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Network neighborhood for query Sequence : EHMT2_HUMAN

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EHMT2_HUMAN
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EHMT1_HUMAN
θ value	0 (rank : 1)	NC score	0.981392 (rank : 2)
Query Neighborhood Hits	498	Target Neighborhood Hits	417	Shared Neighborhood Hits	330
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	498	Target Neighborhood Hits	498	Shared Neighborhood Hits	498
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	0 (rank : 3)	NC score	0.980498 (rank : 3)
Query Neighborhood Hits	498	Target Neighborhood Hits	750	Shared Neighborhood Hits	428
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

SUV92_MOUSE
θ value	8.32485e-38 (rank : 4)	NC score	0.416599 (rank : 255)
Query Neighborhood Hits	498	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_HUMAN
θ value	1.08726e-37 (rank : 5)	NC score	0.418616 (rank : 253)
Query Neighborhood Hits	498	Target Neighborhood Hits	54	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_HUMAN
θ value	4.13158e-37 (rank : 6)	NC score	0.422947 (rank : 250)
Query Neighborhood Hits	498	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	4.568e-36 (rank : 7)	NC score	0.419584 (rank : 252)
Query Neighborhood Hits	498	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

ANR28_MOUSE
θ value	1.6813e-30 (rank : 8)	NC score	0.853986 (rank : 9)
Query Neighborhood Hits	498	Target Neighborhood Hits	314	Shared Neighborhood Hits	302
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
θ value	9.2256e-29 (rank : 9)	NC score	0.852258 (rank : 12)
Query Neighborhood Hits	498	Target Neighborhood Hits	314	Shared Neighborhood Hits	302
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK3_HUMAN
θ value	3.87602e-27 (rank : 10)	NC score	0.831760 (rank : 44)
Query Neighborhood Hits	498	Target Neighborhood Hits	853	Shared Neighborhood Hits	340
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR44_HUMAN
θ value	5.06226e-27 (rank : 11)	NC score	0.853624 (rank : 10)
Query Neighborhood Hits	498	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANK1_HUMAN
θ value	3.28125e-26 (rank : 12)	NC score	0.839812 (rank : 32)
Query Neighborhood Hits	498	Target Neighborhood Hits	416	Shared Neighborhood Hits	310
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	3.28125e-26 (rank : 13)	NC score	0.838987 (rank : 36)
Query Neighborhood Hits	498	Target Neighborhood Hits	430	Shared Neighborhood Hits	311
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANKR6_HUMAN
θ value	4.28545e-26 (rank : 14)	NC score	0.866283 (rank : 7)
Query Neighborhood Hits	498	Target Neighborhood Hits	439	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

INVS_MOUSE
θ value	2.12685e-25 (rank : 15)	NC score	0.843834 (rank : 22)
Query Neighborhood Hits	498	Target Neighborhood Hits	609	Shared Neighborhood Hits	314
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

SETB1_HUMAN
θ value	1.05554e-24 (rank : 16)	NC score	0.356773 (rank : 272)
Query Neighborhood Hits	498	Target Neighborhood Hits	141	Shared Neighborhood Hits	32
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_MOUSE
θ value	1.05554e-24 (rank : 17)	NC score	0.361204 (rank : 271)
Query Neighborhood Hits	498	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

INVS_HUMAN
θ value	1.37858e-24 (rank : 18)	NC score	0.849051 (rank : 13)
Query Neighborhood Hits	498	Target Neighborhood Hits	455	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANR50_HUMAN
θ value	4.01107e-24 (rank : 19)	NC score	0.859834 (rank : 8)
Query Neighborhood Hits	498	Target Neighborhood Hits	361	Shared Neighborhood Hits	301
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

RIPK4_HUMAN
θ value	6.84181e-24 (rank : 20)	NC score	0.536647 (rank : 217)
Query Neighborhood Hits	498	Target Neighborhood Hits	1094	Shared Neighborhood Hits	309
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

DAPK1_MOUSE
θ value	8.93572e-24 (rank : 21)	NC score	0.387554 (rank : 262)
Query Neighborhood Hits	498	Target Neighborhood Hits	1138	Shared Neighborhood Hits	300
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ANK2_HUMAN
θ value	1.5242e-23 (rank : 22)	NC score	0.785953 (rank : 106)
Query Neighborhood Hits	498	Target Neighborhood Hits	1615	Shared Neighborhood Hits	369
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKK1_HUMAN
θ value	1.5242e-23 (rank : 23)	NC score	0.547162 (rank : 209)
Query Neighborhood Hits	498	Target Neighborhood Hits	1075	Shared Neighborhood Hits	303
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR52_MOUSE
θ value	3.39556e-23 (rank : 24)	NC score	0.843185 (rank : 24)
Query Neighborhood Hits	498	Target Neighborhood Hits	318	Shared Neighborhood Hits	304
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
θ value	4.43474e-23 (rank : 25)	NC score	0.843127 (rank : 25)
Query Neighborhood Hits	498	Target Neighborhood Hits	322	Shared Neighborhood Hits	304
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNKS1_HUMAN
θ value	9.87957e-23 (rank : 26)	NC score	0.843387 (rank : 23)
Query Neighborhood Hits	498	Target Neighborhood Hits	477	Shared Neighborhood Hits	312
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANKK1_MOUSE
θ value	1.6852e-22 (rank : 27)	NC score	0.531776 (rank : 218)
Query Neighborhood Hits	498	Target Neighborhood Hits	1072	Shared Neighborhood Hits	301
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

TNKS2_HUMAN
θ value	2.87452e-22 (rank : 28)	NC score	0.842513 (rank : 26)
Query Neighborhood Hits	498	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

DAPK1_HUMAN
θ value	1.42661e-21 (rank : 29)	NC score	0.378571 (rank : 265)
Query Neighborhood Hits	498	Target Neighborhood Hits	1130	Shared Neighborhood Hits	298
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ZDH17_HUMAN
θ value	1.86321e-21 (rank : 30)	NC score	0.759312 (rank : 130)
Query Neighborhood Hits	498	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH17_MOUSE
θ value	4.15078e-21 (rank : 31)	NC score	0.754702 (rank : 134)
Query Neighborhood Hits	498	Target Neighborhood Hits	328	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ASB10_HUMAN
θ value	5.42112e-21 (rank : 32)	NC score	0.846148 (rank : 17)
Query Neighborhood Hits	498	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

MIB2_HUMAN
θ value	1.2077e-20 (rank : 33)	NC score	0.804626 (rank : 80)
Query Neighborhood Hits	498	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB3_HUMAN
θ value	2.06002e-20 (rank : 34)	NC score	0.848955 (rank : 15)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR42_MOUSE
θ value	5.99374e-20 (rank : 35)	NC score	0.844507 (rank : 20)
Query Neighborhood Hits	498	Target Neighborhood Hits	334	Shared Neighborhood Hits	285
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR29_HUMAN
θ value	7.82807e-20 (rank : 36)	NC score	0.868957 (rank : 4)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	291
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

MIB2_MOUSE
θ value	1.02238e-19 (rank : 37)	NC score	0.802169 (rank : 87)
Query Neighborhood Hits	498	Target Neighborhood Hits	409	Shared Neighborhood Hits	284
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

NOTC4_HUMAN
θ value	2.97466e-19 (rank : 38)	NC score	0.457029 (rank : 241)
Query Neighborhood Hits	498	Target Neighborhood Hits	905	Shared Neighborhood Hits	306
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB3_MOUSE
θ value	6.62687e-19 (rank : 39)	NC score	0.846977 (rank : 16)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	294
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TNI3K_HUMAN
θ value	8.65492e-19 (rank : 40)	NC score	0.426677 (rank : 249)
Query Neighborhood Hits	498	Target Neighborhood Hits	1084	Shared Neighborhood Hits	300
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ASB10_MOUSE
θ value	1.47631e-18 (rank : 41)	NC score	0.841717 (rank : 27)
Query Neighborhood Hits	498	Target Neighborhood Hits	301	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

SETB2_HUMAN
θ value	1.47631e-18 (rank : 42)	NC score	0.367959 (rank : 270)
Query Neighborhood Hits	498	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

RAI14_MOUSE
θ value	1.92812e-18 (rank : 43)	NC score	0.596048 (rank : 196)
Query Neighborhood Hits	498	Target Neighborhood Hits	1505	Shared Neighborhood Hits	335
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

PSD10_HUMAN
θ value	4.29542e-18 (rank : 44)	NC score	0.868909 (rank : 5)
Query Neighborhood Hits	498	Target Neighborhood Hits	301	Shared Neighborhood Hits	295
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKS1_HUMAN
θ value	5.60996e-18 (rank : 45)	NC score	0.806991 (rank : 74)
Query Neighborhood Hits	498	Target Neighborhood Hits	438	Shared Neighborhood Hits	303
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

RAI14_HUMAN
θ value	5.60996e-18 (rank : 46)	NC score	0.627691 (rank : 189)
Query Neighborhood Hits	498	Target Neighborhood Hits	1367	Shared Neighborhood Hits	332
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SETD2_HUMAN
θ value	7.32683e-18 (rank : 47)	NC score	0.344780 (rank : 278)
Query Neighborhood Hits	498	Target Neighborhood Hits	412	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EZH1_MOUSE
θ value	9.56915e-18 (rank : 48)	NC score	0.342731 (rank : 282)
Query Neighborhood Hits	498	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_HUMAN
θ value	1.24977e-17 (rank : 49)	NC score	0.343227 (rank : 281)
Query Neighborhood Hits	498	Target Neighborhood Hits	121	Shared Neighborhood Hits	34
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	1.63225e-17 (rank : 50)	NC score	0.344295 (rank : 280)
Query Neighborhood Hits	498	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

NOTC4_MOUSE
θ value	1.63225e-17 (rank : 51)	NC score	0.461904 (rank : 239)
Query Neighborhood Hits	498	Target Neighborhood Hits	872	Shared Neighborhood Hits	299
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

RN5A_MOUSE
θ value	2.13179e-17 (rank : 52)	NC score	0.743945 (rank : 138)
Query Neighborhood Hits	498	Target Neighborhood Hits	899	Shared Neighborhood Hits	299
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR35_HUMAN
θ value	6.20254e-17 (rank : 53)	NC score	0.777348 (rank : 120)
Query Neighborhood Hits	498	Target Neighborhood Hits	784	Shared Neighborhood Hits	306
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANKR2_MOUSE
θ value	8.10077e-17 (rank : 54)	NC score	0.849035 (rank : 14)
Query Neighborhood Hits	498	Target Neighborhood Hits	312	Shared Neighborhood Hits	291
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

EZH2_MOUSE
θ value	8.10077e-17 (rank : 55)	NC score	0.341037 (rank : 283)
Query Neighborhood Hits	498	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

ASB2_HUMAN
θ value	1.058e-16 (rank : 56)	NC score	0.836265 (rank : 38)
Query Neighborhood Hits	498	Target Neighborhood Hits	309	Shared Neighborhood Hits	291
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CTTB2_HUMAN
θ value	1.38178e-16 (rank : 57)	NC score	0.727546 (rank : 150)
Query Neighborhood Hits	498	Target Neighborhood Hits	1061	Shared Neighborhood Hits	326
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

MIB1_MOUSE
θ value	1.38178e-16 (rank : 58)	NC score	0.805274 (rank : 79)
Query Neighborhood Hits	498	Target Neighborhood Hits	471	Shared Neighborhood Hits	297
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PSD10_MOUSE
θ value	1.38178e-16 (rank : 59)	NC score	0.866433 (rank : 6)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ASB11_MOUSE
θ value	1.80466e-16 (rank : 60)	NC score	0.805550 (rank : 78)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MIB1_HUMAN
θ value	1.80466e-16 (rank : 61)	NC score	0.806190 (rank : 76)
Query Neighborhood Hits	498	Target Neighborhood Hits	470	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

SHAN1_HUMAN
θ value	1.80466e-16 (rank : 62)	NC score	0.701648 (rank : 159)
Query Neighborhood Hits	498	Target Neighborhood Hits	1041	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

POT15_HUMAN
θ value	2.35696e-16 (rank : 63)	NC score	0.729122 (rank : 147)
Query Neighborhood Hits	498	Target Neighborhood Hits	893	Shared Neighborhood Hits	312
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NSD1_MOUSE
θ value	5.25075e-16 (rank : 64)	NC score	0.287083 (rank : 296)
Query Neighborhood Hits	498	Target Neighborhood Hits	472	Shared Neighborhood Hits	51
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

ANKR2_HUMAN
θ value	6.85773e-16 (rank : 65)	NC score	0.845656 (rank : 19)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	293
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR21_HUMAN
θ value	6.85773e-16 (rank : 66)	NC score	0.728661 (rank : 149)
Query Neighborhood Hits	498	Target Neighborhood Hits	864	Shared Neighborhood Hits	313
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASB11_HUMAN
θ value	6.85773e-16 (rank : 67)	NC score	0.804066 (rank : 83)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

NSD1_HUMAN
θ value	6.85773e-16 (rank : 68)	NC score	0.282578 (rank : 298)
Query Neighborhood Hits	498	Target Neighborhood Hits	427	Shared Neighborhood Hits	52
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ZDH13_HUMAN
θ value	8.95645e-16 (rank : 69)	NC score	0.745954 (rank : 137)
Query Neighborhood Hits	498	Target Neighborhood Hits	322	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ASB2_MOUSE
θ value	1.52774e-15 (rank : 70)	NC score	0.829067 (rank : 46)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

AN36B_HUMAN
θ value	1.99529e-15 (rank : 71)	NC score	0.805698 (rank : 77)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	286
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ASB5_HUMAN
θ value	1.99529e-15 (rank : 72)	NC score	0.803650 (rank : 84)
Query Neighborhood Hits	498	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CSKI1_MOUSE
θ value	1.99529e-15 (rank : 73)	NC score	0.778664 (rank : 118)
Query Neighborhood Hits	498	Target Neighborhood Hits	1031	Shared Neighborhood Hits	326
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

POTE8_HUMAN
θ value	1.99529e-15 (rank : 74)	NC score	0.775430 (rank : 122)
Query Neighborhood Hits	498	Target Neighborhood Hits	337	Shared Neighborhood Hits	294
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ASB13_HUMAN
θ value	2.60593e-15 (rank : 75)	NC score	0.835893 (rank : 39)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	2.60593e-15 (rank : 76)	NC score	0.836282 (rank : 37)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB5_MOUSE
θ value	2.60593e-15 (rank : 77)	NC score	0.800005 (rank : 92)
Query Neighborhood Hits	498	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ZDH13_MOUSE
θ value	2.60593e-15 (rank : 78)	NC score	0.743225 (rank : 139)
Query Neighborhood Hits	498	Target Neighborhood Hits	329	Shared Neighborhood Hits	282
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

CSKI1_HUMAN
θ value	3.40345e-15 (rank : 79)	NC score	0.778769 (rank : 117)
Query Neighborhood Hits	498	Target Neighborhood Hits	997	Shared Neighborhood Hits	321
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYPT1_HUMAN
θ value	4.44505e-15 (rank : 80)	NC score	0.791781 (rank : 100)
Query Neighborhood Hits	498	Target Neighborhood Hits	723	Shared Neighborhood Hits	333
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANKS1_MOUSE
θ value	7.58209e-15 (rank : 81)	NC score	0.790585 (rank : 102)
Query Neighborhood Hits	498	Target Neighborhood Hits	453	Shared Neighborhood Hits	300
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

NOTC2_HUMAN
θ value	7.58209e-15 (rank : 82)	NC score	0.414813 (rank : 257)
Query Neighborhood Hits	498	Target Neighborhood Hits	1113	Shared Neighborhood Hits	311
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	7.58209e-15 (rank : 83)	NC score	0.411629 (rank : 260)
Query Neighborhood Hits	498	Target Neighborhood Hits	1069	Shared Neighborhood Hits	307
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANR16_HUMAN
θ value	9.90251e-15 (rank : 84)	NC score	0.852983 (rank : 11)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	281
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

MYPT1_MOUSE
θ value	9.90251e-15 (rank : 85)	NC score	0.809401 (rank : 70)
Query Neighborhood Hits	498	Target Neighborhood Hits	539	Shared Neighborhood Hits	321
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

TNI3K_MOUSE
θ value	9.90251e-15 (rank : 86)	NC score	0.419986 (rank : 251)
Query Neighborhood Hits	498	Target Neighborhood Hits	1079	Shared Neighborhood Hits	301
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKR1_HUMAN
θ value	1.29331e-14 (rank : 87)	NC score	0.840416 (rank : 30)
Query Neighborhood Hits	498	Target Neighborhood Hits	308	Shared Neighborhood Hits	285
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

PA2G6_MOUSE
θ value	1.29331e-14 (rank : 88)	NC score	0.819865 (rank : 52)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANKR1_MOUSE
θ value	1.68911e-14 (rank : 89)	NC score	0.839765 (rank : 33)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	291
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

FANK1_MOUSE
θ value	1.68911e-14 (rank : 90)	NC score	0.844137 (rank : 21)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	285
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

FANK1_HUMAN
θ value	2.88119e-14 (rank : 91)	NC score	0.846100 (rank : 18)
Query Neighborhood Hits	498	Target Neighborhood Hits	326	Shared Neighborhood Hits	290
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

NOTC3_MOUSE
θ value	2.88119e-14 (rank : 92)	NC score	0.417976 (rank : 254)
Query Neighborhood Hits	498	Target Neighborhood Hits	975	Shared Neighborhood Hits	306
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ASB15_HUMAN
θ value	3.76295e-14 (rank : 93)	NC score	0.809192 (rank : 71)
Query Neighborhood Hits	498	Target Neighborhood Hits	305	Shared Neighborhood Hits	286
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCL3_HUMAN
θ value	3.76295e-14 (rank : 94)	NC score	0.825252 (rank : 48)
Query Neighborhood Hits	498	Target Neighborhood Hits	324	Shared Neighborhood Hits	291
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

NOTC3_HUMAN
θ value	3.76295e-14 (rank : 95)	NC score	0.415745 (rank : 256)
Query Neighborhood Hits	498	Target Neighborhood Hits	1062	Shared Neighborhood Hits	308
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RFXK_HUMAN
θ value	3.76295e-14 (rank : 96)	NC score	0.816087 (rank : 61)
Query Neighborhood Hits	498	Target Neighborhood Hits	282	Shared Neighborhood Hits	267
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

CSKI2_HUMAN
θ value	4.91457e-14 (rank : 97)	NC score	0.784098 (rank : 109)
Query Neighborhood Hits	498	Target Neighborhood Hits	747	Shared Neighborhood Hits	316
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	4.91457e-14 (rank : 98)	NC score	0.781479 (rank : 111)
Query Neighborhood Hits	498	Target Neighborhood Hits	812	Shared Neighborhood Hits	311
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB9_MOUSE
θ value	6.41864e-14 (rank : 99)	NC score	0.795928 (rank : 95)
Query Neighborhood Hits	498	Target Neighborhood Hits	257	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

AN30A_HUMAN
θ value	8.38298e-14 (rank : 100)	NC score	0.588254 (rank : 199)
Query Neighborhood Hits	498	Target Neighborhood Hits	1119	Shared Neighborhood Hits	314
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR49_MOUSE
θ value	8.38298e-14 (rank : 101)	NC score	0.839232 (rank : 35)
Query Neighborhood Hits	498	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR42_HUMAN
θ value	1.42992e-13 (rank : 102)	NC score	0.832190 (rank : 43)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB9_HUMAN
θ value	1.42992e-13 (rank : 103)	NC score	0.802565 (rank : 86)
Query Neighborhood Hits	498	Target Neighborhood Hits	267	Shared Neighborhood Hits	258
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB15_MOUSE
θ value	1.86753e-13 (rank : 104)	NC score	0.796792 (rank : 94)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANFY1_MOUSE
θ value	2.43908e-13 (rank : 105)	NC score	0.741477 (rank : 140)
Query Neighborhood Hits	498	Target Neighborhood Hits	480	Shared Neighborhood Hits	300
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR10_MOUSE
θ value	2.43908e-13 (rank : 106)	NC score	0.803583 (rank : 85)
Query Neighborhood Hits	498	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

BCL3_MOUSE
θ value	2.43908e-13 (rank : 107)	NC score	0.820336 (rank : 50)
Query Neighborhood Hits	498	Target Neighborhood Hits	388	Shared Neighborhood Hits	292
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

HRX_HUMAN
θ value	2.43908e-13 (rank : 108)	NC score	0.272659 (rank : 301)
Query Neighborhood Hits	498	Target Neighborhood Hits	825	Shared Neighborhood Hits	81
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TRPA1_HUMAN
θ value	2.43908e-13 (rank : 109)	NC score	0.816803 (rank : 60)
Query Neighborhood Hits	498	Target Neighborhood Hits	339	Shared Neighborhood Hits	298
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PP16A_MOUSE
θ value	4.16044e-13 (rank : 110)	NC score	0.807234 (rank : 73)
Query Neighborhood Hits	498	Target Neighborhood Hits	318	Shared Neighborhood Hits	287
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PP16B_MOUSE
θ value	4.16044e-13 (rank : 111)	NC score	0.794762 (rank : 98)
Query Neighborhood Hits	498	Target Neighborhood Hits	302	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR23_HUMAN
θ value	5.43371e-13 (rank : 112)	NC score	0.841238 (rank : 29)
Query Neighborhood Hits	498	Target Neighborhood Hits	291	Shared Neighborhood Hits	287
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

NOTC1_HUMAN
θ value	5.43371e-13 (rank : 113)	NC score	0.413247 (rank : 259)
Query Neighborhood Hits	498	Target Neighborhood Hits	906	Shared Neighborhood Hits	298
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANRA2_HUMAN
θ value	7.09661e-13 (rank : 114)	NC score	0.814238 (rank : 62)
Query Neighborhood Hits	498	Target Neighborhood Hits	288	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB8_HUMAN
θ value	7.09661e-13 (rank : 115)	NC score	0.839546 (rank : 34)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	287
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

MPP8_HUMAN
θ value	7.09661e-13 (rank : 116)	NC score	0.681062 (rank : 169)
Query Neighborhood Hits	498	Target Neighborhood Hits	948	Shared Neighborhood Hits	302
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

TRPA1_MOUSE
θ value	7.09661e-13 (rank : 117)	NC score	0.819404 (rank : 53)
Query Neighborhood Hits	498	Target Neighborhood Hits	343	Shared Neighborhood Hits	295
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANR10_HUMAN
θ value	9.26847e-13 (rank : 118)	NC score	0.801881 (rank : 88)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	269
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANRA2_MOUSE
θ value	9.26847e-13 (rank : 119)	NC score	0.813679 (rank : 63)
Query Neighborhood Hits	498	Target Neighborhood Hits	287	Shared Neighborhood Hits	279
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB8_MOUSE
θ value	9.26847e-13 (rank : 120)	NC score	0.840355 (rank : 31)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

SET1A_HUMAN
θ value	9.26847e-13 (rank : 121)	NC score	0.308212 (rank : 292)
Query Neighborhood Hits	498	Target Neighborhood Hits	690	Shared Neighborhood Hits	84
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ANFY1_HUMAN
θ value	1.2105e-12 (rank : 122)	NC score	0.739538 (rank : 142)
Query Neighborhood Hits	498	Target Neighborhood Hits	480	Shared Neighborhood Hits	293
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR23_MOUSE
θ value	1.2105e-12 (rank : 123)	NC score	0.841343 (rank : 28)
Query Neighborhood Hits	498	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

MYPT2_HUMAN
θ value	1.58096e-12 (rank : 124)	NC score	0.791912 (rank : 99)
Query Neighborhood Hits	498	Target Neighborhood Hits	707	Shared Neighborhood Hits	321
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANKR7_HUMAN
θ value	2.0648e-12 (rank : 125)	NC score	0.818918 (rank : 54)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	283
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ILK1_HUMAN
θ value	2.0648e-12 (rank : 126)	NC score	0.496715 (rank : 228)
Query Neighborhood Hits	498	Target Neighborhood Hits	857	Shared Neighborhood Hits	285
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	2.0648e-12 (rank : 127)	NC score	0.514331 (rank : 222)
Query Neighborhood Hits	498	Target Neighborhood Hits	848	Shared Neighborhood Hits	285
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

MLL4_HUMAN
θ value	2.0648e-12 (rank : 128)	NC score	0.259962 (rank : 303)
Query Neighborhood Hits	498	Target Neighborhood Hits	722	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PA2G6_HUMAN
θ value	2.0648e-12 (rank : 129)	NC score	0.813111 (rank : 65)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	282
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RFXK_MOUSE
θ value	2.0648e-12 (rank : 130)	NC score	0.807666 (rank : 72)
Query Neighborhood Hits	498	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ANKS3_MOUSE
θ value	2.69671e-12 (rank : 131)	NC score	0.817175 (rank : 58)
Query Neighborhood Hits	498	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB7_HUMAN
θ value	2.69671e-12 (rank : 132)	NC score	0.834862 (rank : 41)
Query Neighborhood Hits	498	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	2.69671e-12 (rank : 133)	NC score	0.834866 (rank : 40)
Query Neighborhood Hits	498	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

