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Network neighborhood for query Sequence : 41_HUMAN

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41_HUMAN
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

41_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	157	Target Neighborhood Hits	157	Shared Neighborhood Hits	157
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
θ value	0 (rank : 2)	NC score	0.991839 (rank : 2)
Query Neighborhood Hits	157	Target Neighborhood Hits	184	Shared Neighborhood Hits	86
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L2_HUMAN
θ value	1.96665e-180 (rank : 3)	NC score	0.971951 (rank : 7)
Query Neighborhood Hits	157	Target Neighborhood Hits	287	Shared Neighborhood Hits	78
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	9.45368e-175 (rank : 4)	NC score	0.951764 (rank : 15)
Query Neighborhood Hits	157	Target Neighborhood Hits	459	Shared Neighborhood Hits	78
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_MOUSE
θ value	1.6163e-166 (rank : 5)	NC score	0.973519 (rank : 6)
Query Neighborhood Hits	157	Target Neighborhood Hits	250	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L3_HUMAN
θ value	1.20145e-153 (rank : 6)	NC score	0.981257 (rank : 3)
Query Neighborhood Hits	157	Target Neighborhood Hits	113	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
θ value	4.56552e-153 (rank : 7)	NC score	0.980108 (rank : 4)
Query Neighborhood Hits	157	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
θ value	1.01709e-152 (rank : 8)	NC score	0.975047 (rank : 5)
Query Neighborhood Hits	157	Target Neighborhood Hits	180	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

PTN4_HUMAN
θ value	2.47191e-82 (rank : 9)	NC score	0.676997 (rank : 32)
Query Neighborhood Hits	157	Target Neighborhood Hits	303	Shared Neighborhood Hits	52
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L5_HUMAN
θ value	1.60597e-73 (rank : 10)	NC score	0.959913 (rank : 9)
Query Neighborhood Hits	157	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FARP1_HUMAN
θ value	1.27248e-70 (rank : 11)	NC score	0.798063 (rank : 18)
Query Neighborhood Hits	157	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

E41LB_MOUSE
θ value	4.83544e-70 (rank : 12)	NC score	0.960585 (rank : 8)
Query Neighborhood Hits	157	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
θ value	1.5555e-68 (rank : 13)	NC score	0.953149 (rank : 14)
Query Neighborhood Hits	157	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41LA_HUMAN
θ value	7.71989e-68 (rank : 14)	NC score	0.953568 (rank : 12)
Query Neighborhood Hits	157	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP2_MOUSE
θ value	1.31681e-67 (rank : 15)	NC score	0.766288 (rank : 26)
Query Neighborhood Hits	157	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FRMD5_MOUSE
θ value	3.24342e-66 (rank : 16)	NC score	0.958667 (rank : 10)
Query Neighborhood Hits	157	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
θ value	3.58603e-65 (rank : 17)	NC score	0.956103 (rank : 11)
Query Neighborhood Hits	157	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FARP2_HUMAN
θ value	4.68348e-65 (rank : 18)	NC score	0.774002 (rank : 21)
Query Neighborhood Hits	157	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

E41LA_MOUSE
θ value	2.32439e-64 (rank : 19)	NC score	0.953436 (rank : 13)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTN3_HUMAN
θ value	1.11734e-58 (rank : 20)	NC score	0.647611 (rank : 36)
Query Neighborhood Hits	157	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_MOUSE
θ value	1.6774e-38 (rank : 21)	NC score	0.618461 (rank : 38)
Query Neighborhood Hits	157	Target Neighborhood Hits	155	Shared Neighborhood Hits	50
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	4.88048e-38 (rank : 22)	NC score	0.616725 (rank : 39)
Query Neighborhood Hits	157	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

EZRI_HUMAN
θ value	5.39604e-37 (rank : 23)	NC score	0.739519 (rank : 27)
Query Neighborhood Hits	157	Target Neighborhood Hits	663	Shared Neighborhood Hits	75
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	6.59618e-35 (rank : 24)	NC score	0.734834 (rank : 28)
Query Neighborhood Hits	157	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_MOUSE
θ value	4.00176e-32 (rank : 25)	NC score	0.717112 (rank : 30)
Query Neighborhood Hits	157	Target Neighborhood Hits	773	Shared Neighborhood Hits	84
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RADI_HUMAN
θ value	5.22648e-32 (rank : 26)	NC score	0.719624 (rank : 29)
Query Neighborhood Hits	157	Target Neighborhood Hits	741	Shared Neighborhood Hits	77
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

MOES_MOUSE
θ value	1.16434e-31 (rank : 27)	NC score	0.671555 (rank : 33)
Query Neighborhood Hits	157	Target Neighborhood Hits	923	Shared Neighborhood Hits	85
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	1.98606e-31 (rank : 28)	NC score	0.678725 (rank : 31)
Query Neighborhood Hits	157	Target Neighborhood Hits	892	Shared Neighborhood Hits	84
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN14_MOUSE
θ value	9.2256e-29 (rank : 29)	NC score	0.598305 (rank : 40)
Query Neighborhood Hits	157	Target Neighborhood Hits	142	Shared Neighborhood Hits	50
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

MERL_HUMAN
θ value	2.05525e-28 (rank : 30)	NC score	0.772114 (rank : 23)
Query Neighborhood Hits	157	Target Neighborhood Hits	532	Shared Neighborhood Hits	76
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	2.68423e-28 (rank : 31)	NC score	0.773054 (rank : 22)
Query Neighborhood Hits	157	Target Neighborhood Hits	524	Shared Neighborhood Hits	76
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTN14_HUMAN
θ value	2.68423e-28 (rank : 32)	NC score	0.590655 (rank : 41)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

MYLIP_HUMAN
θ value	3.50572e-28 (rank : 33)	NC score	0.840837 (rank : 17)
Query Neighborhood Hits	157	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	3.50572e-28 (rank : 34)	NC score	0.856882 (rank : 16)
Query Neighborhood Hits	157	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN13_HUMAN
θ value	4.28545e-26 (rank : 35)	NC score	0.472047 (rank : 43)
Query Neighborhood Hits	157	Target Neighborhood Hits	471	Shared Neighborhood Hits	53
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	7.30988e-26 (rank : 36)	NC score	0.481100 (rank : 42)
Query Neighborhood Hits	157	Target Neighborhood Hits	426	Shared Neighborhood Hits	52
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

FRM4B_HUMAN
θ value	1.02238e-19 (rank : 37)	NC score	0.782096 (rank : 19)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	1.02238e-19 (rank : 38)	NC score	0.779284 (rank : 20)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
θ value	8.65492e-19 (rank : 39)	NC score	0.770858 (rank : 24)
Query Neighborhood Hits	157	Target Neighborhood Hits	108	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	1.47631e-18 (rank : 40)	NC score	0.769396 (rank : 25)
Query Neighborhood Hits	157	Target Neighborhood Hits	110	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD6_MOUSE
θ value	2.28291e-11 (rank : 41)	NC score	0.667051 (rank : 34)
Query Neighborhood Hits	157	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
θ value	2.13673e-09 (rank : 42)	NC score	0.656924 (rank : 35)
Query Neighborhood Hits	157	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

