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Network neighborhood for query Sequence : SMBP2_HUMAN

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SMBP2_HUMAN
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMBP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
θ value	0 (rank : 2)	NC score	0.979198 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

RENT1_HUMAN
θ value	2.18568e-46 (rank : 3)	NC score	0.816993 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	2.18568e-46 (rank : 4)	NC score	0.816832 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

SETX_HUMAN
θ value	1.9192e-34 (rank : 5)	NC score	0.711939 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

M10L1_HUMAN
θ value	2.05525e-28 (rank : 6)	NC score	0.722401 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
θ value	8.63488e-27 (rank : 7)	NC score	0.708699 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

MOV10_MOUSE
θ value	1.62847e-25 (rank : 8)	NC score	0.723248 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_HUMAN
θ value	3.62785e-25 (rank : 9)	NC score	0.721183 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

PR285_HUMAN
θ value	3.62785e-25 (rank : 10)	NC score	0.708850 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

ZNFX1_MOUSE
θ value	1.29331e-14 (rank : 11)	NC score	0.475915 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	407	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

HELZ_HUMAN
θ value	2.43908e-13 (rank : 12)	NC score	0.628751 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

ZNFX1_HUMAN
θ value	5.43371e-13 (rank : 13)	NC score	0.471664 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_HUMAN
θ value	2.13673e-09 (rank : 14)	NC score	0.478201 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	2.13673e-09 (rank : 15)	NC score	0.481119 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

ZFAN6_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.081719 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

DHX57_MOUSE
θ value	0.0148317 (rank : 17)	NC score	0.074412 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

BAT2_MOUSE
θ value	0.0563607 (rank : 18)	NC score	0.053601 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	947	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DHX57_HUMAN
θ value	0.0563607 (rank : 19)	NC score	0.071560 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

NKRF_MOUSE
θ value	0.0563607 (rank : 20)	NC score	0.104444 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

K2C8_HUMAN
θ value	0.0736092 (rank : 21)	NC score	0.019451 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	593	Shared Neighborhood Hits	12
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

NKRF_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.096279 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O15226, Q9UJ91	Gene names	NKRF, ITBA4, NRF
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF) (ITBA4 protein).

ZFAN6_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.068810 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

K2C8_MOUSE
θ value	0.0961366 (rank : 24)	NC score	0.019044 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	576	Shared Neighborhood Hits	12
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

DHX36_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.058528 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

CCD96_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.024452 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	595	Shared Neighborhood Hits	15
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

FZD8_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.014408 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

TRP13_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.066715 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

BSN_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.032042 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	1537	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PEX6_MOUSE
θ value	0.365318 (rank : 30)	NC score	0.040569 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

TRP13_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.061382 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

DHX9_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.052803 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

AFAD_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.020589 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	689	Shared Neighborhood Hits	14
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PCDA4_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.006813 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

SRCA_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.024774 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	380	Shared Neighborhood Hits	18
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

AFF4_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.018419 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BAT2_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.046195 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DHX16_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.045340 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	356	Shared Neighborhood Hits	18
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

HME1_MOUSE
θ value	1.38821 (rank : 39)	NC score	0.007885 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	397	Shared Neighborhood Hits	6
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

K2C1_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.014046 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	624	Shared Neighborhood Hits	12
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

MYCN_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.019593 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

NBR1_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.034860 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

PCLO_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.017934 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	2275	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PEX6_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.034394 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

DHX8_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.044383 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

PRB3_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.023738 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

ANKS1_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.006507 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	438	Shared Neighborhood Hits	5
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

MBB1A_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.024687 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	665	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PEO1_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.045950 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

TTBK1_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.004810 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	1058	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

CRYL1_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.020669 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2S2, Q7Z4Z9	Gene names	CRYL1, CRY
Domain Architecture
Description	Lambda-crystallin homolog.

NBR1_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.031449 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

PEO1_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.043982 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

RGS3_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.014044 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	1621	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SASH1_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.016611 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SOX30_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.012361 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TTF1_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.021705 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	277	Shared Neighborhood Hits	13
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

ZFAN1_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.022545 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFR6, Q8R3Y6, Q9D7H5	Gene names	Zfand1
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 1.