PP16B_HUMAN
θ value	3.52202e-12 (rank : 134)	NC score	0.794841 (rank : 97)
Query Neighborhood Hits	498	Target Neighborhood Hits	307	Shared Neighborhood Hits	284
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

RN5A_HUMAN
θ value	3.52202e-12 (rank : 135)	NC score	0.786463 (rank : 105)
Query Neighborhood Hits	498	Target Neighborhood Hits	608	Shared Neighborhood Hits	288
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ILK_MOUSE
θ value	4.59992e-12 (rank : 136)	NC score	0.494920 (rank : 229)
Query Neighborhood Hits	498	Target Neighborhood Hits	858	Shared Neighborhood Hits	285
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

A20A3_HUMAN
θ value	6.00763e-12 (rank : 137)	NC score	0.667957 (rank : 176)
Query Neighborhood Hits	498	Target Neighborhood Hits	692	Shared Neighborhood Hits	288
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	6.00763e-12 (rank : 138)	NC score	0.663177 (rank : 179)
Query Neighborhood Hits	498	Target Neighborhood Hits	710	Shared Neighborhood Hits	289
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR49_HUMAN
θ value	6.00763e-12 (rank : 139)	NC score	0.832801 (rank : 42)
Query Neighborhood Hits	498	Target Neighborhood Hits	282	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASZ1_HUMAN
θ value	6.00763e-12 (rank : 140)	NC score	0.813097 (rank : 66)
Query Neighborhood Hits	498	Target Neighborhood Hits	341	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKR5_HUMAN
θ value	7.84624e-12 (rank : 141)	NC score	0.812014 (rank : 68)
Query Neighborhood Hits	498	Target Neighborhood Hits	297	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_MOUSE
θ value	7.84624e-12 (rank : 142)	NC score	0.812477 (rank : 67)
Query Neighborhood Hits	498	Target Neighborhood Hits	298	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_HUMAN
θ value	7.84624e-12 (rank : 143)	NC score	0.813309 (rank : 64)
Query Neighborhood Hits	498	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

PP16A_HUMAN
θ value	7.84624e-12 (rank : 144)	NC score	0.800444 (rank : 90)
Query Neighborhood Hits	498	Target Neighborhood Hits	340	Shared Neighborhood Hits	281
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

A20A1_HUMAN
θ value	1.33837e-11 (rank : 145)	NC score	0.665788 (rank : 178)
Query Neighborhood Hits	498	Target Neighborhood Hits	698	Shared Neighborhood Hits	285
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	1.33837e-11 (rank : 146)	NC score	0.667150 (rank : 177)
Query Neighborhood Hits	498	Target Neighborhood Hits	716	Shared Neighborhood Hits	291
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANR19_HUMAN
θ value	1.74796e-11 (rank : 147)	NC score	0.769666 (rank : 129)
Query Neighborhood Hits	498	Target Neighborhood Hits	276	Shared Neighborhood Hits	273
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ASZ1_MOUSE
θ value	1.74796e-11 (rank : 148)	NC score	0.817106 (rank : 59)
Query Neighborhood Hits	498	Target Neighborhood Hits	319	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MLL3_HUMAN
θ value	1.74796e-11 (rank : 149)	NC score	0.205839 (rank : 314)
Query Neighborhood Hits	498	Target Neighborhood Hits	1644	Shared Neighborhood Hits	118
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CENB2_HUMAN
θ value	2.28291e-11 (rank : 150)	NC score	0.537176 (rank : 216)
Query Neighborhood Hits	498	Target Neighborhood Hits	425	Shared Neighborhood Hits	258
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ANR18_HUMAN
θ value	3.89403e-11 (rank : 151)	NC score	0.614476 (rank : 192)
Query Neighborhood Hits	498	Target Neighborhood Hits	1106	Shared Neighborhood Hits	300
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

MLL2_HUMAN
θ value	3.89403e-11 (rank : 152)	NC score	0.207475 (rank : 313)
Query Neighborhood Hits	498	Target Neighborhood Hits	1788	Shared Neighborhood Hits	99
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ASB14_MOUSE
θ value	5.08577e-11 (rank : 153)	NC score	0.795521 (rank : 96)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

BARD1_HUMAN
θ value	5.08577e-11 (rank : 154)	NC score	0.773930 (rank : 125)
Query Neighborhood Hits	498	Target Neighborhood Hits	427	Shared Neighborhood Hits	292
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MLL3_MOUSE
θ value	5.08577e-11 (rank : 155)	NC score	0.211364 (rank : 312)
Query Neighborhood Hits	498	Target Neighborhood Hits	1399	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ANR12_HUMAN
θ value	6.64225e-11 (rank : 156)	NC score	0.700527 (rank : 160)
Query Neighborhood Hits	498	Target Neighborhood Hits	1081	Shared Neighborhood Hits	332
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

USH1G_HUMAN
θ value	6.64225e-11 (rank : 157)	NC score	0.757512 (rank : 133)
Query Neighborhood Hits	498	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	6.64225e-11 (rank : 158)	NC score	0.757678 (rank : 132)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ASB4_HUMAN
θ value	8.67504e-11 (rank : 159)	NC score	0.787943 (rank : 103)
Query Neighborhood Hits	498	Target Neighborhood Hits	264	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
θ value	1.133e-10 (rank : 160)	NC score	0.786963 (rank : 104)
Query Neighborhood Hits	498	Target Neighborhood Hits	265	Shared Neighborhood Hits	260
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

BARD1_MOUSE
θ value	1.133e-10 (rank : 161)	NC score	0.772983 (rank : 127)
Query Neighborhood Hits	498	Target Neighborhood Hits	411	Shared Neighborhood Hits	283
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

AN36A_HUMAN
θ value	1.47974e-10 (rank : 162)	NC score	0.773738 (rank : 126)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

CLPB_MOUSE
θ value	1.47974e-10 (rank : 163)	NC score	0.694741 (rank : 163)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	254
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

OSBL1_MOUSE
θ value	1.9326e-10 (rank : 164)	NC score	0.635114 (rank : 187)
Query Neighborhood Hits	498	Target Neighborhood Hits	336	Shared Neighborhood Hits	285
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

UACA_HUMAN
θ value	1.9326e-10 (rank : 165)	NC score	0.494739 (rank : 230)
Query Neighborhood Hits	498	Target Neighborhood Hits	1622	Shared Neighborhood Hits	335
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ASB16_MOUSE
θ value	2.52405e-10 (rank : 166)	NC score	0.811046 (rank : 69)
Query Neighborhood Hits	498	Target Neighborhood Hits	306	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CDN2C_MOUSE
θ value	3.29651e-10 (rank : 167)	NC score	0.806344 (rank : 75)
Query Neighborhood Hits	498	Target Neighborhood Hits	270	Shared Neighborhood Hits	270
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

OSBL1_HUMAN
θ value	3.29651e-10 (rank : 168)	NC score	0.646123 (rank : 184)
Query Neighborhood Hits	498	Target Neighborhood Hits	368	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ASB16_HUMAN
θ value	5.62301e-10 (rank : 169)	NC score	0.804188 (rank : 82)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	274
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

GABP2_HUMAN
θ value	9.59137e-10 (rank : 170)	NC score	0.818563 (rank : 55)
Query Neighborhood Hits	498	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	9.59137e-10 (rank : 171)	NC score	0.820621 (rank : 49)
Query Neighborhood Hits	498	Target Neighborhood Hits	429	Shared Neighborhood Hits	288
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

NFKB2_HUMAN
θ value	9.59137e-10 (rank : 172)	NC score	0.696714 (rank : 161)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	281
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANS4B_HUMAN
θ value	1.25267e-09 (rank : 173)	NC score	0.752926 (rank : 135)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CDN2C_HUMAN
θ value	1.25267e-09 (rank : 174)	NC score	0.804509 (rank : 81)
Query Neighborhood Hits	498	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR11_HUMAN
θ value	1.63604e-09 (rank : 175)	NC score	0.729406 (rank : 146)
Query Neighborhood Hits	498	Target Neighborhood Hits	1289	Shared Neighborhood Hits	349
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

UACA_MOUSE
θ value	1.63604e-09 (rank : 176)	NC score	0.469233 (rank : 237)
Query Neighborhood Hits	498	Target Neighborhood Hits	1620	Shared Neighborhood Hits	332
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANR26_MOUSE
θ value	2.13673e-09 (rank : 177)	NC score	0.459648 (rank : 240)
Query Neighborhood Hits	498	Target Neighborhood Hits	1554	Shared Neighborhood Hits	328
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NFKB1_MOUSE
θ value	2.13673e-09 (rank : 178)	NC score	0.694097 (rank : 164)
Query Neighborhood Hits	498	Target Neighborhood Hits	300	Shared Neighborhood Hits	272
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NOTC1_MOUSE
θ value	2.13673e-09 (rank : 179)	NC score	0.353341 (rank : 276)
Query Neighborhood Hits	498	Target Neighborhood Hits	916	Shared Neighborhood Hits	278
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKY2_HUMAN
θ value	2.79066e-09 (rank : 180)	NC score	0.747005 (rank : 136)
Query Neighborhood Hits	498	Target Neighborhood Hits	306	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANKY2_MOUSE
θ value	2.79066e-09 (rank : 181)	NC score	0.720020 (rank : 151)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	265
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR22_HUMAN
θ value	2.79066e-09 (rank : 182)	NC score	0.799125 (rank : 93)
Query Neighborhood Hits	498	Target Neighborhood Hits	243	Shared Neighborhood Hits	243
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR39_HUMAN
θ value	2.79066e-09 (rank : 183)	NC score	0.831086 (rank : 45)
Query Neighborhood Hits	498	Target Neighborhood Hits	285	Shared Neighborhood Hits	283
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
θ value	2.79066e-09 (rank : 184)	NC score	0.827922 (rank : 47)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

SETD8_MOUSE
θ value	2.79066e-09 (rank : 185)	NC score	0.296885 (rank : 293)
Query Neighborhood Hits	498	Target Neighborhood Hits	131	Shared Neighborhood Hits	30
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

ANKS6_HUMAN
θ value	3.64472e-09 (rank : 186)	NC score	0.800389 (rank : 91)
Query Neighborhood Hits	498	Target Neighborhood Hits	411	Shared Neighborhood Hits	306
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR26_HUMAN
θ value	3.64472e-09 (rank : 187)	NC score	0.441889 (rank : 247)
Query Neighborhood Hits	498	Target Neighborhood Hits	1614	Shared Neighborhood Hits	336
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB12_MOUSE
θ value	3.64472e-09 (rank : 188)	NC score	0.776676 (rank : 121)
Query Neighborhood Hits	498	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

NFKB2_MOUSE
θ value	3.64472e-09 (rank : 189)	NC score	0.679296 (rank : 170)
Query Neighborhood Hits	498	Target Neighborhood Hits	326	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ACBD6_MOUSE
θ value	4.76016e-09 (rank : 190)	NC score	0.784434 (rank : 108)
Query Neighborhood Hits	498	Target Neighborhood Hits	305	Shared Neighborhood Hits	291
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR47_HUMAN
θ value	6.21693e-09 (rank : 191)	NC score	0.691685 (rank : 166)
Query Neighborhood Hits	498	Target Neighborhood Hits	369	Shared Neighborhood Hits	263
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

GABP3_MOUSE
θ value	6.21693e-09 (rank : 192)	NC score	0.817296 (rank : 57)
Query Neighborhood Hits	498	Target Neighborhood Hits	330	Shared Neighborhood Hits	278
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

OSTF1_HUMAN
θ value	6.21693e-09 (rank : 193)	NC score	0.621884 (rank : 191)
Query Neighborhood Hits	498	Target Neighborhood Hits	466	Shared Neighborhood Hits	254
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANKS6_MOUSE
θ value	8.11959e-09 (rank : 194)	NC score	0.800730 (rank : 89)
Query Neighborhood Hits	498	Target Neighborhood Hits	435	Shared Neighborhood Hits	302
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ACBD6_HUMAN
θ value	1.38499e-08 (rank : 195)	NC score	0.780315 (rank : 114)
Query Neighborhood Hits	498	Target Neighborhood Hits	304	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASPP2_HUMAN
θ value	1.38499e-08 (rank : 196)	NC score	0.557716 (rank : 207)
Query Neighborhood Hits	498	Target Neighborhood Hits	1156	Shared Neighborhood Hits	303
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

NFKB1_HUMAN
θ value	1.38499e-08 (rank : 197)	NC score	0.693896 (rank : 165)
Query Neighborhood Hits	498	Target Neighborhood Hits	306	Shared Neighborhood Hits	279
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ASB1_HUMAN
θ value	1.80886e-08 (rank : 198)	NC score	0.782379 (rank : 110)
Query Neighborhood Hits	498	Target Neighborhood Hits	291	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

IKBE_MOUSE
θ value	1.80886e-08 (rank : 199)	NC score	0.778807 (rank : 116)
Query Neighborhood Hits	498	Target Neighborhood Hits	308	Shared Neighborhood Hits	282
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR15_HUMAN
θ value	2.36244e-08 (rank : 200)	NC score	0.712859 (rank : 153)
Query Neighborhood Hits	498	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANS4B_MOUSE
θ value	2.36244e-08 (rank : 201)	NC score	0.741246 (rank : 141)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB12_HUMAN
θ value	2.36244e-08 (rank : 202)	NC score	0.779373 (rank : 115)
Query Neighborhood Hits	498	Target Neighborhood Hits	263	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

MTPN_HUMAN
θ value	2.36244e-08 (rank : 203)	NC score	0.818241 (rank : 56)
Query Neighborhood Hits	498	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	2.36244e-08 (rank : 204)	NC score	0.820298 (rank : 51)
Query Neighborhood Hits	498	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

OSTF1_MOUSE
θ value	2.36244e-08 (rank : 205)	NC score	0.637119 (rank : 186)
Query Neighborhood Hits	498	Target Neighborhood Hits	467	Shared Neighborhood Hits	256
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

IKBA_HUMAN
θ value	3.08544e-08 (rank : 206)	NC score	0.784886 (rank : 107)
Query Neighborhood Hits	498	Target Neighborhood Hits	280	Shared Neighborhood Hits	276
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

SETD8_HUMAN
θ value	3.08544e-08 (rank : 207)	NC score	0.293914 (rank : 294)
Query Neighborhood Hits	498	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

ASB1_MOUSE
θ value	5.26297e-08 (rank : 208)	NC score	0.778467 (rank : 119)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENB1_HUMAN
θ value	8.97725e-08 (rank : 209)	NC score	0.542177 (rank : 212)
Query Neighborhood Hits	498	Target Neighborhood Hits	383	Shared Neighborhood Hits	257
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

IKBE_HUMAN
θ value	1.99992e-07 (rank : 210)	NC score	0.758370 (rank : 131)
Query Neighborhood Hits	498	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

NUD12_MOUSE
θ value	1.99992e-07 (rank : 211)	NC score	0.577660 (rank : 203)
Query Neighborhood Hits	498	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CENB5_HUMAN
θ value	2.61198e-07 (rank : 212)	NC score	0.542897 (rank : 211)
Query Neighborhood Hits	498	Target Neighborhood Hits	395	Shared Neighborhood Hits	264
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CLPB_HUMAN
θ value	2.61198e-07 (rank : 213)	NC score	0.606483 (rank : 193)
Query Neighborhood Hits	498	Target Neighborhood Hits	265	Shared Neighborhood Hits	241
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR47_MOUSE
θ value	5.81887e-07 (rank : 214)	NC score	0.704545 (rank : 157)
Query Neighborhood Hits	498	Target Neighborhood Hits	350	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

IKBA_MOUSE
θ value	5.81887e-07 (rank : 215)	NC score	0.772319 (rank : 128)
Query Neighborhood Hits	498	Target Neighborhood Hits	283	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IASPP_MOUSE
θ value	7.59969e-07 (rank : 216)	NC score	0.502162 (rank : 225)
Query Neighborhood Hits	498	Target Neighborhood Hits	1024	Shared Neighborhood Hits	283
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

POT14_HUMAN
θ value	7.59969e-07 (rank : 217)	NC score	0.705057 (rank : 156)
Query Neighborhood Hits	498	Target Neighborhood Hits	403	Shared Neighborhood Hits	284
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

POT22_HUMAN
θ value	9.92553e-07 (rank : 218)	NC score	0.670314 (rank : 174)
Query Neighborhood Hits	498	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

SNCAP_HUMAN
θ value	9.92553e-07 (rank : 219)	NC score	0.695807 (rank : 162)
Query Neighborhood Hits	498	Target Neighborhood Hits	313	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ABTB2_HUMAN
θ value	1.29631e-06 (rank : 220)	NC score	0.572543 (rank : 204)
Query Neighborhood Hits	498	Target Neighborhood Hits	391	Shared Neighborhood Hits	239
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR38_MOUSE
θ value	1.29631e-06 (rank : 221)	NC score	0.624168 (rank : 190)
Query Neighborhood Hits	498	Target Neighborhood Hits	512	Shared Neighborhood Hits	248
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

IASPP_HUMAN
θ value	1.29631e-06 (rank : 222)	NC score	0.550619 (rank : 208)
Query Neighborhood Hits	498	Target Neighborhood Hits	688	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANR38_HUMAN
θ value	1.69304e-06 (rank : 223)	NC score	0.644824 (rank : 185)
Query Neighborhood Hits	498	Target Neighborhood Hits	443	Shared Neighborhood Hits	245
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR32_MOUSE
θ value	2.88788e-06 (rank : 224)	NC score	0.728990 (rank : 148)
Query Neighborhood Hits	498	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR25_MOUSE
θ value	3.77169e-06 (rank : 225)	NC score	0.648240 (rank : 183)
Query Neighborhood Hits	498	Target Neighborhood Hits	398	Shared Neighborhood Hits	266
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR32_HUMAN
θ value	3.77169e-06 (rank : 226)	NC score	0.736120 (rank : 143)
Query Neighborhood Hits	498	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

KRIT1_MOUSE
θ value	3.77169e-06 (rank : 227)	NC score	0.662208 (rank : 180)
Query Neighborhood Hits	498	Target Neighborhood Hits	258	Shared Neighborhood Hits	231
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ABTB2_MOUSE
θ value	4.92598e-06 (rank : 228)	NC score	0.560157 (rank : 206)
Query Neighborhood Hits	498	Target Neighborhood Hits	414	Shared Neighborhood Hits	240
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP1_HUMAN
θ value	6.43352e-06 (rank : 229)	NC score	0.538584 (rank : 214)
Query Neighborhood Hits	498	Target Neighborhood Hits	956	Shared Neighborhood Hits	294
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	6.43352e-06 (rank : 230)	NC score	0.526208 (rank : 220)
Query Neighborhood Hits	498	Target Neighborhood Hits	1244	Shared Neighborhood Hits	302
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CDN2D_HUMAN
θ value	6.43352e-06 (rank : 231)	NC score	0.791720 (rank : 101)
Query Neighborhood Hits	498	Target Neighborhood Hits	268	Shared Neighborhood Hits	267
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR46_HUMAN
θ value	1.09739e-05 (rank : 232)	NC score	0.781282 (rank : 112)
Query Neighborhood Hits	498	Target Neighborhood Hits	281	Shared Neighborhood Hits	274
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

BCOR_MOUSE
θ value	1.09739e-05 (rank : 233)	NC score	0.683063 (rank : 168)
Query Neighborhood Hits	498	Target Neighborhood Hits	521	Shared Neighborhood Hits	293
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

NUD12_HUMAN
θ value	1.09739e-05 (rank : 234)	NC score	0.544063 (rank : 210)
Query Neighborhood Hits	498	Target Neighborhood Hits	222	Shared Neighborhood Hits	203
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV6_MOUSE
θ value	1.09739e-05 (rank : 235)	NC score	0.537629 (rank : 215)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	257
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR25_HUMAN
θ value	1.43324e-05 (rank : 236)	NC score	0.658341 (rank : 181)
Query Neighborhood Hits	498	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ASB6_HUMAN
θ value	1.87187e-05 (rank : 237)	NC score	0.712979 (rank : 152)
Query Neighborhood Hits	498	Target Neighborhood Hits	256	Shared Neighborhood Hits	247
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
θ value	1.87187e-05 (rank : 238)	NC score	0.709735 (rank : 154)
Query Neighborhood Hits	498	Target Neighborhood Hits	264	Shared Neighborhood Hits	245
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLR59_HUMAN
θ value	1.87187e-05 (rank : 239)	NC score	0.317042 (rank : 287)
Query Neighborhood Hits	498	Target Neighborhood Hits	163	Shared Neighborhood Hits	142
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

BCOR_HUMAN
θ value	2.44474e-05 (rank : 240)	NC score	0.674395 (rank : 172)
Query Neighborhood Hits	498	Target Neighborhood Hits	609	Shared Neighborhood Hits	289
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

DGKZ_HUMAN
θ value	2.44474e-05 (rank : 241)	NC score	0.373006 (rank : 267)
Query Neighborhood Hits	498	Target Neighborhood Hits	551	Shared Neighborhood Hits	219
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_MOUSE
θ value	2.44474e-05 (rank : 242)	NC score	0.355096 (rank : 274)
Query Neighborhood Hits	498	Target Neighborhood Hits	542	Shared Neighborhood Hits	206
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

KRIT1_HUMAN
θ value	2.44474e-05 (rank : 243)	NC score	0.651485 (rank : 182)
Query Neighborhood Hits	498	Target Neighborhood Hits	258	Shared Neighborhood Hits	227
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR46_MOUSE
θ value	4.1701e-05 (rank : 244)	NC score	0.773946 (rank : 124)
Query Neighborhood Hits	498	Target Neighborhood Hits	274	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

HECD1_HUMAN
θ value	4.1701e-05 (rank : 245)	NC score	0.580843 (rank : 202)
Query Neighborhood Hits	498	Target Neighborhood Hits	371	Shared Neighborhood Hits	272
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR33_MOUSE
θ value	5.44631e-05 (rank : 246)	NC score	0.676734 (rank : 171)
Query Neighborhood Hits	498	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

TRPV5_HUMAN
θ value	5.44631e-05 (rank : 247)	NC score	0.456337 (rank : 242)
Query Neighborhood Hits	498	Target Neighborhood Hits	261	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13A_HUMAN
θ value	7.1131e-05 (rank : 248)	NC score	0.439423 (rank : 248)
Query Neighborhood Hits	498	Target Neighborhood Hits	243	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANR43_HUMAN
θ value	7.1131e-05 (rank : 249)	NC score	0.598529 (rank : 194)
Query Neighborhood Hits	498	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
θ value	7.1131e-05 (rank : 250)	NC score	0.594172 (rank : 198)
Query Neighborhood Hits	498	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ASB14_HUMAN
θ value	7.1131e-05 (rank : 251)	NC score	0.539117 (rank : 213)
Query Neighborhood Hits	498	Target Neighborhood Hits	187	Shared Neighborhood Hits	174
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CD2A1_MOUSE
θ value	7.1131e-05 (rank : 252)	NC score	0.673815 (rank : 173)
Query Neighborhood Hits	498	Target Neighborhood Hits	206	Shared Neighborhood Hits	202
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

RSNL2_HUMAN
θ value	0.000121331 (rank : 253)	NC score	0.256036 (rank : 304)
Query Neighborhood Hits	498	Target Neighborhood Hits	136	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CT012_MOUSE
θ value	0.000158464 (rank : 254)	NC score	0.454439 (rank : 243)
Query Neighborhood Hits	498	Target Neighborhood Hits	229	Shared Neighborhood Hits	180
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

ANR33_HUMAN
θ value	0.00020696 (rank : 255)	NC score	0.670096 (rank : 175)
Query Neighborhood Hits	498	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CDN2B_MOUSE
θ value	0.00020696 (rank : 256)	NC score	0.635072 (rank : 188)
Query Neighborhood Hits	498	Target Neighborhood Hits	201	Shared Neighborhood Hits	198
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

TRPV5_MOUSE
θ value	0.00020696 (rank : 257)	NC score	0.482999 (rank : 234)
Query Neighborhood Hits	498	Target Neighborhood Hits	278	Shared Neighborhood Hits	250
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR40_HUMAN
θ value	0.000270298 (rank : 258)	NC score	0.584226 (rank : 200)
Query Neighborhood Hits	498	Target Neighborhood Hits	224	Shared Neighborhood Hits	202
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	0.000270298 (rank : 259)	NC score	0.583223 (rank : 201)
Query Neighborhood Hits	498	Target Neighborhood Hits	228	Shared Neighborhood Hits	206
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CDN2D_MOUSE
θ value	0.000270298 (rank : 260)	NC score	0.780813 (rank : 113)
Query Neighborhood Hits	498	Target Neighborhood Hits	267	Shared Neighborhood Hits	265
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

