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Network neighborhood for query Sequence : DHX8_HUMAN

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DHX8_HUMAN
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DHX16_HUMAN
θ value	0 (rank : 1)	NC score	0.947531 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	356	Shared Neighborhood Hits	39
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DHX8_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

PRP16_HUMAN
θ value	0 (rank : 3)	NC score	0.978906 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX15_HUMAN
θ value	3.96267e-181 (rank : 4)	NC score	0.984260 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
θ value	3.96267e-181 (rank : 5)	NC score	0.984124 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	52	Shared Neighborhood Hits	29
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX35_HUMAN
θ value	6.7907e-165 (rank : 6)	NC score	0.985095 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX33_MOUSE
θ value	2.11585e-158 (rank : 7)	NC score	0.979567 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX33_HUMAN
θ value	3.37801e-156 (rank : 8)	NC score	0.980118 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX40_MOUSE
θ value	1.28662e-147 (rank : 9)	NC score	0.976197 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX40_HUMAN
θ value	2.8663e-147 (rank : 10)	NC score	0.976596 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX34_MOUSE
θ value	5.85632e-100 (rank : 11)	NC score	0.945131 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX36_MOUSE
θ value	7.93343e-89 (rank : 12)	NC score	0.908000 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX30_HUMAN
θ value	1.07722e-69 (rank : 13)	NC score	0.919913 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
θ value	5.34618e-69 (rank : 14)	NC score	0.919306 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX9_HUMAN
θ value	5.17823e-64 (rank : 15)	NC score	0.907277 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX9_MOUSE
θ value	1.27544e-62 (rank : 16)	NC score	0.907887 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX36_HUMAN
θ value	2.57589e-55 (rank : 17)	NC score	0.910320 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX57_HUMAN
θ value	3.2585e-50 (rank : 18)	NC score	0.868734 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	109	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX29_MOUSE
θ value	9.48078e-50 (rank : 19)	NC score	0.875365 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	103	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX57_MOUSE
θ value	1.61718e-49 (rank : 20)	NC score	0.867564 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX37_HUMAN
θ value	1.15895e-47 (rank : 21)	NC score	0.911198 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	133	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DHX29_HUMAN
θ value	1.12253e-42 (rank : 22)	NC score	0.880265 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	144	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX34_HUMAN
θ value	1.12253e-42 (rank : 23)	NC score	0.926465 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

YTDC2_HUMAN
θ value	4.44505e-15 (rank : 24)	NC score	0.751131 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

NO40_MOUSE
θ value	5.26297e-08 (rank : 25)	NC score	0.138350 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESX4	Gene names	Zcchc17, Ps1d
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein).

NO40_HUMAN
θ value	6.87365e-08 (rank : 26)	NC score	0.138510 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP64, Q6PKH4, Q9NYG4, Q9P0M8	Gene names	ZCCHC17, PS1D
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein) (Pnn-interacting nucleolar protein).

CCD55_HUMAN
θ value	9.29e-05 (rank : 27)	NC score	0.092523 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	513	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ANR12_HUMAN
θ value	0.0252991 (rank : 28)	NC score	0.023220 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	1081	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SFRIP_HUMAN
θ value	0.0252991 (rank : 29)	NC score	0.051088 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	530	Shared Neighborhood Hits	22
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

NPBL_MOUSE
θ value	0.0330416 (rank : 30)	NC score	0.045876 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	1041	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RBBP6_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.032204 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CCD55_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.049267 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	519	Shared Neighborhood Hits	25
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

PPIL4_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.021654 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

CCD41_MOUSE
θ value	0.365318 (rank : 34)	NC score	0.011589 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MYH11_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.008007 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	1777	Shared Neighborhood Hits	29
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NIPBL_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.037425 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	1311	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SEPT9_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.010286 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SEPT9_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.011890 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

MDN1_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.028124 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	662	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RIMS1_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.008722 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	437	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

DPOLA_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.012673 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

HTF4_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.015083 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

HTF4_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.015234 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

NKTR_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.016734 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PPIG_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.020304 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

LEO1_MOUSE
θ value	1.81305 (rank : 46)	NC score	0.035693 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SMBP2_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.044383 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	107	Shared Neighborhood Hits	10
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.043088 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

OPTN_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.013230 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	827	Shared Neighborhood Hits	19
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

ABCAD_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.003533 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	150	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

GALT1_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.002802 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	O08912, Q5BKS3, Q7TND1	Gene names	Galnt1
Domain Architecture
Description	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) [Contains: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form].

