764 (rank : 945)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	64
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PUNC_MOUSE
θ value	1.81305 (rank : 558)	NC score	0.005141 (rank : 1063)
Query Neighborhood Hits	812	Target Neighborhood Hits	501	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RHG12_MOUSE
θ value	1.81305 (rank : 559)	NC score	0.015783 (rank : 1012)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SAMN1_HUMAN
θ value	1.81305 (rank : 560)	NC score	0.077000 (rank : 447)
Query Neighborhood Hits	812	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SCAR3_MOUSE
θ value	1.81305 (rank : 561)	NC score	0.032261 (rank : 894)
Query Neighborhood Hits	812	Target Neighborhood Hits	239	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

SLY_MOUSE
θ value	1.81305 (rank : 562)	NC score	0.077629 (rank : 442)
Query Neighborhood Hits	812	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SNIP_HUMAN
θ value	1.81305 (rank : 563)	NC score	0.040227 (rank : 850)
Query Neighborhood Hits	812	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SOCS7_MOUSE
θ value	1.81305 (rank : 564)	NC score	0.024409 (rank : 947)
Query Neighborhood Hits	812	Target Neighborhood Hits	154	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SRBP1_HUMAN
θ value	1.81305 (rank : 565)	NC score	0.037849 (rank : 866)
Query Neighborhood Hits	812	Target Neighborhood Hits	225	Shared Neighborhood Hits	57
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TENS4_MOUSE
θ value	1.81305 (rank : 566)	NC score	0.028300 (rank : 926)
Query Neighborhood Hits	812	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

YBOX2_HUMAN
θ value	1.81305 (rank : 567)	NC score	0.016337 (rank : 1009)
Query Neighborhood Hits	812	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

ZAR1_HUMAN
θ value	1.81305 (rank : 568)	NC score	0.032805 (rank : 889)
Query Neighborhood Hits	812	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZIM10_HUMAN
θ value	1.81305 (rank : 569)	NC score	0.038940 (rank : 859)
Query Neighborhood Hits	812	Target Neighborhood Hits	577	Shared Neighborhood Hits	152
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN219_HUMAN
θ value	1.81305 (rank : 570)	NC score	-0.001998 (rank : 1093)
Query Neighborhood Hits	812	Target Neighborhood Hits	876	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ABTB1_MOUSE
θ value	2.36792 (rank : 571)	NC score	0.283357 (rank : 281)
Query Neighborhood Hits	812	Target Neighborhood Hits	349	Shared Neighborhood Hits	178
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

B4GT1_HUMAN
θ value	2.36792 (rank : 572)	NC score	0.013131 (rank : 1025)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	30
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CABP4_HUMAN
θ value	2.36792 (rank : 573)	NC score	0.001319 (rank : 1075)
Query Neighborhood Hits	812	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CD45_HUMAN
θ value	2.36792 (rank : 574)	NC score	0.003468 (rank : 1069)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	34
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CRKL_HUMAN
θ value	2.36792 (rank : 575)	NC score	0.049470 (rank : 794)
Query Neighborhood Hits	812	Target Neighborhood Hits	313	Shared Neighborhood Hits	65
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	2.36792 (rank : 576)	NC score	0.049003 (rank : 800)
Query Neighborhood Hits	812	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

EPHA3_HUMAN
θ value	2.36792 (rank : 577)	NC score	0.089860 (rank : 391)
Query Neighborhood Hits	812	Target Neighborhood Hits	1005	Shared Neighborhood Hits	77
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

FOXN1_MOUSE
θ value	2.36792 (rank : 578)	NC score	0.014223 (rank : 1018)
Query Neighborhood Hits	812	Target Neighborhood Hits	300	Shared Neighborhood Hits	70
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GNAS1_MOUSE
θ value	2.36792 (rank : 579)	NC score	0.041113 (rank : 841)
Query Neighborhood Hits	812	Target Neighborhood Hits	651	Shared Neighborhood Hits	167
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GR65_HUMAN
θ value	2.36792 (rank : 580)	NC score	0.031310 (rank : 902)
Query Neighborhood Hits	812	Target Neighborhood Hits	148	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

HCN1_MOUSE
θ value	2.36792 (rank : 581)	NC score	0.006974 (rank : 1056)
Query Neighborhood Hits	812	Target Neighborhood Hits	172	Shared Neighborhood Hits	29
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HSF1_MOUSE
θ value	2.36792 (rank : 582)	NC score	0.042882 (rank : 826)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	69
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

LR37A_HUMAN
θ value	2.36792 (rank : 583)	NC score	0.043462 (rank : 823)
Query Neighborhood Hits	812	Target Neighborhood Hits	720	Shared Neighborhood Hits	128
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MACF1_MOUSE
θ value	2.36792 (rank : 584)	NC score	0.014879 (rank : 1014)
Query Neighborhood Hits	812	Target Neighborhood Hits	1313	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MSX3_MOUSE
θ value	2.36792 (rank : 585)	NC score	-0.003651 (rank : 1098)
Query Neighborhood Hits	812	Target Neighborhood Hits	330	Shared Neighborhood Hits	17
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

PDZD2_HUMAN
θ value	2.36792 (rank : 586)	NC score	0.046512 (rank : 808)
Query Neighborhood Hits	812	Target Neighborhood Hits	772	Shared Neighborhood Hits	153
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PRP5_HUMAN
θ value	2.36792 (rank : 587)	NC score	0.090648 (rank : 389)
Query Neighborhood Hits	812	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

RIMB1_MOUSE
θ value	2.36792 (rank : 588)	NC score	0.038727 (rank : 861)
Query Neighborhood Hits	812	Target Neighborhood Hits	1376	Shared Neighborhood Hits	164
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SC24D_HUMAN
θ value	2.36792 (rank : 589)	NC score	0.039721 (rank : 853)
Query Neighborhood Hits	812	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SIX5_HUMAN
θ value	2.36792 (rank : 590)	NC score	0.016762 (rank : 1004)
Query Neighborhood Hits	812	Target Neighborhood Hits	386	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

SNPC4_HUMAN
θ value	2.36792 (rank : 591)	NC score	0.073089 (rank : 463)
Query Neighborhood Hits	812	Target Neighborhood Hits	589	Shared Neighborhood Hits	166
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SRRM2_MOUSE
θ value	2.36792 (rank : 592)	NC score	0.110047 (rank : 328)
Query Neighborhood Hits	812	Target Neighborhood Hits	1470	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYNE1_HUMAN
θ value	2.36792 (rank : 593)	NC score	0.020683 (rank : 974)
Query Neighborhood Hits	812	Target Neighborhood Hits	1484	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TBX6_HUMAN
θ value	2.36792 (rank : 594)	NC score	0.001028 (rank : 1078)
Query Neighborhood Hits	812	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TRPC6_MOUSE
θ value	2.36792 (rank : 595)	NC score	0.097413 (rank : 379)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	92
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TULP4_HUMAN
θ value	2.36792 (rank : 596)	NC score	0.052746 (rank : 750)
Query Neighborhood Hits	812	Target Neighborhood Hits	426	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UB2J1_MOUSE
θ value	2.36792 (rank : 597)	NC score	0.003253 (rank : 1071)
Query Neighborhood Hits	812	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

VGF_HUMAN
θ value	2.36792 (rank : 598)	NC score	0.035111 (rank : 876)
Query Neighborhood Hits	812	Target Neighborhood Hits	167	Shared Neighborhood Hits	34
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

WDR33_HUMAN
θ value	2.36792 (rank : 599)	NC score	0.024171 (rank : 949)
Query Neighborhood Hits	812	Target Neighborhood Hits	638	Shared Neighborhood Hits	108
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

YTHD2_HUMAN
θ value	2.36792 (rank : 600)	NC score	0.012760 (rank : 1027)
Query Neighborhood Hits	812	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

ACK1_HUMAN
θ value	3.0926 (rank : 601)	NC score	0.070226 (rank : 481)
Query Neighborhood Hits	812	Target Neighborhood Hits	1140	Shared Neighborhood Hits	172
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ARI1B_HUMAN
θ value	3.0926 (rank : 602)	NC score	0.054637 (rank : 713)
Query Neighborhood Hits	812	Target Neighborhood Hits	567	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARMX2_MOUSE
θ value	3.0926 (rank : 603)	NC score	0.047796 (rank : 804)
Query Neighborhood Hits	812	Target Neighborhood Hits	349	Shared Neighborhood Hits	96
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ATS19_MOUSE
θ value	3.0926 (rank : 604)	NC score	-0.002931 (rank : 1095)
Query Neighborhood Hits	812	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATX2_MOUSE
θ value	3.0926 (rank : 605)	NC score	0.054906 (rank : 707)
Query Neighborhood Hits	812	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BCL9_MOUSE
θ value	3.0926 (rank : 606)	NC score	0.097366 (rank : 380)
Query Neighborhood Hits	812	Target Neighborhood Hits	770	Shared Neighborhood Hits	200
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BPTF_HUMAN
θ value	3.0926 (rank : 607)	NC score	0.032298 (rank : 893)
Query Neighborhood Hits	812	Target Neighborhood Hits	786	Shared Neighborhood Hits	91
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CCG8_MOUSE
θ value	3.0926 (rank : 608)	NC score	0.004234 (rank : 1067)
Query Neighborhood Hits	812	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHW2	Gene names	Cacng8
Domain Architecture
Description	Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage- gated calcium channel gamma-8 subunit).

CE016_HUMAN
θ value	3.0926 (rank : 609)	NC score	0.016081 (rank : 1011)
Query Neighborhood Hits	812	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

CO2A1_HUMAN
θ value	3.0926 (rank : 610)	NC score	0.043411 (rank : 824)
Query Neighborhood Hits	812	Target Neighborhood Hits	486	Shared Neighborhood Hits	138
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CPSF6_HUMAN
θ value	3.0926 (rank : 611)	NC score	0.085237 (rank : 404)
Query Neighborhood Hits	812	Target Neighborhood Hits	359	Shared Neighborhood Hits	108
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	3.0926 (rank : 612)	NC score	0.086021 (rank : 401)
Query Neighborhood Hits	812	Target Neighborhood Hits	356	Shared Neighborhood Hits	111
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

DLG4_HUMAN
θ value	3.0926 (rank : 613)	NC score	0.008375 (rank : 1043)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	42
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DMRTD_MOUSE
θ value	3.0926 (rank : 614)	NC score	0.018414 (rank : 989)
Query Neighborhood Hits	812	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

EPHA3_MOUSE
θ value	3.0926 (rank : 615)	NC score	0.089635 (rank : 393)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	76
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

FBX42_MOUSE
θ value	3.0926 (rank : 616)	NC score	0.011116 (rank : 1032)
Query Neighborhood Hits	812	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FGFR3_HUMAN
θ value	3.0926 (rank : 617)	NC score	0.049002 (rank : 801)
Query Neighborhood Hits	812	Target Neighborhood Hits	1042	Shared Neighborhood Hits	66
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FREA_MOUSE
θ value	3.0926 (rank : 618)	NC score	0.007568 (rank : 1054)
Query Neighborhood Hits	812	Target Neighborhood Hits	147	Shared Neighborhood Hits	31
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

GRB2_MOUSE
θ value	3.0926 (rank : 619)	NC score	0.041420 (rank : 837)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	57
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HAIR_MOUSE
θ value	3.0926 (rank : 620)	NC score	0.013866 (rank : 1019)
Query Neighborhood Hits	812	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

IF4B_HUMAN
θ value	3.0926 (rank : 621)	NC score	0.027115 (rank : 929)
Query Neighborhood Hits	812	Target Neighborhood Hits	417	Shared Neighborhood Hits	75
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

LBXCO_HUMAN
θ value	3.0926 (rank : 622)	NC score	0.033824 (rank : 884)
Query Neighborhood Hits	812	Target Neighborhood Hits	167	Shared Neighborhood Hits	43
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LRSM1_HUMAN
θ value	3.0926 (rank : 623)	NC score	0.044020 (rank : 819)
Query Neighborhood Hits	812	Target Neighborhood Hits	1078	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LSD1_HUMAN
θ value	3.0926 (rank : 624)	NC score	0.038073 (rank : 863)
Query Neighborhood Hits	812	Target Neighborhood Hits	455	Shared Neighborhood Hits	103
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MACF1_HUMAN
θ value	3.0926 (rank : 625)	NC score	0.018036 (rank : 996)
Query Neighborhood Hits	812	Target Neighborhood Hits	1341	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	3.0926 (rank : 626)	NC score	0.022585 (rank : 960)
Query Neighborhood Hits	812	Target Neighborhood Hits	1321	Shared Neighborhood Hits	94
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MTFR1_MOUSE
θ value	3.0926 (rank : 627)	NC score	0.010255 (rank : 1036)
Query Neighborhood Hits	812	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MB2, Q9CQZ4	Gene names	Mtfr1, Kiaa0009
Domain Architecture	No domain graphic available
Description	Mitochondrial fission regulator 1.

MYST3_HUMAN
θ value	3.0926 (rank : 628)	NC score	0.030570 (rank : 906)
Query Neighborhood Hits	812	Target Neighborhood Hits	772	Shared Neighborhood Hits	104
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NCOA6_MOUSE
θ value	3.0926 (rank : 629)	NC score	0.109993 (rank : 330)
Query Neighborhood Hits	812	Target Neighborhood Hits	1076	Shared Neighborhood Hits	240
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OBSCN_HUMAN
θ value	3.0926 (rank : 630)	NC score	0.029167 (rank : 918)
Query Neighborhood Hits	812	Target Neighborhood Hits	1931	Shared Neighborhood Hits	222
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OST3B_MOUSE
θ value	3.0926 (rank : 631)	NC score	0.001063 (rank : 1077)
Query Neighborhood Hits	812	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

PER2_HUMAN
θ value	3.0926 (rank : 632)	NC score	0.023843 (rank : 953)
Query Neighborhood Hits	812	Target Neighborhood Hits	170	Shared Neighborhood Hits	39
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PF21B_HUMAN
θ value	3.0926 (rank : 633)	NC score	0.026998 (rank : 932)
Query Neighborhood Hits	812	Target Neighborhood Hits	197	Shared Neighborhood Hits	38
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PGCA_HUMAN
θ value	3.0926 (rank : 634)	NC score	0.039489 (rank : 855)
Query Neighborhood Hits	812	Target Neighborhood Hits	821	Shared Neighborhood Hits	121
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PHLPP_HUMAN
θ value	3.0926 (rank : 635)	NC score	0.017329 (rank : 999)
Query Neighborhood Hits	812	Target Neighborhood Hits	604	Shared Neighborhood Hits	101
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PKHG4_HUMAN
θ value	3.0926 (rank : 636)	NC score	0.023867 (rank : 952)
Query Neighborhood Hits	812	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PLRG1_HUMAN
θ value	3.0926 (rank : 637)	NC score	-0.003590 (rank : 1097)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	12
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PSL1_HUMAN
θ value	3.0926 (rank : 638)	NC score	0.054794 (rank : 709)
Query Neighborhood Hits	812	Target Neighborhood Hits	650	Shared Neighborhood Hits	152
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

R3HD1_HUMAN
θ value	3.0926 (rank : 639)	NC score	0.028304 (rank : 925)
Query Neighborhood Hits	812	Target Neighborhood Hits	203	Shared Neighborhood Hits	51
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RP1L1_MOUSE
θ value	3.0926 (rank : 640)	NC score	0.017209 (rank : 1000)
Query Neighborhood Hits	812	Target Neighborhood Hits	170	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SF3B1_HUMAN
θ value	3.0926 (rank : 641)	NC score	0.043919 (rank : 820)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	80
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	3.0926 (rank : 642)	NC score	0.044108 (rank : 818)
Query Neighborhood Hits	812	Target Neighborhood Hits	352	Shared Neighborhood Hits	80
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SFPQ_MOUSE
θ value	3.0926 (rank : 643)	NC score	0.071985 (rank : 473)
Query Neighborhood Hits	812	Target Neighborhood Hits	958	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SOX13_MOUSE
θ value	3.0926 (rank : 644)	NC score	0.021519 (rank : 965)
Query Neighborhood Hits	812	Target Neighborhood Hits	495	Shared Neighborhood Hits	104
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TRPC1_HUMAN
θ value	3.0926 (rank : 645)	NC score	0.058014 (rank : 640)
Query Neighborhood Hits	812	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPV3_HUMAN
θ value	3.0926 (rank : 646)	NC score	0.221272 (rank : 287)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

ULK1_HUMAN
θ value	3.0926 (rank : 647)	NC score	0.040700 (rank : 844)
Query Neighborhood Hits	812	Target Neighborhood Hits	1121	Shared Neighborhood Hits	151
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

YETS2_MOUSE
θ value	3.0926 (rank : 648)	NC score	0.028671 (rank : 923)
Query Neighborhood Hits	812	Target Neighborhood Hits	278	Shared Neighborhood Hits	69
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZYX_HUMAN
θ value	3.0926 (rank : 649)	NC score	0.028883 (rank : 919)
Query Neighborhood Hits	812	Target Neighborhood Hits	387	Shared Neighborhood Hits	80
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

AFF3_HUMAN
θ value	4.03905 (rank : 650)	NC score	0.023587 (rank : 955)
Query Neighborhood Hits	812	Target Neighborhood Hits	190	Shared Neighborhood Hits	48
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

BANK1_MOUSE
θ value	4.03905 (rank : 651)	NC score	0.036241 (rank : 872)
Query Neighborhood Hits	812	Target Neighborhood Hits	63	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

CBP_HUMAN
θ value	4.03905 (rank : 652)	NC score	0.077885 (rank : 440)
Query Neighborhood Hits	812	Target Neighborhood Hits	941	Shared Neighborhood Hits	203
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CNOT4_HUMAN
θ value	4.03905 (rank : 653)	NC score	0.016342 (rank : 1008)
Query Neighborhood Hits	812	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CO1A2_HUMAN
θ value	4.03905 (rank : 654)	NC score	0.040625 (rank : 845)
Query Neighborhood Hits	812	Target Neighborhood Hits	329	Shared Neighborhood Hits	87
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CSTFT_MOUSE
θ value	4.03905 (rank : 655)	NC score	0.018634 (rank : 987)
Query Neighborhood Hits	812	Target Neighborhood Hits	356	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CUTL2_HUMAN
θ value	4.03905 (rank : 656)	NC score	0.033929 (rank : 882)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	124
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DLG1_MOUSE
θ value	4.03905 (rank : 657)	NC score	0.008148 (rank : 1047)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	44
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DTX1_HUMAN
θ value	4.03905 (rank : 658)	NC score	0.016271 (rank : 1010)
Query Neighborhood Hits	812	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

EP400_HUMAN
θ value	4.03905 (rank : 659)	NC score	0.038876 (rank : 860)
Query Neighborhood Hits	812	Target Neighborhood Hits	556	Shared Neighborhood Hits	120
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ETV4_MOUSE
θ value	4.03905 (rank : 660)	NC score	0.003707 (rank : 1068)
Query Neighborhood Hits	812	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

GNDS_HUMAN
θ value	4.03905 (rank : 661)	NC score	0.022385 (rank : 962)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	47
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

HXB2_MOUSE
θ value	4.03905 (rank : 662)	NC score	-0.001048 (rank : 1089)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	28
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

IF4G1_MOUSE
θ value	4.03905 (rank : 663)	NC score	0.047404 (rank : 805)
Query Neighborhood Hits	812	Target Neighborhood Hits	534	Shared Neighborhood Hits	134
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

INP5E_HUMAN
θ value	4.03905 (rank : 664)	NC score	0.032919 (rank : 887)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

ITF2_HUMAN
θ value	4.03905 (rank : 665)	NC score	0.011606 (rank : 1030)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	22
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

JARD2_MOUSE
θ value	4.03905 (rank : 666)	NC score	0.010098 (rank : 1037)
Query Neighborhood Hits	812	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

M3K2_MOUSE
θ value	4.03905 (rank : 667)	NC score	0.030790 (rank : 905)
Query Neighborhood Hits	812	Target Neighborhood Hits	846	Shared Neighborhood Hits	65
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MYBPH_MOUSE
θ value	4.03905 (rank : 668)	NC score	0.009704 (rank : 1040)
Query Neighborhood Hits	812	Target Neighborhood Hits	290	Shared Neighborhood Hits	38
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYCL1_HUMAN
θ value	4.03905 (rank : 669)	NC score	0.010418 (rank : 1035)
Query Neighborhood Hits	812	Target Neighborhood Hits	146	Shared Neighborhood Hits	27
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYO15_MOUSE
θ value	4.03905 (rank : 670)	NC score	0.023804 (rank : 954)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NFAC4_HUMAN
θ value	4.03905 (rank : 671)	NC score	0.018721 (rank : 986)
Query Neighborhood Hits	812	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

NU153_HUMAN
θ value	4.03905 (rank : 672)	NC score	0.024021 (rank : 950)
Query Neighborhood Hits	812	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

NU214_HUMAN
θ value	4.03905 (rank : 673)	NC score	0.079904 (rank : 430)
Query Neighborhood Hits	812	Target Neighborhood Hits	657	Shared Neighborhood Hits	133
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PHF1_HUMAN
θ value	4.03905 (rank : 674)	NC score	0.005360 (rank : 1061)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PO5F1_MOUSE
θ value	4.03905 (rank : 675)	NC score	-0.002113 (rank : 1094)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	15
SwissProt Accessions	P20263, Q63843	Gene names	Pou5f1, Oct-3, Oct-4, Otf-3, Otf3
Domain Architecture
Description	POU domain, class 5, transcription factor 1 (Octamer-binding transcription factor 3) (Oct-3) (Oct-4) (NF-A3).

PRP2_MOUSE
θ value	4.03905 (rank : 676)	NC score	0.138211 (rank : 301)
Query Neighborhood Hits	812	Target Neighborhood Hits	347	Shared Neighborhood Hits	125
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	4.03905 (rank : 677)	NC score	0.117467 (rank : 319)
Query Neighborhood Hits	812	Target Neighborhood Hits	460	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PTN23_HUMAN
θ value	4.03905 (rank : 678)	NC score	0.042923 (rank : 825)
Query Neighborhood Hits	812	Target Neighborhood Hits	646	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RHG12_HUMAN
θ value	4.03905 (rank : 679)	NC score	0.014690 (rank : 1016)
Query Neighborhood Hits	812	Target Neighborhood Hits	190	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RSMN_HUMAN
θ value	4.03905 (rank : 680)	NC score	0.036405 (rank : 868)
Query Neighborhood Hits	812	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	4.03905 (rank : 681)	NC score	0.036405 (rank : 869)
Query Neighborhood Hits	812	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RTN1_MOUSE
θ value	4.03905 (rank : 682)	NC score	0.029220 (rank : 917)
Query Neighborhood Hits	812	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SF3B4_HUMAN
θ value	4.03905 (rank : 683)	NC score	0.032117 (rank : 897)
Query Neighborhood Hits	812	Target Neighborhood Hits	445	Shared Neighborhood Hits	97
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SIN3A_HUMAN
θ value	4.03905 (rank : 684)	NC score	0.025487 (rank : 941)
Query Neighborhood Hits	812	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

TBCD4_MOUSE
θ value	4.03905 (rank : 685)	NC score	0.024807 (rank : 944)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TCGAP_MOUSE
θ value	4.03905 (rank : 686)	NC score	0.059037 (rank : 611)
Query Neighborhood Hits	812	Target Neighborhood Hits	409	Shared Neighborhood Hits	126
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TROAP_HUMAN
θ value	4.03905 (rank : 687)	NC score	0.060901 (rank : 566)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	71
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TRPV1_MOUSE
θ value	4.03905 (rank : 688)	NC score	0.231232 (rank : 286)
Query Neighborhood Hits	812	Target Neighborhood Hits	189	Shared Neighborhood Hits	156
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ZN516_MOUSE
θ value	4.03905 (rank : 689)	NC score	0.010577 (rank : 1034)
Query Neighborhood Hits	812	Target Neighborhood Hits	1197	Shared Neighborhood Hits	175
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZXDB_HUMAN
θ value	4.03905 (rank : 690)	NC score	-0.011060 (rank : 1106)
Query Neighborhood Hits	812	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	P98169, Q9UBB3	Gene names	ZXDB
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDB.

ABI2_HUMAN
θ value	5.27518 (rank : 691)	NC score	0.054687 (rank : 711)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ACRO_HUMAN
θ value	5.27518 (rank : 692)	NC score	-0.001486 (rank : 1091)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	48
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ARI1A_HUMAN
θ value	5.27518 (rank : 693)	NC score	0.077791 (rank : 441)
Query Neighborhood Hits	812	Target Neighborhood Hits	787	Shared Neighborhood Hits	194
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAT3_HUMAN
θ value	5.27518 (rank : 694)	NC score	0.069250 (rank : 486)
Query Neighborhood Hits	812	Target Neighborhood Hits	490	Shared Neighborhood Hits	149
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BCAR1_MOUSE
θ value	5.27518 (rank : 695)	NC score	0.065981 (rank : 506)
Query Neighborhood Hits	812	Target Neighborhood Hits	438	Shared Neighborhood Hits	137
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CNOT4_MOUSE
θ value	5.27518 (rank : 696)	NC score	0.023883 (rank : 951)
Query Neighborhood Hits	812	Target Neighborhood Hits	277	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

DHX37_HUMAN
θ value	5.27518 (rank : 697)	NC score	0.008007 (rank : 1049)
Query Neighborhood Hits	812	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DTX1_MOUSE
θ value	5.27518 (rank : 698)	NC score	0.021451 (rank : 967)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

EFS_HUMAN
θ value	5.27518 (rank : 699)	NC score	0.051438 (rank : 769)
Query Neighborhood Hits	812	Target Neighborhood Hits	348	Shared Neighborhood Hits	102
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EGR4_HUMAN
θ value	5.27518 (rank : 700)	NC score	-0.005751 (rank : 1099)
Query Neighborhood Hits	812	Target Neighborhood Hits	939	Shared Neighborhood Hits	87
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

ERBB2_MOUSE
θ value	5.27518 (rank : 701)	NC score	0.060289 (rank : 578)
Query Neighborhood Hits	812	Target Neighborhood Hits	918	Shared Neighborhood Hits	72
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FOXGA_HUMAN
θ value	5.27518 (rank : 702)	NC score	0.000909 (rank : 1080)
Query Neighborhood Hits	812	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

FRS3_HUMAN
θ value	5.27518 (rank : 703)	NC score	0.020958 (rank : 970)
Query Neighborhood Hits	812	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

GAK_HUMAN
θ value	5.27518 (rank : 704)	NC score	0.031433 (rank : 901)
Query Neighborhood Hits	812	Target Neighborhood Hits	1028	Shared Neighborhood Hits	116
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

K1802_HUMAN
θ value	5.27518 (rank : 705)	NC score	0.060345 (rank : 577)
Query Neighborhood Hits	812	Target Neighborhood Hits	1378	Shared Neighborhood Hits	202
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNC3_MOUSE
θ value	5.27518 (rank : 706)	NC score	-0.001393 (rank : 1090)
Query Neighborhood Hits	812	Target Neighborhood Hits	173	Shared Neighborhood Hits	19
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KIF1C_MOUSE
θ value	5.27518 (rank : 707)	NC score	-0.000616 (rank : 1085)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIFC3_HUMAN
θ value	5.27518 (rank : 708)	NC score	0.007915 (rank : 1050)
Query Neighborhood Hits	812	Target Neighborhood Hits	619	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

LRC56_HUMAN
θ value	5.27518 (rank : 709)	NC score	0.019714 (rank : 979)
Query Neighborhood Hits	812	Target Neighborhood Hits	165	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MAML1_MOUSE
θ value	5.27518 (rank : 710)	NC score	0.032223 (rank : 895)
Query Neighborhood Hits	812	Target Neighborhood Hits	279	Shared Neighborhood Hits	84
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MILK1_MOUSE
θ value	5.27518 (rank : 711)	NC score	0.068672 (rank : 487)
Query Neighborhood Hits	812	Target Neighborhood Hits	788	Shared Neighborhood Hits	193
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINK1_MOUSE
θ value	5.27518 (rank : 712)	NC score	0.032155 (rank : 896)
Query Neighborhood Hits	812	Target Neighborhood Hits	1451	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MUC13_MOUSE
θ value	5.27518 (rank : 713)	NC score	0.081160 (rank : 425)
Query Neighborhood Hits	812	Target Neighborhood Hits	447	Shared Neighborhood Hits	95
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PAR6A_MOUSE
θ value	5.27518 (rank : 714)	NC score	0.008206 (rank : 1045)
Query Neighborhood Hits	812	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PCLO_HUMAN
θ value	5.27518 (rank : 715)	NC score	0.103149 (rank : 364)
Query Neighborhood Hits	812	Target Neighborhood Hits	2046	Shared Neighborhood Hits	316
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PDC6I_MOUSE
θ value	5.27518 (rank : 716)	NC score	0.048380 (rank : 802)
Query Neighborhood Hits	812	Target Neighborhood Hits	275	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDLI5_HUMAN
θ value	5.27518 (rank : 717)	NC score	0.007565 (rank : 1055)
Query Neighborhood Hits	812	Target Neighborhood Hits	322	Shared Neighborhood Hits	43
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PRDM4_HUMAN
θ value	5.27518 (rank : 718)	NC score	-0.012388 (rank : 1109)
Query Neighborhood Hits	812	Target Neighborhood Hits	749	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UKN5, Q9UFA6	Gene names	PRDM4, PFM1
Domain Architecture
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).

RBNS5_HUMAN
θ value	5.27518 (rank : 719)	NC score	0.018362 (rank : 990)
Query Neighborhood Hits	812	Target Neighborhood Hits	242	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

SPRE3_MOUSE
θ value	5.27518 (rank : 720)	NC score	0.019855 (rank : 978)
Query Neighborhood Hits	812	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SYT3_HUMAN
θ value	5.27518 (rank : 721)	NC score	0.001128 (rank : 1076)
Query Neighborhood Hits	812	Target Neighborhood Hits	145	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

TAF1C_MOUSE
θ value	5.27518 (rank : 722)	NC score	0.009786 (rank : 1039)
Query Neighborhood Hits	812	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

TCOF_HUMAN
θ value	5.27518 (rank : 723)	NC score	0.082274 (rank : 420)
Query Neighborhood Hits	812	Target Neighborhood Hits	543	Shared Neighborhood Hits	118
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TM131_MOUSE
θ value	5.27518 (rank : 724)	NC score	0.031667 (rank : 900)
Query Neighborhood Hits	812	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

TRAK2_HUMAN
θ value	5.27518 (rank : 725)	NC score	0.029469 (rank : 914)
Query Neighborhood Hits	812	Target Neighborhood Hits	476	Shared Neighborhood Hits	44
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TSH2_HUMAN
θ value	5.27518 (rank : 726)	NC score	0.008134 (rank : 1048)
Query Neighborhood Hits	812	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

TTC28_HUMAN
θ value	5.27518 (rank : 727)	NC score	0.018799 (rank : 984)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	45
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

WASIP_HUMAN
θ value	5.27518 (rank : 728)	NC score	0.142472 (rank : 299)
Query Neighborhood Hits	812	Target Neighborhood Hits	458	Shared Neighborhood Hits	153
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	5.27518 (rank : 729)	NC score	0.125921 (rank : 310)
Query Neighborhood Hits	812	Target Neighborhood Hits	392	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

YTHD1_HUMAN
θ value	5.27518 (rank : 730)	NC score	0.013479 (rank : 1021)
Query Neighborhood Hits	812	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

ARHG2_HUMAN
θ value	6.88961 (rank : 731)	NC score	0.007854 (rank : 1051)
Query Neighborhood Hits	812	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

AUTS2_HUMAN
θ value	6.88961 (rank : 732)	NC score	0.041374 (rank : 838)
Query Neighborhood Hits	812	Target Neighborhood Hits	342	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAT3_MOUSE
θ value	6.88961 (rank : 733)	NC score	0.072090 (rank : 471)
Query Neighborhood Hits	812	Target Neighborhood Hits	518	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAZ2A_MOUSE
θ value	6.88961 (rank : 734)	NC score	0.041913 (rank : 834)
Query Neighborhood Hits	812	Target Neighborhood Hits	744	Shared Neighborhood Hits	149
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BIN1_HUMAN
θ value	6.88961 (rank : 735)	NC score	0.047931 (rank : 803)
Query Neighborhood Hits	812	Target Neighborhood Hits	335	Shared Neighborhood Hits	95
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CIC_HUMAN
θ value	6.88961 (rank : 736)	NC score	0.078830 (rank : 435)
Query Neighborhood Hits	812	Target Neighborhood Hits	992	Shared Neighborhood Hits	241
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO4A1_MOUSE
θ value	6.88961 (rank : 737)	NC score	0.040553 (rank : 847)
Query Neighborhood Hits	812	Target Neighborhood Hits	450	Shared Neighborhood Hits	121
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CT032_HUMAN
θ value	6.88961 (rank : 738)	NC score	0.058540 (rank : 626)
Query Neighborhood Hits	812	Target Neighborhood Hits	235	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DNM3A_MOUSE
θ value	6.88961 (rank : 739)	NC score	0.009648 (rank : 1042)
Query Neighborhood Hits	812	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

FBX18_MOUSE
θ value	6.88961 (rank : 740)	NC score	0.004916 (rank : 1065)
Query Neighborhood Hits	812	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2I9, Q8C444, Q99KS0, Q9CTC6, Q9QZG7	Gene names	Fbxo18, Fbh1, Fbx18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

GAB2_MOUSE
θ value	6.88961 (rank : 741)	NC score	0.016583 (rank : 1006)
Query Neighborhood Hits	812	Target Neighborhood Hits	220	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GLI1_HUMAN
θ value	6.88961 (rank : 742)	NC score	-0.007341 (rank : 1100)
Query Neighborhood Hits	812	Target Neighborhood Hits	828	Shared Neighborhood Hits	64
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HRSL5_HUMAN
θ value	6.88961 (rank : 743)	NC score	0.006395 (rank : 1057)
Query Neighborhood Hits	812	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

HXA5_HUMAN
θ value	6.88961 (rank : 744)	NC score	-0.003002 (rank : 1096)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	18
SwissProt Accessions	P20719, O43367, Q96CY6	Gene names	HOXA5, HOX1C
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1C).