IKBB_HUMAN
θ value	0.000270298 (rank : 261)	NC score	0.732644 (rank : 145)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

TRPV6_HUMAN
θ value	0.000270298 (rank : 262)	NC score	0.453530 (rank : 244)
Query Neighborhood Hits	498	Target Neighborhood Hits	262	Shared Neighborhood Hits	229
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ANR37_MOUSE
θ value	0.000461057 (rank : 263)	NC score	0.686889 (rank : 167)
Query Neighborhood Hits	498	Target Neighborhood Hits	237	Shared Neighborhood Hits	237
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

IKBB_MOUSE
θ value	0.000461057 (rank : 264)	NC score	0.733081 (rank : 144)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

RSNL2_MOUSE
θ value	0.000461057 (rank : 265)	NC score	0.226171 (rank : 309)
Query Neighborhood Hits	498	Target Neighborhood Hits	129	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CDN2B_HUMAN
θ value	0.000602161 (rank : 266)	NC score	0.597481 (rank : 195)
Query Neighborhood Hits	498	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CENG1_HUMAN
θ value	0.000602161 (rank : 267)	NC score	0.353344 (rank : 275)
Query Neighborhood Hits	498	Target Neighborhood Hits	544	Shared Neighborhood Hits	247
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DDFL1_MOUSE
θ value	0.000602161 (rank : 268)	NC score	0.449812 (rank : 245)
Query Neighborhood Hits	498	Target Neighborhood Hits	324	Shared Neighborhood Hits	250
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GIT2_MOUSE
θ value	0.000602161 (rank : 269)	NC score	0.499537 (rank : 226)
Query Neighborhood Hits	498	Target Neighborhood Hits	323	Shared Neighborhood Hits	254
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GLSL_HUMAN
θ value	0.000602161 (rank : 270)	NC score	0.498115 (rank : 227)
Query Neighborhood Hits	498	Target Neighborhood Hits	211	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANR37_HUMAN
θ value	0.000786445 (rank : 271)	NC score	0.705087 (rank : 155)
Query Neighborhood Hits	498	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

CENG1_MOUSE
θ value	0.000786445 (rank : 272)	NC score	0.356354 (rank : 273)
Query Neighborhood Hits	498	Target Neighborhood Hits	531	Shared Neighborhood Hits	249
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

GIT1_HUMAN
θ value	0.000786445 (rank : 273)	NC score	0.483057 (rank : 233)
Query Neighborhood Hits	498	Target Neighborhood Hits	336	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.000786445 (rank : 274)	NC score	0.483722 (rank : 232)
Query Neighborhood Hits	498	Target Neighborhood Hits	341	Shared Neighborhood Hits	250
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

TCAL5_HUMAN
θ value	0.000786445 (rank : 275)	NC score	0.044609 (rank : 391)
Query Neighborhood Hits	498	Target Neighborhood Hits	806	Shared Neighborhood Hits	63
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TEX14_MOUSE
θ value	0.000786445 (rank : 276)	NC score	0.376671 (rank : 266)
Query Neighborhood Hits	498	Target Neighborhood Hits	1333	Shared Neighborhood Hits	281
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

GIT2_HUMAN
θ value	0.00134147 (rank : 277)	NC score	0.462475 (rank : 238)
Query Neighborhood Hits	498	Target Neighborhood Hits	381	Shared Neighborhood Hits	250
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ABTB1_MOUSE
θ value	0.00175202 (rank : 278)	NC score	0.314924 (rank : 291)
Query Neighborhood Hits	498	Target Neighborhood Hits	349	Shared Neighborhood Hits	178
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

CD2A1_HUMAN
θ value	0.00175202 (rank : 279)	NC score	0.596020 (rank : 197)
Query Neighborhood Hits	498	Target Neighborhood Hits	196	Shared Neighborhood Hits	192
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

AN13A_MOUSE
θ value	0.00228821 (rank : 280)	NC score	0.411289 (rank : 261)
Query Neighborhood Hits	498	Target Neighborhood Hits	226	Shared Neighborhood Hits	217
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

DGKI_HUMAN
θ value	0.00390308 (rank : 281)	NC score	0.337923 (rank : 284)
Query Neighborhood Hits	498	Target Neighborhood Hits	609	Shared Neighborhood Hits	219
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

AN13B_HUMAN
θ value	0.00509761 (rank : 282)	NC score	0.504640 (rank : 224)
Query Neighborhood Hits	498	Target Neighborhood Hits	265	Shared Neighborhood Hits	254
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.00509761 (rank : 283)	NC score	0.505412 (rank : 223)
Query Neighborhood Hits	498	Target Neighborhood Hits	276	Shared Neighborhood Hits	256
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CENG2_HUMAN
θ value	0.00509761 (rank : 284)	NC score	0.347788 (rank : 277)
Query Neighborhood Hits	498	Target Neighborhood Hits	471	Shared Neighborhood Hits	255
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
θ value	0.00869519 (rank : 285)	NC score	0.344435 (rank : 279)
Query Neighborhood Hits	498	Target Neighborhood Hits	463	Shared Neighborhood Hits	250
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CT012_HUMAN
θ value	0.00869519 (rank : 286)	NC score	0.414452 (rank : 258)
Query Neighborhood Hits	498	Target Neighborhood Hits	205	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CT086_HUMAN
θ value	0.00869519 (rank : 287)	NC score	0.774808 (rank : 123)
Query Neighborhood Hits	498	Target Neighborhood Hits	277	Shared Neighborhood Hits	271
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

DDEF2_HUMAN
θ value	0.00869519 (rank : 288)	NC score	0.382013 (rank : 263)
Query Neighborhood Hits	498	Target Neighborhood Hits	599	Shared Neighborhood Hits	242
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.00869519 (rank : 289)	NC score	0.379019 (rank : 264)
Query Neighborhood Hits	498	Target Neighborhood Hits	625	Shared Neighborhood Hits	247
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ABTB1_HUMAN
θ value	0.0113563 (rank : 290)	NC score	0.273595 (rank : 300)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

CENG3_HUMAN
θ value	0.0113563 (rank : 291)	NC score	0.315993 (rank : 290)
Query Neighborhood Hits	498	Target Neighborhood Hits	455	Shared Neighborhood Hits	230
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.0113563 (rank : 292)	NC score	0.316211 (rank : 289)
Query Neighborhood Hits	498	Target Neighborhood Hits	467	Shared Neighborhood Hits	232
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

NASP_HUMAN
θ value	0.0193708 (rank : 293)	NC score	0.067890 (rank : 335)
Query Neighborhood Hits	498	Target Neighborhood Hits	709	Shared Neighborhood Hits	72
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

GLSL_MOUSE
θ value	0.0252991 (rank : 294)	NC score	0.482480 (rank : 235)
Query Neighborhood Hits	498	Target Neighborhood Hits	212	Shared Neighborhood Hits	203
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TRPC6_HUMAN
θ value	0.0252991 (rank : 295)	NC score	0.123058 (rank : 321)
Query Neighborhood Hits	498	Target Neighborhood Hits	171	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

CLSPN_MOUSE
θ value	0.0330416 (rank : 296)	NC score	0.044606 (rank : 392)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

XRCC4_HUMAN
θ value	0.0330416 (rank : 297)	NC score	0.059186 (rank : 341)
Query Neighborhood Hits	498	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

ZBT24_HUMAN
θ value	0.0330416 (rank : 298)	NC score	-0.010749 (rank : 542)
Query Neighborhood Hits	498	Target Neighborhood Hits	870	Shared Neighborhood Hits	21
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).

ANKY1_HUMAN
θ value	0.0431538 (rank : 299)	NC score	0.521412 (rank : 221)
Query Neighborhood Hits	498	Target Neighborhood Hits	248	Shared Neighborhood Hits	207
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

DDFL1_HUMAN
θ value	0.0431538 (rank : 300)	NC score	0.368047 (rank : 269)
Query Neighborhood Hits	498	Target Neighborhood Hits	353	Shared Neighborhood Hits	234
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

EMIL3_HUMAN
θ value	0.0431538 (rank : 301)	NC score	0.037534 (rank : 406)
Query Neighborhood Hits	498	Target Neighborhood Hits	249	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

VPS72_HUMAN
θ value	0.0431538 (rank : 302)	NC score	0.052513 (rank : 370)
Query Neighborhood Hits	498	Target Neighborhood Hits	274	Shared Neighborhood Hits	25
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ADDB_MOUSE
θ value	0.0563607 (rank : 303)	NC score	0.033972 (rank : 424)
Query Neighborhood Hits	498	Target Neighborhood Hits	574	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AN13C_HUMAN
θ value	0.0563607 (rank : 304)	NC score	0.493329 (rank : 231)
Query Neighborhood Hits	498	Target Neighborhood Hits	241	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

LARP1_HUMAN
θ value	0.0563607 (rank : 305)	NC score	0.042804 (rank : 395)
Query Neighborhood Hits	498	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

TRPC3_HUMAN
θ value	0.0563607 (rank : 306)	NC score	0.102774 (rank : 325)
Query Neighborhood Hits	498	Target Neighborhood Hits	137	Shared Neighborhood Hits	84
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC4_HUMAN
θ value	0.0563607 (rank : 307)	NC score	0.080270 (rank : 330)
Query Neighborhood Hits	498	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0.0563607 (rank : 308)	NC score	0.080269 (rank : 331)
Query Neighborhood Hits	498	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

VPS72_MOUSE
θ value	0.0563607 (rank : 309)	NC score	0.053648 (rank : 360)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	26
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ANKZ1_MOUSE
θ value	0.0736092 (rank : 310)	NC score	0.316215 (rank : 288)
Query Neighborhood Hits	498	Target Neighborhood Hits	208	Shared Neighborhood Hits	154
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

EST1A_HUMAN
θ value	0.0736092 (rank : 311)	NC score	0.040935 (rank : 401)
Query Neighborhood Hits	498	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

PEPL_MOUSE
θ value	0.0736092 (rank : 312)	NC score	0.034146 (rank : 422)
Query Neighborhood Hits	498	Target Neighborhood Hits	1105	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

AKA12_HUMAN
θ value	0.0961366 (rank : 313)	NC score	0.059147 (rank : 342)
Query Neighborhood Hits	498	Target Neighborhood Hits	825	Shared Neighborhood Hits	76
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AN13C_MOUSE
θ value	0.125558 (rank : 314)	NC score	0.481841 (rank : 236)
Query Neighborhood Hits	498	Target Neighborhood Hits	242	Shared Neighborhood Hits	234
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

IKBL_MOUSE
θ value	0.125558 (rank : 315)	NC score	0.322014 (rank : 286)
Query Neighborhood Hits	498	Target Neighborhood Hits	196	Shared Neighborhood Hits	143
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LEO1_MOUSE
θ value	0.125558 (rank : 316)	NC score	0.045539 (rank : 389)
Query Neighborhood Hits	498	Target Neighborhood Hits	946	Shared Neighborhood Hits	77
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TEX14_HUMAN
θ value	0.125558 (rank : 317)	NC score	0.368562 (rank : 268)
Query Neighborhood Hits	498	Target Neighborhood Hits	1103	Shared Neighborhood Hits	266
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ZN385_HUMAN
θ value	0.125558 (rank : 318)	NC score	0.027885 (rank : 436)
Query Neighborhood Hits	498	Target Neighborhood Hits	614	Shared Neighborhood Hits	31
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

EST1A_MOUSE
θ value	0.163984 (rank : 319)	NC score	0.035954 (rank : 414)
Query Neighborhood Hits	498	Target Neighborhood Hits	138	Shared Neighborhood Hits	16
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

TRPC6_MOUSE
θ value	0.163984 (rank : 320)	NC score	0.095052 (rank : 326)
Query Neighborhood Hits	498	Target Neighborhood Hits	171	Shared Neighborhood Hits	92
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV1_HUMAN
θ value	0.163984 (rank : 321)	NC score	0.221416 (rank : 311)
Query Neighborhood Hits	498	Target Neighborhood Hits	184	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_HUMAN
θ value	0.163984 (rank : 322)	NC score	0.204103 (rank : 315)
Query Neighborhood Hits	498	Target Neighborhood Hits	130	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ADA30_HUMAN
θ value	0.21417 (rank : 323)	NC score	0.017700 (rank : 467)
Query Neighborhood Hits	498	Target Neighborhood Hits	391	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LEO1_HUMAN
θ value	0.279714 (rank : 324)	NC score	0.042914 (rank : 394)
Query Neighborhood Hits	498	Target Neighborhood Hits	958	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAGE1_HUMAN
θ value	0.279714 (rank : 325)	NC score	0.032845 (rank : 427)
Query Neighborhood Hits	498	Target Neighborhood Hits	1389	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RAI1_MOUSE
θ value	0.279714 (rank : 326)	NC score	0.051454 (rank : 378)
Query Neighborhood Hits	498	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AKAP2_MOUSE
θ value	0.365318 (rank : 327)	NC score	0.025829 (rank : 440)
Query Neighborhood Hits	498	Target Neighborhood Hits	385	Shared Neighborhood Hits	32
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANKR9_MOUSE
θ value	0.365318 (rank : 328)	NC score	0.273716 (rank : 299)
Query Neighborhood Hits	498	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANR41_HUMAN
θ value	0.365318 (rank : 329)	NC score	0.702148 (rank : 158)
Query Neighborhood Hits	498	Target Neighborhood Hits	332	Shared Neighborhood Hits	261
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

BAT4_MOUSE
θ value	0.365318 (rank : 330)	NC score	0.271407 (rank : 302)
Query Neighborhood Hits	498	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

EP15R_MOUSE
θ value	0.365318 (rank : 331)	NC score	0.035011 (rank : 418)
Query Neighborhood Hits	498	Target Neighborhood Hits	1135	Shared Neighborhood Hits	68
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

IKBL_HUMAN
θ value	0.365318 (rank : 332)	NC score	0.326466 (rank : 285)
Query Neighborhood Hits	498	Target Neighborhood Hits	168	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

NPBL_MOUSE
θ value	0.365318 (rank : 333)	NC score	0.036854 (rank : 410)
Query Neighborhood Hits	498	Target Neighborhood Hits	1041	Shared Neighborhood Hits	83
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PEPL_HUMAN
θ value	0.365318 (rank : 334)	NC score	0.034943 (rank : 419)
Query Neighborhood Hits	498	Target Neighborhood Hits	1141	Shared Neighborhood Hits	72
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SCG3_MOUSE
θ value	0.365318 (rank : 335)	NC score	0.041007 (rank : 400)
Query Neighborhood Hits	498	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

TRPC3_MOUSE
θ value	0.365318 (rank : 336)	NC score	0.093224 (rank : 327)
Query Neighborhood Hits	498	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPV3_HUMAN
θ value	0.365318 (rank : 337)	NC score	0.233976 (rank : 306)
Query Neighborhood Hits	498	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	0.365318 (rank : 338)	NC score	0.236133 (rank : 305)
Query Neighborhood Hits	498	Target Neighborhood Hits	188	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

UBP51_HUMAN
θ value	0.365318 (rank : 339)	NC score	0.007620 (rank : 504)
Query Neighborhood Hits	498	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

ZN447_HUMAN
θ value	0.365318 (rank : 340)	NC score	-0.005972 (rank : 539)
Query Neighborhood Hits	498	Target Neighborhood Hits	899	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

BRD8_HUMAN
θ value	0.47712 (rank : 341)	NC score	0.034073 (rank : 423)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	0.47712 (rank : 342)	NC score	0.036609 (rank : 411)
Query Neighborhood Hits	498	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

EMIL3_MOUSE
θ value	0.47712 (rank : 343)	NC score	0.037163 (rank : 408)
Query Neighborhood Hits	498	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

MAST2_MOUSE
θ value	0.47712 (rank : 344)	NC score	0.005353 (rank : 513)
Query Neighborhood Hits	498	Target Neighborhood Hits	1110	Shared Neighborhood Hits	37
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MATR3_MOUSE
θ value	0.47712 (rank : 345)	NC score	0.026292 (rank : 438)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

NFH_MOUSE
θ value	0.47712 (rank : 346)	NC score	0.042756 (rank : 396)
Query Neighborhood Hits	498	Target Neighborhood Hits	2247	Shared Neighborhood Hits	150
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PININ_HUMAN
θ value	0.47712 (rank : 347)	NC score	0.048384 (rank : 384)
Query Neighborhood Hits	498	Target Neighborhood Hits	753	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	0.47712 (rank : 348)	NC score	0.053529 (rank : 361)
Query Neighborhood Hits	498	Target Neighborhood Hits	777	Shared Neighborhood Hits	79
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SYNC_MOUSE
θ value	0.47712 (rank : 349)	NC score	0.023994 (rank : 446)
Query Neighborhood Hits	498	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

ANR45_MOUSE
θ value	0.62314 (rank : 350)	NC score	0.561851 (rank : 205)
Query Neighborhood Hits	498	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

E41L2_MOUSE
θ value	0.62314 (rank : 351)	NC score	0.016248 (rank : 471)
Query Neighborhood Hits	498	Target Neighborhood Hits	459	Shared Neighborhood Hits	48
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

TCOF_HUMAN
θ value	0.62314 (rank : 352)	NC score	0.040305 (rank : 403)
Query Neighborhood Hits	498	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TXND2_HUMAN
θ value	0.62314 (rank : 353)	NC score	0.059118 (rank : 343)
Query Neighborhood Hits	498	Target Neighborhood Hits	793	Shared Neighborhood Hits	76
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ZAR1_MOUSE
θ value	0.62314 (rank : 354)	NC score	0.033960 (rank : 425)
Query Neighborhood Hits	498	Target Neighborhood Hits	254	Shared Neighborhood Hits	14
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ANKR9_HUMAN
θ value	0.813845 (rank : 355)	NC score	0.225844 (rank : 310)
Query Neighborhood Hits	498	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CCD45_HUMAN
θ value	0.813845 (rank : 356)	NC score	0.023382 (rank : 448)
Query Neighborhood Hits	498	Target Neighborhood Hits	525	Shared Neighborhood Hits	34
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

EVL_HUMAN
θ value	0.813845 (rank : 357)	NC score	0.033738 (rank : 426)
Query Neighborhood Hits	498	Target Neighborhood Hits	260	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

GLSK_HUMAN
θ value	0.813845 (rank : 358)	NC score	0.446208 (rank : 246)
Query Neighborhood Hits	498	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

LTBP2_MOUSE
θ value	0.813845 (rank : 359)	NC score	0.046857 (rank : 386)
Query Neighborhood Hits	498	Target Neighborhood Hits	617	Shared Neighborhood Hits	24
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NEK1_MOUSE
θ value	0.813845 (rank : 360)	NC score	0.006549 (rank : 508)
Query Neighborhood Hits	498	Target Neighborhood Hits	1311	Shared Neighborhood Hits	58
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SYNC_HUMAN
θ value	0.813845 (rank : 361)	NC score	0.023832 (rank : 447)
Query Neighborhood Hits	498	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

ARI4A_HUMAN
θ value	1.06291 (rank : 362)	NC score	0.048692 (rank : 383)
Query Neighborhood Hits	498	Target Neighborhood Hits	434	Shared Neighborhood Hits	56
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BAZ1B_HUMAN
θ value	1.06291 (rank : 363)	NC score	0.035233 (rank : 416)
Query Neighborhood Hits	498	Target Neighborhood Hits	701	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

DDEF1_MOUSE
θ value	1.06291 (rank : 364)	NC score	0.285176 (rank : 297)
Query Neighborhood Hits	498	Target Neighborhood Hits	592	Shared Neighborhood Hits	201
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

SAPS1_HUMAN
θ value	1.06291 (rank : 365)	NC score	0.023171 (rank : 449)
Query Neighborhood Hits	498	Target Neighborhood Hits	704	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TR150_MOUSE
θ value	1.06291 (rank : 366)	NC score	0.030778 (rank : 431)
Query Neighborhood Hits	498	Target Neighborhood Hits	468	Shared Neighborhood Hits	52
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRPV1_MOUSE
θ value	1.06291 (rank : 367)	NC score	0.231233 (rank : 307)
Query Neighborhood Hits	498	Target Neighborhood Hits	189	Shared Neighborhood Hits	158
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ANR45_HUMAN
θ value	1.38821 (rank : 368)	NC score	0.527137 (rank : 219)
Query Neighborhood Hits	498	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HOME2_MOUSE
θ value	1.38821 (rank : 369)	NC score	0.037465 (rank : 407)
Query Neighborhood Hits	498	Target Neighborhood Hits	882	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

LRRF1_HUMAN
θ value	1.38821 (rank : 370)	NC score	0.031290 (rank : 429)
Query Neighborhood Hits	498	Target Neighborhood Hits	625	Shared Neighborhood Hits	50
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

PCLO_MOUSE
θ value	1.38821 (rank : 371)	NC score	0.038357 (rank : 405)
Query Neighborhood Hits	498	Target Neighborhood Hits	2275	Shared Neighborhood Hits	120
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SEC63_HUMAN
θ value	1.38821 (rank : 372)	NC score	0.024963 (rank : 442)
Query Neighborhood Hits	498	Target Neighborhood Hits	586	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	1.38821 (rank : 373)	NC score	0.022680 (rank : 455)
Query Neighborhood Hits	498	Target Neighborhood Hits	601	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SESN1_HUMAN
θ value	1.38821 (rank : 374)	NC score	0.010904 (rank : 493)
Query Neighborhood Hits	498	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SMS2_HUMAN
θ value	1.38821 (rank : 375)	NC score	0.013390 (rank : 485)
Query Neighborhood Hits	498	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

TRM6_MOUSE
θ value	1.38821 (rank : 376)	NC score	0.023017 (rank : 452)
Query Neighborhood Hits	498	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CE96, Q3TJZ8, Q3TME7, Q6ZPW8, Q80Y59, Q8CEU0	Gene names	Trm6, Kiaa1153
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6).

