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Network neighborhood for query Sequence : E41L1_MOUSE

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E41L1_MOUSE
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E41L1_HUMAN
θ value	0 (rank : 1)	NC score	0.992845 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	180	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L2_HUMAN
θ value	0 (rank : 3)	NC score	0.973195 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	287	Shared Neighborhood Hits	57
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_MOUSE
θ value	0 (rank : 4)	NC score	0.977292 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	250	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_MOUSE
θ value	1.66487e-179 (rank : 5)	NC score	0.951410 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	459	Shared Neighborhood Hits	60
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_HUMAN
θ value	5.01279e-176 (rank : 6)	NC score	0.986219 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
θ value	4.56552e-153 (rank : 7)	NC score	0.980108 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
θ value	1.98498e-148 (rank : 8)	NC score	0.978343 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	184	Shared Neighborhood Hits	57
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTN4_HUMAN
θ value	4.35321e-87 (rank : 9)	NC score	0.677364 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	303	Shared Neighborhood Hits	50
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L5_HUMAN
θ value	8.51556e-75 (rank : 10)	NC score	0.963039 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
θ value	1.96316e-71 (rank : 11)	NC score	0.962126 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
θ value	2.83479e-70 (rank : 12)	NC score	0.956101 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41LA_HUMAN
θ value	1.40689e-69 (rank : 13)	NC score	0.956585 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP1_HUMAN
θ value	7.71989e-68 (rank : 14)	NC score	0.797372 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	241	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRMD5_HUMAN
θ value	2.24614e-67 (rank : 15)	NC score	0.959208 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_MOUSE
θ value	2.93355e-67 (rank : 16)	NC score	0.961686 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LA_MOUSE
θ value	3.24342e-66 (rank : 17)	NC score	0.956527 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP2_MOUSE
θ value	2.10232e-65 (rank : 18)	NC score	0.765233 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	1.15359e-63 (rank : 19)	NC score	0.773333 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN3_HUMAN
θ value	8.55514e-59 (rank : 20)	NC score	0.648053 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_MOUSE
θ value	2.19075e-38 (rank : 21)	NC score	0.618763 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	1.08726e-37 (rank : 22)	NC score	0.616994 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

EZRI_HUMAN
θ value	9.20422e-37 (rank : 23)	NC score	0.741507 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	663	Shared Neighborhood Hits	61
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	1.20211e-36 (rank : 24)	NC score	0.737138 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	693	Shared Neighborhood Hits	62
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_MOUSE
θ value	3.27365e-34 (rank : 25)	NC score	0.671083 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	923	Shared Neighborhood Hits	62
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	4.27553e-34 (rank : 26)	NC score	0.678357 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	892	Shared Neighborhood Hits	62
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RADI_HUMAN
θ value	4.27553e-34 (rank : 27)	NC score	0.720952 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	741	Shared Neighborhood Hits	61
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	4.27553e-34 (rank : 28)	NC score	0.717477 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	773	Shared Neighborhood Hits	63
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MERL_HUMAN
θ value	3.61944e-33 (rank : 29)	NC score	0.775145 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	532	Shared Neighborhood Hits	58
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	4.72714e-33 (rank : 30)	NC score	0.775589 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTN14_MOUSE
θ value	1.98606e-31 (rank : 31)	NC score	0.598816 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
θ value	6.38894e-30 (rank : 32)	NC score	0.590887 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

MYLIP_HUMAN
θ value	2.27234e-27 (rank : 33)	NC score	0.842679 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	5.06226e-27 (rank : 34)	NC score	0.857963 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN13_HUMAN
θ value	4.28545e-26 (rank : 35)	NC score	0.472332 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	471	Shared Neighborhood Hits	55
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	1.80048e-24 (rank : 36)	NC score	0.480860 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	426	Shared Neighborhood Hits	49
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

FRM4B_HUMAN
θ value	5.23862e-24 (rank : 37)	NC score	0.794102 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	6.84181e-24 (rank : 38)	NC score	0.791561 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
θ value	9.87957e-23 (rank : 39)	NC score	0.783206 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	1.6852e-22 (rank : 40)	NC score	0.781780 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

