Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : YTHD1_HUMAN

For an explanation of this page, click here

YTHD1_HUMAN
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

YTHD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

YTHD1_MOUSE
θ value	0 (rank : 2)	NC score	0.988117 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	P59326, Q3T9E2	Gene names	Ythdf1
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog).

YTHD2_HUMAN
θ value	0 (rank : 3)	NC score	0.968349 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

YTHD3_HUMAN
θ value	8.17181e-102 (rank : 4)	NC score	0.947673 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTHD3_MOUSE
θ value	6.91785e-101 (rank : 5)	NC score	0.946384 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTDC1_HUMAN
θ value	5.43371e-13 (rank : 6)	NC score	0.434013 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

YTDC2_HUMAN
θ value	7.09661e-13 (rank : 7)	NC score	0.349973 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

PSL1_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.053560 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

K1802_MOUSE
θ value	0.0252991 (rank : 9)	NC score	0.044073 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	1596	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ASPP1_MOUSE
θ value	0.0431538 (rank : 10)	NC score	0.028328 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	1244	Shared Neighborhood Hits	30
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SEPT9_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.024680 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	706	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

NFM_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.010076 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	1328	Shared Neighborhood Hits	20
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SC24A_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.039277 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	394	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

MLL3_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.035554 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	1644	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TRI66_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.036314 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	491	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PCLO_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.052829 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	2046	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

JIP2_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.036972 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

BTBDC_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.042176 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MK15_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.002368 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

OGFR_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.028386 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	1582	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CAP1_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.030638 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

E2F4_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.022511 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

JIP2_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.035558 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	288	Shared Neighborhood Hits	9
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

NCOA6_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.042672 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	1076	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NIPBL_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.019903 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PCLO_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.047783 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	2275	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SELPL_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.032784 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	588	Shared Neighborhood Hits	26
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

YETS2_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.037502 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ADA12_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.010050 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	474	Shared Neighborhood Hits	11
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

GGA1_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.018413 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

MAGD4_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.018795 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	338	Shared Neighborhood Hits	19
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

CAP1_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.029188 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

GPS2_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.047012 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	459	Shared Neighborhood Hits	12
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

HGS_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.025733 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	517	Shared Neighborhood Hits	18
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

IF4G1_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.020384 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MAGD1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.018679 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

NCOA6_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.055921 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	1202	Shared Neighborhood Hits	39
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RAI1_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.024363 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ZN516_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.005993 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	1197	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CIC_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.024059 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	742	Shared Neighborhood Hits	32
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LPP_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.028128 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	775	Shared Neighborhood Hits	28
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SRRM1_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.041024 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	966	Shared Neighborhood Hits	35
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

YETS2_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.032854 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZN447_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.003472 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	899	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

NCOA3_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.013369 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

TBX4_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.006914 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

YLPM1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.034084 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	670	Shared Neighborhood Hits	32
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

AT10B_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.005895 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O94823, Q9H725	Gene names	ATP10B, ATPVB, KIAA0715
Domain Architecture
Description	Probable phospholipid-transporting ATPase VB (EC 3.6.3.1).

CSKI2_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.013479 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	812	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FMN1A_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.020103 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	423	Shared Neighborhood Hits	26
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

LIPS_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.021763 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

UBP10_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.018585 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

3BP2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.016008 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BAZ2A_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.015771 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	780	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

FA61A_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.026790 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8ND56, Q76LX7, Q96AR3, Q96K73, Q96SN5, Q9UFR3	Gene names	FAM61A, C19orf13
Domain Architecture	No domain graphic available
Description	Protein FAM61A (Putative alpha synuclein-binding protein) (AlphaSNBP).

