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Network neighborhood for query Sequence : TLN2_MOUSE

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TLN2_MOUSE
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TLN1_HUMAN
θ value	0 (rank : 1)	NC score	0.980030 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	218	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	0 (rank : 2)	NC score	0.978933 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	213	Shared Neighborhood Hits	80
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
θ value	0 (rank : 3)	NC score	0.996891 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

MESD1_MOUSE
θ value	1.09232e-21 (rank : 5)	NC score	0.577882 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_HUMAN
θ value	2.06002e-20 (rank : 6)	NC score	0.567043 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

HIP1_HUMAN
θ value	1.13037e-18 (rank : 7)	NC score	0.259097 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HIP1R_HUMAN
θ value	5.60996e-18 (rank : 8)	NC score	0.311657 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	809	Shared Neighborhood Hits	47
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	7.32683e-18 (rank : 9)	NC score	0.276821 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	959	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

RADI_HUMAN
θ value	6.64225e-11 (rank : 10)	NC score	0.407728 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	741	Shared Neighborhood Hits	88
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	6.64225e-11 (rank : 11)	NC score	0.406840 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	773	Shared Neighborhood Hits	88
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

E41L5_HUMAN
θ value	1.133e-10 (rank : 12)	NC score	0.442155 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LA_MOUSE
θ value	1.9326e-10 (rank : 13)	NC score	0.452980 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_HUMAN
θ value	3.29651e-10 (rank : 14)	NC score	0.439650 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

MYO7A_HUMAN
θ value	3.29651e-10 (rank : 15)	NC score	0.126826 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	209	Shared Neighborhood Hits	37
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	4.30538e-10 (rank : 16)	NC score	0.127430 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

EZRI_MOUSE
θ value	9.59137e-10 (rank : 17)	NC score	0.407237 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	693	Shared Neighborhood Hits	83
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_HUMAN
θ value	9.59137e-10 (rank : 18)	NC score	0.383114 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	892	Shared Neighborhood Hits	89
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	9.59137e-10 (rank : 19)	NC score	0.379884 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	923	Shared Neighborhood Hits	90
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PKHC1_HUMAN
θ value	9.59137e-10 (rank : 20)	NC score	0.342896 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

E41LA_HUMAN
θ value	1.25267e-09 (rank : 21)	NC score	0.446148 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PKHC1_MOUSE
θ value	1.25267e-09 (rank : 22)	NC score	0.340630 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

E41L1_HUMAN
θ value	1.63604e-09 (rank : 23)	NC score	0.419273 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
θ value	1.63604e-09 (rank : 24)	NC score	0.421766 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

EZRI_HUMAN
θ value	1.63604e-09 (rank : 25)	NC score	0.406552 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	663	Shared Neighborhood Hits	78
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTN4_HUMAN
θ value	2.13673e-09 (rank : 26)	NC score	0.310671 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	303	Shared Neighborhood Hits	52
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MERL_HUMAN
θ value	3.64472e-09 (rank : 27)	NC score	0.435206 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	532	Shared Neighborhood Hits	80
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	3.64472e-09 (rank : 28)	NC score	0.436298 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	524	Shared Neighborhood Hits	79
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

E41LB_MOUSE
θ value	4.76016e-09 (rank : 29)	NC score	0.437893 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

URP1_HUMAN
θ value	4.76016e-09 (rank : 30)	NC score	0.330514 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQL6, Q8IX34, Q8IYH2, Q9NWM2, Q9NXQ3	Gene names	URP1, C20orf42, KIND1
Domain Architecture
Description	Unc-112-related protein 1 (Kindlin-1) (Kindlerin) (Kindlin syndrome protein).

URP2_HUMAN
θ value	1.38499e-08 (rank : 31)	NC score	0.325002 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

URP2_MOUSE
θ value	1.38499e-08 (rank : 32)	NC score	0.323232 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

PTN3_HUMAN
θ value	3.08544e-08 (rank : 33)	NC score	0.297967 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

41_MOUSE
θ value	8.97725e-08 (rank : 34)	NC score	0.415988 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	184	Shared Neighborhood Hits	54
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTN13_MOUSE
θ value	1.17247e-07 (rank : 35)	NC score	0.254710 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	426	Shared Neighborhood Hits	57
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