TLN2_HUMAN
θ value	9.59137e-10 (rank : 41)	NC score	0.417844 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	1.63604e-09 (rank : 42)	NC score	0.421766 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

FRMD6_HUMAN
θ value	6.21693e-09 (rank : 43)	NC score	0.656205 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
θ value	1.38499e-08 (rank : 44)	NC score	0.664480 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

TLN1_HUMAN
θ value	4.0297e-08 (rank : 45)	NC score	0.424122 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	218	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	4.0297e-08 (rank : 46)	NC score	0.420904 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

FRMD1_HUMAN
θ value	2.61198e-07 (rank : 47)	NC score	0.642289 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

NPBL_MOUSE
θ value	0.0113563 (rank : 48)	NC score	0.043759 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

GIT1_MOUSE
θ value	0.0431538 (rank : 49)	NC score	0.027040 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

US6NL_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.031109 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

TCP10_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.037905 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

CN145_MOUSE
θ value	0.125558 (rank : 52)	NC score	0.032724 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	916	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

IWS1_HUMAN
θ value	0.125558 (rank : 53)	NC score	0.044559 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TGON1_MOUSE
θ value	0.125558 (rank : 54)	NC score	0.044720 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

DNMT1_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.041602 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	401	Shared Neighborhood Hits	19
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

CN145_HUMAN
θ value	0.279714 (rank : 56)	NC score	0.036418 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	1196	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MDC1_HUMAN
θ value	0.279714 (rank : 57)	NC score	0.022634 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	1446	Shared Neighborhood Hits	37
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

UBN1_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.026728 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

DMP1_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.049661 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

NALP5_MOUSE
θ value	0.47712 (rank : 60)	NC score	0.017185 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	560	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

CUTL2_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.027348 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	906	Shared Neighborhood Hits	24
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

FOXN1_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.015705 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	300	Shared Neighborhood Hits	10
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

IWS1_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.043746 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	1258	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RBM25_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.038352 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	682	Shared Neighborhood Hits	32
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

K1143_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.043770 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AT1, Q96HJ8, Q9ULS7	Gene names	KIAA1143
Domain Architecture	No domain graphic available
Description	Protein KIAA1143.

LIPS_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.027903 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	13
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

RBM6_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.033260 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

YTDC1_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.025727 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

GIT1_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.020336 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

RU17_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.017258 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	280	Shared Neighborhood Hits	14
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

RU17_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.015272 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

ACINU_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.035682 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	828	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANR18_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.013714 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	1106	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

GEMI5_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.008047 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	424	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

K0240_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.009175 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

K1143_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.043297 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

SEC63_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.013991 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	586	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ZC313_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.043761 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ADDB_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.012441 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	574	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BEGIN_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.025147 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	383	Shared Neighborhood Hits	17
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CAN3_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.004853 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

DNJC9_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.006517 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WN1, Q3TSG3, Q8R0E3	Gene names	Dnajc9
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 9.

IF3A_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.030411 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	875	Shared Neighborhood Hits	36
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

LMO7_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.010909 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PRG4_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.007762 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	764	Shared Neighborhood Hits	15
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NCOR1_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.030737 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	521	Shared Neighborhood Hits	22
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

THSD1_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.015391 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TMF1_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.021730 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	987	Shared Neighborhood Hits	29
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

YLPM1_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.005319 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	505	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

3BP2_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.027363 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MCPH1_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.014258 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

CUTL2_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.012989 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	771	Shared Neighborhood Hits	16
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

LUZP1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.003513 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	739	Shared Neighborhood Hits	18
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MYO5C_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.017437 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	1206	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PALB2_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.005930 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

SFR12_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.021792 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	486	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

ZMYM3_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.005259 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ATRX_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.013995 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	682	Shared Neighborhood Hits	23
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CENPF_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.021376 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	1932	Shared Neighborhood Hits	36
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DHX8_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.001714 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