MYH11_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.008303 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	1806	Shared Neighborhood Hits	31
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

DNPEP_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.011308 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULA0, Q9BW44, Q9NUV5	Gene names	DNPEP
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

LRRK2_HUMAN
θ value	4.03905 (rank : 54)	NC score	-0.001814 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	1382	Shared Neighborhood Hits	9
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

LRRK2_MOUSE
θ value	4.03905 (rank : 55)	NC score	-0.002340 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	1359	Shared Neighborhood Hits	8
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

UBP1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.008394 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	259	Shared Neighborhood Hits	9
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

CAC1C_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.002654 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CEBPG_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.008977 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

MY18A_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.011687 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	1989	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH14_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.006210 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	1225	Shared Neighborhood Hits	20
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

TRIO_HUMAN
θ value	5.27518 (rank : 61)	NC score	-0.002795 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	1580	Shared Neighborhood Hits	17
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

HECD2_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.002767 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

KTN1_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.002640 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	1197	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYH10_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.006850 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	1620	Shared Neighborhood Hits	22
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.007314 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	1612	Shared Neighborhood Hits	24
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH13_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.005140 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	1504	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYO9B_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.007474 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	311	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NOL3_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.010676 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	O60936, O60937	Gene names	NOL3, ARC, NOP
Domain Architecture
Description	Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30).

NUCB1_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.006132 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	414	Shared Neighborhood Hits	11
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

PNKP_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.025000 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

RBM15_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.007737 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	309	Shared Neighborhood Hits	13
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

SDCG1_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.010694 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

SK2L2_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.021837 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.023028 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SRPK1_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.000134 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	639	Shared Neighborhood Hits	7
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TARA_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.012712 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	1626	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CHM4A_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.005182 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BY43, Q32Q79, Q86SZ8, Q96QJ9, Q9P026	Gene names	CHMP4A, C14orf123, SHAX2
Domain Architecture
Description	Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (Vacuolar protein sorting 7-1) (SNF7-1) (hSnf-1) (SNF7 homolog associated with Alix-2).

DDX23_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.005425 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	486	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DNJC8_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.013591 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	380	Shared Neighborhood Hits	17
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

E41L1_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.001714 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

NUCB1_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.008138 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	359	Shared Neighborhood Hits	11
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

RNF6_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.003663 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

SRRM2_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.010727 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TR150_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.030852 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	468	Shared Neighborhood Hits	28
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

UBP8_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.003091 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	362	Shared Neighborhood Hits	13
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

ZEP2_HUMAN
θ value	8.99809 (rank : 86)	NC score	-0.002834 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	937	Shared Neighborhood Hits	8
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

Hits sorted by NC score

DHX8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX35_HUMAN
NC score	0.985095 (rank : 2)	θ value	6.7907e-165 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX15_HUMAN
NC score	0.984260 (rank : 3)	θ value	3.96267e-181 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
NC score	0.984124 (rank : 4)	θ value	3.96267e-181 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	52	Shared Neighborhood Hits	29
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX33_HUMAN
NC score	0.980118 (rank : 5)	θ value	3.37801e-156 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX33_MOUSE
NC score	0.979567 (rank : 6)	θ value	2.11585e-158 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