41_HUMAN
θ value	1.53129e-07 (rank : 36)	NC score	0.412962 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L3_HUMAN
θ value	1.99992e-07 (rank : 37)	NC score	0.412279 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

KRIT1_HUMAN
θ value	7.59969e-07 (rank : 38)	NC score	0.208038 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

E41L3_MOUSE
θ value	9.92553e-07 (rank : 39)	NC score	0.402841 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

KRIT1_MOUSE
θ value	1.69304e-06 (rank : 40)	NC score	0.197933 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTN13_HUMAN
θ value	1.69304e-06 (rank : 41)	NC score	0.241347 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	471	Shared Neighborhood Hits	55
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

E41L2_HUMAN
θ value	4.92598e-06 (rank : 42)	NC score	0.400174 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	287	Shared Neighborhood Hits	59
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FRMD6_MOUSE
θ value	4.1701e-05 (rank : 43)	NC score	0.331253 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRM4A_HUMAN
θ value	0.000121331 (rank : 44)	NC score	0.371338 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD5_MOUSE
θ value	0.000121331 (rank : 45)	NC score	0.408520 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L2_MOUSE
θ value	0.00020696 (rank : 46)	NC score	0.380285 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	459	Shared Neighborhood Hits	59
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FRM4A_MOUSE
θ value	0.00020696 (rank : 47)	NC score	0.370835 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD5_HUMAN
θ value	0.00020696 (rank : 48)	NC score	0.408358 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRM4B_HUMAN
θ value	0.000270298 (rank : 49)	NC score	0.367989 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	0.000786445 (rank : 50)	NC score	0.360718 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRMD6_HUMAN
θ value	0.000786445 (rank : 51)	NC score	0.323875 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN14_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.250040 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	142	Shared Neighborhood Hits	51
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

MYLIP_MOUSE
θ value	0.00665767 (rank : 53)	NC score	0.368884 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN21_MOUSE
θ value	0.0148317 (rank : 54)	NC score	0.254122 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

MYLIP_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.346572 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

VINC_HUMAN
θ value	0.0193708 (rank : 56)	NC score	0.117332 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	145	Shared Neighborhood Hits	22
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	0.0193708 (rank : 57)	NC score	0.113376 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

PTN21_HUMAN
θ value	0.0563607 (rank : 58)	NC score	0.246581 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	143	Shared Neighborhood Hits	52
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

DOK4_HUMAN
θ value	0.0736092 (rank : 59)	NC score	0.094858 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
θ value	0.0736092 (rank : 60)	NC score	0.094712 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DYHC_HUMAN
θ value	0.0961366 (rank : 61)	NC score	0.049781 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	733	Shared Neighborhood Hits	39
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.0961366 (rank : 62)	NC score	0.049783 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	729	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

MYO10_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.062294 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	920	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PTN14_HUMAN
θ value	0.0961366 (rank : 64)	NC score	0.241628 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

CLC4F_MOUSE
θ value	0.21417 (rank : 65)	NC score	0.041400 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	572	Shared Neighborhood Hits	37
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

ATX7_MOUSE
θ value	0.365318 (rank : 66)	NC score	0.045768 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	328	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

MACF1_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.035430 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	1341	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.042528 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	1321	Shared Neighborhood Hits	58
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

ELOA1_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.027511 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	388	Shared Neighborhood Hits	5
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

LAMA3_HUMAN
θ value	0.47712 (rank : 70)	NC score	0.036092 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	760	Shared Neighborhood Hits	43
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MACF1_MOUSE
θ value	0.47712 (rank : 71)	NC score	0.039764 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	1313	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

GOGA2_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.047189 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	856	Shared Neighborhood Hits	42
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

M6PBP_HUMAN
θ value	0.62314 (rank : 73)	NC score	0.075401 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	O60664, Q53G77, Q9BS03, Q9UBD7, Q9UP92	Gene names	M6PRBP1, TIP47
Domain Architecture
Description	Mannose-6-phosphate receptor-binding protein 1 (Cargo selection protein TIP47) (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Placental protein 17) (PP17).

BRCA2_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.019053 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CU013_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.032461 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	405	Shared Neighborhood Hits	24
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

DOK6_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.052281 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

FARP2_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.274653 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	209	Shared Neighborhood Hits	46
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

K0372_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.032177 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

TSNA1_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.056692 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

FARP2_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.271712 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MYO1B_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.037366 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1B_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.037443 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

CDT1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.052140 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

CP250_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.045483 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	1805	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CTNA1_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.057934 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	P35221, Q12795	Gene names	CTNNA1
Domain Architecture
Description	Catenin alpha-1 (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen).