IASPP_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.002701 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	688	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KIF3A_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.018131 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	715	Shared Neighborhood Hits	23
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

RIMS2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.014598 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	342	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

TBCD2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.021571 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	419	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TF3C1_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.006835 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TGON2_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.031419 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

CA106_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.089416 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.088005 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CD45_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.097109 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	243	Shared Neighborhood Hits	13
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.101722 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

FGD1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.056477 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.054675 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.052532 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.051260 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD4_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.057941 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.058512 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.061573 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.057903 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.060190 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.059721 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.055340 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	809	Shared Neighborhood Hits	25
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.051861 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	959	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.057482 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	1016	Shared Neighborhood Hits	35
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.084694 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.078170 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MESD1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.052059 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.053529 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

PKHA6_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.053184 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	591	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.100465 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.100435 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.106841 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.106619 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.115586 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.112004 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.115506 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.115871 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.108540 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.107025 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.100000 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	646	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.098810 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	726	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.115741 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.116878 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.100359 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.100364 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.106698 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.106670 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.106959 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.108109 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.111657 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.111302 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.104904 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.104357 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.093240 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.093213 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.098001 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.064781 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	485	Shared Neighborhood Hits	9
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.062315 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.093596 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.093107 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.063154 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	489	Shared Neighborhood Hits	8
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.083426 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	231	Shared Neighborhood Hits	14
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.084105 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.100081 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.100480 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.083913 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.084631 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.078903 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	244	Shared Neighborhood Hits	8
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.079290 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.104188 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.103868 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.104609 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.102235 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.102578 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.066055 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.081147 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.081093 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.078982 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.099522 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.083816 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

Hits sorted by NC score

E41L1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.992845 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	180	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_HUMAN
NC score	0.986219 (rank : 3)	θ value	5.01279e-176 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
NC score	0.980108 (rank : 4)	θ value	4.56552e-153 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
NC score	0.978343 (rank : 5)	θ value	1.98498e-148 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	184	Shared Neighborhood Hits	57
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L3_MOUSE
NC score	0.977292 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	250	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.973195 (rank : 7)	θ value	0 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	287	Shared Neighborhood Hits	57
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L5_HUMAN
NC score	0.963039 (rank : 8)	θ value	8.51556e-75 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
NC score	0.962126 (rank : 9)	θ value	1.96316e-71 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FRMD5_MOUSE
NC score	0.961686 (rank : 10)	θ value	2.93355e-67 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.959208 (rank : 11)	θ value	2.24614e-67 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LA_HUMAN
NC score	0.956585 (rank : 12)	θ value	1.40689e-69 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.956527 (rank : 13)	θ value	3.24342e-66 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_HUMAN
NC score	0.956101 (rank : 14)	θ value	2.83479e-70 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L2_MOUSE
NC score	0.951410 (rank : 15)	θ value	1.66487e-179 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	459	Shared Neighborhood Hits	60
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.857963 (rank : 16)	θ value	5.06226e-27 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.842679 (rank : 17)	θ value	2.27234e-27 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FARP1_HUMAN
NC score	0.797372 (rank : 18)	θ value	7.71989e-68 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	241	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRM4B_HUMAN
NC score	0.794102 (rank : 19)	θ value	5.23862e-24 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.791561 (rank : 20)	θ value	6.84181e-24 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
NC score	0.783206 (rank : 21)	θ value	9.87957e-23 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.781780 (rank : 22)	θ value	1.6852e-22 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MERL_MOUSE
NC score	0.775589 (rank : 23)	θ value	4.72714e-33 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.775145 (rank : 24)	θ value	3.61944e-33 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	532	Shared Neighborhood Hits	58
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP2_HUMAN
NC score	0.773333 (rank : 25)	θ value	1.15359e-63 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.765233 (rank : 26)	θ value	2.10232e-65 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.741507 (rank : 27)	θ value	9.20422e-37 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	663	Shared Neighborhood Hits	61
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.737138 (rank : 28)	θ value	1.20211e-36 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	693	Shared Neighborhood Hits	62
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.720952 (rank : 29)	θ value	4.27553e-34 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	741	Shared Neighborhood Hits	61
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.717477 (rank : 30)	θ value	4.27553e-34 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	773	Shared Neighborhood Hits	63
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_HUMAN
NC score	0.678357 (rank : 31)	θ value	4.27553e-34 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	892	Shared Neighborhood Hits	62
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN4_HUMAN
NC score	0.677364 (rank : 32)	θ value	4.35321e-87 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	303	Shared Neighborhood Hits	50
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MOES_MOUSE
NC score	0.671083 (rank : 33)	θ value	3.27365e-34 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	923	Shared Neighborhood Hits	62
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD6_MOUSE
NC score	0.664480 (rank : 34)	θ value	1.38499e-08 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.656205 (rank : 35)	θ value	6.21693e-09 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN3_HUMAN
NC score	0.648053 (rank : 36)	θ value	8.55514e-59 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FRMD1_HUMAN
NC score	0.642289 (rank : 37)	θ value	2.61198e-07 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PTN21_MOUSE
NC score	0.618763 (rank : 38)	θ value	2.19075e-38 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.616994 (rank : 39)	θ value	1.08726e-37 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.598816 (rank : 40)	θ value	1.98606e-31 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.590887 (rank : 41)	θ value	6.38894e-30 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.480860 (rank : 42)	θ value	1.80048e-24 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	426	Shared Neighborhood Hits	49
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.472332 (rank : 43)	θ value	4.28545e-26 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	471	Shared Neighborhood Hits	55
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TLN1_HUMAN
NC score	0.424122 (rank : 44)	θ value	4.0297e-08 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	218	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.421766 (rank : 45)	θ value	1.63604e-09 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
NC score	0.420904 (rank : 46)	θ value	4.0297e-08 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.417844 (rank : 47)	θ value	9.59137e-10 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

