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Network neighborhood for query Sequence : NEBL_HUMAN

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NEBL_HUMAN
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NEBL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	457	Target Neighborhood Hits	457	Shared Neighborhood Hits	457
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	0 (rank : 2)	NC score	0.815639 (rank : 2)
Query Neighborhood Hits	457	Target Neighborhood Hits	420	Shared Neighborhood Hits	232
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NRAP_MOUSE
θ value	5.55816e-50 (rank : 3)	NC score	0.529674 (rank : 5)
Query Neighborhood Hits	457	Target Neighborhood Hits	167	Shared Neighborhood Hits	39
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

NRAP_HUMAN
θ value	3.37202e-47 (rank : 4)	NC score	0.521289 (rank : 8)
Query Neighborhood Hits	457	Target Neighborhood Hits	159	Shared Neighborhood Hits	29
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

LASP1_MOUSE
θ value	1.4233e-29 (rank : 5)	NC score	0.647617 (rank : 3)
Query Neighborhood Hits	457	Target Neighborhood Hits	297	Shared Neighborhood Hits	171
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_HUMAN
θ value	3.28125e-26 (rank : 6)	NC score	0.644977 (rank : 4)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	171
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

EEA1_HUMAN
θ value	1.2105e-12 (rank : 7)	NC score	0.305105 (rank : 91)
Query Neighborhood Hits	457	Target Neighborhood Hits	1796	Shared Neighborhood Hits	256
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ERC2_MOUSE
θ value	7.34386e-10 (rank : 8)	NC score	0.310839 (rank : 84)
Query Neighborhood Hits	457	Target Neighborhood Hits	1166	Shared Neighborhood Hits	235
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

SRBS1_HUMAN
θ value	9.59137e-10 (rank : 9)	NC score	0.521906 (rank : 7)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	197
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

VINEX_HUMAN
θ value	9.59137e-10 (rank : 10)	NC score	0.526463 (rank : 6)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	172
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

SRBS1_MOUSE
θ value	2.79066e-09 (rank : 11)	NC score	0.512886 (rank : 11)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	184
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_MOUSE
θ value	4.76016e-09 (rank : 12)	NC score	0.511931 (rank : 12)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	168
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

VINEX_MOUSE
θ value	8.11959e-09 (rank : 13)	NC score	0.520792 (rank : 9)
Query Neighborhood Hits	457	Target Neighborhood Hits	286	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRC8_HUMAN
θ value	1.38499e-08 (rank : 14)	NC score	0.516506 (rank : 10)
Query Neighborhood Hits	457	Target Neighborhood Hits	269	Shared Neighborhood Hits	170
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

EEA1_MOUSE
θ value	4.0297e-08 (rank : 15)	NC score	0.309423 (rank : 85)
Query Neighborhood Hits	457	Target Neighborhood Hits	1637	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

PACN3_HUMAN
θ value	1.99992e-07 (rank : 16)	NC score	0.480821 (rank : 19)
Query Neighborhood Hits	457	Target Neighborhood Hits	385	Shared Neighborhood Hits	220
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	1.99992e-07 (rank : 17)	NC score	0.481321 (rank : 18)
Query Neighborhood Hits	457	Target Neighborhood Hits	380	Shared Neighborhood Hits	225
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

DBNL_MOUSE
θ value	4.45536e-07 (rank : 18)	NC score	0.466310 (rank : 30)
Query Neighborhood Hits	457	Target Neighborhood Hits	306	Shared Neighborhood Hits	161
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

PPIP1_MOUSE
θ value	7.59969e-07 (rank : 19)	NC score	0.500228 (rank : 13)
Query Neighborhood Hits	457	Target Neighborhood Hits	377	Shared Neighborhood Hits	238
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

DBNL_HUMAN
θ value	9.92553e-07 (rank : 20)	NC score	0.469741 (rank : 27)
Query Neighborhood Hits	457	Target Neighborhood Hits	244	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

PACN2_MOUSE
θ value	9.92553e-07 (rank : 21)	NC score	0.489192 (rank : 15)
Query Neighborhood Hits	457	Target Neighborhood Hits	382	Shared Neighborhood Hits	219
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

GRB2_MOUSE
θ value	1.69304e-06 (rank : 22)	NC score	0.409467 (rank : 46)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	163
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

MYH1_MOUSE
θ value	1.69304e-06 (rank : 23)	NC score	0.286307 (rank : 128)
Query Neighborhood Hits	457	Target Neighborhood Hits	1461	Shared Neighborhood Hits	242
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

PACN1_HUMAN
θ value	1.69304e-06 (rank : 24)	NC score	0.477100 (rank : 22)
Query Neighborhood Hits	457	Target Neighborhood Hits	320	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PPIP1_HUMAN
θ value	1.69304e-06 (rank : 25)	NC score	0.496457 (rank : 14)
Query Neighborhood Hits	457	Target Neighborhood Hits	389	Shared Neighborhood Hits	242
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