CTNA1_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.058121 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	P26231	Gene names	Ctnna1, Catna1
Domain Architecture
Description	Catenin alpha-1 (102 kDa cadherin-associated protein) (CAP102) (Alpha E-catenin).

DGKD_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.015822 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

FARP1_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.282954 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

K1C16_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.014580 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

NOS1_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.021873 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NPTX1_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.020517 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q15818, Q5FWE6	Gene names	NPTX1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NPTX1_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.020731 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q62443	Gene names	Nptx1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

CP250_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.043086 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	1583	Shared Neighborhood Hits	56
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

PKP4_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.013783 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

SI1L1_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.020410 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SIPA1_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.020810 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	250	Shared Neighborhood Hits	18
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SMC2_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.050453 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	1131	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

AFTIN_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.014482 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WT5, Q5SSE6, Q99KJ1	Gene names	Aftph, Afth
Domain Architecture	No domain graphic available
Description	Aftiphilin.

DYXC1_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.010886 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

FA49A_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.017299 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0Q0	Gene names	FAM49A
Domain Architecture	No domain graphic available
Description	Protein FAM49A.

FA49A_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.017295 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHZ0	Gene names	Fam49a, D12Ertd553e
Domain Architecture	No domain graphic available
Description	Protein FAM49A.

LAMA2_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.034607 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	1198	Shared Neighborhood Hits	46
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MDC1_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.015534 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	1446	Shared Neighborhood Hits	30
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PKP4_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.011188 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

RABE1_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.037408 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	1104	Shared Neighborhood Hits	53
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RAPH1_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.023019 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	593	Shared Neighborhood Hits	19
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RNF6_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.020286 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

ARI1A_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.006985 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	787	Shared Neighborhood Hits	10
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CCHCR_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.040257 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	932	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CLAP2_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.011279 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

GNAS1_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.005677 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	651	Shared Neighborhood Hits	13
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

JHD2A_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.010099 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

NEB2_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.049125 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	883	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.047252 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	889	Shared Neighborhood Hits	43
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

OPTN_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.044046 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	1120	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

SYNE2_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.028547 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	1323	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CTNA3_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.028240 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UI47, Q5VSR2, Q6P056	Gene names	CTNNA3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

DOK5_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.040072 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK5_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.040007 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DPOLZ_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.015070 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

GOGA2_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.048078 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	944	Shared Neighborhood Hits	49
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

IPP1_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.015539 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q13522, Q8TBJ2	Gene names	PPP1R1A, IPP1
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

ITA4_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.008683 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P13612	Gene names	ITGA4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49d antigen).

K1219_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.018111 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KI13B_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.007438 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	492	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LAMA4_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.028172 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	708	Shared Neighborhood Hits	36
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.011086 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	828	Shared Neighborhood Hits	25
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MET7B_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.044034 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

NEUM_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.022766 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NHS_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.013539 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

SYNE1_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.030910 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	1484	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

EP300_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.003535 (rank : 154)
Query Neighborhood Hits	149	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

KCNH2_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.003273 (rank : 155)
Query Neighborhood Hits	149	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MRCKB_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.019259 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	2239	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH10_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.043463 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	1620	Shared Neighborhood Hits	56
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.042372 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	1612	Shared Neighborhood Hits	56
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.045706 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	1806	Shared Neighborhood Hits	62
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

USH2A_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.006166 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	600	Shared Neighborhood Hits	11
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ZN687_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.004791 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	1244	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CASP_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.043721 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	1152	Shared Neighborhood Hits	47
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CKAP5_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.012265 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

DGKZ_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.005266 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	551	Shared Neighborhood Hits	7
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

FANCJ_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.005476 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

FRMD1_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.274050 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

KTN1_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.042117 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	1324	Shared Neighborhood Hits	51
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

OXR1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.038357 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	516	Shared Neighborhood Hits	24
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PAPD5_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.006474 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDF8, Q9NW67, Q9Y6C0	Gene names	PAPD5
Domain Architecture	No domain graphic available
Description	PAP-associated domain-containing protein 5 (EC 2.7.7.-) (Topoisomerase-related function protein 4-2) (TRF4-2).