ATX2_MOUSE
θ value	1.81305 (rank : 377)	NC score	0.031358 (rank : 428)
Query Neighborhood Hits	498	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CAC1C_HUMAN
θ value	1.81305 (rank : 378)	NC score	0.001930 (rank : 526)
Query Neighborhood Hits	498	Target Neighborhood Hits	158	Shared Neighborhood Hits	14
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

DNJC8_HUMAN
θ value	1.81305 (rank : 379)	NC score	0.014558 (rank : 477)
Query Neighborhood Hits	498	Target Neighborhood Hits	380	Shared Neighborhood Hits	21
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	1.81305 (rank : 380)	NC score	0.013688 (rank : 484)
Query Neighborhood Hits	498	Target Neighborhood Hits	392	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

EVL_MOUSE
θ value	1.81305 (rank : 381)	NC score	0.023027 (rank : 451)
Query Neighborhood Hits	498	Target Neighborhood Hits	203	Shared Neighborhood Hits	22
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

LRRK1_MOUSE
θ value	1.81305 (rank : 382)	NC score	0.076050 (rank : 334)
Query Neighborhood Hits	498	Target Neighborhood Hits	1267	Shared Neighborhood Hits	126
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MATR3_HUMAN
θ value	1.81305 (rank : 383)	NC score	0.022920 (rank : 453)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NUP53_HUMAN
θ value	1.81305 (rank : 384)	NC score	0.016672 (rank : 469)
Query Neighborhood Hits	498	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

RBBP6_HUMAN
θ value	1.81305 (rank : 385)	NC score	0.046305 (rank : 388)
Query Neighborhood Hits	498	Target Neighborhood Hits	1135	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TF3C1_MOUSE
θ value	1.81305 (rank : 386)	NC score	0.014924 (rank : 475)
Query Neighborhood Hits	498	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

XRN1_MOUSE
θ value	1.81305 (rank : 387)	NC score	0.009999 (rank : 497)
Query Neighborhood Hits	498	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

AR13B_HUMAN
θ value	2.36792 (rank : 388)	NC score	0.004912 (rank : 515)
Query Neighborhood Hits	498	Target Neighborhood Hits	528	Shared Neighborhood Hits	30
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

ATX2_HUMAN
θ value	2.36792 (rank : 389)	NC score	0.026030 (rank : 439)
Query Neighborhood Hits	498	Target Neighborhood Hits	375	Shared Neighborhood Hits	24
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CC47_MOUSE
θ value	2.36792 (rank : 390)	NC score	0.021355 (rank : 459)
Query Neighborhood Hits	498	Target Neighborhood Hits	245	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CN145_HUMAN
θ value	2.36792 (rank : 391)	NC score	0.029441 (rank : 432)
Query Neighborhood Hits	498	Target Neighborhood Hits	1196	Shared Neighborhood Hits	64
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DMN_HUMAN
θ value	2.36792 (rank : 392)	NC score	0.016453 (rank : 470)
Query Neighborhood Hits	498	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

FOXN3_HUMAN
θ value	2.36792 (rank : 393)	NC score	0.002283 (rank : 521)
Query Neighborhood Hits	498	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

GON4L_HUMAN
θ value	2.36792 (rank : 394)	NC score	0.021100 (rank : 461)
Query Neighborhood Hits	498	Target Neighborhood Hits	555	Shared Neighborhood Hits	52
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IWS1_MOUSE
θ value	2.36792 (rank : 395)	NC score	0.056542 (rank : 349)
Query Neighborhood Hits	498	Target Neighborhood Hits	1258	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRRF1_MOUSE
θ value	2.36792 (rank : 396)	NC score	0.028535 (rank : 434)
Query Neighborhood Hits	498	Target Neighborhood Hits	440	Shared Neighborhood Hits	39
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MBB1A_MOUSE
θ value	2.36792 (rank : 397)	NC score	0.022801 (rank : 454)
Query Neighborhood Hits	498	Target Neighborhood Hits	233	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

NSBP1_MOUSE
θ value	2.36792 (rank : 398)	NC score	0.041148 (rank : 399)
Query Neighborhood Hits	498	Target Neighborhood Hits	681	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SYP2L_MOUSE
θ value	2.36792 (rank : 399)	NC score	0.015319 (rank : 473)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TCRG1_HUMAN
θ value	2.36792 (rank : 400)	NC score	0.035766 (rank : 415)
Query Neighborhood Hits	498	Target Neighborhood Hits	929	Shared Neighborhood Hits	67
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	2.36792 (rank : 401)	NC score	0.034442 (rank : 421)
Query Neighborhood Hits	498	Target Neighborhood Hits	947	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TSP3_MOUSE
θ value	2.36792 (rank : 402)	NC score	0.036253 (rank : 413)
Query Neighborhood Hits	498	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CJ049_HUMAN
θ value	3.0926 (rank : 403)	NC score	0.022664 (rank : 456)
Query Neighborhood Hits	498	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

DJC12_HUMAN
θ value	3.0926 (rank : 404)	NC score	0.011041 (rank : 492)
Query Neighborhood Hits	498	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

DMP1_MOUSE
θ value	3.0926 (rank : 405)	NC score	0.044785 (rank : 390)
Query Neighborhood Hits	498	Target Neighborhood Hits	498	Shared Neighborhood Hits	63
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DMXL2_HUMAN
θ value	3.0926 (rank : 406)	NC score	-0.000396 (rank : 531)
Query Neighborhood Hits	498	Target Neighborhood Hits	374	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

GOGB1_HUMAN
θ value	3.0926 (rank : 407)	NC score	0.036862 (rank : 409)
Query Neighborhood Hits	498	Target Neighborhood Hits	2297	Shared Neighborhood Hits	120
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LSD1_HUMAN
θ value	3.0926 (rank : 408)	NC score	0.019982 (rank : 462)
Query Neighborhood Hits	498	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

RFC1_MOUSE
θ value	3.0926 (rank : 409)	NC score	0.022006 (rank : 457)
Query Neighborhood Hits	498	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SDPR_HUMAN
θ value	3.0926 (rank : 410)	NC score	0.010081 (rank : 495)
Query Neighborhood Hits	498	Target Neighborhood Hits	337	Shared Neighborhood Hits	23
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

TRPV2_MOUSE
θ value	3.0926 (rank : 411)	NC score	0.154627 (rank : 317)
Query Neighborhood Hits	498	Target Neighborhood Hits	111	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TSP3_HUMAN
θ value	3.0926 (rank : 412)	NC score	0.035198 (rank : 417)
Query Neighborhood Hits	498	Target Neighborhood Hits	250	Shared Neighborhood Hits	22
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ZHX2_MOUSE
θ value	3.0926 (rank : 413)	NC score	0.002146 (rank : 523)
Query Neighborhood Hits	498	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZN394_MOUSE
θ value	3.0926 (rank : 414)	NC score	-0.013979 (rank : 544)
Query Neighborhood Hits	498	Target Neighborhood Hits	738	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1D9, Q3U4Z1, Q9CYV9, Q9CZG8	Gene names	Znf394, Zfp94, Zfp99
Domain Architecture
Description	Zinc finger protein 394 (Zinc finger protein 94) (Zfp-94).

GPR32_HUMAN
θ value	4.03905 (rank : 415)	NC score	-0.009973 (rank : 541)
Query Neighborhood Hits	498	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	O75388, Q6NWS5	Gene names	GPR32
Domain Architecture
Description	Probable G-protein coupled receptor 32.

K0460_MOUSE
θ value	4.03905 (rank : 416)	NC score	0.019897 (rank : 464)
Query Neighborhood Hits	498	Target Neighborhood Hits	374	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KR10C_HUMAN
θ value	4.03905 (rank : 417)	NC score	0.043473 (rank : 393)
Query Neighborhood Hits	498	Target Neighborhood Hits	219	Shared Neighborhood Hits	16
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

NEIL3_MOUSE
θ value	4.03905 (rank : 418)	NC score	0.014336 (rank : 478)
Query Neighborhood Hits	498	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

PCD12_MOUSE
θ value	4.03905 (rank : 419)	NC score	-0.005041 (rank : 538)
Query Neighborhood Hits	498	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

PCGF4_HUMAN
θ value	4.03905 (rank : 420)	NC score	0.013865 (rank : 481)
Query Neighborhood Hits	498	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	4.03905 (rank : 421)	NC score	0.013769 (rank : 482)
Query Neighborhood Hits	498	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RGS3_MOUSE
θ value	4.03905 (rank : 422)	NC score	0.027781 (rank : 437)
Query Neighborhood Hits	498	Target Neighborhood Hits	1621	Shared Neighborhood Hits	90
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SEPT7_HUMAN
θ value	4.03905 (rank : 423)	NC score	0.007368 (rank : 505)
Query Neighborhood Hits	498	Target Neighborhood Hits	385	Shared Neighborhood Hits	25
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SH24A_MOUSE
θ value	4.03905 (rank : 424)	NC score	0.011568 (rank : 488)
Query Neighborhood Hits	498	Target Neighborhood Hits	326	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SMYD3_HUMAN
θ value	4.03905 (rank : 425)	NC score	0.036266 (rank : 412)
Query Neighborhood Hits	498	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SVIL_MOUSE
θ value	4.03905 (rank : 426)	NC score	0.018304 (rank : 465)
Query Neighborhood Hits	498	Target Neighborhood Hits	439	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TCAL3_HUMAN
θ value	4.03905 (rank : 427)	NC score	0.023103 (rank : 450)
Query Neighborhood Hits	498	Target Neighborhood Hits	274	Shared Neighborhood Hits	27
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TNIP3_HUMAN
θ value	4.03905 (rank : 428)	NC score	0.024625 (rank : 444)
Query Neighborhood Hits	498	Target Neighborhood Hits	511	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TRPC5_MOUSE
θ value	4.03905 (rank : 429)	NC score	0.079595 (rank : 332)
Query Neighborhood Hits	498	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

ZN687_HUMAN
θ value	4.03905 (rank : 430)	NC score	-0.002478 (rank : 537)
Query Neighborhood Hits	498	Target Neighborhood Hits	1244	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CCD55_HUMAN
θ value	5.27518 (rank : 431)	NC score	0.029047 (rank : 433)
Query Neighborhood Hits	498	Target Neighborhood Hits	513	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CO1A1_HUMAN
θ value	5.27518 (rank : 432)	NC score	0.013989 (rank : 480)
Query Neighborhood Hits	498	Target Neighborhood Hits	475	Shared Neighborhood Hits	32
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO7A1_HUMAN
θ value	5.27518 (rank : 433)	NC score	0.002020 (rank : 525)
Query Neighborhood Hits	498	Target Neighborhood Hits	807	Shared Neighborhood Hits	41
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CUBN_HUMAN
θ value	5.27518 (rank : 434)	NC score	0.038714 (rank : 404)
Query Neighborhood Hits	498	Target Neighborhood Hits	482	Shared Neighborhood Hits	17
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DHX34_MOUSE
θ value	5.27518 (rank : 435)	NC score	-0.000955 (rank : 532)
Query Neighborhood Hits	498	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

F10A1_HUMAN
θ value	5.27518 (rank : 436)	NC score	0.015815 (rank : 472)
Query Neighborhood Hits	498	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

F10A4_HUMAN
θ value	5.27518 (rank : 437)	NC score	0.015168 (rank : 474)
Query Neighborhood Hits	498	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

FLNA_HUMAN
θ value	5.27518 (rank : 438)	NC score	0.001022 (rank : 528)
Query Neighborhood Hits	498	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
θ value	5.27518 (rank : 439)	NC score	0.001062 (rank : 527)
Query Neighborhood Hits	498	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

IF4E3_MOUSE
θ value	5.27518 (rank : 440)	NC score	0.011055 (rank : 491)
Query Neighborhood Hits	498	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMB3, O88503, Q3UCK2	Gene names	Eif4el3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP).

MAP1A_HUMAN
θ value	5.27518 (rank : 441)	NC score	0.040606 (rank : 402)
Query Neighborhood Hits	498	Target Neighborhood Hits	1626	Shared Neighborhood Hits	109
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MDN1_HUMAN
θ value	5.27518 (rank : 442)	NC score	0.041710 (rank : 398)
Query Neighborhood Hits	498	Target Neighborhood Hits	662	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MUCDL_MOUSE
θ value	5.27518 (rank : 443)	NC score	0.017131 (rank : 468)
Query Neighborhood Hits	498	Target Neighborhood Hits	461	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RP1L1_HUMAN
θ value	5.27518 (rank : 444)	NC score	0.042724 (rank : 397)
Query Neighborhood Hits	498	Target Neighborhood Hits	1072	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SCG3_HUMAN
θ value	5.27518 (rank : 445)	NC score	0.028249 (rank : 435)
Query Neighborhood Hits	498	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXD2, Q96C83, Q96GE8, Q9Y6G7	Gene names	SCG3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

SDCG8_MOUSE
θ value	5.27518 (rank : 446)	NC score	0.024822 (rank : 443)
Query Neighborhood Hits	498	Target Neighborhood Hits	886	Shared Neighborhood Hits	51
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SEMG1_HUMAN
θ value	5.27518 (rank : 447)	NC score	0.007870 (rank : 502)
Query Neighborhood Hits	498	Target Neighborhood Hits	200	Shared Neighborhood Hits	15
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

TACC1_MOUSE
θ value	5.27518 (rank : 448)	NC score	0.034911 (rank : 420)
Query Neighborhood Hits	498	Target Neighborhood Hits	667	Shared Neighborhood Hits	48
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TCGAP_MOUSE
θ value	5.27518 (rank : 449)	NC score	0.014714 (rank : 476)
Query Neighborhood Hits	498	Target Neighborhood Hits	409	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRPC5_HUMAN
θ value	5.27518 (rank : 450)	NC score	0.078335 (rank : 333)
Query Neighborhood Hits	498	Target Neighborhood Hits	122	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

ZN683_HUMAN
θ value	5.27518 (rank : 451)	NC score	-0.013883 (rank : 543)
Query Neighborhood Hits	498	Target Neighborhood Hits	750	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

ZNFX1_MOUSE
θ value	5.27518 (rank : 452)	NC score	0.008535 (rank : 499)
Query Neighborhood Hits	498	Target Neighborhood Hits	407	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADA28_MOUSE
θ value	6.88961 (rank : 453)	NC score	0.005924 (rank : 511)
Query Neighborhood Hits	498	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADRB1_HUMAN
θ value	6.88961 (rank : 454)	NC score	-0.014067 (rank : 545)
Query Neighborhood Hits	498	Target Neighborhood Hits	866	Shared Neighborhood Hits	4
SwissProt Accessions	P08588, Q9UKG7, Q9UKG8	Gene names	ADRB1, ADRB1R, B1AR
Domain Architecture
Description	Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1 adrenoreceptor).

ANKZ1_HUMAN
θ value	6.88961 (rank : 455)	NC score	0.289339 (rank : 295)
Query Neighborhood Hits	498	Target Neighborhood Hits	236	Shared Neighborhood Hits	163
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

AQR_HUMAN
θ value	6.88961 (rank : 456)	NC score	0.004792 (rank : 516)
Query Neighborhood Hits	498	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

ATS8_MOUSE
θ value	6.88961 (rank : 457)	NC score	-0.002464 (rank : 536)
Query Neighborhood Hits	498	Target Neighborhood Hits	139	Shared Neighborhood Hits	6
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

CJ012_HUMAN
θ value	6.88961 (rank : 458)	NC score	0.024045 (rank : 445)
Query Neighborhood Hits	498	Target Neighborhood Hits	467	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CLGN_MOUSE
θ value	6.88961 (rank : 459)	NC score	0.007227 (rank : 506)
Query Neighborhood Hits	498	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

COHA1_MOUSE
θ value	6.88961 (rank : 460)	NC score	0.008483 (rank : 500)
Query Neighborhood Hits	498	Target Neighborhood Hits	414	Shared Neighborhood Hits	33
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CSPG5_MOUSE
θ value	6.88961 (rank : 461)	NC score	0.006372 (rank : 509)
Query Neighborhood Hits	498	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

ETV1_HUMAN
θ value	6.88961 (rank : 462)	NC score	0.002352 (rank : 520)
Query Neighborhood Hits	498	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

F10A5_HUMAN
θ value	6.88961 (rank : 463)	NC score	0.013189 (rank : 486)
Query Neighborhood Hits	498	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

GHR_MOUSE
θ value	6.88961 (rank : 464)	NC score	0.003639 (rank : 519)
Query Neighborhood Hits	498	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

IF2M_MOUSE
θ value	6.88961 (rank : 465)	NC score	0.007138 (rank : 507)
Query Neighborhood Hits	498	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

ITA1_HUMAN
θ value	6.88961 (rank : 466)	NC score	-0.001588 (rank : 534)
Query Neighborhood Hits	498	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	P56199	Gene names	ITGA1
Domain Architecture	No domain graphic available
Description	Integrin alpha-1 (Laminin and collagen receptor) (VLA-1) (CD49a antigen).

MAP2_MOUSE
θ value	6.88961 (rank : 467)	NC score	0.018064 (rank : 466)
Query Neighborhood Hits	498	Target Neighborhood Hits	342	Shared Neighborhood Hits	44
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MYLK_MOUSE
θ value	6.88961 (rank : 468)	NC score	0.006294 (rank : 510)
Query Neighborhood Hits	498	Target Neighborhood Hits	1489	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

SCG2_HUMAN
θ value	6.88961 (rank : 469)	NC score	0.021116 (rank : 460)
Query Neighborhood Hits	498	Target Neighborhood Hits	190	Shared Neighborhood Hits	25
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SOX7_MOUSE
θ value	6.88961 (rank : 470)	NC score	-0.002233 (rank : 535)
Query Neighborhood Hits	498	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SPAST_MOUSE
θ value	6.88961 (rank : 471)	NC score	-0.001446 (rank : 533)
Query Neighborhood Hits	498	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SREC2_HUMAN
θ value	6.88961 (rank : 472)	NC score	0.046741 (rank : 387)
Query Neighborhood Hits	498	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SRPK1_MOUSE
θ value	6.88961 (rank : 473)	NC score	0.000058 (rank : 530)
Query Neighborhood Hits	498	Target Neighborhood Hits	639	Shared Neighborhood Hits	22
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TSH1_MOUSE
θ value	6.88961 (rank : 474)	NC score	0.000917 (rank : 529)
Query Neighborhood Hits	498	Target Neighborhood Hits	675	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

TTC1_HUMAN
θ value	6.88961 (rank : 475)	NC score	0.008000 (rank : 501)
Query Neighborhood Hits	498	Target Neighborhood Hits	417	Shared Neighborhood Hits	27
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

AAAD_MOUSE
θ value	8.99809 (rank : 476)	NC score	0.003639 (rank : 518)
Query Neighborhood Hits	498	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AGGF1_HUMAN
θ value	8.99809 (rank : 477)	NC score	0.007655 (rank : 503)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

ANKF1_HUMAN
θ value	8.99809 (rank : 478)	NC score	0.128730 (rank : 319)
Query Neighborhood Hits	498	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

BAT4_HUMAN
θ value	8.99809 (rank : 479)	NC score	0.230017 (rank : 308)
Query Neighborhood Hits	498	Target Neighborhood Hits	157	Shared Neighborhood Hits	111
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BSCL2_MOUSE
θ value	8.99809 (rank : 480)	NC score	0.004024 (rank : 517)
Query Neighborhood Hits	498	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

CEP57_MOUSE
θ value	8.99809 (rank : 481)	NC score	0.019916 (rank : 463)
Query Neighborhood Hits	498	Target Neighborhood Hits	580	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CGRE1_HUMAN
θ value	8.99809 (rank : 482)	NC score	0.011536 (rank : 489)
Query Neighborhood Hits	498	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CI093_HUMAN
θ value	8.99809 (rank : 483)	NC score	0.021397 (rank : 458)
Query Neighborhood Hits	498	Target Neighborhood Hits	1088	Shared Neighborhood Hits	56
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

ETV1_MOUSE
θ value	8.99809 (rank : 484)	NC score	0.002196 (rank : 522)
Query Neighborhood Hits	498	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

GGA1_HUMAN
θ value	8.99809 (rank : 485)	NC score	0.009268 (rank : 498)
Query Neighborhood Hits	498	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

HDAC9_MOUSE
θ value	8.99809 (rank : 486)	NC score	0.005903 (rank : 512)
Query Neighborhood Hits	498	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

HV3B_HUMAN
θ value	8.99809 (rank : 487)	NC score	-0.006752 (rank : 540)
Query Neighborhood Hits	498	Target Neighborhood Hits	253	Shared Neighborhood Hits	2
SwissProt Accessions	P01763	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region WEA.

IDLC_HUMAN
θ value	8.99809 (rank : 488)	NC score	0.013710 (rank : 483)
Query Neighborhood Hits	498	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	8.99809 (rank : 489)	NC score	0.014152 (rank : 479)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

JHD2C_MOUSE
θ value	8.99809 (rank : 490)	NC score	0.011409 (rank : 490)
Query Neighborhood Hits	498	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MAST1_HUMAN
θ value	8.99809 (rank : 491)	NC score	0.004925 (rank : 514)
Query Neighborhood Hits	498	Target Neighborhood Hits	1146	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MATN2_MOUSE
θ value	8.99809 (rank : 492)	NC score	0.030907 (rank : 430)
Query Neighborhood Hits	498	Target Neighborhood Hits	356	Shared Neighborhood Hits	21
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MERL_HUMAN
θ value	8.99809 (rank : 493)	NC score	0.010067 (rank : 496)
Query Neighborhood Hits	498	Target Neighborhood Hits	532	Shared Neighborhood Hits	32
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

OAS3_HUMAN
θ value	8.99809 (rank : 494)	NC score	0.002072 (rank : 524)
Query Neighborhood Hits	498	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

PHF20_MOUSE
θ value	8.99809 (rank : 495)	NC score	0.025291 (rank : 441)
Query Neighborhood Hits	498	Target Neighborhood Hits	513	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PKHA2_HUMAN
θ value	8.99809 (rank : 496)	NC score	0.010810 (rank : 494)
Query Neighborhood Hits	498	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

SREC2_MOUSE
θ value	8.99809 (rank : 497)	NC score	0.047222 (rank : 385)
Query Neighborhood Hits	498	Target Neighborhood Hits	605	Shared Neighborhood Hits	37
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ZNFX1_HUMAN
θ value	8.99809 (rank : 498)	NC score	0.012010 (rank : 487)
Query Neighborhood Hits	498	Target Neighborhood Hits	308	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ARFG1_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.051370 (rank : 379)
Query Neighborhood Hits	498	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.052976 (rank : 367)
Query Neighborhood Hits	498	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.053269 (rank : 364)
Query Neighborhood Hits	498	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.054183 (rank : 356)
Query Neighborhood Hits	498	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

BASP_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.061602 (rank : 338)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	50
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.057531 (rank : 347)
Query Neighborhood Hits	498	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CENA1_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.056261 (rank : 352)
Query Neighborhood Hits	498	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.051707 (rank : 376)
Query Neighborhood Hits	498	Target Neighborhood Hits	83	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.052485 (rank : 371)
Query Neighborhood Hits	498	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CMTA1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.173491 (rank : 316)
Query Neighborhood Hits	498	Target Neighborhood Hits	217	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.134845 (rank : 318)
Query Neighborhood Hits	498	Target Neighborhood Hits	199	Shared Neighborhood Hits	93
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.123254 (rank : 320)
Query Neighborhood Hits	498	Target Neighborhood Hits	216	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CRUM2_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.051082 (rank : 381)
Query Neighborhood Hits	498	Target Neighborhood Hits	453	Shared Neighborhood Hits	20
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CU081_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.112898 (rank : 323)
Query Neighborhood Hits	498	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

CYLC1_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.051708 (rank : 375)
Query Neighborhood Hits	498	Target Neighborhood Hits	408	Shared Neighborhood Hits	65
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DNER_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.052321 (rank : 372)
Query Neighborhood Hits	498	Target Neighborhood Hits	460	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.052875 (rank : 368)
Query Neighborhood Hits	498	Target Neighborhood Hits	413	Shared Neighborhood Hits	20
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

IF2P_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.052042 (rank : 373)
Query Neighborhood Hits	498	Target Neighborhood Hits	889	Shared Neighborhood Hits	105
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

JAG1_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.053275 (rank : 363)
Query Neighborhood Hits	498	Target Neighborhood Hits	514	Shared Neighborhood Hits	22
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.053291 (rank : 362)
Query Neighborhood Hits	498	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.052774 (rank : 369)
Query Neighborhood Hits	498	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.054147 (rank : 357)
Query Neighborhood Hits	498	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LCE1B_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.057228 (rank : 348)
Query Neighborhood Hits	498	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.059237 (rank : 340)
Query Neighborhood Hits	498	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.062318 (rank : 337)
Query Neighborhood Hits	498	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.056154 (rank : 354)
Query Neighborhood Hits	498	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LRRK1_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.051176 (rank : 380)
Query Neighborhood Hits	498	Target Neighborhood Hits	1237	Shared Neighborhood Hits	100
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MDC1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.053926 (rank : 358)
Query Neighborhood Hits	498	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NACAM_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.051456 (rank : 377)
Query Neighborhood Hits	498	Target Neighborhood Hits	1866	Shared Neighborhood Hits	102
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRP1_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.052978 (rank : 366)
Query Neighborhood Hits	498	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PTMA_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.053758 (rank : 359)
Query Neighborhood Hits	498	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RSF1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.052029 (rank : 374)
Query Neighborhood Hits	498	Target Neighborhood Hits	539	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SMAP1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.056221 (rank : 353)
Query Neighborhood Hits	498	Target Neighborhood Hits	98	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.058401 (rank : 345)
Query Neighborhood Hits	498	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.056366 (rank : 350)
Query Neighborhood Hits	498	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.058981 (rank : 344)
Query Neighborhood Hits	498	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRRM1_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.054954 (rank : 355)
Query Neighborhood Hits	498	Target Neighborhood Hits	690	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.059680 (rank : 339)
Query Neighborhood Hits	498	Target Neighborhood Hits	966	Shared Neighborhood Hits	89
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.056335 (rank : 351)
Query Neighborhood Hits	498	Target Neighborhood Hits	1296	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SSB4_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.050970 (rank : 382)
Query Neighborhood Hits	498	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

TRDN_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.067242 (rank : 336)
Query Neighborhood Hits	498	Target Neighborhood Hits	542	Shared Neighborhood Hits	77
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.058234 (rank : 346)
Query Neighborhood Hits	498	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.053080 (rank : 365)
Query Neighborhood Hits	498	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC7_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.085198 (rank : 329)
Query Neighborhood Hits	498	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.085685 (rank : 328)
Query Neighborhood Hits	498	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPV4_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.122850 (rank : 322)
Query Neighborhood Hits	498	Target Neighborhood Hits	150	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.108966 (rank : 324)
Query Neighborhood Hits	498	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