IF4B_MOUSE
θ value	6.88961 (rank : 745)	NC score	0.027832 (rank : 928)
Query Neighborhood Hits	812	Target Neighborhood Hits	368	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

K0310_HUMAN
θ value	6.88961 (rank : 746)	NC score	0.061152 (rank : 561)
Query Neighborhood Hits	812	Target Neighborhood Hits	420	Shared Neighborhood Hits	126
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAST3_HUMAN
θ value	6.88961 (rank : 747)	NC score	0.030149 (rank : 910)
Query Neighborhood Hits	812	Target Neighborhood Hits	1128	Shared Neighborhood Hits	129
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MTSS1_MOUSE
θ value	6.88961 (rank : 748)	NC score	0.053903 (rank : 731)
Query Neighborhood Hits	812	Target Neighborhood Hits	592	Shared Neighborhood Hits	154
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NAL10_HUMAN
θ value	6.88961 (rank : 749)	NC score	0.000533 (rank : 1082)
Query Neighborhood Hits	812	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NOS1_MOUSE
θ value	6.88961 (rank : 750)	NC score	0.001442 (rank : 1074)
Query Neighborhood Hits	812	Target Neighborhood Hits	155	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

OBF1_HUMAN
θ value	6.88961 (rank : 751)	NC score	0.032915 (rank : 888)
Query Neighborhood Hits	812	Target Neighborhood Hits	203	Shared Neighborhood Hits	59
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PF21B_MOUSE
θ value	6.88961 (rank : 752)	NC score	0.026956 (rank : 933)
Query Neighborhood Hits	812	Target Neighborhood Hits	278	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PRP1_HUMAN
θ value	6.88961 (rank : 753)	NC score	0.148758 (rank : 298)
Query Neighborhood Hits	812	Target Neighborhood Hits	385	Shared Neighborhood Hits	137
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RFIP1_HUMAN
θ value	6.88961 (rank : 754)	NC score	0.039198 (rank : 858)
Query Neighborhood Hits	812	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP1_MOUSE
θ value	6.88961 (rank : 755)	NC score	0.019348 (rank : 981)
Query Neighborhood Hits	812	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP4_HUMAN
θ value	6.88961 (rank : 756)	NC score	0.023343 (rank : 957)
Query Neighborhood Hits	812	Target Neighborhood Hits	785	Shared Neighborhood Hits	59
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RSMB_HUMAN
θ value	6.88961 (rank : 757)	NC score	0.031022 (rank : 904)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

SOS1_HUMAN
θ value	6.88961 (rank : 758)	NC score	0.017003 (rank : 1002)
Query Neighborhood Hits	812	Target Neighborhood Hits	274	Shared Neighborhood Hits	52
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	6.88961 (rank : 759)	NC score	0.021679 (rank : 964)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	54
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SRBS1_HUMAN
θ value	6.88961 (rank : 760)	NC score	0.040477 (rank : 848)
Query Neighborhood Hits	812	Target Neighborhood Hits	396	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYNJ1_MOUSE
θ value	6.88961 (rank : 761)	NC score	0.058961 (rank : 613)
Query Neighborhood Hits	812	Target Neighborhood Hits	516	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T240L_HUMAN
θ value	6.88961 (rank : 762)	NC score	0.013439 (rank : 1022)
Query Neighborhood Hits	812	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TAF6_MOUSE
θ value	6.88961 (rank : 763)	NC score	0.029746 (rank : 913)
Query Neighborhood Hits	812	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

TMG3_MOUSE
θ value	6.88961 (rank : 764)	NC score	0.002214 (rank : 1072)
Query Neighborhood Hits	812	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

WASF2_MOUSE
θ value	6.88961 (rank : 765)	NC score	0.057949 (rank : 643)
Query Neighborhood Hits	812	Target Neighborhood Hits	315	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ZN185_HUMAN
θ value	6.88961 (rank : 766)	NC score	0.012383 (rank : 1028)
Query Neighborhood Hits	812	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

ARAF_HUMAN
θ value	8.99809 (rank : 767)	NC score	0.053268 (rank : 743)
Query Neighborhood Hits	812	Target Neighborhood Hits	924	Shared Neighborhood Hits	82
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

BRSK2_HUMAN
θ value	8.99809 (rank : 768)	NC score	0.028759 (rank : 920)
Query Neighborhood Hits	812	Target Neighborhood Hits	897	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

C1QR1_HUMAN
θ value	8.99809 (rank : 769)	NC score	0.031691 (rank : 899)
Query Neighborhood Hits	812	Target Neighborhood Hits	493	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CD2AP_MOUSE
θ value	8.99809 (rank : 770)	NC score	0.055035 (rank : 702)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CMGA_MOUSE
θ value	8.99809 (rank : 771)	NC score	0.026099 (rank : 939)
Query Neighborhood Hits	812	Target Neighborhood Hits	172	Shared Neighborhood Hits	31
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

CN032_HUMAN
θ value	8.99809 (rank : 772)	NC score	0.085409 (rank : 403)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CO5A3_HUMAN
θ value	8.99809 (rank : 773)	NC score	0.033450 (rank : 885)
Query Neighborhood Hits	812	Target Neighborhood Hits	433	Shared Neighborhood Hits	115
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO9A2_HUMAN
θ value	8.99809 (rank : 774)	NC score	0.030550 (rank : 907)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	65
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COJA1_HUMAN
θ value	8.99809 (rank : 775)	NC score	0.034735 (rank : 878)
Query Neighborhood Hits	812	Target Neighborhood Hits	323	Shared Neighborhood Hits	82
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

COT2_HUMAN
θ value	8.99809 (rank : 776)	NC score	-0.000667 (rank : 1086)
Query Neighborhood Hits	812	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	8.99809 (rank : 777)	NC score	-0.000667 (rank : 1087)
Query Neighborhood Hits	812	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

CRTC1_HUMAN
θ value	8.99809 (rank : 778)	NC score	0.059735 (rank : 590)
Query Neighborhood Hits	812	Target Neighborhood Hits	319	Shared Neighborhood Hits	114
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS007_MOUSE
θ value	8.99809 (rank : 779)	NC score	0.073921 (rank : 459)
Query Neighborhood Hits	812	Target Neighborhood Hits	464	Shared Neighborhood Hits	122
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DEN1A_MOUSE
θ value	8.99809 (rank : 780)	NC score	0.027081 (rank : 930)
Query Neighborhood Hits	812	Target Neighborhood Hits	178	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DNMT1_HUMAN
θ value	8.99809 (rank : 781)	NC score	0.026934 (rank : 934)
Query Neighborhood Hits	812	Target Neighborhood Hits	401	Shared Neighborhood Hits	45
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

ESPL1_MOUSE
θ value	8.99809 (rank : 782)	NC score	0.006200 (rank : 1058)
Query Neighborhood Hits	812	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

FETUB_MOUSE
θ value	8.99809 (rank : 783)	NC score	0.004261 (rank : 1066)
Query Neighborhood Hits	812	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

FHOD1_HUMAN
θ value	8.99809 (rank : 784)	NC score	0.018796 (rank : 985)
Query Neighborhood Hits	812	Target Neighborhood Hits	184	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FOXE3_MOUSE
θ value	8.99809 (rank : 785)	NC score	0.000732 (rank : 1081)
Query Neighborhood Hits	812	Target Neighborhood Hits	118	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QY14	Gene names	Foxe3
Domain Architecture
Description	Forkhead box protein E3.

GLUD1_MOUSE
θ value	8.99809 (rank : 786)	NC score	0.008317 (rank : 1044)
Query Neighborhood Hits	812	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

GP156_HUMAN
θ value	8.99809 (rank : 787)	NC score	0.009697 (rank : 1041)
Query Neighborhood Hits	812	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

HCN2_HUMAN
θ value	8.99809 (rank : 788)	NC score	0.029863 (rank : 911)
Query Neighborhood Hits	812	Target Neighborhood Hits	369	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCNQ1_HUMAN
θ value	8.99809 (rank : 789)	NC score	-0.001886 (rank : 1092)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

LRSM1_MOUSE
θ value	8.99809 (rank : 790)	NC score	0.040140 (rank : 851)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	57
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

LTB1L_MOUSE
θ value	8.99809 (rank : 791)	NC score	0.034138 (rank : 880)
Query Neighborhood Hits	812	Target Neighborhood Hits	514	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	8.99809 (rank : 792)	NC score	0.033923 (rank : 883)
Query Neighborhood Hits	812	Target Neighborhood Hits	479	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MBD6_HUMAN
θ value	8.99809 (rank : 793)	NC score	0.107110 (rank : 339)
Query Neighborhood Hits	812	Target Neighborhood Hits	349	Shared Neighborhood Hits	122
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MINT_HUMAN
θ value	8.99809 (rank : 794)	NC score	0.054960 (rank : 705)
Query Neighborhood Hits	812	Target Neighborhood Hits	1291	Shared Neighborhood Hits	177
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST1_HUMAN
θ value	8.99809 (rank : 795)	NC score	0.002155 (rank : 1073)
Query Neighborhood Hits	812	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

NAGS_HUMAN
θ value	8.99809 (rank : 796)	NC score	0.004952 (rank : 1064)
Query Neighborhood Hits	812	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N159, Q8IWR4	Gene names	NAGS
Domain Architecture	No domain graphic available
Description	N-acetylglutamate synthase, mitochondrial precursor (EC 2.3.1.1) (Amino-acid acetyltransferase) [Contains: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form].

PO6F2_MOUSE
θ value	8.99809 (rank : 797)	NC score	0.022862 (rank : 959)
Query Neighborhood Hits	812	Target Neighborhood Hits	639	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RAPH1_HUMAN
θ value	8.99809 (rank : 798)	NC score	0.084518 (rank : 409)
Query Neighborhood Hits	812	Target Neighborhood Hits	593	Shared Neighborhood Hits	163
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RAVR1_MOUSE
θ value	8.99809 (rank : 799)	NC score	0.008161 (rank : 1046)
Query Neighborhood Hits	812	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

RSNL2_MOUSE
θ value	8.99809 (rank : 800)	NC score	0.201648 (rank : 294)
Query Neighborhood Hits	812	Target Neighborhood Hits	129	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SAMN1_MOUSE
θ value	8.99809 (rank : 801)	NC score	0.075298 (rank : 451)
Query Neighborhood Hits	812	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

SAPS1_HUMAN
θ value	8.99809 (rank : 802)	NC score	0.064536 (rank : 515)
Query Neighborhood Hits	812	Target Neighborhood Hits	704	Shared Neighborhood Hits	185
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SFPQ_HUMAN
θ value	8.99809 (rank : 803)	NC score	0.066292 (rank : 505)
Query Neighborhood Hits	812	Target Neighborhood Hits	986	Shared Neighborhood Hits	184
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SH3K1_HUMAN
θ value	8.99809 (rank : 804)	NC score	0.059992 (rank : 584)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	82
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	8.99809 (rank : 805)	NC score	0.059117 (rank : 610)
Query Neighborhood Hits	812	Target Neighborhood Hits	332	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

STAC3_HUMAN
θ value	8.99809 (rank : 806)	NC score	0.044548 (rank : 815)
Query Neighborhood Hits	812	Target Neighborhood Hits	228	Shared Neighborhood Hits	49
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	8.99809 (rank : 807)	NC score	0.044264 (rank : 817)
Query Neighborhood Hits	812	Target Neighborhood Hits	232	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

TENX_HUMAN
θ value	8.99809 (rank : 808)	NC score	0.041964 (rank : 833)
Query Neighborhood Hits	812	Target Neighborhood Hits	789	Shared Neighborhood Hits	87
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TM108_HUMAN
θ value	8.99809 (rank : 809)	NC score	0.057895 (rank : 645)
Query Neighborhood Hits	812	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TRI25_MOUSE
θ value	8.99809 (rank : 810)	NC score	0.001021 (rank : 1079)
Query Neighborhood Hits	812	Target Neighborhood Hits	446	Shared Neighborhood Hits	19
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

ZN579_HUMAN
θ value	8.99809 (rank : 811)	NC score	-0.012000 (rank : 1108)
Query Neighborhood Hits	812	Target Neighborhood Hits	726	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NAF0	Gene names	ZNF579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

ZN580_MOUSE
θ value	8.99809 (rank : 812)	NC score	-0.011829 (rank : 1107)
Query Neighborhood Hits	812	Target Neighborhood Hits	711	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

3BP1_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.059269 (rank : 605)
Query Neighborhood Hits	812	Target Neighborhood Hits	376	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AATK_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.058730 (rank : 620)
Query Neighborhood Hits	812	Target Neighborhood Hits	942	Shared Neighborhood Hits	116
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABL1_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.063167 (rank : 535)
Query Neighborhood Hits	812	Target Neighborhood Hits	1220	Shared Neighborhood Hits	159
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 816)	NC score	0.064255 (rank : 521)
Query Neighborhood Hits	812	Target Neighborhood Hits	1178	Shared Neighborhood Hits	158
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.058543 (rank : 625)
Query Neighborhood Hits	812	Target Neighborhood Hits	1045	Shared Neighborhood Hits	107
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABTB1_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.239047 (rank : 285)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

AFF1_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.063105 (rank : 536)
Query Neighborhood Hits	812	Target Neighborhood Hits	506	Shared Neighborhood Hits	110
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF1_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.050815 (rank : 781)
Query Neighborhood Hits	812	Target Neighborhood Hits	351	Shared Neighborhood Hits	90
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALEX_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.077945 (rank : 439)
Query Neighborhood Hits	812	Target Neighborhood Hits	361	Shared Neighborhood Hits	101
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALK_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.056193 (rank : 682)
Query Neighborhood Hits	812	Target Neighborhood Hits	795	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.056987 (rank : 660)
Query Neighborhood Hits	812	Target Neighborhood Hits	811	Shared Neighborhood Hits	69
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AN13D_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.050651 (rank : 784)
Query Neighborhood Hits	812	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

AN13D_MOUSE
θ value	θ > 10 (rank : 825)	NC score	0.051015 (rank : 778)
Query Neighborhood Hits	812	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ANKF1_HUMAN
θ value	θ > 10 (rank : 826)	NC score	0.126931 (rank : 309)
Query Neighborhood Hits	812	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.205398 (rank : 293)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.255797 (rank : 282)
Query Neighborhood Hits	812	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANPRA_MOUSE
θ value	θ > 10 (rank : 829)	NC score	0.051077 (rank : 775)
Query Neighborhood Hits	812	Target Neighborhood Hits	600	Shared Neighborhood Hits	57
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 830)	NC score	0.052089 (rank : 758)
Query Neighborhood Hits	812	Target Neighborhood Hits	646	Shared Neighborhood Hits	56
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 831)	NC score	0.053265 (rank : 744)
Query Neighborhood Hits	812	Target Neighborhood Hits	607	Shared Neighborhood Hits	54
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ARAF_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.052331 (rank : 754)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	69
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ARFG1_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.053318 (rank : 742)
Query Neighborhood Hits	812	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 834)	NC score	0.053937 (rank : 728)
Query Neighborhood Hits	812	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.053478 (rank : 739)
Query Neighborhood Hits	812	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.053644 (rank : 734)
Query Neighborhood Hits	812	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ATN1_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.104739 (rank : 352)
Query Neighborhood Hits	812	Target Neighborhood Hits	676	Shared Neighborhood Hits	149
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.056354 (rank : 678)
Query Neighborhood Hits	812	Target Neighborhood Hits	443	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BAG3_MOUSE
θ value	θ > 10 (rank : 839)	NC score	0.065691 (rank : 507)
Query Neighborhood Hits	812	Target Neighborhood Hits	513	Shared Neighborhood Hits	144
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.085740 (rank : 402)
Query Neighborhood Hits	812	Target Neighborhood Hits	321	Shared Neighborhood Hits	75
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.102410 (rank : 366)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT4_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.218944 (rank : 288)
Query Neighborhood Hits	812	Target Neighborhood Hits	157	Shared Neighborhood Hits	114
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.249738 (rank : 283)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BLK_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.059914 (rank : 585)
Query Neighborhood Hits	812	Target Neighborhood Hits	994	Shared Neighborhood Hits	103
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.058920 (rank : 614)
Query Neighborhood Hits	812	Target Neighborhood Hits	992	Shared Neighborhood Hits	98
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMX_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.055998 (rank : 685)
Query Neighborhood Hits	812	Target Neighborhood Hits	942	Shared Neighborhood Hits	78
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.056354 (rank : 679)
Query Neighborhood Hits	812	Target Neighborhood Hits	912	Shared Neighborhood Hits	75
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.054498 (rank : 715)
Query Neighborhood Hits	812	Target Neighborhood Hits	883	Shared Neighborhood Hits	71
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRD4_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.051513 (rank : 764)
Query Neighborhood Hits	812	Target Neighborhood Hits	845	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTK_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.062361 (rank : 544)
Query Neighborhood Hits	812	Target Neighborhood Hits	1026	Shared Neighborhood Hits	111
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.061842 (rank : 549)
Query Neighborhood Hits	812	Target Neighborhood Hits	1017	Shared Neighborhood Hits	108
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CABIN_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.072948 (rank : 464)
Query Neighborhood Hits	812	Target Neighborhood Hits	490	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCNK_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.058202 (rank : 635)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	95
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2AP_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.053461 (rank : 740)
Query Neighborhood Hits	812	Target Neighborhood Hits	315	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CDN1C_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.062029 (rank : 547)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	59
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CEL_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.057823 (rank : 647)
Query Neighborhood Hits	812	Target Neighborhood Hits	896	Shared Neighborhood Hits	199
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CENA1_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.056953 (rank : 662)
Query Neighborhood Hits	812	Target Neighborhood Hits	87	Shared Neighborhood Hits	26
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.052042 (rank : 759)
Query Neighborhood Hits	812	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 859)	NC score	0.052907 (rank : 749)
Query Neighborhood Hits	812	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND2_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.057411 (rank : 653)
Query Neighborhood Hits	812	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CIC_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.063671 (rank : 527)
Query Neighborhood Hits	812	Target Neighborhood Hits	742	Shared Neighborhood Hits	192
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ078_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.074897 (rank : 456)
Query Neighborhood Hits	812	Target Neighborhood Hits	559	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.078441 (rank : 436)
Query Neighborhood Hits	812	Target Neighborhood Hits	408	Shared Neighborhood Hits	107
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.082290 (rank : 419)
Query Neighborhood Hits	812	Target Neighborhood Hits	233	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.092987 (rank : 387)
Query Neighborhood Hits	812	Target Neighborhood Hits	385	Shared Neighborhood Hits	98
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNOT3_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.055276 (rank : 696)
Query Neighborhood Hits	812	Target Neighborhood Hits	425	Shared Neighborhood Hits	97
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.055438 (rank : 693)
Query Neighborhood Hits	812	Target Neighborhood Hits	504	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO039_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.051688 (rank : 762)
Query Neighborhood Hits	812	Target Neighborhood Hits	445	Shared Neighborhood Hits	122
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CO3A1_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.059456 (rank : 603)
Query Neighborhood Hits	812	Target Neighborhood Hits	452	Shared Neighborhood Hits	126
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.059743 (rank : 589)
Query Neighborhood Hits	812	Target Neighborhood Hits	466	Shared Neighborhood Hits	134
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COHA1_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.055128 (rank : 699)
Query Neighborhood Hits	812	Target Neighborhood Hits	400	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CS007_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.058752 (rank : 617)
Query Neighborhood Hits	812	Target Neighborhood Hits	401	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS016_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.077063 (rank : 446)
Query Neighborhood Hits	812	Target Neighborhood Hits	310	Shared Neighborhood Hits	99
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSK_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.057823 (rank : 646)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 875)	NC score	0.056706 (rank : 665)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CTDP1_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.066718 (rank : 497)
Query Neighborhood Hits	812	Target Neighborhood Hits	416	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

CU081_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.084361 (rank : 411)
Query Neighborhood Hits	812	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DDR1_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.059253 (rank : 606)
Query Neighborhood Hits	812	Target Neighborhood Hits	819	Shared Neighborhood Hits	64
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.059223 (rank : 607)
Query Neighborhood Hits	812	Target Neighborhood Hits	818	Shared Neighborhood Hits	64
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.057321 (rank : 654)
Query Neighborhood Hits	812	Target Neighborhood Hits	818	Shared Neighborhood Hits	62
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 881)	NC score	0.056521 (rank : 673)
Query Neighborhood Hits	812	Target Neighborhood Hits	813	Shared Neighborhood Hits	62
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DGKK_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.058639 (rank : 623)
Query Neighborhood Hits	812	Target Neighborhood Hits	378	Shared Neighborhood Hits	105
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIAP1_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.052605 (rank : 752)
Query Neighborhood Hits	812	Target Neighborhood Hits	839	Shared Neighborhood Hits	123
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DOT1L_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.054446 (rank : 719)
Query Neighborhood Hits	812	Target Neighborhood Hits	660	Shared Neighborhood Hits	141
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EFS_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.053097 (rank : 747)
Query Neighborhood Hits	812	Target Neighborhood Hits	389	Shared Neighborhood Hits	111
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EGFR_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.058894 (rank : 615)
Query Neighborhood Hits	812	Target Neighborhood Hits	939	Shared Neighborhood Hits	67
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.058734 (rank : 619)
Query Neighborhood Hits	812	Target Neighborhood Hits	927	Shared Neighborhood Hits	69
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ELN_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.050617 (rank : 786)
Query Neighborhood Hits	812	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ENAH_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.079050 (rank : 434)
Query Neighborhood Hits	812	Target Neighborhood Hits	919	Shared Neighborhood Hits	176
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENL_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.050006 (rank : 792)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	64
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP300_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.071276 (rank : 477)
Query Neighborhood Hits	812	Target Neighborhood Hits	821	Shared Neighborhood Hits	199
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERBB2_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.061317 (rank : 557)
Query Neighborhood Hits	812	Target Neighborhood Hits	1073	Shared Neighborhood Hits	110
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB3_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.055027 (rank : 703)
Query Neighborhood Hits	812	Target Neighborhood Hits	918	Shared Neighborhood Hits	70
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.054361 (rank : 720)
Query Neighborhood Hits	812	Target Neighborhood Hits	898	Shared Neighborhood Hits	70
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.061528 (rank : 555)
Query Neighborhood Hits	812	Target Neighborhood Hits	910	Shared Neighborhood Hits	71
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FA47A_HUMAN
θ value	θ > 10 (rank : 896)	NC score	0.054035 (rank : 726)
Query Neighborhood Hits	812	Target Neighborhood Hits	451	Shared Neighborhood Hits	104
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.053613 (rank : 735)
Query Neighborhood Hits	812	Target Neighborhood Hits	431	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FAK1_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.059905 (rank : 586)
Query Neighborhood Hits	812	Target Neighborhood Hits	850	Shared Neighborhood Hits	66
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.059671 (rank : 594)
Query Neighborhood Hits	812	Target Neighborhood Hits	850	Shared Neighborhood Hits	65
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 900)	NC score	0.060429 (rank : 575)
Query Neighborhood Hits	812	Target Neighborhood Hits	847	Shared Neighborhood Hits	66
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 901)	NC score	0.060066 (rank : 583)
Query Neighborhood Hits	812	Target Neighborhood Hits	851	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FER_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.060850 (rank : 569)
Query Neighborhood Hits	812	Target Neighborhood Hits	1278	Shared Neighborhood Hits	96
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.055748 (rank : 689)
Query Neighborhood Hits	812	Target Neighborhood Hits	978	Shared Neighborhood Hits	76
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.056546 (rank : 671)
Query Neighborhood Hits	812	Target Neighborhood Hits	980	Shared Neighborhood Hits	79
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGR_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.064212 (rank : 523)
Query Neighborhood Hits	812	Target Neighborhood Hits	1067	Shared Neighborhood Hits	115
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.064792 (rank : 512)
Query Neighborhood Hits	812	Target Neighborhood Hits	1069	Shared Neighborhood Hits	116
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FRK_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.062455 (rank : 543)
Query Neighborhood Hits	812	Target Neighborhood Hits	1058	Shared Neighborhood Hits	109
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FYB_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.064319 (rank : 520)
Query Neighborhood Hits	812	Target Neighborhood Hits	379	Shared Neighborhood Hits	110
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

FYN_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.064367 (rank : 518)
Query Neighborhood Hits	812	Target Neighborhood Hits	1078	Shared Neighborhood Hits	117
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.064807 (rank : 511)
Query Neighborhood Hits	812	Target Neighborhood Hits	1073	Shared Neighborhood Hits	115
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GGN_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.072512 (rank : 465)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	91
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 912)	NC score	0.084613 (rank : 407)
Query Neighborhood Hits	812	Target Neighborhood Hits	311	Shared Neighborhood Hits	102
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GSCR1_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.116519 (rank : 322)
Query Neighborhood Hits	812	Target Neighborhood Hits	674	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

GUC2C_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.056559 (rank : 670)
Query Neighborhood Hits	812	Target Neighborhood Hits	624	Shared Neighborhood Hits	58
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2E_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.051692 (rank : 761)
Query Neighborhood Hits	812	Target Neighborhood Hits	692	Shared Neighborhood Hits	58
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.054046 (rank : 725)
Query Neighborhood Hits	812	Target Neighborhood Hits	740	Shared Neighborhood Hits	58
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.060170 (rank : 581)
Query Neighborhood Hits	812	Target Neighborhood Hits	644	Shared Neighborhood Hits	59
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HCK_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.061773 (rank : 552)
Query Neighborhood Hits	812	Target Neighborhood Hits	1035	Shared Neighborhood Hits	112
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.062090 (rank : 546)
Query Neighborhood Hits	812	Target Neighborhood Hits	1029	Shared Neighborhood Hits	111
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HRBL_MOUSE
θ value	θ > 10 (rank : 920)	NC score	0.055020 (rank : 704)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	84
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRX_HUMAN
θ value	θ > 10 (rank : 921)	NC score	0.059441 (rank : 604)
Query Neighborhood Hits	812	Target Neighborhood Hits	825	Shared Neighborhood Hits	142
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IGF1R_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.056344 (rank : 680)
Query Neighborhood Hits	812	Target Neighborhood Hits	977	Shared Neighborhood Hits	70
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.056616 (rank : 668)
Query Neighborhood Hits	812	Target Neighborhood Hits	973	Shared Neighborhood Hits	72
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IKBL_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.307363 (rank : 278)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 925)	NC score	0.301177 (rank : 279)
Query Neighborhood Hits	812	Target Neighborhood Hits	196	Shared Neighborhood Hits	142
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

INSRR_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.058157 (rank : 637)
Query Neighborhood Hits	812	Target Neighborhood Hits	950	Shared Neighborhood Hits	79
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.058350 (rank : 632)
Query Neighborhood Hits	812	Target Neighborhood Hits	961	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.058744 (rank : 618)
Query Neighborhood Hits	812	Target Neighborhood Hits	963	Shared Neighborhood Hits	70
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 929)	NC score	0.057909 (rank : 644)
Query Neighborhood Hits	812	Target Neighborhood Hits	968	Shared Neighborhood Hits	68
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IRAK1_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.059201 (rank : 608)
Query Neighborhood Hits	812	Target Neighborhood Hits	820	Shared Neighborhood Hits	83
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.054180 (rank : 723)
Query Neighborhood Hits	812	Target Neighborhood Hits	784	Shared Neighborhood Hits	70
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK2_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.058301 (rank : 633)
Query Neighborhood Hits	812	Target Neighborhood Hits	714	Shared Neighborhood Hits	64
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

IRAK3_HUMAN
θ value	θ > 10 (rank : 933)	NC score	0.061311 (rank : 558)
Query Neighborhood Hits	812	Target Neighborhood Hits	644	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.060939 (rank : 564)
Query Neighborhood Hits	812	Target Neighborhood Hits	628	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

ITK_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.061034 (rank : 562)
Query Neighborhood Hits	812	Target Neighborhood Hits	1016	Shared Neighborhood Hits	103
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.060254 (rank : 579)
Query Neighborhood Hits	812	Target Neighborhood Hits	985	Shared Neighborhood Hits	94
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAK1_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.050779 (rank : 783)
Query Neighborhood Hits	812	Target Neighborhood Hits	858	Shared Neighborhood Hits	62
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.050649 (rank : 785)
Query Neighborhood Hits	812	Target Neighborhood Hits	854	Shared Neighborhood Hits	62
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

K1543_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.061779 (rank : 551)
Query Neighborhood Hits	812	Target Neighborhood Hits	435	Shared Neighborhood Hits	112
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.054483 (rank : 716)
Query Neighborhood Hits	812	Target Neighborhood Hits	240	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KI67_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.053765 (rank : 732)
Query Neighborhood Hits	812	Target Neighborhood Hits	581	Shared Neighborhood Hits	93
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIT_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.051214 (rank : 772)
Query Neighborhood Hits	812	Target Neighborhood Hits	953	Shared Neighborhood Hits	66
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 943)	NC score	0.050522 (rank : 788)
Query Neighborhood Hits	812	Target Neighborhood Hits	949	Shared Neighborhood Hits	64
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSYK_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.057609 (rank : 651)
Query Neighborhood Hits	812	Target Neighborhood Hits	901	Shared Neighborhood Hits	73
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 945)	NC score	0.058261 (rank : 634)
Query Neighborhood Hits	812	Target Neighborhood Hits	944	Shared Neighborhood Hits	87
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAD1_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.054457 (rank : 717)
Query Neighborhood Hits	812	Target Neighborhood Hits	441	Shared Neighborhood Hits	77
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LCK_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.060536 (rank : 573)
Query Neighborhood Hits	812	Target Neighborhood Hits	987	Shared Neighborhood Hits	96
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 948)	NC score	0.060936 (rank : 565)
Query Neighborhood Hits	812	Target Neighborhood Hits	981	Shared Neighborhood Hits	95
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LCP2_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.070703 (rank : 480)
Query Neighborhood Hits	812	Target Neighborhood Hits	531	Shared Neighborhood Hits	123
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LTK_HUMAN
θ value	θ > 10 (rank : 950)	NC score	0.058843 (rank : 616)
Query Neighborhood Hits	812	Target Neighborhood Hits	774	Shared Neighborhood Hits	63
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 951)	NC score	0.058081 (rank : 638)
Query Neighborhood Hits	812	Target Neighborhood Hits	770	Shared Neighborhood Hits	64
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LYN_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.059720 (rank : 591)
Query Neighborhood Hits	812	Target Neighborhood Hits	1022	Shared Neighborhood Hits	105
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 953)	NC score	0.059898 (rank : 587)
Query Neighborhood Hits	812	Target Neighborhood Hits	1023	Shared Neighborhood Hits	108
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K10_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.064876 (rank : 510)
Query Neighborhood Hits	812	Target Neighborhood Hits	1071	Shared Neighborhood Hits	124
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K11_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.071184 (rank : 478)
Query Neighborhood Hits	812	Target Neighborhood Hits	1136	Shared Neighborhood Hits	170
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

M3K12_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.055188 (rank : 698)
Query Neighborhood Hits	812	Target Neighborhood Hits	940	Shared Neighborhood Hits	100
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.054946 (rank : 706)
Query Neighborhood Hits	812	Target Neighborhood Hits	957	Shared Neighborhood Hits	98
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.051468 (rank : 767)
Query Neighborhood Hits	812	Target Neighborhood Hits	911	Shared Neighborhood Hits	73
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.056644 (rank : 667)
Query Neighborhood Hits	812	Target Neighborhood Hits	892	Shared Neighborhood Hits	62
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 960)	NC score	0.056714 (rank : 664)
Query Neighborhood Hits	812	Target Neighborhood Hits	892	Shared Neighborhood Hits	63
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K9_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.063374 (rank : 533)
Query Neighborhood Hits	812	Target Neighborhood Hits	1123	Shared Neighborhood Hits	145
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.063627 (rank : 528)
Query Neighborhood Hits	812	Target Neighborhood Hits	1087	Shared Neighborhood Hits	129
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MADCA_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.053679 (rank : 733)
Query Neighborhood Hits	812	Target Neighborhood Hits	221	Shared Neighborhood Hits	72
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP1A_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.051403 (rank : 770)
Query Neighborhood Hits	812	Target Neighborhood Hits	1626	Shared Neighborhood Hits	204
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP4_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.056432 (rank : 675)
Query Neighborhood Hits	812	Target Neighborhood Hits	428	Shared Neighborhood Hits	93
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.060619 (rank : 572)
Query Neighborhood Hits	812	Target Neighborhood Hits	409	Shared Neighborhood Hits	93
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.082595 (rank : 417)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MATK_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.058367 (rank : 630)
Query Neighborhood Hits	812	Target Neighborhood Hits	954	Shared Neighborhood Hits	85
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.058168 (rank : 636)
Query Neighborhood Hits	812	Target Neighborhood Hits	952	Shared Neighborhood Hits	86
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MEGF9_MOUSE
θ value	θ > 10 (rank : 970)	NC score	0.056523 (rank : 672)
Query Neighborhood Hits	812	Target Neighborhood Hits	896	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MERTK_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.056979 (rank : 661)
Query Neighborhood Hits	812	Target Neighborhood Hits	988	Shared Neighborhood Hits	70
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 972)	NC score	0.057118 (rank : 657)
Query Neighborhood Hits	812	Target Neighborhood Hits	974	Shared Neighborhood Hits	69
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.058066 (rank : 639)
Query Neighborhood Hits	812	Target Neighborhood Hits	831	Shared Neighborhood Hits	62
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 974)	NC score	0.057959 (rank : 642)
Query Neighborhood Hits	812	Target Neighborhood Hits	844	Shared Neighborhood Hits	64
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MINT_MOUSE
θ value	θ > 10 (rank : 975)	NC score	0.066910 (rank : 496)
Query Neighborhood Hits	812	Target Neighborhood Hits	1514	Shared Neighborhood Hits	243
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLKL_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.067235 (rank : 494)
Query Neighborhood Hits	812	Target Neighborhood Hits	600	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 977)	NC score	0.060238 (rank : 580)
Query Neighborhood Hits	812	Target Neighborhood Hits	707	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLL2_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.088390 (rank : 396)
Query Neighborhood Hits	812	Target Neighborhood Hits	1788	Shared Neighborhood Hits	284
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	θ > 10 (rank : 979)	NC score	0.074678 (rank : 457)
Query Neighborhood Hits	812	Target Neighborhood Hits	722	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLTK_HUMAN
θ value	θ > 10 (rank : 980)	NC score	0.055330 (rank : 695)
Query Neighborhood Hits	812	Target Neighborhood Hits	911	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 981)	NC score	0.055037 (rank : 701)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MOS_HUMAN
θ value	θ > 10 (rank : 982)	NC score	0.052301 (rank : 755)
Query Neighborhood Hits	812	Target Neighborhood Hits	829	Shared Neighborhood Hits	62
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MUC1_MOUSE
θ value	θ > 10 (rank : 983)	NC score	0.074990 (rank : 455)
Query Neighborhood Hits	812	Target Neighborhood Hits	388	Shared Neighborhood Hits	73
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.073583 (rank : 461)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	153
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.106574 (rank : 342)
Query Neighborhood Hits	812	Target Neighborhood Hits	538	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUSK_HUMAN
θ value	θ > 10 (rank : 986)	NC score	0.052100 (rank : 757)
Query Neighborhood Hits	812	Target Neighborhood Hits	1074	Shared Neighborhood Hits	65
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 987)	NC score	0.051501 (rank : 765)
Query Neighborhood Hits	812	Target Neighborhood Hits	1057	Shared Neighborhood Hits	64
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