ARI1A_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.019836 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	787	Shared Neighborhood Hits	22
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

DEDD2_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.016831 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXF8, Q8NBR2, Q8NES1, Q8TAA8, Q96D35	Gene names	DEDD2, FLAME3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

GLDN_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.008312 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

MAST2_HUMAN
θ value	4.03905 (rank : 62)	NC score	-0.000032 (rank : 114)
Query Neighborhood Hits	107	Target Neighborhood Hits	1189	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MTRR_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.020591 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

OGFR_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.016454 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	1582	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCDA4_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.005414 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	O88689, Q3UEX3, Q6PAM9, Q8K487, Q8K489	Gene names	Pcdha4, Cnr1
Domain Architecture	No domain graphic available
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

TCAL3_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.018355 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

VPS53_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.034947 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VIR6, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25	Gene names	VPS53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

VPS53_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.034332 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

CLMN_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.006665 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

K2C1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.013631 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	477	Shared Neighborhood Hits	11
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

NBN_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.015825 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

TCAL6_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.015827 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

TUB_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.010027 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P50607, O00293	Gene names	TUB
Domain Architecture
Description	Tubby protein homolog.

APXL_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.011510 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	553	Shared Neighborhood Hits	16
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BCAS1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.021068 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	10
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

BCAS1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.024805 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	215	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

CK5P2_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.005126 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	1433	Shared Neighborhood Hits	19
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CLIC6_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.015232 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	289	Shared Neighborhood Hits	19
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CUTL2_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.013689 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

HXA11_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.002801 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	P31311, Q3V026	Gene names	Hoxa11, Hox-1.9, Hoxa-11
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1.9).

LAD1_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.017784 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MAML1_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.012361 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

RFC5_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.043290 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.046015 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

SOX13_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.013691 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	495	Shared Neighborhood Hits	16
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TAU_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.017740 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	448	Shared Neighborhood Hits	21
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCOF_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.018323 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	471	Shared Neighborhood Hits	21
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TF3C1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.012526 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

UBP42_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.007374 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

ZBTB9_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.000460 (rank : 113)
Query Neighborhood Hits	107	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ZCH11_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.012458 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ZDH23_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.008669 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYP9	Gene names	ZDHHC23
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC23 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 23) (DHHC-23).

CO3A1_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.006402 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	452	Shared Neighborhood Hits	19
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CSKI1_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.006207 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	997	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTRO_MOUSE
θ value	8.99809 (rank : 95)	NC score	-0.000381 (rank : 115)
Query Neighborhood Hits	107	Target Neighborhood Hits	2344	Shared Neighborhood Hits	28
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DHX30_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.039818 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX34_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.039297 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DYHC_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.026541 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	733	Shared Neighborhood Hits	21
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.026655 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	729	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

OXRP_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.007906 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	544	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PCDA2_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.004709 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

PHC2_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.011055 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	388	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PLCG_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.007387 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q643R3, O43412, Q7Z4P4, Q8IUL7, Q8TB38	Gene names	AGPAT7, AYTL3
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase eta (EC 2.3.1.51) (1- AGP acyltransferase 7) (1-AGPAT 7) (Lysophosphatidic acid acyltransferase-eta) (LPAAT-eta) (Acyltransferase-like 3).

PRP1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.018152 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RAI1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.010838 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	360	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REST_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.003490 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	1506	Shared Neighborhood Hits	19
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TIF1B_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.006671 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

CX048_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.193632 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

RRP44_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.057291 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

SPR2B_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.059499 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.062831 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.055388 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2F_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.059383 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.060318 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.055597 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

Hits sorted by NC score

SMBP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
NC score	0.979198 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

RENT1_HUMAN
NC score	0.816993 (rank : 3)	θ value	2.18568e-46 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
NC score	0.816832 (rank : 4)	θ value	2.18568e-46 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

MOV10_MOUSE
NC score	0.723248 (rank : 5)	θ value	1.62847e-25 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

M10L1_HUMAN
NC score	0.722401 (rank : 6)	θ value	2.05525e-28 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

MOV10_HUMAN
NC score	0.721183 (rank : 7)	θ value	3.62785e-25 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

SETX_HUMAN
NC score	0.711939 (rank : 8)	θ value	1.9192e-34 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

PR285_HUMAN
NC score	0.708850 (rank : 9)	θ value	3.62785e-25 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

M10L1_MOUSE
NC score	0.708699 (rank : 10)	θ value	8.63488e-27 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

HELZ_HUMAN
NC score	0.628751 (rank : 11)	θ value	2.43908e-13 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

AQR_MOUSE
NC score	0.481119 (rank : 12)	θ value	2.13673e-09 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.478201 (rank : 13)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

ZNFX1_MOUSE
NC score	0.475915 (rank : 14)	θ value	1.29331e-14 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	407	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
NC score	0.471664 (rank : 15)	θ value	5.43371e-13 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CX048_HUMAN
NC score	0.193632 (rank : 16)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

NKRF_MOUSE
NC score	0.104444 (rank : 17)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

NKRF_HUMAN
NC score	0.096279 (rank : 18)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O15226, Q9UJ91	Gene names	NKRF, ITBA4, NRF
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF) (ITBA4 protein).