TLN2_HUMAN
θ value	8.97725e-08 (rank : 43)	NC score	0.409333 (rank : 47)
Query Neighborhood Hits	157	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	1.53129e-07 (rank : 44)	NC score	0.412962 (rank : 46)
Query Neighborhood Hits	157	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
θ value	2.61198e-07 (rank : 45)	NC score	0.413364 (rank : 45)
Query Neighborhood Hits	157	Target Neighborhood Hits	213	Shared Neighborhood Hits	52
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN1_HUMAN
θ value	3.41135e-07 (rank : 46)	NC score	0.416590 (rank : 44)
Query Neighborhood Hits	157	Target Neighborhood Hits	218	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

FRMD1_HUMAN
θ value	9.92553e-07 (rank : 47)	NC score	0.640262 (rank : 37)
Query Neighborhood Hits	157	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

OXR1_MOUSE
θ value	0.00665767 (rank : 48)	NC score	0.048416 (rank : 132)
Query Neighborhood Hits	157	Target Neighborhood Hits	516	Shared Neighborhood Hits	43
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

IWS1_MOUSE
θ value	0.0113563 (rank : 49)	NC score	0.048577 (rank : 131)
Query Neighborhood Hits	157	Target Neighborhood Hits	1258	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PKHA6_MOUSE
θ value	0.0148317 (rank : 50)	NC score	0.071204 (rank : 102)
Query Neighborhood Hits	157	Target Neighborhood Hits	591	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

AKA12_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.073018 (rank : 101)
Query Neighborhood Hits	157	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

GOGA1_HUMAN
θ value	0.0330416 (rank : 52)	NC score	0.038919 (rank : 145)
Query Neighborhood Hits	157	Target Neighborhood Hits	1222	Shared Neighborhood Hits	51
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

AP3D1_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.030138 (rank : 161)
Query Neighborhood Hits	157	Target Neighborhood Hits	254	Shared Neighborhood Hits	21
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

CENPB_HUMAN
θ value	0.0563607 (rank : 54)	NC score	0.041954 (rank : 137)
Query Neighborhood Hits	157	Target Neighborhood Hits	133	Shared Neighborhood Hits	16
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

MYO7A_MOUSE
θ value	0.0563607 (rank : 55)	NC score	0.054031 (rank : 121)
Query Neighborhood Hits	157	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

BTBD7_HUMAN
θ value	0.0736092 (rank : 56)	NC score	0.038604 (rank : 146)
Query Neighborhood Hits	157	Target Neighborhood Hits	176	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

BTBD7_MOUSE
θ value	0.0736092 (rank : 57)	NC score	0.038286 (rank : 147)
Query Neighborhood Hits	157	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

NFM_HUMAN
θ value	0.125558 (rank : 58)	NC score	0.032709 (rank : 155)
Query Neighborhood Hits	157	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

POT15_HUMAN
θ value	0.125558 (rank : 59)	NC score	0.020162 (rank : 179)
Query Neighborhood Hits	157	Target Neighborhood Hits	893	Shared Neighborhood Hits	43
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

AKAP9_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.035621 (rank : 149)
Query Neighborhood Hits	157	Target Neighborhood Hits	1710	Shared Neighborhood Hits	60
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

MYO7A_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.053564 (rank : 122)
Query Neighborhood Hits	157	Target Neighborhood Hits	209	Shared Neighborhood Hits	33
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

GOGB1_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.039435 (rank : 143)
Query Neighborhood Hits	157	Target Neighborhood Hits	2297	Shared Neighborhood Hits	78
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MINT_HUMAN
θ value	0.365318 (rank : 63)	NC score	0.028836 (rank : 166)
Query Neighborhood Hits	157	Target Neighborhood Hits	1291	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NBN_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.027729 (rank : 167)
Query Neighborhood Hits	157	Target Neighborhood Hits	226	Shared Neighborhood Hits	21
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

RRBP1_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.041175 (rank : 140)
Query Neighborhood Hits	157	Target Neighborhood Hits	1650	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RHG25_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.020863 (rank : 173)
Query Neighborhood Hits	157	Target Neighborhood Hits	550	Shared Neighborhood Hits	30
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TXND2_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.029103 (rank : 165)
Query Neighborhood Hits	157	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DNL1_MOUSE
θ value	0.62314 (rank : 68)	NC score	0.017698 (rank : 187)
Query Neighborhood Hits	157	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

CD45_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.106888 (rank : 65)
Query Neighborhood Hits	157	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

DIAP2_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.016275 (rank : 190)
Query Neighborhood Hits	157	Target Neighborhood Hits	342	Shared Neighborhood Hits	20
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

MAP1B_HUMAN
θ value	0.813845 (rank : 71)	NC score	0.044486 (rank : 134)
Query Neighborhood Hits	157	Target Neighborhood Hits	903	Shared Neighborhood Hits	54
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NFM_MOUSE
θ value	0.813845 (rank : 72)	NC score	0.031313 (rank : 159)
Query Neighborhood Hits	157	Target Neighborhood Hits	1159	Shared Neighborhood Hits	65
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

CENPF_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.031996 (rank : 158)
Query Neighborhood Hits	157	Target Neighborhood Hits	1932	Shared Neighborhood Hits	63
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HPPD_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.020435 (rank : 177)
Query Neighborhood Hits	157	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).

MPP8_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.020716 (rank : 175)
Query Neighborhood Hits	157	Target Neighborhood Hits	948	Shared Neighborhood Hits	49
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYH14_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.016343 (rank : 189)
Query Neighborhood Hits	157	Target Neighborhood Hits	995	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PRP8_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.019933 (rank : 180)
Query Neighborhood Hits	157	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P2Q9, O14547, O75965	Gene names	PRPF8, PRPC8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8) (PRP8 homolog) (220 kDa U5 snRNP-specific protein) (p220).

RRBP1_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.034536 (rank : 153)
Query Neighborhood Hits	157	Target Neighborhood Hits	1306	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

ANR21_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.018199 (rank : 186)
Query Neighborhood Hits	157	Target Neighborhood Hits	864	Shared Neighborhood Hits	41
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

AR13B_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.016933 (rank : 188)
Query Neighborhood Hits	157	Target Neighborhood Hits	528	Shared Neighborhood Hits	30
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CDC5L_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.019680 (rank : 181)
Query Neighborhood Hits	157	Target Neighborhood Hits	205	Shared Neighborhood Hits	18
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

LIMA1_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.013858 (rank : 195)
Query Neighborhood Hits	157	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

CDC5L_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.019146 (rank : 183)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

GAS8_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.033671 (rank : 154)
Query Neighborhood Hits	157	Target Neighborhood Hits	819	Shared Neighborhood Hits	42
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GPR98_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.006457 (rank : 217)
Query Neighborhood Hits	157	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

NPBL_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.041002 (rank : 141)
Query Neighborhood Hits	157	Target Neighborhood Hits	1041	Shared Neighborhood Hits	49
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PAK4_MOUSE
θ value	1.81305 (rank : 87)	NC score	-0.005592 (rank : 234)
Query Neighborhood Hits	157	Target Neighborhood Hits	1098	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PRP8_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.018998 (rank : 184)
Query Neighborhood Hits	157	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PV0, Q5ND30, Q5ND31, Q7TQK2, Q8BRZ5, Q8K001	Gene names	Prpf8, Prp8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8).