NCOR2_HUMAN
θ value	θ > 10 (rank : 988)	NC score	0.060759 (rank : 571)
Query Neighborhood Hits	812	Target Neighborhood Hits	870	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	θ > 10 (rank : 989)	NC score	0.050939 (rank : 779)
Query Neighborhood Hits	812	Target Neighborhood Hits	790	Shared Neighborhood Hits	135
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NOLC1_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.081093 (rank : 426)
Query Neighborhood Hits	812	Target Neighborhood Hits	452	Shared Neighborhood Hits	95
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NTRK1_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.056308 (rank : 681)
Query Neighborhood Hits	812	Target Neighborhood Hits	1023	Shared Neighborhood Hits	64
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.053165 (rank : 745)
Query Neighborhood Hits	812	Target Neighborhood Hits	1081	Shared Neighborhood Hits	65
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 993)	NC score	0.053071 (rank : 748)
Query Neighborhood Hits	812	Target Neighborhood Hits	1088	Shared Neighborhood Hits	66
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 994)	NC score	0.053493 (rank : 737)
Query Neighborhood Hits	812	Target Neighborhood Hits	1115	Shared Neighborhood Hits	68
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

PCQAP_MOUSE
θ value	θ > 10 (rank : 995)	NC score	0.051040 (rank : 776)
Query Neighborhood Hits	812	Target Neighborhood Hits	506	Shared Neighborhood Hits	109
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PELP1_HUMAN
θ value	θ > 10 (rank : 996)	NC score	0.055616 (rank : 692)
Query Neighborhood Hits	812	Target Neighborhood Hits	596	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 997)	NC score	0.068401 (rank : 488)
Query Neighborhood Hits	812	Target Neighborhood Hits	709	Shared Neighborhood Hits	166
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PHC2_HUMAN
θ value	θ > 10 (rank : 998)	NC score	0.050936 (rank : 780)
Query Neighborhood Hits	812	Target Neighborhood Hits	388	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PI5PA_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.084081 (rank : 414)
Query Neighborhood Hits	812	Target Neighborhood Hits	749	Shared Neighborhood Hits	210
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA6_MOUSE
θ value	θ > 10 (rank : 1000)	NC score	0.054178 (rank : 724)
Query Neighborhood Hits	812	Target Neighborhood Hits	591	Shared Neighborhood Hits	126
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PO121_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.059493 (rank : 602)
Query Neighborhood Hits	812	Target Neighborhood Hits	344	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.062301 (rank : 545)
Query Neighborhood Hits	812	Target Neighborhood Hits	345	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRG4_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.104672 (rank : 356)
Query Neighborhood Hits	812	Target Neighborhood Hits	764	Shared Neighborhood Hits	162
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRPC_HUMAN
θ value	θ > 10 (rank : 1004)	NC score	0.067571 (rank : 493)
Query Neighborhood Hits	812	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.077391 (rank : 445)
Query Neighborhood Hits	812	Target Neighborhood Hits	44	Shared Neighborhood Hits	26
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR13_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.065454 (rank : 508)
Query Neighborhood Hits	812	Target Neighborhood Hits	105	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 1007)	NC score	0.056105 (rank : 683)
Query Neighborhood Hits	812	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR8_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.060371 (rank : 576)
Query Neighborhood Hits	812	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PTK6_HUMAN
θ value	θ > 10 (rank : 1009)	NC score	0.059674 (rank : 593)
Query Neighborhood Hits	812	Target Neighborhood Hits	1020	Shared Neighborhood Hits	103
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 1010)	NC score	0.059697 (rank : 592)
Query Neighborhood Hits	812	Target Neighborhood Hits	1026	Shared Neighborhood Hits	103
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RAF1_HUMAN
θ value	θ > 10 (rank : 1011)	NC score	0.054893 (rank : 708)
Query Neighborhood Hits	812	Target Neighborhood Hits	886	Shared Neighborhood Hits	70
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 1012)	NC score	0.054691 (rank : 710)
Query Neighborhood Hits	812	Target Neighborhood Hits	886	Shared Neighborhood Hits	72
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RET_HUMAN
θ value	θ > 10 (rank : 1013)	NC score	0.055246 (rank : 697)
Query Neighborhood Hits	812	Target Neighborhood Hits	873	Shared Neighborhood Hits	63
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 1014)	NC score	0.055383 (rank : 694)
Query Neighborhood Hits	812	Target Neighborhood Hits	884	Shared Neighborhood Hits	63
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIPK1_HUMAN
θ value	θ > 10 (rank : 1015)	NC score	0.052216 (rank : 756)
Query Neighborhood Hits	812	Target Neighborhood Hits	891	Shared Neighborhood Hits	71
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 1016)	NC score	0.050418 (rank : 789)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	68
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.069876 (rank : 483)
Query Neighborhood Hits	812	Target Neighborhood Hits	774	Shared Neighborhood Hits	62
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 1018)	NC score	0.064126 (rank : 524)
Query Neighborhood Hits	812	Target Neighborhood Hits	776	Shared Neighborhood Hits	60
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.058690 (rank : 621)
Query Neighborhood Hits	812	Target Neighborhood Hits	828	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RIPK3_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.057983 (rank : 641)
Query Neighborhood Hits	812	Target Neighborhood Hits	867	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RON_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.056004 (rank : 684)
Query Neighborhood Hits	812	Target Neighborhood Hits	842	Shared Neighborhood Hits	65
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 1022)	NC score	0.056358 (rank : 677)
Query Neighborhood Hits	812	Target Neighborhood Hits	836	Shared Neighborhood Hits	62
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.058662 (rank : 622)
Query Neighborhood Hits	812	Target Neighborhood Hits	1018	Shared Neighborhood Hits	68
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.058520 (rank : 627)
Query Neighborhood Hits	812	Target Neighborhood Hits	1025	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 1025)	NC score	0.058508 (rank : 628)
Query Neighborhood Hits	812	Target Neighborhood Hits	1014	Shared Neighborhood Hits	68
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 1026)	NC score	0.059631 (rank : 598)
Query Neighborhood Hits	812	Target Neighborhood Hits	1000	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.057158 (rank : 656)
Query Neighborhood Hits	812	Target Neighborhood Hits	907	Shared Neighborhood Hits	64
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RPB1_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.055946 (rank : 686)
Query Neighborhood Hits	812	Target Neighborhood Hits	362	Shared Neighborhood Hits	95
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.055914 (rank : 687)
Query Neighborhood Hits	812	Target Neighborhood Hits	363	Shared Neighborhood Hits	95
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTP3_MOUSE
θ value	θ > 10 (rank : 1030)	NC score	0.070210 (rank : 482)
Query Neighborhood Hits	812	Target Neighborhood Hits	374	Shared Neighborhood Hits	96
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RYK_HUMAN
θ value	θ > 10 (rank : 1031)	NC score	0.058365 (rank : 631)
Query Neighborhood Hits	812	Target Neighborhood Hits	701	Shared Neighborhood Hits	58
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1032)	NC score	0.057736 (rank : 648)
Query Neighborhood Hits	812	Target Neighborhood Hits	715	Shared Neighborhood Hits	58
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SC24C_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.066395 (rank : 500)
Query Neighborhood Hits	812	Target Neighborhood Hits	662	Shared Neighborhood Hits	181
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELPL_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.051460 (rank : 768)
Query Neighborhood Hits	812	Target Neighborhood Hits	588	Shared Neighborhood Hits	124
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.053482 (rank : 738)
Query Neighborhood Hits	812	Target Neighborhood Hits	118	Shared Neighborhood Hits	43
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.084344 (rank : 412)
Query Neighborhood Hits	812	Target Neighborhood Hits	690	Shared Neighborhood Hits	144
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF3A2_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.068211 (rank : 490)
Query Neighborhood Hits	812	Target Neighborhood Hits	263	Shared Neighborhood Hits	82
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.074279 (rank : 458)
Query Neighborhood Hits	812	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFR15_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.058567 (rank : 624)
Query Neighborhood Hits	812	Target Neighborhood Hits	368	Shared Neighborhood Hits	92
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.051491 (rank : 766)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 1041)	NC score	0.056456 (rank : 674)
Query Neighborhood Hits	812	Target Neighborhood Hits	180	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SLY_HUMAN
θ value	θ > 10 (rank : 1042)	NC score	0.072078 (rank : 472)
Query Neighborhood Hits	812	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SMAP1_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.060532 (rank : 574)
Query Neighborhood Hits	812	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.063777 (rank : 526)
Query Neighborhood Hits	812	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.058473 (rank : 629)
Query Neighborhood Hits	812	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 1046)	NC score	0.057216 (rank : 655)
Query Neighborhood Hits	812	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMR3A_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.062966 (rank : 537)
Query Neighborhood Hits	812	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SPT5H_HUMAN
θ value	θ > 10 (rank : 1048)	NC score	0.050388 (rank : 791)
Query Neighborhood Hits	812	Target Neighborhood Hits	436	Shared Neighborhood Hits	128
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	θ > 10 (rank : 1049)	NC score	0.050799 (rank : 782)
Query Neighborhood Hits	812	Target Neighborhood Hits	437	Shared Neighborhood Hits	129
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRC_HUMAN
θ value	θ > 10 (rank : 1050)	NC score	0.062688 (rank : 542)
Query Neighborhood Hits	812	Target Neighborhood Hits	1058	Shared Neighborhood Hits	116
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 1051)	NC score	0.061524 (rank : 556)
Query Neighborhood Hits	812	Target Neighborhood Hits	1033	Shared Neighborhood Hits	112
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SREC2_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.051829 (rank : 760)
Query Neighborhood Hits	812	Target Neighborhood Hits	645	Shared Neighborhood Hits	103
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SRMS_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.056669 (rank : 666)
Query Neighborhood Hits	812	Target Neighborhood Hits	946	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.056948 (rank : 663)
Query Neighborhood Hits	812	Target Neighborhood Hits	964	Shared Neighborhood Hits	85
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SRRM1_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.109530 (rank : 333)
Query Neighborhood Hits	812	Target Neighborhood Hits	690	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.122829 (rank : 315)
Query Neighborhood Hits	812	Target Neighborhood Hits	966	Shared Neighborhood Hits	204
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SSB4_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.052660 (rank : 751)
Query Neighborhood Hits	812	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

T22D2_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.061304 (rank : 559)
Query Neighborhood Hits	812	Target Neighborhood Hits	250	Shared Neighborhood Hits	84
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TARA_MOUSE
θ value	θ > 10 (rank : 1059)	NC score	0.066385 (rank : 501)
Query Neighborhood Hits	812	Target Neighborhood Hits	1133	Shared Neighborhood Hits	177
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.101389 (rank : 369)
Query Neighborhood Hits	812	Target Neighborhood Hits	768	Shared Neighborhood Hits	186
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TB182_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.061971 (rank : 548)
Query Neighborhood Hits	812	Target Neighborhood Hits	414	Shared Neighborhood Hits	105
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCOF_MOUSE
θ value	θ > 10 (rank : 1062)	NC score	0.080853 (rank : 428)
Query Neighborhood Hits	812	Target Neighborhood Hits	471	Shared Neighborhood Hits	97
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.054344 (rank : 721)
Query Neighborhood Hits	812	Target Neighborhood Hits	929	Shared Neighborhood Hits	122
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1064)	NC score	0.054451 (rank : 718)
Query Neighborhood Hits	812	Target Neighborhood Hits	947	Shared Neighborhood Hits	126
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEC_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.061835 (rank : 550)
Query Neighborhood Hits	812	Target Neighborhood Hits	1006	Shared Neighborhood Hits	103
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1066)	NC score	0.060887 (rank : 567)
Query Neighborhood Hits	812	Target Neighborhood Hits	1006	Shared Neighborhood Hits	104
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TESK2_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.051095 (rank : 774)
Query Neighborhood Hits	812	Target Neighborhood Hits	851	Shared Neighborhood Hits	67
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TIE1_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.063411 (rank : 531)
Query Neighborhood Hits	812	Target Neighborhood Hits	1241	Shared Neighborhood Hits	86
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.063623 (rank : 529)
Query Neighborhood Hits	812	Target Neighborhood Hits	1266	Shared Neighborhood Hits	88
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.062912 (rank : 538)
Query Neighborhood Hits	812	Target Neighborhood Hits	1192	Shared Neighborhood Hits	86
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.062856 (rank : 539)
Query Neighborhood Hits	812	Target Neighborhood Hits	1204	Shared Neighborhood Hits	83
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TM108_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.064442 (rank : 516)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.053141 (rank : 746)
Query Neighborhood Hits	812	Target Neighborhood Hits	140	Shared Neighborhood Hits	57
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TNK1_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.061673 (rank : 554)
Query Neighborhood Hits	812	Target Neighborhood Hits	806	Shared Neighborhood Hits	69
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TRDN_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.053495 (rank : 736)
Query Neighborhood Hits	812	Target Neighborhood Hits	542	Shared Neighborhood Hits	50
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC4_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.072270 (rank : 469)
Query Neighborhood Hits	812	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	θ > 10 (rank : 1077)	NC score	0.072313 (rank : 468)
Query Neighborhood Hits	812	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.075938 (rank : 449)
Query Neighborhood Hits	812	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.077417 (rank : 444)
Query Neighborhood Hits	812	Target Neighborhood Hits	124	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPV1_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.209758 (rank : 290)
Query Neighborhood Hits	812	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV3_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.218634 (rank : 289)
Query Neighborhood Hits	812	Target Neighborhood Hits	188	Shared Neighborhood Hits	133
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.115581 (rank : 323)
Query Neighborhood Hits	812	Target Neighborhood Hits	150	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 1083)	NC score	0.106330 (rank : 343)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	79
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TXK_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.063259 (rank : 534)
Query Neighborhood Hits	812	Target Neighborhood Hits	971	Shared Neighborhood Hits	97
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1085)	NC score	0.063620 (rank : 530)
Query Neighborhood Hits	812	Target Neighborhood Hits	980	Shared Neighborhood Hits	99
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TXND2_HUMAN
θ value	θ > 10 (rank : 1086)	NC score	0.075298 (rank : 452)
Query Neighborhood Hits	812	Target Neighborhood Hits	793	Shared Neighborhood Hits	126
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TYRO3_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.056425 (rank : 676)
Query Neighborhood Hits	812	Target Neighborhood Hits	995	Shared Neighborhood Hits	67
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.056569 (rank : 669)
Query Neighborhood Hits	812	Target Neighborhood Hits	1007	Shared Neighborhood Hits	66
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UFO_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.057018 (rank : 659)
Query Neighborhood Hits	812	Target Neighborhood Hits	981	Shared Neighborhood Hits	77
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.057044 (rank : 658)
Query Neighborhood Hits	812	Target Neighborhood Hits	988	Shared Neighborhood Hits	70
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

VASP_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.053990 (rank : 727)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	74
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VCX3_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.050391 (rank : 790)
Query Neighborhood Hits	812	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

WASF1_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.050595 (rank : 787)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	88
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.051033 (rank : 777)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASL_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.064212 (rank : 522)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	104
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.067008 (rank : 495)
Query Neighborhood Hits	812	Target Neighborhood Hits	339	Shared Neighborhood Hits	109
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.051610 (rank : 763)
Query Neighborhood Hits	812	Target Neighborhood Hits	195	Shared Neighborhood Hits	81
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 1098)	NC score	0.088192 (rank : 397)
Query Neighborhood Hits	812	Target Neighborhood Hits	354	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 1099)	NC score	0.089820 (rank : 392)
Query Neighborhood Hits	812	Target Neighborhood Hits	362	Shared Neighborhood Hits	108
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WNK2_HUMAN
θ value	θ > 10 (rank : 1100)	NC score	0.061760 (rank : 553)
Query Neighborhood Hits	812	Target Neighborhood Hits	1407	Shared Neighborhood Hits	230
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK4_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.051211 (rank : 773)
Query Neighborhood Hits	812	Target Neighborhood Hits	1043	Shared Neighborhood Hits	156
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YES_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.064559 (rank : 514)
Query Neighborhood Hits	812	Target Neighborhood Hits	1059	Shared Neighborhood Hits	115
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1103)	NC score	0.064379 (rank : 517)
Query Neighborhood Hits	812	Target Neighborhood Hits	1052	Shared Neighborhood Hits	112
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YLPM1_HUMAN
θ value	θ > 10 (rank : 1104)	NC score	0.081233 (rank : 424)
Query Neighborhood Hits	812	Target Neighborhood Hits	670	Shared Neighborhood Hits	165
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 1105)	NC score	0.080140 (rank : 429)
Query Neighborhood Hits	812	Target Neighborhood Hits	505	Shared Neighborhood Hits	125
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZAP70_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.060884 (rank : 568)
Query Neighborhood Hits	812	Target Neighborhood Hits	893	Shared Neighborhood Hits	75
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1107)	NC score	0.059877 (rank : 588)
Query Neighborhood Hits	812	Target Neighborhood Hits	905	Shared Neighborhood Hits	74
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZN207_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.069414 (rank : 485)
Query Neighborhood Hits	812	Target Neighborhood Hits	326	Shared Neighborhood Hits	69
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN385_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.065036 (rank : 509)
Query Neighborhood Hits	812	Target Neighborhood Hits	614	Shared Neighborhood Hits	147
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

Hits sorted by NC score

CSKI2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	812	Target Neighborhood Hits	812	Shared Neighborhood Hits	812
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_HUMAN
NC score	0.976540 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	812	Target Neighborhood Hits	747	Shared Neighborhood Hits	539
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI1_HUMAN
NC score	0.942440 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	812	Target Neighborhood Hits	997	Shared Neighborhood Hits	520
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
NC score	0.941009 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	812	Target Neighborhood Hits	1031	Shared Neighborhood Hits	529
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANKS1_HUMAN
NC score	0.894832 (rank : 5)	θ value	1.01294e-51 (rank : 5)
Query Neighborhood Hits	812	Target Neighborhood Hits	438	Shared Neighborhood Hits	348
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
NC score	0.889573 (rank : 6)	θ value	1.04822e-48 (rank : 6)
Query Neighborhood Hits	812	Target Neighborhood Hits	453	Shared Neighborhood Hits	348
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR29_HUMAN
NC score	0.877713 (rank : 7)	θ value	4.15078e-21 (rank : 28)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.873951 (rank : 8)	θ value	1.92812e-18 (rank : 39)
Query Neighborhood Hits	812	Target Neighborhood Hits	301	Shared Neighborhood Hits	287
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.872215 (rank : 9)	θ value	9.56915e-18 (rank : 47)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.870977 (rank : 10)	θ value	1.86321e-21 (rank : 24)
Query Neighborhood Hits	812	Target Neighborhood Hits	439	Shared Neighborhood Hits	304
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR16_HUMAN
NC score	0.868322 (rank : 11)	θ value	2.20605e-14 (rank : 76)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR42_HUMAN
NC score	0.867747 (rank : 12)	θ value	3.17815e-21 (rank : 27)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR50_HUMAN
NC score	0.865806 (rank : 13)	θ value	5.79196e-23 (rank : 20)
Query Neighborhood Hits	812	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
NC score	0.864378 (rank : 14)	θ value	1.29031e-22 (rank : 21)
Query Neighborhood Hits	812	Target Neighborhood Hits	477	Shared Neighborhood Hits	366
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR42_MOUSE
NC score	0.863526 (rank : 15)	θ value	5.99374e-20 (rank : 33)
Query Neighborhood Hits	812	Target Neighborhood Hits	334	Shared Neighborhood Hits	279
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB7_HUMAN
NC score	0.863088 (rank : 16)	θ value	2.5182e-18 (rank : 40)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
NC score	0.863063 (rank : 17)	θ value	3.28887e-18 (rank : 42)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB10_MOUSE
NC score	0.860865 (rank : 18)	θ value	5.99374e-20 (rank : 34)
Query Neighborhood Hits	812	Target Neighborhood Hits	301	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB3_MOUSE
NC score	0.860793 (rank : 19)	θ value	5.60996e-18 (rank : 44)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	294
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB10_HUMAN
NC score	0.859928 (rank : 20)	θ value	7.32683e-18 (rank : 45)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB3_HUMAN
NC score	0.859659 (rank : 21)	θ value	1.92812e-18 (rank : 38)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR44_HUMAN
NC score	0.856509 (rank : 22)	θ value	5.23862e-24 (rank : 14)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.856395 (rank : 23)	θ value	2.12685e-25 (rank : 13)
Query Neighborhood Hits	812	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

TNKS2_HUMAN
NC score	0.856039 (rank : 24)	θ value	4.43474e-23 (rank : 19)
Query Neighborhood Hits	812	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR28_HUMAN
NC score	0.854546 (rank : 25)	θ value	1.99067e-23 (rank : 16)
Query Neighborhood Hits	812	Target Neighborhood Hits	314	Shared Neighborhood Hits	292
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK1_HUMAN
NC score	0.853744 (rank : 26)	θ value	7.80994e-28 (rank : 8)
Query Neighborhood Hits	812	Target Neighborhood Hits	416	Shared Neighborhood Hits	305
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.852819 (rank : 27)	θ value	7.80994e-28 (rank : 9)
Query Neighborhood Hits	812	Target Neighborhood Hits	430	Shared Neighborhood Hits	302
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

INVS_HUMAN
NC score	0.852322 (rank : 28)	θ value	2.5182e-18 (rank : 41)
Query Neighborhood Hits	812	Target Neighborhood Hits	455	Shared Neighborhood Hits	322
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANR52_MOUSE
NC score	0.849629 (rank : 29)	θ value	4.43474e-23 (rank : 18)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.849338 (rank : 30)	θ value	3.39556e-23 (rank : 17)
Query Neighborhood Hits	812	Target Neighborhood Hits	322	Shared Neighborhood Hits	296
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

FANK1_HUMAN
NC score	0.849233 (rank : 31)	θ value	2.43908e-13 (rank : 82)
Query Neighborhood Hits	812	Target Neighborhood Hits	326	Shared Neighborhood Hits	292
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

INVS_MOUSE
NC score	0.848387 (rank : 32)	θ value	4.29542e-18 (rank : 43)
Query Neighborhood Hits	812	Target Neighborhood Hits	609	Shared Neighborhood Hits	360
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB13_MOUSE
NC score	0.848355 (rank : 33)	θ value	8.95645e-16 (rank : 61)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

FANK1_MOUSE
NC score	0.848237 (rank : 34)	θ value	1.02475e-11 (rank : 102)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	291
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ASB13_HUMAN
NC score	0.848182 (rank : 35)	θ value	1.52774e-15 (rank : 65)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANKR2_MOUSE
NC score	0.845242 (rank : 36)	θ value	1.16975e-15 (rank : 64)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANK3_HUMAN
NC score	0.843877 (rank : 37)	θ value	1.33217e-27 (rank : 10)
Query Neighborhood Hits	812	Target Neighborhood Hits	853	Shared Neighborhood Hits	351
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR23_MOUSE
NC score	0.843607 (rank : 38)	θ value	1.29331e-14 (rank : 70)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB2_HUMAN
NC score	0.843550 (rank : 39)	θ value	1.92812e-18 (rank : 37)
Query Neighborhood Hits	812	Target Neighborhood Hits	309	Shared Neighborhood Hits	288
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKR2_HUMAN
NC score	0.843449 (rank : 40)	θ value	5.25075e-16 (rank : 58)
Query Neighborhood Hits	812	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR39_HUMAN
NC score	0.843019 (rank : 41)	θ value	6.64225e-11 (rank : 110)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	277
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
NC score	0.842940 (rank : 42)	θ value	2.28291e-11 (rank : 104)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB2_MOUSE
NC score	0.838681 (rank : 43)	θ value	8.95645e-16 (rank : 62)
Query Neighborhood Hits	812	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR23_HUMAN
NC score	0.837970 (rank : 44)	θ value	1.2105e-12 (rank : 93)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	283
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

MYPT1_MOUSE
NC score	0.835452 (rank : 45)	θ value	2.7842e-17 (rank : 49)
Query Neighborhood Hits	812	Target Neighborhood Hits	539	Shared Neighborhood Hits	309
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANKR1_HUMAN
NC score	0.834047 (rank : 46)	θ value	7.84624e-12 (rank : 100)
Query Neighborhood Hits	812	Target Neighborhood Hits	308	Shared Neighborhood Hits	278
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKS6_HUMAN
NC score	0.833830 (rank : 47)	θ value	1.68911e-14 (rank : 72)
Query Neighborhood Hits	812	Target Neighborhood Hits	411	Shared Neighborhood Hits	330
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
NC score	0.833672 (rank : 48)	θ value	1.09485e-13 (rank : 81)
Query Neighborhood Hits	812	Target Neighborhood Hits	435	Shared Neighborhood Hits	333
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKR1_MOUSE
NC score	0.833519 (rank : 49)	θ value	7.84624e-12 (rank : 101)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	285
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

TRPA1_MOUSE
NC score	0.833436 (rank : 50)	θ value	3.40345e-15 (rank : 67)
Query Neighborhood Hits	812	Target Neighborhood Hits	343	Shared Neighborhood Hits	294
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.833366 (rank : 51)	θ value	6.85773e-16 (rank : 60)
Query Neighborhood Hits	812	Target Neighborhood Hits	339	Shared Neighborhood Hits	293
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

GABP2_MOUSE
NC score	0.832170 (rank : 52)	θ value	1.58096e-12 (rank : 94)
Query Neighborhood Hits	812	Target Neighborhood Hits	429	Shared Neighborhood Hits	297
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR49_MOUSE
NC score	0.830554 (rank : 53)	θ value	9.59137e-10 (rank : 126)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

GABP3_MOUSE
NC score	0.830540 (rank : 54)	θ value	9.26847e-13 (rank : 92)
Query Neighborhood Hits	812	Target Neighborhood Hits	330	Shared Neighborhood Hits	280
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GABP2_HUMAN
NC score	0.829943 (rank : 55)	θ value	5.43371e-13 (rank : 87)
Query Neighborhood Hits	812	Target Neighborhood Hits	454	Shared Neighborhood Hits	296
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

CDN2C_HUMAN
NC score	0.829457 (rank : 56)	θ value	1.47974e-10 (rank : 113)
Query Neighborhood Hits	812	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

PP16A_MOUSE
NC score	0.829339 (rank : 57)	θ value	8.10077e-17 (rank : 55)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	284
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2C_MOUSE
NC score	0.828689 (rank : 58)	θ value	4.30538e-10 (rank : 120)
Query Neighborhood Hits	812	Target Neighborhood Hits	270	Shared Neighborhood Hits	268
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR49_HUMAN
NC score	0.826272 (rank : 59)	θ value	2.13673e-09 (rank : 131)
Query Neighborhood Hits	812	Target Neighborhood Hits	282	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

BCL3_HUMAN
NC score	0.825312 (rank : 60)	θ value	1.74796e-11 (rank : 103)
Query Neighborhood Hits	812	Target Neighborhood Hits	324	Shared Neighborhood Hits	290
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ASB8_MOUSE
NC score	0.824477 (rank : 61)	θ value	8.11959e-09 (rank : 143)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PA2G6_MOUSE
NC score	0.823894 (rank : 62)	θ value	1.68911e-14 (rank : 74)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB8_HUMAN
NC score	0.823859 (rank : 63)	θ value	2.79066e-09 (rank : 134)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PP16A_HUMAN
NC score	0.823028 (rank : 64)	θ value	1.68911e-14 (rank : 75)
Query Neighborhood Hits	812	Target Neighborhood Hits	340	Shared Neighborhood Hits	293
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_HUMAN
NC score	0.822887 (rank : 65)	θ value	8.95645e-16 (rank : 63)
Query Neighborhood Hits	812	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

BCL3_MOUSE
NC score	0.822083 (rank : 66)	θ value	2.28291e-11 (rank : 106)
Query Neighborhood Hits	812	Target Neighborhood Hits	388	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB9_HUMAN
NC score	0.821984 (rank : 67)	θ value	1.29331e-14 (rank : 71)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	256
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MIB1_HUMAN
NC score	0.821836 (rank : 68)	θ value	3.51386e-20 (rank : 30)
Query Neighborhood Hits	812	Target Neighborhood Hits	470	Shared Neighborhood Hits	302
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MYPT2_HUMAN
NC score	0.821714 (rank : 69)	θ value	1.86321e-21 (rank : 25)
Query Neighborhood Hits	812	Target Neighborhood Hits	707	Shared Neighborhood Hits	309
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB16_MOUSE
NC score	0.821580 (rank : 70)	θ value	2.98157e-11 (rank : 107)
Query Neighborhood Hits	812	Target Neighborhood Hits	306	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MIB1_MOUSE
NC score	0.821515 (rank : 71)	θ value	3.51386e-20 (rank : 31)
Query Neighborhood Hits	812	Target Neighborhood Hits	471	Shared Neighborhood Hits	301
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PP16B_MOUSE
NC score	0.820695 (rank : 72)	θ value	9.90251e-15 (rank : 69)
Query Neighborhood Hits	812	Target Neighborhood Hits	302	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ASB5_HUMAN
NC score	0.819475 (rank : 73)	θ value	4.74913e-17 (rank : 51)
Query Neighborhood Hits	812	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
NC score	0.817323 (rank : 74)	θ value	8.10077e-17 (rank : 53)
Query Neighborhood Hits	812	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB15_HUMAN
NC score	0.816067 (rank : 75)	θ value	4.16044e-13 (rank : 84)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MYPT1_HUMAN
NC score	0.815461 (rank : 76)	θ value	1.63225e-17 (rank : 48)
Query Neighborhood Hits	812	Target Neighborhood Hits	723	Shared Neighborhood Hits	314
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ASB11_HUMAN
NC score	0.814971 (rank : 77)	θ value	5.43371e-13 (rank : 86)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKS3_MOUSE
NC score	0.813577 (rank : 78)	θ value	7.34386e-10 (rank : 123)
Query Neighborhood Hits	812	Target Neighborhood Hits	355	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB9_MOUSE
NC score	0.813369 (rank : 79)	θ value	6.85773e-16 (rank : 59)
Query Neighborhood Hits	812	Target Neighborhood Hits	257	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MIB2_MOUSE
NC score	0.812612 (rank : 80)	θ value	8.10077e-17 (rank : 54)
Query Neighborhood Hits	812	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ASB11_MOUSE
NC score	0.812362 (rank : 81)	θ value	7.09661e-13 (rank : 90)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MIB2_HUMAN
NC score	0.812196 (rank : 82)	θ value	9.56915e-18 (rank : 46)
Query Neighborhood Hits	812	Target Neighborhood Hits	438	Shared Neighborhood Hits	294
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB16_HUMAN
NC score	0.811355 (rank : 83)	θ value	1.17247e-07 (rank : 162)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	269
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANKS3_HUMAN
NC score	0.811243 (rank : 84)	θ value	3.29651e-10 (rank : 115)
Query Neighborhood Hits	812	Target Neighborhood Hits	355	Shared Neighborhood Hits	284
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CDN2D_HUMAN
NC score	0.810941 (rank : 85)	θ value	2.61198e-07 (rank : 167)
Query Neighborhood Hits	812	Target Neighborhood Hits	268	Shared Neighborhood Hits	268
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANKR5_MOUSE
NC score	0.808756 (rank : 86)	θ value	6.21693e-09 (rank : 140)
Query Neighborhood Hits	812	Target Neighborhood Hits	298	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANK2_HUMAN
NC score	0.808236 (rank : 87)	θ value	2.51237e-26 (rank : 11)
Query Neighborhood Hits	812	Target Neighborhood Hits	1615	Shared Neighborhood Hits	484
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB15_MOUSE
NC score	0.808020 (rank : 88)	θ value	2.69671e-12 (rank : 96)
Query Neighborhood Hits	812	Target Neighborhood Hits	292	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKR5_HUMAN
NC score	0.805521 (rank : 89)	θ value	1.38499e-08 (rank : 147)
Query Neighborhood Hits	812	Target Neighborhood Hits	297	Shared Neighborhood Hits	281
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB14_MOUSE
NC score	0.805461 (rank : 90)	θ value	8.67504e-11 (rank : 111)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASZ1_HUMAN
NC score	0.803980 (rank : 91)	θ value	2.79066e-09 (rank : 135)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CDN2D_MOUSE
NC score	0.802641 (rank : 92)	θ value	1.99992e-07 (rank : 165)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	264
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

PA2G6_HUMAN
NC score	0.801761 (rank : 93)	θ value	2.88788e-06 (rank : 191)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR10_HUMAN
NC score	0.801571 (rank : 94)	θ value	2.13673e-09 (rank : 129)
Query Neighborhood Hits	812	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

MTPN_MOUSE
NC score	0.801474 (rank : 95)	θ value	4.1701e-05 (rank : 230)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANR10_MOUSE
NC score	0.800983 (rank : 96)	θ value	4.0297e-08 (rank : 152)
Query Neighborhood Hits	812	Target Neighborhood Hits	273	Shared Neighborhood Hits	264
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

IKBA_HUMAN
NC score	0.800565 (rank : 97)	θ value	5.62301e-10 (rank : 122)
Query Neighborhood Hits	812	Target Neighborhood Hits	280	Shared Neighborhood Hits	270
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASB4_HUMAN
NC score	0.799645 (rank : 98)	θ value	2.28291e-11 (rank : 105)
Query Neighborhood Hits	812	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASZ1_MOUSE
NC score	0.798980 (rank : 99)	θ value	5.26297e-08 (rank : 157)
Query Neighborhood Hits	812	Target Neighborhood Hits	319	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CT086_HUMAN
NC score	0.798557 (rank : 100)	θ value	0.000158464 (rank : 247)
Query Neighborhood Hits	812	Target Neighborhood Hits	277	Shared Neighborhood Hits	273
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ASB4_MOUSE
NC score	0.798174 (rank : 101)	θ value	3.89403e-11 (rank : 108)
Query Neighborhood Hits	812	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

MTPN_HUMAN
NC score	0.798087 (rank : 102)	θ value	4.1701e-05 (rank : 229)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANRA2_HUMAN
NC score	0.797221 (rank : 103)	θ value	3.08544e-08 (rank : 151)
Query Neighborhood Hits	812	Target Neighborhood Hits	288	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

EHMT1_HUMAN
NC score	0.795875 (rank : 104)	θ value	3.07829e-16 (rank : 57)
Query Neighborhood Hits	812	Target Neighborhood Hits	417	Shared Neighborhood Hits	308
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANRA2_MOUSE
NC score	0.793724 (rank : 105)	θ value	8.97725e-08 (rank : 160)
Query Neighborhood Hits	812	Target Neighborhood Hits	287	Shared Neighborhood Hits	278
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANKR7_HUMAN
NC score	0.792385 (rank : 106)	θ value	4.76016e-09 (rank : 139)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	274
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR22_HUMAN
NC score	0.792179 (rank : 107)	θ value	1.80886e-08 (rank : 149)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	238
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

IKBA_MOUSE
NC score	0.789467 (rank : 108)	θ value	1.25267e-09 (rank : 127)
Query Neighborhood Hits	812	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IKBE_MOUSE
NC score	0.788567 (rank : 109)	θ value	3.29651e-10 (rank : 118)
Query Neighborhood Hits	812	Target Neighborhood Hits	308	Shared Neighborhood Hits	277
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

