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Network neighborhood for query Sequence : ZNFX1_HUMAN

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ZNFX1_HUMAN
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZNFX1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	308	Target Neighborhood Hits	308	Shared Neighborhood Hits	308
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	0 (rank : 2)	NC score	0.959028 (rank : 2)
Query Neighborhood Hits	308	Target Neighborhood Hits	407	Shared Neighborhood Hits	220
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

RENT1_HUMAN
θ value	4.42448e-31 (rank : 3)	NC score	0.567569 (rank : 3)
Query Neighborhood Hits	308	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	5.77852e-31 (rank : 4)	NC score	0.567191 (rank : 4)
Query Neighborhood Hits	308	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

AQR_HUMAN
θ value	2.27234e-27 (rank : 5)	NC score	0.520763 (rank : 6)
Query Neighborhood Hits	308	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	2.27234e-27 (rank : 6)	NC score	0.521767 (rank : 5)
Query Neighborhood Hits	308	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

SETX_HUMAN
θ value	7.32683e-18 (rank : 7)	NC score	0.473584 (rank : 8)
Query Neighborhood Hits	308	Target Neighborhood Hits	368	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

NFX1_HUMAN
θ value	2.13179e-17 (rank : 8)	NC score	0.476793 (rank : 7)
Query Neighborhood Hits	308	Target Neighborhood Hits	405	Shared Neighborhood Hits	104
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PR285_HUMAN
θ value	1.29331e-14 (rank : 9)	NC score	0.460263 (rank : 11)
Query Neighborhood Hits	308	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

SMBP2_HUMAN
θ value	5.43371e-13 (rank : 10)	NC score	0.471664 (rank : 10)
Query Neighborhood Hits	308	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
θ value	5.43371e-13 (rank : 11)	NC score	0.472511 (rank : 9)
Query Neighborhood Hits	308	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

KR106_HUMAN
θ value	2.69671e-12 (rank : 12)	NC score	0.416723 (rank : 21)
Query Neighborhood Hits	308	Target Neighborhood Hits	347	Shared Neighborhood Hits	117
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

M10L1_HUMAN
θ value	2.28291e-11 (rank : 13)	NC score	0.421412 (rank : 17)
Query Neighborhood Hits	308	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

KR107_HUMAN
θ value	2.98157e-11 (rank : 14)	NC score	0.396845 (rank : 30)
Query Neighborhood Hits	308	Target Neighborhood Hits	330	Shared Neighborhood Hits	116
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR104_HUMAN
θ value	8.67504e-11 (rank : 15)	NC score	0.341837 (rank : 43)
Query Neighborhood Hits	308	Target Neighborhood Hits	313	Shared Neighborhood Hits	88
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

MOV10_MOUSE
θ value	5.62301e-10 (rank : 16)	NC score	0.417421 (rank : 19)
Query Neighborhood Hits	308	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

M10L1_MOUSE
θ value	7.34386e-10 (rank : 17)	NC score	0.408459 (rank : 22)
Query Neighborhood Hits	308	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

MOV10_HUMAN
θ value	7.34386e-10 (rank : 18)	NC score	0.417419 (rank : 20)
Query Neighborhood Hits	308	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

KR101_HUMAN
θ value	1.63604e-09 (rank : 19)	NC score	0.369154 (rank : 38)
Query Neighborhood Hits	308	Target Neighborhood Hits	261	Shared Neighborhood Hits	86
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR109_HUMAN
θ value	1.63604e-09 (rank : 20)	NC score	0.386338 (rank : 33)
Query Neighborhood Hits	308	Target Neighborhood Hits	226	Shared Neighborhood Hits	85
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

SREC_HUMAN
θ value	2.13673e-09 (rank : 21)	NC score	0.278329 (rank : 53)
Query Neighborhood Hits	308	Target Neighborhood Hits	645	Shared Neighborhood Hits	149
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KRA98_HUMAN
θ value	6.21693e-09 (rank : 22)	NC score	0.406968 (rank : 23)
Query Neighborhood Hits	308	Target Neighborhood Hits	185	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

HELZ_HUMAN
θ value	1.06045e-08 (rank : 23)	NC score	0.390234 (rank : 31)
Query Neighborhood Hits	308	Target Neighborhood Hits	198	Shared Neighborhood Hits	17
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

KRA53_HUMAN
θ value	1.06045e-08 (rank : 24)	NC score	0.272098 (rank : 55)
Query Neighborhood Hits	308	Target Neighborhood Hits	331	Shared Neighborhood Hits	98
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KR10A_HUMAN
θ value	2.36244e-08 (rank : 25)	NC score	0.448714 (rank : 13)
Query Neighborhood Hits	308	Target Neighborhood Hits	232	Shared Neighborhood Hits	90
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR105_HUMAN
θ value	3.08544e-08 (rank : 26)	NC score	0.438679 (rank : 14)
Query Neighborhood Hits	308	Target Neighborhood Hits	271	Shared Neighborhood Hits	103
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR108_HUMAN
θ value	6.87365e-08 (rank : 27)	NC score	0.370067 (rank : 37)
Query Neighborhood Hits	308	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR10B_HUMAN
θ value	8.97725e-08 (rank : 28)	NC score	0.438460 (rank : 15)
Query Neighborhood Hits	308	Target Neighborhood Hits	269	Shared Neighborhood Hits	103
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR412_HUMAN
θ value	8.97725e-08 (rank : 29)	NC score	0.399768 (rank : 27)
Query Neighborhood Hits	308	Target Neighborhood Hits	178	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA99_HUMAN
θ value	8.97725e-08 (rank : 30)	NC score	0.404792 (rank : 24)
Query Neighborhood Hits	308	Target Neighborhood Hits	173	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KRA47_HUMAN
θ value	1.17247e-07 (rank : 31)	NC score	0.403271 (rank : 26)
Query Neighborhood Hits	308	Target Neighborhood Hits	204	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA92_HUMAN
θ value	1.53129e-07 (rank : 32)	NC score	0.404779 (rank : 25)
Query Neighborhood Hits	308	Target Neighborhood Hits	198	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

SREC2_MOUSE
θ value	1.53129e-07 (rank : 33)	NC score	0.222297 (rank : 76)
Query Neighborhood Hits	308	Target Neighborhood Hits	605	Shared Neighborhood Hits	133
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KR102_HUMAN
θ value	3.41135e-07 (rank : 34)	NC score	0.380675 (rank : 35)
Query Neighborhood Hits	308	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA45_HUMAN
θ value	3.41135e-07 (rank : 35)	NC score	0.398885 (rank : 29)
Query Neighborhood Hits	308	Target Neighborhood Hits	194	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA93_HUMAN
θ value	4.45536e-07 (rank : 36)	NC score	0.388839 (rank : 32)
Query Neighborhood Hits	308	Target Neighborhood Hits	203	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	4.45536e-07 (rank : 37)	NC score	0.418661 (rank : 18)
Query Neighborhood Hits	308	Target Neighborhood Hits	204	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KR10C_HUMAN
θ value	5.81887e-07 (rank : 38)	NC score	0.372210 (rank : 36)
Query Neighborhood Hits	308	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

PCSK5_MOUSE
θ value	5.81887e-07 (rank : 39)	NC score	0.200218 (rank : 88)
Query Neighborhood Hits	308	Target Neighborhood Hits	613	Shared Neighborhood Hits	132
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

KRA58_HUMAN
θ value	9.92553e-07 (rank : 40)	NC score	0.270825 (rank : 58)
Query Neighborhood Hits	308	Target Neighborhood Hits	324	Shared Neighborhood Hits	97
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

FRAS1_MOUSE
θ value	2.88788e-06 (rank : 41)	NC score	0.247629 (rank : 71)
Query Neighborhood Hits	308	Target Neighborhood Hits	747	Shared Neighborhood Hits	140
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR414_HUMAN
θ value	6.43352e-06 (rank : 42)	NC score	0.366109 (rank : 41)
Query Neighborhood Hits	308	Target Neighborhood Hits	199	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

INSR_MOUSE
θ value	8.40245e-06 (rank : 43)	NC score	0.071204 (rank : 235)
Query Neighborhood Hits	308	Target Neighborhood Hits	968	Shared Neighborhood Hits	72
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

SPR2H_MOUSE
θ value	8.40245e-06 (rank : 44)	NC score	0.282567 (rank : 52)
Query Neighborhood Hits	308	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

KRA59_HUMAN
θ value	1.09739e-05 (rank : 45)	NC score	0.249702 (rank : 70)
Query Neighborhood Hits	308	Target Neighborhood Hits	310	Shared Neighborhood Hits	79
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

SPR2B_MOUSE
θ value	1.09739e-05 (rank : 46)	NC score	0.301105 (rank : 47)
Query Neighborhood Hits	308	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

INSR_HUMAN
θ value	1.43324e-05 (rank : 47)	NC score	0.071317 (rank : 234)
Query Neighborhood Hits	308	Target Neighborhood Hits	963	Shared Neighborhood Hits	70
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

SPR2D_MOUSE
θ value	1.43324e-05 (rank : 48)	NC score	0.314879 (rank : 46)
Query Neighborhood Hits	308	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

KR511_HUMAN
θ value	1.87187e-05 (rank : 49)	NC score	0.289830 (rank : 50)
Query Neighborhood Hits	308	Target Neighborhood Hits	231	Shared Neighborhood Hits	66
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA55_HUMAN
θ value	1.87187e-05 (rank : 50)	NC score	0.271283 (rank : 57)
Query Neighborhood Hits	308	Target Neighborhood Hits	257	Shared Neighborhood Hits	76
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

FRAS1_HUMAN
θ value	3.19293e-05 (rank : 51)	NC score	0.237447 (rank : 72)
Query Neighborhood Hits	308	Target Neighborhood Hits	759	Shared Neighborhood Hits	135
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA44_HUMAN
θ value	3.19293e-05 (rank : 52)	NC score	0.350473 (rank : 42)
Query Neighborhood Hits	308	Target Neighborhood Hits	162	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KR103_HUMAN
θ value	4.1701e-05 (rank : 53)	NC score	0.436171 (rank : 16)
Query Neighborhood Hits	308	Target Neighborhood Hits	212	Shared Neighborhood Hits	100
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

MEGF6_HUMAN
θ value	7.1131e-05 (rank : 54)	NC score	0.172481 (rank : 98)
Query Neighborhood Hits	308	Target Neighborhood Hits	671	Shared Neighborhood Hits	155
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

EGFR_MOUSE
θ value	9.29e-05 (rank : 55)	NC score	0.063571 (rank : 265)
Query Neighborhood Hits	308	Target Neighborhood Hits	927	Shared Neighborhood Hits	42
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

KRA51_HUMAN
θ value	9.29e-05 (rank : 56)	NC score	0.200829 (rank : 87)
Query Neighborhood Hits	308	Target Neighborhood Hits	288	Shared Neighborhood Hits	71
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SPR2G_MOUSE
θ value	0.000121331 (rank : 57)	NC score	0.295067 (rank : 49)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

KRA57_HUMAN
θ value	0.000158464 (rank : 58)	NC score	0.258366 (rank : 65)
Query Neighborhood Hits	308	Target Neighborhood Hits	269	Shared Neighborhood Hits	81
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ERBB3_HUMAN
θ value	0.000270298 (rank : 59)	NC score	0.076456 (rank : 228)
Query Neighborhood Hits	308	Target Neighborhood Hits	918	Shared Neighborhood Hits	63
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

KR510_HUMAN
θ value	0.000270298 (rank : 60)	NC score	0.272747 (rank : 54)
Query Neighborhood Hits	308	Target Neighborhood Hits	217	Shared Neighborhood Hits	65
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

MYCB2_HUMAN
θ value	0.000270298 (rank : 61)	NC score	0.116699 (rank : 123)
Query Neighborhood Hits	308	Target Neighborhood Hits	390	Shared Neighborhood Hits	22
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	0.000270298 (rank : 62)	NC score	0.117762 (rank : 122)
Query Neighborhood Hits	308	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SREC2_HUMAN
θ value	0.00035302 (rank : 63)	NC score	0.214715 (rank : 80)
Query Neighborhood Hits	308	Target Neighborhood Hits	645	Shared Neighborhood Hits	132
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

KRA54_HUMAN
θ value	0.000461057 (rank : 64)	NC score	0.258820 (rank : 64)
Query Neighborhood Hits	308	Target Neighborhood Hits	270	Shared Neighborhood Hits	76
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA42_HUMAN
θ value	0.00134147 (rank : 65)	NC score	0.399656 (rank : 28)
Query Neighborhood Hits	308	Target Neighborhood Hits	149	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

VWF_MOUSE
θ value	0.00134147 (rank : 66)	NC score	0.169682 (rank : 101)
Query Neighborhood Hits	308	Target Neighborhood Hits	381	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KR410_HUMAN
θ value	0.00175202 (rank : 67)	NC score	0.385535 (rank : 34)
Query Neighborhood Hits	308	Target Neighborhood Hits	156	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

SPR2F_HUMAN
θ value	0.00175202 (rank : 68)	NC score	0.295722 (rank : 48)
Query Neighborhood Hits	308	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SSPO_MOUSE
θ value	0.00175202 (rank : 69)	NC score	0.152418 (rank : 105)
Query Neighborhood Hits	308	Target Neighborhood Hits	800	Shared Neighborhood Hits	145
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ZAN_HUMAN
θ value	0.00228821 (rank : 70)	NC score	0.161529 (rank : 104)
Query Neighborhood Hits	308	Target Neighborhood Hits	679	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SPR2E_HUMAN
θ value	0.00298849 (rank : 71)	NC score	0.267415 (rank : 59)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

TENA_HUMAN
θ value	0.00390308 (rank : 72)	NC score	0.141852 (rank : 109)
Query Neighborhood Hits	308	Target Neighborhood Hits	631	Shared Neighborhood Hits	115
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

EGFR_HUMAN
θ value	0.00509761 (rank : 73)	NC score	0.063388 (rank : 266)
Query Neighborhood Hits	308	Target Neighborhood Hits	939	Shared Neighborhood Hits	63
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ERBB2_MOUSE
θ value	0.00509761 (rank : 74)	NC score	0.061682 (rank : 275)
Query Neighborhood Hits	308	Target Neighborhood Hits	918	Shared Neighborhood Hits	48
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_MOUSE
θ value	0.00509761 (rank : 75)	NC score	0.070806 (rank : 239)
Query Neighborhood Hits	308	Target Neighborhood Hits	898	Shared Neighborhood Hits	54
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

MCSP_MOUSE
θ value	0.00665767 (rank : 76)	NC score	0.222310 (rank : 75)
Query Neighborhood Hits	308	Target Neighborhood Hits	108	Shared Neighborhood Hits	35
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SPR2I_MOUSE
θ value	0.00665767 (rank : 77)	NC score	0.251439 (rank : 68)
Query Neighborhood Hits	308	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

KRA52_HUMAN
θ value	0.00869519 (rank : 78)	NC score	0.252812 (rank : 67)
Query Neighborhood Hits	308	Target Neighborhood Hits	236	Shared Neighborhood Hits	75
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

IGF1R_HUMAN
θ value	0.0113563 (rank : 79)	NC score	0.070151 (rank : 241)
Query Neighborhood Hits	308	Target Neighborhood Hits	977	Shared Neighborhood Hits	86
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KRA11_HUMAN
θ value	0.0148317 (rank : 80)	NC score	0.209193 (rank : 82)
Query Neighborhood Hits	308	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	0.0148317 (rank : 81)	NC score	0.255065 (rank : 66)
Query Neighborhood Hits	308	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA24_HUMAN
θ value	0.0148317 (rank : 82)	NC score	0.451834 (rank : 12)
Query Neighborhood Hits	308	Target Neighborhood Hits	192	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

SPR2E_MOUSE
θ value	0.0148317 (rank : 83)	NC score	0.249971 (rank : 69)
Query Neighborhood Hits	308	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

ADAM7_HUMAN
θ value	0.0193708 (rank : 84)	NC score	0.054413 (rank : 314)
Query Neighborhood Hits	308	Target Neighborhood Hits	221	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

KR413_HUMAN
θ value	0.0193708 (rank : 85)	NC score	0.334741 (rank : 44)
Query Neighborhood Hits	308	Target Neighborhood Hits	112	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

VWF_HUMAN
θ value	0.0193708 (rank : 86)	NC score	0.177711 (rank : 96)
Query Neighborhood Hits	308	Target Neighborhood Hits	396	Shared Neighborhood Hits	113
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	0.0193708 (rank : 87)	NC score	0.287312 (rank : 51)
Query Neighborhood Hits	308	Target Neighborhood Hits	138	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ZAN_MOUSE
θ value	0.0252991 (rank : 88)	NC score	0.215972 (rank : 79)
Query Neighborhood Hits	308	Target Neighborhood Hits	808	Shared Neighborhood Hits	160
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

BPAEA_HUMAN
θ value	0.0431538 (rank : 89)	NC score	0.055683 (rank : 308)
Query Neighborhood Hits	308	Target Neighborhood Hits	1369	Shared Neighborhood Hits	67
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD42_HUMAN
θ value	0.0431538 (rank : 90)	NC score	0.063170 (rank : 267)
Query Neighborhood Hits	308	Target Neighborhood Hits	406	Shared Neighborhood Hits	40
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

DYHC_HUMAN
θ value	0.0431538 (rank : 91)	NC score	0.079760 (rank : 212)
Query Neighborhood Hits	308	Target Neighborhood Hits	733	Shared Neighborhood Hits	64
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.0431538 (rank : 92)	NC score	0.079769 (rank : 211)
Query Neighborhood Hits	308	Target Neighborhood Hits	729	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

ERBB4_HUMAN
θ value	0.0431538 (rank : 93)	NC score	0.061400 (rank : 277)
Query Neighborhood Hits	308	Target Neighborhood Hits	910	Shared Neighborhood Hits	53
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