EHMT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	498	Target Neighborhood Hits	498	Shared Neighborhood Hits	498
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.981392 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	498	Target Neighborhood Hits	417	Shared Neighborhood Hits	330
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_MOUSE
NC score	0.980498 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	498	Target Neighborhood Hits	750	Shared Neighborhood Hits	428
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR29_HUMAN
NC score	0.868957 (rank : 4)	θ value	7.82807e-20 (rank : 36)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	291
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.868909 (rank : 5)	θ value	4.29542e-18 (rank : 44)
Query Neighborhood Hits	498	Target Neighborhood Hits	301	Shared Neighborhood Hits	295
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.866433 (rank : 6)	θ value	1.38178e-16 (rank : 59)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.866283 (rank : 7)	θ value	4.28545e-26 (rank : 14)
Query Neighborhood Hits	498	Target Neighborhood Hits	439	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR50_HUMAN
NC score	0.859834 (rank : 8)	θ value	4.01107e-24 (rank : 19)
Query Neighborhood Hits	498	Target Neighborhood Hits	361	Shared Neighborhood Hits	301
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR28_MOUSE
NC score	0.853986 (rank : 9)	θ value	1.6813e-30 (rank : 8)
Query Neighborhood Hits	498	Target Neighborhood Hits	314	Shared Neighborhood Hits	302
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR44_HUMAN
NC score	0.853624 (rank : 10)	θ value	5.06226e-27 (rank : 11)
Query Neighborhood Hits	498	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR16_HUMAN
NC score	0.852983 (rank : 11)	θ value	9.90251e-15 (rank : 84)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	281
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR28_HUMAN
NC score	0.852258 (rank : 12)	θ value	9.2256e-29 (rank : 9)
Query Neighborhood Hits	498	Target Neighborhood Hits	314	Shared Neighborhood Hits	302
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

INVS_HUMAN
NC score	0.849051 (rank : 13)	θ value	1.37858e-24 (rank : 18)
Query Neighborhood Hits	498	Target Neighborhood Hits	455	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANKR2_MOUSE
NC score	0.849035 (rank : 14)	θ value	8.10077e-17 (rank : 54)
Query Neighborhood Hits	498	Target Neighborhood Hits	312	Shared Neighborhood Hits	291
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ASB3_HUMAN
NC score	0.848955 (rank : 15)	θ value	2.06002e-20 (rank : 34)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_MOUSE
NC score	0.846977 (rank : 16)	θ value	6.62687e-19 (rank : 39)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	294
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB10_HUMAN
NC score	0.846148 (rank : 17)	θ value	5.42112e-21 (rank : 32)
Query Neighborhood Hits	498	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

FANK1_HUMAN
NC score	0.846100 (rank : 18)	θ value	2.88119e-14 (rank : 91)
Query Neighborhood Hits	498	Target Neighborhood Hits	326	Shared Neighborhood Hits	290
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANKR2_HUMAN
NC score	0.845656 (rank : 19)	θ value	6.85773e-16 (rank : 65)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	293
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR42_MOUSE
NC score	0.844507 (rank : 20)	θ value	5.99374e-20 (rank : 35)
Query Neighborhood Hits	498	Target Neighborhood Hits	334	Shared Neighborhood Hits	285
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

FANK1_MOUSE
NC score	0.844137 (rank : 21)	θ value	1.68911e-14 (rank : 90)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	285
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

INVS_MOUSE
NC score	0.843834 (rank : 22)	θ value	2.12685e-25 (rank : 15)
Query Neighborhood Hits	498	Target Neighborhood Hits	609	Shared Neighborhood Hits	314
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

TNKS1_HUMAN
NC score	0.843387 (rank : 23)	θ value	9.87957e-23 (rank : 26)
Query Neighborhood Hits	498	Target Neighborhood Hits	477	Shared Neighborhood Hits	312
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR52_MOUSE
NC score	0.843185 (rank : 24)	θ value	3.39556e-23 (rank : 24)
Query Neighborhood Hits	498	Target Neighborhood Hits	318	Shared Neighborhood Hits	304
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.843127 (rank : 25)	θ value	4.43474e-23 (rank : 25)
Query Neighborhood Hits	498	Target Neighborhood Hits	322	Shared Neighborhood Hits	304
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNKS2_HUMAN
NC score	0.842513 (rank : 26)	θ value	2.87452e-22 (rank : 28)
Query Neighborhood Hits	498	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ASB10_MOUSE
NC score	0.841717 (rank : 27)	θ value	1.47631e-18 (rank : 41)
Query Neighborhood Hits	498	Target Neighborhood Hits	301	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR23_MOUSE
NC score	0.841343 (rank : 28)	θ value	1.2105e-12 (rank : 123)
Query Neighborhood Hits	498	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR23_HUMAN
NC score	0.841238 (rank : 29)	θ value	5.43371e-13 (rank : 112)
Query Neighborhood Hits	498	Target Neighborhood Hits	291	Shared Neighborhood Hits	287
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANKR1_HUMAN
NC score	0.840416 (rank : 30)	θ value	1.29331e-14 (rank : 87)
Query Neighborhood Hits	498	Target Neighborhood Hits	308	Shared Neighborhood Hits	285
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ASB8_MOUSE
NC score	0.840355 (rank : 31)	θ value	9.26847e-13 (rank : 120)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANK1_HUMAN
NC score	0.839812 (rank : 32)	θ value	3.28125e-26 (rank : 12)
Query Neighborhood Hits	498	Target Neighborhood Hits	416	Shared Neighborhood Hits	310
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANKR1_MOUSE
NC score	0.839765 (rank : 33)	θ value	1.68911e-14 (rank : 89)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	291
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB8_HUMAN
NC score	0.839546 (rank : 34)	θ value	7.09661e-13 (rank : 115)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	287
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR49_MOUSE
NC score	0.839232 (rank : 35)	θ value	8.38298e-14 (rank : 101)
Query Neighborhood Hits	498	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANK1_MOUSE
NC score	0.838987 (rank : 36)	θ value	3.28125e-26 (rank : 13)
Query Neighborhood Hits	498	Target Neighborhood Hits	430	Shared Neighborhood Hits	311
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ASB13_MOUSE
NC score	0.836282 (rank : 37)	θ value	2.60593e-15 (rank : 76)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB2_HUMAN
NC score	0.836265 (rank : 38)	θ value	1.058e-16 (rank : 56)
Query Neighborhood Hits	498	Target Neighborhood Hits	309	Shared Neighborhood Hits	291
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB13_HUMAN
NC score	0.835893 (rank : 39)	θ value	2.60593e-15 (rank : 75)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB7_MOUSE
NC score	0.834866 (rank : 40)	θ value	2.69671e-12 (rank : 133)
Query Neighborhood Hits	498	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.834862 (rank : 41)	θ value	2.69671e-12 (rank : 132)
Query Neighborhood Hits	498	Target Neighborhood Hits	296	Shared Neighborhood Hits	286
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR49_HUMAN
NC score	0.832801 (rank : 42)	θ value	6.00763e-12 (rank : 139)
Query Neighborhood Hits	498	Target Neighborhood Hits	282	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR42_HUMAN
NC score	0.832190 (rank : 43)	θ value	1.42992e-13 (rank : 102)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANK3_HUMAN
NC score	0.831760 (rank : 44)	θ value	3.87602e-27 (rank : 10)
Query Neighborhood Hits	498	Target Neighborhood Hits	853	Shared Neighborhood Hits	340
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR39_HUMAN
NC score	0.831086 (rank : 45)	θ value	2.79066e-09 (rank : 183)
Query Neighborhood Hits	498	Target Neighborhood Hits	285	Shared Neighborhood Hits	283
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB2_MOUSE
NC score	0.829067 (rank : 46)	θ value	1.52774e-15 (rank : 70)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR39_MOUSE
NC score	0.827922 (rank : 47)	θ value	2.79066e-09 (rank : 184)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

BCL3_HUMAN
NC score	0.825252 (rank : 48)	θ value	3.76295e-14 (rank : 94)
Query Neighborhood Hits	498	Target Neighborhood Hits	324	Shared Neighborhood Hits	291
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

GABP2_MOUSE
NC score	0.820621 (rank : 49)	θ value	9.59137e-10 (rank : 171)
Query Neighborhood Hits	498	Target Neighborhood Hits	429	Shared Neighborhood Hits	288
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

BCL3_MOUSE
NC score	0.820336 (rank : 50)	θ value	2.43908e-13 (rank : 107)
Query Neighborhood Hits	498	Target Neighborhood Hits	388	Shared Neighborhood Hits	292
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

MTPN_MOUSE
NC score	0.820298 (rank : 51)	θ value	2.36244e-08 (rank : 204)
Query Neighborhood Hits	498	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

PA2G6_MOUSE
NC score	0.819865 (rank : 52)	θ value	1.29331e-14 (rank : 88)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

TRPA1_MOUSE
NC score	0.819404 (rank : 53)	θ value	7.09661e-13 (rank : 117)
Query Neighborhood Hits	498	Target Neighborhood Hits	343	Shared Neighborhood Hits	295
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANKR7_HUMAN
NC score	0.818918 (rank : 54)	θ value	2.0648e-12 (rank : 125)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	283
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

GABP2_HUMAN
NC score	0.818563 (rank : 55)	θ value	9.59137e-10 (rank : 170)
Query Neighborhood Hits	498	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

MTPN_HUMAN
NC score	0.818241 (rank : 56)	θ value	2.36244e-08 (rank : 203)
Query Neighborhood Hits	498	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

GABP3_MOUSE
NC score	0.817296 (rank : 57)	θ value	6.21693e-09 (rank : 192)
Query Neighborhood Hits	498	Target Neighborhood Hits	330	Shared Neighborhood Hits	278
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANKS3_MOUSE
NC score	0.817175 (rank : 58)	θ value	2.69671e-12 (rank : 131)
Query Neighborhood Hits	498	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASZ1_MOUSE
NC score	0.817106 (rank : 59)	θ value	1.74796e-11 (rank : 148)
Query Neighborhood Hits	498	Target Neighborhood Hits	319	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TRPA1_HUMAN
NC score	0.816803 (rank : 60)	θ value	2.43908e-13 (rank : 109)
Query Neighborhood Hits	498	Target Neighborhood Hits	339	Shared Neighborhood Hits	298
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

RFXK_HUMAN
NC score	0.816087 (rank : 61)	θ value	3.76295e-14 (rank : 96)
Query Neighborhood Hits	498	Target Neighborhood Hits	282	Shared Neighborhood Hits	267
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANRA2_HUMAN
NC score	0.814238 (rank : 62)	θ value	7.09661e-13 (rank : 114)
Query Neighborhood Hits	498	Target Neighborhood Hits	288	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
NC score	0.813679 (rank : 63)	θ value	9.26847e-13 (rank : 119)
Query Neighborhood Hits	498	Target Neighborhood Hits	287	Shared Neighborhood Hits	279
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANKS3_HUMAN
NC score	0.813309 (rank : 64)	θ value	7.84624e-12 (rank : 143)
Query Neighborhood Hits	498	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

PA2G6_HUMAN
NC score	0.813111 (rank : 65)	θ value	2.0648e-12 (rank : 129)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	282
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASZ1_HUMAN
NC score	0.813097 (rank : 66)	θ value	6.00763e-12 (rank : 140)
Query Neighborhood Hits	498	Target Neighborhood Hits	341	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKR5_MOUSE
NC score	0.812477 (rank : 67)	θ value	7.84624e-12 (rank : 142)
Query Neighborhood Hits	498	Target Neighborhood Hits	298	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_HUMAN
NC score	0.812014 (rank : 68)	θ value	7.84624e-12 (rank : 141)
Query Neighborhood Hits	498	Target Neighborhood Hits	297	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB16_MOUSE
NC score	0.811046 (rank : 69)	θ value	2.52405e-10 (rank : 166)
Query Neighborhood Hits	498	Target Neighborhood Hits	306	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MYPT1_MOUSE
NC score	0.809401 (rank : 70)	θ value	9.90251e-15 (rank : 85)
Query Neighborhood Hits	498	Target Neighborhood Hits	539	Shared Neighborhood Hits	321
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ASB15_HUMAN
NC score	0.809192 (rank : 71)	θ value	3.76295e-14 (rank : 93)
Query Neighborhood Hits	498	Target Neighborhood Hits	305	Shared Neighborhood Hits	286
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

RFXK_MOUSE
NC score	0.807666 (rank : 72)	θ value	2.0648e-12 (rank : 130)
Query Neighborhood Hits	498	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

PP16A_MOUSE
NC score	0.807234 (rank : 73)	θ value	4.16044e-13 (rank : 110)
Query Neighborhood Hits	498	Target Neighborhood Hits	318	Shared Neighborhood Hits	287
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANKS1_HUMAN
NC score	0.806991 (rank : 74)	θ value	5.60996e-18 (rank : 45)
Query Neighborhood Hits	498	Target Neighborhood Hits	438	Shared Neighborhood Hits	303
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CDN2C_MOUSE
NC score	0.806344 (rank : 75)	θ value	3.29651e-10 (rank : 167)
Query Neighborhood Hits	498	Target Neighborhood Hits	270	Shared Neighborhood Hits	270
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

MIB1_HUMAN
NC score	0.806190 (rank : 76)	θ value	1.80466e-16 (rank : 61)
Query Neighborhood Hits	498	Target Neighborhood Hits	470	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

AN36B_HUMAN
NC score	0.805698 (rank : 77)	θ value	1.99529e-15 (rank : 71)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	286
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ASB11_MOUSE
NC score	0.805550 (rank : 78)	θ value	1.80466e-16 (rank : 60)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

MIB1_MOUSE
NC score	0.805274 (rank : 79)	θ value	1.38178e-16 (rank : 58)
Query Neighborhood Hits	498	Target Neighborhood Hits	471	Shared Neighborhood Hits	297
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB2_HUMAN
NC score	0.804626 (rank : 80)	θ value	1.2077e-20 (rank : 33)
Query Neighborhood Hits	498	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CDN2C_HUMAN
NC score	0.804509 (rank : 81)	θ value	1.25267e-09 (rank : 174)
Query Neighborhood Hits	498	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ASB16_HUMAN
NC score	0.804188 (rank : 82)	θ value	5.62301e-10 (rank : 169)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	274
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB11_HUMAN
NC score	0.804066 (rank : 83)	θ value	6.85773e-16 (rank : 67)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB5_HUMAN
NC score	0.803650 (rank : 84)	θ value	1.99529e-15 (rank : 72)
Query Neighborhood Hits	498	Target Neighborhood Hits	283	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR10_MOUSE
NC score	0.803583 (rank : 85)	θ value	2.43908e-13 (rank : 106)
Query Neighborhood Hits	498	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB9_HUMAN
NC score	0.802565 (rank : 86)	θ value	1.42992e-13 (rank : 103)
Query Neighborhood Hits	498	Target Neighborhood Hits	267	Shared Neighborhood Hits	258
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MIB2_MOUSE
NC score	0.802169 (rank : 87)	θ value	1.02238e-19 (rank : 37)
Query Neighborhood Hits	498	Target Neighborhood Hits	409	Shared Neighborhood Hits	284
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR10_HUMAN
NC score	0.801881 (rank : 88)	θ value	9.26847e-13 (rank : 118)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	269
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANKS6_MOUSE
NC score	0.800730 (rank : 89)	θ value	8.11959e-09 (rank : 194)
Query Neighborhood Hits	498	Target Neighborhood Hits	435	Shared Neighborhood Hits	302
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

PP16A_HUMAN
NC score	0.800444 (rank : 90)	θ value	7.84624e-12 (rank : 144)
Query Neighborhood Hits	498	Target Neighborhood Hits	340	Shared Neighborhood Hits	281
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANKS6_HUMAN
NC score	0.800389 (rank : 91)	θ value	3.64472e-09 (rank : 186)
Query Neighborhood Hits	498	Target Neighborhood Hits	411	Shared Neighborhood Hits	306
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB5_MOUSE
NC score	0.800005 (rank : 92)	θ value	2.60593e-15 (rank : 77)
Query Neighborhood Hits	498	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR22_HUMAN
NC score	0.799125 (rank : 93)	θ value	2.79066e-09 (rank : 182)
Query Neighborhood Hits	498	Target Neighborhood Hits	243	Shared Neighborhood Hits	243
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB15_MOUSE
NC score	0.796792 (rank : 94)	θ value	1.86753e-13 (rank : 104)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB9_MOUSE
NC score	0.795928 (rank : 95)	θ value	6.41864e-14 (rank : 99)
Query Neighborhood Hits	498	Target Neighborhood Hits	257	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB14_MOUSE
NC score	0.795521 (rank : 96)	θ value	5.08577e-11 (rank : 153)
Query Neighborhood Hits	498	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

PP16B_HUMAN
NC score	0.794841 (rank : 97)	θ value	3.52202e-12 (rank : 134)
Query Neighborhood Hits	498	Target Neighborhood Hits	307	Shared Neighborhood Hits	284
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PP16B_MOUSE
NC score	0.794762 (rank : 98)	θ value	4.16044e-13 (rank : 111)
Query Neighborhood Hits	498	Target Neighborhood Hits	302	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

MYPT2_HUMAN
NC score	0.791912 (rank : 99)	θ value	1.58096e-12 (rank : 124)
Query Neighborhood Hits	498	Target Neighborhood Hits	707	Shared Neighborhood Hits	321
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MYPT1_HUMAN
NC score	0.791781 (rank : 100)	θ value	4.44505e-15 (rank : 80)
Query Neighborhood Hits	498	Target Neighborhood Hits	723	Shared Neighborhood Hits	333
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CDN2D_HUMAN
NC score	0.791720 (rank : 101)	θ value	6.43352e-06 (rank : 231)
Query Neighborhood Hits	498	Target Neighborhood Hits	268	Shared Neighborhood Hits	267
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANKS1_MOUSE
NC score	0.790585 (rank : 102)	θ value	7.58209e-15 (rank : 81)
Query Neighborhood Hits	498	Target Neighborhood Hits	453	Shared Neighborhood Hits	300
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ASB4_HUMAN
NC score	0.787943 (rank : 103)	θ value	8.67504e-11 (rank : 159)
Query Neighborhood Hits	498	Target Neighborhood Hits	264	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
NC score	0.786963 (rank : 104)	θ value	1.133e-10 (rank : 160)
Query Neighborhood Hits	498	Target Neighborhood Hits	265	Shared Neighborhood Hits	260
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

RN5A_HUMAN
NC score	0.786463 (rank : 105)	θ value	3.52202e-12 (rank : 135)
Query Neighborhood Hits	498	Target Neighborhood Hits	608	Shared Neighborhood Hits	288
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANK2_HUMAN
NC score	0.785953 (rank : 106)	θ value	1.5242e-23 (rank : 22)
Query Neighborhood Hits	498	Target Neighborhood Hits	1615	Shared Neighborhood Hits	369
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

IKBA_HUMAN
NC score	0.784886 (rank : 107)	θ value	3.08544e-08 (rank : 206)
Query Neighborhood Hits	498	Target Neighborhood Hits	280	Shared Neighborhood Hits	276
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ACBD6_MOUSE
NC score	0.784434 (rank : 108)	θ value	4.76016e-09 (rank : 190)
Query Neighborhood Hits	498	Target Neighborhood Hits	305	Shared Neighborhood Hits	291
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

CSKI2_HUMAN
NC score	0.784098 (rank : 109)	θ value	4.91457e-14 (rank : 97)
Query Neighborhood Hits	498	Target Neighborhood Hits	747	Shared Neighborhood Hits	316
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB1_HUMAN
NC score	0.782379 (rank : 110)	θ value	1.80886e-08 (rank : 198)
Query Neighborhood Hits	498	Target Neighborhood Hits	291	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CSKI2_MOUSE
NC score	0.781479 (rank : 111)	θ value	4.91457e-14 (rank : 98)
Query Neighborhood Hits	498	Target Neighborhood Hits	812	Shared Neighborhood Hits	311
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR46_HUMAN
NC score	0.781282 (rank : 112)	θ value	1.09739e-05 (rank : 232)
Query Neighborhood Hits	498	Target Neighborhood Hits	281	Shared Neighborhood Hits	274
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CDN2D_MOUSE
NC score	0.780813 (rank : 113)	θ value	0.000270298 (rank : 260)
Query Neighborhood Hits	498	Target Neighborhood Hits	267	Shared Neighborhood Hits	265
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ACBD6_HUMAN
NC score	0.780315 (rank : 114)	θ value	1.38499e-08 (rank : 195)
Query Neighborhood Hits	498	Target Neighborhood Hits	304	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB12_HUMAN
NC score	0.779373 (rank : 115)	θ value	2.36244e-08 (rank : 202)
Query Neighborhood Hits	498	Target Neighborhood Hits	263	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

IKBE_MOUSE
NC score	0.778807 (rank : 116)	θ value	1.80886e-08 (rank : 199)
Query Neighborhood Hits	498	Target Neighborhood Hits	308	Shared Neighborhood Hits	282
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

CSKI1_HUMAN
NC score	0.778769 (rank : 117)	θ value	3.40345e-15 (rank : 79)
Query Neighborhood Hits	498	Target Neighborhood Hits	997	Shared Neighborhood Hits	321
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
NC score	0.778664 (rank : 118)	θ value	1.99529e-15 (rank : 73)
Query Neighborhood Hits	498	Target Neighborhood Hits	1031	Shared Neighborhood Hits	326
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB1_MOUSE
NC score	0.778467 (rank : 119)	θ value	5.26297e-08 (rank : 208)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR35_HUMAN
NC score	0.777348 (rank : 120)	θ value	6.20254e-17 (rank : 53)
Query Neighborhood Hits	498	Target Neighborhood Hits	784	Shared Neighborhood Hits	306
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB12_MOUSE
NC score	0.776676 (rank : 121)	θ value	3.64472e-09 (rank : 188)
Query Neighborhood Hits	498	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

POTE8_HUMAN
NC score	0.775430 (rank : 122)	θ value	1.99529e-15 (rank : 74)
Query Neighborhood Hits	498	Target Neighborhood Hits	337	Shared Neighborhood Hits	294
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

CT086_HUMAN
NC score	0.774808 (rank : 123)	θ value	0.00869519 (rank : 287)
Query Neighborhood Hits	498	Target Neighborhood Hits	277	Shared Neighborhood Hits	271
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR46_MOUSE
NC score	0.773946 (rank : 124)	θ value	4.1701e-05 (rank : 244)
Query Neighborhood Hits	498	Target Neighborhood Hits	274	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

BARD1_HUMAN
NC score	0.773930 (rank : 125)	θ value	5.08577e-11 (rank : 154)
Query Neighborhood Hits	498	Target Neighborhood Hits	427	Shared Neighborhood Hits	292
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

AN36A_HUMAN
NC score	0.773738 (rank : 126)	θ value	1.47974e-10 (rank : 162)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

BARD1_MOUSE
NC score	0.772983 (rank : 127)	θ value	1.133e-10 (rank : 161)
Query Neighborhood Hits	498	Target Neighborhood Hits	411	Shared Neighborhood Hits	283
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBA_MOUSE
NC score	0.772319 (rank : 128)	θ value	5.81887e-07 (rank : 215)
Query Neighborhood Hits	498	Target Neighborhood Hits	283	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR19_HUMAN
NC score	0.769666 (rank : 129)	θ value	1.74796e-11 (rank : 147)
Query Neighborhood Hits	498	Target Neighborhood Hits	276	Shared Neighborhood Hits	273
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ZDH17_HUMAN
NC score	0.759312 (rank : 130)	θ value	1.86321e-21 (rank : 30)
Query Neighborhood Hits	498	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

IKBE_HUMAN
NC score	0.758370 (rank : 131)	θ value	1.99992e-07 (rank : 210)
Query Neighborhood Hits	498	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

USH1G_MOUSE
NC score	0.757678 (rank : 132)	θ value	6.64225e-11 (rank : 158)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.757512 (rank : 133)	θ value	6.64225e-11 (rank : 157)
Query Neighborhood Hits	498	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ZDH17_MOUSE
NC score	0.754702 (rank : 134)	θ value	4.15078e-21 (rank : 31)
Query Neighborhood Hits	498	Target Neighborhood Hits	328	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANS4B_HUMAN
NC score	0.752926 (rank : 135)	θ value	1.25267e-09 (rank : 173)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANKY2_HUMAN
NC score	0.747005 (rank : 136)	θ value	2.79066e-09 (rank : 180)
Query Neighborhood Hits	498	Target Neighborhood Hits	306	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ZDH13_HUMAN
NC score	0.745954 (rank : 137)	θ value	8.95645e-16 (rank : 69)
Query Neighborhood Hits	498	Target Neighborhood Hits	322	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