RN5A_HUMAN
NC score	0.787489 (rank : 110)	θ value	1.133e-10 (rank : 112)
Query Neighborhood Hits	812	Target Neighborhood Hits	608	Shared Neighborhood Hits	303
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB12_MOUSE
NC score	0.787439 (rank : 111)	θ value	1.38499e-08 (rank : 148)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

BARD1_HUMAN
NC score	0.786921 (rank : 112)	θ value	3.29651e-10 (rank : 116)
Query Neighborhood Hits	812	Target Neighborhood Hits	427	Shared Neighborhood Hits	290
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR46_HUMAN
NC score	0.786635 (rank : 113)	θ value	0.00020696 (rank : 250)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	276
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

RFXK_HUMAN
NC score	0.786247 (rank : 114)	θ value	3.77169e-06 (rank : 199)
Query Neighborhood Hits	812	Target Neighborhood Hits	282	Shared Neighborhood Hits	269
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

BARD1_MOUSE
NC score	0.785759 (rank : 115)	θ value	4.30538e-10 (rank : 119)
Query Neighborhood Hits	812	Target Neighborhood Hits	411	Shared Neighborhood Hits	285
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

EHMT2_HUMAN
NC score	0.781479 (rank : 116)	θ value	4.91457e-14 (rank : 78)
Query Neighborhood Hits	812	Target Neighborhood Hits	498	Shared Neighborhood Hits	311
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR46_MOUSE
NC score	0.781316 (rank : 117)	θ value	0.000602161 (rank : 264)
Query Neighborhood Hits	812	Target Neighborhood Hits	274	Shared Neighborhood Hits	270
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB12_HUMAN
NC score	0.781050 (rank : 118)	θ value	0.000158464 (rank : 246)
Query Neighborhood Hits	812	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB1_MOUSE
NC score	0.777480 (rank : 119)	θ value	1.29631e-06 (rank : 183)
Query Neighborhood Hits	812	Target Neighborhood Hits	292	Shared Neighborhood Hits	275
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_HUMAN
NC score	0.776329 (rank : 120)	θ value	2.44474e-05 (rank : 222)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

EHMT2_MOUSE
NC score	0.775782 (rank : 121)	θ value	4.16044e-13 (rank : 85)
Query Neighborhood Hits	812	Target Neighborhood Hits	750	Shared Neighborhood Hits	392
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

AN36B_HUMAN
NC score	0.775659 (rank : 122)	θ value	2.79066e-09 (rank : 133)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	281
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR35_HUMAN
NC score	0.775597 (rank : 123)	θ value	3.07829e-16 (rank : 56)
Query Neighborhood Hits	812	Target Neighborhood Hits	784	Shared Neighborhood Hits	307
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ACBD6_MOUSE
NC score	0.774177 (rank : 124)	θ value	4.45536e-07 (rank : 173)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	287
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR32_HUMAN
NC score	0.772463 (rank : 125)	θ value	2.13673e-09 (rank : 130)
Query Neighborhood Hits	812	Target Neighborhood Hits	270	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBE_HUMAN
NC score	0.770802 (rank : 126)	θ value	3.29651e-10 (rank : 117)
Query Neighborhood Hits	812	Target Neighborhood Hits	288	Shared Neighborhood Hits	270
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ACBD6_HUMAN
NC score	0.767668 (rank : 127)	θ value	5.81887e-07 (rank : 176)
Query Neighborhood Hits	812	Target Neighborhood Hits	304	Shared Neighborhood Hits	284
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

RFXK_MOUSE
NC score	0.766690 (rank : 128)	θ value	0.0113563 (rank : 311)
Query Neighborhood Hits	812	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

IKBB_MOUSE
NC score	0.762819 (rank : 129)	θ value	3.41135e-07 (rank : 172)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

USH1G_HUMAN
NC score	0.761152 (rank : 130)	θ value	1.06045e-08 (rank : 145)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
NC score	0.760984 (rank : 131)	θ value	1.06045e-08 (rank : 146)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR32_MOUSE
NC score	0.759684 (rank : 132)	θ value	6.87365e-08 (rank : 159)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBB_HUMAN
NC score	0.757329 (rank : 133)	θ value	0.000158464 (rank : 248)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ZDH17_HUMAN
NC score	0.754304 (rank : 134)	θ value	3.63628e-17 (rank : 50)
Query Neighborhood Hits	812	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR11_HUMAN
NC score	0.753025 (rank : 135)	θ value	3.76295e-14 (rank : 77)
Query Neighborhood Hits	812	Target Neighborhood Hits	1289	Shared Neighborhood Hits	404
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANS4B_HUMAN
NC score	0.751464 (rank : 136)	θ value	4.45536e-07 (rank : 175)
Query Neighborhood Hits	812	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH17_MOUSE
NC score	0.749962 (rank : 137)	θ value	6.20254e-17 (rank : 52)
Query Neighborhood Hits	812	Target Neighborhood Hits	328	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

POTE8_HUMAN
NC score	0.748939 (rank : 138)	θ value	1.06045e-08 (rank : 144)
Query Neighborhood Hits	812	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANFY1_MOUSE
NC score	0.748036 (rank : 139)	θ value	3.18553e-13 (rank : 83)
Query Neighborhood Hits	812	Target Neighborhood Hits	480	Shared Neighborhood Hits	291
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

CTTB2_HUMAN
NC score	0.747256 (rank : 140)	θ value	1.74391e-19 (rank : 35)
Query Neighborhood Hits	812	Target Neighborhood Hits	1061	Shared Neighborhood Hits	348
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANFY1_HUMAN
NC score	0.746628 (rank : 141)	θ value	7.09661e-13 (rank : 89)
Query Neighborhood Hits	812	Target Neighborhood Hits	480	Shared Neighborhood Hits	285
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

RN5A_MOUSE
NC score	0.744898 (rank : 142)	θ value	5.43371e-13 (rank : 88)
Query Neighborhood Hits	812	Target Neighborhood Hits	899	Shared Neighborhood Hits	326
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR19_HUMAN
NC score	0.744299 (rank : 143)	θ value	5.62301e-10 (rank : 121)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	268
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR41_HUMAN
NC score	0.740682 (rank : 144)	θ value	0.000461057 (rank : 259)
Query Neighborhood Hits	812	Target Neighborhood Hits	332	Shared Neighborhood Hits	272
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ZDH13_MOUSE
NC score	0.740435 (rank : 145)	θ value	4.91457e-14 (rank : 79)
Query Neighborhood Hits	812	Target Neighborhood Hits	329	Shared Neighborhood Hits	279
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

SHAN1_HUMAN
NC score	0.740120 (rank : 146)	θ value	6.00763e-12 (rank : 99)
Query Neighborhood Hits	812	Target Neighborhood Hits	1041	Shared Neighborhood Hits	471
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANS4B_MOUSE
NC score	0.738955 (rank : 147)	θ value	2.88788e-06 (rank : 189)
Query Neighborhood Hits	812	Target Neighborhood Hits	294	Shared Neighborhood Hits	258
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH13_HUMAN
NC score	0.738332 (rank : 148)	θ value	7.09661e-13 (rank : 91)
Query Neighborhood Hits	812	Target Neighborhood Hits	322	Shared Neighborhood Hits	275
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

AN36A_HUMAN
NC score	0.732941 (rank : 149)	θ value	0.000602161 (rank : 263)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR37_HUMAN
NC score	0.729393 (rank : 150)	θ value	5.44631e-05 (rank : 233)
Query Neighborhood Hits	812	Target Neighborhood Hits	247	Shared Neighborhood Hits	243
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANKY2_HUMAN
NC score	0.726100 (rank : 151)	θ value	4.92598e-06 (rank : 201)
Query Neighborhood Hits	812	Target Neighborhood Hits	306	Shared Neighborhood Hits	261
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR37_MOUSE
NC score	0.716081 (rank : 152)	θ value	1.87187e-05 (rank : 217)
Query Neighborhood Hits	812	Target Neighborhood Hits	237	Shared Neighborhood Hits	233
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

SNCAP_HUMAN
NC score	0.715942 (rank : 153)	θ value	3.77169e-06 (rank : 200)
Query Neighborhood Hits	812	Target Neighborhood Hits	313	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR15_HUMAN
NC score	0.714340 (rank : 154)	θ value	3.08544e-08 (rank : 150)
Query Neighborhood Hits	812	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR12_HUMAN
NC score	0.712604 (rank : 155)	θ value	1.68911e-14 (rank : 73)
Query Neighborhood Hits	812	Target Neighborhood Hits	1081	Shared Neighborhood Hits	315
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR47_MOUSE
NC score	0.710610 (rank : 156)	θ value	4.45536e-07 (rank : 174)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

BCOR_MOUSE
NC score	0.705298 (rank : 157)	θ value	3.41135e-07 (rank : 171)
Query Neighborhood Hits	812	Target Neighborhood Hits	521	Shared Neighborhood Hits	311
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANKY2_MOUSE
NC score	0.703771 (rank : 158)	θ value	8.40245e-06 (rank : 205)
Query Neighborhood Hits	812	Target Neighborhood Hits	316	Shared Neighborhood Hits	262
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR21_HUMAN
NC score	0.703721 (rank : 159)	θ value	8.11959e-09 (rank : 142)
Query Neighborhood Hits	812	Target Neighborhood Hits	864	Shared Neighborhood Hits	310
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.703183 (rank : 160)	θ value	3.64472e-09 (rank : 137)
Query Neighborhood Hits	812	Target Neighborhood Hits	893	Shared Neighborhood Hits	314
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

KRIT1_MOUSE
NC score	0.700385 (rank : 161)	θ value	7.34386e-10 (rank : 124)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	228
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NFKB1_HUMAN
NC score	0.700251 (rank : 162)	θ value	1.99992e-07 (rank : 166)
Query Neighborhood Hits	812	Target Neighborhood Hits	306	Shared Neighborhood Hits	274
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.699707 (rank : 163)	θ value	2.61198e-07 (rank : 168)
Query Neighborhood Hits	812	Target Neighborhood Hits	300	Shared Neighborhood Hits	271
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

BCOR_HUMAN
NC score	0.698042 (rank : 164)	θ value	3.41135e-07 (rank : 170)
Query Neighborhood Hits	812	Target Neighborhood Hits	609	Shared Neighborhood Hits	339
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

NFKB2_HUMAN
NC score	0.693752 (rank : 165)	θ value	2.61198e-07 (rank : 169)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	283
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

KRIT1_HUMAN
NC score	0.690925 (rank : 166)	θ value	4.0297e-08 (rank : 153)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	221
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR47_HUMAN
NC score	0.687680 (rank : 167)	θ value	3.77169e-06 (rank : 197)
Query Neighborhood Hits	812	Target Neighborhood Hits	369	Shared Neighborhood Hits	272
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB6_HUMAN
NC score	0.687187 (rank : 168)	θ value	0.0431538 (rank : 339)
Query Neighborhood Hits	812	Target Neighborhood Hits	256	Shared Neighborhood Hits	243
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

POT14_HUMAN
NC score	0.686277 (rank : 169)	θ value	1.09739e-05 (rank : 210)
Query Neighborhood Hits	812	Target Neighborhood Hits	403	Shared Neighborhood Hits	276
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

CD2A1_MOUSE
NC score	0.683971 (rank : 170)	θ value	0.000461057 (rank : 260)
Query Neighborhood Hits	812	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ASB6_MOUSE
NC score	0.680418 (rank : 171)	θ value	0.163984 (rank : 379)
Query Neighborhood Hits	812	Target Neighborhood Hits	264	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

NFKB2_MOUSE
NC score	0.678407 (rank : 172)	θ value	9.92553e-07 (rank : 181)
Query Neighborhood Hits	812	Target Neighborhood Hits	326	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR33_MOUSE
NC score	0.671176 (rank : 173)	θ value	3.19293e-05 (rank : 226)
Query Neighborhood Hits	812	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR25_HUMAN
NC score	0.666363 (rank : 174)	θ value	6.43352e-06 (rank : 203)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	281
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

OSTF1_MOUSE
NC score	0.664353 (rank : 175)	θ value	9.92553e-07 (rank : 182)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	302
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OSBL1_HUMAN
NC score	0.661343 (rank : 176)	θ value	3.89403e-11 (rank : 109)
Query Neighborhood Hits	812	Target Neighborhood Hits	368	Shared Neighborhood Hits	283
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR25_MOUSE
NC score	0.657107 (rank : 177)	θ value	2.44474e-05 (rank : 220)
Query Neighborhood Hits	812	Target Neighborhood Hits	398	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

MPP8_HUMAN
NC score	0.653693 (rank : 178)	θ value	7.34386e-10 (rank : 125)
Query Neighborhood Hits	812	Target Neighborhood Hits	948	Shared Neighborhood Hits	282
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OSBL1_MOUSE
NC score	0.649289 (rank : 179)	θ value	6.21693e-09 (rank : 141)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	283
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSTF1_HUMAN
NC score	0.648647 (rank : 180)	θ value	7.59969e-07 (rank : 179)
Query Neighborhood Hits	812	Target Neighborhood Hits	466	Shared Neighborhood Hits	300
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR38_HUMAN
NC score	0.647674 (rank : 181)	θ value	2.44474e-05 (rank : 221)
Query Neighborhood Hits	812	Target Neighborhood Hits	443	Shared Neighborhood Hits	257
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

POT22_HUMAN
NC score	0.647017 (rank : 182)	θ value	1.09739e-05 (rank : 211)
Query Neighborhood Hits	812	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR33_HUMAN
NC score	0.646827 (rank : 183)	θ value	0.0148317 (rank : 314)
Query Neighborhood Hits	812	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CDN2B_MOUSE
NC score	0.646197 (rank : 184)	θ value	3.19293e-05 (rank : 227)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CLPB_MOUSE
NC score	0.642895 (rank : 185)	θ value	0.0193708 (rank : 317)
Query Neighborhood Hits	812	Target Neighborhood Hits	289	Shared Neighborhood Hits	251
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

RAI14_HUMAN
NC score	0.636733 (rank : 186)	θ value	3.51386e-20 (rank : 32)
Query Neighborhood Hits	812	Target Neighborhood Hits	1367	Shared Neighborhood Hits	353
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

A20A3_HUMAN
NC score	0.632699 (rank : 187)	θ value	3.77169e-06 (rank : 194)
Query Neighborhood Hits	812	Target Neighborhood Hits	692	Shared Neighborhood Hits	290
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.632041 (rank : 188)	θ value	3.77169e-06 (rank : 193)
Query Neighborhood Hits	812	Target Neighborhood Hits	716	Shared Neighborhood Hits	289
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.631062 (rank : 189)	θ value	2.88788e-06 (rank : 188)
Query Neighborhood Hits	812	Target Neighborhood Hits	698	Shared Neighborhood Hits	284
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR45_MOUSE
NC score	0.629830 (rank : 190)	θ value	0.000121331 (rank : 243)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

A20A4_HUMAN
NC score	0.628099 (rank : 191)	θ value	3.77169e-06 (rank : 195)
Query Neighborhood Hits	812	Target Neighborhood Hits	710	Shared Neighborhood Hits	289
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR38_MOUSE
NC score	0.622068 (rank : 192)	θ value	0.000158464 (rank : 245)
Query Neighborhood Hits	812	Target Neighborhood Hits	512	Shared Neighborhood Hits	253
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CD2A1_HUMAN
NC score	0.618190 (rank : 193)	θ value	0.00035302 (rank : 256)
Query Neighborhood Hits	812	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

RAI14_MOUSE
NC score	0.602781 (rank : 194)	θ value	5.07402e-19 (rank : 36)
Query Neighborhood Hits	812	Target Neighborhood Hits	1505	Shared Neighborhood Hits	353
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR43_MOUSE
NC score	0.595983 (rank : 195)	θ value	0.00298849 (rank : 285)
Query Neighborhood Hits	812	Target Neighborhood Hits	214	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR18_HUMAN
NC score	0.595762 (rank : 196)	θ value	1.63604e-09 (rank : 128)
Query Neighborhood Hits	812	Target Neighborhood Hits	1106	Shared Neighborhood Hits	303
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR43_HUMAN
NC score	0.594303 (rank : 197)	θ value	0.0330416 (rank : 336)
Query Neighborhood Hits	812	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
NC score	0.592125 (rank : 198)	θ value	0.21417 (rank : 390)
Query Neighborhood Hits	812	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR45_HUMAN
NC score	0.588529 (rank : 199)	θ value	1.43324e-05 (rank : 212)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	187
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HECD1_HUMAN
NC score	0.585653 (rank : 200)	θ value	8.40245e-06 (rank : 206)
Query Neighborhood Hits	812	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

RIPK4_HUMAN
NC score	0.583064 (rank : 201)	θ value	1.98606e-31 (rank : 7)
Query Neighborhood Hits	812	Target Neighborhood Hits	1094	Shared Neighborhood Hits	342
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_HUMAN
NC score	0.583014 (rank : 202)	θ value	2.12685e-25 (rank : 12)
Query Neighborhood Hits	812	Target Neighborhood Hits	1075	Shared Neighborhood Hits	335
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ABTB2_HUMAN
NC score	0.579121 (rank : 203)	θ value	7.59969e-07 (rank : 178)
Query Neighborhood Hits	812	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
NC score	0.575468 (rank : 204)	θ value	4.92598e-06 (rank : 202)
Query Neighborhood Hits	812	Target Neighborhood Hits	1156	Shared Neighborhood Hits	397
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

IASPP_HUMAN
NC score	0.575222 (rank : 205)	θ value	0.000786445 (rank : 271)
Query Neighborhood Hits	812	Target Neighborhood Hits	688	Shared Neighborhood Hits	375
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP1_HUMAN
NC score	0.570717 (rank : 206)	θ value	4.1701e-05 (rank : 228)
Query Neighborhood Hits	812	Target Neighborhood Hits	956	Shared Neighborhood Hits	372
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ANKK1_MOUSE
NC score	0.568829 (rank : 207)	θ value	1.5242e-23 (rank : 15)
Query Neighborhood Hits	812	Target Neighborhood Hits	1072	Shared Neighborhood Hits	333
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

AN30A_HUMAN
NC score	0.568156 (rank : 208)	θ value	2.79066e-09 (rank : 132)
Query Neighborhood Hits	812	Target Neighborhood Hits	1119	Shared Neighborhood Hits	328
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

NUD12_MOUSE
NC score	0.567601 (rank : 209)	θ value	4.1701e-05 (rank : 231)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ABTB2_MOUSE
NC score	0.564902 (rank : 210)	θ value	5.44631e-05 (rank : 232)
Query Neighborhood Hits	812	Target Neighborhood Hits	414	Shared Neighborhood Hits	240
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP1_MOUSE
NC score	0.561977 (rank : 211)	θ value	1.43324e-05 (rank : 213)
Query Neighborhood Hits	812	Target Neighborhood Hits	1244	Shared Neighborhood Hits	451
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CLPB_HUMAN
NC score	0.558260 (rank : 212)	θ value	0.163984 (rank : 380)
Query Neighborhood Hits	812	Target Neighborhood Hits	265	Shared Neighborhood Hits	234
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR40_MOUSE
NC score	0.557761 (rank : 213)	θ value	0.163984 (rank : 378)
Query Neighborhood Hits	812	Target Neighborhood Hits	228	Shared Neighborhood Hits	211
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_HUMAN
NC score	0.557736 (rank : 214)	θ value	0.163984 (rank : 377)
Query Neighborhood Hits	812	Target Neighborhood Hits	224	Shared Neighborhood Hits	210
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ILK2_HUMAN
NC score	0.556484 (rank : 215)	θ value	2.69671e-12 (rank : 98)
Query Neighborhood Hits	812	Target Neighborhood Hits	848	Shared Neighborhood Hits	318
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

CENB5_HUMAN
NC score	0.540702 (rank : 216)	θ value	1.29631e-06 (rank : 184)
Query Neighborhood Hits	812	Target Neighborhood Hits	395	Shared Neighborhood Hits	268
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ILK1_HUMAN
NC score	0.539253 (rank : 217)	θ value	2.69671e-12 (rank : 97)
Query Neighborhood Hits	812	Target Neighborhood Hits	857	Shared Neighborhood Hits	318
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.538152 (rank : 218)	θ value	1.58096e-12 (rank : 95)
Query Neighborhood Hits	812	Target Neighborhood Hits	858	Shared Neighborhood Hits	318
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

TRPV6_MOUSE
NC score	0.535414 (rank : 219)	θ value	9.29e-05 (rank : 242)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	256
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

IASPP_MOUSE
NC score	0.535119 (rank : 220)	θ value	0.000602161 (rank : 266)
Query Neighborhood Hits	812	Target Neighborhood Hits	1024	Shared Neighborhood Hits	452
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUD12_HUMAN
NC score	0.533077 (rank : 221)	θ value	0.00134147 (rank : 279)
Query Neighborhood Hits	812	Target Neighborhood Hits	222	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASB14_HUMAN
NC score	0.530013 (rank : 222)	θ value	0.00134147 (rank : 274)
Query Neighborhood Hits	812	Target Neighborhood Hits	187	Shared Neighborhood Hits	176
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

AN13B_MOUSE
NC score	0.529560 (rank : 223)	θ value	1.87187e-05 (rank : 216)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	252
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CENB2_HUMAN
NC score	0.528887 (rank : 224)	θ value	7.1131e-05 (rank : 237)
Query Neighborhood Hits	812	Target Neighborhood Hits	425	Shared Neighborhood Hits	261
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

AN13B_HUMAN
NC score	0.528866 (rank : 225)	θ value	1.87187e-05 (rank : 215)
Query Neighborhood Hits	812	Target Neighborhood Hits	265	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

GLSL_HUMAN
NC score	0.528415 (rank : 226)	θ value	0.000270298 (rank : 255)
Query Neighborhood Hits	812	Target Neighborhood Hits	211	Shared Neighborhood Hits	204
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

CENB1_HUMAN
NC score	0.527805 (rank : 227)	θ value	0.0330416 (rank : 337)
Query Neighborhood Hits	812	Target Neighborhood Hits	383	Shared Neighborhood Hits	266
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ANKY1_HUMAN
NC score	0.527170 (rank : 228)	θ value	0.125558 (rank : 371)
Query Neighborhood Hits	812	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

GLSL_MOUSE
NC score	0.524856 (rank : 229)	θ value	2.44474e-05 (rank : 224)
Query Neighborhood Hits	812	Target Neighborhood Hits	212	Shared Neighborhood Hits	204
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13C_HUMAN
NC score	0.518118 (rank : 230)	θ value	0.00509761 (rank : 296)
Query Neighborhood Hits	812	Target Neighborhood Hits	241	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
NC score	0.507218 (rank : 231)	θ value	0.00665767 (rank : 298)
Query Neighborhood Hits	812	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT2_MOUSE
NC score	0.497580 (rank : 232)	θ value	0.00390308 (rank : 292)
Query Neighborhood Hits	812	Target Neighborhood Hits	323	Shared Neighborhood Hits	259
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TRPV5_MOUSE
NC score	0.492483 (rank : 233)	θ value	2.88788e-06 (rank : 192)
Query Neighborhood Hits	812	Target Neighborhood Hits	278	Shared Neighborhood Hits	248
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

UACA_HUMAN
NC score	0.490100 (rank : 234)	θ value	1.47974e-10 (rank : 114)
Query Neighborhood Hits	812	Target Neighborhood Hits	1622	Shared Neighborhood Hits	335
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

DDFL1_MOUSE
NC score	0.481497 (rank : 235)	θ value	3.77169e-06 (rank : 198)
Query Neighborhood Hits	812	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GLSK_HUMAN
NC score	0.480533 (rank : 236)	θ value	0.00134147 (rank : 276)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GIT1_MOUSE
NC score	0.478180 (rank : 237)	θ value	0.0252991 (rank : 330)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	252
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.477049 (rank : 238)	θ value	0.0252991 (rank : 329)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	251
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

CT012_MOUSE
NC score	0.472863 (rank : 239)	θ value	0.000461057 (rank : 261)
Query Neighborhood Hits	812	Target Neighborhood Hits	229	Shared Neighborhood Hits	184
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

TNI3K_HUMAN
NC score	0.472540 (rank : 240)	θ value	6.40375e-22 (rank : 23)
Query Neighborhood Hits	812	Target Neighborhood Hits	1084	Shared Neighborhood Hits	341
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.467012 (rank : 241)	θ value	7.0802e-21 (rank : 29)
Query Neighborhood Hits	812	Target Neighborhood Hits	1079	Shared Neighborhood Hits	340
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

AN13A_HUMAN
NC score	0.466298 (rank : 242)	θ value	0.000270298 (rank : 254)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

UACA_MOUSE
NC score	0.465078 (rank : 243)	θ value	3.64472e-09 (rank : 138)
Query Neighborhood Hits	812	Target Neighborhood Hits	1620	Shared Neighborhood Hits	333
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GIT2_HUMAN
NC score	0.461640 (rank : 244)	θ value	0.00665767 (rank : 301)
Query Neighborhood Hits	812	Target Neighborhood Hits	381	Shared Neighborhood Hits	251
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

TRPV6_HUMAN
NC score	0.451974 (rank : 245)	θ value	0.000461057 (rank : 262)
Query Neighborhood Hits	812	Target Neighborhood Hits	262	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

NOTC4_MOUSE
NC score	0.450790 (rank : 246)	θ value	9.90251e-15 (rank : 68)
Query Neighborhood Hits	812	Target Neighborhood Hits	872	Shared Neighborhood Hits	304
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV5_HUMAN
NC score	0.447612 (rank : 247)	θ value	0.00175202 (rank : 281)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

NOTC4_HUMAN
NC score	0.445781 (rank : 248)	θ value	3.40345e-15 (rank : 66)
Query Neighborhood Hits	812	Target Neighborhood Hits	905	Shared Neighborhood Hits	309
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR26_MOUSE
NC score	0.442136 (rank : 249)	θ value	1.69304e-06 (rank : 186)
Query Neighborhood Hits	812	Target Neighborhood Hits	1554	Shared Neighborhood Hits	331
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_MOUSE
NC score	0.438565 (rank : 250)	θ value	0.00665767 (rank : 297)
Query Neighborhood Hits	812	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CT012_HUMAN
NC score	0.436095 (rank : 251)	θ value	0.000786445 (rank : 267)
Query Neighborhood Hits	812	Target Neighborhood Hits	205	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

ANR26_HUMAN
NC score	0.423186 (rank : 252)	θ value	3.77169e-06 (rank : 196)
Query Neighborhood Hits	812	Target Neighborhood Hits	1614	Shared Neighborhood Hits	342
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DDEF2_HUMAN
NC score	0.421586 (rank : 253)	θ value	9.29e-05 (rank : 239)
Query Neighborhood Hits	812	Target Neighborhood Hits	599	Shared Neighborhood Hits	318
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.419061 (rank : 254)	θ value	9.29e-05 (rank : 240)
Query Neighborhood Hits	812	Target Neighborhood Hits	625	Shared Neighborhood Hits	323
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DAPK1_MOUSE
NC score	0.413103 (rank : 255)	θ value	2.43343e-21 (rank : 26)
Query Neighborhood Hits	812	Target Neighborhood Hits	1138	Shared Neighborhood Hits	341
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_MOUSE
NC score	0.406967 (rank : 256)	θ value	0.0113563 (rank : 313)
Query Neighborhood Hits	812	Target Neighborhood Hits	1333	Shared Neighborhood Hits	329
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_HUMAN
NC score	0.405842 (rank : 257)	θ value	0.21417 (rank : 396)
Query Neighborhood Hits	812	Target Neighborhood Hits	1103	Shared Neighborhood Hits	314
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DAPK1_HUMAN
NC score	0.405420 (rank : 258)	θ value	6.40375e-22 (rank : 22)
Query Neighborhood Hits	812	Target Neighborhood Hits	1130	Shared Neighborhood Hits	335
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC3_MOUSE
NC score	0.403989 (rank : 259)	θ value	4.0297e-08 (rank : 156)
Query Neighborhood Hits	812	Target Neighborhood Hits	975	Shared Neighborhood Hits	339
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.403136 (rank : 260)	θ value	5.26297e-08 (rank : 158)
Query Neighborhood Hits	812	Target Neighborhood Hits	1062	Shared Neighborhood Hits	354
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.397776 (rank : 261)	θ value	4.0297e-08 (rank : 154)
Query Neighborhood Hits	812	Target Neighborhood Hits	1113	Shared Neighborhood Hits	370
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.396089 (rank : 262)	θ value	1.17247e-07 (rank : 163)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	309
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.394701 (rank : 263)	θ value	4.0297e-08 (rank : 155)
Query Neighborhood Hits	812	Target Neighborhood Hits	1069	Shared Neighborhood Hits	347
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DDFL1_HUMAN
NC score	0.389814 (rank : 264)	θ value	0.00134147 (rank : 275)
Query Neighborhood Hits	812	Target Neighborhood Hits	353	Shared Neighborhood Hits	249
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_HUMAN
NC score	0.361240 (rank : 265)	θ value	0.163984 (rank : 383)
Query Neighborhood Hits	812	Target Neighborhood Hits	551	Shared Neighborhood Hits	223
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_MOUSE
NC score	0.352000 (rank : 266)	θ value	1.38821 (rank : 513)
Query Neighborhood Hits	812	Target Neighborhood Hits	531	Shared Neighborhood Hits	286
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.349902 (rank : 267)	θ value	0.813845 (rank : 470)
Query Neighborhood Hits	812	Target Neighborhood Hits	544	Shared Neighborhood Hits	291
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ANKZ1_MOUSE
NC score	0.347529 (rank : 268)	θ value	0.00665767 (rank : 299)
Query Neighborhood Hits	812	Target Neighborhood Hits	208	Shared Neighborhood Hits	156
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

DGKZ_MOUSE
NC score	0.345673 (rank : 269)	θ value	0.00869519 (rank : 304)
Query Neighborhood Hits	812	Target Neighborhood Hits	542	Shared Neighborhood Hits	208
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
NC score	0.341761 (rank : 270)	θ value	0.0330416 (rank : 338)
Query Neighborhood Hits	812	Target Neighborhood Hits	609	Shared Neighborhood Hits	223
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CENG2_HUMAN
NC score	0.340287 (rank : 271)	θ value	0.47712 (rank : 437)
Query Neighborhood Hits	812	Target Neighborhood Hits	471	Shared Neighborhood Hits	254
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

DDEF1_MOUSE
NC score	0.338158 (rank : 272)	θ value	9.29e-05 (rank : 238)
Query Neighborhood Hits	812	Target Neighborhood Hits	592	Shared Neighborhood Hits	275
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CENG2_MOUSE
NC score	0.337401 (rank : 273)	θ value	0.47712 (rank : 438)
Query Neighborhood Hits	812	Target Neighborhood Hits	463	Shared Neighborhood Hits	251
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

NOTC1_MOUSE
NC score	0.335419 (rank : 274)	θ value	0.000786445 (rank : 273)
Query Neighborhood Hits	812	Target Neighborhood Hits	916	Shared Neighborhood Hits	293
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKZ1_HUMAN
NC score	0.324503 (rank : 275)	θ value	1.06291 (rank : 482)
Query Neighborhood Hits	812	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

CENG3_MOUSE
NC score	0.314315 (rank : 276)	θ value	0.00035302 (rank : 258)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	238
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.314034 (rank : 277)	θ value	0.00035302 (rank : 257)
Query Neighborhood Hits	812	Target Neighborhood Hits	455	Shared Neighborhood Hits	237
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

IKBL_HUMAN
NC score	0.307363 (rank : 278)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.301177 (rank : 279)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	812	Target Neighborhood Hits	196	Shared Neighborhood Hits	142
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CLR59_HUMAN
NC score	0.298285 (rank : 280)	θ value	0.0148317 (rank : 315)
Query Neighborhood Hits	812	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ABTB1_MOUSE
NC score	0.283357 (rank : 281)	θ value	2.36792 (rank : 571)
Query Neighborhood Hits	812	Target Neighborhood Hits	349	Shared Neighborhood Hits	178
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ANKR9_MOUSE
NC score	0.255797 (rank : 282)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	812	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_MOUSE
NC score	0.249738 (rank : 283)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

RSNL2_HUMAN
NC score	0.244717 (rank : 284)	θ value	0.365318 (rank : 424)
Query Neighborhood Hits	812	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ABTB1_HUMAN
NC score	0.239047 (rank : 285)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV1_MOUSE
NC score	0.231232 (rank : 286)	θ value	4.03905 (rank : 688)
Query Neighborhood Hits	812	Target Neighborhood Hits	189	Shared Neighborhood Hits	156
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV3_HUMAN
NC score	0.221272 (rank : 287)	θ value	3.0926 (rank : 646)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

BAT4_HUMAN
NC score	0.218944 (rank : 288)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	812	Target Neighborhood Hits	157	Shared Neighborhood Hits	114
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

TRPV3_MOUSE
NC score	0.218634 (rank : 289)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	812	Target Neighborhood Hits	188	Shared Neighborhood Hits	133
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_HUMAN
NC score	0.209758 (rank : 290)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	812	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_HUMAN
NC score	0.208227 (rank : 291)	θ value	0.0736092 (rank : 361)
Query Neighborhood Hits	812	Target Neighborhood Hits	130	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CMTA1_HUMAN
NC score	0.205856 (rank : 292)	θ value	0.62314 (rank : 455)
Query Neighborhood Hits	812	Target Neighborhood Hits	217	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

ANKR9_HUMAN
NC score	0.205398 (rank : 293)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

RSNL2_MOUSE
NC score	0.201648 (rank : 294)	θ value	8.99809 (rank : 800)
Query Neighborhood Hits	812	Target Neighborhood Hits	129	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CMTA2_HUMAN
NC score	0.178384 (rank : 295)	θ value	1.81305 (rank : 543)
Query Neighborhood Hits	812	Target Neighborhood Hits	199	Shared Neighborhood Hits	123
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV2_MOUSE
NC score	0.165938 (rank : 296)	θ value	0.0193708 (rank : 327)
Query Neighborhood Hits	812	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CMTA2_MOUSE
NC score	0.165759 (rank : 297)	θ value	1.06291 (rank : 486)
Query Neighborhood Hits	812	Target Neighborhood Hits	216	Shared Neighborhood Hits	117
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