BPA1_MOUSE
θ value	0.0563607 (rank : 94)	NC score	0.049567 (rank : 338)
Query Neighborhood Hits	308	Target Neighborhood Hits	1477	Shared Neighborhood Hits	73
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MUC5B_HUMAN
θ value	0.0563607 (rank : 95)	NC score	0.203889 (rank : 84)
Query Neighborhood Hits	308	Target Neighborhood Hits	1020	Shared Neighborhood Hits	138
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PCSK5_HUMAN
θ value	0.0563607 (rank : 96)	NC score	0.112174 (rank : 131)
Query Neighborhood Hits	308	Target Neighborhood Hits	291	Shared Neighborhood Hits	74
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

IGF1R_MOUSE
θ value	0.0736092 (rank : 97)	NC score	0.064690 (rank : 257)
Query Neighborhood Hits	308	Target Neighborhood Hits	973	Shared Neighborhood Hits	79
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KRA56_HUMAN
θ value	0.0736092 (rank : 98)	NC score	0.194114 (rank : 91)
Query Neighborhood Hits	308	Target Neighborhood Hits	207	Shared Neighborhood Hits	62
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

SPR2F_MOUSE
θ value	0.0736092 (rank : 99)	NC score	0.196738 (rank : 89)
Query Neighborhood Hits	308	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

CCD46_HUMAN
θ value	0.0961366 (rank : 100)	NC score	0.049050 (rank : 339)
Query Neighborhood Hits	308	Target Neighborhood Hits	1430	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CING_HUMAN
θ value	0.0961366 (rank : 101)	NC score	0.056064 (rank : 306)
Query Neighborhood Hits	308	Target Neighborhood Hits	1275	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DLL3_HUMAN
θ value	0.0961366 (rank : 102)	NC score	0.112521 (rank : 130)
Query Neighborhood Hits	308	Target Neighborhood Hits	419	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

LCE2D_HUMAN
θ value	0.0961366 (rank : 103)	NC score	0.271302 (rank : 56)
Query Neighborhood Hits	308	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

TNR4_MOUSE
θ value	0.0961366 (rank : 104)	NC score	0.061925 (rank : 273)
Query Neighborhood Hits	308	Target Neighborhood Hits	137	Shared Neighborhood Hits	20
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

ERBB2_HUMAN
θ value	0.125558 (rank : 105)	NC score	0.059862 (rank : 282)
Query Neighborhood Hits	308	Target Neighborhood Hits	1073	Shared Neighborhood Hits	51
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

GOGA4_MOUSE
θ value	0.125558 (rank : 106)	NC score	0.045565 (rank : 355)
Query Neighborhood Hits	308	Target Neighborhood Hits	1939	Shared Neighborhood Hits	77
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

INSRR_MOUSE
θ value	0.125558 (rank : 107)	NC score	0.058720 (rank : 288)
Query Neighborhood Hits	308	Target Neighborhood Hits	961	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR171_HUMAN
θ value	0.125558 (rank : 108)	NC score	0.202640 (rank : 85)
Query Neighborhood Hits	308	Target Neighborhood Hits	144	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

CCD46_MOUSE
θ value	0.163984 (rank : 109)	NC score	0.047551 (rank : 344)
Query Neighborhood Hits	308	Target Neighborhood Hits	1405	Shared Neighborhood Hits	71
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

DLL3_MOUSE
θ value	0.163984 (rank : 110)	NC score	0.080848 (rank : 209)
Query Neighborhood Hits	308	Target Neighborhood Hits	399	Shared Neighborhood Hits	72
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DYH5_MOUSE
θ value	0.163984 (rank : 111)	NC score	0.055804 (rank : 307)
Query Neighborhood Hits	308	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

TRAF4_HUMAN
θ value	0.163984 (rank : 112)	NC score	0.035219 (rank : 392)
Query Neighborhood Hits	308	Target Neighborhood Hits	373	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

CCD41_HUMAN
θ value	0.21417 (rank : 113)	NC score	0.046205 (rank : 350)
Query Neighborhood Hits	308	Target Neighborhood Hits	1139	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

KRA31_HUMAN
θ value	0.21417 (rank : 114)	NC score	0.096638 (rank : 162)
Query Neighborhood Hits	308	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYR8	Gene names	KRTAP3-1, KAP3.1, KRTAP3.1
Domain Architecture
Description	Keratin-associated protein 3-1 (Keratin-associated protein 3.1) (High sulfur keratin-associated protein 3.1).

LCE2C_HUMAN
θ value	0.21417 (rank : 115)	NC score	0.265349 (rank : 60)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE5A_HUMAN
θ value	0.21417 (rank : 116)	NC score	0.264845 (rank : 62)
Query Neighborhood Hits	308	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

TRI26_HUMAN
θ value	0.279714 (rank : 117)	NC score	0.022488 (rank : 427)
Query Neighborhood Hits	308	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

UTRO_HUMAN
θ value	0.279714 (rank : 118)	NC score	0.047633 (rank : 343)
Query Neighborhood Hits	308	Target Neighborhood Hits	960	Shared Neighborhood Hits	65
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

HMCN1_HUMAN
θ value	0.365318 (rank : 119)	NC score	0.043896 (rank : 363)
Query Neighborhood Hits	308	Target Neighborhood Hits	983	Shared Neighborhood Hits	92
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KLC1_HUMAN
θ value	0.365318 (rank : 120)	NC score	0.034729 (rank : 394)
Query Neighborhood Hits	308	Target Neighborhood Hits	471	Shared Neighborhood Hits	49
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

NELFE_HUMAN
θ value	0.365318 (rank : 121)	NC score	0.047443 (rank : 345)
Query Neighborhood Hits	308	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

SMC1A_HUMAN
θ value	0.365318 (rank : 122)	NC score	0.049961 (rank : 336)
Query Neighborhood Hits	308	Target Neighborhood Hits	1346	Shared Neighborhood Hits	69
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.365318 (rank : 123)	NC score	0.048312 (rank : 341)
Query Neighborhood Hits	308	Target Neighborhood Hits	1384	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TRI26_MOUSE
θ value	0.365318 (rank : 124)	NC score	0.017929 (rank : 433)
Query Neighborhood Hits	308	Target Neighborhood Hits	339	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

VPS72_HUMAN
θ value	0.365318 (rank : 125)	NC score	0.040655 (rank : 375)
Query Neighborhood Hits	308	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CING_MOUSE
θ value	0.47712 (rank : 126)	NC score	0.044745 (rank : 360)
Query Neighborhood Hits	308	Target Neighborhood Hits	1432	Shared Neighborhood Hits	70
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

FBLN1_MOUSE
θ value	0.47712 (rank : 127)	NC score	0.062630 (rank : 270)
Query Neighborhood Hits	308	Target Neighborhood Hits	329	Shared Neighborhood Hits	65
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LTBP3_HUMAN
θ value	0.47712 (rank : 128)	NC score	0.089303 (rank : 180)
Query Neighborhood Hits	308	Target Neighborhood Hits	502	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TRIPB_HUMAN
θ value	0.47712 (rank : 129)	NC score	0.050463 (rank : 335)
Query Neighborhood Hits	308	Target Neighborhood Hits	1587	Shared Neighborhood Hits	71
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

BMPER_MOUSE
θ value	0.62314 (rank : 130)	NC score	0.172319 (rank : 99)
Query Neighborhood Hits	308	Target Neighborhood Hits	194	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CENPE_HUMAN
θ value	0.62314 (rank : 131)	NC score	0.033843 (rank : 399)
Query Neighborhood Hits	308	Target Neighborhood Hits	2060	Shared Neighborhood Hits	74
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CENPF_HUMAN
θ value	0.62314 (rank : 132)	NC score	0.046571 (rank : 347)
Query Neighborhood Hits	308	Target Neighborhood Hits	1932	Shared Neighborhood Hits	80
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DLL1_HUMAN
θ value	0.62314 (rank : 133)	NC score	0.096940 (rank : 161)
Query Neighborhood Hits	308	Target Neighborhood Hits	455	Shared Neighborhood Hits	99
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

EGF_HUMAN
θ value	0.62314 (rank : 134)	NC score	0.046290 (rank : 348)
Query Neighborhood Hits	308	Target Neighborhood Hits	343	Shared Neighborhood Hits	61
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

FBN3_HUMAN
θ value	0.62314 (rank : 135)	NC score	0.093976 (rank : 168)
Query Neighborhood Hits	308	Target Neighborhood Hits	543	Shared Neighborhood Hits	118
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LCE1B_HUMAN
θ value	0.62314 (rank : 136)	NC score	0.224533 (rank : 74)
Query Neighborhood Hits	308	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE2B_HUMAN
θ value	0.62314 (rank : 137)	NC score	0.225927 (rank : 73)
Query Neighborhood Hits	308	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

MA1A1_MOUSE
θ value	0.62314 (rank : 138)	NC score	0.016902 (rank : 435)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P45700	Gene names	Man1a1, Man1a
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

PUS7_HUMAN
θ value	0.62314 (rank : 139)	NC score	0.041965 (rank : 371)
Query Neighborhood Hits	308	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PZ0, Q75MG4, Q9NX19	Gene names	PUS7, KIAA1897
Domain Architecture
Description	Pseudouridylate synthase 7 homolog (EC 5.4.99.-).

SPR2A_MOUSE
θ value	0.62314 (rank : 140)	NC score	0.188757 (rank : 92)
Query Neighborhood Hits	308	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CQK8, O70553	Gene names	Sprr2a
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A.

SPR2B_HUMAN
θ value	0.62314 (rank : 141)	NC score	0.171006 (rank : 100)
Query Neighborhood Hits	308	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

ADA17_MOUSE
θ value	0.813845 (rank : 142)	NC score	0.077932 (rank : 223)
Query Neighborhood Hits	308	Target Neighborhood Hits	201	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

BMPER_HUMAN
θ value	0.813845 (rank : 143)	NC score	0.130136 (rank : 113)
Query Neighborhood Hits	308	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

C8AP2_MOUSE
θ value	0.813845 (rank : 144)	NC score	0.040276 (rank : 378)
Query Neighborhood Hits	308	Target Neighborhood Hits	405	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

DYH5_HUMAN
θ value	0.813845 (rank : 145)	NC score	0.055627 (rank : 309)
Query Neighborhood Hits	308	Target Neighborhood Hits	323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

GCC2_MOUSE
θ value	0.813845 (rank : 146)	NC score	0.043169 (rank : 366)
Query Neighborhood Hits	308	Target Neighborhood Hits	1619	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGB1_HUMAN
θ value	0.813845 (rank : 147)	NC score	0.048181 (rank : 342)
Query Neighborhood Hits	308	Target Neighborhood Hits	2297	Shared Neighborhood Hits	77
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LCE1E_HUMAN
θ value	0.813845 (rank : 148)	NC score	0.201399 (rank : 86)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

RAI14_HUMAN
θ value	0.813845 (rank : 149)	NC score	0.031512 (rank : 410)
Query Neighborhood Hits	308	Target Neighborhood Hits	1367	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RPTN_MOUSE
θ value	0.813845 (rank : 150)	NC score	0.026568 (rank : 420)
Query Neighborhood Hits	308	Target Neighborhood Hits	650	Shared Neighborhood Hits	19
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TIE1_HUMAN
θ value	0.813845 (rank : 151)	NC score	0.056753 (rank : 302)
Query Neighborhood Hits	308	Target Neighborhood Hits	1241	Shared Neighborhood Hits	97
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TRAF4_MOUSE
θ value	0.813845 (rank : 152)	NC score	0.032674 (rank : 403)
Query Neighborhood Hits	308	Target Neighborhood Hits	338	Shared Neighborhood Hits	6
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

UACA_MOUSE
θ value	0.813845 (rank : 153)	NC score	0.035610 (rank : 390)
Query Neighborhood Hits	308	Target Neighborhood Hits	1620	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

VPS72_MOUSE
θ value	0.813845 (rank : 154)	NC score	0.037047 (rank : 385)
Query Neighborhood Hits	308	Target Neighborhood Hits	286	Shared Neighborhood Hits	8
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ADA17_HUMAN
θ value	1.06291 (rank : 155)	NC score	0.075315 (rank : 230)
Query Neighborhood Hits	308	Target Neighborhood Hits	223	Shared Neighborhood Hits	56
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

CNOT3_HUMAN
θ value	1.06291 (rank : 156)	NC score	0.042838 (rank : 368)
Query Neighborhood Hits	308	Target Neighborhood Hits	425	Shared Neighborhood Hits	35
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	1.06291 (rank : 157)	NC score	0.045501 (rank : 356)
Query Neighborhood Hits	308	Target Neighborhood Hits	504	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CROCC_HUMAN
θ value	1.06291 (rank : 158)	NC score	0.045593 (rank : 354)
Query Neighborhood Hits	308	Target Neighborhood Hits	1409	Shared Neighborhood Hits	73
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GCC2_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.045339 (rank : 358)
Query Neighborhood Hits	308	Target Neighborhood Hits	1558	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

KR123_HUMAN
θ value	1.06291 (rank : 160)	NC score	0.367132 (rank : 39)
Query Neighborhood Hits	308	Target Neighborhood Hits	75	Shared Neighborhood Hits	58
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

LCE1C_HUMAN
θ value	1.06291 (rank : 161)	NC score	0.178244 (rank : 95)
Query Neighborhood Hits	308	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

RBP24_HUMAN
θ value	1.06291 (rank : 162)	NC score	0.045037 (rank : 359)
Query Neighborhood Hits	308	Target Neighborhood Hits	1559	Shared Neighborhood Hits	73
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SPR2D_HUMAN
θ value	1.06291 (rank : 163)	NC score	0.123298 (rank : 116)
Query Neighborhood Hits	308	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

STAB2_HUMAN
θ value	1.06291 (rank : 164)	NC score	0.114452 (rank : 126)
Query Neighborhood Hits	308	Target Neighborhood Hits	534	Shared Neighborhood Hits	119
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TCGAP_HUMAN
θ value	1.06291 (rank : 165)	NC score	0.013175 (rank : 445)
Query Neighborhood Hits	308	Target Neighborhood Hits	872	Shared Neighborhood Hits	15
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	1.06291 (rank : 166)	NC score	0.015493 (rank : 437)
Query Neighborhood Hits	308	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TSH1_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.010092 (rank : 450)
Query Neighborhood Hits	308	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

FBX18_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.038452 (rank : 383)
Query Neighborhood Hits	308	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FIP1_HUMAN
θ value	1.38821 (rank : 169)	NC score	0.066800 (rank : 248)
Query Neighborhood Hits	308	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

FIP1_MOUSE
θ value	1.38821 (rank : 170)	NC score	0.068302 (rank : 244)
Query Neighborhood Hits	308	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

GALT8_HUMAN
θ value	1.38821 (rank : 171)	NC score	0.007769 (rank : 457)
Query Neighborhood Hits	308	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY28	Gene names	GALNT8
Domain Architecture	No domain graphic available
Description	Probable polypeptide N-acetylgalactosaminyltransferase 8 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 8) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 8) (Polypeptide GalNAc transferase 8) (GalNAc-T8) (pp-GaNTase 8).

GPV_MOUSE
θ value	1.38821 (rank : 172)	NC score	0.002556 (rank : 462)
Query Neighborhood Hits	308	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

KLC1_MOUSE
θ value	1.38821 (rank : 173)	NC score	0.032018 (rank : 406)
Query Neighborhood Hits	308	Target Neighborhood Hits	357	Shared Neighborhood Hits	45
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

LTBP2_HUMAN
θ value	1.38821 (rank : 174)	NC score	0.085592 (rank : 193)
Query Neighborhood Hits	308	Target Neighborhood Hits	552	Shared Neighborhood Hits	100
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ODFP_HUMAN
θ value	1.38821 (rank : 175)	NC score	0.054321 (rank : 317)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

P5CS_MOUSE
θ value	1.38821 (rank : 176)	NC score	0.039314 (rank : 382)
Query Neighborhood Hits	308	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z110, Q9R1P6	Gene names	Aldh18a1, P5cs, Pycs
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

PEX6_HUMAN
θ value	1.38821 (rank : 177)	NC score	0.019892 (rank : 430)
Query Neighborhood Hits	308	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
θ value	1.38821 (rank : 178)	NC score	0.020474 (rank : 429)
Query Neighborhood Hits	308	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PIBF1_HUMAN
θ value	1.38821 (rank : 179)	NC score	0.042164 (rank : 370)
Query Neighborhood Hits	308	Target Neighborhood Hits	1041	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

RAD50_HUMAN
θ value	1.38821 (rank : 180)	NC score	0.046224 (rank : 349)
Query Neighborhood Hits	308	Target Neighborhood Hits	1317	Shared Neighborhood Hits	68
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

ROCK1_MOUSE
θ value	1.38821 (rank : 181)	NC score	0.020588 (rank : 428)
Query Neighborhood Hits	308	Target Neighborhood Hits	2126	Shared Neighborhood Hits	81
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SYNE1_HUMAN
θ value	1.38821 (rank : 182)	NC score	0.048777 (rank : 340)
Query Neighborhood Hits	308	Target Neighborhood Hits	1484	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TRAF5_MOUSE
θ value	1.38821 (rank : 183)	NC score	0.040090 (rank : 379)
Query Neighborhood Hits	308	Target Neighborhood Hits	355	Shared Neighborhood Hits	43
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

ADA24_MOUSE
θ value	1.81305 (rank : 184)	NC score	0.043623 (rank : 364)
Query Neighborhood Hits	308	Target Neighborhood Hits	230	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

CS029_MOUSE
θ value	1.81305 (rank : 185)	NC score	0.039641 (rank : 380)
Query Neighborhood Hits	308	Target Neighborhood Hits	201	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

EP15_MOUSE
θ value	1.81305 (rank : 186)	NC score	0.034222 (rank : 397)
Query Neighborhood Hits	308	Target Neighborhood Hits	820	Shared Neighborhood Hits	59
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FILA_HUMAN
θ value	1.81305 (rank : 187)	NC score	0.024506 (rank : 423)
Query Neighborhood Hits	308	Target Neighborhood Hits	685	Shared Neighborhood Hits	17
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LAMC2_MOUSE
θ value	1.81305 (rank : 188)	NC score	0.082493 (rank : 206)
Query Neighborhood Hits	308	Target Neighborhood Hits	614	Shared Neighborhood Hits	122
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LCE1D_HUMAN
θ value	1.81305 (rank : 189)	NC score	0.220085 (rank : 78)
Query Neighborhood Hits	308	Target Neighborhood Hits	44	Shared Neighborhood Hits	17
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LIPA2_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.045353 (rank : 357)
Query Neighborhood Hits	308	Target Neighborhood Hits	1044	Shared Neighborhood Hits	64
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LYPD1_HUMAN
θ value	1.81305 (rank : 191)	NC score	0.030284 (rank : 413)
Query Neighborhood Hits	308	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2G4, Q96AC2	Gene names	LYPD1, LYPDC1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

SIVA_MOUSE
θ value	1.81305 (rank : 192)	NC score	0.066263 (rank : 249)
Query Neighborhood Hits	308	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	O54926, Q3U6J2, Q921I8, Q9CWL1, Q9R1Q0, Q9R1Q1	Gene names	Siva
Domain Architecture
Description	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

SMC3_HUMAN
θ value	1.81305 (rank : 193)	NC score	0.052925 (rank : 321)
Query Neighborhood Hits	308	Target Neighborhood Hits	1186	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.052900 (rank : 322)
Query Neighborhood Hits	308	Target Neighborhood Hits	1187	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SPR1A_MOUSE
θ value	1.81305 (rank : 195)	NC score	0.107469 (rank : 139)
Query Neighborhood Hits	308	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR2A_HUMAN
θ value	1.81305 (rank : 196)	NC score	0.166114 (rank : 102)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P35326	Gene names	SPRR2A
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A (SPR-2A) (2-1).