BCOR_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.008906 (rank : 204)
Query Neighborhood Hits	157	Target Neighborhood Hits	521	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

MAP1B_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.041486 (rank : 139)
Query Neighborhood Hits	157	Target Neighborhood Hits	977	Shared Neighborhood Hits	59
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NCOA7_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.030945 (rank : 160)
Query Neighborhood Hits	157	Target Neighborhood Hits	160	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

NCOA7_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.025861 (rank : 170)
Query Neighborhood Hits	157	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

OGFR_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.008632 (rank : 206)
Query Neighborhood Hits	157	Target Neighborhood Hits	1582	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

FBXW7_HUMAN
θ value	3.0926 (rank : 94)	NC score	-0.000215 (rank : 230)
Query Neighborhood Hits	157	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

KBTB9_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.002046 (rank : 228)
Query Neighborhood Hits	157	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

MOV10_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.010699 (rank : 199)
Query Neighborhood Hits	157	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MYH14_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.020734 (rank : 174)
Query Neighborhood Hits	157	Target Neighborhood Hits	1225	Shared Neighborhood Hits	52
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NIN_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.029487 (rank : 163)
Query Neighborhood Hits	157	Target Neighborhood Hits	1376	Shared Neighborhood Hits	48
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RBM25_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.041766 (rank : 138)
Query Neighborhood Hits	157	Target Neighborhood Hits	682	Shared Neighborhood Hits	51
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SIA7A_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.008225 (rank : 210)
Query Neighborhood Hits	157	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

TXND2_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.039369 (rank : 144)
Query Neighborhood Hits	157	Target Neighborhood Hits	828	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP43_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.004057 (rank : 222)
Query Neighborhood Hits	157	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

AKAP8_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.009793 (rank : 202)
Query Neighborhood Hits	157	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

CD008_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.013589 (rank : 196)
Query Neighborhood Hits	157	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CENPB_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.035328 (rank : 150)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

DNMT1_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.034682 (rank : 152)
Query Neighborhood Hits	157	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

GOGA4_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.032317 (rank : 157)
Query Neighborhood Hits	157	Target Neighborhood Hits	1939	Shared Neighborhood Hits	70
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HDAC5_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.008641 (rank : 205)
Query Neighborhood Hits	157	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

HSH2D_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.007047 (rank : 214)
Query Neighborhood Hits	157	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

K0555_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.032569 (rank : 156)
Query Neighborhood Hits	157	Target Neighborhood Hits	880	Shared Neighborhood Hits	49
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

NEBL_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.023241 (rank : 171)
Query Neighborhood Hits	157	Target Neighborhood Hits	457	Shared Neighborhood Hits	26
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

PCLO_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.018643 (rank : 185)
Query Neighborhood Hits	157	Target Neighborhood Hits	2046	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.020587 (rank : 176)
Query Neighborhood Hits	157	Target Neighborhood Hits	2275	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZN394_MOUSE
θ value	4.03905 (rank : 114)	NC score	-0.005577 (rank : 233)
Query Neighborhood Hits	157	Target Neighborhood Hits	738	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1D9, Q3U4Z1, Q9CYV9, Q9CZG8	Gene names	Znf394, Zfp94, Zfp99
Domain Architecture
Description	Zinc finger protein 394 (Zinc finger protein 94) (Zfp-94).

ACRBP_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.015874 (rank : 191)
Query Neighborhood Hits	157	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V140, Q62253, Q62254, Q8C621, Q91VQ1	Gene names	Acrbp
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32).

GCC2_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.030082 (rank : 162)
Query Neighborhood Hits	157	Target Neighborhood Hits	1619	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GNL3_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.008413 (rank : 208)
Query Neighborhood Hits	157	Target Neighborhood Hits	99	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

IF4G1_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.013997 (rank : 194)
Query Neighborhood Hits	157	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

LRMP_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.021896 (rank : 172)
Query Neighborhood Hits	157	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

MELPH_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.006696 (rank : 215)
Query Neighborhood Hits	157	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

RBM19_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.003497 (rank : 226)
Query Neighborhood Hits	157	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

BBX_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.008533 (rank : 207)
Query Neighborhood Hits	157	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

CCHCR_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.026022 (rank : 169)
Query Neighborhood Hits	157	Target Neighborhood Hits	932	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CHD5_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.007965 (rank : 211)
Query Neighborhood Hits	157	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CU067_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.020373 (rank : 178)
Query Neighborhood Hits	157	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P58512	Gene names	C21orf67
Domain Architecture	No domain graphic available
Description	Protein C21orf67.

CUTL2_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.026311 (rank : 168)
Query Neighborhood Hits	157	Target Neighborhood Hits	906	Shared Neighborhood Hits	46
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DIDO1_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.007573 (rank : 212)
Query Neighborhood Hits	157	Target Neighborhood Hits	960	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GOGA4_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.039563 (rank : 142)
Query Neighborhood Hits	157	Target Neighborhood Hits	2034	Shared Neighborhood Hits	70
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HPPD_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.015506 (rank : 192)
Query Neighborhood Hits	157	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	P49429, P97322, Q3UEQ0, Q91WV9	Gene names	Hpd
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (4- hydroxyphenylpyruvic acid oxidase) (HPPDase) (F protein) (F Alloantigen).

KBTB9_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.001456 (rank : 229)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KCD17_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.003103 (rank : 227)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

LEPR_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.013075 (rank : 197)
Query Neighborhood Hits	157	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

NIPBL_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.042423 (rank : 136)
Query Neighborhood Hits	157	Target Neighborhood Hits	1311	Shared Neighborhood Hits	67
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NSBP1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.034773 (rank : 151)
Query Neighborhood Hits	157	Target Neighborhood Hits	681	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PLCB1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.015317 (rank : 193)
Query Neighborhood Hits	157	Target Neighborhood Hits	614	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

R3HD2_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.004487 (rank : 220)
Query Neighborhood Hits	157	Target Neighborhood Hits	397	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

TBP_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.006513 (rank : 216)
Query Neighborhood Hits	157	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P20226, Q16845, Q9UC02	Gene names	TBP, TF2D, TFIID
Domain Architecture
Description	TATA-box-binding protein (TATA-box factor) (TATA-binding factor) (TATA sequence-binding protein) (Transcription initiation factor TFIID TBP subunit).