PRP1_HUMAN
NC score	0.148758 (rank : 298)	θ value	6.88961 (rank : 753)
Query Neighborhood Hits	812	Target Neighborhood Hits	385	Shared Neighborhood Hits	137
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WASIP_HUMAN
NC score	0.142472 (rank : 299)	θ value	5.27518 (rank : 728)
Query Neighborhood Hits	812	Target Neighborhood Hits	458	Shared Neighborhood Hits	153
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRB4S_HUMAN
NC score	0.140747 (rank : 300)	θ value	1.38821 (rank : 528)
Query Neighborhood Hits	812	Target Neighborhood Hits	330	Shared Neighborhood Hits	128
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP2_MOUSE
NC score	0.138211 (rank : 301)	θ value	4.03905 (rank : 676)
Query Neighborhood Hits	812	Target Neighborhood Hits	347	Shared Neighborhood Hits	125
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NACAM_MOUSE
NC score	0.137465 (rank : 302)	θ value	2.44474e-05 (rank : 225)
Query Neighborhood Hits	812	Target Neighborhood Hits	1866	Shared Neighborhood Hits	315
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
NC score	0.134108 (rank : 303)	θ value	0.00228821 (rank : 283)
Query Neighborhood Hits	812	Target Neighborhood Hits	1582	Shared Neighborhood Hits	305
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LRRK1_MOUSE
NC score	0.132937 (rank : 304)	θ value	5.81887e-07 (rank : 177)
Query Neighborhood Hits	812	Target Neighborhood Hits	1267	Shared Neighborhood Hits	174
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MUC1_HUMAN
NC score	0.132565 (rank : 305)	θ value	6.41864e-14 (rank : 80)
Query Neighborhood Hits	812	Target Neighborhood Hits	975	Shared Neighborhood Hits	210
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PRRT3_HUMAN
NC score	0.132560 (rank : 306)	θ value	1.29631e-06 (rank : 185)
Query Neighborhood Hits	812	Target Neighborhood Hits	998	Shared Neighborhood Hits	238
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PRB3_HUMAN
NC score	0.130713 (rank : 307)	θ value	0.813845 (rank : 474)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	122
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SASH1_MOUSE
NC score	0.128168 (rank : 308)	θ value	0.00869519 (rank : 306)
Query Neighborhood Hits	812	Target Neighborhood Hits	263	Shared Neighborhood Hits	103
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

ANKF1_HUMAN
NC score	0.126931 (rank : 309)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	812	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

WASIP_MOUSE
NC score	0.125921 (rank : 310)	θ value	5.27518 (rank : 729)
Query Neighborhood Hits	812	Target Neighborhood Hits	392	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

TRPC6_HUMAN
NC score	0.125345 (rank : 311)	θ value	0.279714 (rank : 410)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TAF4_HUMAN
NC score	0.124854 (rank : 312)	θ value	0.0563607 (rank : 347)
Query Neighborhood Hits	812	Target Neighborhood Hits	687	Shared Neighborhood Hits	169
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

BSN_MOUSE
NC score	0.124447 (rank : 313)	θ value	0.000602161 (rank : 265)
Query Neighborhood Hits	812	Target Neighborhood Hits	2057	Shared Neighborhood Hits	347
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SASH1_HUMAN
NC score	0.123200 (rank : 314)	θ value	0.00298849 (rank : 289)
Query Neighborhood Hits	812	Target Neighborhood Hits	292	Shared Neighborhood Hits	120
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SRRM1_MOUSE
NC score	0.122829 (rank : 315)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	812	Target Neighborhood Hits	966	Shared Neighborhood Hits	204
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NCOA6_HUMAN
NC score	0.120387 (rank : 316)	θ value	0.000786445 (rank : 272)
Query Neighborhood Hits	812	Target Neighborhood Hits	1202	Shared Neighborhood Hits	250
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BAT2_HUMAN
NC score	0.119432 (rank : 317)	θ value	1.06291 (rank : 483)
Query Neighborhood Hits	812	Target Neighborhood Hits	931	Shared Neighborhood Hits	239
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SHAN2_MOUSE
NC score	0.118215 (rank : 318)	θ value	0.0193708 (rank : 323)
Query Neighborhood Hits	812	Target Neighborhood Hits	446	Shared Neighborhood Hits	134
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PRR12_HUMAN
NC score	0.117467 (rank : 319)	θ value	4.03905 (rank : 677)
Query Neighborhood Hits	812	Target Neighborhood Hits	460	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SON_HUMAN
NC score	0.117159 (rank : 320)	θ value	1.53129e-07 (rank : 164)
Query Neighborhood Hits	812	Target Neighborhood Hits	1568	Shared Neighborhood Hits	286
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MDC1_HUMAN
NC score	0.117157 (rank : 321)	θ value	0.00665767 (rank : 302)
Query Neighborhood Hits	812	Target Neighborhood Hits	1446	Shared Neighborhood Hits	241
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GSCR1_HUMAN
NC score	0.116519 (rank : 322)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	812	Target Neighborhood Hits	674	Shared Neighborhood Hits	191
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

TRPV4_HUMAN
NC score	0.115581 (rank : 323)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	812	Target Neighborhood Hits	150	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

WIRE_MOUSE
NC score	0.114889 (rank : 324)	θ value	0.365318 (rank : 431)
Query Neighborhood Hits	812	Target Neighborhood Hits	310	Shared Neighborhood Hits	113
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

BSN_HUMAN
NC score	0.112761 (rank : 325)	θ value	0.0193708 (rank : 316)
Query Neighborhood Hits	812	Target Neighborhood Hits	1537	Shared Neighborhood Hits	282
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SHAN2_HUMAN
NC score	0.112174 (rank : 326)	θ value	0.0431538 (rank : 343)
Query Neighborhood Hits	812	Target Neighborhood Hits	346	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

MAGE1_HUMAN
NC score	0.110624 (rank : 327)	θ value	2.79066e-09 (rank : 136)
Query Neighborhood Hits	812	Target Neighborhood Hits	1389	Shared Neighborhood Hits	285
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SRRM2_MOUSE
NC score	0.110047 (rank : 328)	θ value	2.36792 (rank : 592)
Query Neighborhood Hits	812	Target Neighborhood Hits	1470	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRPC3_HUMAN
NC score	0.110006 (rank : 329)	θ value	0.00869519 (rank : 308)
Query Neighborhood Hits	812	Target Neighborhood Hits	137	Shared Neighborhood Hits	82
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

NCOA6_MOUSE
NC score	0.109993 (rank : 330)	θ value	3.0926 (rank : 629)
Query Neighborhood Hits	812	Target Neighborhood Hits	1076	Shared Neighborhood Hits	240
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

LRRK1_HUMAN
NC score	0.109599 (rank : 331)	θ value	5.44631e-05 (rank : 236)
Query Neighborhood Hits	812	Target Neighborhood Hits	1237	Shared Neighborhood Hits	149
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

WIRE_HUMAN
NC score	0.109584 (rank : 332)	θ value	0.365318 (rank : 430)
Query Neighborhood Hits	812	Target Neighborhood Hits	329	Shared Neighborhood Hits	110
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SRRM1_HUMAN
NC score	0.109530 (rank : 333)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	812	Target Neighborhood Hits	690	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
NC score	0.109483 (rank : 334)	θ value	1.06291 (rank : 506)
Query Neighborhood Hits	812	Target Neighborhood Hits	1296	Shared Neighborhood Hits	230
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

EPHB6_HUMAN
NC score	0.108344 (rank : 335)	θ value	0.00869519 (rank : 305)
Query Neighborhood Hits	812	Target Neighborhood Hits	912	Shared Neighborhood Hits	87
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
NC score	0.108086 (rank : 336)	θ value	0.00298849 (rank : 287)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	86
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA5_HUMAN
NC score	0.107927 (rank : 337)	θ value	2.88788e-06 (rank : 190)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA6_HUMAN
NC score	0.107344 (rank : 338)	θ value	0.000786445 (rank : 268)
Query Neighborhood Hits	812	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MBD6_HUMAN
NC score	0.107110 (rank : 339)	θ value	8.99809 (rank : 793)
Query Neighborhood Hits	812	Target Neighborhood Hits	349	Shared Neighborhood Hits	122
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CEND3_HUMAN
NC score	0.106947 (rank : 340)	θ value	0.0431538 (rank : 340)
Query Neighborhood Hits	812	Target Neighborhood Hits	275	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

SARM1_MOUSE
NC score	0.106599 (rank : 341)	θ value	0.0193708 (rank : 322)
Query Neighborhood Hits	812	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

MUC7_HUMAN
NC score	0.106574 (rank : 342)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	812	Target Neighborhood Hits	538	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TRPV4_MOUSE
NC score	0.106330 (rank : 343)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	79
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

EPHA7_HUMAN
NC score	0.105893 (rank : 344)	θ value	1.09739e-05 (rank : 208)
Query Neighborhood Hits	812	Target Neighborhood Hits	1053	Shared Neighborhood Hits	98
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA6_MOUSE
NC score	0.105806 (rank : 345)	θ value	0.00298849 (rank : 286)
Query Neighborhood Hits	812	Target Neighborhood Hits	946	Shared Neighborhood Hits	83
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

PCLO_MOUSE
NC score	0.105755 (rank : 346)	θ value	0.0193708 (rank : 320)
Query Neighborhood Hits	812	Target Neighborhood Hits	2275	Shared Neighborhood Hits	354
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EPHB3_HUMAN
NC score	0.105721 (rank : 347)	θ value	6.43352e-06 (rank : 204)
Query Neighborhood Hits	812	Target Neighborhood Hits	996	Shared Neighborhood Hits	91
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA1_MOUSE
NC score	0.105607 (rank : 348)	θ value	1.09739e-05 (rank : 207)
Query Neighborhood Hits	812	Target Neighborhood Hits	958	Shared Neighborhood Hits	93
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA1_HUMAN
NC score	0.105498 (rank : 349)	θ value	1.87187e-05 (rank : 218)
Query Neighborhood Hits	812	Target Neighborhood Hits	997	Shared Neighborhood Hits	98
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

BAT2_MOUSE
NC score	0.105193 (rank : 350)	θ value	1.06291 (rank : 484)
Query Neighborhood Hits	812	Target Neighborhood Hits	947	Shared Neighborhood Hits	242
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EPHA7_MOUSE
NC score	0.104903 (rank : 351)	θ value	2.44474e-05 (rank : 223)
Query Neighborhood Hits	812	Target Neighborhood Hits	1025	Shared Neighborhood Hits	90
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

ATN1_HUMAN
NC score	0.104739 (rank : 352)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	812	Target Neighborhood Hits	676	Shared Neighborhood Hits	149
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

EPHA2_MOUSE
NC score	0.104739 (rank : 353)	θ value	1.69304e-06 (rank : 187)
Query Neighborhood Hits	812	Target Neighborhood Hits	1020	Shared Neighborhood Hits	88
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHB4_HUMAN
NC score	0.104706 (rank : 354)	θ value	5.44631e-05 (rank : 235)
Query Neighborhood Hits	812	Target Neighborhood Hits	1056	Shared Neighborhood Hits	99
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHA2_HUMAN
NC score	0.104685 (rank : 355)	θ value	9.92553e-07 (rank : 180)
Query Neighborhood Hits	812	Target Neighborhood Hits	1021	Shared Neighborhood Hits	89
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

PRG4_HUMAN
NC score	0.104672 (rank : 356)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	812	Target Neighborhood Hits	764	Shared Neighborhood Hits	162
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

EPHB3_MOUSE
NC score	0.104501 (rank : 357)	θ value	1.43324e-05 (rank : 214)
Query Neighborhood Hits	812	Target Neighborhood Hits	996	Shared Neighborhood Hits	88
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB2_HUMAN
NC score	0.104465 (rank : 358)	θ value	0.00020696 (rank : 251)
Query Neighborhood Hits	812	Target Neighborhood Hits	983	Shared Neighborhood Hits	89
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHAA_HUMAN
NC score	0.104015 (rank : 359)	θ value	0.00390308 (rank : 291)
Query Neighborhood Hits	812	Target Neighborhood Hits	960	Shared Neighborhood Hits	87
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

RGS3_MOUSE
NC score	0.103638 (rank : 360)	θ value	9.29e-05 (rank : 241)
Query Neighborhood Hits	812	Target Neighborhood Hits	1621	Shared Neighborhood Hits	297
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MDC1_MOUSE
NC score	0.103542 (rank : 361)	θ value	1.38821 (rank : 526)
Query Neighborhood Hits	812	Target Neighborhood Hits	998	Shared Neighborhood Hits	198
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

EPHB4_MOUSE
NC score	0.103530 (rank : 362)	θ value	0.000121331 (rank : 244)
Query Neighborhood Hits	812	Target Neighborhood Hits	1013	Shared Neighborhood Hits	91
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHA8_MOUSE
NC score	0.103330 (rank : 363)	θ value	0.000786445 (rank : 270)
Query Neighborhood Hits	812	Target Neighborhood Hits	969	Shared Neighborhood Hits	84
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

PCLO_HUMAN
NC score	0.103149 (rank : 364)	θ value	5.27518 (rank : 715)
Query Neighborhood Hits	812	Target Neighborhood Hits	2046	Shared Neighborhood Hits	316
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

EPHB2_MOUSE
NC score	0.103067 (rank : 365)	θ value	0.00020696 (rank : 252)
Query Neighborhood Hits	812	Target Neighborhood Hits	982	Shared Neighborhood Hits	89
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

BASP_MOUSE
NC score	0.102410 (rank : 366)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

EPHB1_HUMAN
NC score	0.101827 (rank : 367)	θ value	5.44631e-05 (rank : 234)
Query Neighborhood Hits	812	Target Neighborhood Hits	988	Shared Neighborhood Hits	90
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

GRIN1_HUMAN
NC score	0.101498 (rank : 368)	θ value	0.00020696 (rank : 253)
Query Neighborhood Hits	812	Target Neighborhood Hits	681	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TARSH_HUMAN
NC score	0.101389 (rank : 369)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	812	Target Neighborhood Hits	768	Shared Neighborhood Hits	186
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

EPHA8_HUMAN
NC score	0.101385 (rank : 370)	θ value	0.000786445 (rank : 269)
Query Neighborhood Hits	812	Target Neighborhood Hits	956	Shared Neighborhood Hits	83
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

CEND3_MOUSE
NC score	0.100515 (rank : 371)	θ value	0.0961366 (rank : 363)
Query Neighborhood Hits	812	Target Neighborhood Hits	228	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

TRPC3_MOUSE
NC score	0.100142 (rank : 372)	θ value	0.0736092 (rank : 360)
Query Neighborhood Hits	812	Target Neighborhood Hits	131	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

BCL9_HUMAN
NC score	0.099843 (rank : 373)	θ value	0.365318 (rank : 413)
Query Neighborhood Hits	812	Target Neighborhood Hits	1008	Shared Neighborhood Hits	233
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EPHA4_MOUSE
NC score	0.099741 (rank : 374)	θ value	0.0113563 (rank : 310)
Query Neighborhood Hits	812	Target Neighborhood Hits	982	Shared Neighborhood Hits	85
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA4_HUMAN
NC score	0.099530 (rank : 375)	θ value	0.0113563 (rank : 309)
Query Neighborhood Hits	812	Target Neighborhood Hits	975	Shared Neighborhood Hits	84
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA5_MOUSE
NC score	0.098367 (rank : 376)	θ value	1.87187e-05 (rank : 219)
Query Neighborhood Hits	812	Target Neighborhood Hits	950	Shared Neighborhood Hits	86
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

SON_MOUSE
NC score	0.098128 (rank : 377)	θ value	0.163984 (rank : 387)
Query Neighborhood Hits	812	Target Neighborhood Hits	957	Shared Neighborhood Hits	183
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MLL3_HUMAN
NC score	0.097766 (rank : 378)	θ value	0.0431538 (rank : 342)
Query Neighborhood Hits	812	Target Neighborhood Hits	1644	Shared Neighborhood Hits	271
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TRPC6_MOUSE
NC score	0.097413 (rank : 379)	θ value	2.36792 (rank : 595)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	92
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

BCL9_MOUSE
NC score	0.097366 (rank : 380)	θ value	3.0926 (rank : 606)
Query Neighborhood Hits	812	Target Neighborhood Hits	770	Shared Neighborhood Hits	200
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

TRPC7_HUMAN
NC score	0.097130 (rank : 381)	θ value	0.0252991 (rank : 335)
Query Neighborhood Hits	812	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

MLL3_MOUSE
NC score	0.096863 (rank : 382)	θ value	0.0563607 (rank : 346)
Query Neighborhood Hits	812	Target Neighborhood Hits	1399	Shared Neighborhood Hits	244
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RERE_MOUSE
NC score	0.096098 (rank : 383)	θ value	0.0736092 (rank : 358)
Query Neighborhood Hits	812	Target Neighborhood Hits	785	Shared Neighborhood Hits	180
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TRPC7_MOUSE
NC score	0.095459 (rank : 384)	θ value	0.0961366 (rank : 370)
Query Neighborhood Hits	812	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

PRG4_MOUSE
NC score	0.094431 (rank : 385)	θ value	0.163984 (rank : 385)
Query Neighborhood Hits	812	Target Neighborhood Hits	624	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SARM1_HUMAN
NC score	0.094333 (rank : 386)	θ value	0.0193708 (rank : 321)
Query Neighborhood Hits	812	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

CN155_HUMAN
NC score	0.092987 (rank : 387)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	812	Target Neighborhood Hits	385	Shared Neighborhood Hits	98
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

RERE_HUMAN
NC score	0.092864 (rank : 388)	θ value	0.365318 (rank : 423)
Query Neighborhood Hits	812	Target Neighborhood Hits	779	Shared Neighborhood Hits	175
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

PRP5_HUMAN
NC score	0.090648 (rank : 389)	θ value	2.36792 (rank : 587)
Query Neighborhood Hits	812	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

TCGAP_HUMAN
NC score	0.090547 (rank : 390)	θ value	0.00869519 (rank : 307)
Query Neighborhood Hits	812	Target Neighborhood Hits	872	Shared Neighborhood Hits	230
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

EPHA3_HUMAN
NC score	0.089860 (rank : 391)	θ value	2.36792 (rank : 577)
Query Neighborhood Hits	812	Target Neighborhood Hits	1005	Shared Neighborhood Hits	77
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

WBP11_MOUSE
NC score	0.089820 (rank : 392)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	812	Target Neighborhood Hits	362	Shared Neighborhood Hits	108
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

EPHA3_MOUSE
NC score	0.089635 (rank : 393)	θ value	3.0926 (rank : 615)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	76
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

SYN1_HUMAN
NC score	0.089071 (rank : 394)	θ value	0.365318 (rank : 427)
Query Neighborhood Hits	812	Target Neighborhood Hits	419	Shared Neighborhood Hits	151
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SAM14_MOUSE
NC score	0.088572 (rank : 395)	θ value	0.0736092 (rank : 359)
Query Neighborhood Hits	812	Target Neighborhood Hits	91	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

MLL2_HUMAN
NC score	0.088390 (rank : 396)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	812	Target Neighborhood Hits	1788	Shared Neighborhood Hits	284
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

WBP11_HUMAN
NC score	0.088192 (rank : 397)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	812	Target Neighborhood Hits	354	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CEND1_HUMAN
NC score	0.087625 (rank : 398)	θ value	0.47712 (rank : 436)
Query Neighborhood Hits	812	Target Neighborhood Hits	284	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MUCDL_HUMAN
NC score	0.087267 (rank : 399)	θ value	0.0736092 (rank : 356)
Query Neighborhood Hits	812	Target Neighborhood Hits	777	Shared Neighborhood Hits	189
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NFH_MOUSE
NC score	0.087252 (rank : 400)	θ value	8.97725e-08 (rank : 161)
Query Neighborhood Hits	812	Target Neighborhood Hits	2247	Shared Neighborhood Hits	291
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CPSF6_MOUSE
NC score	0.086021 (rank : 401)	θ value	3.0926 (rank : 612)
Query Neighborhood Hits	812	Target Neighborhood Hits	356	Shared Neighborhood Hits	111
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

BASP_HUMAN
NC score	0.085740 (rank : 402)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	812	Target Neighborhood Hits	321	Shared Neighborhood Hits	75
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN032_HUMAN
NC score	0.085409 (rank : 403)	θ value	8.99809 (rank : 772)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CPSF6_HUMAN
NC score	0.085237 (rank : 404)	θ value	3.0926 (rank : 611)
Query Neighborhood Hits	812	Target Neighborhood Hits	359	Shared Neighborhood Hits	108
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

GRIN1_MOUSE
NC score	0.084777 (rank : 405)	θ value	1.06291 (rank : 497)
Query Neighborhood Hits	812	Target Neighborhood Hits	337	Shared Neighborhood Hits	98
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K1543_MOUSE
NC score	0.084613 (rank : 406)	θ value	0.21417 (rank : 391)
Query Neighborhood Hits	812	Target Neighborhood Hits	497	Shared Neighborhood Hits	134
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

GGN_MOUSE
NC score	0.084613 (rank : 407)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	812	Target Neighborhood Hits	311	Shared Neighborhood Hits	102
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SYN1_MOUSE
NC score	0.084552 (rank : 408)	θ value	1.06291 (rank : 507)
Query Neighborhood Hits	812	Target Neighborhood Hits	363	Shared Neighborhood Hits	129
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

RAPH1_HUMAN
NC score	0.084518 (rank : 409)	θ value	8.99809 (rank : 798)
Query Neighborhood Hits	812	Target Neighborhood Hits	593	Shared Neighborhood Hits	163
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SAM14_HUMAN
NC score	0.084409 (rank : 410)	θ value	0.365318 (rank : 425)
Query Neighborhood Hits	812	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

CU081_HUMAN
NC score	0.084361 (rank : 411)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	812	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

SET1A_HUMAN
NC score	0.084344 (rank : 412)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	812	Target Neighborhood Hits	690	Shared Neighborhood Hits	144
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

K1802_MOUSE
NC score	0.084291 (rank : 413)	θ value	0.00390308 (rank : 293)
Query Neighborhood Hits	812	Target Neighborhood Hits	1596	Shared Neighborhood Hits	243
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PI5PA_HUMAN
NC score	0.084081 (rank : 414)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	812	Target Neighborhood Hits	749	Shared Neighborhood Hits	210
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CBP_MOUSE
NC score	0.084020 (rank : 415)	θ value	0.47712 (rank : 435)
Query Neighborhood Hits	812	Target Neighborhood Hits	1051	Shared Neighborhood Hits	232
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TARA_HUMAN
NC score	0.082701 (rank : 416)	θ value	0.00390308 (rank : 295)
Query Neighborhood Hits	812	Target Neighborhood Hits	1626	Shared Neighborhood Hits	248
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MARCS_HUMAN
NC score	0.082595 (rank : 417)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

TAU_MOUSE
NC score	0.082535 (rank : 418)	θ value	0.00228821 (rank : 284)
Query Neighborhood Hits	812	Target Neighborhood Hits	502	Shared Neighborhood Hits	127
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CN032_MOUSE
NC score	0.082290 (rank : 419)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	812	Target Neighborhood Hits	233	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

TCOF_HUMAN
NC score	0.082274 (rank : 420)	θ value	5.27518 (rank : 723)
Query Neighborhood Hits	812	Target Neighborhood Hits	543	Shared Neighborhood Hits	118
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CEND1_MOUSE
NC score	0.081867 (rank : 421)	θ value	0.813845 (rank : 469)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

DGKD_HUMAN
NC score	0.081720 (rank : 422)	θ value	0.47712 (rank : 444)
Query Neighborhood Hits	812	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

CSF1_HUMAN
NC score	0.081615 (rank : 423)	θ value	0.00390308 (rank : 290)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

YLPM1_HUMAN
NC score	0.081233 (rank : 424)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	812	Target Neighborhood Hits	670	Shared Neighborhood Hits	165
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MUC13_MOUSE
NC score	0.081160 (rank : 425)	θ value	5.27518 (rank : 713)
Query Neighborhood Hits	812	Target Neighborhood Hits	447	Shared Neighborhood Hits	95
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NOLC1_HUMAN
NC score	0.081093 (rank : 426)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	812	Target Neighborhood Hits	452	Shared Neighborhood Hits	95
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TAU_HUMAN
NC score	0.080939 (rank : 427)	θ value	0.47712 (rank : 452)
Query Neighborhood Hits	812	Target Neighborhood Hits	448	Shared Neighborhood Hits	131
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCOF_MOUSE
NC score	0.080853 (rank : 428)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	812	Target Neighborhood Hits	471	Shared Neighborhood Hits	97
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

YLPM1_MOUSE
NC score	0.080140 (rank : 429)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	812	Target Neighborhood Hits	505	Shared Neighborhood Hits	125
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

NU214_HUMAN
NC score	0.079904 (rank : 430)	θ value	4.03905 (rank : 673)
Query Neighborhood Hits	812	Target Neighborhood Hits	657	Shared Neighborhood Hits	133
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

LAD1_MOUSE
NC score	0.079894 (rank : 431)	θ value	0.21417 (rank : 392)
Query Neighborhood Hits	812	Target Neighborhood Hits	391	Shared Neighborhood Hits	85
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MARCS_MOUSE
NC score	0.079349 (rank : 432)	θ value	1.81305 (rank : 553)
Query Neighborhood Hits	812	Target Neighborhood Hits	227	Shared Neighborhood Hits	64
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

S23IP_MOUSE
NC score	0.079112 (rank : 433)	θ value	0.47712 (rank : 450)
Query Neighborhood Hits	812	Target Neighborhood Hits	363	Shared Neighborhood Hits	110
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ENAH_MOUSE
NC score	0.079050 (rank : 434)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	812	Target Neighborhood Hits	919	Shared Neighborhood Hits	176
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CIC_HUMAN
NC score	0.078830 (rank : 435)	θ value	6.88961 (rank : 736)
Query Neighborhood Hits	812	Target Neighborhood Hits	992	Shared Neighborhood Hits	241
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CK024_HUMAN
NC score	0.078441 (rank : 436)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	812	Target Neighborhood Hits	408	Shared Neighborhood Hits	107
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

RGS3_HUMAN
NC score	0.078328 (rank : 437)	θ value	0.00298849 (rank : 288)
Query Neighborhood Hits	812	Target Neighborhood Hits	1375	Shared Neighborhood Hits	247
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MISS_MOUSE
NC score	0.078165 (rank : 438)	θ value	0.0431538 (rank : 341)
Query Neighborhood Hits	812	Target Neighborhood Hits	444	Shared Neighborhood Hits	128
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

ALEX_HUMAN
NC score	0.077945 (rank : 439)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	812	Target Neighborhood Hits	361	Shared Neighborhood Hits	101
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CBP_HUMAN
NC score	0.077885 (rank : 440)	θ value	4.03905 (rank : 652)
Query Neighborhood Hits	812	Target Neighborhood Hits	941	Shared Neighborhood Hits	203
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ARI1A_HUMAN
NC score	0.077791 (rank : 441)	θ value	5.27518 (rank : 693)
Query Neighborhood Hits	812	Target Neighborhood Hits	787	Shared Neighborhood Hits	194
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

SLY_MOUSE
NC score	0.077629 (rank : 442)	θ value	1.81305 (rank : 562)
Query Neighborhood Hits	812	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

TGON2_HUMAN
NC score	0.077550 (rank : 443)	θ value	0.0252991 (rank : 333)
Query Neighborhood Hits	812	Target Neighborhood Hits	1037	Shared Neighborhood Hits	164
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRPC5_MOUSE
NC score	0.077417 (rank : 444)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	812	Target Neighborhood Hits	124	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

PRPE_HUMAN
NC score	0.077391 (rank : 445)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	812	Target Neighborhood Hits	44	Shared Neighborhood Hits	26
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

CS016_HUMAN
NC score	0.077063 (rank : 446)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	812	Target Neighborhood Hits	310	Shared Neighborhood Hits	99
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SAMN1_HUMAN
NC score	0.077000 (rank : 447)	θ value	1.81305 (rank : 560)
Query Neighborhood Hits	812	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

FMNL_HUMAN
NC score	0.076178 (rank : 448)	θ value	0.00665767 (rank : 300)
Query Neighborhood Hits	812	Target Neighborhood Hits	529	Shared Neighborhood Hits	126
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TRPC5_HUMAN
NC score	0.075938 (rank : 449)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	812	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

RP1L1_HUMAN
NC score	0.075575 (rank : 450)	θ value	0.813845 (rank : 475)
Query Neighborhood Hits	812	Target Neighborhood Hits	1072	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SAMN1_MOUSE
NC score	0.075298 (rank : 451)	θ value	8.99809 (rank : 801)
Query Neighborhood Hits	812	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

TXND2_HUMAN
NC score	0.075298 (rank : 452)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	812	Target Neighborhood Hits	793	Shared Neighborhood Hits	126
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DIDO1_HUMAN
NC score	0.075128 (rank : 453)	θ value	0.365318 (rank : 416)
Query Neighborhood Hits	812	Target Neighborhood Hits	960	Shared Neighborhood Hits	200
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

OGFR_MOUSE
NC score	0.075047 (rank : 454)	θ value	0.0961366 (rank : 366)
Query Neighborhood Hits	812	Target Neighborhood Hits	584	Shared Neighborhood Hits	114
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

MUC1_MOUSE
NC score	0.074990 (rank : 455)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	812	Target Neighborhood Hits	388	Shared Neighborhood Hits	73
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CJ078_MOUSE
NC score	0.074897 (rank : 456)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	812	Target Neighborhood Hits	559	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MLL4_HUMAN
NC score	0.074678 (rank : 457)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	812	Target Neighborhood Hits	722	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SF3A2_MOUSE
NC score	0.074279 (rank : 458)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	812	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CS007_MOUSE
NC score	0.073921 (rank : 459)	θ value	8.99809 (rank : 779)
Query Neighborhood Hits	812	Target Neighborhood Hits	464	Shared Neighborhood Hits	122
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

STAC_MOUSE
NC score	0.073847 (rank : 460)	θ value	0.0193708 (rank : 324)
Query Neighborhood Hits	812	Target Neighborhood Hits	268	Shared Neighborhood Hits	67
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

MUC2_HUMAN
NC score	0.073583 (rank : 461)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	153
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

STAC_HUMAN
NC score	0.073310 (rank : 462)	θ value	0.0252991 (rank : 332)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SNPC4_HUMAN
NC score	0.073089 (rank : 463)	θ value	2.36792 (rank : 591)
Query Neighborhood Hits	812	Target Neighborhood Hits	589	Shared Neighborhood Hits	166
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CABIN_HUMAN
NC score	0.072948 (rank : 464)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	812	Target Neighborhood Hits	490	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

GGN_HUMAN
NC score	0.072512 (rank : 465)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	91
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

BCAR1_HUMAN
NC score	0.072423 (rank : 466)	θ value	1.81305 (rank : 540)
Query Neighborhood Hits	812	Target Neighborhood Hits	554	Shared Neighborhood Hits	152
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

LIPB2_MOUSE
NC score	0.072376 (rank : 467)	θ value	0.0193708 (rank : 318)
Query Neighborhood Hits	812	Target Neighborhood Hits	570	Shared Neighborhood Hits	69
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

TRPC4_MOUSE
NC score	0.072313 (rank : 468)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	812	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.072270 (rank : 469)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	812	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

STAM1_MOUSE
NC score	0.072200 (rank : 470)	θ value	0.0193708 (rank : 326)
Query Neighborhood Hits	812	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

BAT3_MOUSE
NC score	0.072090 (rank : 471)	θ value	6.88961 (rank : 733)
Query Neighborhood Hits	812	Target Neighborhood Hits	518	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

SLY_HUMAN
NC score	0.072078 (rank : 472)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	812	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SFPQ_MOUSE
NC score	0.071985 (rank : 473)	θ value	3.0926 (rank : 643)
Query Neighborhood Hits	812	Target Neighborhood Hits	958	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

STAM1_HUMAN
NC score	0.071916 (rank : 474)	θ value	0.0193708 (rank : 325)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	66
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ACK1_MOUSE
NC score	0.071307 (rank : 475)	θ value	1.38821 (rank : 510)
Query Neighborhood Hits	812	Target Neighborhood Hits	1080	Shared Neighborhood Hits	165
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

LIPB2_HUMAN
NC score	0.071294 (rank : 476)	θ value	0.00390308 (rank : 294)
Query Neighborhood Hits	812	Target Neighborhood Hits	599	Shared Neighborhood Hits	54
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

EP300_HUMAN
NC score	0.071276 (rank : 477)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	812	Target Neighborhood Hits	821	Shared Neighborhood Hits	199
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

M3K11_HUMAN
NC score	0.071184 (rank : 478)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	812	Target Neighborhood Hits	1136	Shared Neighborhood Hits	170
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

WASP_MOUSE
NC score	0.070911 (rank : 479)	θ value	0.813845 (rank : 478)
Query Neighborhood Hits	812	Target Neighborhood Hits	223	Shared Neighborhood Hits	79
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

LCP2_HUMAN
NC score	0.070703 (rank : 480)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	812	Target Neighborhood Hits	531	Shared Neighborhood Hits	123
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ACK1_HUMAN
NC score	0.070226 (rank : 481)	θ value	3.0926 (rank : 601)
Query Neighborhood Hits	812	Target Neighborhood Hits	1140	Shared Neighborhood Hits	172
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

RTP3_MOUSE
NC score	0.070210 (rank : 482)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	812	Target Neighborhood Hits	374	Shared Neighborhood Hits	96
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RIPK2_HUMAN
NC score	0.069876 (rank : 483)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	812	Target Neighborhood Hits	774	Shared Neighborhood Hits	62
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

PCQAP_HUMAN
NC score	0.069758 (rank : 484)	θ value	0.813845 (rank : 473)
Query Neighborhood Hits	812	Target Neighborhood Hits	549	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

ZN207_HUMAN
NC score	0.069414 (rank : 485)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	812	Target Neighborhood Hits	326	Shared Neighborhood Hits	69
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

BAT3_HUMAN
NC score	0.069250 (rank : 486)	θ value	5.27518 (rank : 694)
Query Neighborhood Hits	812	Target Neighborhood Hits	490	Shared Neighborhood Hits	149
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MILK1_MOUSE
NC score	0.068672 (rank : 487)	θ value	5.27518 (rank : 711)
Query Neighborhood Hits	812	Target Neighborhood Hits	788	Shared Neighborhood Hits	193
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PELP1_MOUSE
NC score	0.068401 (rank : 488)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	812	Target Neighborhood Hits	709	Shared Neighborhood Hits	166
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PI5PA_MOUSE
NC score	0.068257 (rank : 489)	θ value	0.0736092 (rank : 357)
Query Neighborhood Hits	812	Target Neighborhood Hits	331	Shared Neighborhood Hits	101
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SF3A2_HUMAN
NC score	0.068211 (rank : 490)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	812	Target Neighborhood Hits	263	Shared Neighborhood Hits	82
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

DGKH_HUMAN
NC score	0.068076 (rank : 491)	θ value	1.81305 (rank : 546)
Query Neighborhood Hits	812	Target Neighborhood Hits	255	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

FMN2_HUMAN
NC score	0.067678 (rank : 492)	θ value	1.81305 (rank : 547)
Query Neighborhood Hits	812	Target Neighborhood Hits	484	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PRPC_HUMAN
NC score	0.067571 (rank : 493)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	812	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

MLKL_HUMAN
NC score	0.067235 (rank : 494)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	812	Target Neighborhood Hits	600	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