FA61A_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.028765 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

HAIR_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.016850 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

KTN1_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.006892 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	1197	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.006025 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	1324	Shared Neighborhood Hits	13
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PI5PA_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.021371 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	749	Shared Neighborhood Hits	28
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SYNJ1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.028042 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZN687_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.007666 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	1244	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ANR25_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.007494 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	398	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CJ108_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.044564 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

IL4RA_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.016215 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

LRRF1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.016262 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	440	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

PELP1_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.022310 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	596	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PLAP_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.009678 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

SCNNB_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.010331 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

SEPT9_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.015625 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	238	Shared Neighborhood Hits	11
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SON_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.028645 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	1568	Shared Neighborhood Hits	40
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

R3HD2_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.068511 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	397	Shared Neighborhood Hits	18
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

WASIP_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.053973 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	458	Shared Neighborhood Hits	30
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.051836 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	392	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

Hits sorted by NC score

YTHD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

YTHD1_MOUSE
NC score	0.988117 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	P59326, Q3T9E2	Gene names	Ythdf1
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog).

YTHD2_HUMAN
NC score	0.968349 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

YTHD3_HUMAN
NC score	0.947673 (rank : 4)	θ value	8.17181e-102 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTHD3_MOUSE
NC score	0.946384 (rank : 5)	θ value	6.91785e-101 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTDC1_HUMAN
NC score	0.434013 (rank : 6)	θ value	5.43371e-13 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

YTDC2_HUMAN
NC score	0.349973 (rank : 7)	θ value	7.09661e-13 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

R3HD2_MOUSE
NC score	0.068511 (rank : 8)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	397	Shared Neighborhood Hits	18
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

NCOA6_HUMAN
NC score	0.055921 (rank : 9)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	1202	Shared Neighborhood Hits	39
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

WASIP_HUMAN
NC score	0.053973 (rank : 10)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	458	Shared Neighborhood Hits	30
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PSL1_HUMAN
NC score	0.053560 (rank : 11)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PCLO_HUMAN
NC score	0.052829 (rank : 12)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	2046	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

WASIP_MOUSE
NC score	0.051836 (rank : 13)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	392	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PCLO_MOUSE
NC score	0.047783 (rank : 14)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	2275	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GPS2_HUMAN
NC score	0.047012 (rank : 15)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	459	Shared Neighborhood Hits	12
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

CJ108_HUMAN
NC score	0.044564 (rank : 16)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

K1802_MOUSE
NC score	0.044073 (rank : 17)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	1596	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NCOA6_MOUSE
NC score	0.042672 (rank : 18)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	1076	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BTBDC_HUMAN
NC score	0.042176 (rank : 19)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

SRRM1_MOUSE
NC score	0.041024 (rank : 20)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	966	Shared Neighborhood Hits	35
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SC24A_MOUSE
NC score	0.039277 (rank : 21)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	394	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

YETS2_MOUSE
NC score	0.037502 (rank : 22)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

JIP2_MOUSE
NC score	0.036972 (rank : 23)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TRI66_MOUSE
NC score	0.036314 (rank : 24)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	491	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

JIP2_HUMAN
NC score	0.035558 (rank : 25)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	288	Shared Neighborhood Hits	9
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MLL3_HUMAN
NC score	0.035554 (rank : 26)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	1644	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

YLPM1_HUMAN
NC score	0.034084 (rank : 27)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	670	Shared Neighborhood Hits	32
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YETS2_HUMAN
NC score	0.032854 (rank : 28)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

SELPL_MOUSE
NC score	0.032784 (rank : 29)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	588	Shared Neighborhood Hits	26
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CAP1_HUMAN
NC score	0.030638 (rank : 30)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CAP1_MOUSE
NC score	0.029188 (rank : 31)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

FA61A_MOUSE
NC score	0.028765 (rank : 32)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

SON_HUMAN
NC score	0.028645 (rank : 33)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	1568	Shared Neighborhood Hits	40
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

OGFR_HUMAN
NC score	0.028386 (rank : 34)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1582	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ASPP1_MOUSE
NC score	0.028328 (rank : 35)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	1244	Shared Neighborhood Hits	30
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

LPP_HUMAN
NC score	0.028128 (rank : 36)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	775	Shared Neighborhood Hits	28
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SYNJ1_HUMAN
NC score	0.028042 (rank : 37)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

FA61A_HUMAN
NC score	0.026790 (rank : 38)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8ND56, Q76LX7, Q96AR3, Q96K73, Q96SN5, Q9UFR3	Gene names	FAM61A, C19orf13
Domain Architecture	No domain graphic available
Description	Protein FAM61A (Putative alpha synuclein-binding protein) (AlphaSNBP).