SMC2_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.040912 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	1405	Shared Neighborhood Hits	50
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TAF4_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.020355 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	687	Shared Neighborhood Hits	25
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CCD11_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.061211 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	822	Shared Neighborhood Hits	41
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CROCC_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.050993 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	1460	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.053183 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	1434	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MYH8_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.051309 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	1600	Shared Neighborhood Hits	63
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NUMA1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.055138 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	1523	Shared Neighborhood Hits	63
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

TPM4_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.050342 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	703	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

Hits sorted by NC score

TLN2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.996891 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN1_HUMAN
NC score	0.980030 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	218	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.978933 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	213	Shared Neighborhood Hits	80
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

MESD1_MOUSE
NC score	0.577882 (rank : 5)	θ value	1.09232e-21 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_HUMAN
NC score	0.567043 (rank : 6)	θ value	2.06002e-20 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

E41LA_MOUSE
NC score	0.452980 (rank : 7)	θ value	1.9326e-10 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_HUMAN
NC score	0.446148 (rank : 8)	θ value	1.25267e-09 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L5_HUMAN
NC score	0.442155 (rank : 9)	θ value	1.133e-10 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_HUMAN
NC score	0.439650 (rank : 10)	θ value	3.29651e-10 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41LB_MOUSE
NC score	0.437893 (rank : 11)	θ value	4.76016e-09 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

MERL_MOUSE
NC score	0.436298 (rank : 12)	θ value	3.64472e-09 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	524	Shared Neighborhood Hits	79
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.435206 (rank : 13)	θ value	3.64472e-09 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	532	Shared Neighborhood Hits	80
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

E41L1_MOUSE
NC score	0.421766 (rank : 14)	θ value	1.63604e-09 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.419273 (rank : 15)	θ value	1.63604e-09 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_MOUSE
NC score	0.415988 (rank : 16)	θ value	8.97725e-08 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	184	Shared Neighborhood Hits	54
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

41_HUMAN
NC score	0.412962 (rank : 17)	θ value	1.53129e-07 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L3_HUMAN
NC score	0.412279 (rank : 18)	θ value	1.99992e-07 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

FRMD5_MOUSE
NC score	0.408520 (rank : 19)	θ value	0.000121331 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.408358 (rank : 20)	θ value	0.00020696 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

RADI_HUMAN
NC score	0.407728 (rank : 21)	θ value	6.64225e-11 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	741	Shared Neighborhood Hits	88
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

EZRI_MOUSE
NC score	0.407237 (rank : 22)	θ value	9.59137e-10 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	693	Shared Neighborhood Hits	83
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_MOUSE
NC score	0.406840 (rank : 23)	θ value	6.64225e-11 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	773	Shared Neighborhood Hits	88
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

EZRI_HUMAN
NC score	0.406552 (rank : 24)	θ value	1.63604e-09 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	663	Shared Neighborhood Hits	78
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

E41L3_MOUSE
NC score	0.402841 (rank : 25)	θ value	9.92553e-07 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.400174 (rank : 26)	θ value	4.92598e-06 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	287	Shared Neighborhood Hits	59
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MOES_HUMAN
NC score	0.383114 (rank : 27)	θ value	9.59137e-10 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	892	Shared Neighborhood Hits	89
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

E41L2_MOUSE
NC score	0.380285 (rank : 28)	θ value	0.00020696 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	459	Shared Neighborhood Hits	59
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MOES_MOUSE
NC score	0.379884 (rank : 29)	θ value	9.59137e-10 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	923	Shared Neighborhood Hits	90
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRM4A_HUMAN
NC score	0.371338 (rank : 30)	θ value	0.000121331 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
NC score	0.370835 (rank : 31)	θ value	0.00020696 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MYLIP_MOUSE
NC score	0.368884 (rank : 32)	θ value	0.00665767 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_HUMAN
NC score	0.367989 (rank : 33)	θ value	0.000270298 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.360718 (rank : 34)	θ value	0.000786445 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

MYLIP_HUMAN
NC score	0.346572 (rank : 35)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PKHC1_HUMAN
NC score	0.342896 (rank : 36)	θ value	9.59137e-10 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

PKHC1_MOUSE
NC score	0.340630 (rank : 37)	θ value	1.25267e-09 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

FRMD6_MOUSE
NC score	0.331253 (rank : 38)	θ value	4.1701e-05 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

URP1_HUMAN
NC score	0.330514 (rank : 39)	θ value	4.76016e-09 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQL6, Q8IX34, Q8IYH2, Q9NWM2, Q9NXQ3	Gene names	URP1, C20orf42, KIND1
Domain Architecture
Description	Unc-112-related protein 1 (Kindlin-1) (Kindlerin) (Kindlin syndrome protein).