RN5A_MOUSE
NC score	0.743945 (rank : 138)	θ value	2.13179e-17 (rank : 52)
Query Neighborhood Hits	498	Target Neighborhood Hits	899	Shared Neighborhood Hits	299
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ZDH13_MOUSE
NC score	0.743225 (rank : 139)	θ value	2.60593e-15 (rank : 78)
Query Neighborhood Hits	498	Target Neighborhood Hits	329	Shared Neighborhood Hits	282
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANFY1_MOUSE
NC score	0.741477 (rank : 140)	θ value	2.43908e-13 (rank : 105)
Query Neighborhood Hits	498	Target Neighborhood Hits	480	Shared Neighborhood Hits	300
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANS4B_MOUSE
NC score	0.741246 (rank : 141)	θ value	2.36244e-08 (rank : 201)
Query Neighborhood Hits	498	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANFY1_HUMAN
NC score	0.739538 (rank : 142)	θ value	1.2105e-12 (rank : 122)
Query Neighborhood Hits	498	Target Neighborhood Hits	480	Shared Neighborhood Hits	293
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR32_HUMAN
NC score	0.736120 (rank : 143)	θ value	3.77169e-06 (rank : 226)
Query Neighborhood Hits	498	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBB_MOUSE
NC score	0.733081 (rank : 144)	θ value	0.000461057 (rank : 264)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

IKBB_HUMAN
NC score	0.732644 (rank : 145)	θ value	0.000270298 (rank : 261)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANR11_HUMAN
NC score	0.729406 (rank : 146)	θ value	1.63604e-09 (rank : 175)
Query Neighborhood Hits	498	Target Neighborhood Hits	1289	Shared Neighborhood Hits	349
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

POT15_HUMAN
NC score	0.729122 (rank : 147)	θ value	2.35696e-16 (rank : 63)
Query Neighborhood Hits	498	Target Neighborhood Hits	893	Shared Neighborhood Hits	312
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR32_MOUSE
NC score	0.728990 (rank : 148)	θ value	2.88788e-06 (rank : 224)
Query Neighborhood Hits	498	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR21_HUMAN
NC score	0.728661 (rank : 149)	θ value	6.85773e-16 (rank : 66)
Query Neighborhood Hits	498	Target Neighborhood Hits	864	Shared Neighborhood Hits	313
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CTTB2_HUMAN
NC score	0.727546 (rank : 150)	θ value	1.38178e-16 (rank : 57)
Query Neighborhood Hits	498	Target Neighborhood Hits	1061	Shared Neighborhood Hits	326
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANKY2_MOUSE
NC score	0.720020 (rank : 151)	θ value	2.79066e-09 (rank : 181)
Query Neighborhood Hits	498	Target Neighborhood Hits	316	Shared Neighborhood Hits	265
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB6_HUMAN
NC score	0.712979 (rank : 152)	θ value	1.87187e-05 (rank : 237)
Query Neighborhood Hits	498	Target Neighborhood Hits	256	Shared Neighborhood Hits	247
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR15_HUMAN
NC score	0.712859 (rank : 153)	θ value	2.36244e-08 (rank : 200)
Query Neighborhood Hits	498	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ASB6_MOUSE
NC score	0.709735 (rank : 154)	θ value	1.87187e-05 (rank : 238)
Query Neighborhood Hits	498	Target Neighborhood Hits	264	Shared Neighborhood Hits	245
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR37_HUMAN
NC score	0.705087 (rank : 155)	θ value	0.000786445 (rank : 271)
Query Neighborhood Hits	498	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

POT14_HUMAN
NC score	0.705057 (rank : 156)	θ value	7.59969e-07 (rank : 217)
Query Neighborhood Hits	498	Target Neighborhood Hits	403	Shared Neighborhood Hits	284
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR47_MOUSE
NC score	0.704545 (rank : 157)	θ value	5.81887e-07 (rank : 214)
Query Neighborhood Hits	498	Target Neighborhood Hits	350	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR41_HUMAN
NC score	0.702148 (rank : 158)	θ value	0.365318 (rank : 329)
Query Neighborhood Hits	498	Target Neighborhood Hits	332	Shared Neighborhood Hits	261
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

SHAN1_HUMAN
NC score	0.701648 (rank : 159)	θ value	1.80466e-16 (rank : 62)
Query Neighborhood Hits	498	Target Neighborhood Hits	1041	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR12_HUMAN
NC score	0.700527 (rank : 160)	θ value	6.64225e-11 (rank : 156)
Query Neighborhood Hits	498	Target Neighborhood Hits	1081	Shared Neighborhood Hits	332
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

NFKB2_HUMAN
NC score	0.696714 (rank : 161)	θ value	9.59137e-10 (rank : 172)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	281
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

SNCAP_HUMAN
NC score	0.695807 (rank : 162)	θ value	9.92553e-07 (rank : 219)
Query Neighborhood Hits	498	Target Neighborhood Hits	313	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

CLPB_MOUSE
NC score	0.694741 (rank : 163)	θ value	1.47974e-10 (rank : 163)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	254
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

NFKB1_MOUSE
NC score	0.694097 (rank : 164)	θ value	2.13673e-09 (rank : 178)
Query Neighborhood Hits	498	Target Neighborhood Hits	300	Shared Neighborhood Hits	272
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB1_HUMAN
NC score	0.693896 (rank : 165)	θ value	1.38499e-08 (rank : 197)
Query Neighborhood Hits	498	Target Neighborhood Hits	306	Shared Neighborhood Hits	279
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR47_HUMAN
NC score	0.691685 (rank : 166)	θ value	6.21693e-09 (rank : 191)
Query Neighborhood Hits	498	Target Neighborhood Hits	369	Shared Neighborhood Hits	263
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR37_MOUSE
NC score	0.686889 (rank : 167)	θ value	0.000461057 (rank : 263)
Query Neighborhood Hits	498	Target Neighborhood Hits	237	Shared Neighborhood Hits	237
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

BCOR_MOUSE
NC score	0.683063 (rank : 168)	θ value	1.09739e-05 (rank : 233)
Query Neighborhood Hits	498	Target Neighborhood Hits	521	Shared Neighborhood Hits	293
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

MPP8_HUMAN
NC score	0.681062 (rank : 169)	θ value	7.09661e-13 (rank : 116)
Query Neighborhood Hits	498	Target Neighborhood Hits	948	Shared Neighborhood Hits	302
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NFKB2_MOUSE
NC score	0.679296 (rank : 170)	θ value	3.64472e-09 (rank : 189)
Query Neighborhood Hits	498	Target Neighborhood Hits	326	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR33_MOUSE
NC score	0.676734 (rank : 171)	θ value	5.44631e-05 (rank : 246)
Query Neighborhood Hits	498	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BCOR_HUMAN
NC score	0.674395 (rank : 172)	θ value	2.44474e-05 (rank : 240)
Query Neighborhood Hits	498	Target Neighborhood Hits	609	Shared Neighborhood Hits	289
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD2A1_MOUSE
NC score	0.673815 (rank : 173)	θ value	7.1131e-05 (rank : 252)
Query Neighborhood Hits	498	Target Neighborhood Hits	206	Shared Neighborhood Hits	202
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

POT22_HUMAN
NC score	0.670314 (rank : 174)	θ value	9.92553e-07 (rank : 218)
Query Neighborhood Hits	498	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR33_HUMAN
NC score	0.670096 (rank : 175)	θ value	0.00020696 (rank : 255)
Query Neighborhood Hits	498	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

A20A3_HUMAN
NC score	0.667957 (rank : 176)	θ value	6.00763e-12 (rank : 137)
Query Neighborhood Hits	498	Target Neighborhood Hits	692	Shared Neighborhood Hits	288
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.667150 (rank : 177)	θ value	1.33837e-11 (rank : 146)
Query Neighborhood Hits	498	Target Neighborhood Hits	716	Shared Neighborhood Hits	291
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.665788 (rank : 178)	θ value	1.33837e-11 (rank : 145)
Query Neighborhood Hits	498	Target Neighborhood Hits	698	Shared Neighborhood Hits	285
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A4_HUMAN
NC score	0.663177 (rank : 179)	θ value	6.00763e-12 (rank : 138)
Query Neighborhood Hits	498	Target Neighborhood Hits	710	Shared Neighborhood Hits	289
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

KRIT1_MOUSE
NC score	0.662208 (rank : 180)	θ value	3.77169e-06 (rank : 227)
Query Neighborhood Hits	498	Target Neighborhood Hits	258	Shared Neighborhood Hits	231
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ANR25_HUMAN
NC score	0.658341 (rank : 181)	θ value	1.43324e-05 (rank : 236)
Query Neighborhood Hits	498	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

KRIT1_HUMAN
NC score	0.651485 (rank : 182)	θ value	2.44474e-05 (rank : 243)
Query Neighborhood Hits	498	Target Neighborhood Hits	258	Shared Neighborhood Hits	227
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR25_MOUSE
NC score	0.648240 (rank : 183)	θ value	3.77169e-06 (rank : 225)
Query Neighborhood Hits	498	Target Neighborhood Hits	398	Shared Neighborhood Hits	266
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

OSBL1_HUMAN
NC score	0.646123 (rank : 184)	θ value	3.29651e-10 (rank : 168)
Query Neighborhood Hits	498	Target Neighborhood Hits	368	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR38_HUMAN
NC score	0.644824 (rank : 185)	θ value	1.69304e-06 (rank : 223)
Query Neighborhood Hits	498	Target Neighborhood Hits	443	Shared Neighborhood Hits	245
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSTF1_MOUSE
NC score	0.637119 (rank : 186)	θ value	2.36244e-08 (rank : 205)
Query Neighborhood Hits	498	Target Neighborhood Hits	467	Shared Neighborhood Hits	256
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OSBL1_MOUSE
NC score	0.635114 (rank : 187)	θ value	1.9326e-10 (rank : 164)
Query Neighborhood Hits	498	Target Neighborhood Hits	336	Shared Neighborhood Hits	285
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

CDN2B_MOUSE
NC score	0.635072 (rank : 188)	θ value	0.00020696 (rank : 256)
Query Neighborhood Hits	498	Target Neighborhood Hits	201	Shared Neighborhood Hits	198
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

RAI14_HUMAN
NC score	0.627691 (rank : 189)	θ value	5.60996e-18 (rank : 46)
Query Neighborhood Hits	498	Target Neighborhood Hits	1367	Shared Neighborhood Hits	332
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR38_MOUSE
NC score	0.624168 (rank : 190)	θ value	1.29631e-06 (rank : 221)
Query Neighborhood Hits	498	Target Neighborhood Hits	512	Shared Neighborhood Hits	248
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSTF1_HUMAN
NC score	0.621884 (rank : 191)	θ value	6.21693e-09 (rank : 193)
Query Neighborhood Hits	498	Target Neighborhood Hits	466	Shared Neighborhood Hits	254
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR18_HUMAN
NC score	0.614476 (rank : 192)	θ value	3.89403e-11 (rank : 151)
Query Neighborhood Hits	498	Target Neighborhood Hits	1106	Shared Neighborhood Hits	300
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CLPB_HUMAN
NC score	0.606483 (rank : 193)	θ value	2.61198e-07 (rank : 213)
Query Neighborhood Hits	498	Target Neighborhood Hits	265	Shared Neighborhood Hits	241
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR43_HUMAN
NC score	0.598529 (rank : 194)	θ value	7.1131e-05 (rank : 249)
Query Neighborhood Hits	498	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
NC score	0.597481 (rank : 195)	θ value	0.000602161 (rank : 266)
Query Neighborhood Hits	498	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

RAI14_MOUSE
NC score	0.596048 (rank : 196)	θ value	1.92812e-18 (rank : 43)
Query Neighborhood Hits	498	Target Neighborhood Hits	1505	Shared Neighborhood Hits	335
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CD2A1_HUMAN
NC score	0.596020 (rank : 197)	θ value	0.00175202 (rank : 279)
Query Neighborhood Hits	498	Target Neighborhood Hits	196	Shared Neighborhood Hits	192
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR43_MOUSE
NC score	0.594172 (rank : 198)	θ value	7.1131e-05 (rank : 250)
Query Neighborhood Hits	498	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

AN30A_HUMAN
NC score	0.588254 (rank : 199)	θ value	8.38298e-14 (rank : 100)
Query Neighborhood Hits	498	Target Neighborhood Hits	1119	Shared Neighborhood Hits	314
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR40_HUMAN
NC score	0.584226 (rank : 200)	θ value	0.000270298 (rank : 258)
Query Neighborhood Hits	498	Target Neighborhood Hits	224	Shared Neighborhood Hits	202
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
NC score	0.583223 (rank : 201)	θ value	0.000270298 (rank : 259)
Query Neighborhood Hits	498	Target Neighborhood Hits	228	Shared Neighborhood Hits	206
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

HECD1_HUMAN
NC score	0.580843 (rank : 202)	θ value	4.1701e-05 (rank : 245)
Query Neighborhood Hits	498	Target Neighborhood Hits	371	Shared Neighborhood Hits	272
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

NUD12_MOUSE
NC score	0.577660 (rank : 203)	θ value	1.99992e-07 (rank : 211)
Query Neighborhood Hits	498	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ABTB2_HUMAN
NC score	0.572543 (rank : 204)	θ value	1.29631e-06 (rank : 220)
Query Neighborhood Hits	498	Target Neighborhood Hits	391	Shared Neighborhood Hits	239
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR45_MOUSE
NC score	0.561851 (rank : 205)	θ value	0.62314 (rank : 350)
Query Neighborhood Hits	498	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ABTB2_MOUSE
NC score	0.560157 (rank : 206)	θ value	4.92598e-06 (rank : 228)
Query Neighborhood Hits	498	Target Neighborhood Hits	414	Shared Neighborhood Hits	240
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
NC score	0.557716 (rank : 207)	θ value	1.38499e-08 (rank : 196)
Query Neighborhood Hits	498	Target Neighborhood Hits	1156	Shared Neighborhood Hits	303
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

IASPP_HUMAN
NC score	0.550619 (rank : 208)	θ value	1.29631e-06 (rank : 222)
Query Neighborhood Hits	498	Target Neighborhood Hits	688	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANKK1_HUMAN
NC score	0.547162 (rank : 209)	θ value	1.5242e-23 (rank : 23)
Query Neighborhood Hits	498	Target Neighborhood Hits	1075	Shared Neighborhood Hits	303
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

NUD12_HUMAN
NC score	0.544063 (rank : 210)	θ value	1.09739e-05 (rank : 234)
Query Neighborhood Hits	498	Target Neighborhood Hits	222	Shared Neighborhood Hits	203
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CENB5_HUMAN
NC score	0.542897 (rank : 211)	θ value	2.61198e-07 (rank : 212)
Query Neighborhood Hits	498	Target Neighborhood Hits	395	Shared Neighborhood Hits	264
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.542177 (rank : 212)	θ value	8.97725e-08 (rank : 209)
Query Neighborhood Hits	498	Target Neighborhood Hits	383	Shared Neighborhood Hits	257
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ASB14_HUMAN
NC score	0.539117 (rank : 213)	θ value	7.1131e-05 (rank : 251)
Query Neighborhood Hits	498	Target Neighborhood Hits	187	Shared Neighborhood Hits	174
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASPP1_HUMAN
NC score	0.538584 (rank : 214)	θ value	6.43352e-06 (rank : 229)
Query Neighborhood Hits	498	Target Neighborhood Hits	956	Shared Neighborhood Hits	294
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TRPV6_MOUSE
NC score	0.537629 (rank : 215)	θ value	1.09739e-05 (rank : 235)
Query Neighborhood Hits	498	Target Neighborhood Hits	284	Shared Neighborhood Hits	257
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

CENB2_HUMAN
NC score	0.537176 (rank : 216)	θ value	2.28291e-11 (rank : 150)
Query Neighborhood Hits	498	Target Neighborhood Hits	425	Shared Neighborhood Hits	258
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

RIPK4_HUMAN
NC score	0.536647 (rank : 217)	θ value	6.84181e-24 (rank : 20)
Query Neighborhood Hits	498	Target Neighborhood Hits	1094	Shared Neighborhood Hits	309
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_MOUSE
NC score	0.531776 (rank : 218)	θ value	1.6852e-22 (rank : 27)
Query Neighborhood Hits	498	Target Neighborhood Hits	1072	Shared Neighborhood Hits	301
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR45_HUMAN
NC score	0.527137 (rank : 219)	θ value	1.38821 (rank : 368)
Query Neighborhood Hits	498	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASPP1_MOUSE
NC score	0.526208 (rank : 220)	θ value	6.43352e-06 (rank : 230)
Query Neighborhood Hits	498	Target Neighborhood Hits	1244	Shared Neighborhood Hits	302
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ANKY1_HUMAN
NC score	0.521412 (rank : 221)	θ value	0.0431538 (rank : 299)
Query Neighborhood Hits	498	Target Neighborhood Hits	248	Shared Neighborhood Hits	207
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ILK2_HUMAN
NC score	0.514331 (rank : 222)	θ value	2.0648e-12 (rank : 127)
Query Neighborhood Hits	498	Target Neighborhood Hits	848	Shared Neighborhood Hits	285
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

AN13B_MOUSE
NC score	0.505412 (rank : 223)	θ value	0.00509761 (rank : 283)
Query Neighborhood Hits	498	Target Neighborhood Hits	276	Shared Neighborhood Hits	256
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.504640 (rank : 224)	θ value	0.00509761 (rank : 282)
Query Neighborhood Hits	498	Target Neighborhood Hits	265	Shared Neighborhood Hits	254
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

IASPP_MOUSE
NC score	0.502162 (rank : 225)	θ value	7.59969e-07 (rank : 216)
Query Neighborhood Hits	498	Target Neighborhood Hits	1024	Shared Neighborhood Hits	283
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GIT2_MOUSE
NC score	0.499537 (rank : 226)	θ value	0.000602161 (rank : 269)
Query Neighborhood Hits	498	Target Neighborhood Hits	323	Shared Neighborhood Hits	254
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GLSL_HUMAN
NC score	0.498115 (rank : 227)	θ value	0.000602161 (rank : 270)
Query Neighborhood Hits	498	Target Neighborhood Hits	211	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ILK1_HUMAN
NC score	0.496715 (rank : 228)	θ value	2.0648e-12 (rank : 126)
Query Neighborhood Hits	498	Target Neighborhood Hits	857	Shared Neighborhood Hits	285
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.494920 (rank : 229)	θ value	4.59992e-12 (rank : 136)
Query Neighborhood Hits	498	Target Neighborhood Hits	858	Shared Neighborhood Hits	285
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

UACA_HUMAN
NC score	0.494739 (rank : 230)	θ value	1.9326e-10 (rank : 165)
Query Neighborhood Hits	498	Target Neighborhood Hits	1622	Shared Neighborhood Hits	335
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AN13C_HUMAN
NC score	0.493329 (rank : 231)	θ value	0.0563607 (rank : 304)
Query Neighborhood Hits	498	Target Neighborhood Hits	241	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT1_MOUSE
NC score	0.483722 (rank : 232)	θ value	0.000786445 (rank : 274)
Query Neighborhood Hits	498	Target Neighborhood Hits	341	Shared Neighborhood Hits	250
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.483057 (rank : 233)	θ value	0.000786445 (rank : 273)
Query Neighborhood Hits	498	Target Neighborhood Hits	336	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

TRPV5_MOUSE
NC score	0.482999 (rank : 234)	θ value	0.00020696 (rank : 257)
Query Neighborhood Hits	498	Target Neighborhood Hits	278	Shared Neighborhood Hits	250
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

GLSL_MOUSE
NC score	0.482480 (rank : 235)	θ value	0.0252991 (rank : 294)
Query Neighborhood Hits	498	Target Neighborhood Hits	212	Shared Neighborhood Hits	203
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13C_MOUSE
NC score	0.481841 (rank : 236)	θ value	0.125558 (rank : 314)
Query Neighborhood Hits	498	Target Neighborhood Hits	242	Shared Neighborhood Hits	234
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

UACA_MOUSE
NC score	0.469233 (rank : 237)	θ value	1.63604e-09 (rank : 176)
Query Neighborhood Hits	498	Target Neighborhood Hits	1620	Shared Neighborhood Hits	332
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GIT2_HUMAN
NC score	0.462475 (rank : 238)	θ value	0.00134147 (rank : 277)
Query Neighborhood Hits	498	Target Neighborhood Hits	381	Shared Neighborhood Hits	250
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

NOTC4_MOUSE
NC score	0.461904 (rank : 239)	θ value	1.63225e-17 (rank : 51)
Query Neighborhood Hits	498	Target Neighborhood Hits	872	Shared Neighborhood Hits	299
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR26_MOUSE
NC score	0.459648 (rank : 240)	θ value	2.13673e-09 (rank : 177)
Query Neighborhood Hits	498	Target Neighborhood Hits	1554	Shared Neighborhood Hits	328
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC4_HUMAN
NC score	0.457029 (rank : 241)	θ value	2.97466e-19 (rank : 38)
Query Neighborhood Hits	498	Target Neighborhood Hits	905	Shared Neighborhood Hits	306
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV5_HUMAN
NC score	0.456337 (rank : 242)	θ value	5.44631e-05 (rank : 247)
Query Neighborhood Hits	498	Target Neighborhood Hits	261	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

CT012_MOUSE
NC score	0.454439 (rank : 243)	θ value	0.000158464 (rank : 254)
Query Neighborhood Hits	498	Target Neighborhood Hits	229	Shared Neighborhood Hits	180
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

TRPV6_HUMAN
NC score	0.453530 (rank : 244)	θ value	0.000270298 (rank : 262)
Query Neighborhood Hits	498	Target Neighborhood Hits	262	Shared Neighborhood Hits	229
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

DDFL1_MOUSE
NC score	0.449812 (rank : 245)	θ value	0.000602161 (rank : 268)
Query Neighborhood Hits	498	Target Neighborhood Hits	324	Shared Neighborhood Hits	250
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GLSK_HUMAN
NC score	0.446208 (rank : 246)	θ value	0.813845 (rank : 358)
Query Neighborhood Hits	498	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

ANR26_HUMAN
NC score	0.441889 (rank : 247)	θ value	3.64472e-09 (rank : 187)
Query Neighborhood Hits	498	Target Neighborhood Hits	1614	Shared Neighborhood Hits	336
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_HUMAN
NC score	0.439423 (rank : 248)	θ value	7.1131e-05 (rank : 248)
Query Neighborhood Hits	498	Target Neighborhood Hits	243	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

TNI3K_HUMAN
NC score	0.426677 (rank : 249)	θ value	8.65492e-19 (rank : 40)
Query Neighborhood Hits	498	Target Neighborhood Hits	1084	Shared Neighborhood Hits	300
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

SUV91_HUMAN
NC score	0.422947 (rank : 250)	θ value	4.13158e-37 (rank : 6)
Query Neighborhood Hits	498	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

TNI3K_MOUSE
NC score	0.419986 (rank : 251)	θ value	9.90251e-15 (rank : 86)
Query Neighborhood Hits	498	Target Neighborhood Hits	1079	Shared Neighborhood Hits	301
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

SUV91_MOUSE
NC score	0.419584 (rank : 252)	θ value	4.568e-36 (rank : 7)
Query Neighborhood Hits	498	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.418616 (rank : 253)	θ value	1.08726e-37 (rank : 5)
Query Neighborhood Hits	498	Target Neighborhood Hits	54	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

NOTC3_MOUSE
NC score	0.417976 (rank : 254)	θ value	2.88119e-14 (rank : 92)
Query Neighborhood Hits	498	Target Neighborhood Hits	975	Shared Neighborhood Hits	306
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SUV92_MOUSE
NC score	0.416599 (rank : 255)	θ value	8.32485e-38 (rank : 4)
Query Neighborhood Hits	498	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

NOTC3_HUMAN
NC score	0.415745 (rank : 256)	θ value	3.76295e-14 (rank : 95)
Query Neighborhood Hits	498	Target Neighborhood Hits	1062	Shared Neighborhood Hits	308
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.414813 (rank : 257)	θ value	7.58209e-15 (rank : 82)
Query Neighborhood Hits	498	Target Neighborhood Hits	1113	Shared Neighborhood Hits	311
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CT012_HUMAN
NC score	0.414452 (rank : 258)	θ value	0.00869519 (rank : 286)
Query Neighborhood Hits	498	Target Neighborhood Hits	205	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

NOTC1_HUMAN
NC score	0.413247 (rank : 259)	θ value	5.43371e-13 (rank : 113)
Query Neighborhood Hits	498	Target Neighborhood Hits	906	Shared Neighborhood Hits	298
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.411629 (rank : 260)	θ value	7.58209e-15 (rank : 83)
Query Neighborhood Hits	498	Target Neighborhood Hits	1069	Shared Neighborhood Hits	307
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AN13A_MOUSE
NC score	0.411289 (rank : 261)	θ value	0.00228821 (rank : 280)
Query Neighborhood Hits	498	Target Neighborhood Hits	226	Shared Neighborhood Hits	217
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