PRP16_HUMAN
NC score	0.978906 (rank : 7)	θ value	0 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX40_HUMAN
NC score	0.976596 (rank : 8)	θ value	2.8663e-147 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX40_MOUSE
NC score	0.976197 (rank : 9)	θ value	1.28662e-147 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX16_HUMAN
NC score	0.947531 (rank : 10)	θ value	0 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	356	Shared Neighborhood Hits	39
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DHX34_MOUSE
NC score	0.945131 (rank : 11)	θ value	5.85632e-100 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX34_HUMAN
NC score	0.926465 (rank : 12)	θ value	1.12253e-42 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX30_HUMAN
NC score	0.919913 (rank : 13)	θ value	1.07722e-69 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
NC score	0.919306 (rank : 14)	θ value	5.34618e-69 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX37_HUMAN
NC score	0.911198 (rank : 15)	θ value	1.15895e-47 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	133	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DHX36_HUMAN
NC score	0.910320 (rank : 16)	θ value	2.57589e-55 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_MOUSE
NC score	0.908000 (rank : 17)	θ value	7.93343e-89 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX9_MOUSE
NC score	0.907887 (rank : 18)	θ value	1.27544e-62 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX9_HUMAN
NC score	0.907277 (rank : 19)	θ value	5.17823e-64 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX29_HUMAN
NC score	0.880265 (rank : 20)	θ value	1.12253e-42 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	144	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX29_MOUSE
NC score	0.875365 (rank : 21)	θ value	9.48078e-50 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	103	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX57_HUMAN
NC score	0.868734 (rank : 22)	θ value	3.2585e-50 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	109	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
NC score	0.867564 (rank : 23)	θ value	1.61718e-49 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

YTDC2_HUMAN
NC score	0.751131 (rank : 24)	θ value	4.44505e-15 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

NO40_HUMAN
NC score	0.138510 (rank : 25)	θ value	6.87365e-08 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP64, Q6PKH4, Q9NYG4, Q9P0M8	Gene names	ZCCHC17, PS1D
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein) (Pnn-interacting nucleolar protein).

NO40_MOUSE
NC score	0.138350 (rank : 26)	θ value	5.26297e-08 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESX4	Gene names	Zcchc17, Ps1d
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein).

CCD55_HUMAN
NC score	0.092523 (rank : 27)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	513	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

SFRIP_HUMAN
NC score	0.051088 (rank : 28)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	530	Shared Neighborhood Hits	22
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CCD55_MOUSE
NC score	0.049267 (rank : 29)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	519	Shared Neighborhood Hits	25
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NPBL_MOUSE
NC score	0.045876 (rank : 30)	θ value	0.0330416 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	1041	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SMBP2_HUMAN
NC score	0.044383 (rank : 31)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	107	Shared Neighborhood Hits	10
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
NC score	0.043088 (rank : 32)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

NIPBL_HUMAN
NC score	0.037425 (rank : 33)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	1311	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

LEO1_MOUSE
NC score	0.035693 (rank : 34)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RBBP6_HUMAN
NC score	0.032204 (rank : 35)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TR150_MOUSE
NC score	0.030852 (rank : 36)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	468	Shared Neighborhood Hits	28
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

MDN1_HUMAN
NC score	0.028124 (rank : 37)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	662	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PNKP_MOUSE
NC score	0.025000 (rank : 38)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

ANR12_HUMAN
NC score	0.023220 (rank : 39)	θ value	0.0252991 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	1081	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SK2L2_MOUSE
NC score	0.023028 (rank : 40)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_HUMAN
NC score	0.021837 (rank : 41)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

PPIL4_HUMAN
NC score	0.021654 (rank : 42)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

PPIG_HUMAN
NC score	0.020304 (rank : 43)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

NKTR_MOUSE
NC score	0.016734 (rank : 44)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

HTF4_MOUSE
NC score	0.015234 (rank : 45)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

HTF4_HUMAN
NC score	0.015083 (rank : 46)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

DNJC8_HUMAN
NC score	0.013591 (rank : 47)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	380	Shared Neighborhood Hits	17
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

OPTN_HUMAN
NC score	0.013230 (rank : 48)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	827	Shared Neighborhood Hits	19
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

TARA_HUMAN
NC score	0.012712 (rank : 49)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	1626	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DPOLA_MOUSE
NC score	0.012673 (rank : 50)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

SEPT9_MOUSE
NC score	0.011890 (rank : 51)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

MY18A_MOUSE
NC score	0.011687 (rank : 52)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	1989	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD41_MOUSE
NC score	0.011589 (rank : 53)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DNPEP_HUMAN
NC score	0.011308 (rank : 54)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULA0, Q9BW44, Q9NUV5	Gene names	DNPEP
Domain Architecture
Description	Aspartyl aminopeptidase (EC 3.4.11.21).