PTN2_MOUSE
NC score	0.116878 (rank : 48)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.115871 (rank : 49)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN2_HUMAN
NC score	0.115741 (rank : 50)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_HUMAN
NC score	0.115586 (rank : 51)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN1_HUMAN
NC score	0.115506 (rank : 52)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_MOUSE
NC score	0.112004 (rank : 53)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.111657 (rank : 54)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.111302 (rank : 55)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.108540 (rank : 56)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.108109 (rank : 57)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN22_MOUSE
NC score	0.107025 (rank : 58)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN7_HUMAN
NC score	0.106959 (rank : 59)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_HUMAN
NC score	0.106841 (rank : 60)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN6_HUMAN
NC score	0.106698 (rank : 61)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.106670 (rank : 62)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN12_MOUSE
NC score	0.106619 (rank : 63)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPR2_HUMAN
NC score	0.104904 (rank : 64)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRO_HUMAN
NC score	0.104609 (rank : 65)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPR2_MOUSE
NC score	0.104357 (rank : 66)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_HUMAN
NC score	0.104188 (rank : 67)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.103868 (rank : 68)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_MOUSE
NC score	0.102578 (rank : 69)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.102235 (rank : 70)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CD45_MOUSE
NC score	0.101722 (rank : 71)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRJ_MOUSE
NC score	0.100480 (rank : 72)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN11_HUMAN
NC score	0.100465 (rank : 73)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.100435 (rank : 74)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN5_MOUSE
NC score	0.100364 (rank : 75)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.100359 (rank : 76)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRJ_HUMAN
NC score	0.100081 (rank : 77)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN23_HUMAN
NC score	0.100000 (rank : 78)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	646	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRV_MOUSE
NC score	0.099522 (rank : 79)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN23_MOUSE
NC score	0.098810 (rank : 80)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	726	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPRB_HUMAN
NC score	0.098001 (rank : 81)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