URP2_HUMAN
NC score	0.325002 (rank : 40)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

FRMD6_HUMAN
NC score	0.323875 (rank : 41)	θ value	0.000786445 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

URP2_MOUSE
NC score	0.323232 (rank : 42)	θ value	1.38499e-08 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

HIP1R_HUMAN
NC score	0.311657 (rank : 43)	θ value	5.60996e-18 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	809	Shared Neighborhood Hits	47
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

PTN4_HUMAN
NC score	0.310671 (rank : 44)	θ value	2.13673e-09 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	303	Shared Neighborhood Hits	52
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.297967 (rank : 45)	θ value	3.08544e-08 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FARP1_HUMAN
NC score	0.282954 (rank : 46)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

HIP1R_MOUSE
NC score	0.276821 (rank : 47)	θ value	7.32683e-18 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	959	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

FARP2_MOUSE
NC score	0.274653 (rank : 48)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	209	Shared Neighborhood Hits	46
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FRMD1_HUMAN
NC score	0.274050 (rank : 49)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

FARP2_HUMAN
NC score	0.271712 (rank : 50)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

HIP1_HUMAN
NC score	0.259097 (rank : 51)	θ value	1.13037e-18 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

PTN13_MOUSE
NC score	0.254710 (rank : 52)	θ value	1.17247e-07 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	426	Shared Neighborhood Hits	57
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN21_MOUSE
NC score	0.254122 (rank : 53)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_MOUSE
NC score	0.250040 (rank : 54)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	142	Shared Neighborhood Hits	51
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
NC score	0.246581 (rank : 55)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	143	Shared Neighborhood Hits	52
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_HUMAN
NC score	0.241628 (rank : 56)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_HUMAN
NC score	0.241347 (rank : 57)	θ value	1.69304e-06 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	471	Shared Neighborhood Hits	55
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

KRIT1_HUMAN
NC score	0.208038 (rank : 58)	θ value	7.59969e-07 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
NC score	0.197933 (rank : 59)	θ value	1.69304e-06 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MYO7A_MOUSE
NC score	0.127430 (rank : 60)	θ value	4.30538e-10 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.126826 (rank : 61)	θ value	3.29651e-10 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	209	Shared Neighborhood Hits	37
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

VINC_HUMAN
NC score	0.117332 (rank : 62)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	145	Shared Neighborhood Hits	22
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
NC score	0.113376 (rank : 63)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

DOK4_HUMAN
NC score	0.094858 (rank : 64)	θ value	0.0736092 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
NC score	0.094712 (rank : 65)	θ value	0.0736092 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

M6PBP_HUMAN
NC score	0.075401 (rank : 66)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	O60664, Q53G77, Q9BS03, Q9UBD7, Q9UP92	Gene names	M6PRBP1, TIP47
Domain Architecture
Description	Mannose-6-phosphate receptor-binding protein 1 (Cargo selection protein TIP47) (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Placental protein 17) (PP17).

MYO10_HUMAN
NC score	0.062294 (rank : 67)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	920	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CCD11_HUMAN
NC score	0.061211 (rank : 68)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	822	Shared Neighborhood Hits	41
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CTNA1_MOUSE
NC score	0.058121 (rank : 69)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	P26231	Gene names	Ctnna1, Catna1
Domain Architecture
Description	Catenin alpha-1 (102 kDa cadherin-associated protein) (CAP102) (Alpha E-catenin).

CTNA1_HUMAN
NC score	0.057934 (rank : 70)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	P35221, Q12795	Gene names	CTNNA1
Domain Architecture
Description	Catenin alpha-1 (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen).