TCF8_MOUSE
θ value	6.88961 (rank : 138)	NC score	-0.003045 (rank : 231)
Query Neighborhood Hits	157	Target Neighborhood Hits	1067	Shared Neighborhood Hits	27
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

UT14A_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.019412 (rank : 182)
Query Neighborhood Hits	157	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

ASXL1_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.010119 (rank : 200)
Query Neighborhood Hits	157	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CCD96_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.048156 (rank : 133)
Query Neighborhood Hits	157	Target Neighborhood Hits	595	Shared Neighborhood Hits	48
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CK5P2_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.042596 (rank : 135)
Query Neighborhood Hits	157	Target Neighborhood Hits	1433	Shared Neighborhood Hits	56
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

DTX2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.003612 (rank : 225)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

FMNL_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.012997 (rank : 198)
Query Neighborhood Hits	157	Target Neighborhood Hits	428	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GOGA3_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.029107 (rank : 164)
Query Neighborhood Hits	157	Target Neighborhood Hits	1317	Shared Neighborhood Hits	46
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

MAP1A_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.054857 (rank : 119)
Query Neighborhood Hits	157	Target Neighborhood Hits	1626	Shared Neighborhood Hits	70
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NOP5_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.007330 (rank : 213)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

PARP2_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.003776 (rank : 224)
Query Neighborhood Hits	157	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PRDM2_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.004180 (rank : 221)
Query Neighborhood Hits	157	Target Neighborhood Hits	1135	Shared Neighborhood Hits	31
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SMC2_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.035755 (rank : 148)
Query Neighborhood Hits	157	Target Neighborhood Hits	1405	Shared Neighborhood Hits	62
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TRPS1_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.008271 (rank : 209)
Query Neighborhood Hits	157	Target Neighborhood Hits	539	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

TRPS1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.009895 (rank : 201)
Query Neighborhood Hits	157	Target Neighborhood Hits	609	Shared Neighborhood Hits	13
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

TSH1_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.003997 (rank : 223)
Query Neighborhood Hits	157	Target Neighborhood Hits	675	Shared Neighborhood Hits	15
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

UCRH_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.009079 (rank : 203)
Query Neighborhood Hits	157	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P07919, Q6LDB8, Q9BQ91	Gene names	UQCRH
Domain Architecture
Description	Ubiquinol-cytochrome c reductase complex 11 kDa protein, mitochondrial precursor (EC 1.10.2.2) (Mitochondrial hinge protein) (Cytochrome c1 nonheme 11 kDa protein) (Complex III subunit VIII).

UE1D1_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.005398 (rank : 218)
Query Neighborhood Hits	157	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

ZN406_MOUSE
θ value	8.99809 (rank : 156)	NC score	-0.004787 (rank : 232)
Query Neighborhood Hits	157	Target Neighborhood Hits	800	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

ZN750_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.004708 (rank : 219)
Query Neighborhood Hits	157	Target Neighborhood Hits	346	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ARHG4_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.051000 (rank : 126)
Query Neighborhood Hits	157	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CA106_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.082082 (rank : 95)
Query Neighborhood Hits	157	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.080833 (rank : 98)
Query Neighborhood Hits	157	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CCD96_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.050789 (rank : 127)
Query Neighborhood Hits	157	Target Neighborhood Hits	704	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CD45_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.100095 (rank : 81)
Query Neighborhood Hits	157	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CT2NL_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.050201 (rank : 129)
Query Neighborhood Hits	157	Target Neighborhood Hits	1059	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FGD1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.059928 (rank : 113)
Query Neighborhood Hits	157	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.058116 (rank : 116)
Query Neighborhood Hits	157	Target Neighborhood Hits	387	Shared Neighborhood Hits	13
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.050013 (rank : 130)
Query Neighborhood Hits	157	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.054378 (rank : 120)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.052602 (rank : 123)
Query Neighborhood Hits	157	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.051643 (rank : 125)
Query Neighborhood Hits	157	Target Neighborhood Hits	257	Shared Neighborhood Hits	7
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.059688 (rank : 115)
Query Neighborhood Hits	157	Target Neighborhood Hits	219	Shared Neighborhood Hits	7
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.059887 (rank : 114)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.065538 (rank : 105)
Query Neighborhood Hits	157	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.061056 (rank : 111)
Query Neighborhood Hits	157	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.063186 (rank : 108)
Query Neighborhood Hits	157	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.062454 (rank : 109)
Query Neighborhood Hits	157	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.060160 (rank : 112)
Query Neighborhood Hits	157	Target Neighborhood Hits	809	Shared Neighborhood Hits	47
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.056623 (rank : 117)
Query Neighborhood Hits	157	Target Neighborhood Hits	959	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.062410 (rank : 110)
Query Neighborhood Hits	157	Target Neighborhood Hits	1016	Shared Neighborhood Hits	56
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.083885 (rank : 92)
Query Neighborhood Hits	157	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.077874 (rank : 100)
Query Neighborhood Hits	157	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NASP_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.055513 (rank : 118)
Query Neighborhood Hits	157	Target Neighborhood Hits	709	Shared Neighborhood Hits	46
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PKHA5_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.051932 (rank : 124)
Query Neighborhood Hits	157	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.050725 (rank : 128)
Query Neighborhood Hits	157	Target Neighborhood Hits	556	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.102439 (rank : 78)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.102447 (rank : 77)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.108993 (rank : 61)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.109060 (rank : 59)
Query Neighborhood Hits	157	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.117755 (rank : 50)
Query Neighborhood Hits	157	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.114157 (rank : 53)
Query Neighborhood Hits	157	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.117700 (rank : 52)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.118091 (rank : 49)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.111012 (rank : 56)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.109014 (rank : 60)
Query Neighborhood Hits	157	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.104450 (rank : 71)
Query Neighborhood Hits	157	Target Neighborhood Hits	646	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.102805 (rank : 73)
Query Neighborhood Hits	157	Target Neighborhood Hits	726	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.117749 (rank : 51)
Query Neighborhood Hits	157	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.119030 (rank : 48)
Query Neighborhood Hits	157	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.102456 (rank : 76)
Query Neighborhood Hits	157	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.102457 (rank : 75)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.108919 (rank : 62)
Query Neighborhood Hits	157	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.108658 (rank : 63)
Query Neighborhood Hits	157	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.109194 (rank : 58)
Query Neighborhood Hits	157	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.110344 (rank : 57)
Query Neighborhood Hits	157	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.113826 (rank : 54)
Query Neighborhood Hits	157	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.113468 (rank : 55)
Query Neighborhood Hits	157	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.106979 (rank : 64)
Query Neighborhood Hits	157	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.106733 (rank : 68)
Query Neighborhood Hits	157	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.095748 (rank : 84)
Query Neighborhood Hits	157	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.095602 (rank : 85)
Query Neighborhood Hits	157	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.100040 (rank : 82)
Query Neighborhood Hits	157	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.066351 (rank : 104)
Query Neighborhood Hits	157	Target Neighborhood Hits	485	Shared Neighborhood Hits	15
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.063832 (rank : 107)
Query Neighborhood Hits	157	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.096027 (rank : 83)
Query Neighborhood Hits	157	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.095539 (rank : 86)
Query Neighborhood Hits	157	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.064631 (rank : 106)
Query Neighborhood Hits	157	Target Neighborhood Hits	489	Shared Neighborhood Hits	10
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.085430 (rank : 91)
Query Neighborhood Hits	157	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.085693 (rank : 90)
Query Neighborhood Hits	157	Target Neighborhood Hits	260	Shared Neighborhood Hits	17
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.102134 (rank : 79)
Query Neighborhood Hits	157	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.102561 (rank : 74)
Query Neighborhood Hits	157	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.085856 (rank : 88)
Query Neighborhood Hits	157	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.086571 (rank : 87)
Query Neighborhood Hits	157	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.080816 (rank : 99)
Query Neighborhood Hits	157	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.081202 (rank : 96)
Query Neighborhood Hits	157	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.106782 (rank : 67)
Query Neighborhood Hits	157	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.106184 (rank : 69)
Query Neighborhood Hits	157	Target Neighborhood Hits	240	Shared Neighborhood Hits	15
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.106848 (rank : 66)
Query Neighborhood Hits	157	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.104434 (rank : 72)
Query Neighborhood Hits	157	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.104736 (rank : 70)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.067540 (rank : 103)
Query Neighborhood Hits	157	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.083119 (rank : 93)
Query Neighborhood Hits	157	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.083053 (rank : 94)
Query Neighborhood Hits	157	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.080900 (rank : 97)
Query Neighborhood Hits	157	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.101606 (rank : 80)
Query Neighborhood Hits	157	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.085811 (rank : 89)
Query Neighborhood Hits	157	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