ZFAN6_HUMAN
NC score	0.081719 (rank : 19)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

DHX57_MOUSE
NC score	0.074412 (rank : 20)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_HUMAN
NC score	0.071560 (rank : 21)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ZFAN6_MOUSE
NC score	0.068810 (rank : 22)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

TRP13_HUMAN
NC score	0.066715 (rank : 23)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

SPR2D_MOUSE
NC score	0.062831 (rank : 24)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

TRP13_MOUSE
NC score	0.061382 (rank : 25)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

SPR2G_MOUSE
NC score	0.060318 (rank : 26)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2B_MOUSE
NC score	0.059499 (rank : 27)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2F_HUMAN
NC score	0.059383 (rank : 28)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	107	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

DHX36_MOUSE
NC score	0.058528 (rank : 29)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

RRP44_HUMAN
NC score	0.057291 (rank : 30)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

SPR2H_MOUSE
NC score	0.055597 (rank : 31)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	107	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2E_HUMAN
NC score	0.055388 (rank : 32)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

BAT2_MOUSE
NC score	0.053601 (rank : 33)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	947	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DHX9_HUMAN
NC score	0.052803 (rank : 34)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

BAT2_HUMAN
NC score	0.046195 (rank : 35)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RFC5_MOUSE
NC score	0.046015 (rank : 36)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

PEO1_HUMAN
NC score	0.045950 (rank : 37)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

DHX16_HUMAN
NC score	0.045340 (rank : 38)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	356	Shared Neighborhood Hits	18
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DHX8_HUMAN
NC score	0.044383 (rank : 39)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

PEO1_MOUSE
NC score	0.043982 (rank : 40)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

RFC5_HUMAN
NC score	0.043290 (rank : 41)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

PEX6_MOUSE
NC score	0.040569 (rank : 42)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

DHX30_MOUSE
NC score	0.039818 (rank : 43)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX34_HUMAN
NC score	0.039297 (rank : 44)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

VPS53_HUMAN
NC score	0.034947 (rank : 45)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VIR6, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25	Gene names	VPS53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

NBR1_MOUSE
NC score	0.034860 (rank : 46)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

PEX6_HUMAN
NC score	0.034394 (rank : 47)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

VPS53_MOUSE
NC score	0.034332 (rank : 48)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

BSN_HUMAN
NC score	0.032042 (rank : 49)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	1537	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NBR1_HUMAN
NC score	0.031449 (rank : 50)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

DYHC_MOUSE
NC score	0.026655 (rank : 51)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	729	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.026541 (rank : 52)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	733	Shared Neighborhood Hits	21
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

BCAS1_MOUSE
NC score	0.024805 (rank : 53)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	215	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

SRCA_HUMAN
NC score	0.024774 (rank : 54)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	380	Shared Neighborhood Hits	18
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

MBB1A_HUMAN
NC score	0.024687 (rank : 55)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	665	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CCD96_HUMAN
NC score	0.024452 (rank : 56)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	595	Shared Neighborhood Hits	15
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

PRB3_HUMAN
NC score	0.023738 (rank : 57)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

ZFAN1_MOUSE
NC score	0.022545 (rank : 58)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFR6, Q8R3Y6, Q9D7H5	Gene names	Zfand1
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 1.

TTF1_MOUSE
NC score	0.021705 (rank : 59)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	277	Shared Neighborhood Hits	13
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

BCAS1_HUMAN
NC score	0.021068 (rank : 60)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	10
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CRYL1_HUMAN
NC score	0.020669 (rank : 61)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2S2, Q7Z4Z9	Gene names	CRYL1, CRY
Domain Architecture
Description	Lambda-crystallin homolog.

MTRR_HUMAN
NC score	0.020591 (rank : 62)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

AFAD_HUMAN
NC score	0.020589 (rank : 63)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	689	Shared Neighborhood Hits	14
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ARI1A_HUMAN
NC score	0.019836 (rank : 64)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	787	Shared Neighborhood Hits	22
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MYCN_MOUSE
NC score	0.019593 (rank : 65)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

K2C8_HUMAN
NC score	0.019451 (rank : 66)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	593	Shared Neighborhood Hits	12
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

K2C8_MOUSE
NC score	0.019044 (rank : 67)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	576	Shared Neighborhood Hits	12
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

AFF4_MOUSE
NC score	0.018419 (rank : 68)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TCAL3_MOUSE
NC score	0.018355 (rank : 69)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TCOF_MOUSE
NC score	0.018323 (rank : 70)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	471	Shared Neighborhood Hits	21
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PRP1_HUMAN
NC score	0.018152 (rank : 71)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PCLO_MOUSE
NC score	0.017934 (rank : 72)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	2275	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LAD1_HUMAN
NC score	0.017784 (rank : 73)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