TIE2_MOUSE
θ value	1.81305 (rank : 197)	NC score	0.047305 (rank : 346)
Query Neighborhood Hits	308	Target Neighborhood Hits	1204	Shared Neighborhood Hits	79
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

AD26A_MOUSE
θ value	2.36792 (rank : 198)	NC score	0.044659 (rank : 361)
Query Neighborhood Hits	308	Target Neighborhood Hits	165	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ATRN_MOUSE
θ value	2.36792 (rank : 199)	NC score	0.079411 (rank : 215)
Query Neighborhood Hits	308	Target Neighborhood Hits	519	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CRUM2_HUMAN
θ value	2.36792 (rank : 200)	NC score	0.088646 (rank : 182)
Query Neighborhood Hits	308	Target Neighborhood Hits	453	Shared Neighborhood Hits	96
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CT2NL_MOUSE
θ value	2.36792 (rank : 201)	NC score	0.031815 (rank : 407)
Query Neighborhood Hits	308	Target Neighborhood Hits	902	Shared Neighborhood Hits	54
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

EZH2_HUMAN
θ value	2.36792 (rank : 202)	NC score	0.045981 (rank : 352)
Query Neighborhood Hits	308	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	2.36792 (rank : 203)	NC score	0.046198 (rank : 351)
Query Neighborhood Hits	308	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

ILF2_HUMAN
θ value	2.36792 (rank : 204)	NC score	0.028432 (rank : 416)
Query Neighborhood Hits	308	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.028432 (rank : 417)
Query Neighborhood Hits	308	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ITB5_MOUSE
θ value	2.36792 (rank : 206)	NC score	0.078903 (rank : 220)
Query Neighborhood Hits	308	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NOTC2_HUMAN
θ value	2.36792 (rank : 207)	NC score	0.108387 (rank : 137)
Query Neighborhood Hits	308	Target Neighborhood Hits	1113	Shared Neighborhood Hits	145
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NSD1_HUMAN
θ value	2.36792 (rank : 208)	NC score	0.026252 (rank : 421)
Query Neighborhood Hits	308	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

UACA_HUMAN
θ value	2.36792 (rank : 209)	NC score	0.033816 (rank : 400)
Query Neighborhood Hits	308	Target Neighborhood Hits	1622	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AMGO3_MOUSE
θ value	3.0926 (rank : 210)	NC score	0.009526 (rank : 452)
Query Neighborhood Hits	308	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

BICD1_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.040402 (rank : 377)
Query Neighborhood Hits	308	Target Neighborhood Hits	844	Shared Neighborhood Hits	66
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

DNER_MOUSE
θ value	3.0926 (rank : 212)	NC score	0.084261 (rank : 200)
Query Neighborhood Hits	308	Target Neighborhood Hits	413	Shared Neighborhood Hits	81
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

E41L3_HUMAN
θ value	3.0926 (rank : 213)	NC score	0.007931 (rank : 455)
Query Neighborhood Hits	308	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

GOGA2_HUMAN
θ value	3.0926 (rank : 214)	NC score	0.040684 (rank : 374)
Query Neighborhood Hits	308	Target Neighborhood Hits	856	Shared Neighborhood Hits	60
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

JAG2_HUMAN
θ value	3.0926 (rank : 215)	NC score	0.102008 (rank : 150)
Query Neighborhood Hits	308	Target Neighborhood Hits	491	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KR122_HUMAN
θ value	3.0926 (rank : 216)	NC score	0.265120 (rank : 61)
Query Neighborhood Hits	308	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

LIPA2_MOUSE
θ value	3.0926 (rank : 217)	NC score	0.034021 (rank : 398)
Query Neighborhood Hits	308	Target Neighborhood Hits	1282	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LRC45_MOUSE
θ value	3.0926 (rank : 218)	NC score	0.034229 (rank : 396)
Query Neighborhood Hits	308	Target Neighborhood Hits	959	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NAGPA_MOUSE
θ value	3.0926 (rank : 219)	NC score	0.147737 (rank : 107)
Query Neighborhood Hits	308	Target Neighborhood Hits	308	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NHLC1_HUMAN
θ value	3.0926 (rank : 220)	NC score	0.023591 (rank : 424)
Query Neighborhood Hits	308	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NUMA1_HUMAN
θ value	3.0926 (rank : 221)	NC score	0.040653 (rank : 376)
Query Neighborhood Hits	308	Target Neighborhood Hits	1523	Shared Neighborhood Hits	65
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

P5CS_HUMAN
θ value	3.0926 (rank : 222)	NC score	0.032590 (rank : 404)
Query Neighborhood Hits	308	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P54886, O95952, Q9UM72	Gene names	ALDH18A1, P5CS, PYCS
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

RSPO4_MOUSE
θ value	3.0926 (rank : 223)	NC score	0.070879 (rank : 238)
Query Neighborhood Hits	308	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SPTB1_HUMAN
θ value	3.0926 (rank : 224)	NC score	0.029270 (rank : 414)
Query Neighborhood Hits	308	Target Neighborhood Hits	541	Shared Neighborhood Hits	52
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

STAT6_MOUSE
θ value	3.0926 (rank : 225)	NC score	0.008955 (rank : 454)
Query Neighborhood Hits	308	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

TNR3_MOUSE
θ value	3.0926 (rank : 226)	NC score	0.032157 (rank : 405)
Query Neighborhood Hits	308	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TR13B_HUMAN
θ value	3.0926 (rank : 227)	NC score	0.042773 (rank : 369)
Query Neighborhood Hits	308	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

TRBM_HUMAN
θ value	3.0926 (rank : 228)	NC score	0.087464 (rank : 185)
Query Neighborhood Hits	308	Target Neighborhood Hits	339	Shared Neighborhood Hits	79
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UN13B_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.006945 (rank : 459)
Query Neighborhood Hits	308	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UT14B_MOUSE
θ value	3.0926 (rank : 230)	NC score	0.033521 (rank : 402)
Query Neighborhood Hits	308	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

CCD45_MOUSE
θ value	4.03905 (rank : 231)	NC score	0.035928 (rank : 389)
Query Neighborhood Hits	308	Target Neighborhood Hits	663	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CK5P3_MOUSE
θ value	4.03905 (rank : 232)	NC score	0.019227 (rank : 431)
Query Neighborhood Hits	308	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LM2, Q3UE41	Gene names	Cdk5rap3
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3.

DGKE_MOUSE
θ value	4.03905 (rank : 233)	NC score	0.014489 (rank : 442)
Query Neighborhood Hits	308	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

EZH1_MOUSE
θ value	4.03905 (rank : 234)	NC score	0.054929 (rank : 312)
Query Neighborhood Hits	308	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FLIP1_MOUSE
θ value	4.03905 (rank : 235)	NC score	0.041225 (rank : 373)
Query Neighborhood Hits	308	Target Neighborhood Hits	1176	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

LAMA1_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.085149 (rank : 196)
Query Neighborhood Hits	308	Target Neighborhood Hits	804	Shared Neighborhood Hits	139
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LTB1L_MOUSE
θ value	4.03905 (rank : 237)	NC score	0.068533 (rank : 242)
Query Neighborhood Hits	308	Target Neighborhood Hits	514	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	4.03905 (rank : 238)	NC score	0.064381 (rank : 259)
Query Neighborhood Hits	308	Target Neighborhood Hits	479	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MYH3_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.030525 (rank : 412)
Query Neighborhood Hits	308	Target Neighborhood Hits	1660	Shared Neighborhood Hits	71
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NIN_MOUSE
θ value	4.03905 (rank : 240)	NC score	0.038128 (rank : 384)
Query Neighborhood Hits	308	Target Neighborhood Hits	1376	Shared Neighborhood Hits	64
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NOTC3_HUMAN
θ value	4.03905 (rank : 241)	NC score	0.110847 (rank : 133)
Query Neighborhood Hits	308	Target Neighborhood Hits	1062	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TRBM_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.088164 (rank : 184)
Query Neighborhood Hits	308	Target Neighborhood Hits	361	Shared Neighborhood Hits	92
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TXLNG_HUMAN
θ value	4.03905 (rank : 243)	NC score	0.033737 (rank : 401)
Query Neighborhood Hits	308	Target Neighborhood Hits	568	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

ADA12_MOUSE
θ value	5.27518 (rank : 244)	NC score	0.031758 (rank : 408)
Query Neighborhood Hits	308	Target Neighborhood Hits	474	Shared Neighborhood Hits	53
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA18_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.058924 (rank : 286)
Query Neighborhood Hits	308	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADAM7_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.031646 (rank : 409)
Query Neighborhood Hits	308	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADEC1_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.017373 (rank : 434)
Query Neighborhood Hits	308	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ATRN_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.070367 (rank : 240)
Query Neighborhood Hits	308	Target Neighborhood Hits	525	Shared Neighborhood Hits	80
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

CD248_MOUSE
θ value	5.27518 (rank : 249)	NC score	0.045780 (rank : 353)
Query Neighborhood Hits	308	Target Neighborhood Hits	578	Shared Neighborhood Hits	53
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DGUOK_MOUSE
θ value	5.27518 (rank : 250)	NC score	0.011208 (rank : 448)
Query Neighborhood Hits	308	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QX60, Q9R0Y2, Q9WUT9	Gene names	Dguok, Dgk
Domain Architecture
Description	Deoxyguanosine kinase, mitochondrial precursor (EC 2.7.1.113) (dGK).

DLK_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.098127 (rank : 157)
Query Neighborhood Hits	308	Target Neighborhood Hits	401	Shared Neighborhood Hits	94
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

FBLN4_HUMAN
θ value	5.27518 (rank : 252)	NC score	0.051374 (rank : 330)
Query Neighborhood Hits	308	Target Neighborhood Hits	278	Shared Neighborhood Hits	55
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	5.27518 (rank : 253)	NC score	0.051004 (rank : 333)
Query Neighborhood Hits	308	Target Neighborhood Hits	270	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FCER2_HUMAN
θ value	5.27518 (rank : 254)	NC score	0.007089 (rank : 458)
Query Neighborhood Hits	308	Target Neighborhood Hits	213	Shared Neighborhood Hits	18
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

LAMA5_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.122473 (rank : 117)
Query Neighborhood Hits	308	Target Neighborhood Hits	976	Shared Neighborhood Hits	159
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LIPA3_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.036699 (rank : 387)
Query Neighborhood Hits	308	Target Neighborhood Hits	828	Shared Neighborhood Hits	61
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MCF2_HUMAN
θ value	5.27518 (rank : 257)	NC score	0.009429 (rank : 453)
Query Neighborhood Hits	308	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MT4_MOUSE
θ value	5.27518 (rank : 258)	NC score	0.073238 (rank : 233)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NSD1_MOUSE
θ value	5.27518 (rank : 259)	NC score	0.027162 (rank : 418)
Query Neighborhood Hits	308	Target Neighborhood Hits	472	Shared Neighborhood Hits	25
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PCSK6_HUMAN
θ value	5.27518 (rank : 260)	NC score	0.112551 (rank : 129)
Query Neighborhood Hits	308	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PROS_MOUSE
θ value	5.27518 (rank : 261)	NC score	0.043202 (rank : 365)
Query Neighborhood Hits	308	Target Neighborhood Hits	330	Shared Neighborhood Hits	58
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SNIP1_HUMAN
θ value	5.27518 (rank : 262)	NC score	0.015331 (rank : 438)
Query Neighborhood Hits	308	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

SPTA1_MOUSE
θ value	5.27518 (rank : 263)	NC score	0.028945 (rank : 415)
Query Neighborhood Hits	308	Target Neighborhood Hits	675	Shared Neighborhood Hits	50
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TIE1_MOUSE
θ value	5.27518 (rank : 264)	NC score	0.053542 (rank : 320)
Query Neighborhood Hits	308	Target Neighborhood Hits	1266	Shared Neighborhood Hits	98
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR25_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.055473 (rank : 311)
Query Neighborhood Hits	308	Target Neighborhood Hits	172	Shared Neighborhood Hits	33
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ZGPAT_MOUSE
θ value	5.27518 (rank : 266)	NC score	0.014905 (rank : 441)
Query Neighborhood Hits	308	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

ZN592_HUMAN
θ value	5.27518 (rank : 267)	NC score	-0.000908 (rank : 464)
Query Neighborhood Hits	308	Target Neighborhood Hits	762	Shared Neighborhood Hits	5
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

ZN592_MOUSE
θ value	5.27518 (rank : 268)	NC score	-0.000544 (rank : 463)
Query Neighborhood Hits	308	Target Neighborhood Hits	768	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

BICD1_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.036235 (rank : 388)
Query Neighborhood Hits	308	Target Neighborhood Hits	837	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCD45_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.039529 (rank : 381)
Query Neighborhood Hits	308	Target Neighborhood Hits	525	Shared Neighborhood Hits	51
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CELR3_MOUSE
θ value	6.88961 (rank : 271)	NC score	0.041597 (rank : 372)
Query Neighborhood Hits	308	Target Neighborhood Hits	687	Shared Neighborhood Hits	94
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CUTL1_MOUSE
θ value	6.88961 (rank : 272)	NC score	0.026842 (rank : 419)
Query Neighborhood Hits	308	Target Neighborhood Hits	1620	Shared Neighborhood Hits	71
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

EHMT2_MOUSE
θ value	6.88961 (rank : 273)	NC score	0.010049 (rank : 451)
Query Neighborhood Hits	308	Target Neighborhood Hits	750	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EP15_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.030674 (rank : 411)
Query Neighborhood Hits	308	Target Neighborhood Hits	1021	Shared Neighborhood Hits	61
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EST1A_HUMAN
θ value	6.88961 (rank : 275)	NC score	0.035164 (rank : 393)
Query Neighborhood Hits	308	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

EST1A_MOUSE
θ value	6.88961 (rank : 276)	NC score	0.035452 (rank : 391)
Query Neighborhood Hits	308	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

EZH1_HUMAN
θ value	6.88961 (rank : 277)	NC score	0.049953 (rank : 337)
Query Neighborhood Hits	308	Target Neighborhood Hits	121	Shared Neighborhood Hits	39
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FANCG_MOUSE
θ value	6.88961 (rank : 278)	NC score	0.011986 (rank : 447)
Query Neighborhood Hits	308	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQR6	Gene names	Fancg
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein homolog (Protein FACG).

FHL2_MOUSE
θ value	6.88961 (rank : 279)	NC score	0.003738 (rank : 461)
Query Neighborhood Hits	308	Target Neighborhood Hits	539	Shared Neighborhood Hits	9
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

ITB2_MOUSE
θ value	6.88961 (rank : 280)	NC score	0.095381 (rank : 165)
Query Neighborhood Hits	308	Target Neighborhood Hits	326	Shared Neighborhood Hits	90
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KMHN1_MOUSE
θ value	6.88961 (rank : 281)	NC score	0.037018 (rank : 386)
Query Neighborhood Hits	308	Target Neighborhood Hits	949	Shared Neighborhood Hits	59
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LRP6_HUMAN
θ value	6.88961 (rank : 282)	NC score	0.023548 (rank : 425)
Query Neighborhood Hits	308	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LTBP3_MOUSE
θ value	6.88961 (rank : 283)	NC score	0.079201 (rank : 217)
Query Neighborhood Hits	308	Target Neighborhood Hits	475	Shared Neighborhood Hits	94
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC2_MOUSE
θ value	6.88961 (rank : 284)	NC score	0.099687 (rank : 154)
Query Neighborhood Hits	308	Target Neighborhood Hits	1069	Shared Neighborhood Hits	133
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PARP2_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.007930 (rank : 456)
Query Neighborhood Hits	308	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

RNUXA_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.013295 (rank : 444)
Query Neighborhood Hits	308	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H814, Q9H8W1	Gene names	RNUXA, PHAX
Domain Architecture	No domain graphic available
Description	RNA U small nuclear RNA export adapter protein (Phosphorylated adapter RNA export protein).