Hits sorted by NC score

41_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	157	Target Neighborhood Hits	157	Shared Neighborhood Hits	157
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
NC score	0.991839 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	157	Target Neighborhood Hits	184	Shared Neighborhood Hits	86
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L3_HUMAN
NC score	0.981257 (rank : 3)	θ value	1.20145e-153 (rank : 6)
Query Neighborhood Hits	157	Target Neighborhood Hits	113	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
NC score	0.980108 (rank : 4)	θ value	4.56552e-153 (rank : 7)
Query Neighborhood Hits	157	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.975047 (rank : 5)	θ value	1.01709e-152 (rank : 8)
Query Neighborhood Hits	157	Target Neighborhood Hits	180	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_MOUSE
NC score	0.973519 (rank : 6)	θ value	1.6163e-166 (rank : 5)
Query Neighborhood Hits	157	Target Neighborhood Hits	250	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.971951 (rank : 7)	θ value	1.96665e-180 (rank : 3)
Query Neighborhood Hits	157	Target Neighborhood Hits	287	Shared Neighborhood Hits	78
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41LB_MOUSE
NC score	0.960585 (rank : 8)	θ value	4.83544e-70 (rank : 12)
Query Neighborhood Hits	157	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L5_HUMAN
NC score	0.959913 (rank : 9)	θ value	1.60597e-73 (rank : 10)
Query Neighborhood Hits	157	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRMD5_MOUSE
NC score	0.958667 (rank : 10)	θ value	3.24342e-66 (rank : 16)
Query Neighborhood Hits	157	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.956103 (rank : 11)	θ value	3.58603e-65 (rank : 17)
Query Neighborhood Hits	157	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LA_HUMAN
NC score	0.953568 (rank : 12)	θ value	7.71989e-68 (rank : 14)
Query Neighborhood Hits	157	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.953436 (rank : 13)	θ value	2.32439e-64 (rank : 19)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_HUMAN
NC score	0.953149 (rank : 14)	θ value	1.5555e-68 (rank : 13)
Query Neighborhood Hits	157	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L2_MOUSE
NC score	0.951764 (rank : 15)	θ value	9.45368e-175 (rank : 4)
Query Neighborhood Hits	157	Target Neighborhood Hits	459	Shared Neighborhood Hits	78
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.856882 (rank : 16)	θ value	3.50572e-28 (rank : 34)
Query Neighborhood Hits	157	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.840837 (rank : 17)	θ value	3.50572e-28 (rank : 33)
Query Neighborhood Hits	157	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FARP1_HUMAN
NC score	0.798063 (rank : 18)	θ value	1.27248e-70 (rank : 11)
Query Neighborhood Hits	157	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRM4B_HUMAN
NC score	0.782096 (rank : 19)	θ value	1.02238e-19 (rank : 37)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.779284 (rank : 20)	θ value	1.02238e-19 (rank : 38)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FARP2_HUMAN
NC score	0.774002 (rank : 21)	θ value	4.68348e-65 (rank : 18)
Query Neighborhood Hits	157	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MERL_MOUSE
NC score	0.773054 (rank : 22)	θ value	2.68423e-28 (rank : 31)
Query Neighborhood Hits	157	Target Neighborhood Hits	524	Shared Neighborhood Hits	76
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.772114 (rank : 23)	θ value	2.05525e-28 (rank : 30)
Query Neighborhood Hits	157	Target Neighborhood Hits	532	Shared Neighborhood Hits	76
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FRM4A_MOUSE
NC score	0.770858 (rank : 24)	θ value	8.65492e-19 (rank : 39)
Query Neighborhood Hits	157	Target Neighborhood Hits	108	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.769396 (rank : 25)	θ value	1.47631e-18 (rank : 40)
Query Neighborhood Hits	157	Target Neighborhood Hits	110	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FARP2_MOUSE
NC score	0.766288 (rank : 26)	θ value	1.31681e-67 (rank : 15)
Query Neighborhood Hits	157	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.739519 (rank : 27)	θ value	5.39604e-37 (rank : 23)
Query Neighborhood Hits	157	Target Neighborhood Hits	663	Shared Neighborhood Hits	75
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.734834 (rank : 28)	θ value	6.59618e-35 (rank : 24)
Query Neighborhood Hits	157	Target Neighborhood Hits	693	Shared Neighborhood Hits	75
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.719624 (rank : 29)	θ value	5.22648e-32 (rank : 26)
Query Neighborhood Hits	157	Target Neighborhood Hits	741	Shared Neighborhood Hits	77
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.717112 (rank : 30)	θ value	4.00176e-32 (rank : 25)
Query Neighborhood Hits	157	Target Neighborhood Hits	773	Shared Neighborhood Hits	84
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_HUMAN
NC score	0.678725 (rank : 31)	θ value	1.98606e-31 (rank : 28)
Query Neighborhood Hits	157	Target Neighborhood Hits	892	Shared Neighborhood Hits	84
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN4_HUMAN
NC score	0.676997 (rank : 32)	θ value	2.47191e-82 (rank : 9)
Query Neighborhood Hits	157	Target Neighborhood Hits	303	Shared Neighborhood Hits	52
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MOES_MOUSE
NC score	0.671555 (rank : 33)	θ value	1.16434e-31 (rank : 27)
Query Neighborhood Hits	157	Target Neighborhood Hits	923	Shared Neighborhood Hits	85
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD6_MOUSE
NC score	0.667051 (rank : 34)	θ value	2.28291e-11 (rank : 41)
Query Neighborhood Hits	157	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.656924 (rank : 35)	θ value	2.13673e-09 (rank : 42)
Query Neighborhood Hits	157	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN3_HUMAN
NC score	0.647611 (rank : 36)	θ value	1.11734e-58 (rank : 20)
Query Neighborhood Hits	157	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FRMD1_HUMAN
NC score	0.640262 (rank : 37)	θ value	9.92553e-07 (rank : 47)
Query Neighborhood Hits	157	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PTN21_MOUSE
NC score	0.618461 (rank : 38)	θ value	1.6774e-38 (rank : 21)
Query Neighborhood Hits	157	Target Neighborhood Hits	155	Shared Neighborhood Hits	50
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.616725 (rank : 39)	θ value	4.88048e-38 (rank : 22)
Query Neighborhood Hits	157	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.598305 (rank : 40)	θ value	9.2256e-29 (rank : 29)
Query Neighborhood Hits	157	Target Neighborhood Hits	142	Shared Neighborhood Hits	50
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.590655 (rank : 41)	θ value	2.68423e-28 (rank : 32)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.481100 (rank : 42)	θ value	7.30988e-26 (rank : 36)
Query Neighborhood Hits	157	Target Neighborhood Hits	426	Shared Neighborhood Hits	52
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.472047 (rank : 43)	θ value	4.28545e-26 (rank : 35)
Query Neighborhood Hits	157	Target Neighborhood Hits	471	Shared Neighborhood Hits	53
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TLN1_HUMAN
NC score	0.416590 (rank : 44)	θ value	3.41135e-07 (rank : 46)
Query Neighborhood Hits	157	Target Neighborhood Hits	218	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.413364 (rank : 45)	θ value	2.61198e-07 (rank : 45)
Query Neighborhood Hits	157	Target Neighborhood Hits	213	Shared Neighborhood Hits	52
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.412962 (rank : 46)	θ value	1.53129e-07 (rank : 44)
Query Neighborhood Hits	157	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.409333 (rank : 47)	θ value	8.97725e-08 (rank : 43)
Query Neighborhood Hits	157	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