DAPK1_MOUSE
NC score	0.387554 (rank : 262)	θ value	8.93572e-24 (rank : 21)
Query Neighborhood Hits	498	Target Neighborhood Hits	1138	Shared Neighborhood Hits	300
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DDEF2_HUMAN
NC score	0.382013 (rank : 263)	θ value	0.00869519 (rank : 288)
Query Neighborhood Hits	498	Target Neighborhood Hits	599	Shared Neighborhood Hits	242
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.379019 (rank : 264)	θ value	0.00869519 (rank : 289)
Query Neighborhood Hits	498	Target Neighborhood Hits	625	Shared Neighborhood Hits	247
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DAPK1_HUMAN
NC score	0.378571 (rank : 265)	θ value	1.42661e-21 (rank : 29)
Query Neighborhood Hits	498	Target Neighborhood Hits	1130	Shared Neighborhood Hits	298
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_MOUSE
NC score	0.376671 (rank : 266)	θ value	0.000786445 (rank : 276)
Query Neighborhood Hits	498	Target Neighborhood Hits	1333	Shared Neighborhood Hits	281
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DGKZ_HUMAN
NC score	0.373006 (rank : 267)	θ value	2.44474e-05 (rank : 241)
Query Neighborhood Hits	498	Target Neighborhood Hits	551	Shared Neighborhood Hits	219
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

TEX14_HUMAN
NC score	0.368562 (rank : 268)	θ value	0.125558 (rank : 317)
Query Neighborhood Hits	498	Target Neighborhood Hits	1103	Shared Neighborhood Hits	266
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDFL1_HUMAN
NC score	0.368047 (rank : 269)	θ value	0.0431538 (rank : 300)
Query Neighborhood Hits	498	Target Neighborhood Hits	353	Shared Neighborhood Hits	234
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

SETB2_HUMAN
NC score	0.367959 (rank : 270)	θ value	1.47631e-18 (rank : 42)
Query Neighborhood Hits	498	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.361204 (rank : 271)	θ value	1.05554e-24 (rank : 17)
Query Neighborhood Hits	498	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.356773 (rank : 272)	θ value	1.05554e-24 (rank : 16)
Query Neighborhood Hits	498	Target Neighborhood Hits	141	Shared Neighborhood Hits	32
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

CENG1_MOUSE
NC score	0.356354 (rank : 273)	θ value	0.000786445 (rank : 272)
Query Neighborhood Hits	498	Target Neighborhood Hits	531	Shared Neighborhood Hits	249
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DGKZ_MOUSE
NC score	0.355096 (rank : 274)	θ value	2.44474e-05 (rank : 242)
Query Neighborhood Hits	498	Target Neighborhood Hits	542	Shared Neighborhood Hits	206
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_HUMAN
NC score	0.353344 (rank : 275)	θ value	0.000602161 (rank : 267)
Query Neighborhood Hits	498	Target Neighborhood Hits	544	Shared Neighborhood Hits	247
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

NOTC1_MOUSE
NC score	0.353341 (rank : 276)	θ value	2.13673e-09 (rank : 179)
Query Neighborhood Hits	498	Target Neighborhood Hits	916	Shared Neighborhood Hits	278
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CENG2_HUMAN
NC score	0.347788 (rank : 277)	θ value	0.00509761 (rank : 284)
Query Neighborhood Hits	498	Target Neighborhood Hits	471	Shared Neighborhood Hits	255
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

SETD2_HUMAN
NC score	0.344780 (rank : 278)	θ value	7.32683e-18 (rank : 47)
Query Neighborhood Hits	498	Target Neighborhood Hits	412	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CENG2_MOUSE
NC score	0.344435 (rank : 279)	θ value	0.00869519 (rank : 285)
Query Neighborhood Hits	498	Target Neighborhood Hits	463	Shared Neighborhood Hits	250
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

EZH2_HUMAN
NC score	0.344295 (rank : 280)	θ value	1.63225e-17 (rank : 50)
Query Neighborhood Hits	498	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_HUMAN
NC score	0.343227 (rank : 281)	θ value	1.24977e-17 (rank : 49)
Query Neighborhood Hits	498	Target Neighborhood Hits	121	Shared Neighborhood Hits	34
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.342731 (rank : 282)	θ value	9.56915e-18 (rank : 48)
Query Neighborhood Hits	498	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_MOUSE
NC score	0.341037 (rank : 283)	θ value	8.10077e-17 (rank : 55)
Query Neighborhood Hits	498	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

DGKI_HUMAN
NC score	0.337923 (rank : 284)	θ value	0.00390308 (rank : 281)
Query Neighborhood Hits	498	Target Neighborhood Hits	609	Shared Neighborhood Hits	219
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

IKBL_HUMAN
NC score	0.326466 (rank : 285)	θ value	0.365318 (rank : 332)
Query Neighborhood Hits	498	Target Neighborhood Hits	168	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.322014 (rank : 286)	θ value	0.125558 (rank : 315)
Query Neighborhood Hits	498	Target Neighborhood Hits	196	Shared Neighborhood Hits	143
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CLR59_HUMAN
NC score	0.317042 (rank : 287)	θ value	1.87187e-05 (rank : 239)
Query Neighborhood Hits	498	Target Neighborhood Hits	163	Shared Neighborhood Hits	142
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ANKZ1_MOUSE
NC score	0.316215 (rank : 288)	θ value	0.0736092 (rank : 310)
Query Neighborhood Hits	498	Target Neighborhood Hits	208	Shared Neighborhood Hits	154
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CENG3_MOUSE
NC score	0.316211 (rank : 289)	θ value	0.0113563 (rank : 292)
Query Neighborhood Hits	498	Target Neighborhood Hits	467	Shared Neighborhood Hits	232
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.315993 (rank : 290)	θ value	0.0113563 (rank : 291)
Query Neighborhood Hits	498	Target Neighborhood Hits	455	Shared Neighborhood Hits	230
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ABTB1_MOUSE
NC score	0.314924 (rank : 291)	θ value	0.00175202 (rank : 278)
Query Neighborhood Hits	498	Target Neighborhood Hits	349	Shared Neighborhood Hits	178
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

SET1A_HUMAN
NC score	0.308212 (rank : 292)	θ value	9.26847e-13 (rank : 121)
Query Neighborhood Hits	498	Target Neighborhood Hits	690	Shared Neighborhood Hits	84
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_MOUSE
NC score	0.296885 (rank : 293)	θ value	2.79066e-09 (rank : 185)
Query Neighborhood Hits	498	Target Neighborhood Hits	131	Shared Neighborhood Hits	30
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
NC score	0.293914 (rank : 294)	θ value	3.08544e-08 (rank : 207)
Query Neighborhood Hits	498	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

ANKZ1_HUMAN
NC score	0.289339 (rank : 295)	θ value	6.88961 (rank : 455)
Query Neighborhood Hits	498	Target Neighborhood Hits	236	Shared Neighborhood Hits	163
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

NSD1_MOUSE
NC score	0.287083 (rank : 296)	θ value	5.25075e-16 (rank : 64)
Query Neighborhood Hits	498	Target Neighborhood Hits	472	Shared Neighborhood Hits	51
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

DDEF1_MOUSE
NC score	0.285176 (rank : 297)	θ value	1.06291 (rank : 364)
Query Neighborhood Hits	498	Target Neighborhood Hits	592	Shared Neighborhood Hits	201
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NSD1_HUMAN
NC score	0.282578 (rank : 298)	θ value	6.85773e-16 (rank : 68)
Query Neighborhood Hits	498	Target Neighborhood Hits	427	Shared Neighborhood Hits	52
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ANKR9_MOUSE
NC score	0.273716 (rank : 299)	θ value	0.365318 (rank : 328)
Query Neighborhood Hits	498	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ABTB1_HUMAN
NC score	0.273595 (rank : 300)	θ value	0.0113563 (rank : 290)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

HRX_HUMAN
NC score	0.272659 (rank : 301)	θ value	2.43908e-13 (rank : 108)
Query Neighborhood Hits	498	Target Neighborhood Hits	825	Shared Neighborhood Hits	81
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

BAT4_MOUSE
NC score	0.271407 (rank : 302)	θ value	0.365318 (rank : 330)
Query Neighborhood Hits	498	Target Neighborhood Hits	171	Shared Neighborhood Hits	122
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

MLL4_HUMAN
NC score	0.259962 (rank : 303)	θ value	2.0648e-12 (rank : 128)
Query Neighborhood Hits	498	Target Neighborhood Hits	722	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

RSNL2_HUMAN
NC score	0.256036 (rank : 304)	θ value	0.000121331 (rank : 253)
Query Neighborhood Hits	498	Target Neighborhood Hits	136	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV3_MOUSE
NC score	0.236133 (rank : 305)	θ value	0.365318 (rank : 338)
Query Neighborhood Hits	498	Target Neighborhood Hits	188	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.233976 (rank : 306)	θ value	0.365318 (rank : 337)
Query Neighborhood Hits	498	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV1_MOUSE
NC score	0.231233 (rank : 307)	θ value	1.06291 (rank : 367)
Query Neighborhood Hits	498	Target Neighborhood Hits	189	Shared Neighborhood Hits	158
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

BAT4_HUMAN
NC score	0.230017 (rank : 308)	θ value	8.99809 (rank : 479)
Query Neighborhood Hits	498	Target Neighborhood Hits	157	Shared Neighborhood Hits	111
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

RSNL2_MOUSE
NC score	0.226171 (rank : 309)	θ value	0.000461057 (rank : 265)
Query Neighborhood Hits	498	Target Neighborhood Hits	129	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ANKR9_HUMAN
NC score	0.225844 (rank : 310)	θ value	0.813845 (rank : 355)
Query Neighborhood Hits	498	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TRPV1_HUMAN
NC score	0.221416 (rank : 311)	θ value	0.163984 (rank : 321)
Query Neighborhood Hits	498	Target Neighborhood Hits	184	Shared Neighborhood Hits	151
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

MLL3_MOUSE
NC score	0.211364 (rank : 312)	θ value	5.08577e-11 (rank : 155)
Query Neighborhood Hits	498	Target Neighborhood Hits	1399	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.207475 (rank : 313)	θ value	3.89403e-11 (rank : 152)
Query Neighborhood Hits	498	Target Neighborhood Hits	1788	Shared Neighborhood Hits	99
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.205839 (rank : 314)	θ value	1.74796e-11 (rank : 149)
Query Neighborhood Hits	498	Target Neighborhood Hits	1644	Shared Neighborhood Hits	118
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TRPV2_HUMAN
NC score	0.204103 (rank : 315)	θ value	0.163984 (rank : 322)
Query Neighborhood Hits	498	Target Neighborhood Hits	130	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CMTA1_HUMAN
NC score	0.173491 (rank : 316)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	498	Target Neighborhood Hits	217	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TRPV2_MOUSE
NC score	0.154627 (rank : 317)	θ value	3.0926 (rank : 411)
Query Neighborhood Hits	498	Target Neighborhood Hits	111	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CMTA2_HUMAN
NC score	0.134845 (rank : 318)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	498	Target Neighborhood Hits	199	Shared Neighborhood Hits	93
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ANKF1_HUMAN
NC score	0.128730 (rank : 319)	θ value	8.99809 (rank : 478)
Query Neighborhood Hits	498	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CMTA2_MOUSE
NC score	0.123254 (rank : 320)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	498	Target Neighborhood Hits	216	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPC6_HUMAN
NC score	0.123058 (rank : 321)	θ value	0.0252991 (rank : 295)
Query Neighborhood Hits	498	Target Neighborhood Hits	171	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPV4_HUMAN
NC score	0.122850 (rank : 322)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	498	Target Neighborhood Hits	150	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CU081_HUMAN
NC score	0.112898 (rank : 323)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	498	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

TRPV4_MOUSE
NC score	0.108966 (rank : 324)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	498	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC3_HUMAN
NC score	0.102774 (rank : 325)	θ value	0.0563607 (rank : 306)
Query Neighborhood Hits	498	Target Neighborhood Hits	137	Shared Neighborhood Hits	84
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.095052 (rank : 326)	θ value	0.163984 (rank : 320)
Query Neighborhood Hits	498	Target Neighborhood Hits	171	Shared Neighborhood Hits	92
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC3_MOUSE
NC score	0.093224 (rank : 327)	θ value	0.365318 (rank : 336)
Query Neighborhood Hits	498	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC7_MOUSE
NC score	0.085685 (rank : 328)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	498	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.085198 (rank : 329)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	498	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC4_HUMAN
NC score	0.080270 (rank : 330)	θ value	0.0563607 (rank : 307)
Query Neighborhood Hits	498	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.080269 (rank : 331)	θ value	0.0563607 (rank : 308)
Query Neighborhood Hits	498	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.079595 (rank : 332)	θ value	4.03905 (rank : 429)
Query Neighborhood Hits	498	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.078335 (rank : 333)	θ value	5.27518 (rank : 450)
Query Neighborhood Hits	498	Target Neighborhood Hits	122	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

LRRK1_MOUSE
NC score	0.076050 (rank : 334)	θ value	1.81305 (rank : 382)
Query Neighborhood Hits	498	Target Neighborhood Hits	1267	Shared Neighborhood Hits	126
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NASP_HUMAN
NC score	0.067890 (rank : 335)	θ value	0.0193708 (rank : 293)
Query Neighborhood Hits	498	Target Neighborhood Hits	709	Shared Neighborhood Hits	72
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

TRDN_HUMAN
NC score	0.067242 (rank : 336)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	498	Target Neighborhood Hits	542	Shared Neighborhood Hits	77
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

LCE1D_HUMAN
NC score	0.062318 (rank : 337)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	498	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

BASP_HUMAN
NC score	0.061602 (rank : 338)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	50
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SRRM1_MOUSE
NC score	0.059680 (rank : 339)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	498	Target Neighborhood Hits	966	Shared Neighborhood Hits	89
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

LCE1C_HUMAN
NC score	0.059237 (rank : 340)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	498	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

XRCC4_HUMAN
NC score	0.059186 (rank : 341)	θ value	0.0330416 (rank : 297)
Query Neighborhood Hits	498	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

AKA12_HUMAN
NC score	0.059147 (rank : 342)	θ value	0.0961366 (rank : 313)
Query Neighborhood Hits	498	Target Neighborhood Hits	825	Shared Neighborhood Hits	76
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

TXND2_HUMAN
NC score	0.059118 (rank : 343)	θ value	0.62314 (rank : 353)
Query Neighborhood Hits	498	Target Neighborhood Hits	793	Shared Neighborhood Hits	76
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SMP1L_MOUSE
NC score	0.058981 (rank : 344)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	498	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_MOUSE
NC score	0.058401 (rank : 345)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	498	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

TRPC1_HUMAN
NC score	0.058234 (rank : 346)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	498	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

BASP_MOUSE
NC score	0.057531 (rank : 347)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	498	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

LCE1B_HUMAN
NC score	0.057228 (rank : 348)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	498	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

IWS1_MOUSE
NC score	0.056542 (rank : 349)	θ value	2.36792 (rank : 395)
Query Neighborhood Hits	498	Target Neighborhood Hits	1258	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SMP1L_HUMAN
NC score	0.056366 (rank : 350)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	498	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SRRM2_HUMAN
NC score	0.056335 (rank : 351)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	498	Target Neighborhood Hits	1296	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CENA1_HUMAN
NC score	0.056261 (rank : 352)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	498	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SMAP1_HUMAN
NC score	0.056221 (rank : 353)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	498	Target Neighborhood Hits	98	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

LCE1E_HUMAN
NC score	0.056154 (rank : 354)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	498	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

SRRM1_HUMAN
NC score	0.054954 (rank : 355)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	498	Target Neighborhood Hits	690	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ARFG3_MOUSE
NC score	0.054183 (rank : 356)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	498	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

JAG2_MOUSE
NC score	0.054147 (rank : 357)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	498	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MDC1_HUMAN
NC score	0.053926 (rank : 358)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	498	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PTMA_HUMAN
NC score	0.053758 (rank : 359)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	498	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

VPS72_MOUSE
NC score	0.053648 (rank : 360)	θ value	0.0563607 (rank : 309)
Query Neighborhood Hits	498	Target Neighborhood Hits	286	Shared Neighborhood Hits	26
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

PININ_MOUSE
NC score	0.053529 (rank : 361)	θ value	0.47712 (rank : 348)
Query Neighborhood Hits	498	Target Neighborhood Hits	777	Shared Neighborhood Hits	79
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

JAG1_MOUSE
NC score	0.053291 (rank : 362)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	498	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.053275 (rank : 363)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	498	Target Neighborhood Hits	514	Shared Neighborhood Hits	22
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

ARFG3_HUMAN
NC score	0.053269 (rank : 364)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	498	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

TRPC1_MOUSE
NC score	0.053080 (rank : 365)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	498	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

PRP1_HUMAN
NC score	0.052978 (rank : 366)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	498	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

ARFG1_MOUSE
NC score	0.052976 (rank : 367)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	498	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

DNER_MOUSE
NC score	0.052875 (rank : 368)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	498	Target Neighborhood Hits	413	Shared Neighborhood Hits	20
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

JAG2_HUMAN
NC score	0.052774 (rank : 369)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	498	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

VPS72_HUMAN
NC score	0.052513 (rank : 370)	θ value	0.0431538 (rank : 302)
Query Neighborhood Hits	498	Target Neighborhood Hits	274	Shared Neighborhood Hits	25
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CENA2_MOUSE
NC score	0.052485 (rank : 371)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	498	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

DNER_HUMAN
NC score	0.052321 (rank : 372)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	498	Target Neighborhood Hits	460	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

IF2P_HUMAN
NC score	0.052042 (rank : 373)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	498	Target Neighborhood Hits	889	Shared Neighborhood Hits	105
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

RSF1_HUMAN
NC score	0.052029 (rank : 374)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	498	Target Neighborhood Hits	539	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CYLC1_HUMAN
NC score	0.051708 (rank : 375)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	498	Target Neighborhood Hits	408	Shared Neighborhood Hits	65
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CENA2_HUMAN
NC score	0.051707 (rank : 376)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	498	Target Neighborhood Hits	83	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

NACAM_MOUSE
NC score	0.051456 (rank : 377)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	498	Target Neighborhood Hits	1866	Shared Neighborhood Hits	102
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RAI1_MOUSE
NC score	0.051454 (rank : 378)	θ value	0.279714 (rank : 326)
Query Neighborhood Hits	498	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ARFG1_HUMAN
NC score	0.051370 (rank : 379)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	498	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

LRRK1_HUMAN
NC score	0.051176 (rank : 380)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	498	Target Neighborhood Hits	1237	Shared Neighborhood Hits	100
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

CRUM2_HUMAN
NC score	0.051082 (rank : 381)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	498	Target Neighborhood Hits	453	Shared Neighborhood Hits	20
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

SSB4_HUMAN
NC score	0.050970 (rank : 382)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	498	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

ARI4A_HUMAN
NC score	0.048692 (rank : 383)	θ value	1.06291 (rank : 362)
Query Neighborhood Hits	498	Target Neighborhood Hits	434	Shared Neighborhood Hits	56
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

PININ_HUMAN
NC score	0.048384 (rank : 384)	θ value	0.47712 (rank : 347)
Query Neighborhood Hits	498	Target Neighborhood Hits	753	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SREC2_MOUSE
NC score	0.047222 (rank : 385)	θ value	8.99809 (rank : 497)
Query Neighborhood Hits	498	Target Neighborhood Hits	605	Shared Neighborhood Hits	37
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LTBP2_MOUSE
NC score	0.046857 (rank : 386)	θ value	0.813845 (rank : 359)
Query Neighborhood Hits	498	Target Neighborhood Hits	617	Shared Neighborhood Hits	24
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SREC2_HUMAN
NC score	0.046741 (rank : 387)	θ value	6.88961 (rank : 472)
Query Neighborhood Hits	498	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

RBBP6_HUMAN
NC score	0.046305 (rank : 388)	θ value	1.81305 (rank : 385)
Query Neighborhood Hits	498	Target Neighborhood Hits	1135	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

LEO1_MOUSE
NC score	0.045539 (rank : 389)	θ value	0.125558 (rank : 316)
Query Neighborhood Hits	498	Target Neighborhood Hits	946	Shared Neighborhood Hits	77
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DMP1_MOUSE
NC score	0.044785 (rank : 390)	θ value	3.0926 (rank : 405)
Query Neighborhood Hits	498	Target Neighborhood Hits	498	Shared Neighborhood Hits	63
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TCAL5_HUMAN
NC score	0.044609 (rank : 391)	θ value	0.000786445 (rank : 275)
Query Neighborhood Hits	498	Target Neighborhood Hits	806	Shared Neighborhood Hits	63
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CLSPN_MOUSE
NC score	0.044606 (rank : 392)	θ value	0.0330416 (rank : 296)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

KR10C_HUMAN
NC score	0.043473 (rank : 393)	θ value	4.03905 (rank : 417)
Query Neighborhood Hits	498	Target Neighborhood Hits	219	Shared Neighborhood Hits	16
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LEO1_HUMAN
NC score	0.042914 (rank : 394)	θ value	0.279714 (rank : 324)
Query Neighborhood Hits	498	Target Neighborhood Hits	958	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LARP1_HUMAN
NC score	0.042804 (rank : 395)	θ value	0.0563607 (rank : 305)
Query Neighborhood Hits	498	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

NFH_MOUSE
NC score	0.042756 (rank : 396)	θ value	0.47712 (rank : 346)
Query Neighborhood Hits	498	Target Neighborhood Hits	2247	Shared Neighborhood Hits	150
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RP1L1_HUMAN
NC score	0.042724 (rank : 397)	θ value	5.27518 (rank : 444)
Query Neighborhood Hits	498	Target Neighborhood Hits	1072	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MDN1_HUMAN
NC score	0.041710 (rank : 398)	θ value	5.27518 (rank : 442)
Query Neighborhood Hits	498	Target Neighborhood Hits	662	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NSBP1_MOUSE
NC score	0.041148 (rank : 399)	θ value	2.36792 (rank : 398)
Query Neighborhood Hits	498	Target Neighborhood Hits	681	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SCG3_MOUSE
NC score	0.041007 (rank : 400)	θ value	0.365318 (rank : 335)
Query Neighborhood Hits	498	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

EST1A_HUMAN
NC score	0.040935 (rank : 401)	θ value	0.0736092 (rank : 311)
Query Neighborhood Hits	498	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

MAP1A_HUMAN
NC score	0.040606 (rank : 402)	θ value	5.27518 (rank : 441)
Query Neighborhood Hits	498	Target Neighborhood Hits	1626	Shared Neighborhood Hits	109
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TCOF_HUMAN
NC score	0.040305 (rank : 403)	θ value	0.62314 (rank : 352)
Query Neighborhood Hits	498	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CUBN_HUMAN
NC score	0.038714 (rank : 404)	θ value	5.27518 (rank : 434)
Query Neighborhood Hits	498	Target Neighborhood Hits	482	Shared Neighborhood Hits	17
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

PCLO_MOUSE
NC score	0.038357 (rank : 405)	θ value	1.38821 (rank : 371)
Query Neighborhood Hits	498	Target Neighborhood Hits	2275	Shared Neighborhood Hits	120
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EMIL3_HUMAN
NC score	0.037534 (rank : 406)	θ value	0.0431538 (rank : 301)
Query Neighborhood Hits	498	Target Neighborhood Hits	249	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

HOME2_MOUSE
NC score	0.037465 (rank : 407)	θ value	1.38821 (rank : 369)
Query Neighborhood Hits	498	Target Neighborhood Hits	882	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

EMIL3_MOUSE
NC score	0.037163 (rank : 408)	θ value	0.47712 (rank : 343)
Query Neighborhood Hits	498	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

GOGB1_HUMAN
NC score	0.036862 (rank : 409)	θ value	3.0926 (rank : 407)
Query Neighborhood Hits	498	Target Neighborhood Hits	2297	Shared Neighborhood Hits	120
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NPBL_MOUSE
NC score	0.036854 (rank : 410)	θ value	0.365318 (rank : 333)
Query Neighborhood Hits	498	Target Neighborhood Hits	1041	Shared Neighborhood Hits	83
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

BRD8_MOUSE
NC score	0.036609 (rank : 411)	θ value	0.47712 (rank : 342)
Query Neighborhood Hits	498	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

SMYD3_HUMAN
NC score	0.036266 (rank : 412)	θ value	4.03905 (rank : 425)
Query Neighborhood Hits	498	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TSP3_MOUSE
NC score	0.036253 (rank : 413)	θ value	2.36792 (rank : 402)
Query Neighborhood Hits	498	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

EST1A_MOUSE
NC score	0.035954 (rank : 414)	θ value	0.163984 (rank : 319)
Query Neighborhood Hits	498	Target Neighborhood Hits	138	Shared Neighborhood Hits	16
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

TCRG1_HUMAN
NC score	0.035766 (rank : 415)	θ value	2.36792 (rank : 400)
Query Neighborhood Hits	498	Target Neighborhood Hits	929	Shared Neighborhood Hits	67
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