TSNA1_HUMAN
NC score	0.056692 (rank : 71)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

NUMA1_HUMAN
NC score	0.055138 (rank : 72)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	149	Target Neighborhood Hits	1523	Shared Neighborhood Hits	63
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

GOGA5_MOUSE
NC score	0.053183 (rank : 73)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	1434	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

DOK6_HUMAN
NC score	0.052281 (rank : 74)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

CDT1_HUMAN
NC score	0.052140 (rank : 75)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

MYH8_MOUSE
NC score	0.051309 (rank : 76)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	1600	Shared Neighborhood Hits	63
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CROCC_MOUSE
NC score	0.050993 (rank : 77)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	1460	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SMC2_MOUSE
NC score	0.050453 (rank : 78)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	1131	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

TPM4_MOUSE
NC score	0.050342 (rank : 79)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	149	Target Neighborhood Hits	703	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

DYHC_MOUSE
NC score	0.049783 (rank : 80)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	729	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.049781 (rank : 81)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	733	Shared Neighborhood Hits	39
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

NEB2_HUMAN
NC score	0.049125 (rank : 82)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	883	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

GOGA2_MOUSE
NC score	0.048078 (rank : 83)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	944	Shared Neighborhood Hits	49
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

NEB2_MOUSE
NC score	0.047252 (rank : 84)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	889	Shared Neighborhood Hits	43
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

GOGA2_HUMAN
NC score	0.047189 (rank : 85)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	856	Shared Neighborhood Hits	42
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

ATX7_MOUSE
NC score	0.045768 (rank : 86)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	328	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

MYH11_HUMAN
NC score	0.045706 (rank : 87)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	1806	Shared Neighborhood Hits	62
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CP250_HUMAN
NC score	0.045483 (rank : 88)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	1805	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

OPTN_MOUSE
NC score	0.044046 (rank : 89)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	1120	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

MET7B_MOUSE
NC score	0.044034 (rank : 90)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

CASP_MOUSE
NC score	0.043721 (rank : 91)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	1152	Shared Neighborhood Hits	47
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

MYH10_HUMAN
NC score	0.043463 (rank : 92)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	1620	Shared Neighborhood Hits	56
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CP250_MOUSE
NC score	0.043086 (rank : 93)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	1583	Shared Neighborhood Hits	56
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MACF4_HUMAN
NC score	0.042528 (rank : 94)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	1321	Shared Neighborhood Hits	58
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYH10_MOUSE
NC score	0.042372 (rank : 95)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	1612	Shared Neighborhood Hits	56
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

KTN1_MOUSE
NC score	0.042117 (rank : 96)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	1324	Shared Neighborhood Hits	51
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

CLC4F_MOUSE
NC score	0.041400 (rank : 97)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	572	Shared Neighborhood Hits	37
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

SMC2_HUMAN
NC score	0.040912 (rank : 98)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	1405	Shared Neighborhood Hits	50
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CCHCR_MOUSE
NC score	0.040257 (rank : 99)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	932	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

DOK5_HUMAN
NC score	0.040072 (rank : 100)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK5_MOUSE
NC score	0.040007 (rank : 101)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

MACF1_MOUSE
NC score	0.039764 (rank : 102)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	1313	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

OXR1_MOUSE
NC score	0.038357 (rank : 103)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	516	Shared Neighborhood Hits	24
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

MYO1B_MOUSE
NC score	0.037443 (rank : 104)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

RABE1_HUMAN
NC score	0.037408 (rank : 105)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	1104	Shared Neighborhood Hits	53
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

MYO1B_HUMAN
NC score	0.037366 (rank : 106)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

LAMA3_HUMAN
NC score	0.036092 (rank : 107)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	760	Shared Neighborhood Hits	43
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MACF1_HUMAN
NC score	0.035430 (rank : 108)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	1341	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

LAMA2_MOUSE
NC score	0.034607 (rank : 109)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	1198	Shared Neighborhood Hits	46
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CU013_HUMAN
NC score	0.032461 (rank : 110)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	405	Shared Neighborhood Hits	24
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

K0372_HUMAN
NC score	0.032177 (rank : 111)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

SYNE1_HUMAN
NC score	0.030910 (rank : 112)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	1484	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
NC score	0.028547 (rank : 113)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	1323	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CTNA3_HUMAN
NC score	0.028240 (rank : 114)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UI47, Q5VSR2, Q6P056	Gene names	CTNNA3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

LAMA4_HUMAN
NC score	0.028172 (rank : 115)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	708	Shared Neighborhood Hits	36
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ELOA1_HUMAN
NC score	0.027511 (rank : 116)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	388	Shared Neighborhood Hits	5
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