PTN2_MOUSE
NC score	0.119030 (rank : 48)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	157	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.118091 (rank : 49)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN18_HUMAN
NC score	0.117755 (rank : 50)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	157	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN2_HUMAN
NC score	0.117749 (rank : 51)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	157	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN1_HUMAN
NC score	0.117700 (rank : 52)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_MOUSE
NC score	0.114157 (rank : 53)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	157	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.113826 (rank : 54)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	157	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.113468 (rank : 55)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	157	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.111012 (rank : 56)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.110344 (rank : 57)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	157	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.109194 (rank : 58)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	157	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_MOUSE
NC score	0.109060 (rank : 59)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	157	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_MOUSE
NC score	0.109014 (rank : 60)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	157	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN12_HUMAN
NC score	0.108993 (rank : 61)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN6_HUMAN
NC score	0.108919 (rank : 62)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	157	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.108658 (rank : 63)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	157	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPR2_HUMAN
NC score	0.106979 (rank : 64)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	157	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

CD45_MOUSE
NC score	0.106888 (rank : 65)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	157	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRO_HUMAN
NC score	0.106848 (rank : 66)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	157	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRN_HUMAN
NC score	0.106782 (rank : 67)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	157	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPR2_MOUSE
NC score	0.106733 (rank : 68)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	157	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_MOUSE
NC score	0.106184 (rank : 69)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	157	Target Neighborhood Hits	240	Shared Neighborhood Hits	15
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_MOUSE
NC score	0.104736 (rank : 70)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTN23_HUMAN
NC score	0.104450 (rank : 71)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	157	Target Neighborhood Hits	646	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRR_HUMAN
NC score	0.104434 (rank : 72)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	157	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN23_MOUSE
NC score	0.102805 (rank : 73)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	157	Target Neighborhood Hits	726	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPRJ_MOUSE
NC score	0.102561 (rank : 74)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	157	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN5_MOUSE
NC score	0.102457 (rank : 75)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.102456 (rank : 76)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	157	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_MOUSE
NC score	0.102447 (rank : 77)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.102439 (rank : 78)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRJ_HUMAN
NC score	0.102134 (rank : 79)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	157	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRV_MOUSE
NC score	0.101606 (rank : 80)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	157	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

CD45_HUMAN
NC score	0.100095 (rank : 81)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	157	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRB_HUMAN
NC score	0.100040 (rank : 82)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	157	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRE_HUMAN
NC score	0.096027 (rank : 83)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	157	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.095748 (rank : 84)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	157	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.095602 (rank : 85)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	157	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.095539 (rank : 86)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	157	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRK_MOUSE
NC score	0.086571 (rank : 87)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	157	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_HUMAN
NC score	0.085856 (rank : 88)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	157	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRZ_HUMAN
NC score	0.085811 (rank : 89)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	157	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_MOUSE
NC score	0.085693 (rank : 90)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	157	Target Neighborhood Hits	260	Shared Neighborhood Hits	17
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.085430 (rank : 91)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	157	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

KRIT1_HUMAN
NC score	0.083885 (rank : 92)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	157	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTPRT_HUMAN
NC score	0.083119 (rank : 93)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	157	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.083053 (rank : 94)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	157	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

CA106_HUMAN
NC score	0.082082 (rank : 95)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	157	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

PTPRM_MOUSE
NC score	0.081202 (rank : 96)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	157	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.080900 (rank : 97)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	157	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CA106_MOUSE
NC score	0.080833 (rank : 98)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	157	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PTPRM_HUMAN
NC score	0.080816 (rank : 99)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	157	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KRIT1_MOUSE
NC score	0.077874 (rank : 100)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	157	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

AKA12_HUMAN
NC score	0.073018 (rank : 101)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	157	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

PKHA6_MOUSE
NC score	0.071204 (rank : 102)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	157	Target Neighborhood Hits	591	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTPRS_HUMAN
NC score	0.067540 (rank : 103)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	157	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.066351 (rank : 104)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	157	Target Neighborhood Hits	485	Shared Neighborhood Hits	15
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FGD5_HUMAN
NC score	0.065538 (rank : 105)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	157	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

PTPRF_HUMAN
NC score	0.064631 (rank : 106)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	157	Target Neighborhood Hits	489	Shared Neighborhood Hits	10
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.063832 (rank : 107)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	157	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FGD6_HUMAN
NC score	0.063186 (rank : 108)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	157	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.062454 (rank : 109)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	157	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1_HUMAN
NC score	0.062410 (rank : 110)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	157	Target Neighborhood Hits	1016	Shared Neighborhood Hits	56
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

FGD5_MOUSE
NC score	0.061056 (rank : 111)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	157	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

HIP1R_HUMAN
NC score	0.060160 (rank : 112)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	157	Target Neighborhood Hits	809	Shared Neighborhood Hits	47
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

FGD1_HUMAN
NC score	0.059928 (rank : 113)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	157	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD4_MOUSE
NC score	0.059887 (rank : 114)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD4_HUMAN
NC score	0.059688 (rank : 115)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	157	Target Neighborhood Hits	219	Shared Neighborhood Hits	7
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD1_MOUSE
NC score	0.058116 (rank : 116)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	157	Target Neighborhood Hits	387	Shared Neighborhood Hits	13
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HIP1R_MOUSE
NC score	0.056623 (rank : 117)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	157	Target Neighborhood Hits	959	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

NASP_HUMAN
NC score	0.055513 (rank : 118)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	157	Target Neighborhood Hits	709	Shared Neighborhood Hits	46
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

MAP1A_HUMAN
NC score	0.054857 (rank : 119)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	157	Target Neighborhood Hits	1626	Shared Neighborhood Hits	70
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

FGD2_MOUSE
NC score	0.054378 (rank : 120)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

MYO7A_MOUSE
NC score	0.054031 (rank : 121)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	157	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.053564 (rank : 122)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	157	Target Neighborhood Hits	209	Shared Neighborhood Hits	33
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

FGD3_HUMAN
NC score	0.052602 (rank : 123)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	157	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

PKHA5_HUMAN
NC score	0.051932 (rank : 124)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	157	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

FGD3_MOUSE
NC score	0.051643 (rank : 125)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	157	Target Neighborhood Hits	257	Shared Neighborhood Hits	7
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

ARHG4_MOUSE
NC score	0.051000 (rank : 126)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	157	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CCD96_MOUSE
NC score	0.050789 (rank : 127)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	157	Target Neighborhood Hits	704	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