WASL_MOUSE
NC score	0.067008 (rank : 495)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	812	Target Neighborhood Hits	339	Shared Neighborhood Hits	109
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MINT_MOUSE
NC score	0.066910 (rank : 496)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	812	Target Neighborhood Hits	1514	Shared Neighborhood Hits	243
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CTDP1_HUMAN
NC score	0.066718 (rank : 497)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	812	Target Neighborhood Hits	416	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

SYNJ1_HUMAN
NC score	0.066681 (rank : 498)	θ value	1.38821 (rank : 534)
Query Neighborhood Hits	812	Target Neighborhood Hits	498	Shared Neighborhood Hits	148
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TNK1_HUMAN
NC score	0.066510 (rank : 499)	θ value	0.00665767 (rank : 303)
Query Neighborhood Hits	812	Target Neighborhood Hits	815	Shared Neighborhood Hits	77
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

SC24C_HUMAN
NC score	0.066395 (rank : 500)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	812	Target Neighborhood Hits	662	Shared Neighborhood Hits	181
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TARA_MOUSE
NC score	0.066385 (rank : 501)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	812	Target Neighborhood Hits	1133	Shared Neighborhood Hits	177
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CNKR2_MOUSE
NC score	0.066374 (rank : 502)	θ value	0.0736092 (rank : 350)
Query Neighborhood Hits	812	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.066336 (rank : 503)	θ value	0.0736092 (rank : 349)
Query Neighborhood Hits	812	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CIZ1_HUMAN
NC score	0.066312 (rank : 504)	θ value	0.47712 (rank : 439)
Query Neighborhood Hits	812	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SFPQ_HUMAN
NC score	0.066292 (rank : 505)	θ value	8.99809 (rank : 803)
Query Neighborhood Hits	812	Target Neighborhood Hits	986	Shared Neighborhood Hits	184
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

BCAR1_MOUSE
NC score	0.065981 (rank : 506)	θ value	5.27518 (rank : 695)
Query Neighborhood Hits	812	Target Neighborhood Hits	438	Shared Neighborhood Hits	137
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BAG3_MOUSE
NC score	0.065691 (rank : 507)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	812	Target Neighborhood Hits	513	Shared Neighborhood Hits	144
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PRR13_HUMAN
NC score	0.065454 (rank : 508)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	812	Target Neighborhood Hits	105	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ZN385_HUMAN
NC score	0.065036 (rank : 509)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	812	Target Neighborhood Hits	614	Shared Neighborhood Hits	147
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

M3K10_HUMAN
NC score	0.064876 (rank : 510)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	812	Target Neighborhood Hits	1071	Shared Neighborhood Hits	124
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

FYN_MOUSE
NC score	0.064807 (rank : 511)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	812	Target Neighborhood Hits	1073	Shared Neighborhood Hits	115
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

FGR_MOUSE
NC score	0.064792 (rank : 512)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	812	Target Neighborhood Hits	1069	Shared Neighborhood Hits	116
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

IWS1_MOUSE
NC score	0.064654 (rank : 513)	θ value	0.125558 (rank : 372)
Query Neighborhood Hits	812	Target Neighborhood Hits	1258	Shared Neighborhood Hits	159
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

YES_HUMAN
NC score	0.064559 (rank : 514)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	812	Target Neighborhood Hits	1059	Shared Neighborhood Hits	115
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

SAPS1_HUMAN
NC score	0.064536 (rank : 515)	θ value	8.99809 (rank : 802)
Query Neighborhood Hits	812	Target Neighborhood Hits	704	Shared Neighborhood Hits	185
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TM108_MOUSE
NC score	0.064442 (rank : 516)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

YES_MOUSE
NC score	0.064379 (rank : 517)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	812	Target Neighborhood Hits	1052	Shared Neighborhood Hits	112
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

FYN_HUMAN
NC score	0.064367 (rank : 518)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	812	Target Neighborhood Hits	1078	Shared Neighborhood Hits	117
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

CITE4_HUMAN
NC score	0.064338 (rank : 519)	θ value	0.365318 (rank : 414)
Query Neighborhood Hits	812	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

FYB_HUMAN
NC score	0.064319 (rank : 520)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	812	Target Neighborhood Hits	379	Shared Neighborhood Hits	110
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

ABL1_MOUSE
NC score	0.064255 (rank : 521)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	812	Target Neighborhood Hits	1178	Shared Neighborhood Hits	158
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

WASL_HUMAN
NC score	0.064212 (rank : 522)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	104
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

FGR_HUMAN
NC score	0.064212 (rank : 523)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	812	Target Neighborhood Hits	1067	Shared Neighborhood Hits	115
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

RIPK2_MOUSE
NC score	0.064126 (rank : 524)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	812	Target Neighborhood Hits	776	Shared Neighborhood Hits	60
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

LARP4_MOUSE
NC score	0.063829 (rank : 525)	θ value	0.125558 (rank : 373)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

SMAP1_MOUSE
NC score	0.063777 (rank : 526)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	812	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CIC_MOUSE
NC score	0.063671 (rank : 527)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	812	Target Neighborhood Hits	742	Shared Neighborhood Hits	192
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

M3KL4_HUMAN
NC score	0.063627 (rank : 528)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	812	Target Neighborhood Hits	1087	Shared Neighborhood Hits	129
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

TIE1_MOUSE
NC score	0.063623 (rank : 529)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	812	Target Neighborhood Hits	1266	Shared Neighborhood Hits	88
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TXK_MOUSE
NC score	0.063620 (rank : 530)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	812	Target Neighborhood Hits	980	Shared Neighborhood Hits	99
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TIE1_HUMAN
NC score	0.063411 (rank : 531)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	812	Target Neighborhood Hits	1241	Shared Neighborhood Hits	86
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MUC5B_HUMAN
NC score	0.063400 (rank : 532)	θ value	0.365318 (rank : 420)
Query Neighborhood Hits	812	Target Neighborhood Hits	1020	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

M3K9_HUMAN
NC score	0.063374 (rank : 533)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	812	Target Neighborhood Hits	1123	Shared Neighborhood Hits	145
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

TXK_HUMAN
NC score	0.063259 (rank : 534)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	812	Target Neighborhood Hits	971	Shared Neighborhood Hits	97
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

ABL1_HUMAN
NC score	0.063167 (rank : 535)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	812	Target Neighborhood Hits	1220	Shared Neighborhood Hits	159
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

AFF1_HUMAN
NC score	0.063105 (rank : 536)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	812	Target Neighborhood Hits	506	Shared Neighborhood Hits	110
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SMR3A_HUMAN
NC score	0.062966 (rank : 537)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	812	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

TIE2_HUMAN
NC score	0.062912 (rank : 538)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	812	Target Neighborhood Hits	1192	Shared Neighborhood Hits	86
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
NC score	0.062856 (rank : 539)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	812	Target Neighborhood Hits	1204	Shared Neighborhood Hits	83
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

PHLB1_HUMAN
NC score	0.062852 (rank : 540)	θ value	0.47712 (rank : 449)
Query Neighborhood Hits	812	Target Neighborhood Hits	1038	Shared Neighborhood Hits	165
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CO5A2_HUMAN
NC score	0.062705 (rank : 541)	θ value	0.00228821 (rank : 282)
Query Neighborhood Hits	812	Target Neighborhood Hits	760	Shared Neighborhood Hits	182
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

SRC_HUMAN
NC score	0.062688 (rank : 542)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	812	Target Neighborhood Hits	1058	Shared Neighborhood Hits	116
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

FRK_HUMAN
NC score	0.062455 (rank : 543)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	812	Target Neighborhood Hits	1058	Shared Neighborhood Hits	109
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

BTK_HUMAN
NC score	0.062361 (rank : 544)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	812	Target Neighborhood Hits	1026	Shared Neighborhood Hits	111
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

PO121_MOUSE
NC score	0.062301 (rank : 545)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	812	Target Neighborhood Hits	345	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

HCK_MOUSE
NC score	0.062090 (rank : 546)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	812	Target Neighborhood Hits	1029	Shared Neighborhood Hits	111
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

CDN1C_HUMAN
NC score	0.062029 (rank : 547)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	59
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

TB182_HUMAN
NC score	0.061971 (rank : 548)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	812	Target Neighborhood Hits	414	Shared Neighborhood Hits	105
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

BTK_MOUSE
NC score	0.061842 (rank : 549)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	812	Target Neighborhood Hits	1017	Shared Neighborhood Hits	108
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

TEC_HUMAN
NC score	0.061835 (rank : 550)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	812	Target Neighborhood Hits	1006	Shared Neighborhood Hits	103
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

K1543_HUMAN
NC score	0.061779 (rank : 551)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	812	Target Neighborhood Hits	435	Shared Neighborhood Hits	112
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

HCK_HUMAN
NC score	0.061773 (rank : 552)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	812	Target Neighborhood Hits	1035	Shared Neighborhood Hits	112
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

WNK2_HUMAN
NC score	0.061760 (rank : 553)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	812	Target Neighborhood Hits	1407	Shared Neighborhood Hits	230
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

TNK1_MOUSE
NC score	0.061673 (rank : 554)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	812	Target Neighborhood Hits	806	Shared Neighborhood Hits	69
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

ERBB4_HUMAN
NC score	0.061528 (rank : 555)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	812	Target Neighborhood Hits	910	Shared Neighborhood Hits	71
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

SRC_MOUSE
NC score	0.061524 (rank : 556)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	812	Target Neighborhood Hits	1033	Shared Neighborhood Hits	112
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

ERBB2_HUMAN
NC score	0.061317 (rank : 557)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	812	Target Neighborhood Hits	1073	Shared Neighborhood Hits	110
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

IRAK3_HUMAN
NC score	0.061311 (rank : 558)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	812	Target Neighborhood Hits	644	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

T22D2_HUMAN
NC score	0.061304 (rank : 559)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	812	Target Neighborhood Hits	250	Shared Neighborhood Hits	84
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

AATK_HUMAN
NC score	0.061296 (rank : 560)	θ value	1.38821 (rank : 509)
Query Neighborhood Hits	812	Target Neighborhood Hits	1243	Shared Neighborhood Hits	193
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

K0310_HUMAN
NC score	0.061152 (rank : 561)	θ value	6.88961 (rank : 746)
Query Neighborhood Hits	812	Target Neighborhood Hits	420	Shared Neighborhood Hits	126
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

ITK_HUMAN
NC score	0.061034 (rank : 562)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	812	Target Neighborhood Hits	1016	Shared Neighborhood Hits	103
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

CO1A1_MOUSE
NC score	0.060976 (rank : 563)	θ value	0.813845 (rank : 471)
Query Neighborhood Hits	812	Target Neighborhood Hits	457	Shared Neighborhood Hits	132
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

IRAK3_MOUSE
NC score	0.060939 (rank : 564)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	812	Target Neighborhood Hits	628	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

LCK_MOUSE
NC score	0.060936 (rank : 565)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	812	Target Neighborhood Hits	981	Shared Neighborhood Hits	95
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

TROAP_HUMAN
NC score	0.060901 (rank : 566)	θ value	4.03905 (rank : 687)
Query Neighborhood Hits	812	Target Neighborhood Hits	258	Shared Neighborhood Hits	71
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TEC_MOUSE
NC score	0.060887 (rank : 567)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	812	Target Neighborhood Hits	1006	Shared Neighborhood Hits	104
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ZAP70_HUMAN
NC score	0.060884 (rank : 568)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	812	Target Neighborhood Hits	893	Shared Neighborhood Hits	75
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

FER_HUMAN
NC score	0.060850 (rank : 569)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	812	Target Neighborhood Hits	1278	Shared Neighborhood Hits	96
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

SSBP4_HUMAN
NC score	0.060796 (rank : 570)	θ value	0.365318 (rank : 426)
Query Neighborhood Hits	812	Target Neighborhood Hits	753	Shared Neighborhood Hits	192
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

NCOR2_HUMAN
NC score	0.060759 (rank : 571)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	812	Target Neighborhood Hits	870	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MAP4_MOUSE
NC score	0.060619 (rank : 572)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	812	Target Neighborhood Hits	409	Shared Neighborhood Hits	93
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

LCK_HUMAN
NC score	0.060536 (rank : 573)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	812	Target Neighborhood Hits	987	Shared Neighborhood Hits	96
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

SMAP1_HUMAN
NC score	0.060532 (rank : 574)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	812	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

FAK2_HUMAN
NC score	0.060429 (rank : 575)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	812	Target Neighborhood Hits	847	Shared Neighborhood Hits	66
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

PRR8_HUMAN
NC score	0.060371 (rank : 576)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	812	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

K1802_HUMAN
NC score	0.060345 (rank : 577)	θ value	5.27518 (rank : 705)
Query Neighborhood Hits	812	Target Neighborhood Hits	1378	Shared Neighborhood Hits	202
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ERBB2_MOUSE
NC score	0.060289 (rank : 578)	θ value	5.27518 (rank : 701)
Query Neighborhood Hits	812	Target Neighborhood Hits	918	Shared Neighborhood Hits	72
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ITK_MOUSE
NC score	0.060254 (rank : 579)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	812	Target Neighborhood Hits	985	Shared Neighborhood Hits	94
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

MLKL_MOUSE
NC score	0.060238 (rank : 580)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	812	Target Neighborhood Hits	707	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

GUC2G_MOUSE
NC score	0.060170 (rank : 581)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	812	Target Neighborhood Hits	644	Shared Neighborhood Hits	59
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

DMRTD_HUMAN
NC score	0.060077 (rank : 582)	θ value	0.47712 (rank : 445)
Query Neighborhood Hits	812	Target Neighborhood Hits	216	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

FAK2_MOUSE
NC score	0.060066 (rank : 583)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	812	Target Neighborhood Hits	851	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

SH3K1_HUMAN
NC score	0.059992 (rank : 584)	θ value	8.99809 (rank : 804)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	82
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

BLK_HUMAN
NC score	0.059914 (rank : 585)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	812	Target Neighborhood Hits	994	Shared Neighborhood Hits	103
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

FAK1_HUMAN
NC score	0.059905 (rank : 586)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	812	Target Neighborhood Hits	850	Shared Neighborhood Hits	66
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

LYN_MOUSE
NC score	0.059898 (rank : 587)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	812	Target Neighborhood Hits	1023	Shared Neighborhood Hits	108
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

ZAP70_MOUSE
NC score	0.059877 (rank : 588)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	812	Target Neighborhood Hits	905	Shared Neighborhood Hits	74
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

CO3A1_MOUSE
NC score	0.059743 (rank : 589)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	812	Target Neighborhood Hits	466	Shared Neighborhood Hits	134
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CRTC1_HUMAN
NC score	0.059735 (rank : 590)	θ value	8.99809 (rank : 778)
Query Neighborhood Hits	812	Target Neighborhood Hits	319	Shared Neighborhood Hits	114
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

LYN_HUMAN
NC score	0.059720 (rank : 591)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	812	Target Neighborhood Hits	1022	Shared Neighborhood Hits	105
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

PTK6_MOUSE
NC score	0.059697 (rank : 592)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	812	Target Neighborhood Hits	1026	Shared Neighborhood Hits	103
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK6_HUMAN
NC score	0.059674 (rank : 593)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	812	Target Neighborhood Hits	1020	Shared Neighborhood Hits	103
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

FAK1_MOUSE
NC score	0.059671 (rank : 594)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	812	Target Neighborhood Hits	850	Shared Neighborhood Hits	65
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

CO4A5_HUMAN
NC score	0.059667 (rank : 595)	θ value	0.279714 (rank : 402)
Query Neighborhood Hits	812	Target Neighborhood Hits	383	Shared Neighborhood Hits	110
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

LIPB1_HUMAN
NC score	0.059647 (rank : 596)	θ value	0.21417 (rank : 393)
Query Neighborhood Hits	812	Target Neighborhood Hits	640	Shared Neighborhood Hits	65
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

STAM2_MOUSE
NC score	0.059646 (rank : 597)	θ value	0.62314 (rank : 466)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	61
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ROR2_MOUSE
NC score	0.059631 (rank : 598)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	812	Target Neighborhood Hits	1000	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

VASP_MOUSE
NC score	0.059541 (rank : 599)	θ value	0.0736092 (rank : 362)
Query Neighborhood Hits	812	Target Neighborhood Hits	195	Shared Neighborhood Hits	70
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

MBB1A_HUMAN
NC score	0.059539 (rank : 600)	θ value	1.38821 (rank : 525)
Query Neighborhood Hits	812	Target Neighborhood Hits	665	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MILK1_HUMAN
NC score	0.059528 (rank : 601)	θ value	0.365318 (rank : 419)
Query Neighborhood Hits	812	Target Neighborhood Hits	427	Shared Neighborhood Hits	117
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PO121_HUMAN
NC score	0.059493 (rank : 602)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	812	Target Neighborhood Hits	344	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CO3A1_HUMAN
NC score	0.059456 (rank : 603)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	812	Target Neighborhood Hits	452	Shared Neighborhood Hits	126
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

HRX_HUMAN
NC score	0.059441 (rank : 604)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	812	Target Neighborhood Hits	825	Shared Neighborhood Hits	142
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

3BP1_HUMAN
NC score	0.059269 (rank : 605)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	812	Target Neighborhood Hits	376	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

DDR1_HUMAN
NC score	0.059253 (rank : 606)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	812	Target Neighborhood Hits	819	Shared Neighborhood Hits	64
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
NC score	0.059223 (rank : 607)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	812	Target Neighborhood Hits	818	Shared Neighborhood Hits	64
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

IRAK1_HUMAN
NC score	0.059201 (rank : 608)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	812	Target Neighborhood Hits	820	Shared Neighborhood Hits	83
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

CO1A1_HUMAN
NC score	0.059200 (rank : 609)	θ value	1.81305 (rank : 544)
Query Neighborhood Hits	812	Target Neighborhood Hits	475	Shared Neighborhood Hits	133
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SH3K1_MOUSE
NC score	0.059117 (rank : 610)	θ value	8.99809 (rank : 805)
Query Neighborhood Hits	812	Target Neighborhood Hits	332	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TCGAP_MOUSE
NC score	0.059037 (rank : 611)	θ value	4.03905 (rank : 686)
Query Neighborhood Hits	812	Target Neighborhood Hits	409	Shared Neighborhood Hits	126
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GRAP_HUMAN
NC score	0.059022 (rank : 612)	θ value	0.00134147 (rank : 277)
Query Neighborhood Hits	812	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SYNJ1_MOUSE
NC score	0.058961 (rank : 613)	θ value	6.88961 (rank : 761)
Query Neighborhood Hits	812	Target Neighborhood Hits	516	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BLK_MOUSE
NC score	0.058920 (rank : 614)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	812	Target Neighborhood Hits	992	Shared Neighborhood Hits	98
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

EGFR_HUMAN
NC score	0.058894 (rank : 615)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	812	Target Neighborhood Hits	939	Shared Neighborhood Hits	67
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

LTK_HUMAN
NC score	0.058843 (rank : 616)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	812	Target Neighborhood Hits	774	Shared Neighborhood Hits	63
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

CS007_HUMAN
NC score	0.058752 (rank : 617)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	812	Target Neighborhood Hits	401	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

INSR_HUMAN
NC score	0.058744 (rank : 618)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	812	Target Neighborhood Hits	963	Shared Neighborhood Hits	70
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

EGFR_MOUSE
NC score	0.058734 (rank : 619)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	812	Target Neighborhood Hits	927	Shared Neighborhood Hits	69
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

AATK_MOUSE
NC score	0.058730 (rank : 620)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	812	Target Neighborhood Hits	942	Shared Neighborhood Hits	116
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

RIPK3_HUMAN
NC score	0.058690 (rank : 621)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	812	Target Neighborhood Hits	828	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

ROR1_HUMAN
NC score	0.058662 (rank : 622)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	812	Target Neighborhood Hits	1018	Shared Neighborhood Hits	68
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

DGKK_HUMAN
NC score	0.058639 (rank : 623)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	812	Target Neighborhood Hits	378	Shared Neighborhood Hits	105
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

SFR15_HUMAN
NC score	0.058567 (rank : 624)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	812	Target Neighborhood Hits	368	Shared Neighborhood Hits	92
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

ABL2_HUMAN
NC score	0.058543 (rank : 625)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	812	Target Neighborhood Hits	1045	Shared Neighborhood Hits	107
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

CT032_HUMAN
NC score	0.058540 (rank : 626)	θ value	6.88961 (rank : 738)
Query Neighborhood Hits	812	Target Neighborhood Hits	235	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ROR1_MOUSE
NC score	0.058520 (rank : 627)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	812	Target Neighborhood Hits	1025	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
NC score	0.058508 (rank : 628)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	812	Target Neighborhood Hits	1014	Shared Neighborhood Hits	68
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

SMP1L_HUMAN
NC score	0.058473 (rank : 629)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	812	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

MATK_HUMAN
NC score	0.058367 (rank : 630)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	812	Target Neighborhood Hits	954	Shared Neighborhood Hits	85
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

RYK_HUMAN
NC score	0.058365 (rank : 631)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	812	Target Neighborhood Hits	701	Shared Neighborhood Hits	58
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

INSRR_MOUSE
NC score	0.058350 (rank : 632)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	812	Target Neighborhood Hits	961	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IRAK2_HUMAN
NC score	0.058301 (rank : 633)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	812	Target Neighborhood Hits	714	Shared Neighborhood Hits	64
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

KSYK_MOUSE
NC score	0.058261 (rank : 634)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	812	Target Neighborhood Hits	944	Shared Neighborhood Hits	87
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

CCNK_MOUSE
NC score	0.058202 (rank : 635)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	95
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

MATK_MOUSE
NC score	0.058168 (rank : 636)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	812	Target Neighborhood Hits	952	Shared Neighborhood Hits	86
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

INSRR_HUMAN
NC score	0.058157 (rank : 637)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	812	Target Neighborhood Hits	950	Shared Neighborhood Hits	79
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LTK_MOUSE
NC score	0.058081 (rank : 638)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	812	Target Neighborhood Hits	770	Shared Neighborhood Hits	64
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

MET_HUMAN
NC score	0.058066 (rank : 639)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	812	Target Neighborhood Hits	831	Shared Neighborhood Hits	62
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

TRPC1_HUMAN
NC score	0.058014 (rank : 640)	θ value	3.0926 (rank : 645)
Query Neighborhood Hits	812	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

RIPK3_MOUSE
NC score	0.057983 (rank : 641)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	812	Target Neighborhood Hits	867	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

MET_MOUSE
NC score	0.057959 (rank : 642)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	812	Target Neighborhood Hits	844	Shared Neighborhood Hits	64
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

WASF2_MOUSE
NC score	0.057949 (rank : 643)	θ value	6.88961 (rank : 765)
Query Neighborhood Hits	812	Target Neighborhood Hits	315	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

INSR_MOUSE
NC score	0.057909 (rank : 644)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	812	Target Neighborhood Hits	968	Shared Neighborhood Hits	68
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TM108_HUMAN
NC score	0.057895 (rank : 645)	θ value	8.99809 (rank : 809)
Query Neighborhood Hits	812	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CSK_HUMAN
NC score	0.057823 (rank : 646)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CEL_HUMAN
NC score	0.057823 (rank : 647)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	812	Target Neighborhood Hits	896	Shared Neighborhood Hits	199
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

RYK_MOUSE
NC score	0.057736 (rank : 648)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	812	Target Neighborhood Hits	715	Shared Neighborhood Hits	58
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

COIA1_HUMAN
NC score	0.057638 (rank : 649)	θ value	0.62314 (rank : 456)
Query Neighborhood Hits	812	Target Neighborhood Hits	447	Shared Neighborhood Hits	125
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

RIMB1_HUMAN
NC score	0.057629 (rank : 650)	θ value	0.62314 (rank : 463)
Query Neighborhood Hits	812	Target Neighborhood Hits	1479	Shared Neighborhood Hits	189
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

KSYK_HUMAN
NC score	0.057609 (rank : 651)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	812	Target Neighborhood Hits	901	Shared Neighborhood Hits	73
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

STAM2_HUMAN
NC score	0.057505 (rank : 652)	θ value	0.47712 (rank : 451)
Query Neighborhood Hits	812	Target Neighborhood Hits	288	Shared Neighborhood Hits	66
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

CEND2_HUMAN
NC score	0.057411 (rank : 653)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	812	Target Neighborhood Hits	166	Shared Neighborhood Hits	36
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

DDR2_HUMAN
NC score	0.057321 (rank : 654)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	812	Target Neighborhood Hits	818	Shared Neighborhood Hits	62
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

SMP1L_MOUSE
NC score	0.057216 (rank : 655)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	812	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

ROS_HUMAN
NC score	0.057158 (rank : 656)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	812	Target Neighborhood Hits	907	Shared Neighborhood Hits	64
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

MERTK_MOUSE
NC score	0.057118 (rank : 657)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	812	Target Neighborhood Hits	974	Shared Neighborhood Hits	69
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

UFO_MOUSE
NC score	0.057044 (rank : 658)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	812	Target Neighborhood Hits	988	Shared Neighborhood Hits	70
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

UFO_HUMAN
NC score	0.057018 (rank : 659)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	812	Target Neighborhood Hits	981	Shared Neighborhood Hits	77
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

ALK_MOUSE
NC score	0.056987 (rank : 660)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	812	Target Neighborhood Hits	811	Shared Neighborhood Hits	69
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

MERTK_HUMAN
NC score	0.056979 (rank : 661)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	812	Target Neighborhood Hits	988	Shared Neighborhood Hits	70
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

CENA1_HUMAN
NC score	0.056953 (rank : 662)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	812	Target Neighborhood Hits	87	Shared Neighborhood Hits	26
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SRMS_MOUSE
NC score	0.056948 (rank : 663)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	812	Target Neighborhood Hits	964	Shared Neighborhood Hits	85
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

M3K7_MOUSE
NC score	0.056714 (rank : 664)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	812	Target Neighborhood Hits	892	Shared Neighborhood Hits	63
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

CSK_MOUSE
NC score	0.056706 (rank : 665)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	812	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

SRMS_HUMAN
NC score	0.056669 (rank : 666)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	812	Target Neighborhood Hits	946	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

M3K7_HUMAN
NC score	0.056644 (rank : 667)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	812	Target Neighborhood Hits	892	Shared Neighborhood Hits	62
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

IGF1R_MOUSE
NC score	0.056616 (rank : 668)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	812	Target Neighborhood Hits	973	Shared Neighborhood Hits	72
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

TYRO3_MOUSE
NC score	0.056569 (rank : 669)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	812	Target Neighborhood Hits	1007	Shared Neighborhood Hits	66
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

GUC2C_HUMAN
NC score	0.056559 (rank : 670)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	812	Target Neighborhood Hits	624	Shared Neighborhood Hits	58
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

FES_MOUSE
NC score	0.056546 (rank : 671)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	812	Target Neighborhood Hits	980	Shared Neighborhood Hits	79
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

MEGF9_MOUSE
NC score	0.056523 (rank : 672)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	812	Target Neighborhood Hits	896	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DDR2_MOUSE
NC score	0.056521 (rank : 673)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	812	Target Neighborhood Hits	813	Shared Neighborhood Hits	62
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

SGIP1_MOUSE
NC score	0.056456 (rank : 674)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	812	Target Neighborhood Hits	180	Shared Neighborhood Hits	72
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MAP4_HUMAN
NC score	0.056432 (rank : 675)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	812	Target Neighborhood Hits	428	Shared Neighborhood Hits	93
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TYRO3_HUMAN
NC score	0.056425 (rank : 676)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	812	Target Neighborhood Hits	995	Shared Neighborhood Hits	67
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

RON_MOUSE
NC score	0.056358 (rank : 677)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	812	Target Neighborhood Hits	836	Shared Neighborhood Hits	62
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ATX2L_HUMAN
NC score	0.056354 (rank : 678)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	812	Target Neighborhood Hits	443	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BMX_MOUSE
NC score	0.056354 (rank : 679)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	812	Target Neighborhood Hits	912	Shared Neighborhood Hits	75
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

IGF1R_HUMAN
NC score	0.056344 (rank : 680)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	812	Target Neighborhood Hits	977	Shared Neighborhood Hits	70
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

NTRK1_HUMAN
NC score	0.056308 (rank : 681)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	812	Target Neighborhood Hits	1023	Shared Neighborhood Hits	64
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

ALK_HUMAN
NC score	0.056193 (rank : 682)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	812	Target Neighborhood Hits	795	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PRR13_MOUSE
NC score	0.056105 (rank : 683)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	812	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RON_HUMAN
NC score	0.056004 (rank : 684)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	812	Target Neighborhood Hits	842	Shared Neighborhood Hits	65
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

BMX_HUMAN
NC score	0.055998 (rank : 685)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	812	Target Neighborhood Hits	942	Shared Neighborhood Hits	78
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

RPB1_HUMAN
NC score	0.055946 (rank : 686)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	812	Target Neighborhood Hits	362	Shared Neighborhood Hits	95
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.055914 (rank : 687)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	812	Target Neighborhood Hits	363	Shared Neighborhood Hits	95
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

MAST4_HUMAN
NC score	0.055878 (rank : 688)	θ value	1.09739e-05 (rank : 209)
Query Neighborhood Hits	812	Target Neighborhood Hits	1804	Shared Neighborhood Hits	262
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

FES_HUMAN
NC score	0.055748 (rank : 689)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	812	Target Neighborhood Hits	978	Shared Neighborhood Hits	76
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

IWS1_HUMAN
NC score	0.055711 (rank : 690)	θ value	1.81305 (rank : 551)
Query Neighborhood Hits	812	Target Neighborhood Hits	1241	Shared Neighborhood Hits	139
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PDCD7_HUMAN
NC score	0.055707 (rank : 691)	θ value	0.125558 (rank : 375)
Query Neighborhood Hits	812	Target Neighborhood Hits	255	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PELP1_HUMAN
NC score	0.055616 (rank : 692)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	812	Target Neighborhood Hits	596	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CNOT3_MOUSE
NC score	0.055438 (rank : 693)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	812	Target Neighborhood Hits	504	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RET_MOUSE
NC score	0.055383 (rank : 694)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	812	Target Neighborhood Hits	884	Shared Neighborhood Hits	63
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

MLTK_HUMAN
NC score	0.055330 (rank : 695)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	812	Target Neighborhood Hits	911	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

CNOT3_HUMAN
NC score	0.055276 (rank : 696)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	812	Target Neighborhood Hits	425	Shared Neighborhood Hits	97
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RET_HUMAN
NC score	0.055246 (rank : 697)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	812	Target Neighborhood Hits	873	Shared Neighborhood Hits	63
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

M3K12_HUMAN
NC score	0.055188 (rank : 698)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	812	Target Neighborhood Hits	940	Shared Neighborhood Hits	100
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

COHA1_HUMAN
NC score	0.055128 (rank : 699)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	812	Target Neighborhood Hits	400	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

LIPB1_MOUSE
NC score	0.055116 (rank : 700)	θ value	0.365318 (rank : 418)
Query Neighborhood Hits	812	Target Neighborhood Hits	727	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MLTK_MOUSE
NC score	0.055037 (rank : 701)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

CD2AP_MOUSE
NC score	0.055035 (rank : 702)	θ value	8.99809 (rank : 770)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

ERBB3_HUMAN
NC score	0.055027 (rank : 703)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	812	Target Neighborhood Hits	918	Shared Neighborhood Hits	70
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

HRBL_MOUSE
NC score	0.055020 (rank : 704)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	812	Target Neighborhood Hits	269	Shared Neighborhood Hits	84
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MINT_HUMAN
NC score	0.054960 (rank : 705)	θ value	8.99809 (rank : 794)
Query Neighborhood Hits	812	Target Neighborhood Hits	1291	Shared Neighborhood Hits	177
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

M3K12_MOUSE
NC score	0.054946 (rank : 706)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	812	Target Neighborhood Hits	957	Shared Neighborhood Hits	98
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

ATX2_MOUSE
NC score	0.054906 (rank : 707)	θ value	3.0926 (rank : 605)
Query Neighborhood Hits	812	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

RAF1_HUMAN
NC score	0.054893 (rank : 708)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	812	Target Neighborhood Hits	886	Shared Neighborhood Hits	70
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

PSL1_HUMAN
NC score	0.054794 (rank : 709)	θ value	3.0926 (rank : 638)
Query Neighborhood Hits	812	Target Neighborhood Hits	650	Shared Neighborhood Hits	152
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RAF1_MOUSE
NC score	0.054691 (rank : 710)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	812	Target Neighborhood Hits	886	Shared Neighborhood Hits	72
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ABI2_HUMAN
NC score	0.054687 (rank : 711)	θ value	5.27518 (rank : 691)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ITSN1_MOUSE
NC score	0.054649 (rank : 712)	θ value	0.00134147 (rank : 278)
Query Neighborhood Hits	812	Target Neighborhood Hits	1669	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ARI1B_HUMAN
NC score	0.054637 (rank : 713)	θ value	3.0926 (rank : 602)
Query Neighborhood Hits	812	Target Neighborhood Hits	567	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

JPH2_HUMAN
NC score	0.054600 (rank : 714)	θ value	0.365318 (rank : 417)
Query Neighborhood Hits	812	Target Neighborhood Hits	639	Shared Neighborhood Hits	177
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BRAF1_HUMAN
NC score	0.054498 (rank : 715)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	812	Target Neighborhood Hits	883	Shared Neighborhood Hits	71
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

K1683_HUMAN
NC score	0.054483 (rank : 716)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	812	Target Neighborhood Hits	240	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

LAD1_HUMAN
NC score	0.054457 (rank : 717)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	812	Target Neighborhood Hits	441	Shared Neighborhood Hits	77
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

TCRG1_MOUSE
NC score	0.054451 (rank : 718)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	812	Target Neighborhood Hits	947	Shared Neighborhood Hits	126
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

DOT1L_HUMAN
NC score	0.054446 (rank : 719)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	812	Target Neighborhood Hits	660	Shared Neighborhood Hits	141
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ERBB3_MOUSE
NC score	0.054361 (rank : 720)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	812	Target Neighborhood Hits	898	Shared Neighborhood Hits	70
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

TCRG1_HUMAN
NC score	0.054344 (rank : 721)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	812	Target Neighborhood Hits	929	Shared Neighborhood Hits	122
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TRPC1_MOUSE
NC score	0.054193 (rank : 722)	θ value	1.38821 (rank : 535)
Query Neighborhood Hits	812	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

IRAK1_MOUSE
NC score	0.054180 (rank : 723)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	812	Target Neighborhood Hits	784	Shared Neighborhood Hits	70
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

PKHA6_MOUSE
NC score	0.054178 (rank : 724)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	812	Target Neighborhood Hits	591	Shared Neighborhood Hits	126
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GUC2F_HUMAN
NC score	0.054046 (rank : 725)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	812	Target Neighborhood Hits	740	Shared Neighborhood Hits	58
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

FA47A_HUMAN
NC score	0.054035 (rank : 726)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	812	Target Neighborhood Hits	451	Shared Neighborhood Hits	104
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