SEBP2_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.015493 (rank : 436)
Query Neighborhood Hits	308	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

SORL_MOUSE
θ value	6.88961 (rank : 288)	NC score	0.055525 (rank : 310)
Query Neighborhood Hits	308	Target Neighborhood Hits	439	Shared Neighborhood Hits	72
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TECTA_MOUSE
θ value	6.88961 (rank : 289)	NC score	0.100473 (rank : 151)
Query Neighborhood Hits	308	Target Neighborhood Hits	244	Shared Neighborhood Hits	82
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TIE2_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.043962 (rank : 362)
Query Neighborhood Hits	308	Target Neighborhood Hits	1192	Shared Neighborhood Hits	72
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ADA15_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.061379 (rank : 278)
Query Neighborhood Hits	308	Target Neighborhood Hits	288	Shared Neighborhood Hits	81
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

BRAP_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.025281 (rank : 422)
Query Neighborhood Hits	308	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

CP135_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.042918 (rank : 367)
Query Neighborhood Hits	308	Target Neighborhood Hits	1290	Shared Neighborhood Hits	71
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DNER_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.092175 (rank : 172)
Query Neighborhood Hits	308	Target Neighborhood Hits	460	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

EHMT2_HUMAN
θ value	8.99809 (rank : 295)	NC score	0.012010 (rank : 446)
Query Neighborhood Hits	308	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GPC5B_MOUSE
θ value	8.99809 (rank : 296)	NC score	0.005658 (rank : 460)
Query Neighborhood Hits	308	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

ITB8_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.066986 (rank : 247)
Query Neighborhood Hits	308	Target Neighborhood Hits	280	Shared Neighborhood Hits	72
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

K1H2_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.052596 (rank : 326)
Query Neighborhood Hits	308	Target Neighborhood Hits	492	Shared Neighborhood Hits	84
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

KR121_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.112015 (rank : 132)
Query Neighborhood Hits	308	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

LCE2A_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.163745 (rank : 103)
Query Neighborhood Hits	308	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

MKRN3_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.010928 (rank : 449)
Query Neighborhood Hits	308	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

PKCB1_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.013395 (rank : 443)
Query Neighborhood Hits	308	Target Neighborhood Hits	488	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RUVB1_HUMAN
θ value	8.99809 (rank : 303)	NC score	0.015050 (rank : 439)
Query Neighborhood Hits	308	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	8.99809 (rank : 304)	NC score	0.015048 (rank : 440)
Query Neighborhood Hits	308	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

SPR2K_MOUSE
θ value	8.99809 (rank : 305)	NC score	0.082706 (rank : 202)
Query Neighborhood Hits	308	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

TRI31_HUMAN
θ value	8.99809 (rank : 306)	NC score	0.019101 (rank : 432)
Query Neighborhood Hits	308	Target Neighborhood Hits	299	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TXLNB_MOUSE
θ value	8.99809 (rank : 307)	NC score	0.034434 (rank : 395)
Query Neighborhood Hits	308	Target Neighborhood Hits	640	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

WISP1_HUMAN
θ value	8.99809 (rank : 308)	NC score	0.023398 (rank : 426)
Query Neighborhood Hits	308	Target Neighborhood Hits	121	Shared Neighborhood Hits	20
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ADA10_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.052485 (rank : 327)
Query Neighborhood Hits	308	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.058795 (rank : 287)
Query Neighborhood Hits	308	Target Neighborhood Hits	194	Shared Neighborhood Hits	59
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA15_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.054407 (rank : 315)
Query Neighborhood Hits	308	Target Neighborhood Hits	324	Shared Neighborhood Hits	79
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADAM8_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.065572 (rank : 253)
Query Neighborhood Hits	308	Target Neighborhood Hits	327	Shared Neighborhood Hits	90
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.062367 (rank : 271)
Query Neighborhood Hits	308	Target Neighborhood Hits	326	Shared Neighborhood Hits	86
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

AGRIN_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.120042 (rank : 119)
Query Neighborhood Hits	308	Target Neighborhood Hits	582	Shared Neighborhood Hits	112
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

C1QR1_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.064205 (rank : 261)
Query Neighborhood Hits	308	Target Neighborhood Hits	493	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.053975 (rank : 318)
Query Neighborhood Hits	308	Target Neighborhood Hits	342	Shared Neighborhood Hits	71
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CHRD_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.058078 (rank : 294)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.053859 (rank : 319)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CP003_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.082590 (rank : 204)
Query Neighborhood Hits	308	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CRDL2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.058392 (rank : 290)
Query Neighborhood Hits	308	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.065545 (rank : 254)
Query Neighborhood Hits	308	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CREL1_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.094637 (rank : 167)
Query Neighborhood Hits	308	Target Neighborhood Hits	441	Shared Neighborhood Hits	77
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.091350 (rank : 174)
Query Neighborhood Hits	308	Target Neighborhood Hits	524	Shared Neighborhood Hits	80
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.204267 (rank : 83)
Query Neighborhood Hits	308	Target Neighborhood Hits	362	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.081737 (rank : 207)
Query Neighborhood Hits	308	Target Neighborhood Hits	457	Shared Neighborhood Hits	93
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.077224 (rank : 226)
Query Neighborhood Hits	308	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CUBN_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.056436 (rank : 303)
Query Neighborhood Hits	308	Target Neighborhood Hits	482	Shared Neighborhood Hits	81
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.054844 (rank : 313)
Query Neighborhood Hits	308	Target Neighborhood Hits	477	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CX048_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.088620 (rank : 183)
Query Neighborhood Hits	308	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

DLK_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.085641 (rank : 192)
Query Neighborhood Hits	308	Target Neighborhood Hits	374	Shared Neighborhood Hits	82
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.097921 (rank : 159)
Query Neighborhood Hits	308	Target Neighborhood Hits	456	Shared Neighborhood Hits	104
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL4_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.092805 (rank : 170)
Query Neighborhood Hits	308	Target Neighborhood Hits	435	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.095796 (rank : 163)
Query Neighborhood Hits	308	Target Neighborhood Hits	440	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EGFL7_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.063735 (rank : 264)
Query Neighborhood Hits	308	Target Neighborhood Hits	325	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.059472 (rank : 284)
Query Neighborhood Hits	308	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL9_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.079014 (rank : 219)
Query Neighborhood Hits	308	Target Neighborhood Hits	365	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.079752 (rank : 213)
Query Neighborhood Hits	308	Target Neighborhood Hits	379	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FBLN1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.058246 (rank : 292)
Query Neighborhood Hits	308	Target Neighborhood Hits	324	Shared Neighborhood Hits	66
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.066189 (rank : 250)
Query Neighborhood Hits	308	Target Neighborhood Hits	392	Shared Neighborhood Hits	73
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.057852 (rank : 297)
Query Neighborhood Hits	308	Target Neighborhood Hits	505	Shared Neighborhood Hits	78
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN5_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.057733 (rank : 298)
Query Neighborhood Hits	308	Target Neighborhood Hits	329	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.052811 (rank : 323)
Query Neighborhood Hits	308	Target Neighborhood Hits	317	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.103574 (rank : 148)
Query Neighborhood Hits	308	Target Neighborhood Hits	557	Shared Neighborhood Hits	123
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.105007 (rank : 144)
Query Neighborhood Hits	308	Target Neighborhood Hits	563	Shared Neighborhood Hits	123
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.106822 (rank : 141)
Query Neighborhood Hits	308	Target Neighborhood Hits	560	Shared Neighborhood Hits	121
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.105124 (rank : 143)
Query Neighborhood Hits	308	Target Neighborhood Hits	549	Shared Neighborhood Hits	122
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FSTL3_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.058089 (rank : 293)
Query Neighborhood Hits	308	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.071180 (rank : 236)
Query Neighborhood Hits	308	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.065987 (rank : 252)
Query Neighborhood Hits	308	Target Neighborhood Hits	146	Shared Neighborhood Hits	44
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GRN_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.196004 (rank : 90)
Query Neighborhood Hits	308	Target Neighborhood Hits	268	Shared Neighborhood Hits	105
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.173191 (rank : 97)
Query Neighborhood Hits	308	Target Neighborhood Hits	248	Shared Neighborhood Hits	99
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.104704 (rank : 145)
Query Neighborhood Hits	308	Target Neighborhood Hits	249	Shared Neighborhood Hits	81
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.061336 (rank : 279)
Query Neighborhood Hits	308	Target Neighborhood Hits	219	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

INSRR_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.052446 (rank : 328)
Query Neighborhood Hits	308	Target Neighborhood Hits	950	Shared Neighborhood Hits	68
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ITB1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.057456 (rank : 299)
Query Neighborhood Hits	308	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.070956 (rank : 237)
Query Neighborhood Hits	308	Target Neighborhood Hits	282	Shared Neighborhood Hits	73
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.078258 (rank : 222)
Query Neighborhood Hits	308	Target Neighborhood Hits	325	Shared Neighborhood Hits	86
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.075688 (rank : 229)
Query Neighborhood Hits	308	Target Neighborhood Hits	319	Shared Neighborhood Hits	81
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.066017 (rank : 251)
Query Neighborhood Hits	308	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.063152 (rank : 269)
Query Neighborhood Hits	308	Target Neighborhood Hits	318	Shared Neighborhood Hits	81
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.067277 (rank : 246)
Query Neighborhood Hits	308	Target Neighborhood Hits	341	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.064602 (rank : 258)
Query Neighborhood Hits	308	Target Neighborhood Hits	290	Shared Neighborhood Hits	71
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.060582 (rank : 280)
Query Neighborhood Hits	308	Target Neighborhood Hits	277	Shared Neighborhood Hits	66
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

JAG1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.104525 (rank : 146)
Query Neighborhood Hits	308	Target Neighborhood Hits	514	Shared Neighborhood Hits	113
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.104361 (rank : 147)
Query Neighborhood Hits	308	Target Neighborhood Hits	518	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.090500 (rank : 177)
Query Neighborhood Hits	308	Target Neighborhood Hits	504	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR111_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.317925 (rank : 45)
Query Neighborhood Hits	308	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR124_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.366136 (rank : 40)
Query Neighborhood Hits	308	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR131_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.220125 (rank : 77)
Query Neighborhood Hits	308	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.182589 (rank : 94)
Query Neighborhood Hits	308	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR133_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.151715 (rank : 106)
Query Neighborhood Hits	308	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.212879 (rank : 81)
Query Neighborhood Hits	308	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR151_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.060389 (rank : 281)
Query Neighborhood Hits	308	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	Q3LI76	Gene names	KRTAP15-1, KAP15.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 15-1.

KR241_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.086828 (rank : 188)
Query Neighborhood Hits	308	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR261_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.259801 (rank : 63)
Query Neighborhood Hits	308	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KRA15_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.183730 (rank : 93)
Query Neighborhood Hits	308	Target Neighborhood Hits	126	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA32_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.110716 (rank : 135)
Query Neighborhood Hits	308	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

KRA33_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.113335 (rank : 128)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

LAMA1_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.093927 (rank : 169)
Query Neighborhood Hits	308	Target Neighborhood Hits	838	Shared Neighborhood Hits	147
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.095117 (rank : 166)
Query Neighborhood Hits	308	Target Neighborhood Hits	1092	Shared Neighborhood Hits	153
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.092209 (rank : 171)
Query Neighborhood Hits	308	Target Neighborhood Hits	1198	Shared Neighborhood Hits	152
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.061619 (rank : 276)
Query Neighborhood Hits	308	Target Neighborhood Hits	760	Shared Neighborhood Hits	112
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.077889 (rank : 224)
Query Neighborhood Hits	308	Target Neighborhood Hits	859	Shared Neighborhood Hits	150
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.051250 (rank : 331)
Query Neighborhood Hits	308	Target Neighborhood Hits	708	Shared Neighborhood Hits	91
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.115992 (rank : 124)
Query Neighborhood Hits	308	Target Neighborhood Hits	828	Shared Neighborhood Hits	155
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.098767 (rank : 155)
Query Neighborhood Hits	308	Target Neighborhood Hits	1018	Shared Neighborhood Hits	154
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.085008 (rank : 197)
Query Neighborhood Hits	308	Target Neighborhood Hits	919	Shared Neighborhood Hits	137
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.088956 (rank : 181)
Query Neighborhood Hits	308	Target Neighborhood Hits	692	Shared Neighborhood Hits	127
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.091175 (rank : 175)
Query Neighborhood Hits	308	Target Neighborhood Hits	722	Shared Neighborhood Hits	134
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.074657 (rank : 231)
Query Neighborhood Hits	308	Target Neighborhood Hits	461	Shared Neighborhood Hits	104
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.085784 (rank : 191)
Query Neighborhood Hits	308	Target Neighborhood Hits	444	Shared Neighborhood Hits	103
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.079156 (rank : 218)
Query Neighborhood Hits	308	Target Neighborhood Hits	922	Shared Neighborhood Hits	150
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.076831 (rank : 227)
Query Neighborhood Hits	308	Target Neighborhood Hits	856	Shared Neighborhood Hits	137
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.073392 (rank : 232)
Query Neighborhood Hits	308	Target Neighborhood Hits	715	Shared Neighborhood Hits	117
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC3_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.089637 (rank : 179)
Query Neighborhood Hits	308	Target Neighborhood Hits	588	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.086288 (rank : 190)
Query Neighborhood Hits	308	Target Neighborhood Hits	624	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.132092 (rank : 110)
Query Neighborhood Hits	308	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1F_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.146210 (rank : 108)
Query Neighborhood Hits	308	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE3A_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.079577 (rank : 214)
Query Neighborhood Hits	308	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE4A_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.077463 (rank : 225)
Query Neighborhood Hits	308	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LDLR_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.058558 (rank : 289)
Query Neighborhood Hits	308	Target Neighborhood Hits	375	Shared Neighborhood Hits	85
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.063937 (rank : 263)
Query Neighborhood Hits	308	Target Neighborhood Hits	382	Shared Neighborhood Hits	84
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.080397 (rank : 210)
Query Neighborhood Hits	308	Target Neighborhood Hits	602	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.079250 (rank : 216)
Query Neighborhood Hits	308	Target Neighborhood Hits	606	Shared Neighborhood Hits	119
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.097947 (rank : 158)
Query Neighborhood Hits	308	Target Neighborhood Hits	617	Shared Neighborhood Hits	127
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.084414 (rank : 198)
Query Neighborhood Hits	308	Target Neighborhood Hits	573	Shared Neighborhood Hits	113
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTB1L_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.068304 (rank : 243)
Query Neighborhood Hits	308	Target Neighborhood Hits	553	Shared Neighborhood Hits	93
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.064257 (rank : 260)
Query Neighborhood Hits	308	Target Neighborhood Hits	502	Shared Neighborhood Hits	79
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.078832 (rank : 221)
Query Neighborhood Hits	308	Target Neighborhood Hits	617	Shared Neighborhood Hits	99
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP4_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.091142 (rank : 176)
Query Neighborhood Hits	308	Target Neighborhood Hits	607	Shared Neighborhood Hits	98
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MATN2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.058017 (rank : 295)
Query Neighborhood Hits	308	Target Neighborhood Hits	365	Shared Neighborhood Hits	63
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.062050 (rank : 272)
Query Neighborhood Hits	308	Target Neighborhood Hits	356	Shared Neighborhood Hits	71
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MCSP_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.052680 (rank : 324)
Query Neighborhood Hits	308	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF8_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.100037 (rank : 152)
Query Neighborhood Hits	308	Target Neighborhood Hits	528	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.087354 (rank : 186)
Query Neighborhood Hits	308	Target Neighborhood Hits	520	Shared Neighborhood Hits	97
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.099979 (rank : 153)
Query Neighborhood Hits	308	Target Neighborhood Hits	557	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.082655 (rank : 203)
Query Neighborhood Hits	308	Target Neighborhood Hits	896	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MT3_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.058354 (rank : 291)
Query Neighborhood Hits	308	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MUC2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.106172 (rank : 142)
Query Neighborhood Hits	308	Target Neighborhood Hits	906	Shared Neighborhood Hits	82
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NAGPA_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.121457 (rank : 118)
Query Neighborhood Hits	308	Target Neighborhood Hits	282	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.092131 (rank : 173)
Query Neighborhood Hits	308	Target Neighborhood Hits	451	Shared Neighborhood Hits	105
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.081267 (rank : 208)
Query Neighborhood Hits	308	Target Neighborhood Hits	449	Shared Neighborhood Hits	91
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.087050 (rank : 187)
Query Neighborhood Hits	308	Target Neighborhood Hits	436	Shared Neighborhood Hits	91
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.102785 (rank : 149)
Query Neighborhood Hits	308	Target Neighborhood Hits	906	Shared Neighborhood Hits	129
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.108478 (rank : 136)
Query Neighborhood Hits	308	Target Neighborhood Hits	916	Shared Neighborhood Hits	131
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.115926 (rank : 125)
Query Neighborhood Hits	308	Target Neighborhood Hits	975	Shared Neighborhood Hits	135
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.107475 (rank : 138)
Query Neighborhood Hits	308	Target Neighborhood Hits	905	Shared Neighborhood Hits	135
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.107264 (rank : 140)
Query Neighborhood Hits	308	Target Neighborhood Hits	872	Shared Neighborhood Hits	132
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

RECK_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.095690 (rank : 164)
Query Neighborhood Hits	308	Target Neighborhood Hits	189	Shared Neighborhood Hits	47
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.090060 (rank : 178)
Query Neighborhood Hits	308	Target Neighborhood Hits	158	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RSPO3_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.057231 (rank : 300)
Query Neighborhood Hits	308	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.056130 (rank : 305)
Query Neighborhood Hits	308	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.057947 (rank : 296)
Query Neighborhood Hits	308	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.059844 (rank : 283)
Query Neighborhood Hits	308	Target Neighborhood Hits	428	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.064010 (rank : 262)
Query Neighborhood Hits	308	Target Neighborhood Hits	442	Shared Neighborhood Hits	81
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.056412 (rank : 304)
Query Neighborhood Hits	308	Target Neighborhood Hits	700	Shared Neighborhood Hits	90
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.050925 (rank : 334)
Query Neighborhood Hits	308	Target Neighborhood Hits	715	Shared Neighborhood Hits	102
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT3_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.061766 (rank : 274)
Query Neighborhood Hits	308	Target Neighborhood Hits	700	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SPR1A_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.084373 (rank : 199)
Query Neighborhood Hits	308	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPR1B_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.082571 (rank : 205)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	23
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SPR1B_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.065121 (rank : 255)
Query Neighborhood Hits	308	Target Neighborhood Hits	395	Shared Neighborhood Hits	30
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPR2J_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.086464 (rank : 189)
Query Neighborhood Hits	308	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	O70561	Gene names	Sprr2j
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2J.