PKHA6_HUMAN
NC score	0.050725 (rank : 128)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	157	Target Neighborhood Hits	556	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CT2NL_HUMAN
NC score	0.050201 (rank : 129)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	157	Target Neighborhood Hits	1059	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FGD2_HUMAN
NC score	0.050013 (rank : 130)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	157	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

IWS1_MOUSE
NC score	0.048577 (rank : 131)	θ value	0.0113563 (rank : 49)
Query Neighborhood Hits	157	Target Neighborhood Hits	1258	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

OXR1_MOUSE
NC score	0.048416 (rank : 132)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	157	Target Neighborhood Hits	516	Shared Neighborhood Hits	43
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

CCD96_HUMAN
NC score	0.048156 (rank : 133)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	157	Target Neighborhood Hits	595	Shared Neighborhood Hits	48
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

MAP1B_HUMAN
NC score	0.044486 (rank : 134)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	157	Target Neighborhood Hits	903	Shared Neighborhood Hits	54
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CK5P2_HUMAN
NC score	0.042596 (rank : 135)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	157	Target Neighborhood Hits	1433	Shared Neighborhood Hits	56
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

NIPBL_HUMAN
NC score	0.042423 (rank : 136)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	157	Target Neighborhood Hits	1311	Shared Neighborhood Hits	67
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CENPB_HUMAN
NC score	0.041954 (rank : 137)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	157	Target Neighborhood Hits	133	Shared Neighborhood Hits	16
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

RBM25_HUMAN
NC score	0.041766 (rank : 138)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	157	Target Neighborhood Hits	682	Shared Neighborhood Hits	51
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

MAP1B_MOUSE
NC score	0.041486 (rank : 139)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	157	Target Neighborhood Hits	977	Shared Neighborhood Hits	59
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RRBP1_MOUSE
NC score	0.041175 (rank : 140)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	157	Target Neighborhood Hits	1650	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NPBL_MOUSE
NC score	0.041002 (rank : 141)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	157	Target Neighborhood Hits	1041	Shared Neighborhood Hits	49
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

GOGA4_HUMAN
NC score	0.039563 (rank : 142)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	157	Target Neighborhood Hits	2034	Shared Neighborhood Hits	70
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGB1_HUMAN
NC score	0.039435 (rank : 143)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	157	Target Neighborhood Hits	2297	Shared Neighborhood Hits	78
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TXND2_MOUSE
NC score	0.039369 (rank : 144)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	157	Target Neighborhood Hits	828	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

GOGA1_HUMAN
NC score	0.038919 (rank : 145)	θ value	0.0330416 (rank : 52)
Query Neighborhood Hits	157	Target Neighborhood Hits	1222	Shared Neighborhood Hits	51
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

BTBD7_HUMAN
NC score	0.038604 (rank : 146)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	157	Target Neighborhood Hits	176	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

BTBD7_MOUSE
NC score	0.038286 (rank : 147)	θ value	0.0736092 (rank : 57)
Query Neighborhood Hits	157	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

SMC2_HUMAN
NC score	0.035755 (rank : 148)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	157	Target Neighborhood Hits	1405	Shared Neighborhood Hits	62
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

AKAP9_HUMAN
NC score	0.035621 (rank : 149)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	157	Target Neighborhood Hits	1710	Shared Neighborhood Hits	60
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CENPB_MOUSE
NC score	0.035328 (rank : 150)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

NSBP1_MOUSE
NC score	0.034773 (rank : 151)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	157	Target Neighborhood Hits	681	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

DNMT1_HUMAN
NC score	0.034682 (rank : 152)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	157	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

RRBP1_HUMAN
NC score	0.034536 (rank : 153)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	157	Target Neighborhood Hits	1306	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

GAS8_HUMAN
NC score	0.033671 (rank : 154)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	157	Target Neighborhood Hits	819	Shared Neighborhood Hits	42
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

NFM_HUMAN
NC score	0.032709 (rank : 155)	θ value	0.125558 (rank : 58)
Query Neighborhood Hits	157	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

K0555_HUMAN
NC score	0.032569 (rank : 156)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	157	Target Neighborhood Hits	880	Shared Neighborhood Hits	49
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

GOGA4_MOUSE
NC score	0.032317 (rank : 157)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	157	Target Neighborhood Hits	1939	Shared Neighborhood Hits	70
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CENPF_HUMAN
NC score	0.031996 (rank : 158)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	157	Target Neighborhood Hits	1932	Shared Neighborhood Hits	63
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NFM_MOUSE
NC score	0.031313 (rank : 159)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	157	Target Neighborhood Hits	1159	Shared Neighborhood Hits	65
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NCOA7_HUMAN
NC score	0.030945 (rank : 160)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	157	Target Neighborhood Hits	160	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

AP3D1_HUMAN
NC score	0.030138 (rank : 161)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	157	Target Neighborhood Hits	254	Shared Neighborhood Hits	21
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

GCC2_MOUSE
NC score	0.030082 (rank : 162)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	157	Target Neighborhood Hits	1619	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

NIN_MOUSE
NC score	0.029487 (rank : 163)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	157	Target Neighborhood Hits	1376	Shared Neighborhood Hits	48
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

GOGA3_HUMAN
NC score	0.029107 (rank : 164)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	157	Target Neighborhood Hits	1317	Shared Neighborhood Hits	46
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

TXND2_HUMAN
NC score	0.029103 (rank : 165)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	157	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MINT_HUMAN
NC score	0.028836 (rank : 166)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	157	Target Neighborhood Hits	1291	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NBN_HUMAN
NC score	0.027729 (rank : 167)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	157	Target Neighborhood Hits	226	Shared Neighborhood Hits	21
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

CUTL2_HUMAN
NC score	0.026311 (rank : 168)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	157	Target Neighborhood Hits	906	Shared Neighborhood Hits	46
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CCHCR_MOUSE
NC score	0.026022 (rank : 169)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	157	Target Neighborhood Hits	932	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

NCOA7_MOUSE
NC score	0.025861 (rank : 170)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	157	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

NEBL_HUMAN
NC score	0.023241 (rank : 171)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	157	Target Neighborhood Hits	457	Shared Neighborhood Hits	26
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

LRMP_HUMAN
NC score	0.021896 (rank : 172)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	157	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

RHG25_HUMAN
NC score	0.020863 (rank : 173)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	157	Target Neighborhood Hits	550	Shared Neighborhood Hits	30
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MYH14_MOUSE
NC score	0.020734 (rank : 174)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	157	Target Neighborhood Hits	1225	Shared Neighborhood Hits	52
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MPP8_HUMAN
NC score	0.020716 (rank : 175)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	157	Target Neighborhood Hits	948	Shared Neighborhood Hits	49
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

PCLO_MOUSE
NC score	0.020587 (rank : 176)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	157	Target Neighborhood Hits	2275	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

HPPD_HUMAN
NC score	0.020435 (rank : 177)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	157	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P32754, Q13234	Gene names	HPD, PPD
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid oxidase).

CU067_HUMAN
NC score	0.020373 (rank : 178)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	157	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P58512	Gene names	C21orf67
Domain Architecture	No domain graphic available
Description	Protein C21orf67.