CD45_HUMAN
NC score	0.097109 (rank : 82)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	243	Shared Neighborhood Hits	13
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.093596 (rank : 83)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.093240 (rank : 84)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.093213 (rank : 85)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.093107 (rank : 86)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CA106_HUMAN
NC score	0.089416 (rank : 87)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.088005 (rank : 88)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

KRIT1_HUMAN
NC score	0.084694 (rank : 89)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTPRK_MOUSE
NC score	0.084631 (rank : 90)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRG_MOUSE
NC score	0.084105 (rank : 91)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRK_HUMAN
NC score	0.083913 (rank : 92)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRZ_HUMAN
NC score	0.083816 (rank : 93)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.083426 (rank : 94)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	231	Shared Neighborhood Hits	14
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_HUMAN
NC score	0.081147 (rank : 95)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.081093 (rank : 96)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRM_MOUSE
NC score	0.079290 (rank : 97)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.078982 (rank : 98)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_HUMAN
NC score	0.078903 (rank : 99)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	244	Shared Neighborhood Hits	8
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KRIT1_MOUSE
NC score	0.078170 (rank : 100)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTPRS_HUMAN
NC score	0.066055 (rank : 101)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.064781 (rank : 102)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	485	Shared Neighborhood Hits	9
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.063154 (rank : 103)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	489	Shared Neighborhood Hits	8
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.062315 (rank : 104)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FGD5_HUMAN
NC score	0.061573 (rank : 105)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD6_HUMAN
NC score	0.060190 (rank : 106)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.059721 (rank : 107)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD4_MOUSE
NC score	0.058512 (rank : 108)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD4_HUMAN
NC score	0.057941 (rank : 109)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD5_MOUSE
NC score	0.057903 (rank : 110)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

HIP1_HUMAN
NC score	0.057482 (rank : 111)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	1016	Shared Neighborhood Hits	35
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

FGD1_HUMAN
NC score	0.056477 (rank : 112)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HIP1R_HUMAN
NC score	0.055340 (rank : 113)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	809	Shared Neighborhood Hits	25
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

FGD1_MOUSE
NC score	0.054675 (rank : 114)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MESD1_MOUSE
NC score	0.053529 (rank : 115)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

PKHA6_MOUSE
NC score	0.053184 (rank : 116)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	591	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

FGD2_MOUSE
NC score	0.052532 (rank : 117)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

MESD1_HUMAN
NC score	0.052059 (rank : 118)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

HIP1R_MOUSE
NC score	0.051861 (rank : 119)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	959	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

FGD3_HUMAN
NC score	0.051260 (rank : 120)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

DMP1_HUMAN
NC score	0.049661 (rank : 121)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TGON1_MOUSE
NC score	0.044720 (rank : 122)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

IWS1_HUMAN
NC score	0.044559 (rank : 123)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1143_HUMAN
NC score	0.043770 (rank : 124)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AT1, Q96HJ8, Q9ULS7	Gene names	KIAA1143
Domain Architecture	No domain graphic available
Description	Protein KIAA1143.

ZC313_HUMAN
NC score	0.043761 (rank : 125)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

NPBL_MOUSE
NC score	0.043759 (rank : 126)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

IWS1_MOUSE
NC score	0.043746 (rank : 127)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	1258	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1143_MOUSE
NC score	0.043297 (rank : 128)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

DNMT1_HUMAN
NC score	0.041602 (rank : 129)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	401	Shared Neighborhood Hits	19
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

RBM25_HUMAN
NC score	0.038352 (rank : 130)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	682	Shared Neighborhood Hits	32
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TCP10_HUMAN
NC score	0.037905 (rank : 131)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

CN145_HUMAN
NC score	0.036418 (rank : 132)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	1196	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

ACINU_HUMAN
NC score	0.035682 (rank : 133)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	828	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RBM6_HUMAN
NC score	0.033260 (rank : 134)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

CN145_MOUSE
NC score	0.032724 (rank : 135)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	916	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

TGON2_MOUSE
NC score	0.031419 (rank : 136)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

US6NL_MOUSE
NC score	0.031109 (rank : 137)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