STAB1_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.124061 (rank : 115)
Query Neighborhood Hits	308	Target Neighborhood Hits	546	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.130152 (rank : 112)
Query Neighborhood Hits	308	Target Neighborhood Hits	566	Shared Neighborhood Hits	129
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.110724 (rank : 134)
Query Neighborhood Hits	308	Target Neighborhood Hits	528	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TECTA_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.098692 (rank : 156)
Query Neighborhood Hits	308	Target Neighborhood Hits	239	Shared Neighborhood Hits	79
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TENA_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.118066 (rank : 121)
Query Neighborhood Hits	308	Target Neighborhood Hits	596	Shared Neighborhood Hits	110
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.052600 (rank : 325)
Query Neighborhood Hits	308	Target Neighborhood Hits	453	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.065082 (rank : 256)
Query Neighborhood Hits	308	Target Neighborhood Hits	484	Shared Neighborhood Hits	94
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.085433 (rank : 195)
Query Neighborhood Hits	308	Target Neighborhood Hits	526	Shared Neighborhood Hits	102
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.085468 (rank : 194)
Query Neighborhood Hits	308	Target Neighborhood Hits	531	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.119865 (rank : 120)
Query Neighborhood Hits	308	Target Neighborhood Hits	789	Shared Neighborhood Hits	117
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TNR8_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.054404 (rank : 316)
Query Neighborhood Hits	308	Target Neighborhood Hits	208	Shared Neighborhood Hits	39
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TRI42_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.083079 (rank : 201)
Query Neighborhood Hits	308	Target Neighborhood Hits	316	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TSP1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.051176 (rank : 332)
Query Neighborhood Hits	308	Target Neighborhood Hits	389	Shared Neighborhood Hits	76
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.056829 (rank : 301)
Query Neighborhood Hits	308	Target Neighborhood Hits	359	Shared Neighborhood Hits	86
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.052034 (rank : 329)
Query Neighborhood Hits	308	Target Neighborhood Hits	352	Shared Neighborhood Hits	80
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

USH2A_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.067902 (rank : 245)
Query Neighborhood Hits	308	Target Neighborhood Hits	600	Shared Neighborhood Hits	84
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.097447 (rank : 160)
Query Neighborhood Hits	308	Target Neighborhood Hits	626	Shared Neighborhood Hits	112
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VLDLR_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.058949 (rank : 285)
Query Neighborhood Hits	308	Target Neighborhood Hits	383	Shared Neighborhood Hits	77
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WFDC2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.113914 (rank : 127)
Query Neighborhood Hits	308	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

WFDC5_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.063161 (rank : 268)
Query Neighborhood Hits	308	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

WIF1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.129951 (rank : 114)
Query Neighborhood Hits	308	Target Neighborhood Hits	392	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.131682 (rank : 111)
Query Neighborhood Hits	308	Target Neighborhood Hits	393	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

ZNFX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	308	Target Neighborhood Hits	308	Shared Neighborhood Hits	308
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
NC score	0.959028 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	308	Target Neighborhood Hits	407	Shared Neighborhood Hits	220
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

RENT1_HUMAN
NC score	0.567569 (rank : 3)	θ value	4.42448e-31 (rank : 3)
Query Neighborhood Hits	308	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
NC score	0.567191 (rank : 4)	θ value	5.77852e-31 (rank : 4)
Query Neighborhood Hits	308	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

AQR_MOUSE
NC score	0.521767 (rank : 5)	θ value	2.27234e-27 (rank : 6)
Query Neighborhood Hits	308	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.520763 (rank : 6)	θ value	2.27234e-27 (rank : 5)
Query Neighborhood Hits	308	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

NFX1_HUMAN
NC score	0.476793 (rank : 7)	θ value	2.13179e-17 (rank : 8)
Query Neighborhood Hits	308	Target Neighborhood Hits	405	Shared Neighborhood Hits	104
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

SETX_HUMAN
NC score	0.473584 (rank : 8)	θ value	7.32683e-18 (rank : 7)
Query Neighborhood Hits	308	Target Neighborhood Hits	368	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SMBP2_MOUSE
NC score	0.472511 (rank : 9)	θ value	5.43371e-13 (rank : 11)
Query Neighborhood Hits	308	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMBP2_HUMAN
NC score	0.471664 (rank : 10)	θ value	5.43371e-13 (rank : 10)
Query Neighborhood Hits	308	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

PR285_HUMAN
NC score	0.460263 (rank : 11)	θ value	1.29331e-14 (rank : 9)
Query Neighborhood Hits	308	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

KRA24_HUMAN
NC score	0.451834 (rank : 12)	θ value	0.0148317 (rank : 82)
Query Neighborhood Hits	308	Target Neighborhood Hits	192	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KR10A_HUMAN
NC score	0.448714 (rank : 13)	θ value	2.36244e-08 (rank : 25)
Query Neighborhood Hits	308	Target Neighborhood Hits	232	Shared Neighborhood Hits	90
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR105_HUMAN
NC score	0.438679 (rank : 14)	θ value	3.08544e-08 (rank : 26)
Query Neighborhood Hits	308	Target Neighborhood Hits	271	Shared Neighborhood Hits	103
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR10B_HUMAN
NC score	0.438460 (rank : 15)	θ value	8.97725e-08 (rank : 28)
Query Neighborhood Hits	308	Target Neighborhood Hits	269	Shared Neighborhood Hits	103
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR103_HUMAN
NC score	0.436171 (rank : 16)	θ value	4.1701e-05 (rank : 53)
Query Neighborhood Hits	308	Target Neighborhood Hits	212	Shared Neighborhood Hits	100
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

M10L1_HUMAN
NC score	0.421412 (rank : 17)	θ value	2.28291e-11 (rank : 13)
Query Neighborhood Hits	308	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

KRA94_HUMAN
NC score	0.418661 (rank : 18)	θ value	4.45536e-07 (rank : 37)
Query Neighborhood Hits	308	Target Neighborhood Hits	204	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MOV10_MOUSE
NC score	0.417421 (rank : 19)	θ value	5.62301e-10 (rank : 16)
Query Neighborhood Hits	308	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_HUMAN
NC score	0.417419 (rank : 20)	θ value	7.34386e-10 (rank : 18)
Query Neighborhood Hits	308	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

KR106_HUMAN
NC score	0.416723 (rank : 21)	θ value	2.69671e-12 (rank : 12)
Query Neighborhood Hits	308	Target Neighborhood Hits	347	Shared Neighborhood Hits	117
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

M10L1_MOUSE
NC score	0.408459 (rank : 22)	θ value	7.34386e-10 (rank : 17)
Query Neighborhood Hits	308	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

KRA98_HUMAN
NC score	0.406968 (rank : 23)	θ value	6.21693e-09 (rank : 22)
Query Neighborhood Hits	308	Target Neighborhood Hits	185	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
NC score	0.404792 (rank : 24)	θ value	8.97725e-08 (rank : 30)
Query Neighborhood Hits	308	Target Neighborhood Hits	173	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KRA92_HUMAN
NC score	0.404779 (rank : 25)	θ value	1.53129e-07 (rank : 32)
Query Neighborhood Hits	308	Target Neighborhood Hits	198	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA47_HUMAN
NC score	0.403271 (rank : 26)	θ value	1.17247e-07 (rank : 31)
Query Neighborhood Hits	308	Target Neighborhood Hits	204	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KR412_HUMAN
NC score	0.399768 (rank : 27)	θ value	8.97725e-08 (rank : 29)
Query Neighborhood Hits	308	Target Neighborhood Hits	178	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA42_HUMAN
NC score	0.399656 (rank : 28)	θ value	0.00134147 (rank : 65)
Query Neighborhood Hits	308	Target Neighborhood Hits	149	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA45_HUMAN
NC score	0.398885 (rank : 29)	θ value	3.41135e-07 (rank : 35)
Query Neighborhood Hits	308	Target Neighborhood Hits	194	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KR107_HUMAN
NC score	0.396845 (rank : 30)	θ value	2.98157e-11 (rank : 14)
Query Neighborhood Hits	308	Target Neighborhood Hits	330	Shared Neighborhood Hits	116
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

HELZ_HUMAN
NC score	0.390234 (rank : 31)	θ value	1.06045e-08 (rank : 23)
Query Neighborhood Hits	308	Target Neighborhood Hits	198	Shared Neighborhood Hits	17
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

KRA93_HUMAN
NC score	0.388839 (rank : 32)	θ value	4.45536e-07 (rank : 36)
Query Neighborhood Hits	308	Target Neighborhood Hits	203	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KR109_HUMAN
NC score	0.386338 (rank : 33)	θ value	1.63604e-09 (rank : 20)
Query Neighborhood Hits	308	Target Neighborhood Hits	226	Shared Neighborhood Hits	85
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR410_HUMAN
NC score	0.385535 (rank : 34)	θ value	0.00175202 (rank : 67)
Query Neighborhood Hits	308	Target Neighborhood Hits	156	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR102_HUMAN
NC score	0.380675 (rank : 35)	θ value	3.41135e-07 (rank : 34)
Query Neighborhood Hits	308	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR10C_HUMAN
NC score	0.372210 (rank : 36)	θ value	5.81887e-07 (rank : 38)
Query Neighborhood Hits	308	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR108_HUMAN
NC score	0.370067 (rank : 37)	θ value	6.87365e-08 (rank : 27)
Query Neighborhood Hits	308	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR101_HUMAN
NC score	0.369154 (rank : 38)	θ value	1.63604e-09 (rank : 19)
Query Neighborhood Hits	308	Target Neighborhood Hits	261	Shared Neighborhood Hits	86
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR123_HUMAN
NC score	0.367132 (rank : 39)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	308	Target Neighborhood Hits	75	Shared Neighborhood Hits	58
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR124_HUMAN
NC score	0.366136 (rank : 40)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	308	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR414_HUMAN
NC score	0.366109 (rank : 41)	θ value	6.43352e-06 (rank : 42)
Query Neighborhood Hits	308	Target Neighborhood Hits	199	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA44_HUMAN
NC score	0.350473 (rank : 42)	θ value	3.19293e-05 (rank : 52)
Query Neighborhood Hits	308	Target Neighborhood Hits	162	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KR104_HUMAN
NC score	0.341837 (rank : 43)	θ value	8.67504e-11 (rank : 15)
Query Neighborhood Hits	308	Target Neighborhood Hits	313	Shared Neighborhood Hits	88
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR413_HUMAN
NC score	0.334741 (rank : 44)	θ value	0.0193708 (rank : 85)
Query Neighborhood Hits	308	Target Neighborhood Hits	112	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR111_HUMAN
NC score	0.317925 (rank : 45)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	308	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

SPR2D_MOUSE
NC score	0.314879 (rank : 46)	θ value	1.43324e-05 (rank : 48)
Query Neighborhood Hits	308	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2B_MOUSE
NC score	0.301105 (rank : 47)	θ value	1.09739e-05 (rank : 46)
Query Neighborhood Hits	308	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2F_HUMAN
NC score	0.295722 (rank : 48)	θ value	0.00175202 (rank : 68)
Query Neighborhood Hits	308	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
NC score	0.295067 (rank : 49)	θ value	0.000121331 (rank : 57)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

KR511_HUMAN
NC score	0.289830 (rank : 50)	θ value	1.87187e-05 (rank : 49)
Query Neighborhood Hits	308	Target Neighborhood Hits	231	Shared Neighborhood Hits	66
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

WFDC3_HUMAN
NC score	0.287312 (rank : 51)	θ value	0.0193708 (rank : 87)
Query Neighborhood Hits	308	Target Neighborhood Hits	138	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

SPR2H_MOUSE
NC score	0.282567 (rank : 52)	θ value	8.40245e-06 (rank : 44)
Query Neighborhood Hits	308	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SREC_HUMAN
NC score	0.278329 (rank : 53)	θ value	2.13673e-09 (rank : 21)
Query Neighborhood Hits	308	Target Neighborhood Hits	645	Shared Neighborhood Hits	149
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KR510_HUMAN
NC score	0.272747 (rank : 54)	θ value	0.000270298 (rank : 60)
Query Neighborhood Hits	308	Target Neighborhood Hits	217	Shared Neighborhood Hits	65
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA53_HUMAN
NC score	0.272098 (rank : 55)	θ value	1.06045e-08 (rank : 24)
Query Neighborhood Hits	308	Target Neighborhood Hits	331	Shared Neighborhood Hits	98
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LCE2D_HUMAN
NC score	0.271302 (rank : 56)	θ value	0.0961366 (rank : 103)
Query Neighborhood Hits	308	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

KRA55_HUMAN
NC score	0.271283 (rank : 57)	θ value	1.87187e-05 (rank : 50)
Query Neighborhood Hits	308	Target Neighborhood Hits	257	Shared Neighborhood Hits	76
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA58_HUMAN
NC score	0.270825 (rank : 58)	θ value	9.92553e-07 (rank : 40)
Query Neighborhood Hits	308	Target Neighborhood Hits	324	Shared Neighborhood Hits	97
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SPR2E_HUMAN
NC score	0.267415 (rank : 59)	θ value	0.00298849 (rank : 71)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

LCE2C_HUMAN
NC score	0.265349 (rank : 60)	θ value	0.21417 (rank : 115)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

KR122_HUMAN
NC score	0.265120 (rank : 61)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	308	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

LCE5A_HUMAN
NC score	0.264845 (rank : 62)	θ value	0.21417 (rank : 116)
Query Neighborhood Hits	308	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

KR261_HUMAN
NC score	0.259801 (rank : 63)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	308	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KRA54_HUMAN
NC score	0.258820 (rank : 64)	θ value	0.000461057 (rank : 64)
Query Neighborhood Hits	308	Target Neighborhood Hits	270	Shared Neighborhood Hits	76
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA57_HUMAN
NC score	0.258366 (rank : 65)	θ value	0.000158464 (rank : 58)
Query Neighborhood Hits	308	Target Neighborhood Hits	269	Shared Neighborhood Hits	81
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA13_HUMAN
NC score	0.255065 (rank : 66)	θ value	0.0148317 (rank : 81)
Query Neighborhood Hits	308	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA52_HUMAN
NC score	0.252812 (rank : 67)	θ value	0.00869519 (rank : 78)
Query Neighborhood Hits	308	Target Neighborhood Hits	236	Shared Neighborhood Hits	75
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

SPR2I_MOUSE
NC score	0.251439 (rank : 68)	θ value	0.00665767 (rank : 77)
Query Neighborhood Hits	308	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SPR2E_MOUSE
NC score	0.249971 (rank : 69)	θ value	0.0148317 (rank : 83)
Query Neighborhood Hits	308	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

KRA59_HUMAN
NC score	0.249702 (rank : 70)	θ value	1.09739e-05 (rank : 45)
Query Neighborhood Hits	308	Target Neighborhood Hits	310	Shared Neighborhood Hits	79
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

FRAS1_MOUSE
NC score	0.247629 (rank : 71)	θ value	2.88788e-06 (rank : 41)
Query Neighborhood Hits	308	Target Neighborhood Hits	747	Shared Neighborhood Hits	140
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_HUMAN
NC score	0.237447 (rank : 72)	θ value	3.19293e-05 (rank : 51)
Query Neighborhood Hits	308	Target Neighborhood Hits	759	Shared Neighborhood Hits	135
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LCE2B_HUMAN
NC score	0.225927 (rank : 73)	θ value	0.62314 (rank : 137)
Query Neighborhood Hits	308	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE1B_HUMAN
NC score	0.224533 (rank : 74)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	308	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MCSP_MOUSE
NC score	0.222310 (rank : 75)	θ value	0.00665767 (rank : 76)
Query Neighborhood Hits	308	Target Neighborhood Hits	108	Shared Neighborhood Hits	35
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SREC2_MOUSE
NC score	0.222297 (rank : 76)	θ value	1.53129e-07 (rank : 33)
Query Neighborhood Hits	308	Target Neighborhood Hits	605	Shared Neighborhood Hits	133
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KR131_HUMAN
NC score	0.220125 (rank : 77)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	308	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

LCE1D_HUMAN
NC score	0.220085 (rank : 78)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	308	Target Neighborhood Hits	44	Shared Neighborhood Hits	17
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

ZAN_MOUSE
NC score	0.215972 (rank : 79)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	308	Target Neighborhood Hits	808	Shared Neighborhood Hits	160
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SREC2_HUMAN
NC score	0.214715 (rank : 80)	θ value	0.00035302 (rank : 63)
Query Neighborhood Hits	308	Target Neighborhood Hits	645	Shared Neighborhood Hits	132
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

KR134_HUMAN
NC score	0.212879 (rank : 81)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	308	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KRA11_HUMAN
NC score	0.209193 (rank : 82)	θ value	0.0148317 (rank : 80)
Query Neighborhood Hits	308	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

CRIM1_HUMAN
NC score	0.204267 (rank : 83)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	308	Target Neighborhood Hits	362	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

MUC5B_HUMAN
NC score	0.203889 (rank : 84)	θ value	0.0563607 (rank : 95)
Query Neighborhood Hits	308	Target Neighborhood Hits	1020	Shared Neighborhood Hits	138
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KR171_HUMAN
NC score	0.202640 (rank : 85)	θ value	0.125558 (rank : 108)
Query Neighborhood Hits	308	Target Neighborhood Hits	144	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LCE1E_HUMAN
NC score	0.201399 (rank : 86)	θ value	0.813845 (rank : 148)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

KRA51_HUMAN
NC score	0.200829 (rank : 87)	θ value	9.29e-05 (rank : 56)
Query Neighborhood Hits	308	Target Neighborhood Hits	288	Shared Neighborhood Hits	71
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

PCSK5_MOUSE
NC score	0.200218 (rank : 88)	θ value	5.81887e-07 (rank : 39)
Query Neighborhood Hits	308	Target Neighborhood Hits	613	Shared Neighborhood Hits	132
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

SPR2F_MOUSE
NC score	0.196738 (rank : 89)	θ value	0.0736092 (rank : 99)
Query Neighborhood Hits	308	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

GRN_HUMAN
NC score	0.196004 (rank : 90)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	308	Target Neighborhood Hits	268	Shared Neighborhood Hits	105
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA56_HUMAN
NC score	0.194114 (rank : 91)	θ value	0.0736092 (rank : 98)
Query Neighborhood Hits	308	Target Neighborhood Hits	207	Shared Neighborhood Hits	62
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

SPR2A_MOUSE
NC score	0.188757 (rank : 92)	θ value	0.62314 (rank : 140)
Query Neighborhood Hits	308	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CQK8, O70553	Gene names	Sprr2a
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A.