TAU_HUMAN
NC score	0.017740 (rank : 74)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	448	Shared Neighborhood Hits	21
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

DEDD2_HUMAN
NC score	0.016831 (rank : 75)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXF8, Q8NBR2, Q8NES1, Q8TAA8, Q96D35	Gene names	DEDD2, FLAME3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

SASH1_MOUSE
NC score	0.016611 (rank : 76)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

OGFR_HUMAN
NC score	0.016454 (rank : 77)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	1582	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TCAL6_HUMAN
NC score	0.015827 (rank : 78)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

NBN_MOUSE
NC score	0.015825 (rank : 79)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

CLIC6_HUMAN
NC score	0.015232 (rank : 80)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	289	Shared Neighborhood Hits	19
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

FZD8_MOUSE
NC score	0.014408 (rank : 81)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

K2C1_HUMAN
NC score	0.014046 (rank : 82)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	624	Shared Neighborhood Hits	12
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

RGS3_MOUSE
NC score	0.014044 (rank : 83)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	1621	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SOX13_MOUSE
NC score	0.013691 (rank : 84)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	495	Shared Neighborhood Hits	16
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

CUTL2_HUMAN
NC score	0.013689 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

K2C1_MOUSE
NC score	0.013631 (rank : 86)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	477	Shared Neighborhood Hits	11
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

TF3C1_HUMAN
NC score	0.012526 (rank : 87)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

ZCH11_HUMAN
NC score	0.012458 (rank : 88)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

SOX30_HUMAN
NC score	0.012361 (rank : 89)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

MAML1_MOUSE
NC score	0.012361 (rank : 90)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

APXL_HUMAN
NC score	0.011510 (rank : 91)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	553	Shared Neighborhood Hits	16
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PHC2_HUMAN
NC score	0.011055 (rank : 92)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	388	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

RAI1_HUMAN
NC score	0.010838 (rank : 93)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	360	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TUB_HUMAN
NC score	0.010027 (rank : 94)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P50607, O00293	Gene names	TUB
Domain Architecture
Description	Tubby protein homolog.

ZDH23_HUMAN
NC score	0.008669 (rank : 95)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYP9	Gene names	ZDHHC23
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC23 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 23) (DHHC-23).

GLDN_MOUSE
NC score	0.008312 (rank : 96)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

OXRP_HUMAN
NC score	0.007906 (rank : 97)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	544	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

HME1_MOUSE
NC score	0.007885 (rank : 98)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	397	Shared Neighborhood Hits	6
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

PLCG_HUMAN
NC score	0.007387 (rank : 99)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q643R3, O43412, Q7Z4P4, Q8IUL7, Q8TB38	Gene names	AGPAT7, AYTL3
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase eta (EC 2.3.1.51) (1- AGP acyltransferase 7) (1-AGPAT 7) (Lysophosphatidic acid acyltransferase-eta) (LPAAT-eta) (Acyltransferase-like 3).

UBP42_HUMAN
NC score	0.007374 (rank : 100)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

PCDA4_HUMAN
NC score	0.006813 (rank : 101)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

TIF1B_MOUSE
NC score	0.006671 (rank : 102)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

CLMN_MOUSE
NC score	0.006665 (rank : 103)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

ANKS1_HUMAN
NC score	0.006507 (rank : 104)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	438	Shared Neighborhood Hits	5
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CO3A1_HUMAN
NC score	0.006402 (rank : 105)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	452	Shared Neighborhood Hits	19
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CSKI1_HUMAN
NC score	0.006207 (rank : 106)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	997	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PCDA4_MOUSE
NC score	0.005414 (rank : 107)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	O88689, Q3UEX3, Q6PAM9, Q8K487, Q8K489	Gene names	Pcdha4, Cnr1
Domain Architecture	No domain graphic available
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

CK5P2_HUMAN
NC score	0.005126 (rank : 108)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	1433	Shared Neighborhood Hits	19
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

TTBK1_HUMAN
NC score	0.004810 (rank : 109)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	1058	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

PCDA2_HUMAN
NC score	0.004709 (rank : 110)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

REST_MOUSE
NC score	0.003490 (rank : 111)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	1506	Shared Neighborhood Hits	19
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

HXA11_MOUSE
NC score	0.002801 (rank : 112)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	P31311, Q3V026	Gene names	Hoxa11, Hox-1.9, Hoxa-11
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1.9).

ZBTB9_HUMAN
NC score	0.000460 (rank : 113)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

MAST2_HUMAN
NC score	-0.000032 (rank : 114)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	1189	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CTRO_MOUSE
NC score	-0.000381 (rank : 115)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	2344	Shared Neighborhood Hits	28
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).