RAPH1_HUMAN
NC score	0.023019 (rank : 117)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	593	Shared Neighborhood Hits	19
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

NEUM_MOUSE
NC score	0.022766 (rank : 118)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NOS1_HUMAN
NC score	0.021873 (rank : 119)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SIPA1_HUMAN
NC score	0.020810 (rank : 120)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	250	Shared Neighborhood Hits	18
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

NPTX1_MOUSE
NC score	0.020731 (rank : 121)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q62443	Gene names	Nptx1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NPTX1_HUMAN
NC score	0.020517 (rank : 122)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q15818, Q5FWE6	Gene names	NPTX1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

SI1L1_MOUSE
NC score	0.020410 (rank : 123)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

TAF4_HUMAN
NC score	0.020355 (rank : 124)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	687	Shared Neighborhood Hits	25
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

RNF6_HUMAN
NC score	0.020286 (rank : 125)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

MRCKB_HUMAN
NC score	0.019259 (rank : 126)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	2239	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

BRCA2_HUMAN
NC score	0.019053 (rank : 127)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

K1219_MOUSE
NC score	0.018111 (rank : 128)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

FA49A_HUMAN
NC score	0.017299 (rank : 129)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0Q0	Gene names	FAM49A
Domain Architecture	No domain graphic available
Description	Protein FAM49A.

FA49A_MOUSE
NC score	0.017295 (rank : 130)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHZ0	Gene names	Fam49a, D12Ertd553e
Domain Architecture	No domain graphic available
Description	Protein FAM49A.

DGKD_HUMAN
NC score	0.015822 (rank : 131)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

IPP1_HUMAN
NC score	0.015539 (rank : 132)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q13522, Q8TBJ2	Gene names	PPP1R1A, IPP1
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

MDC1_HUMAN
NC score	0.015534 (rank : 133)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	1446	Shared Neighborhood Hits	30
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DPOLZ_HUMAN
NC score	0.015070 (rank : 134)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

K1C16_HUMAN
NC score	0.014580 (rank : 135)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

AFTIN_MOUSE
NC score	0.014482 (rank : 136)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WT5, Q5SSE6, Q99KJ1	Gene names	Aftph, Afth
Domain Architecture	No domain graphic available
Description	Aftiphilin.

PKP4_MOUSE
NC score	0.013783 (rank : 137)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

NHS_HUMAN
NC score	0.013539 (rank : 138)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

CKAP5_HUMAN
NC score	0.012265 (rank : 139)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

CLAP2_MOUSE
NC score	0.011279 (rank : 140)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

PKP4_HUMAN
NC score	0.011188 (rank : 141)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

LAMA5_MOUSE
NC score	0.011086 (rank : 142)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	828	Shared Neighborhood Hits	25
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

DYXC1_HUMAN
NC score	0.010886 (rank : 143)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

JHD2A_HUMAN
NC score	0.010099 (rank : 144)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

ITA4_HUMAN
NC score	0.008683 (rank : 145)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P13612	Gene names	ITGA4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49d antigen).

KI13B_HUMAN
NC score	0.007438 (rank : 146)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	492	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

ARI1A_HUMAN
NC score	0.006985 (rank : 147)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	787	Shared Neighborhood Hits	10
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

PAPD5_HUMAN
NC score	0.006474 (rank : 148)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDF8, Q9NW67, Q9Y6C0	Gene names	PAPD5
Domain Architecture	No domain graphic available
Description	PAP-associated domain-containing protein 5 (EC 2.7.7.-) (Topoisomerase-related function protein 4-2) (TRF4-2).

USH2A_HUMAN
NC score	0.006166 (rank : 149)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	600	Shared Neighborhood Hits	11
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

GNAS1_MOUSE
NC score	0.005677 (rank : 150)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	651	Shared Neighborhood Hits	13
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

FANCJ_HUMAN
NC score	0.005476 (rank : 151)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

DGKZ_HUMAN
NC score	0.005266 (rank : 152)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	551	Shared Neighborhood Hits	7
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

ZN687_HUMAN
NC score	0.004791 (rank : 153)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	1244	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

EP300_HUMAN
NC score	0.003535 (rank : 154)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

KCNH2_MOUSE
NC score	0.003273 (rank : 155)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).