NCOR1_MOUSE
NC score	0.030737 (rank : 138)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	521	Shared Neighborhood Hits	22
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

IF3A_HUMAN
NC score	0.030411 (rank : 139)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	875	Shared Neighborhood Hits	36
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

LIPS_HUMAN
NC score	0.027903 (rank : 140)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	13
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

3BP2_MOUSE
NC score	0.027363 (rank : 141)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CUTL2_HUMAN
NC score	0.027348 (rank : 142)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	906	Shared Neighborhood Hits	24
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

GIT1_MOUSE
NC score	0.027040 (rank : 143)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

UBN1_HUMAN
NC score	0.026728 (rank : 144)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

YTDC1_HUMAN
NC score	0.025727 (rank : 145)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

BEGIN_MOUSE
NC score	0.025147 (rank : 146)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	383	Shared Neighborhood Hits	17
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

MDC1_HUMAN
NC score	0.022634 (rank : 147)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	1446	Shared Neighborhood Hits	37
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SFR12_MOUSE
NC score	0.021792 (rank : 148)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	486	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TMF1_HUMAN
NC score	0.021730 (rank : 149)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	987	Shared Neighborhood Hits	29
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TBCD2_HUMAN
NC score	0.021571 (rank : 150)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	419	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

CENPF_HUMAN
NC score	0.021376 (rank : 151)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	1932	Shared Neighborhood Hits	36
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GIT1_HUMAN
NC score	0.020336 (rank : 152)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

KIF3A_MOUSE
NC score	0.018131 (rank : 153)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	715	Shared Neighborhood Hits	23
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYO5C_HUMAN
NC score	0.017437 (rank : 154)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	1206	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RU17_HUMAN
NC score	0.017258 (rank : 155)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	280	Shared Neighborhood Hits	14
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

NALP5_MOUSE
NC score	0.017185 (rank : 156)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	560	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

FOXN1_MOUSE
NC score	0.015705 (rank : 157)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	300	Shared Neighborhood Hits	10
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

THSD1_MOUSE
NC score	0.015391 (rank : 158)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

RU17_MOUSE
NC score	0.015272 (rank : 159)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

RIMS2_HUMAN
NC score	0.014598 (rank : 160)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	342	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

MCPH1_MOUSE
NC score	0.014258 (rank : 161)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

ATRX_MOUSE
NC score	0.013995 (rank : 162)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	682	Shared Neighborhood Hits	23
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SEC63_HUMAN
NC score	0.013991 (rank : 163)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	586	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ANR18_HUMAN
NC score	0.013714 (rank : 164)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	1106	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CUTL2_MOUSE
NC score	0.012989 (rank : 165)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	771	Shared Neighborhood Hits	16
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ADDB_MOUSE
NC score	0.012441 (rank : 166)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	574	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

LMO7_HUMAN
NC score	0.010909 (rank : 167)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

K0240_MOUSE
NC score	0.009175 (rank : 168)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

GEMI5_MOUSE
NC score	0.008047 (rank : 169)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	424	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

PRG4_HUMAN
NC score	0.007762 (rank : 170)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	764	Shared Neighborhood Hits	15
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TF3C1_MOUSE
NC score	0.006835 (rank : 171)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

DNJC9_MOUSE
NC score	0.006517 (rank : 172)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WN1, Q3TSG3, Q8R0E3	Gene names	Dnajc9
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 9.

PALB2_HUMAN
NC score	0.005930 (rank : 173)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

YLPM1_MOUSE
NC score	0.005319 (rank : 174)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	505	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZMYM3_HUMAN
NC score	0.005259 (rank : 175)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

CAN3_MOUSE
NC score	0.004853 (rank : 176)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

LUZP1_HUMAN
NC score	0.003513 (rank : 177)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	739	Shared Neighborhood Hits	18
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

IASPP_HUMAN
NC score	0.002701 (rank : 178)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	688	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

DHX8_HUMAN
NC score	0.001714 (rank : 179)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).