SRRM2_MOUSE
NC score	0.010727 (rank : 55)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SDCG1_HUMAN
NC score	0.010694 (rank : 56)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

NOL3_HUMAN
NC score	0.010676 (rank : 57)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	O60936, O60937	Gene names	NOL3, ARC, NOP
Domain Architecture
Description	Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30).

SEPT9_HUMAN
NC score	0.010286 (rank : 58)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CEBPG_HUMAN
NC score	0.008977 (rank : 59)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

RIMS1_HUMAN
NC score	0.008722 (rank : 60)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	437	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

UBP1_HUMAN
NC score	0.008394 (rank : 61)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	259	Shared Neighborhood Hits	9
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

MYH11_HUMAN
NC score	0.008303 (rank : 62)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	1806	Shared Neighborhood Hits	31
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NUCB1_HUMAN
NC score	0.008138 (rank : 63)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	359	Shared Neighborhood Hits	11
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

MYH11_MOUSE
NC score	0.008007 (rank : 64)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	1777	Shared Neighborhood Hits	29
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RBM15_HUMAN
NC score	0.007737 (rank : 65)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	309	Shared Neighborhood Hits	13
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

MYO9B_MOUSE
NC score	0.007474 (rank : 66)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	311	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYH10_MOUSE
NC score	0.007314 (rank : 67)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	1612	Shared Neighborhood Hits	24
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.006850 (rank : 68)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	1620	Shared Neighborhood Hits	22
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH14_MOUSE
NC score	0.006210 (rank : 69)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	1225	Shared Neighborhood Hits	20
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NUCB1_MOUSE
NC score	0.006132 (rank : 70)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	414	Shared Neighborhood Hits	11
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

DDX23_HUMAN
NC score	0.005425 (rank : 71)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	486	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

CHM4A_HUMAN
NC score	0.005182 (rank : 72)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BY43, Q32Q79, Q86SZ8, Q96QJ9, Q9P026	Gene names	CHMP4A, C14orf123, SHAX2
Domain Architecture
Description	Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (Vacuolar protein sorting 7-1) (SNF7-1) (hSnf-1) (SNF7 homolog associated with Alix-2).

MYH13_HUMAN
NC score	0.005140 (rank : 73)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	1504	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

RNF6_HUMAN
NC score	0.003663 (rank : 74)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

ABCAD_MOUSE
NC score	0.003533 (rank : 75)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	150	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

UBP8_MOUSE
NC score	0.003091 (rank : 76)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	362	Shared Neighborhood Hits	13
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

GALT1_MOUSE
NC score	0.002802 (rank : 77)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	O08912, Q5BKS3, Q7TND1	Gene names	Galnt1
Domain Architecture
Description	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) [Contains: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form].

HECD2_HUMAN
NC score	0.002767 (rank : 78)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

CAC1C_MOUSE
NC score	0.002654 (rank : 79)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

KTN1_HUMAN
NC score	0.002640 (rank : 80)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	1197	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

E41L1_MOUSE
NC score	0.001714 (rank : 81)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

SRPK1_MOUSE
NC score	0.000134 (rank : 82)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	639	Shared Neighborhood Hits	7
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

LRRK2_HUMAN
NC score	-0.001814 (rank : 83)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	1382	Shared Neighborhood Hits	9
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

LRRK2_MOUSE
NC score	-0.002340 (rank : 84)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	1359	Shared Neighborhood Hits	8
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

TRIO_HUMAN
NC score	-0.002795 (rank : 85)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	1580	Shared Neighborhood Hits	17
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

ZEP2_HUMAN
NC score	-0.002834 (rank : 86)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	937	Shared Neighborhood Hits	8
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).