VASP_HUMAN
NC score	0.053990 (rank : 727)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	74
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ARFG1_MOUSE
NC score	0.053937 (rank : 728)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	812	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

GRAP_MOUSE
NC score	0.053927 (rank : 729)	θ value	0.0736092 (rank : 352)
Query Neighborhood Hits	812	Target Neighborhood Hits	309	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

COHA1_MOUSE
NC score	0.053908 (rank : 730)	θ value	1.06291 (rank : 487)
Query Neighborhood Hits	812	Target Neighborhood Hits	414	Shared Neighborhood Hits	119
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MTSS1_MOUSE
NC score	0.053903 (rank : 731)	θ value	6.88961 (rank : 748)
Query Neighborhood Hits	812	Target Neighborhood Hits	592	Shared Neighborhood Hits	154
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

KI67_HUMAN
NC score	0.053765 (rank : 732)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	812	Target Neighborhood Hits	581	Shared Neighborhood Hits	93
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MADCA_HUMAN
NC score	0.053679 (rank : 733)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	812	Target Neighborhood Hits	221	Shared Neighborhood Hits	72
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

ARFG3_MOUSE
NC score	0.053644 (rank : 734)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	812	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

FA47B_HUMAN
NC score	0.053613 (rank : 735)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	812	Target Neighborhood Hits	431	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TRDN_HUMAN
NC score	0.053495 (rank : 736)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	812	Target Neighborhood Hits	542	Shared Neighborhood Hits	50
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

NTRK3_HUMAN
NC score	0.053493 (rank : 737)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	812	Target Neighborhood Hits	1115	Shared Neighborhood Hits	68
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

SELV_HUMAN
NC score	0.053482 (rank : 738)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	812	Target Neighborhood Hits	118	Shared Neighborhood Hits	43
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

ARFG3_HUMAN
NC score	0.053478 (rank : 739)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	812	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CD2AP_HUMAN
NC score	0.053461 (rank : 740)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	812	Target Neighborhood Hits	315	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2_HUMAN
NC score	0.053420 (rank : 741)	θ value	1.38821 (rank : 512)
Query Neighborhood Hits	812	Target Neighborhood Hits	504	Shared Neighborhood Hits	118
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

ARFG1_HUMAN
NC score	0.053318 (rank : 742)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	812	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARAF_HUMAN
NC score	0.053268 (rank : 743)	θ value	8.99809 (rank : 767)
Query Neighborhood Hits	812	Target Neighborhood Hits	924	Shared Neighborhood Hits	82
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ANPRB_MOUSE
NC score	0.053265 (rank : 744)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	812	Target Neighborhood Hits	607	Shared Neighborhood Hits	54
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

NTRK2_HUMAN
NC score	0.053165 (rank : 745)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	812	Target Neighborhood Hits	1081	Shared Neighborhood Hits	65
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

TMAP1_HUMAN
NC score	0.053141 (rank : 746)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	812	Target Neighborhood Hits	140	Shared Neighborhood Hits	57
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

EFS_MOUSE
NC score	0.053097 (rank : 747)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	812	Target Neighborhood Hits	389	Shared Neighborhood Hits	111
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

NTRK2_MOUSE
NC score	0.053071 (rank : 748)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	812	Target Neighborhood Hits	1088	Shared Neighborhood Hits	66
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

CENA2_MOUSE
NC score	0.052907 (rank : 749)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	812	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

TULP4_HUMAN
NC score	0.052746 (rank : 750)	θ value	2.36792 (rank : 596)
Query Neighborhood Hits	812	Target Neighborhood Hits	426	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SSB4_HUMAN
NC score	0.052660 (rank : 751)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	812	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

DIAP1_MOUSE
NC score	0.052605 (rank : 752)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	812	Target Neighborhood Hits	839	Shared Neighborhood Hits	123
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

CRK_HUMAN
NC score	0.052354 (rank : 753)	θ value	0.0252991 (rank : 328)
Query Neighborhood Hits	812	Target Neighborhood Hits	308	Shared Neighborhood Hits	60
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

ARAF_MOUSE
NC score	0.052331 (rank : 754)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	69
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

MOS_HUMAN
NC score	0.052301 (rank : 755)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	812	Target Neighborhood Hits	829	Shared Neighborhood Hits	62
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

RIPK1_HUMAN
NC score	0.052216 (rank : 756)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	812	Target Neighborhood Hits	891	Shared Neighborhood Hits	71
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

MUSK_HUMAN
NC score	0.052100 (rank : 757)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	812	Target Neighborhood Hits	1074	Shared Neighborhood Hits	65
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

ANPRB_HUMAN
NC score	0.052089 (rank : 758)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	812	Target Neighborhood Hits	646	Shared Neighborhood Hits	56
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

CENA2_HUMAN
NC score	0.052042 (rank : 759)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	812	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

SREC2_HUMAN
NC score	0.051829 (rank : 760)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	812	Target Neighborhood Hits	645	Shared Neighborhood Hits	103
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

GUC2E_MOUSE
NC score	0.051692 (rank : 761)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	812	Target Neighborhood Hits	692	Shared Neighborhood Hits	58
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

CO039_MOUSE
NC score	0.051688 (rank : 762)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	812	Target Neighborhood Hits	445	Shared Neighborhood Hits	122
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

WASP_HUMAN
NC score	0.051610 (rank : 763)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	812	Target Neighborhood Hits	195	Shared Neighborhood Hits	81
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

BRD4_MOUSE
NC score	0.051513 (rank : 764)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	812	Target Neighborhood Hits	845	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MUSK_MOUSE
NC score	0.051501 (rank : 765)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	812	Target Neighborhood Hits	1057	Shared Neighborhood Hits	64
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

SGIP1_HUMAN
NC score	0.051491 (rank : 766)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

M3K13_HUMAN
NC score	0.051468 (rank : 767)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	812	Target Neighborhood Hits	911	Shared Neighborhood Hits	73
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

SELPL_MOUSE
NC score	0.051460 (rank : 768)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	812	Target Neighborhood Hits	588	Shared Neighborhood Hits	124
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

EFS_HUMAN
NC score	0.051438 (rank : 769)	θ value	5.27518 (rank : 699)
Query Neighborhood Hits	812	Target Neighborhood Hits	348	Shared Neighborhood Hits	102
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

MAP1A_HUMAN
NC score	0.051403 (rank : 770)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	812	Target Neighborhood Hits	1626	Shared Neighborhood Hits	204
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

BTBDC_HUMAN
NC score	0.051243 (rank : 771)	θ value	0.279714 (rank : 400)
Query Neighborhood Hits	812	Target Neighborhood Hits	248	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

KIT_HUMAN
NC score	0.051214 (rank : 772)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	812	Target Neighborhood Hits	953	Shared Neighborhood Hits	66
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

WNK4_HUMAN
NC score	0.051211 (rank : 773)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	812	Target Neighborhood Hits	1043	Shared Neighborhood Hits	156
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TESK2_HUMAN
NC score	0.051095 (rank : 774)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	812	Target Neighborhood Hits	851	Shared Neighborhood Hits	67
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

ANPRA_MOUSE
NC score	0.051077 (rank : 775)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	812	Target Neighborhood Hits	600	Shared Neighborhood Hits	57
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

PCQAP_MOUSE
NC score	0.051040 (rank : 776)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	812	Target Neighborhood Hits	506	Shared Neighborhood Hits	109
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

WASF1_MOUSE
NC score	0.051033 (rank : 777)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

AN13D_MOUSE
NC score	0.051015 (rank : 778)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	812	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

NCOR2_MOUSE
NC score	0.050939 (rank : 779)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	812	Target Neighborhood Hits	790	Shared Neighborhood Hits	135
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PHC2_HUMAN
NC score	0.050936 (rank : 780)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	812	Target Neighborhood Hits	388	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

AFF1_MOUSE
NC score	0.050815 (rank : 781)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	812	Target Neighborhood Hits	351	Shared Neighborhood Hits	90
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

SPT5H_MOUSE
NC score	0.050799 (rank : 782)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	812	Target Neighborhood Hits	437	Shared Neighborhood Hits	129
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

JAK1_HUMAN
NC score	0.050779 (rank : 783)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	812	Target Neighborhood Hits	858	Shared Neighborhood Hits	62
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

AN13D_HUMAN
NC score	0.050651 (rank : 784)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	812	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

JAK1_MOUSE
NC score	0.050649 (rank : 785)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	812	Target Neighborhood Hits	854	Shared Neighborhood Hits	62
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

ELN_HUMAN
NC score	0.050617 (rank : 786)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	812	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

WASF1_HUMAN
NC score	0.050595 (rank : 787)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	88
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

KIT_MOUSE
NC score	0.050522 (rank : 788)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	812	Target Neighborhood Hits	949	Shared Neighborhood Hits	64
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

RIPK1_MOUSE
NC score	0.050418 (rank : 789)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	68
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

VCX3_HUMAN
NC score	0.050391 (rank : 790)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	812	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

SPT5H_HUMAN
NC score	0.050388 (rank : 791)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	812	Target Neighborhood Hits	436	Shared Neighborhood Hits	128
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

ENL_HUMAN
NC score	0.050006 (rank : 792)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	64
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

PKHA6_HUMAN
NC score	0.049835 (rank : 793)	θ value	0.21417 (rank : 395)
Query Neighborhood Hits	812	Target Neighborhood Hits	556	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CRKL_HUMAN
NC score	0.049470 (rank : 794)	θ value	2.36792 (rank : 575)
Query Neighborhood Hits	812	Target Neighborhood Hits	313	Shared Neighborhood Hits	65
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CO7A1_HUMAN
NC score	0.049456 (rank : 795)	θ value	0.365318 (rank : 415)
Query Neighborhood Hits	812	Target Neighborhood Hits	807	Shared Neighborhood Hits	173
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CRK_MOUSE
NC score	0.049362 (rank : 796)	θ value	0.0736092 (rank : 351)
Query Neighborhood Hits	812	Target Neighborhood Hits	314	Shared Neighborhood Hits	61
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

ITSN1_HUMAN
NC score	0.049261 (rank : 797)	θ value	0.279714 (rank : 404)
Query Neighborhood Hits	812	Target Neighborhood Hits	1757	Shared Neighborhood Hits	173
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PER3_HUMAN
NC score	0.049247 (rank : 798)	θ value	0.62314 (rank : 462)
Query Neighborhood Hits	812	Target Neighborhood Hits	479	Shared Neighborhood Hits	121
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CNTRB_MOUSE
NC score	0.049044 (rank : 799)	θ value	0.47712 (rank : 440)
Query Neighborhood Hits	812	Target Neighborhood Hits	1029	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CRKL_MOUSE
NC score	0.049003 (rank : 800)	θ value	2.36792 (rank : 576)
Query Neighborhood Hits	812	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

FGFR3_HUMAN
NC score	0.049002 (rank : 801)	θ value	3.0926 (rank : 617)
Query Neighborhood Hits	812	Target Neighborhood Hits	1042	Shared Neighborhood Hits	66
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

PDC6I_MOUSE
NC score	0.048380 (rank : 802)	θ value	5.27518 (rank : 716)
Query Neighborhood Hits	812	Target Neighborhood Hits	275	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

BIN1_HUMAN
NC score	0.047931 (rank : 803)	θ value	6.88961 (rank : 735)
Query Neighborhood Hits	812	Target Neighborhood Hits	335	Shared Neighborhood Hits	95
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

ARMX2_MOUSE
NC score	0.047796 (rank : 804)	θ value	3.0926 (rank : 603)
Query Neighborhood Hits	812	Target Neighborhood Hits	349	Shared Neighborhood Hits	96
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

IF4G1_MOUSE
NC score	0.047404 (rank : 805)	θ value	4.03905 (rank : 663)
Query Neighborhood Hits	812	Target Neighborhood Hits	534	Shared Neighborhood Hits	134
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

ULK1_MOUSE
NC score	0.046756 (rank : 806)	θ value	0.125558 (rank : 376)
Query Neighborhood Hits	812	Target Neighborhood Hits	1214	Shared Neighborhood Hits	164
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

GRAP2_HUMAN
NC score	0.046533 (rank : 807)	θ value	1.06291 (rank : 495)
Query Neighborhood Hits	812	Target Neighborhood Hits	304	Shared Neighborhood Hits	64
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

PDZD2_HUMAN
NC score	0.046512 (rank : 808)	θ value	2.36792 (rank : 586)
Query Neighborhood Hits	812	Target Neighborhood Hits	772	Shared Neighborhood Hits	153
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GRAP2_MOUSE
NC score	0.046437 (rank : 809)	θ value	1.06291 (rank : 496)
Query Neighborhood Hits	812	Target Neighborhood Hits	297	Shared Neighborhood Hits	62
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ITSN2_MOUSE
NC score	0.045122 (rank : 810)	θ value	1.06291 (rank : 499)
Query Neighborhood Hits	812	Target Neighborhood Hits	1371	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RANB9_HUMAN
NC score	0.044886 (rank : 811)	θ value	1.06291 (rank : 502)
Query Neighborhood Hits	812	Target Neighborhood Hits	179	Shared Neighborhood Hits	74
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

ASTL_HUMAN
NC score	0.044885 (rank : 812)	θ value	0.365318 (rank : 411)
Query Neighborhood Hits	812	Target Neighborhood Hits	252	Shared Neighborhood Hits	77
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

RAI1_MOUSE
NC score	0.044790 (rank : 813)	θ value	1.06291 (rank : 501)
Query Neighborhood Hits	812	Target Neighborhood Hits	344	Shared Neighborhood Hits	83
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RUSC2_MOUSE
NC score	0.044620 (rank : 814)	θ value	0.0961366 (rank : 369)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	96
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

STAC3_HUMAN
NC score	0.044548 (rank : 815)	θ value	8.99809 (rank : 806)
Query Neighborhood Hits	812	Target Neighborhood Hits	228	Shared Neighborhood Hits	49
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

PDCD7_MOUSE
NC score	0.044493 (rank : 816)	θ value	1.38821 (rank : 527)
Query Neighborhood Hits	812	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

STAC3_MOUSE
NC score	0.044264 (rank : 817)	θ value	8.99809 (rank : 807)
Query Neighborhood Hits	812	Target Neighborhood Hits	232	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SF3B1_MOUSE
NC score	0.044108 (rank : 818)	θ value	3.0926 (rank : 642)
Query Neighborhood Hits	812	Target Neighborhood Hits	352	Shared Neighborhood Hits	80
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

LRSM1_HUMAN
NC score	0.044020 (rank : 819)	θ value	3.0926 (rank : 623)
Query Neighborhood Hits	812	Target Neighborhood Hits	1078	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SF3B1_HUMAN
NC score	0.043919 (rank : 820)	θ value	3.0926 (rank : 641)
Query Neighborhood Hits	812	Target Neighborhood Hits	341	Shared Neighborhood Hits	80
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CBX2_HUMAN
NC score	0.043603 (rank : 821)	θ value	0.813845 (rank : 468)
Query Neighborhood Hits	812	Target Neighborhood Hits	264	Shared Neighborhood Hits	76
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

TS13_MOUSE
NC score	0.043487 (rank : 822)	θ value	1.38821 (rank : 536)
Query Neighborhood Hits	812	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

LR37A_HUMAN
NC score	0.043462 (rank : 823)	θ value	2.36792 (rank : 583)
Query Neighborhood Hits	812	Target Neighborhood Hits	720	Shared Neighborhood Hits	128
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CO2A1_HUMAN
NC score	0.043411 (rank : 824)	θ value	3.0926 (rank : 610)
Query Neighborhood Hits	812	Target Neighborhood Hits	486	Shared Neighborhood Hits	138
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

PTN23_HUMAN
NC score	0.042923 (rank : 825)	θ value	4.03905 (rank : 678)
Query Neighborhood Hits	812	Target Neighborhood Hits	646	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

HSF1_MOUSE
NC score	0.042882 (rank : 826)	θ value	2.36792 (rank : 582)
Query Neighborhood Hits	812	Target Neighborhood Hits	267	Shared Neighborhood Hits	69
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

APC_HUMAN
NC score	0.042462 (rank : 827)	θ value	1.81305 (rank : 537)
Query Neighborhood Hits	812	Target Neighborhood Hits	603	Shared Neighborhood Hits	98
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

GRB2_HUMAN
NC score	0.042407 (rank : 828)	θ value	1.81305 (rank : 548)
Query Neighborhood Hits	812	Target Neighborhood Hits	310	Shared Neighborhood Hits	57
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

CO2A1_MOUSE
NC score	0.042344 (rank : 829)	θ value	0.47712 (rank : 441)
Query Neighborhood Hits	812	Target Neighborhood Hits	483	Shared Neighborhood Hits	122
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

IRS2_MOUSE
NC score	0.042171 (rank : 830)	θ value	1.81305 (rank : 550)
Query Neighborhood Hits	812	Target Neighborhood Hits	248	Shared Neighborhood Hits	91
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PER1_HUMAN
NC score	0.042034 (rank : 831)	θ value	1.81305 (rank : 556)
Query Neighborhood Hits	812	Target Neighborhood Hits	215	Shared Neighborhood Hits	69
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

SMRC2_HUMAN
NC score	0.041993 (rank : 832)	θ value	0.62314 (rank : 465)
Query Neighborhood Hits	812	Target Neighborhood Hits	499	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TENX_HUMAN
NC score	0.041964 (rank : 833)	θ value	8.99809 (rank : 808)
Query Neighborhood Hits	812	Target Neighborhood Hits	789	Shared Neighborhood Hits	87
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

BAZ2A_MOUSE
NC score	0.041913 (rank : 834)	θ value	6.88961 (rank : 734)
Query Neighborhood Hits	812	Target Neighborhood Hits	744	Shared Neighborhood Hits	149
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

RAI1_HUMAN
NC score	0.041859 (rank : 835)	θ value	1.38821 (rank : 530)
Query Neighborhood Hits	812	Target Neighborhood Hits	360	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ITSN2_HUMAN
NC score	0.041498 (rank : 836)	θ value	1.06291 (rank : 498)
Query Neighborhood Hits	812	Target Neighborhood Hits	1173	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

GRB2_MOUSE
NC score	0.041420 (rank : 837)	θ value	3.0926 (rank : 619)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	57
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

AUTS2_HUMAN
NC score	0.041374 (rank : 838)	θ value	6.88961 (rank : 732)
Query Neighborhood Hits	812	Target Neighborhood Hits	342	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

IL4RA_MOUSE
NC score	0.041255 (rank : 839)	θ value	0.813845 (rank : 472)
Query Neighborhood Hits	812	Target Neighborhood Hits	194	Shared Neighborhood Hits	58
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

SPEG_MOUSE
NC score	0.041235 (rank : 840)	θ value	0.0113563 (rank : 312)
Query Neighborhood Hits	812	Target Neighborhood Hits	1959	Shared Neighborhood Hits	249
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GNAS1_MOUSE
NC score	0.041113 (rank : 841)	θ value	2.36792 (rank : 579)
Query Neighborhood Hits	812	Target Neighborhood Hits	651	Shared Neighborhood Hits	167
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CGRE1_HUMAN
NC score	0.040941 (rank : 842)	θ value	1.81305 (rank : 542)
Query Neighborhood Hits	812	Target Neighborhood Hits	354	Shared Neighborhood Hits	66
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CO9A1_MOUSE
NC score	0.040887 (rank : 843)	θ value	0.163984 (rank : 381)
Query Neighborhood Hits	812	Target Neighborhood Hits	477	Shared Neighborhood Hits	112
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ULK1_HUMAN
NC score	0.040700 (rank : 844)	θ value	3.0926 (rank : 647)
Query Neighborhood Hits	812	Target Neighborhood Hits	1121	Shared Neighborhood Hits	151
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CO1A2_HUMAN
NC score	0.040625 (rank : 845)	θ value	4.03905 (rank : 654)
Query Neighborhood Hits	812	Target Neighborhood Hits	329	Shared Neighborhood Hits	87
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

EP400_MOUSE
NC score	0.040579 (rank : 846)	θ value	1.38821 (rank : 517)
Query Neighborhood Hits	812	Target Neighborhood Hits	592	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

CO4A1_MOUSE
NC score	0.040553 (rank : 847)	θ value	6.88961 (rank : 737)
Query Neighborhood Hits	812	Target Neighborhood Hits	450	Shared Neighborhood Hits	121
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

SRBS1_HUMAN
NC score	0.040477 (rank : 848)	θ value	6.88961 (rank : 760)
Query Neighborhood Hits	812	Target Neighborhood Hits	396	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PAK4_MOUSE
NC score	0.040232 (rank : 849)	θ value	0.365318 (rank : 422)
Query Neighborhood Hits	812	Target Neighborhood Hits	1098	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SNIP_HUMAN
NC score	0.040227 (rank : 850)	θ value	1.81305 (rank : 563)
Query Neighborhood Hits	812	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

LRSM1_MOUSE
NC score	0.040140 (rank : 851)	θ value	8.99809 (rank : 790)
Query Neighborhood Hits	812	Target Neighborhood Hits	874	Shared Neighborhood Hits	57
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

LTB1L_HUMAN
NC score	0.039740 (rank : 852)	θ value	0.62314 (rank : 460)
Query Neighborhood Hits	812	Target Neighborhood Hits	553	Shared Neighborhood Hits	66
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SC24D_HUMAN
NC score	0.039721 (rank : 853)	θ value	2.36792 (rank : 589)
Query Neighborhood Hits	812	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

ZDHC8_MOUSE
NC score	0.039709 (rank : 854)	θ value	0.813845 (rank : 479)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	77
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

PGCA_HUMAN
NC score	0.039489 (rank : 855)	θ value	3.0926 (rank : 634)
Query Neighborhood Hits	812	Target Neighborhood Hits	821	Shared Neighborhood Hits	121
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

JIP3_HUMAN
NC score	0.039397 (rank : 856)	θ value	1.81305 (rank : 552)
Query Neighborhood Hits	812	Target Neighborhood Hits	1039	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CO9A1_HUMAN
NC score	0.039342 (rank : 857)	θ value	0.47712 (rank : 442)
Query Neighborhood Hits	812	Target Neighborhood Hits	420	Shared Neighborhood Hits	96
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

RFIP1_HUMAN
NC score	0.039198 (rank : 858)	θ value	6.88961 (rank : 754)
Query Neighborhood Hits	812	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

ZIM10_HUMAN
NC score	0.038940 (rank : 859)	θ value	1.81305 (rank : 569)
Query Neighborhood Hits	812	Target Neighborhood Hits	577	Shared Neighborhood Hits	152
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

EP400_HUMAN
NC score	0.038876 (rank : 860)	θ value	4.03905 (rank : 659)
Query Neighborhood Hits	812	Target Neighborhood Hits	556	Shared Neighborhood Hits	120
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

RIMB1_MOUSE
NC score	0.038727 (rank : 861)	θ value	2.36792 (rank : 588)
Query Neighborhood Hits	812	Target Neighborhood Hits	1376	Shared Neighborhood Hits	164
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

LTB1S_HUMAN
NC score	0.038304 (rank : 862)	θ value	0.62314 (rank : 461)
Query Neighborhood Hits	812	Target Neighborhood Hits	502	Shared Neighborhood Hits	52
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LSD1_HUMAN
NC score	0.038073 (rank : 863)	θ value	3.0926 (rank : 624)
Query Neighborhood Hits	812	Target Neighborhood Hits	455	Shared Neighborhood Hits	103
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

GON4L_HUMAN
NC score	0.037940 (rank : 864)	θ value	0.47712 (rank : 447)
Query Neighborhood Hits	812	Target Neighborhood Hits	555	Shared Neighborhood Hits	87
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

RTN1_HUMAN
NC score	0.037851 (rank : 865)	θ value	0.62314 (rank : 464)
Query Neighborhood Hits	812	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SRBP1_HUMAN
NC score	0.037849 (rank : 866)	θ value	1.81305 (rank : 565)
Query Neighborhood Hits	812	Target Neighborhood Hits	225	Shared Neighborhood Hits	57
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

GA2L1_HUMAN
NC score	0.036556 (rank : 867)	θ value	1.06291 (rank : 493)
Query Neighborhood Hits	812	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

RSMN_HUMAN
NC score	0.036405 (rank : 868)	θ value	4.03905 (rank : 680)
Query Neighborhood Hits	812	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.036405 (rank : 869)	θ value	4.03905 (rank : 681)
Query Neighborhood Hits	812	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

MAGD4_HUMAN
NC score	0.036343 (rank : 870)	θ value	0.0193708 (rank : 319)
Query Neighborhood Hits	812	Target Neighborhood Hits	338	Shared Neighborhood Hits	83
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

CUTL1_MOUSE
NC score	0.036253 (rank : 871)	θ value	0.62314 (rank : 457)
Query Neighborhood Hits	812	Target Neighborhood Hits	1620	Shared Neighborhood Hits	143
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

BANK1_MOUSE
NC score	0.036241 (rank : 872)	θ value	4.03905 (rank : 651)
Query Neighborhood Hits	812	Target Neighborhood Hits	63	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

CONA1_MOUSE
NC score	0.035598 (rank : 873)	θ value	1.38821 (rank : 514)
Query Neighborhood Hits	812	Target Neighborhood Hits	254	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

OSBP2_HUMAN
NC score	0.035418 (rank : 874)	θ value	0.365318 (rank : 421)
Query Neighborhood Hits	812	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

CONA1_HUMAN
NC score	0.035207 (rank : 875)	θ value	0.47712 (rank : 443)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	82
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

VGF_HUMAN
NC score	0.035111 (rank : 876)	θ value	2.36792 (rank : 598)
Query Neighborhood Hits	812	Target Neighborhood Hits	167	Shared Neighborhood Hits	34
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

NCOA2_HUMAN
NC score	0.035022 (rank : 877)	θ value	0.0252991 (rank : 331)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	60
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

COJA1_HUMAN
NC score	0.034735 (rank : 878)	θ value	8.99809 (rank : 775)
Query Neighborhood Hits	812	Target Neighborhood Hits	323	Shared Neighborhood Hits	82
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

PTN23_MOUSE
NC score	0.034217 (rank : 879)	θ value	1.38821 (rank : 529)
Query Neighborhood Hits	812	Target Neighborhood Hits	726	Shared Neighborhood Hits	146
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

LTB1L_MOUSE
NC score	0.034138 (rank : 880)	θ value	8.99809 (rank : 791)
Query Neighborhood Hits	812	Target Neighborhood Hits	514	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ASXL1_HUMAN
NC score	0.034032 (rank : 881)	θ value	0.47712 (rank : 433)
Query Neighborhood Hits	812	Target Neighborhood Hits	260	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CUTL2_HUMAN
NC score	0.033929 (rank : 882)	θ value	4.03905 (rank : 656)
Query Neighborhood Hits	812	Target Neighborhood Hits	906	Shared Neighborhood Hits	124
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

LTB1S_MOUSE
NC score	0.033923 (rank : 883)	θ value	8.99809 (rank : 792)
Query Neighborhood Hits	812	Target Neighborhood Hits	479	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LBXCO_HUMAN
NC score	0.033824 (rank : 884)	θ value	3.0926 (rank : 622)
Query Neighborhood Hits	812	Target Neighborhood Hits	167	Shared Neighborhood Hits	43
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

CO5A3_HUMAN
NC score	0.033450 (rank : 885)	θ value	8.99809 (rank : 773)
Query Neighborhood Hits	812	Target Neighborhood Hits	433	Shared Neighborhood Hits	115
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

TNIK_HUMAN
NC score	0.033220 (rank : 886)	θ value	0.0252991 (rank : 334)
Query Neighborhood Hits	812	Target Neighborhood Hits	1570	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

INP5E_HUMAN
NC score	0.032919 (rank : 887)	θ value	4.03905 (rank : 664)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

OBF1_HUMAN
NC score	0.032915 (rank : 888)	θ value	6.88961 (rank : 751)
Query Neighborhood Hits	812	Target Neighborhood Hits	203	Shared Neighborhood Hits	59
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

ZAR1_HUMAN
NC score	0.032805 (rank : 889)	θ value	1.81305 (rank : 568)
Query Neighborhood Hits	812	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

PHC2_MOUSE
NC score	0.032681 (rank : 890)	θ value	0.279714 (rank : 408)
Query Neighborhood Hits	812	Target Neighborhood Hits	156	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

CJ026_MOUSE
NC score	0.032400 (rank : 891)	θ value	0.62314 (rank : 454)
Query Neighborhood Hits	812	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

M3K1_MOUSE
NC score	0.032365 (rank : 892)	θ value	1.38821 (rank : 524)
Query Neighborhood Hits	812	Target Neighborhood Hits	952	Shared Neighborhood Hits	78
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

BPTF_HUMAN
NC score	0.032298 (rank : 893)	θ value	3.0926 (rank : 607)
Query Neighborhood Hits	812	Target Neighborhood Hits	786	Shared Neighborhood Hits	91
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SCAR3_MOUSE
NC score	0.032261 (rank : 894)	θ value	1.81305 (rank : 561)
Query Neighborhood Hits	812	Target Neighborhood Hits	239	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

MAML1_MOUSE
NC score	0.032223 (rank : 895)	θ value	5.27518 (rank : 710)
Query Neighborhood Hits	812	Target Neighborhood Hits	279	Shared Neighborhood Hits	84
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MINK1_MOUSE
NC score	0.032155 (rank : 896)	θ value	5.27518 (rank : 712)
Query Neighborhood Hits	812	Target Neighborhood Hits	1451	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SF3B4_HUMAN
NC score	0.032117 (rank : 897)	θ value	4.03905 (rank : 683)
Query Neighborhood Hits	812	Target Neighborhood Hits	445	Shared Neighborhood Hits	97
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

MK15_HUMAN
NC score	0.031710 (rank : 898)	θ value	0.0736092 (rank : 355)
Query Neighborhood Hits	812	Target Neighborhood Hits	1038	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

C1QR1_HUMAN
NC score	0.031691 (rank : 899)	θ value	8.99809 (rank : 769)
Query Neighborhood Hits	812	Target Neighborhood Hits	493	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

TM131_MOUSE
NC score	0.031667 (rank : 900)	θ value	5.27518 (rank : 724)
Query Neighborhood Hits	812	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

GAK_HUMAN
NC score	0.031433 (rank : 901)	θ value	5.27518 (rank : 704)
Query Neighborhood Hits	812	Target Neighborhood Hits	1028	Shared Neighborhood Hits	116
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GR65_HUMAN
NC score	0.031310 (rank : 902)	θ value	2.36792 (rank : 580)
Query Neighborhood Hits	812	Target Neighborhood Hits	148	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

MEF2B_MOUSE
NC score	0.031109 (rank : 903)	θ value	1.81305 (rank : 554)
Query Neighborhood Hits	812	Target Neighborhood Hits	218	Shared Neighborhood Hits	67
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

RSMB_HUMAN
NC score	0.031022 (rank : 904)	θ value	6.88961 (rank : 757)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

M3K2_MOUSE
NC score	0.030790 (rank : 905)	θ value	4.03905 (rank : 667)
Query Neighborhood Hits	812	Target Neighborhood Hits	846	Shared Neighborhood Hits	65
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MYST3_HUMAN
NC score	0.030570 (rank : 906)	θ value	3.0926 (rank : 628)
Query Neighborhood Hits	812	Target Neighborhood Hits	772	Shared Neighborhood Hits	104
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

CO9A2_HUMAN
NC score	0.030550 (rank : 907)	θ value	8.99809 (rank : 774)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	65
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CBLB_MOUSE
NC score	0.030430 (rank : 908)	θ value	0.0736092 (rank : 348)
Query Neighborhood Hits	812	Target Neighborhood Hits	277	Shared Neighborhood Hits	43
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

MYO9B_HUMAN
NC score	0.030170 (rank : 909)	θ value	0.000158464 (rank : 249)
Query Neighborhood Hits	812	Target Neighborhood Hits	641	Shared Neighborhood Hits	112
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MAST3_HUMAN
NC score	0.030149 (rank : 910)	θ value	6.88961 (rank : 747)
Query Neighborhood Hits	812	Target Neighborhood Hits	1128	Shared Neighborhood Hits	129
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

HCN2_HUMAN
NC score	0.029863 (rank : 911)	θ value	8.99809 (rank : 788)
Query Neighborhood Hits	812	Target Neighborhood Hits	369	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

ATF2_HUMAN
NC score	0.029768 (rank : 912)	θ value	1.81305 (rank : 538)
Query Neighborhood Hits	812	Target Neighborhood Hits	402	Shared Neighborhood Hits	61
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

TAF6_MOUSE
NC score	0.029746 (rank : 913)	θ value	6.88961 (rank : 763)
Query Neighborhood Hits	812	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

TRAK2_HUMAN
NC score	0.029469 (rank : 914)	θ value	5.27518 (rank : 725)
Query Neighborhood Hits	812	Target Neighborhood Hits	476	Shared Neighborhood Hits	44
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

NCOA3_MOUSE
NC score	0.029395 (rank : 915)	θ value	0.21417 (rank : 394)
Query Neighborhood Hits	812	Target Neighborhood Hits	203	Shared Neighborhood Hits	49
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

DLG5_HUMAN
NC score	0.029247 (rank : 916)	θ value	1.38821 (rank : 516)
Query Neighborhood Hits	812	Target Neighborhood Hits	1088	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

RTN1_MOUSE
NC score	0.029220 (rank : 917)	θ value	4.03905 (rank : 682)
Query Neighborhood Hits	812	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

OBSCN_HUMAN
NC score	0.029167 (rank : 918)	θ value	3.0926 (rank : 630)
Query Neighborhood Hits	812	Target Neighborhood Hits	1931	Shared Neighborhood Hits	222
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ZYX_HUMAN
NC score	0.028883 (rank : 919)	θ value	3.0926 (rank : 649)
Query Neighborhood Hits	812	Target Neighborhood Hits	387	Shared Neighborhood Hits	80
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

BRSK2_HUMAN
NC score	0.028759 (rank : 920)	θ value	8.99809 (rank : 768)
Query Neighborhood Hits	812	Target Neighborhood Hits	897	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

ATF2_MOUSE
NC score	0.028718 (rank : 921)	θ value	1.81305 (rank : 539)
Query Neighborhood Hits	812	Target Neighborhood Hits	397	Shared Neighborhood Hits	62
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

FRS3_MOUSE
NC score	0.028702 (rank : 922)	θ value	0.0961366 (rank : 364)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	54
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

YETS2_MOUSE
NC score	0.028671 (rank : 923)	θ value	3.0926 (rank : 648)
Query Neighborhood Hits	812	Target Neighborhood Hits	278	Shared Neighborhood Hits	69
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ALMS1_HUMAN
NC score	0.028532 (rank : 924)	θ value	1.38821 (rank : 511)
Query Neighborhood Hits	812	Target Neighborhood Hits	356	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

R3HD1_HUMAN
NC score	0.028304 (rank : 925)	θ value	3.0926 (rank : 639)
Query Neighborhood Hits	812	Target Neighborhood Hits	203	Shared Neighborhood Hits	51
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