KRA15_HUMAN
NC score	0.183730 (rank : 93)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	308	Target Neighborhood Hits	126	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KR132_HUMAN
NC score	0.182589 (rank : 94)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	308	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

LCE1C_HUMAN
NC score	0.178244 (rank : 95)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	308	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

VWF_HUMAN
NC score	0.177711 (rank : 96)	θ value	0.0193708 (rank : 86)
Query Neighborhood Hits	308	Target Neighborhood Hits	396	Shared Neighborhood Hits	113
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GRN_MOUSE
NC score	0.173191 (rank : 97)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	308	Target Neighborhood Hits	248	Shared Neighborhood Hits	99
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

MEGF6_HUMAN
NC score	0.172481 (rank : 98)	θ value	7.1131e-05 (rank : 54)
Query Neighborhood Hits	308	Target Neighborhood Hits	671	Shared Neighborhood Hits	155
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

BMPER_MOUSE
NC score	0.172319 (rank : 99)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	308	Target Neighborhood Hits	194	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

SPR2B_HUMAN
NC score	0.171006 (rank : 100)	θ value	0.62314 (rank : 141)
Query Neighborhood Hits	308	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

VWF_MOUSE
NC score	0.169682 (rank : 101)	θ value	0.00134147 (rank : 66)
Query Neighborhood Hits	308	Target Neighborhood Hits	381	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

SPR2A_HUMAN
NC score	0.166114 (rank : 102)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P35326	Gene names	SPRR2A
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A (SPR-2A) (2-1).

LCE2A_HUMAN
NC score	0.163745 (rank : 103)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	308	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

ZAN_HUMAN
NC score	0.161529 (rank : 104)	θ value	0.00228821 (rank : 70)
Query Neighborhood Hits	308	Target Neighborhood Hits	679	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SSPO_MOUSE
NC score	0.152418 (rank : 105)	θ value	0.00175202 (rank : 69)
Query Neighborhood Hits	308	Target Neighborhood Hits	800	Shared Neighborhood Hits	145
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KR133_HUMAN
NC score	0.151715 (rank : 106)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	308	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

NAGPA_MOUSE
NC score	0.147737 (rank : 107)	θ value	3.0926 (rank : 219)
Query Neighborhood Hits	308	Target Neighborhood Hits	308	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LCE1F_HUMAN
NC score	0.146210 (rank : 108)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	308	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

TENA_HUMAN
NC score	0.141852 (rank : 109)	θ value	0.00390308 (rank : 72)
Query Neighborhood Hits	308	Target Neighborhood Hits	631	Shared Neighborhood Hits	115
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LCE1A_HUMAN
NC score	0.132092 (rank : 110)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	308	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

WIF1_MOUSE
NC score	0.131682 (rank : 111)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	308	Target Neighborhood Hits	393	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

STAB1_MOUSE
NC score	0.130152 (rank : 112)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	308	Target Neighborhood Hits	566	Shared Neighborhood Hits	129
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

BMPER_HUMAN
NC score	0.130136 (rank : 113)	θ value	0.813845 (rank : 143)
Query Neighborhood Hits	308	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

WIF1_HUMAN
NC score	0.129951 (rank : 114)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	308	Target Neighborhood Hits	392	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

STAB1_HUMAN
NC score	0.124061 (rank : 115)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	308	Target Neighborhood Hits	546	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

SPR2D_HUMAN
NC score	0.123298 (rank : 116)	θ value	1.06291 (rank : 163)
Query Neighborhood Hits	308	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

LAMA5_HUMAN
NC score	0.122473 (rank : 117)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	308	Target Neighborhood Hits	976	Shared Neighborhood Hits	159
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NAGPA_HUMAN
NC score	0.121457 (rank : 118)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	308	Target Neighborhood Hits	282	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

AGRIN_HUMAN
NC score	0.120042 (rank : 119)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	308	Target Neighborhood Hits	582	Shared Neighborhood Hits	112
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

TENX_HUMAN
NC score	0.119865 (rank : 120)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	308	Target Neighborhood Hits	789	Shared Neighborhood Hits	117
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TENA_MOUSE
NC score	0.118066 (rank : 121)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	308	Target Neighborhood Hits	596	Shared Neighborhood Hits	110
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MYCB2_MOUSE
NC score	0.117762 (rank : 122)	θ value	0.000270298 (rank : 62)
Query Neighborhood Hits	308	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_HUMAN
NC score	0.116699 (rank : 123)	θ value	0.000270298 (rank : 61)
Query Neighborhood Hits	308	Target Neighborhood Hits	390	Shared Neighborhood Hits	22
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

LAMA5_MOUSE
NC score	0.115992 (rank : 124)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	308	Target Neighborhood Hits	828	Shared Neighborhood Hits	155
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC3_MOUSE
NC score	0.115926 (rank : 125)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	308	Target Neighborhood Hits	975	Shared Neighborhood Hits	135
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

STAB2_HUMAN
NC score	0.114452 (rank : 126)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	308	Target Neighborhood Hits	534	Shared Neighborhood Hits	119
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

WFDC2_HUMAN
NC score	0.113914 (rank : 127)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	308	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

KRA33_HUMAN
NC score	0.113335 (rank : 128)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	308	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

PCSK6_HUMAN
NC score	0.112551 (rank : 129)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	308	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

DLL3_HUMAN
NC score	0.112521 (rank : 130)	θ value	0.0961366 (rank : 102)
Query Neighborhood Hits	308	Target Neighborhood Hits	419	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

PCSK5_HUMAN
NC score	0.112174 (rank : 131)	θ value	0.0563607 (rank : 96)
Query Neighborhood Hits	308	Target Neighborhood Hits	291	Shared Neighborhood Hits	74
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

KR121_HUMAN
NC score	0.112015 (rank : 132)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	308	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

NOTC3_HUMAN
NC score	0.110847 (rank : 133)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	308	Target Neighborhood Hits	1062	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

STAB2_MOUSE
NC score	0.110724 (rank : 134)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	308	Target Neighborhood Hits	528	Shared Neighborhood Hits	119
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KRA32_HUMAN
NC score	0.110716 (rank : 135)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	308	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

NOTC1_MOUSE
NC score	0.108478 (rank : 136)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	308	Target Neighborhood Hits	916	Shared Neighborhood Hits	131
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
NC score	0.108387 (rank : 137)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	308	Target Neighborhood Hits	1113	Shared Neighborhood Hits	145
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
NC score	0.107475 (rank : 138)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	308	Target Neighborhood Hits	905	Shared Neighborhood Hits	135
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

SPR1A_MOUSE
NC score	0.107469 (rank : 139)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	308	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

NOTC4_MOUSE
NC score	0.107264 (rank : 140)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	308	Target Neighborhood Hits	872	Shared Neighborhood Hits	132
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN2_HUMAN
NC score	0.106822 (rank : 141)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	308	Target Neighborhood Hits	560	Shared Neighborhood Hits	121
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MUC2_HUMAN
NC score	0.106172 (rank : 142)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	308	Target Neighborhood Hits	906	Shared Neighborhood Hits	82
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

FBN2_MOUSE
NC score	0.105124 (rank : 143)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	308	Target Neighborhood Hits	549	Shared Neighborhood Hits	122
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.105007 (rank : 144)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	308	Target Neighborhood Hits	563	Shared Neighborhood Hits	123
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

HHIP_HUMAN
NC score	0.104704 (rank : 145)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	308	Target Neighborhood Hits	249	Shared Neighborhood Hits	81
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

JAG1_HUMAN
NC score	0.104525 (rank : 146)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	308	Target Neighborhood Hits	514	Shared Neighborhood Hits	113
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.104361 (rank : 147)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	308	Target Neighborhood Hits	518	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN1_HUMAN
NC score	0.103574 (rank : 148)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	308	Target Neighborhood Hits	557	Shared Neighborhood Hits	123
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

NOTC1_HUMAN
NC score	0.102785 (rank : 149)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	308	Target Neighborhood Hits	906	Shared Neighborhood Hits	129
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

JAG2_HUMAN
NC score	0.102008 (rank : 150)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	308	Target Neighborhood Hits	491	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

TECTA_MOUSE
NC score	0.100473 (rank : 151)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	308	Target Neighborhood Hits	244	Shared Neighborhood Hits	82
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

MEGF8_HUMAN
NC score	0.100037 (rank : 152)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	308	Target Neighborhood Hits	528	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
NC score	0.099979 (rank : 153)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	308	Target Neighborhood Hits	557	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NOTC2_MOUSE
NC score	0.099687 (rank : 154)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	308	Target Neighborhood Hits	1069	Shared Neighborhood Hits	133
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LAMB1_HUMAN
NC score	0.098767 (rank : 155)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	308	Target Neighborhood Hits	1018	Shared Neighborhood Hits	154
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TECTA_HUMAN
NC score	0.098692 (rank : 156)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	308	Target Neighborhood Hits	239	Shared Neighborhood Hits	79
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

DLK_HUMAN
NC score	0.098127 (rank : 157)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	308	Target Neighborhood Hits	401	Shared Neighborhood Hits	94
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

LRP1_HUMAN
NC score	0.097947 (rank : 158)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	308	Target Neighborhood Hits	617	Shared Neighborhood Hits	127
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

DLL1_MOUSE
NC score	0.097921 (rank : 159)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	308	Target Neighborhood Hits	456	Shared Neighborhood Hits	104
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

USH2A_MOUSE
NC score	0.097447 (rank : 160)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	308	Target Neighborhood Hits	626	Shared Neighborhood Hits	112
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

DLL1_HUMAN
NC score	0.096940 (rank : 161)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	308	Target Neighborhood Hits	455	Shared Neighborhood Hits	99
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

KRA31_HUMAN
NC score	0.096638 (rank : 162)	θ value	0.21417 (rank : 114)
Query Neighborhood Hits	308	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYR8	Gene names	KRTAP3-1, KAP3.1, KRTAP3.1
Domain Architecture
Description	Keratin-associated protein 3-1 (Keratin-associated protein 3.1) (High sulfur keratin-associated protein 3.1).

DLL4_MOUSE
NC score	0.095796 (rank : 163)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	308	Target Neighborhood Hits	440	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

RECK_HUMAN
NC score	0.095690 (rank : 164)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	308	Target Neighborhood Hits	189	Shared Neighborhood Hits	47
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

ITB2_MOUSE
NC score	0.095381 (rank : 165)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	308	Target Neighborhood Hits	326	Shared Neighborhood Hits	90
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LAMA2_HUMAN
NC score	0.095117 (rank : 166)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	308	Target Neighborhood Hits	1092	Shared Neighborhood Hits	153
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CREL1_HUMAN
NC score	0.094637 (rank : 167)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	308	Target Neighborhood Hits	441	Shared Neighborhood Hits	77
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FBN3_HUMAN
NC score	0.093976 (rank : 168)	θ value	0.62314 (rank : 135)
Query Neighborhood Hits	308	Target Neighborhood Hits	543	Shared Neighborhood Hits	118
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMA1_MOUSE
NC score	0.093927 (rank : 169)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	308	Target Neighborhood Hits	838	Shared Neighborhood Hits	147
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

DLL4_HUMAN
NC score	0.092805 (rank : 170)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	308	Target Neighborhood Hits	435	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LAMA2_MOUSE
NC score	0.092209 (rank : 171)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	308	Target Neighborhood Hits	1198	Shared Neighborhood Hits	152
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

DNER_HUMAN
NC score	0.092175 (rank : 172)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	308	Target Neighborhood Hits	460	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

NELL1_HUMAN
NC score	0.092131 (rank : 173)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	308	Target Neighborhood Hits	451	Shared Neighborhood Hits	105
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

CREL1_MOUSE
NC score	0.091350 (rank : 174)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	308	Target Neighborhood Hits	524	Shared Neighborhood Hits	80
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMB2_MOUSE
NC score	0.091175 (rank : 175)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	308	Target Neighborhood Hits	722	Shared Neighborhood Hits	134
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LTBP4_MOUSE
NC score	0.091142 (rank : 176)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	308	Target Neighborhood Hits	607	Shared Neighborhood Hits	98
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

JAG2_MOUSE
NC score	0.090500 (rank : 177)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	308	Target Neighborhood Hits	504	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

RECK_MOUSE
NC score	0.090060 (rank : 178)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	308	Target Neighborhood Hits	158	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

LAMC3_HUMAN
NC score	0.089637 (rank : 179)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	308	Target Neighborhood Hits	588	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTBP3_HUMAN
NC score	0.089303 (rank : 180)	θ value	0.47712 (rank : 128)
Query Neighborhood Hits	308	Target Neighborhood Hits	502	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LAMB2_HUMAN
NC score	0.088956 (rank : 181)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	308	Target Neighborhood Hits	692	Shared Neighborhood Hits	127
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

CRUM2_HUMAN
NC score	0.088646 (rank : 182)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	308	Target Neighborhood Hits	453	Shared Neighborhood Hits	96
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CX048_HUMAN
NC score	0.088620 (rank : 183)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	308	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

TRBM_MOUSE
NC score	0.088164 (rank : 184)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	308	Target Neighborhood Hits	361	Shared Neighborhood Hits	92
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_HUMAN
NC score	0.087464 (rank : 185)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	308	Target Neighborhood Hits	339	Shared Neighborhood Hits	79
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

MEGF8_MOUSE
NC score	0.087354 (rank : 186)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	308	Target Neighborhood Hits	520	Shared Neighborhood Hits	97
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NELL2_MOUSE
NC score	0.087050 (rank : 187)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	308	Target Neighborhood Hits	436	Shared Neighborhood Hits	91
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

KR241_HUMAN
NC score	0.086828 (rank : 188)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	308	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

SPR2J_MOUSE
NC score	0.086464 (rank : 189)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	308	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	O70561	Gene names	Sprr2j
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2J.

LAMC3_MOUSE
NC score	0.086288 (rank : 190)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	308	Target Neighborhood Hits	624	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB3_MOUSE
NC score	0.085784 (rank : 191)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	308	Target Neighborhood Hits	444	Shared Neighborhood Hits	103
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

DLK_MOUSE
NC score	0.085641 (rank : 192)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	308	Target Neighborhood Hits	374	Shared Neighborhood Hits	82
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LTBP2_HUMAN
NC score	0.085592 (rank : 193)	θ value	1.38821 (rank : 174)
Query Neighborhood Hits	308	Target Neighborhood Hits	552	Shared Neighborhood Hits	100
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TENR_MOUSE
NC score	0.085468 (rank : 194)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	308	Target Neighborhood Hits	531	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENR_HUMAN
NC score	0.085433 (rank : 195)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	308	Target Neighborhood Hits	526	Shared Neighborhood Hits	102
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

LAMA1_HUMAN
NC score	0.085149 (rank : 196)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	308	Target Neighborhood Hits	804	Shared Neighborhood Hits	139
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB1_MOUSE
NC score	0.085008 (rank : 197)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	308	Target Neighborhood Hits	919	Shared Neighborhood Hits	137
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRP2_HUMAN
NC score	0.084414 (rank : 198)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	308	Target Neighborhood Hits	573	Shared Neighborhood Hits	113
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SPR1A_HUMAN
NC score	0.084373 (rank : 199)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	308	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

DNER_MOUSE
NC score	0.084261 (rank : 200)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	308	Target Neighborhood Hits	413	Shared Neighborhood Hits	81
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

TRI42_MOUSE
NC score	0.083079 (rank : 201)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	308	Target Neighborhood Hits	316	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

SPR2K_MOUSE
NC score	0.082706 (rank : 202)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	308	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

MEGF9_MOUSE
NC score	0.082655 (rank : 203)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	308	Target Neighborhood Hits	896	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CP003_HUMAN
NC score	0.082590 (rank : 204)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	308	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

SPR1B_HUMAN
NC score	0.082571 (rank : 205)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	23
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

LAMC2_MOUSE
NC score	0.082493 (rank : 206)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	308	Target Neighborhood Hits	614	Shared Neighborhood Hits	122
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

CRUM1_HUMAN
NC score	0.081737 (rank : 207)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	308	Target Neighborhood Hits	457	Shared Neighborhood Hits	93
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NELL2_HUMAN
NC score	0.081267 (rank : 208)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	308	Target Neighborhood Hits	449	Shared Neighborhood Hits	91
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

DLL3_MOUSE
NC score	0.080848 (rank : 209)	θ value	0.163984 (rank : 110)
Query Neighborhood Hits	308	Target Neighborhood Hits	399	Shared Neighborhood Hits	72
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LRP1B_HUMAN
NC score	0.080397 (rank : 210)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	308	Target Neighborhood Hits	602	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