POT15_HUMAN
NC score	0.020162 (rank : 179)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	157	Target Neighborhood Hits	893	Shared Neighborhood Hits	43
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PRP8_HUMAN
NC score	0.019933 (rank : 180)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	157	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P2Q9, O14547, O75965	Gene names	PRPF8, PRPC8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8) (PRP8 homolog) (220 kDa U5 snRNP-specific protein) (p220).

CDC5L_MOUSE
NC score	0.019680 (rank : 181)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	157	Target Neighborhood Hits	205	Shared Neighborhood Hits	18
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

UT14A_HUMAN
NC score	0.019412 (rank : 182)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	157	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

CDC5L_HUMAN
NC score	0.019146 (rank : 183)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

PRP8_MOUSE
NC score	0.018998 (rank : 184)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	157	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PV0, Q5ND30, Q5ND31, Q7TQK2, Q8BRZ5, Q8K001	Gene names	Prpf8, Prp8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8).

PCLO_HUMAN
NC score	0.018643 (rank : 185)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	157	Target Neighborhood Hits	2046	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ANR21_HUMAN
NC score	0.018199 (rank : 186)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	157	Target Neighborhood Hits	864	Shared Neighborhood Hits	41
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

DNL1_MOUSE
NC score	0.017698 (rank : 187)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	157	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

AR13B_HUMAN
NC score	0.016933 (rank : 188)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	157	Target Neighborhood Hits	528	Shared Neighborhood Hits	30
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

MYH14_HUMAN
NC score	0.016343 (rank : 189)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	157	Target Neighborhood Hits	995	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

DIAP2_HUMAN
NC score	0.016275 (rank : 190)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	157	Target Neighborhood Hits	342	Shared Neighborhood Hits	20
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

ACRBP_MOUSE
NC score	0.015874 (rank : 191)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	157	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V140, Q62253, Q62254, Q8C621, Q91VQ1	Gene names	Acrbp
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32).

HPPD_MOUSE
NC score	0.015506 (rank : 192)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	157	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	P49429, P97322, Q3UEQ0, Q91WV9	Gene names	Hpd
Domain Architecture
Description	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (4- hydroxyphenylpyruvic acid oxidase) (HPPDase) (F protein) (F Alloantigen).

PLCB1_HUMAN
NC score	0.015317 (rank : 193)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	157	Target Neighborhood Hits	614	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

IF4G1_MOUSE
NC score	0.013997 (rank : 194)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	157	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

LIMA1_HUMAN
NC score	0.013858 (rank : 195)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	157	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

CD008_HUMAN
NC score	0.013589 (rank : 196)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	157	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

LEPR_HUMAN
NC score	0.013075 (rank : 197)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	157	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

FMNL_MOUSE
NC score	0.012997 (rank : 198)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	157	Target Neighborhood Hits	428	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

MOV10_HUMAN
NC score	0.010699 (rank : 199)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	157	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

ASXL1_MOUSE
NC score	0.010119 (rank : 200)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	157	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TRPS1_MOUSE
NC score	0.009895 (rank : 201)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	157	Target Neighborhood Hits	609	Shared Neighborhood Hits	13
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

AKAP8_HUMAN
NC score	0.009793 (rank : 202)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	157	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

UCRH_HUMAN
NC score	0.009079 (rank : 203)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	157	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P07919, Q6LDB8, Q9BQ91	Gene names	UQCRH
Domain Architecture
Description	Ubiquinol-cytochrome c reductase complex 11 kDa protein, mitochondrial precursor (EC 1.10.2.2) (Mitochondrial hinge protein) (Cytochrome c1 nonheme 11 kDa protein) (Complex III subunit VIII).

BCOR_MOUSE
NC score	0.008906 (rank : 204)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	157	Target Neighborhood Hits	521	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

HDAC5_HUMAN
NC score	0.008641 (rank : 205)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	157	Target Neighborhood Hits	353	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

OGFR_HUMAN
NC score	0.008632 (rank : 206)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	157	Target Neighborhood Hits	1582	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BBX_MOUSE
NC score	0.008533 (rank : 207)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	157	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

GNL3_MOUSE
NC score	0.008413 (rank : 208)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	157	Target Neighborhood Hits	99	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

TRPS1_HUMAN
NC score	0.008271 (rank : 209)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	157	Target Neighborhood Hits	539	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

SIA7A_MOUSE
NC score	0.008225 (rank : 210)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	157	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

CHD5_HUMAN
NC score	0.007965 (rank : 211)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	157	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

DIDO1_HUMAN
NC score	0.007573 (rank : 212)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	157	Target Neighborhood Hits	960	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NOP5_HUMAN
NC score	0.007330 (rank : 213)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

HSH2D_MOUSE
NC score	0.007047 (rank : 214)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	157	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MELPH_MOUSE
NC score	0.006696 (rank : 215)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	157	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

TBP_HUMAN
NC score	0.006513 (rank : 216)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	157	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P20226, Q16845, Q9UC02	Gene names	TBP, TF2D, TFIID
Domain Architecture
Description	TATA-box-binding protein (TATA-box factor) (TATA-binding factor) (TATA sequence-binding protein) (Transcription initiation factor TFIID TBP subunit).

GPR98_MOUSE
NC score	0.006457 (rank : 217)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	157	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

UE1D1_MOUSE
NC score	0.005398 (rank : 218)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	157	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

ZN750_MOUSE
NC score	0.004708 (rank : 219)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	157	Target Neighborhood Hits	346	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

R3HD2_MOUSE
NC score	0.004487 (rank : 220)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	157	Target Neighborhood Hits	397	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

PRDM2_HUMAN
NC score	0.004180 (rank : 221)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	157	Target Neighborhood Hits	1135	Shared Neighborhood Hits	31
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

UBP43_MOUSE
NC score	0.004057 (rank : 222)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	157	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

TSH1_MOUSE
NC score	0.003997 (rank : 223)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	157	Target Neighborhood Hits	675	Shared Neighborhood Hits	15
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

PARP2_HUMAN
NC score	0.003776 (rank : 224)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	157	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

DTX2_HUMAN
NC score	0.003612 (rank : 225)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	157	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

RBM19_HUMAN
NC score	0.003497 (rank : 226)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	157	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

KCD17_HUMAN
NC score	0.003103 (rank : 227)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	157	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

KBTB9_HUMAN
NC score	0.002046 (rank : 228)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	157	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KBTB9_MOUSE
NC score	0.001456 (rank : 229)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

FBXW7_HUMAN
NC score	-0.000215 (rank : 230)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	157	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

TCF8_MOUSE
NC score	-0.003045 (rank : 231)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	157	Target Neighborhood Hits	1067	Shared Neighborhood Hits	27
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

ZN406_MOUSE
NC score	-0.004787 (rank : 232)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	157	Target Neighborhood Hits	800	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

ZN394_MOUSE
NC score	-0.005577 (rank : 233)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	157	Target Neighborhood Hits	738	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1D9, Q3U4Z1, Q9CYV9, Q9CZG8	Gene names	Znf394, Zfp94, Zfp99
Domain Architecture
Description	Zinc finger protein 394 (Zinc finger protein 94) (Zfp-94).

PAK4_MOUSE
NC score	-0.005592 (rank : 234)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	157	Target Neighborhood Hits	1098	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).