TENS4_MOUSE
NC score	0.028300 (rank : 926)	θ value	1.81305 (rank : 566)
Query Neighborhood Hits	812	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

SVIL_MOUSE
NC score	0.027938 (rank : 927)	θ value	1.38821 (rank : 533)
Query Neighborhood Hits	812	Target Neighborhood Hits	439	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

IF4B_MOUSE
NC score	0.027832 (rank : 928)	θ value	6.88961 (rank : 745)
Query Neighborhood Hits	812	Target Neighborhood Hits	368	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_HUMAN
NC score	0.027115 (rank : 929)	θ value	3.0926 (rank : 621)
Query Neighborhood Hits	812	Target Neighborhood Hits	417	Shared Neighborhood Hits	75
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

DEN1A_MOUSE
NC score	0.027081 (rank : 930)	θ value	8.99809 (rank : 780)
Query Neighborhood Hits	812	Target Neighborhood Hits	178	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

CAC1G_HUMAN
NC score	0.027018 (rank : 931)	θ value	1.81305 (rank : 541)
Query Neighborhood Hits	812	Target Neighborhood Hits	587	Shared Neighborhood Hits	148
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

PF21B_HUMAN
NC score	0.026998 (rank : 932)	θ value	3.0926 (rank : 633)
Query Neighborhood Hits	812	Target Neighborhood Hits	197	Shared Neighborhood Hits	38
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
NC score	0.026956 (rank : 933)	θ value	6.88961 (rank : 752)
Query Neighborhood Hits	812	Target Neighborhood Hits	278	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

DNMT1_HUMAN
NC score	0.026934 (rank : 934)	θ value	8.99809 (rank : 781)
Query Neighborhood Hits	812	Target Neighborhood Hits	401	Shared Neighborhood Hits	45
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SIN3A_MOUSE
NC score	0.026888 (rank : 935)	θ value	1.38821 (rank : 532)
Query Neighborhood Hits	812	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

TINF2_HUMAN
NC score	0.026746 (rank : 936)	θ value	0.365318 (rank : 428)
Query Neighborhood Hits	812	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

GCP60_HUMAN
NC score	0.026730 (rank : 937)	θ value	1.06291 (rank : 494)
Query Neighborhood Hits	812	Target Neighborhood Hits	419	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

IQEC3_MOUSE
NC score	0.026634 (rank : 938)	θ value	1.81305 (rank : 549)
Query Neighborhood Hits	812	Target Neighborhood Hits	274	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CMGA_MOUSE
NC score	0.026099 (rank : 939)	θ value	8.99809 (rank : 771)
Query Neighborhood Hits	812	Target Neighborhood Hits	172	Shared Neighborhood Hits	31
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

IRX5_MOUSE
NC score	0.025898 (rank : 940)	θ value	0.0563607 (rank : 345)
Query Neighborhood Hits	812	Target Neighborhood Hits	324	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

SIN3A_HUMAN
NC score	0.025487 (rank : 941)	θ value	4.03905 (rank : 684)
Query Neighborhood Hits	812	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

DCC_MOUSE
NC score	0.025329 (rank : 942)	θ value	1.38821 (rank : 515)
Query Neighborhood Hits	812	Target Neighborhood Hits	896	Shared Neighborhood Hits	135
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

K0423_HUMAN
NC score	0.024942 (rank : 943)	θ value	1.38821 (rank : 520)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TBCD4_MOUSE
NC score	0.024807 (rank : 944)	θ value	4.03905 (rank : 685)
Query Neighborhood Hits	812	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

PER2_MOUSE
NC score	0.024764 (rank : 945)	θ value	1.81305 (rank : 557)
Query Neighborhood Hits	812	Target Neighborhood Hits	325	Shared Neighborhood Hits	64
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

MYO1F_HUMAN
NC score	0.024607 (rank : 946)	θ value	1.81305 (rank : 555)
Query Neighborhood Hits	812	Target Neighborhood Hits	275	Shared Neighborhood Hits	72
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SOCS7_MOUSE
NC score	0.024409 (rank : 947)	θ value	1.81305 (rank : 564)
Query Neighborhood Hits	812	Target Neighborhood Hits	154	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

CBLB_HUMAN
NC score	0.024199 (rank : 948)	θ value	0.47712 (rank : 434)
Query Neighborhood Hits	812	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

WDR33_HUMAN
NC score	0.024171 (rank : 949)	θ value	2.36792 (rank : 599)
Query Neighborhood Hits	812	Target Neighborhood Hits	638	Shared Neighborhood Hits	108
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

NU153_HUMAN
NC score	0.024021 (rank : 950)	θ value	4.03905 (rank : 672)
Query Neighborhood Hits	812	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

CNOT4_MOUSE
NC score	0.023883 (rank : 951)	θ value	5.27518 (rank : 696)
Query Neighborhood Hits	812	Target Neighborhood Hits	277	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

PKHG4_HUMAN
NC score	0.023867 (rank : 952)	θ value	3.0926 (rank : 636)
Query Neighborhood Hits	812	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PER2_HUMAN
NC score	0.023843 (rank : 953)	θ value	3.0926 (rank : 632)
Query Neighborhood Hits	812	Target Neighborhood Hits	170	Shared Neighborhood Hits	39
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

MYO15_MOUSE
NC score	0.023804 (rank : 954)	θ value	4.03905 (rank : 670)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

AFF3_HUMAN
NC score	0.023587 (rank : 955)	θ value	4.03905 (rank : 650)
Query Neighborhood Hits	812	Target Neighborhood Hits	190	Shared Neighborhood Hits	48
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

ERCC5_MOUSE
NC score	0.023361 (rank : 956)	θ value	0.47712 (rank : 446)
Query Neighborhood Hits	812	Target Neighborhood Hits	206	Shared Neighborhood Hits	23
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

RFIP4_HUMAN
NC score	0.023343 (rank : 957)	θ value	6.88961 (rank : 756)
Query Neighborhood Hits	812	Target Neighborhood Hits	785	Shared Neighborhood Hits	59
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

IRS1_HUMAN
NC score	0.023096 (rank : 958)	θ value	0.279714 (rank : 403)
Query Neighborhood Hits	812	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PO6F2_MOUSE
NC score	0.022862 (rank : 959)	θ value	8.99809 (rank : 797)
Query Neighborhood Hits	812	Target Neighborhood Hits	639	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

MACF4_HUMAN
NC score	0.022585 (rank : 960)	θ value	3.0926 (rank : 626)
Query Neighborhood Hits	812	Target Neighborhood Hits	1321	Shared Neighborhood Hits	94
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYO1E_HUMAN
NC score	0.022529 (rank : 961)	θ value	0.279714 (rank : 406)
Query Neighborhood Hits	812	Target Neighborhood Hits	293	Shared Neighborhood Hits	66
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

GNDS_HUMAN
NC score	0.022385 (rank : 962)	θ value	4.03905 (rank : 661)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	47
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

LBXCO_MOUSE
NC score	0.021821 (rank : 963)	θ value	1.38821 (rank : 522)
Query Neighborhood Hits	812	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

SOS1_MOUSE
NC score	0.021679 (rank : 964)	θ value	6.88961 (rank : 759)
Query Neighborhood Hits	812	Target Neighborhood Hits	281	Shared Neighborhood Hits	54
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOX13_MOUSE
NC score	0.021519 (rank : 965)	θ value	3.0926 (rank : 644)
Query Neighborhood Hits	812	Target Neighborhood Hits	495	Shared Neighborhood Hits	104
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

ZN409_HUMAN
NC score	0.021517 (rank : 966)	θ value	0.163984 (rank : 388)
Query Neighborhood Hits	812	Target Neighborhood Hits	842	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

DTX1_MOUSE
NC score	0.021451 (rank : 967)	θ value	5.27518 (rank : 698)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

FOG1_MOUSE
NC score	0.021394 (rank : 968)	θ value	1.06291 (rank : 491)
Query Neighborhood Hits	812	Target Neighborhood Hits	1237	Shared Neighborhood Hits	188
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

TULP4_MOUSE
NC score	0.020971 (rank : 969)	θ value	0.813845 (rank : 477)
Query Neighborhood Hits	812	Target Neighborhood Hits	247	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

FRS3_HUMAN
NC score	0.020958 (rank : 970)	θ value	5.27518 (rank : 703)
Query Neighborhood Hits	812	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

OTU7B_HUMAN
NC score	0.020877 (rank : 971)	θ value	0.0961366 (rank : 367)
Query Neighborhood Hits	812	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

TOPB1_MOUSE
NC score	0.020876 (rank : 972)	θ value	0.813845 (rank : 476)
Query Neighborhood Hits	812	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

NCOA1_HUMAN
NC score	0.020858 (rank : 973)	θ value	0.47712 (rank : 448)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

SYNE1_HUMAN
NC score	0.020683 (rank : 974)	θ value	2.36792 (rank : 593)
Query Neighborhood Hits	812	Target Neighborhood Hits	1484	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

RHG09_HUMAN
NC score	0.020511 (rank : 975)	θ value	1.38821 (rank : 531)
Query Neighborhood Hits	812	Target Neighborhood Hits	186	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

FA61A_MOUSE
NC score	0.020236 (rank : 976)	θ value	1.06291 (rank : 489)
Query Neighborhood Hits	812	Target Neighborhood Hits	81	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

COG8_HUMAN
NC score	0.020199 (rank : 977)	θ value	1.81305 (rank : 545)
Query Neighborhood Hits	812	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q96MW5, Q8WVV6, Q9H6F8	Gene names	COG8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

SPRE3_MOUSE
NC score	0.019855 (rank : 978)	θ value	5.27518 (rank : 720)
Query Neighborhood Hits	812	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

LRC56_HUMAN
NC score	0.019714 (rank : 979)	θ value	5.27518 (rank : 709)
Query Neighborhood Hits	812	Target Neighborhood Hits	165	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

PAR6A_HUMAN
NC score	0.019588 (rank : 980)	θ value	0.279714 (rank : 407)
Query Neighborhood Hits	812	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

RFIP1_MOUSE
NC score	0.019348 (rank : 981)	θ value	6.88961 (rank : 755)
Query Neighborhood Hits	812	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SMCA2_HUMAN
NC score	0.019193 (rank : 982)	θ value	1.06291 (rank : 505)
Query Neighborhood Hits	812	Target Neighborhood Hits	503	Shared Neighborhood Hits	89
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

C1QA_HUMAN
NC score	0.018839 (rank : 983)	θ value	1.06291 (rank : 485)
Query Neighborhood Hits	812	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

TTC28_HUMAN
NC score	0.018799 (rank : 984)	θ value	5.27518 (rank : 727)
Query Neighborhood Hits	812	Target Neighborhood Hits	271	Shared Neighborhood Hits	45
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

FHOD1_HUMAN
NC score	0.018796 (rank : 985)	θ value	8.99809 (rank : 784)
Query Neighborhood Hits	812	Target Neighborhood Hits	184	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

NFAC4_HUMAN
NC score	0.018721 (rank : 986)	θ value	4.03905 (rank : 671)
Query Neighborhood Hits	812	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

CSTFT_MOUSE
NC score	0.018634 (rank : 987)	θ value	4.03905 (rank : 655)
Query Neighborhood Hits	812	Target Neighborhood Hits	356	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

FA61A_HUMAN
NC score	0.018490 (rank : 988)	θ value	1.38821 (rank : 518)
Query Neighborhood Hits	812	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q8ND56, Q76LX7, Q96AR3, Q96K73, Q96SN5, Q9UFR3	Gene names	FAM61A, C19orf13
Domain Architecture	No domain graphic available
Description	Protein FAM61A (Putative alpha synuclein-binding protein) (AlphaSNBP).

DMRTD_MOUSE
NC score	0.018414 (rank : 989)	θ value	3.0926 (rank : 614)
Query Neighborhood Hits	812	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

RBNS5_HUMAN
NC score	0.018362 (rank : 990)	θ value	5.27518 (rank : 719)
Query Neighborhood Hits	812	Target Neighborhood Hits	242	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

K1849_MOUSE
NC score	0.018297 (rank : 991)	θ value	0.62314 (rank : 459)
Query Neighborhood Hits	812	Target Neighborhood Hits	335	Shared Neighborhood Hits	69
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZN687_HUMAN
NC score	0.018270 (rank : 992)	θ value	0.21417 (rank : 399)
Query Neighborhood Hits	812	Target Neighborhood Hits	1244	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ETV3_HUMAN
NC score	0.018179 (rank : 993)	θ value	0.163984 (rank : 384)
Query Neighborhood Hits	812	Target Neighborhood Hits	312	Shared Neighborhood Hits	60
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

TNR8_HUMAN
NC score	0.018111 (rank : 994)	θ value	0.365318 (rank : 429)
Query Neighborhood Hits	812	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TF3C1_HUMAN
NC score	0.018064 (rank : 995)	θ value	0.47712 (rank : 453)
Query Neighborhood Hits	812	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

MACF1_HUMAN
NC score	0.018036 (rank : 996)	θ value	3.0926 (rank : 625)
Query Neighborhood Hits	812	Target Neighborhood Hits	1341	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

FOG1_HUMAN
NC score	0.017878 (rank : 997)	θ value	1.06291 (rank : 490)
Query Neighborhood Hits	812	Target Neighborhood Hits	981	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

DACT1_MOUSE
NC score	0.017378 (rank : 998)	θ value	1.06291 (rank : 488)
Query Neighborhood Hits	812	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

PHLPP_HUMAN
NC score	0.017329 (rank : 999)	θ value	3.0926 (rank : 635)
Query Neighborhood Hits	812	Target Neighborhood Hits	604	Shared Neighborhood Hits	101
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

RP1L1_MOUSE
NC score	0.017209 (rank : 1000)	θ value	3.0926 (rank : 640)
Query Neighborhood Hits	812	Target Neighborhood Hits	170	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

AMPD2_HUMAN
NC score	0.017021 (rank : 1001)	θ value	0.21417 (rank : 389)
Query Neighborhood Hits	812	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q01433, Q14856, Q14857, Q16686, Q16687, Q16688, Q16729, Q96IA1, Q9UDX8, Q9UDX9, Q9UMU4	Gene names	AMPD2
Domain Architecture
Description	AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L).

SOS1_HUMAN
NC score	0.017003 (rank : 1002)	θ value	6.88961 (rank : 758)
Query Neighborhood Hits	812	Target Neighborhood Hits	274	Shared Neighborhood Hits	52
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

ZFHX2_HUMAN
NC score	0.016785 (rank : 1003)	θ value	0.365318 (rank : 432)
Query Neighborhood Hits	812	Target Neighborhood Hits	1178	Shared Neighborhood Hits	118
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

SIX5_HUMAN
NC score	0.016762 (rank : 1004)	θ value	2.36792 (rank : 590)
Query Neighborhood Hits	812	Target Neighborhood Hits	386	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

TFE2_HUMAN
NC score	0.016705 (rank : 1005)	θ value	0.21417 (rank : 397)
Query Neighborhood Hits	812	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

GAB2_MOUSE
NC score	0.016583 (rank : 1006)	θ value	6.88961 (rank : 741)
Query Neighborhood Hits	812	Target Neighborhood Hits	220	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

ODP2_HUMAN
NC score	0.016545 (rank : 1007)	θ value	1.06291 (rank : 500)
Query Neighborhood Hits	812	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

CNOT4_HUMAN
NC score	0.016342 (rank : 1008)	θ value	4.03905 (rank : 653)
Query Neighborhood Hits	812	Target Neighborhood Hits	207	Shared Neighborhood Hits	40
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

YBOX2_HUMAN
NC score	0.016337 (rank : 1009)	θ value	1.81305 (rank : 567)
Query Neighborhood Hits	812	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

DTX1_HUMAN
NC score	0.016271 (rank : 1010)	θ value	4.03905 (rank : 658)
Query Neighborhood Hits	812	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

CE016_HUMAN
NC score	0.016081 (rank : 1011)	θ value	3.0926 (rank : 609)
Query Neighborhood Hits	812	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

RHG12_MOUSE
NC score	0.015783 (rank : 1012)	θ value	1.81305 (rank : 559)
Query Neighborhood Hits	812	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

KCD18_HUMAN
NC score	0.015695 (rank : 1013)	θ value	1.38821 (rank : 521)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

MACF1_MOUSE
NC score	0.014879 (rank : 1014)	θ value	2.36792 (rank : 584)
Query Neighborhood Hits	812	Target Neighborhood Hits	1313	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

AMPD2_MOUSE
NC score	0.014832 (rank : 1015)	θ value	1.06291 (rank : 481)
Query Neighborhood Hits	812	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBT5, Q91YI2	Gene names	Ampd2
Domain Architecture	No domain graphic available
Description	AMP deaminase 2 (EC 3.5.4.6).

RHG12_HUMAN
NC score	0.014690 (rank : 1016)	θ value	4.03905 (rank : 679)
Query Neighborhood Hits	812	Target Neighborhood Hits	190	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

AUXI_HUMAN
NC score	0.014490 (rank : 1017)	θ value	0.365318 (rank : 412)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

FOXN1_MOUSE
NC score	0.014223 (rank : 1018)	θ value	2.36792 (rank : 578)
Query Neighborhood Hits	812	Target Neighborhood Hits	300	Shared Neighborhood Hits	70
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

HAIR_MOUSE
NC score	0.013866 (rank : 1019)	θ value	3.0926 (rank : 620)
Query Neighborhood Hits	812	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

SEM6B_MOUSE
NC score	0.013807 (rank : 1020)	θ value	0.279714 (rank : 409)
Query Neighborhood Hits	812	Target Neighborhood Hits	200	Shared Neighborhood Hits	54
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

YTHD1_HUMAN
NC score	0.013479 (rank : 1021)	θ value	5.27518 (rank : 730)
Query Neighborhood Hits	812	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

T240L_HUMAN
NC score	0.013439 (rank : 1022)	θ value	6.88961 (rank : 762)
Query Neighborhood Hits	812	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

MEFV_MOUSE
NC score	0.013275 (rank : 1023)	θ value	0.279714 (rank : 405)
Query Neighborhood Hits	812	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RECQ4_HUMAN
NC score	0.013146 (rank : 1024)	θ value	1.06291 (rank : 503)
Query Neighborhood Hits	812	Target Neighborhood Hits	177	Shared Neighborhood Hits	39
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

B4GT1_HUMAN
NC score	0.013131 (rank : 1025)	θ value	2.36792 (rank : 572)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	30
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CSTF2_HUMAN
NC score	0.012826 (rank : 1026)	θ value	0.163984 (rank : 382)
Query Neighborhood Hits	812	Target Neighborhood Hits	296	Shared Neighborhood Hits	42
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

YTHD2_HUMAN
NC score	0.012760 (rank : 1027)	θ value	2.36792 (rank : 600)
Query Neighborhood Hits	812	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

ZN185_HUMAN
NC score	0.012383 (rank : 1028)	θ value	6.88961 (rank : 766)
Query Neighborhood Hits	812	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

FREA_HUMAN
NC score	0.011625 (rank : 1029)	θ value	1.06291 (rank : 492)
Query Neighborhood Hits	812	Target Neighborhood Hits	205	Shared Neighborhood Hits	49
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

ITF2_HUMAN
NC score	0.011606 (rank : 1030)	θ value	4.03905 (rank : 665)
Query Neighborhood Hits	812	Target Neighborhood Hits	168	Shared Neighborhood Hits	22
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

LIMD1_HUMAN
NC score	0.011601 (rank : 1031)	θ value	0.0961366 (rank : 365)
Query Neighborhood Hits	812	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

FBX42_MOUSE
NC score	0.011116 (rank : 1032)	θ value	3.0926 (rank : 616)
Query Neighborhood Hits	812	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

CAC1B_MOUSE
NC score	0.010782 (rank : 1033)	θ value	0.279714 (rank : 401)
Query Neighborhood Hits	812	Target Neighborhood Hits	351	Shared Neighborhood Hits	67
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ZN516_MOUSE
NC score	0.010577 (rank : 1034)	θ value	4.03905 (rank : 689)
Query Neighborhood Hits	812	Target Neighborhood Hits	1197	Shared Neighborhood Hits	175
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

MYCL1_HUMAN
NC score	0.010418 (rank : 1035)	θ value	4.03905 (rank : 669)
Query Neighborhood Hits	812	Target Neighborhood Hits	146	Shared Neighborhood Hits	27
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MTFR1_MOUSE
NC score	0.010255 (rank : 1036)	θ value	3.0926 (rank : 627)
Query Neighborhood Hits	812	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MB2, Q9CQZ4	Gene names	Mtfr1, Kiaa0009
Domain Architecture	No domain graphic available
Description	Mitochondrial fission regulator 1.

JARD2_MOUSE
NC score	0.010098 (rank : 1037)	θ value	4.03905 (rank : 666)
Query Neighborhood Hits	812	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

TSH2_MOUSE
NC score	0.009996 (rank : 1038)	θ value	0.21417 (rank : 398)
Query Neighborhood Hits	812	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

TAF1C_MOUSE
NC score	0.009786 (rank : 1039)	θ value	5.27518 (rank : 722)
Query Neighborhood Hits	812	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

MYBPH_MOUSE
NC score	0.009704 (rank : 1040)	θ value	4.03905 (rank : 668)
Query Neighborhood Hits	812	Target Neighborhood Hits	290	Shared Neighborhood Hits	38
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

GP156_HUMAN
NC score	0.009697 (rank : 1041)	θ value	8.99809 (rank : 787)
Query Neighborhood Hits	812	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

DNM3A_MOUSE
NC score	0.009648 (rank : 1042)	θ value	6.88961 (rank : 739)
Query Neighborhood Hits	812	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DLG4_HUMAN
NC score	0.008375 (rank : 1043)	θ value	3.0926 (rank : 613)
Query Neighborhood Hits	812	Target Neighborhood Hits	286	Shared Neighborhood Hits	42
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GLUD1_MOUSE
NC score	0.008317 (rank : 1044)	θ value	8.99809 (rank : 786)
Query Neighborhood Hits	812	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

PAR6A_MOUSE
NC score	0.008206 (rank : 1045)	θ value	5.27518 (rank : 714)
Query Neighborhood Hits	812	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

RAVR1_MOUSE
NC score	0.008161 (rank : 1046)	θ value	8.99809 (rank : 799)
Query Neighborhood Hits	812	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

DLG1_MOUSE
NC score	0.008148 (rank : 1047)	θ value	4.03905 (rank : 657)
Query Neighborhood Hits	812	Target Neighborhood Hits	285	Shared Neighborhood Hits	44
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

TSH2_HUMAN
NC score	0.008134 (rank : 1048)	θ value	5.27518 (rank : 726)
Query Neighborhood Hits	812	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

DHX37_HUMAN
NC score	0.008007 (rank : 1049)	θ value	5.27518 (rank : 697)
Query Neighborhood Hits	812	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

KIFC3_HUMAN
NC score	0.007915 (rank : 1050)	θ value	5.27518 (rank : 708)
Query Neighborhood Hits	812	Target Neighborhood Hits	619	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

ARHG2_HUMAN
NC score	0.007854 (rank : 1051)	θ value	6.88961 (rank : 731)
Query Neighborhood Hits	812	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

MGR1_MOUSE
NC score	0.007813 (rank : 1052)	θ value	0.0736092 (rank : 354)
Query Neighborhood Hits	812	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

GP124_MOUSE
NC score	0.007568 (rank : 1053)	θ value	1.38821 (rank : 519)
Query Neighborhood Hits	812	Target Neighborhood Hits	423	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

FREA_MOUSE
NC score	0.007568 (rank : 1054)	θ value	3.0926 (rank : 618)
Query Neighborhood Hits	812	Target Neighborhood Hits	147	Shared Neighborhood Hits	31
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

PDLI5_HUMAN
NC score	0.007565 (rank : 1055)	θ value	5.27518 (rank : 717)
Query Neighborhood Hits	812	Target Neighborhood Hits	322	Shared Neighborhood Hits	43
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

HCN1_MOUSE
NC score	0.006974 (rank : 1056)	θ value	2.36792 (rank : 581)
Query Neighborhood Hits	812	Target Neighborhood Hits	172	Shared Neighborhood Hits	29
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HRSL5_HUMAN
NC score	0.006395 (rank : 1057)	θ value	6.88961 (rank : 743)
Query Neighborhood Hits	812	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

ESPL1_MOUSE
NC score	0.006200 (rank : 1058)	θ value	8.99809 (rank : 782)
Query Neighborhood Hits	812	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

PAX3_MOUSE
NC score	0.005739 (rank : 1059)	θ value	0.0961366 (rank : 368)
Query Neighborhood Hits	812	Target Neighborhood Hits	478	Shared Neighborhood Hits	39
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PAX3_HUMAN
NC score	0.005685 (rank : 1060)	θ value	0.125558 (rank : 374)
Query Neighborhood Hits	812	Target Neighborhood Hits	513	Shared Neighborhood Hits	46
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PHF1_HUMAN
NC score	0.005360 (rank : 1061)	θ value	4.03905 (rank : 674)
Query Neighborhood Hits	812	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

SALL3_HUMAN
NC score	0.005344 (rank : 1062)	θ value	0.163984 (rank : 386)
Query Neighborhood Hits	812	Target Neighborhood Hits	1066	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

PUNC_MOUSE
NC score	0.005141 (rank : 1063)	θ value	1.81305 (rank : 558)
Query Neighborhood Hits	812	Target Neighborhood Hits	501	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

NAGS_HUMAN
NC score	0.004952 (rank : 1064)	θ value	8.99809 (rank : 796)
Query Neighborhood Hits	812	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N159, Q8IWR4	Gene names	NAGS
Domain Architecture	No domain graphic available
Description	N-acetylglutamate synthase, mitochondrial precursor (EC 2.3.1.1) (Amino-acid acetyltransferase) [Contains: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form].

FBX18_MOUSE
NC score	0.004916 (rank : 1065)	θ value	6.88961 (rank : 740)
Query Neighborhood Hits	812	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2I9, Q8C444, Q99KS0, Q9CTC6, Q9QZG7	Gene names	Fbxo18, Fbh1, Fbx18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FETUB_MOUSE
NC score	0.004261 (rank : 1066)	θ value	8.99809 (rank : 783)
Query Neighborhood Hits	812	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

CCG8_MOUSE
NC score	0.004234 (rank : 1067)	θ value	3.0926 (rank : 608)
Query Neighborhood Hits	812	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHW2	Gene names	Cacng8
Domain Architecture
Description	Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage- gated calcium channel gamma-8 subunit).

ETV4_MOUSE
NC score	0.003707 (rank : 1068)	θ value	4.03905 (rank : 660)
Query Neighborhood Hits	812	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

CD45_HUMAN
NC score	0.003468 (rank : 1069)	θ value	2.36792 (rank : 574)
Query Neighborhood Hits	812	Target Neighborhood Hits	243	Shared Neighborhood Hits	34
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

LNX2_MOUSE
NC score	0.003331 (rank : 1070)	θ value	1.38821 (rank : 523)
Query Neighborhood Hits	812	Target Neighborhood Hits	407	Shared Neighborhood Hits	22
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

UB2J1_MOUSE
NC score	0.003253 (rank : 1071)	θ value	2.36792 (rank : 597)
Query Neighborhood Hits	812	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

TMG3_MOUSE
NC score	0.002214 (rank : 1072)	θ value	6.88961 (rank : 764)
Query Neighborhood Hits	812	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

MYST1_HUMAN
NC score	0.002155 (rank : 1073)	θ value	8.99809 (rank : 795)
Query Neighborhood Hits	812	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

NOS1_MOUSE
NC score	0.001442 (rank : 1074)	θ value	6.88961 (rank : 750)
Query Neighborhood Hits	812	Target Neighborhood Hits	155	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

CABP4_HUMAN
NC score	0.001319 (rank : 1075)	θ value	2.36792 (rank : 573)
Query Neighborhood Hits	812	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

SYT3_HUMAN
NC score	0.001128 (rank : 1076)	θ value	5.27518 (rank : 721)
Query Neighborhood Hits	812	Target Neighborhood Hits	145	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

OST3B_MOUSE
NC score	0.001063 (rank : 1077)	θ value	3.0926 (rank : 631)
Query Neighborhood Hits	812	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

TBX6_HUMAN
NC score	0.001028 (rank : 1078)	θ value	2.36792 (rank : 594)
Query Neighborhood Hits	812	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TRI25_MOUSE
NC score	0.001021 (rank : 1079)	θ value	8.99809 (rank : 810)
Query Neighborhood Hits	812	Target Neighborhood Hits	446	Shared Neighborhood Hits	19
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

FOXGA_HUMAN
NC score	0.000909 (rank : 1080)	θ value	5.27518 (rank : 702)
Query Neighborhood Hits	812	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

FOXE3_MOUSE
NC score	0.000732 (rank : 1081)	θ value	8.99809 (rank : 785)
Query Neighborhood Hits	812	Target Neighborhood Hits	118	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QY14	Gene names	Foxe3
Domain Architecture
Description	Forkhead box protein E3.

NAL10_HUMAN
NC score	0.000533 (rank : 1082)	θ value	6.88961 (rank : 749)
Query Neighborhood Hits	812	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

HXA5_MOUSE
NC score	0.000436 (rank : 1083)	θ value	0.0736092 (rank : 353)
Query Neighborhood Hits	812	Target Neighborhood Hits	338	Shared Neighborhood Hits	19
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

RXRA_HUMAN
NC score	0.000082 (rank : 1084)	θ value	1.06291 (rank : 504)
Query Neighborhood Hits	812	Target Neighborhood Hits	223	Shared Neighborhood Hits	38
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

KIF1C_MOUSE
NC score	-0.000616 (rank : 1085)	θ value	5.27518 (rank : 707)
Query Neighborhood Hits	812	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

COT2_HUMAN
NC score	-0.000667 (rank : 1086)	θ value	8.99809 (rank : 776)
Query Neighborhood Hits	812	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	-0.000667 (rank : 1087)	θ value	8.99809 (rank : 777)
Query Neighborhood Hits	812	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

GLI2_HUMAN
NC score	-0.000823 (rank : 1088)	θ value	0.00175202 (rank : 280)
Query Neighborhood Hits	812	Target Neighborhood Hits	971	Shared Neighborhood Hits	103
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

HXB2_MOUSE
NC score	-0.001048 (rank : 1089)	θ value	4.03905 (rank : 662)
Query Neighborhood Hits	812	Target Neighborhood Hits	350	Shared Neighborhood Hits	28
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

KCNC3_MOUSE
NC score	-0.001393 (rank : 1090)	θ value	5.27518 (rank : 706)
Query Neighborhood Hits	812	Target Neighborhood Hits	173	Shared Neighborhood Hits	19
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

ACRO_HUMAN
NC score	-0.001486 (rank : 1091)	θ value	5.27518 (rank : 692)
Query Neighborhood Hits	812	Target Neighborhood Hits	291	Shared Neighborhood Hits	48
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

KCNQ1_HUMAN
NC score	-0.001886 (rank : 1092)	θ value	8.99809 (rank : 789)
Query Neighborhood Hits	812	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

ZN219_HUMAN
NC score	-0.001998 (rank : 1093)	θ value	1.81305 (rank : 570)
Query Neighborhood Hits	812	Target Neighborhood Hits	876	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

PO5F1_MOUSE
NC score	-0.002113 (rank : 1094)	θ value	4.03905 (rank : 675)
Query Neighborhood Hits	812	Target Neighborhood Hits	305	Shared Neighborhood Hits	15
SwissProt Accessions	P20263, Q63843	Gene names	Pou5f1, Oct-3, Oct-4, Otf-3, Otf3
Domain Architecture
Description	POU domain, class 5, transcription factor 1 (Octamer-binding transcription factor 3) (Oct-3) (Oct-4) (NF-A3).

ATS19_MOUSE
NC score	-0.002931 (rank : 1095)	θ value	3.0926 (rank : 604)
Query Neighborhood Hits	812	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

HXA5_HUMAN
NC score	-0.003002 (rank : 1096)	θ value	6.88961 (rank : 744)
Query Neighborhood Hits	812	Target Neighborhood Hits	336	Shared Neighborhood Hits	18
SwissProt Accessions	P20719, O43367, Q96CY6	Gene names	HOXA5, HOX1C
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1C).

PLRG1_HUMAN
NC score	-0.003590 (rank : 1097)	θ value	3.0926 (rank : 637)
Query Neighborhood Hits	812	Target Neighborhood Hits	318	Shared Neighborhood Hits	12
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

MSX3_MOUSE
NC score	-0.003651 (rank : 1098)	θ value	2.36792 (rank : 585)
Query Neighborhood Hits	812	Target Neighborhood Hits	330	Shared Neighborhood Hits	17
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

EGR4_HUMAN
NC score	-0.005751 (rank : 1099)	θ value	5.27518 (rank : 700)
Query Neighborhood Hits	812	Target Neighborhood Hits	939	Shared Neighborhood Hits	87
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

GLI1_HUMAN
NC score	-0.007341 (rank : 1100)	θ value	6.88961 (rank : 742)
Query Neighborhood Hits	812	Target Neighborhood Hits	828	Shared Neighborhood Hits	64
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HIC1_MOUSE
NC score	-0.008022 (rank : 1101)	θ value	0.62314 (rank : 458)
Query Neighborhood Hits	812	Target Neighborhood Hits	863	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

ZBT40_HUMAN
NC score	-0.009692 (rank : 1102)	θ value	1.06291 (rank : 508)
Query Neighborhood Hits	812	Target Neighborhood Hits	949	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ZN206_HUMAN
NC score	-0.009949 (rank : 1103)	θ value	0.0431538 (rank : 344)
Query Neighborhood Hits	812	Target Neighborhood Hits	853	Shared Neighborhood Hits	67
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

ZN509_MOUSE
NC score	-0.009954 (rank : 1104)	θ value	0.62314 (rank : 467)
Query Neighborhood Hits	812	Target Neighborhood Hits	990	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN628_MOUSE
NC score	-0.010565 (rank : 1105)	θ value	0.813845 (rank : 480)
Query Neighborhood Hits	812	Target Neighborhood Hits	815	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

ZXDB_HUMAN
NC score	-0.011060 (rank : 1106)	θ value	4.03905 (rank : 690)
Query Neighborhood Hits	812	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	P98169, Q9UBB3	Gene names	ZXDB
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDB.

ZN580_MOUSE
NC score	-0.011829 (rank : 1107)	θ value	8.99809 (rank : 812)
Query Neighborhood Hits	812	Target Neighborhood Hits	711	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

ZN579_HUMAN
NC score	-0.012000 (rank : 1108)	θ value	8.99809 (rank : 811)
Query Neighborhood Hits	812	Target Neighborhood Hits	726	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NAF0	Gene names	ZNF579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

PRDM4_HUMAN
NC score	-0.012388 (rank : 1109)	θ value	5.27518 (rank : 718)
Query Neighborhood Hits	812	Target Neighborhood Hits	749	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UKN5, Q9UFA6	Gene names	PRDM4, PFM1
Domain Architecture
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).