HGS_HUMAN
NC score	0.025733 (rank : 39)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	517	Shared Neighborhood Hits	18
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

SEPT9_HUMAN
NC score	0.024680 (rank : 40)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	706	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

RAI1_MOUSE
NC score	0.024363 (rank : 41)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CIC_MOUSE
NC score	0.024059 (rank : 42)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	742	Shared Neighborhood Hits	32
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

E2F4_HUMAN
NC score	0.022511 (rank : 43)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

PELP1_HUMAN
NC score	0.022310 (rank : 44)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	596	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

LIPS_HUMAN
NC score	0.021763 (rank : 45)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

PI5PA_HUMAN
NC score	0.021371 (rank : 46)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	749	Shared Neighborhood Hits	28
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

IF4G1_MOUSE
NC score	0.020384 (rank : 47)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

FMN1A_MOUSE
NC score	0.020103 (rank : 48)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	423	Shared Neighborhood Hits	26
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

NIPBL_HUMAN
NC score	0.019903 (rank : 49)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MAGD4_HUMAN
NC score	0.018795 (rank : 50)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	338	Shared Neighborhood Hits	19
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MAGD1_MOUSE
NC score	0.018679 (rank : 51)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

UBP10_HUMAN
NC score	0.018585 (rank : 52)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

GGA1_HUMAN
NC score	0.018413 (rank : 53)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

HAIR_MOUSE
NC score	0.016850 (rank : 54)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

LRRF1_MOUSE
NC score	0.016262 (rank : 55)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	440	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

IL4RA_MOUSE
NC score	0.016215 (rank : 56)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

3BP2_HUMAN
NC score	0.016008 (rank : 57)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BAZ2A_HUMAN
NC score	0.015771 (rank : 58)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	780	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

SEPT9_MOUSE
NC score	0.015625 (rank : 59)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	238	Shared Neighborhood Hits	11
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

CSKI2_MOUSE
NC score	0.013479 (rank : 60)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	812	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

NCOA3_MOUSE
NC score	0.013369 (rank : 61)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

SCNNB_HUMAN
NC score	0.010331 (rank : 62)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

NFM_HUMAN
NC score	0.010076 (rank : 63)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	1328	Shared Neighborhood Hits	20
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

ADA12_MOUSE
NC score	0.010050 (rank : 64)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	474	Shared Neighborhood Hits	11
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

PLAP_HUMAN
NC score	0.009678 (rank : 65)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

ZN687_HUMAN
NC score	0.007666 (rank : 66)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	1244	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ANR25_MOUSE
NC score	0.007494 (rank : 67)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	398	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

TBX4_MOUSE
NC score	0.006914 (rank : 68)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

KTN1_HUMAN
NC score	0.006892 (rank : 69)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	1197	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
NC score	0.006025 (rank : 70)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	1324	Shared Neighborhood Hits	13
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

ZN516_MOUSE
NC score	0.005993 (rank : 71)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	1197	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AT10B_HUMAN
NC score	0.005895 (rank : 72)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O94823, Q9H725	Gene names	ATP10B, ATPVB, KIAA0715
Domain Architecture
Description	Probable phospholipid-transporting ATPase VB (EC 3.6.3.1).

ZN447_HUMAN
NC score	0.003472 (rank : 73)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	899	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

MK15_HUMAN
NC score	0.002368 (rank : 74)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).