DYHC_MOUSE
NC score	0.079769 (rank : 211)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	308	Target Neighborhood Hits	729	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.079760 (rank : 212)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	308	Target Neighborhood Hits	733	Shared Neighborhood Hits	64
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

EGFL9_MOUSE
NC score	0.079752 (rank : 213)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	308	Target Neighborhood Hits	379	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LCE3A_HUMAN
NC score	0.079577 (rank : 214)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	308	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

ATRN_MOUSE
NC score	0.079411 (rank : 215)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	308	Target Neighborhood Hits	519	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LRP1B_MOUSE
NC score	0.079250 (rank : 216)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	308	Target Neighborhood Hits	606	Shared Neighborhood Hits	119
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTBP3_MOUSE
NC score	0.079201 (rank : 217)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	308	Target Neighborhood Hits	475	Shared Neighborhood Hits	94
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LAMC1_HUMAN
NC score	0.079156 (rank : 218)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	308	Target Neighborhood Hits	922	Shared Neighborhood Hits	150
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

EGFL9_HUMAN
NC score	0.079014 (rank : 219)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	308	Target Neighborhood Hits	365	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

ITB5_MOUSE
NC score	0.078903 (rank : 220)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	308	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

LTBP2_MOUSE
NC score	0.078832 (rank : 221)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	308	Target Neighborhood Hits	617	Shared Neighborhood Hits	99
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ITB3_HUMAN
NC score	0.078258 (rank : 222)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	308	Target Neighborhood Hits	325	Shared Neighborhood Hits	86
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ADA17_MOUSE
NC score	0.077932 (rank : 223)	θ value	0.813845 (rank : 142)
Query Neighborhood Hits	308	Target Neighborhood Hits	201	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

LAMA3_MOUSE
NC score	0.077889 (rank : 224)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	308	Target Neighborhood Hits	859	Shared Neighborhood Hits	150
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LCE4A_HUMAN
NC score	0.077463 (rank : 225)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	308	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

CRUM1_MOUSE
NC score	0.077224 (rank : 226)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	308	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LAMC1_MOUSE
NC score	0.076831 (rank : 227)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	308	Target Neighborhood Hits	856	Shared Neighborhood Hits	137
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ERBB3_HUMAN
NC score	0.076456 (rank : 228)	θ value	0.000270298 (rank : 59)
Query Neighborhood Hits	308	Target Neighborhood Hits	918	Shared Neighborhood Hits	63
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ITB3_MOUSE
NC score	0.075688 (rank : 229)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	308	Target Neighborhood Hits	319	Shared Neighborhood Hits	81
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ADA17_HUMAN
NC score	0.075315 (rank : 230)	θ value	1.06291 (rank : 155)
Query Neighborhood Hits	308	Target Neighborhood Hits	223	Shared Neighborhood Hits	56
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

LAMB3_HUMAN
NC score	0.074657 (rank : 231)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	308	Target Neighborhood Hits	461	Shared Neighborhood Hits	104
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC2_HUMAN
NC score	0.073392 (rank : 232)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	308	Target Neighborhood Hits	715	Shared Neighborhood Hits	117
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MT4_MOUSE
NC score	0.073238 (rank : 233)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

INSR_HUMAN
NC score	0.071317 (rank : 234)	θ value	1.43324e-05 (rank : 47)
Query Neighborhood Hits	308	Target Neighborhood Hits	963	Shared Neighborhood Hits	70
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
NC score	0.071204 (rank : 235)	θ value	8.40245e-06 (rank : 43)
Query Neighborhood Hits	308	Target Neighborhood Hits	968	Shared Neighborhood Hits	72
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FSTL3_MOUSE
NC score	0.071180 (rank : 236)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	308	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ITB2_HUMAN
NC score	0.070956 (rank : 237)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	308	Target Neighborhood Hits	282	Shared Neighborhood Hits	73
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

RSPO4_MOUSE
NC score	0.070879 (rank : 238)	θ value	3.0926 (rank : 223)
Query Neighborhood Hits	308	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ERBB3_MOUSE
NC score	0.070806 (rank : 239)	θ value	0.00509761 (rank : 75)
Query Neighborhood Hits	308	Target Neighborhood Hits	898	Shared Neighborhood Hits	54
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ATRN_HUMAN
NC score	0.070367 (rank : 240)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	308	Target Neighborhood Hits	525	Shared Neighborhood Hits	80
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

IGF1R_HUMAN
NC score	0.070151 (rank : 241)	θ value	0.0113563 (rank : 79)
Query Neighborhood Hits	308	Target Neighborhood Hits	977	Shared Neighborhood Hits	86
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LTB1L_MOUSE
NC score	0.068533 (rank : 242)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	308	Target Neighborhood Hits	514	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.068304 (rank : 243)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	308	Target Neighborhood Hits	553	Shared Neighborhood Hits	93
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FIP1_MOUSE
NC score	0.068302 (rank : 244)	θ value	1.38821 (rank : 170)
Query Neighborhood Hits	308	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

USH2A_HUMAN
NC score	0.067902 (rank : 245)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	308	Target Neighborhood Hits	600	Shared Neighborhood Hits	84
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ITB6_MOUSE
NC score	0.067277 (rank : 246)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	308	Target Neighborhood Hits	341	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB8_HUMAN
NC score	0.066986 (rank : 247)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	308	Target Neighborhood Hits	280	Shared Neighborhood Hits	72
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

FIP1_HUMAN
NC score	0.066800 (rank : 248)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	308	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

SIVA_MOUSE
NC score	0.066263 (rank : 249)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	308	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	O54926, Q3U6J2, Q921I8, Q9CWL1, Q9R1Q0, Q9R1Q1	Gene names	Siva
Domain Architecture
Description	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

FBLN2_HUMAN
NC score	0.066189 (rank : 250)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	308	Target Neighborhood Hits	392	Shared Neighborhood Hits	73
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ITB5_HUMAN
NC score	0.066017 (rank : 251)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	308	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

FST_MOUSE
NC score	0.065987 (rank : 252)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	308	Target Neighborhood Hits	146	Shared Neighborhood Hits	44
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADAM8_HUMAN
NC score	0.065572 (rank : 253)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	308	Target Neighborhood Hits	327	Shared Neighborhood Hits	90
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CRDL2_MOUSE
NC score	0.065545 (rank : 254)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	308	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

SPR1B_MOUSE
NC score	0.065121 (rank : 255)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	308	Target Neighborhood Hits	395	Shared Neighborhood Hits	30
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TENN_MOUSE
NC score	0.065082 (rank : 256)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	308	Target Neighborhood Hits	484	Shared Neighborhood Hits	94
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

IGF1R_MOUSE
NC score	0.064690 (rank : 257)	θ value	0.0736092 (rank : 97)
Query Neighborhood Hits	308	Target Neighborhood Hits	973	Shared Neighborhood Hits	79
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ITB7_HUMAN
NC score	0.064602 (rank : 258)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	308	Target Neighborhood Hits	290	Shared Neighborhood Hits	71
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LTB1S_MOUSE
NC score	0.064381 (rank : 259)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	308	Target Neighborhood Hits	479	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.064257 (rank : 260)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	308	Target Neighborhood Hits	502	Shared Neighborhood Hits	79
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

C1QR1_HUMAN
NC score	0.064205 (rank : 261)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	308	Target Neighborhood Hits	493	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

SCUB3_MOUSE
NC score	0.064010 (rank : 262)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	308	Target Neighborhood Hits	442	Shared Neighborhood Hits	81
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LDLR_MOUSE
NC score	0.063937 (rank : 263)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	308	Target Neighborhood Hits	382	Shared Neighborhood Hits	84
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

EGFL7_HUMAN
NC score	0.063735 (rank : 264)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	308	Target Neighborhood Hits	325	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFR_MOUSE
NC score	0.063571 (rank : 265)	θ value	9.29e-05 (rank : 55)
Query Neighborhood Hits	308	Target Neighborhood Hits	927	Shared Neighborhood Hits	42
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EGFR_HUMAN
NC score	0.063388 (rank : 266)	θ value	0.00509761 (rank : 73)
Query Neighborhood Hits	308	Target Neighborhood Hits	939	Shared Neighborhood Hits	63
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

CCD42_HUMAN
NC score	0.063170 (rank : 267)	θ value	0.0431538 (rank : 90)
Query Neighborhood Hits	308	Target Neighborhood Hits	406	Shared Neighborhood Hits	40
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

WFDC5_HUMAN
NC score	0.063161 (rank : 268)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	308	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

ITB6_HUMAN
NC score	0.063152 (rank : 269)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	308	Target Neighborhood Hits	318	Shared Neighborhood Hits	81
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

FBLN1_MOUSE
NC score	0.062630 (rank : 270)	θ value	0.47712 (rank : 127)
Query Neighborhood Hits	308	Target Neighborhood Hits	329	Shared Neighborhood Hits	65
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

ADAM8_MOUSE
NC score	0.062367 (rank : 271)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	308	Target Neighborhood Hits	326	Shared Neighborhood Hits	86
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

MATN2_MOUSE
NC score	0.062050 (rank : 272)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	308	Target Neighborhood Hits	356	Shared Neighborhood Hits	71
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

TNR4_MOUSE
NC score	0.061925 (rank : 273)	θ value	0.0961366 (rank : 104)
Query Neighborhood Hits	308	Target Neighborhood Hits	137	Shared Neighborhood Hits	20
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

SLIT3_MOUSE
NC score	0.061766 (rank : 274)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	308	Target Neighborhood Hits	700	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ERBB2_MOUSE
NC score	0.061682 (rank : 275)	θ value	0.00509761 (rank : 74)
Query Neighborhood Hits	308	Target Neighborhood Hits	918	Shared Neighborhood Hits	48
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

LAMA3_HUMAN
NC score	0.061619 (rank : 276)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	308	Target Neighborhood Hits	760	Shared Neighborhood Hits	112
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

ERBB4_HUMAN
NC score	0.061400 (rank : 277)	θ value	0.0431538 (rank : 93)
Query Neighborhood Hits	308	Target Neighborhood Hits	910	Shared Neighborhood Hits	53
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ADA15_HUMAN
NC score	0.061379 (rank : 278)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	308	Target Neighborhood Hits	288	Shared Neighborhood Hits	81
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

HHIP_MOUSE
NC score	0.061336 (rank : 279)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	308	Target Neighborhood Hits	219	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB7_MOUSE
NC score	0.060582 (rank : 280)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	308	Target Neighborhood Hits	277	Shared Neighborhood Hits	66
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

KR151_HUMAN
NC score	0.060389 (rank : 281)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	308	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	Q3LI76	Gene names	KRTAP15-1, KAP15.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 15-1.

ERBB2_HUMAN
NC score	0.059862 (rank : 282)	θ value	0.125558 (rank : 105)
Query Neighborhood Hits	308	Target Neighborhood Hits	1073	Shared Neighborhood Hits	51
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

SCUB3_HUMAN
NC score	0.059844 (rank : 283)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	308	Target Neighborhood Hits	428	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EGFL7_MOUSE
NC score	0.059472 (rank : 284)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	308	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

VLDLR_HUMAN
NC score	0.058949 (rank : 285)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	308	Target Neighborhood Hits	383	Shared Neighborhood Hits	77
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ADA18_MOUSE
NC score	0.058924 (rank : 286)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	308	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA10_MOUSE
NC score	0.058795 (rank : 287)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	308	Target Neighborhood Hits	194	Shared Neighborhood Hits	59
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

INSRR_MOUSE
NC score	0.058720 (rank : 288)	θ value	0.125558 (rank : 107)
Query Neighborhood Hits	308	Target Neighborhood Hits	961	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LDLR_HUMAN
NC score	0.058558 (rank : 289)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	308	Target Neighborhood Hits	375	Shared Neighborhood Hits	85
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CRDL2_HUMAN
NC score	0.058392 (rank : 290)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	308	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

MT3_HUMAN
NC score	0.058354 (rank : 291)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	308	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

FBLN1_HUMAN
NC score	0.058246 (rank : 292)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	308	Target Neighborhood Hits	324	Shared Neighborhood Hits	66
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FSTL3_HUMAN
NC score	0.058089 (rank : 293)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	308	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

CHRD_HUMAN
NC score	0.058078 (rank : 294)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

MATN2_HUMAN
NC score	0.058017 (rank : 295)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	308	Target Neighborhood Hits	365	Shared Neighborhood Hits	63
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

RSPO4_HUMAN
NC score	0.057947 (rank : 296)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	308	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

FBLN2_MOUSE
NC score	0.057852 (rank : 297)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	308	Target Neighborhood Hits	505	Shared Neighborhood Hits	78
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN5_HUMAN
NC score	0.057733 (rank : 298)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	308	Target Neighborhood Hits	329	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

ITB1_HUMAN
NC score	0.057456 (rank : 299)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	308	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

RSPO3_HUMAN
NC score	0.057231 (rank : 300)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	308	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

TSP2_HUMAN
NC score	0.056829 (rank : 301)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	308	Target Neighborhood Hits	359	Shared Neighborhood Hits	86
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TIE1_HUMAN
NC score	0.056753 (rank : 302)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	308	Target Neighborhood Hits	1241	Shared Neighborhood Hits	97
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CUBN_HUMAN
NC score	0.056436 (rank : 303)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	308	Target Neighborhood Hits	482	Shared Neighborhood Hits	81
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

SLIT1_HUMAN
NC score	0.056412 (rank : 304)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	308	Target Neighborhood Hits	700	Shared Neighborhood Hits	90
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

RSPO3_MOUSE
NC score	0.056130 (rank : 305)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	308	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

CING_HUMAN
NC score	0.056064 (rank : 306)	θ value	0.0961366 (rank : 101)
Query Neighborhood Hits	308	Target Neighborhood Hits	1275	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DYH5_MOUSE
NC score	0.055804 (rank : 307)	θ value	0.163984 (rank : 111)
Query Neighborhood Hits	308	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

BPAEA_HUMAN
NC score	0.055683 (rank : 308)	θ value	0.0431538 (rank : 89)
Query Neighborhood Hits	308	Target Neighborhood Hits	1369	Shared Neighborhood Hits	67
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DYH5_HUMAN
NC score	0.055627 (rank : 309)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	308	Target Neighborhood Hits	323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

SORL_MOUSE
NC score	0.055525 (rank : 310)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	308	Target Neighborhood Hits	439	Shared Neighborhood Hits	72
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TNR25_HUMAN
NC score	0.055473 (rank : 311)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	308	Target Neighborhood Hits	172	Shared Neighborhood Hits	33
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

EZH1_MOUSE
NC score	0.054929 (rank : 312)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	308	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

CUBN_MOUSE
NC score	0.054844 (rank : 313)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	308	Target Neighborhood Hits	477	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

ADAM7_HUMAN
NC score	0.054413 (rank : 314)	θ value	0.0193708 (rank : 84)
Query Neighborhood Hits	308	Target Neighborhood Hits	221	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADA15_MOUSE
NC score	0.054407 (rank : 315)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	308	Target Neighborhood Hits	324	Shared Neighborhood Hits	79
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

TNR8_MOUSE
NC score	0.054404 (rank : 316)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	308	Target Neighborhood Hits	208	Shared Neighborhood Hits	39
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

ODFP_HUMAN
NC score	0.054321 (rank : 317)	θ value	1.38821 (rank : 175)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

C1QR1_MOUSE
NC score	0.053975 (rank : 318)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	308	Target Neighborhood Hits	342	Shared Neighborhood Hits	71
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CHRD_MOUSE
NC score	0.053859 (rank : 319)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	308	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

TIE1_MOUSE
NC score	0.053542 (rank : 320)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	308	Target Neighborhood Hits	1266	Shared Neighborhood Hits	98
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SMC3_HUMAN
NC score	0.052925 (rank : 321)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	308	Target Neighborhood Hits	1186	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
NC score	0.052900 (rank : 322)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	308	Target Neighborhood Hits	1187	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

FBLN5_MOUSE
NC score	0.052811 (rank : 323)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	308	Target Neighborhood Hits	317	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

MCSP_HUMAN
NC score	0.052680 (rank : 324)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	308	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

TENN_HUMAN
NC score	0.052600 (rank : 325)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	308	Target Neighborhood Hits	453	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

K1H2_HUMAN
NC score	0.052596 (rank : 326)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	308	Target Neighborhood Hits	492	Shared Neighborhood Hits	84
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

ADA10_HUMAN
NC score	0.052485 (rank : 327)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	308	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

INSRR_HUMAN
NC score	0.052446 (rank : 328)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	308	Target Neighborhood Hits	950	Shared Neighborhood Hits	68
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

TSP2_MOUSE
NC score	0.052034 (rank : 329)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	308	Target Neighborhood Hits	352	Shared Neighborhood Hits	80
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

FBLN4_HUMAN
NC score	0.051374 (rank : 330)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	308	Target Neighborhood Hits	278	Shared Neighborhood Hits	55
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

LAMA4_HUMAN
NC score	0.051250 (rank : 331)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	308	Target Neighborhood Hits	708	Shared Neighborhood Hits	91
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TSP1_HUMAN
NC score	0.051176 (rank : 332)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	308	Target Neighborhood Hits	389	Shared Neighborhood Hits	76
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

FBLN4_MOUSE
NC score	0.051004 (rank : 333)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	308	Target Neighborhood Hits	270	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

SLIT1_MOUSE
NC score	0.050925 (rank : 334)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	308	Target Neighborhood Hits	715	Shared Neighborhood Hits	102
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

TRIPB_HUMAN
NC score	0.050463 (rank : 335)	θ value	0.47712 (rank : 129)
Query Neighborhood Hits	308	Target Neighborhood Hits	1587	Shared Neighborhood Hits	71
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