BAZ1B_HUMAN
NC score	0.035233 (rank : 416)	θ value	1.06291 (rank : 363)
Query Neighborhood Hits	498	Target Neighborhood Hits	701	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

TSP3_HUMAN
NC score	0.035198 (rank : 417)	θ value	3.0926 (rank : 412)
Query Neighborhood Hits	498	Target Neighborhood Hits	250	Shared Neighborhood Hits	22
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

EP15R_MOUSE
NC score	0.035011 (rank : 418)	θ value	0.365318 (rank : 331)
Query Neighborhood Hits	498	Target Neighborhood Hits	1135	Shared Neighborhood Hits	68
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

PEPL_HUMAN
NC score	0.034943 (rank : 419)	θ value	0.365318 (rank : 334)
Query Neighborhood Hits	498	Target Neighborhood Hits	1141	Shared Neighborhood Hits	72
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

TACC1_MOUSE
NC score	0.034911 (rank : 420)	θ value	5.27518 (rank : 448)
Query Neighborhood Hits	498	Target Neighborhood Hits	667	Shared Neighborhood Hits	48
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TCRG1_MOUSE
NC score	0.034442 (rank : 421)	θ value	2.36792 (rank : 401)
Query Neighborhood Hits	498	Target Neighborhood Hits	947	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

PEPL_MOUSE
NC score	0.034146 (rank : 422)	θ value	0.0736092 (rank : 312)
Query Neighborhood Hits	498	Target Neighborhood Hits	1105	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

BRD8_HUMAN
NC score	0.034073 (rank : 423)	θ value	0.47712 (rank : 341)
Query Neighborhood Hits	498	Target Neighborhood Hits	292	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

ADDB_MOUSE
NC score	0.033972 (rank : 424)	θ value	0.0563607 (rank : 303)
Query Neighborhood Hits	498	Target Neighborhood Hits	574	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ZAR1_MOUSE
NC score	0.033960 (rank : 425)	θ value	0.62314 (rank : 354)
Query Neighborhood Hits	498	Target Neighborhood Hits	254	Shared Neighborhood Hits	14
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

EVL_HUMAN
NC score	0.033738 (rank : 426)	θ value	0.813845 (rank : 357)
Query Neighborhood Hits	498	Target Neighborhood Hits	260	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

MAGE1_HUMAN
NC score	0.032845 (rank : 427)	θ value	0.279714 (rank : 325)
Query Neighborhood Hits	498	Target Neighborhood Hits	1389	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ATX2_MOUSE
NC score	0.031358 (rank : 428)	θ value	1.81305 (rank : 377)
Query Neighborhood Hits	498	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

LRRF1_HUMAN
NC score	0.031290 (rank : 429)	θ value	1.38821 (rank : 370)
Query Neighborhood Hits	498	Target Neighborhood Hits	625	Shared Neighborhood Hits	50
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MATN2_MOUSE
NC score	0.030907 (rank : 430)	θ value	8.99809 (rank : 492)
Query Neighborhood Hits	498	Target Neighborhood Hits	356	Shared Neighborhood Hits	21
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

TR150_MOUSE
NC score	0.030778 (rank : 431)	θ value	1.06291 (rank : 366)
Query Neighborhood Hits	498	Target Neighborhood Hits	468	Shared Neighborhood Hits	52
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

CN145_HUMAN
NC score	0.029441 (rank : 432)	θ value	2.36792 (rank : 391)
Query Neighborhood Hits	498	Target Neighborhood Hits	1196	Shared Neighborhood Hits	64
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CCD55_HUMAN
NC score	0.029047 (rank : 433)	θ value	5.27518 (rank : 431)
Query Neighborhood Hits	498	Target Neighborhood Hits	513	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

LRRF1_MOUSE
NC score	0.028535 (rank : 434)	θ value	2.36792 (rank : 396)
Query Neighborhood Hits	498	Target Neighborhood Hits	440	Shared Neighborhood Hits	39
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

SCG3_HUMAN
NC score	0.028249 (rank : 435)	θ value	5.27518 (rank : 445)
Query Neighborhood Hits	498	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXD2, Q96C83, Q96GE8, Q9Y6G7	Gene names	SCG3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

ZN385_HUMAN
NC score	0.027885 (rank : 436)	θ value	0.125558 (rank : 318)
Query Neighborhood Hits	498	Target Neighborhood Hits	614	Shared Neighborhood Hits	31
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

RGS3_MOUSE
NC score	0.027781 (rank : 437)	θ value	4.03905 (rank : 422)
Query Neighborhood Hits	498	Target Neighborhood Hits	1621	Shared Neighborhood Hits	90
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MATR3_MOUSE
NC score	0.026292 (rank : 438)	θ value	0.47712 (rank : 345)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

ATX2_HUMAN
NC score	0.026030 (rank : 439)	θ value	2.36792 (rank : 389)
Query Neighborhood Hits	498	Target Neighborhood Hits	375	Shared Neighborhood Hits	24
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

AKAP2_MOUSE
NC score	0.025829 (rank : 440)	θ value	0.365318 (rank : 327)
Query Neighborhood Hits	498	Target Neighborhood Hits	385	Shared Neighborhood Hits	32
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

PHF20_MOUSE
NC score	0.025291 (rank : 441)	θ value	8.99809 (rank : 495)
Query Neighborhood Hits	498	Target Neighborhood Hits	513	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

SEC63_HUMAN
NC score	0.024963 (rank : 442)	θ value	1.38821 (rank : 372)
Query Neighborhood Hits	498	Target Neighborhood Hits	586	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SDCG8_MOUSE
NC score	0.024822 (rank : 443)	θ value	5.27518 (rank : 446)
Query Neighborhood Hits	498	Target Neighborhood Hits	886	Shared Neighborhood Hits	51
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TNIP3_HUMAN
NC score	0.024625 (rank : 444)	θ value	4.03905 (rank : 428)
Query Neighborhood Hits	498	Target Neighborhood Hits	511	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

CJ012_HUMAN
NC score	0.024045 (rank : 445)	θ value	6.88961 (rank : 458)
Query Neighborhood Hits	498	Target Neighborhood Hits	467	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

SYNC_MOUSE
NC score	0.023994 (rank : 446)	θ value	0.47712 (rank : 349)
Query Neighborhood Hits	498	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNC_HUMAN
NC score	0.023832 (rank : 447)	θ value	0.813845 (rank : 361)
Query Neighborhood Hits	498	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

CCD45_HUMAN
NC score	0.023382 (rank : 448)	θ value	0.813845 (rank : 356)
Query Neighborhood Hits	498	Target Neighborhood Hits	525	Shared Neighborhood Hits	34
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

SAPS1_HUMAN
NC score	0.023171 (rank : 449)	θ value	1.06291 (rank : 365)
Query Neighborhood Hits	498	Target Neighborhood Hits	704	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TCAL3_HUMAN
NC score	0.023103 (rank : 450)	θ value	4.03905 (rank : 427)
Query Neighborhood Hits	498	Target Neighborhood Hits	274	Shared Neighborhood Hits	27
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

EVL_MOUSE
NC score	0.023027 (rank : 451)	θ value	1.81305 (rank : 381)
Query Neighborhood Hits	498	Target Neighborhood Hits	203	Shared Neighborhood Hits	22
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

TRM6_MOUSE
NC score	0.023017 (rank : 452)	θ value	1.38821 (rank : 376)
Query Neighborhood Hits	498	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CE96, Q3TJZ8, Q3TME7, Q6ZPW8, Q80Y59, Q8CEU0	Gene names	Trm6, Kiaa1153
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6).

MATR3_HUMAN
NC score	0.022920 (rank : 453)	θ value	1.81305 (rank : 383)
Query Neighborhood Hits	498	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MBB1A_MOUSE
NC score	0.022801 (rank : 454)	θ value	2.36792 (rank : 397)
Query Neighborhood Hits	498	Target Neighborhood Hits	233	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

SEC63_MOUSE
NC score	0.022680 (rank : 455)	θ value	1.38821 (rank : 373)
Query Neighborhood Hits	498	Target Neighborhood Hits	601	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

CJ049_HUMAN
NC score	0.022664 (rank : 456)	θ value	3.0926 (rank : 403)
Query Neighborhood Hits	498	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

RFC1_MOUSE
NC score	0.022006 (rank : 457)	θ value	3.0926 (rank : 409)
Query Neighborhood Hits	498	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

CI093_HUMAN
NC score	0.021397 (rank : 458)	θ value	8.99809 (rank : 483)
Query Neighborhood Hits	498	Target Neighborhood Hits	1088	Shared Neighborhood Hits	56
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CC47_MOUSE
NC score	0.021355 (rank : 459)	θ value	2.36792 (rank : 390)
Query Neighborhood Hits	498	Target Neighborhood Hits	245	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

SCG2_HUMAN
NC score	0.021116 (rank : 460)	θ value	6.88961 (rank : 469)
Query Neighborhood Hits	498	Target Neighborhood Hits	190	Shared Neighborhood Hits	25
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

GON4L_HUMAN
NC score	0.021100 (rank : 461)	θ value	2.36792 (rank : 394)
Query Neighborhood Hits	498	Target Neighborhood Hits	555	Shared Neighborhood Hits	52
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LSD1_HUMAN
NC score	0.019982 (rank : 462)	θ value	3.0926 (rank : 408)
Query Neighborhood Hits	498	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

CEP57_MOUSE
NC score	0.019916 (rank : 463)	θ value	8.99809 (rank : 481)
Query Neighborhood Hits	498	Target Neighborhood Hits	580	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

K0460_MOUSE
NC score	0.019897 (rank : 464)	θ value	4.03905 (rank : 416)
Query Neighborhood Hits	498	Target Neighborhood Hits	374	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

SVIL_MOUSE
NC score	0.018304 (rank : 465)	θ value	4.03905 (rank : 426)
Query Neighborhood Hits	498	Target Neighborhood Hits	439	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MAP2_MOUSE
NC score	0.018064 (rank : 466)	θ value	6.88961 (rank : 467)
Query Neighborhood Hits	498	Target Neighborhood Hits	342	Shared Neighborhood Hits	44
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

ADA30_HUMAN
NC score	0.017700 (rank : 467)	θ value	0.21417 (rank : 323)
Query Neighborhood Hits	498	Target Neighborhood Hits	391	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

MUCDL_MOUSE
NC score	0.017131 (rank : 468)	θ value	5.27518 (rank : 443)
Query Neighborhood Hits	498	Target Neighborhood Hits	461	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NUP53_HUMAN
NC score	0.016672 (rank : 469)	θ value	1.81305 (rank : 384)
Query Neighborhood Hits	498	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

DMN_HUMAN
NC score	0.016453 (rank : 470)	θ value	2.36792 (rank : 392)
Query Neighborhood Hits	498	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

E41L2_MOUSE
NC score	0.016248 (rank : 471)	θ value	0.62314 (rank : 351)
Query Neighborhood Hits	498	Target Neighborhood Hits	459	Shared Neighborhood Hits	48
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

F10A1_HUMAN
NC score	0.015815 (rank : 472)	θ value	5.27518 (rank : 436)
Query Neighborhood Hits	498	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

SYP2L_MOUSE
NC score	0.015319 (rank : 473)	θ value	2.36792 (rank : 399)
Query Neighborhood Hits	498	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

F10A4_HUMAN
NC score	0.015168 (rank : 474)	θ value	5.27518 (rank : 437)
Query Neighborhood Hits	498	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

TF3C1_MOUSE
NC score	0.014924 (rank : 475)	θ value	1.81305 (rank : 386)
Query Neighborhood Hits	498	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TCGAP_MOUSE
NC score	0.014714 (rank : 476)	θ value	5.27518 (rank : 449)
Query Neighborhood Hits	498	Target Neighborhood Hits	409	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

DNJC8_HUMAN
NC score	0.014558 (rank : 477)	θ value	1.81305 (rank : 379)
Query Neighborhood Hits	498	Target Neighborhood Hits	380	Shared Neighborhood Hits	21
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

NEIL3_MOUSE
NC score	0.014336 (rank : 478)	θ value	4.03905 (rank : 418)
Query Neighborhood Hits	498	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

IDLC_MOUSE
NC score	0.014152 (rank : 479)	θ value	8.99809 (rank : 489)
Query Neighborhood Hits	498	Target Neighborhood Hits	321	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

CO1A1_HUMAN
NC score	0.013989 (rank : 480)	θ value	5.27518 (rank : 432)
Query Neighborhood Hits	498	Target Neighborhood Hits	475	Shared Neighborhood Hits	32
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

PCGF4_HUMAN
NC score	0.013865 (rank : 481)	θ value	4.03905 (rank : 420)
Query Neighborhood Hits	498	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.013769 (rank : 482)	θ value	4.03905 (rank : 421)
Query Neighborhood Hits	498	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

IDLC_HUMAN
NC score	0.013710 (rank : 483)	θ value	8.99809 (rank : 488)
Query Neighborhood Hits	498	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

DNJC8_MOUSE
NC score	0.013688 (rank : 484)	θ value	1.81305 (rank : 380)
Query Neighborhood Hits	498	Target Neighborhood Hits	392	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

SMS2_HUMAN
NC score	0.013390 (rank : 485)	θ value	1.38821 (rank : 375)
Query Neighborhood Hits	498	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

F10A5_HUMAN
NC score	0.013189 (rank : 486)	θ value	6.88961 (rank : 463)
Query Neighborhood Hits	498	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

ZNFX1_HUMAN
NC score	0.012010 (rank : 487)	θ value	8.99809 (rank : 498)
Query Neighborhood Hits	498	Target Neighborhood Hits	308	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

SH24A_MOUSE
NC score	0.011568 (rank : 488)	θ value	4.03905 (rank : 424)
Query Neighborhood Hits	498	Target Neighborhood Hits	326	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

CGRE1_HUMAN
NC score	0.011536 (rank : 489)	θ value	8.99809 (rank : 482)
Query Neighborhood Hits	498	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

JHD2C_MOUSE
NC score	0.011409 (rank : 490)	θ value	8.99809 (rank : 490)
Query Neighborhood Hits	498	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

IF4E3_MOUSE
NC score	0.011055 (rank : 491)	θ value	5.27518 (rank : 440)
Query Neighborhood Hits	498	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMB3, O88503, Q3UCK2	Gene names	Eif4el3
Domain Architecture
Description	Eukaryotic translation initiation factor 4E type 3 (eIF4E type 3) (eIF-4E type 3) (mRNA cap-binding protein type 3) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP).

DJC12_HUMAN
NC score	0.011041 (rank : 492)	θ value	3.0926 (rank : 404)
Query Neighborhood Hits	498	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

SESN1_HUMAN
NC score	0.010904 (rank : 493)	θ value	1.38821 (rank : 374)
Query Neighborhood Hits	498	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

PKHA2_HUMAN
NC score	0.010810 (rank : 494)	θ value	8.99809 (rank : 496)
Query Neighborhood Hits	498	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

SDPR_HUMAN
NC score	0.010081 (rank : 495)	θ value	3.0926 (rank : 410)
Query Neighborhood Hits	498	Target Neighborhood Hits	337	Shared Neighborhood Hits	23
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

MERL_HUMAN
NC score	0.010067 (rank : 496)	θ value	8.99809 (rank : 493)
Query Neighborhood Hits	498	Target Neighborhood Hits	532	Shared Neighborhood Hits	32
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

XRN1_MOUSE
NC score	0.009999 (rank : 497)	θ value	1.81305 (rank : 387)
Query Neighborhood Hits	498	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

GGA1_HUMAN
NC score	0.009268 (rank : 498)	θ value	8.99809 (rank : 485)
Query Neighborhood Hits	498	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

ZNFX1_MOUSE
NC score	0.008535 (rank : 499)	θ value	5.27518 (rank : 452)
Query Neighborhood Hits	498	Target Neighborhood Hits	407	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

COHA1_MOUSE
NC score	0.008483 (rank : 500)	θ value	6.88961 (rank : 460)
Query Neighborhood Hits	498	Target Neighborhood Hits	414	Shared Neighborhood Hits	33
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

TTC1_HUMAN
NC score	0.008000 (rank : 501)	θ value	6.88961 (rank : 475)
Query Neighborhood Hits	498	Target Neighborhood Hits	417	Shared Neighborhood Hits	27
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

SEMG1_HUMAN
NC score	0.007870 (rank : 502)	θ value	5.27518 (rank : 447)
Query Neighborhood Hits	498	Target Neighborhood Hits	200	Shared Neighborhood Hits	15
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

AGGF1_HUMAN
NC score	0.007655 (rank : 503)	θ value	8.99809 (rank : 477)
Query Neighborhood Hits	498	Target Neighborhood Hits	271	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

UBP51_HUMAN
NC score	0.007620 (rank : 504)	θ value	0.365318 (rank : 339)
Query Neighborhood Hits	498	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

SEPT7_HUMAN
NC score	0.007368 (rank : 505)	θ value	4.03905 (rank : 423)
Query Neighborhood Hits	498	Target Neighborhood Hits	385	Shared Neighborhood Hits	25
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

CLGN_MOUSE
NC score	0.007227 (rank : 506)	θ value	6.88961 (rank : 459)
Query Neighborhood Hits	498	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

IF2M_MOUSE
NC score	0.007138 (rank : 507)	θ value	6.88961 (rank : 465)
Query Neighborhood Hits	498	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

NEK1_MOUSE
NC score	0.006549 (rank : 508)	θ value	0.813845 (rank : 360)
Query Neighborhood Hits	498	Target Neighborhood Hits	1311	Shared Neighborhood Hits	58
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

CSPG5_MOUSE
NC score	0.006372 (rank : 509)	θ value	6.88961 (rank : 461)
Query Neighborhood Hits	498	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

MYLK_MOUSE
NC score	0.006294 (rank : 510)	θ value	6.88961 (rank : 468)
Query Neighborhood Hits	498	Target Neighborhood Hits	1489	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ADA28_MOUSE
NC score	0.005924 (rank : 511)	θ value	6.88961 (rank : 453)
Query Neighborhood Hits	498	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

HDAC9_MOUSE
NC score	0.005903 (rank : 512)	θ value	8.99809 (rank : 486)
Query Neighborhood Hits	498	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

MAST2_MOUSE
NC score	0.005353 (rank : 513)	θ value	0.47712 (rank : 344)
Query Neighborhood Hits	498	Target Neighborhood Hits	1110	Shared Neighborhood Hits	37
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST1_HUMAN
NC score	0.004925 (rank : 514)	θ value	8.99809 (rank : 491)
Query Neighborhood Hits	498	Target Neighborhood Hits	1146	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

AR13B_HUMAN
NC score	0.004912 (rank : 515)	θ value	2.36792 (rank : 388)
Query Neighborhood Hits	498	Target Neighborhood Hits	528	Shared Neighborhood Hits	30
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

AQR_HUMAN
NC score	0.004792 (rank : 516)	θ value	6.88961 (rank : 456)
Query Neighborhood Hits	498	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

BSCL2_MOUSE
NC score	0.004024 (rank : 517)	θ value	8.99809 (rank : 480)
Query Neighborhood Hits	498	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

AAAD_MOUSE
NC score	0.003639 (rank : 518)	θ value	8.99809 (rank : 476)
Query Neighborhood Hits	498	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

GHR_MOUSE
NC score	0.003639 (rank : 519)	θ value	6.88961 (rank : 464)
Query Neighborhood Hits	498	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

ETV1_HUMAN
NC score	0.002352 (rank : 520)	θ value	6.88961 (rank : 462)
Query Neighborhood Hits	498	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

FOXN3_HUMAN
NC score	0.002283 (rank : 521)	θ value	2.36792 (rank : 393)
Query Neighborhood Hits	498	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

ETV1_MOUSE
NC score	0.002196 (rank : 522)	θ value	8.99809 (rank : 484)
Query Neighborhood Hits	498	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ZHX2_MOUSE
NC score	0.002146 (rank : 523)	θ value	3.0926 (rank : 413)
Query Neighborhood Hits	498	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

OAS3_HUMAN
NC score	0.002072 (rank : 524)	θ value	8.99809 (rank : 494)
Query Neighborhood Hits	498	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

CO7A1_HUMAN
NC score	0.002020 (rank : 525)	θ value	5.27518 (rank : 433)
Query Neighborhood Hits	498	Target Neighborhood Hits	807	Shared Neighborhood Hits	41
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CAC1C_HUMAN
NC score	0.001930 (rank : 526)	θ value	1.81305 (rank : 378)
Query Neighborhood Hits	498	Target Neighborhood Hits	158	Shared Neighborhood Hits	14
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

FLNA_MOUSE
NC score	0.001062 (rank : 527)	θ value	5.27518 (rank : 439)
Query Neighborhood Hits	498	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_HUMAN
NC score	0.001022 (rank : 528)	θ value	5.27518 (rank : 438)
Query Neighborhood Hits	498	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

TSH1_MOUSE
NC score	0.000917 (rank : 529)	θ value	6.88961 (rank : 474)
Query Neighborhood Hits	498	Target Neighborhood Hits	675	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

SRPK1_MOUSE
NC score	0.000058 (rank : 530)	θ value	6.88961 (rank : 473)
Query Neighborhood Hits	498	Target Neighborhood Hits	639	Shared Neighborhood Hits	22
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

DMXL2_HUMAN
NC score	-0.000396 (rank : 531)	θ value	3.0926 (rank : 406)
Query Neighborhood Hits	498	Target Neighborhood Hits	374	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

DHX34_MOUSE
NC score	-0.000955 (rank : 532)	θ value	5.27518 (rank : 435)
Query Neighborhood Hits	498	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

SPAST_MOUSE
NC score	-0.001446 (rank : 533)	θ value	6.88961 (rank : 471)
Query Neighborhood Hits	498	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

ITA1_HUMAN
NC score	-0.001588 (rank : 534)	θ value	6.88961 (rank : 466)
Query Neighborhood Hits	498	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	P56199	Gene names	ITGA1
Domain Architecture	No domain graphic available
Description	Integrin alpha-1 (Laminin and collagen receptor) (VLA-1) (CD49a antigen).

SOX7_MOUSE
NC score	-0.002233 (rank : 535)	θ value	6.88961 (rank : 470)
Query Neighborhood Hits	498	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

ATS8_MOUSE
NC score	-0.002464 (rank : 536)	θ value	6.88961 (rank : 457)
Query Neighborhood Hits	498	Target Neighborhood Hits	139	Shared Neighborhood Hits	6
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ZN687_HUMAN
NC score	-0.002478 (rank : 537)	θ value	4.03905 (rank : 430)
Query Neighborhood Hits	498	Target Neighborhood Hits	1244	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

PCD12_MOUSE
NC score	-0.005041 (rank : 538)	θ value	4.03905 (rank : 419)
Query Neighborhood Hits	498	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

ZN447_HUMAN
NC score	-0.005972 (rank : 539)	θ value	0.365318 (rank : 340)
Query Neighborhood Hits	498	Target Neighborhood Hits	899	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

HV3B_HUMAN
NC score	-0.006752 (rank : 540)	θ value	8.99809 (rank : 487)
Query Neighborhood Hits	498	Target Neighborhood Hits	253	Shared Neighborhood Hits	2
SwissProt Accessions	P01763	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region WEA.

GPR32_HUMAN
NC score	-0.009973 (rank : 541)	θ value	4.03905 (rank : 415)
Query Neighborhood Hits	498	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	O75388, Q6NWS5	Gene names	GPR32
Domain Architecture
Description	Probable G-protein coupled receptor 32.

ZBT24_HUMAN
NC score	-0.010749 (rank : 542)	θ value	0.0330416 (rank : 298)
Query Neighborhood Hits	498	Target Neighborhood Hits	870	Shared Neighborhood Hits	21
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).

ZN683_HUMAN
NC score	-0.013883 (rank : 543)	θ value	5.27518 (rank : 451)
Query Neighborhood Hits	498	Target Neighborhood Hits	750	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

ZN394_MOUSE
NC score	-0.013979 (rank : 544)	θ value	3.0926 (rank : 414)
Query Neighborhood Hits	498	Target Neighborhood Hits	738	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1D9, Q3U4Z1, Q9CYV9, Q9CZG8	Gene names	Znf394, Zfp94, Zfp99
Domain Architecture
Description	Zinc finger protein 394 (Zinc finger protein 94) (Zfp-94).

ADRB1_HUMAN
NC score	-0.014067 (rank : 545)	θ value	6.88961 (rank : 454)
Query Neighborhood Hits	498	Target Neighborhood Hits	866	Shared Neighborhood Hits	4
SwissProt Accessions	P08588, Q9UKG7, Q9UKG8	Gene names	ADRB1, ADRB1R, B1AR
Domain Architecture
Description	Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1 adrenoreceptor).