SMC1A_HUMAN
NC score	0.049961 (rank : 336)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	308	Target Neighborhood Hits	1346	Shared Neighborhood Hits	69
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

EZH1_HUMAN
NC score	0.049953 (rank : 337)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	308	Target Neighborhood Hits	121	Shared Neighborhood Hits	39
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

BPA1_MOUSE
NC score	0.049567 (rank : 338)	θ value	0.0563607 (rank : 94)
Query Neighborhood Hits	308	Target Neighborhood Hits	1477	Shared Neighborhood Hits	73
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD46_HUMAN
NC score	0.049050 (rank : 339)	θ value	0.0961366 (rank : 100)
Query Neighborhood Hits	308	Target Neighborhood Hits	1430	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SYNE1_HUMAN
NC score	0.048777 (rank : 340)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	308	Target Neighborhood Hits	1484	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SMC1A_MOUSE
NC score	0.048312 (rank : 341)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	308	Target Neighborhood Hits	1384	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

GOGB1_HUMAN
NC score	0.048181 (rank : 342)	θ value	0.813845 (rank : 147)
Query Neighborhood Hits	308	Target Neighborhood Hits	2297	Shared Neighborhood Hits	77
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

UTRO_HUMAN
NC score	0.047633 (rank : 343)	θ value	0.279714 (rank : 118)
Query Neighborhood Hits	308	Target Neighborhood Hits	960	Shared Neighborhood Hits	65
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

CCD46_MOUSE
NC score	0.047551 (rank : 344)	θ value	0.163984 (rank : 109)
Query Neighborhood Hits	308	Target Neighborhood Hits	1405	Shared Neighborhood Hits	71
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

NELFE_HUMAN
NC score	0.047443 (rank : 345)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	308	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

TIE2_MOUSE
NC score	0.047305 (rank : 346)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	308	Target Neighborhood Hits	1204	Shared Neighborhood Hits	79
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CENPF_HUMAN
NC score	0.046571 (rank : 347)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	308	Target Neighborhood Hits	1932	Shared Neighborhood Hits	80
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

EGF_HUMAN
NC score	0.046290 (rank : 348)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	308	Target Neighborhood Hits	343	Shared Neighborhood Hits	61
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

RAD50_HUMAN
NC score	0.046224 (rank : 349)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	308	Target Neighborhood Hits	1317	Shared Neighborhood Hits	68
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CCD41_HUMAN
NC score	0.046205 (rank : 350)	θ value	0.21417 (rank : 113)
Query Neighborhood Hits	308	Target Neighborhood Hits	1139	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

EZH2_MOUSE
NC score	0.046198 (rank : 351)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	308	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_HUMAN
NC score	0.045981 (rank : 352)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	308	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

CD248_MOUSE
NC score	0.045780 (rank : 353)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	308	Target Neighborhood Hits	578	Shared Neighborhood Hits	53
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CROCC_HUMAN
NC score	0.045593 (rank : 354)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	308	Target Neighborhood Hits	1409	Shared Neighborhood Hits	73
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA4_MOUSE
NC score	0.045565 (rank : 355)	θ value	0.125558 (rank : 106)
Query Neighborhood Hits	308	Target Neighborhood Hits	1939	Shared Neighborhood Hits	77
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CNOT3_MOUSE
NC score	0.045501 (rank : 356)	θ value	1.06291 (rank : 157)
Query Neighborhood Hits	308	Target Neighborhood Hits	504	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

LIPA2_HUMAN
NC score	0.045353 (rank : 357)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	308	Target Neighborhood Hits	1044	Shared Neighborhood Hits	64
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

GCC2_HUMAN
NC score	0.045339 (rank : 358)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	308	Target Neighborhood Hits	1558	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.045037 (rank : 359)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	308	Target Neighborhood Hits	1559	Shared Neighborhood Hits	73
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CING_MOUSE
NC score	0.044745 (rank : 360)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	308	Target Neighborhood Hits	1432	Shared Neighborhood Hits	70
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

AD26A_MOUSE
NC score	0.044659 (rank : 361)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	308	Target Neighborhood Hits	165	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

TIE2_HUMAN
NC score	0.043962 (rank : 362)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	308	Target Neighborhood Hits	1192	Shared Neighborhood Hits	72
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

HMCN1_HUMAN
NC score	0.043896 (rank : 363)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	308	Target Neighborhood Hits	983	Shared Neighborhood Hits	92
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ADA24_MOUSE
NC score	0.043623 (rank : 364)	θ value	1.81305 (rank : 184)
Query Neighborhood Hits	308	Target Neighborhood Hits	230	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

PROS_MOUSE
NC score	0.043202 (rank : 365)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	308	Target Neighborhood Hits	330	Shared Neighborhood Hits	58
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GCC2_MOUSE
NC score	0.043169 (rank : 366)	θ value	0.813845 (rank : 146)
Query Neighborhood Hits	308	Target Neighborhood Hits	1619	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CP135_HUMAN
NC score	0.042918 (rank : 367)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	308	Target Neighborhood Hits	1290	Shared Neighborhood Hits	71
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CNOT3_HUMAN
NC score	0.042838 (rank : 368)	θ value	1.06291 (rank : 156)
Query Neighborhood Hits	308	Target Neighborhood Hits	425	Shared Neighborhood Hits	35
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

TR13B_HUMAN
NC score	0.042773 (rank : 369)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	308	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

PIBF1_HUMAN
NC score	0.042164 (rank : 370)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	308	Target Neighborhood Hits	1041	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PUS7_HUMAN
NC score	0.041965 (rank : 371)	θ value	0.62314 (rank : 139)
Query Neighborhood Hits	308	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PZ0, Q75MG4, Q9NX19	Gene names	PUS7, KIAA1897
Domain Architecture
Description	Pseudouridylate synthase 7 homolog (EC 5.4.99.-).

CELR3_MOUSE
NC score	0.041597 (rank : 372)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	308	Target Neighborhood Hits	687	Shared Neighborhood Hits	94
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

FLIP1_MOUSE
NC score	0.041225 (rank : 373)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	308	Target Neighborhood Hits	1176	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA2_HUMAN
NC score	0.040684 (rank : 374)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	308	Target Neighborhood Hits	856	Shared Neighborhood Hits	60
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

VPS72_HUMAN
NC score	0.040655 (rank : 375)	θ value	0.365318 (rank : 125)
Query Neighborhood Hits	308	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

NUMA1_HUMAN
NC score	0.040653 (rank : 376)	θ value	3.0926 (rank : 221)
Query Neighborhood Hits	308	Target Neighborhood Hits	1523	Shared Neighborhood Hits	65
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

BICD1_HUMAN
NC score	0.040402 (rank : 377)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	308	Target Neighborhood Hits	844	Shared Neighborhood Hits	66
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

C8AP2_MOUSE
NC score	0.040276 (rank : 378)	θ value	0.813845 (rank : 144)
Query Neighborhood Hits	308	Target Neighborhood Hits	405	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

TRAF5_MOUSE
NC score	0.040090 (rank : 379)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	308	Target Neighborhood Hits	355	Shared Neighborhood Hits	43
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

CS029_MOUSE
NC score	0.039641 (rank : 380)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	308	Target Neighborhood Hits	201	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CCD45_HUMAN
NC score	0.039529 (rank : 381)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	308	Target Neighborhood Hits	525	Shared Neighborhood Hits	51
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

P5CS_MOUSE
NC score	0.039314 (rank : 382)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	308	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z110, Q9R1P6	Gene names	Aldh18a1, P5cs, Pycs
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

FBX18_HUMAN
NC score	0.038452 (rank : 383)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	308	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

NIN_MOUSE
NC score	0.038128 (rank : 384)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	308	Target Neighborhood Hits	1376	Shared Neighborhood Hits	64
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

VPS72_MOUSE
NC score	0.037047 (rank : 385)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	308	Target Neighborhood Hits	286	Shared Neighborhood Hits	8
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

KMHN1_MOUSE
NC score	0.037018 (rank : 386)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	308	Target Neighborhood Hits	949	Shared Neighborhood Hits	59
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LIPA3_HUMAN
NC score	0.036699 (rank : 387)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	308	Target Neighborhood Hits	828	Shared Neighborhood Hits	61
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

BICD1_MOUSE
NC score	0.036235 (rank : 388)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	308	Target Neighborhood Hits	837	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCD45_MOUSE
NC score	0.035928 (rank : 389)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	308	Target Neighborhood Hits	663	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

UACA_MOUSE
NC score	0.035610 (rank : 390)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	308	Target Neighborhood Hits	1620	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

EST1A_MOUSE
NC score	0.035452 (rank : 391)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	308	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

TRAF4_HUMAN
NC score	0.035219 (rank : 392)	θ value	0.163984 (rank : 112)
Query Neighborhood Hits	308	Target Neighborhood Hits	373	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

EST1A_HUMAN
NC score	0.035164 (rank : 393)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	308	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

KLC1_HUMAN
NC score	0.034729 (rank : 394)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	308	Target Neighborhood Hits	471	Shared Neighborhood Hits	49
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

TXLNB_MOUSE
NC score	0.034434 (rank : 395)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	308	Target Neighborhood Hits	640	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

LRC45_MOUSE
NC score	0.034229 (rank : 396)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	308	Target Neighborhood Hits	959	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

EP15_MOUSE
NC score	0.034222 (rank : 397)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	308	Target Neighborhood Hits	820	Shared Neighborhood Hits	59
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

LIPA2_MOUSE
NC score	0.034021 (rank : 398)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	308	Target Neighborhood Hits	1282	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CENPE_HUMAN
NC score	0.033843 (rank : 399)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	308	Target Neighborhood Hits	2060	Shared Neighborhood Hits	74
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

UACA_HUMAN
NC score	0.033816 (rank : 400)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	308	Target Neighborhood Hits	1622	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

TXLNG_HUMAN
NC score	0.033737 (rank : 401)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	308	Target Neighborhood Hits	568	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

UT14B_MOUSE
NC score	0.033521 (rank : 402)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	308	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

TRAF4_MOUSE
NC score	0.032674 (rank : 403)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	308	Target Neighborhood Hits	338	Shared Neighborhood Hits	6
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

P5CS_HUMAN
NC score	0.032590 (rank : 404)	θ value	3.0926 (rank : 222)
Query Neighborhood Hits	308	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P54886, O95952, Q9UM72	Gene names	ALDH18A1, P5CS, PYCS
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

TNR3_MOUSE
NC score	0.032157 (rank : 405)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	308	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

KLC1_MOUSE
NC score	0.032018 (rank : 406)	θ value	1.38821 (rank : 173)
Query Neighborhood Hits	308	Target Neighborhood Hits	357	Shared Neighborhood Hits	45
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

CT2NL_MOUSE
NC score	0.031815 (rank : 407)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	308	Target Neighborhood Hits	902	Shared Neighborhood Hits	54
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ADA12_MOUSE
NC score	0.031758 (rank : 408)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	308	Target Neighborhood Hits	474	Shared Neighborhood Hits	53
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_MOUSE
NC score	0.031646 (rank : 409)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	308	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

RAI14_HUMAN
NC score	0.031512 (rank : 410)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	308	Target Neighborhood Hits	1367	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

EP15_HUMAN
NC score	0.030674 (rank : 411)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	308	Target Neighborhood Hits	1021	Shared Neighborhood Hits	61
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MYH3_HUMAN
NC score	0.030525 (rank : 412)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	308	Target Neighborhood Hits	1660	Shared Neighborhood Hits	71
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

LYPD1_HUMAN
NC score	0.030284 (rank : 413)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	308	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2G4, Q96AC2	Gene names	LYPD1, LYPDC1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

SPTB1_HUMAN
NC score	0.029270 (rank : 414)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	308	Target Neighborhood Hits	541	Shared Neighborhood Hits	52
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTA1_MOUSE
NC score	0.028945 (rank : 415)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	308	Target Neighborhood Hits	675	Shared Neighborhood Hits	50
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ILF2_HUMAN
NC score	0.028432 (rank : 416)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	308	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
NC score	0.028432 (rank : 417)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	308	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

NSD1_MOUSE
NC score	0.027162 (rank : 418)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	308	Target Neighborhood Hits	472	Shared Neighborhood Hits	25
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CUTL1_MOUSE
NC score	0.026842 (rank : 419)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	308	Target Neighborhood Hits	1620	Shared Neighborhood Hits	71
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RPTN_MOUSE
NC score	0.026568 (rank : 420)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	308	Target Neighborhood Hits	650	Shared Neighborhood Hits	19
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

NSD1_HUMAN
NC score	0.026252 (rank : 421)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	308	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

BRAP_HUMAN
NC score	0.025281 (rank : 422)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	308	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

FILA_HUMAN
NC score	0.024506 (rank : 423)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	308	Target Neighborhood Hits	685	Shared Neighborhood Hits	17
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NHLC1_HUMAN
NC score	0.023591 (rank : 424)	θ value	3.0926 (rank : 220)
Query Neighborhood Hits	308	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

LRP6_HUMAN
NC score	0.023548 (rank : 425)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	308	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

WISP1_HUMAN
NC score	0.023398 (rank : 426)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	308	Target Neighborhood Hits	121	Shared Neighborhood Hits	20
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

TRI26_HUMAN
NC score	0.022488 (rank : 427)	θ value	0.279714 (rank : 117)
Query Neighborhood Hits	308	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

ROCK1_MOUSE
NC score	0.020588 (rank : 428)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	308	Target Neighborhood Hits	2126	Shared Neighborhood Hits	81
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

PEX6_MOUSE
NC score	0.020474 (rank : 429)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	308	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
NC score	0.019892 (rank : 430)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	308	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

CK5P3_MOUSE
NC score	0.019227 (rank : 431)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	308	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LM2, Q3UE41	Gene names	Cdk5rap3
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3.

TRI31_HUMAN
NC score	0.019101 (rank : 432)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	308	Target Neighborhood Hits	299	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI26_MOUSE
NC score	0.017929 (rank : 433)	θ value	0.365318 (rank : 124)
Query Neighborhood Hits	308	Target Neighborhood Hits	339	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

ADEC1_HUMAN
NC score	0.017373 (rank : 434)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	308	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

MA1A1_MOUSE
NC score	0.016902 (rank : 435)	θ value	0.62314 (rank : 138)
Query Neighborhood Hits	308	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P45700	Gene names	Man1a1, Man1a
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

SEBP2_HUMAN
NC score	0.015493 (rank : 436)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	308	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

TCGAP_MOUSE
NC score	0.015493 (rank : 437)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	308	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SNIP1_HUMAN
NC score	0.015331 (rank : 438)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	308	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

RUVB1_HUMAN
NC score	0.015050 (rank : 439)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	308	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.015048 (rank : 440)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	308	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

ZGPAT_MOUSE
NC score	0.014905 (rank : 441)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	308	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

DGKE_MOUSE
NC score	0.014489 (rank : 442)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	308	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

PKCB1_HUMAN
NC score	0.013395 (rank : 443)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	308	Target Neighborhood Hits	488	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RNUXA_HUMAN
NC score	0.013295 (rank : 444)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	308	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H814, Q9H8W1	Gene names	RNUXA, PHAX
Domain Architecture	No domain graphic available
Description	RNA U small nuclear RNA export adapter protein (Phosphorylated adapter RNA export protein).

TCGAP_HUMAN
NC score	0.013175 (rank : 445)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	308	Target Neighborhood Hits	872	Shared Neighborhood Hits	15
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

EHMT2_HUMAN
NC score	0.012010 (rank : 446)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	308	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FANCG_MOUSE
NC score	0.011986 (rank : 447)	θ value	6.88961 (rank : 278)
Query Neighborhood Hits	308	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQR6	Gene names	Fancg
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein homolog (Protein FACG).

DGUOK_MOUSE
NC score	0.011208 (rank : 448)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	308	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QX60, Q9R0Y2, Q9WUT9	Gene names	Dguok, Dgk
Domain Architecture
Description	Deoxyguanosine kinase, mitochondrial precursor (EC 2.7.1.113) (dGK).

MKRN3_HUMAN
NC score	0.010928 (rank : 449)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	308	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

TSH1_HUMAN
NC score	0.010092 (rank : 450)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	308	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

EHMT2_MOUSE
NC score	0.010049 (rank : 451)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	308	Target Neighborhood Hits	750	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

AMGO3_MOUSE
NC score	0.009526 (rank : 452)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	308	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

MCF2_HUMAN
NC score	0.009429 (rank : 453)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	308	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

STAT6_MOUSE
NC score	0.008955 (rank : 454)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	308	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

E41L3_HUMAN
NC score	0.007931 (rank : 455)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	308	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

PARP2_HUMAN
NC score	0.007930 (rank : 456)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	308	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

GALT8_HUMAN
NC score	0.007769 (rank : 457)	θ value	1.38821 (rank : 171)
Query Neighborhood Hits	308	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY28	Gene names	GALNT8
Domain Architecture	No domain graphic available
Description	Probable polypeptide N-acetylgalactosaminyltransferase 8 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 8) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 8) (Polypeptide GalNAc transferase 8) (GalNAc-T8) (pp-GaNTase 8).

FCER2_HUMAN
NC score	0.007089 (rank : 458)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	308	Target Neighborhood Hits	213	Shared Neighborhood Hits	18
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

UN13B_HUMAN
NC score	0.006945 (rank : 459)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	308	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

GPC5B_MOUSE
NC score	0.005658 (rank : 460)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	308	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

FHL2_MOUSE
NC score	0.003738 (rank : 461)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	308	Target Neighborhood Hits	539	Shared Neighborhood Hits	9
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

GPV_MOUSE
NC score	0.002556 (rank : 462)	θ value	1.38821 (rank : 172)
Query Neighborhood Hits	308	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

ZN592_MOUSE
NC score	-0.000544 (rank : 463)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	308	Target Neighborhood Hits	768	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ZN592_HUMAN
NC score	-0.000908 (rank : 464)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	308	Target Neighborhood Hits	762	Shared Neighborhood Hits	5
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.