ABI2_HUMAN
θ value	2.21117e-06 (rank : 26)	NC score	0.471031 (rank : 25)
Query Neighborhood Hits	457	Target Neighborhood Hits	350	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	2.21117e-06 (rank : 27)	NC score	0.477560 (rank : 20)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	159
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

GRB2_HUMAN
θ value	2.21117e-06 (rank : 28)	NC score	0.410450 (rank : 44)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	163
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

PACN2_HUMAN
θ value	2.21117e-06 (rank : 29)	NC score	0.486193 (rank : 16)
Query Neighborhood Hits	457	Target Neighborhood Hits	339	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

ABI1_MOUSE
θ value	2.88788e-06 (rank : 30)	NC score	0.471042 (rank : 24)
Query Neighborhood Hits	457	Target Neighborhood Hits	246	Shared Neighborhood Hits	155
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

PACN1_MOUSE
θ value	3.77169e-06 (rank : 31)	NC score	0.468156 (rank : 28)
Query Neighborhood Hits	457	Target Neighborhood Hits	283	Shared Neighborhood Hits	183
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

CENPE_HUMAN
θ value	4.92598e-06 (rank : 32)	NC score	0.272318 (rank : 194)
Query Neighborhood Hits	457	Target Neighborhood Hits	2060	Shared Neighborhood Hits	280
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RB6I2_MOUSE
θ value	4.92598e-06 (rank : 33)	NC score	0.303164 (rank : 92)
Query Neighborhood Hits	457	Target Neighborhood Hits	1433	Shared Neighborhood Hits	245
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

STS1_MOUSE
θ value	4.92598e-06 (rank : 34)	NC score	0.279388 (rank : 159)
Query Neighborhood Hits	457	Target Neighborhood Hits	104	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

HCLS1_MOUSE
θ value	6.43352e-06 (rank : 35)	NC score	0.483495 (rank : 17)
Query Neighborhood Hits	457	Target Neighborhood Hits	329	Shared Neighborhood Hits	156
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

LUZP1_HUMAN
θ value	6.43352e-06 (rank : 36)	NC score	0.276686 (rank : 177)
Query Neighborhood Hits	457	Target Neighborhood Hits	739	Shared Neighborhood Hits	181
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

ABI1_HUMAN
θ value	8.40245e-06 (rank : 37)	NC score	0.455136 (rank : 35)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ITSN2_MOUSE
θ value	8.40245e-06 (rank : 38)	NC score	0.438100 (rank : 39)
Query Neighborhood Hits	457	Target Neighborhood Hits	1371	Shared Neighborhood Hits	370
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHG7_HUMAN
θ value	1.09739e-05 (rank : 39)	NC score	0.383133 (rank : 54)
Query Neighborhood Hits	457	Target Neighborhood Hits	347	Shared Neighborhood Hits	183
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

MYH4_MOUSE
θ value	1.09739e-05 (rank : 40)	NC score	0.282544 (rank : 141)
Query Neighborhood Hits	457	Target Neighborhood Hits	1476	Shared Neighborhood Hits	244
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

STS1_HUMAN
θ value	1.09739e-05 (rank : 41)	NC score	0.277809 (rank : 169)
Query Neighborhood Hits	457	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

HCLS1_HUMAN
θ value	1.43324e-05 (rank : 42)	NC score	0.477255 (rank : 21)
Query Neighborhood Hits	457	Target Neighborhood Hits	358	Shared Neighborhood Hits	152
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ITSN2_HUMAN
θ value	1.43324e-05 (rank : 43)	NC score	0.430165 (rank : 43)
Query Neighborhood Hits	457	Target Neighborhood Hits	1173	Shared Neighborhood Hits	337
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SH3G2_HUMAN
θ value	1.87187e-05 (rank : 44)	NC score	0.472726 (rank : 23)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	198
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SMC1A_MOUSE
θ value	1.87187e-05 (rank : 45)	NC score	0.299526 (rank : 98)
Query Neighborhood Hits	457	Target Neighborhood Hits	1384	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TRDN_HUMAN
θ value	1.87187e-05 (rank : 46)	NC score	0.197778 (rank : 478)
Query Neighborhood Hits	457	Target Neighborhood Hits	542	Shared Neighborhood Hits	123
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

CYTSA_MOUSE
θ value	2.44474e-05 (rank : 47)	NC score	0.277599 (rank : 170)
Query Neighborhood Hits	457	Target Neighborhood Hits	1104	Shared Neighborhood Hits	227
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

MYH10_HUMAN
θ value	2.44474e-05 (rank : 48)	NC score	0.273964 (rank : 190)
Query Neighborhood Hits	457	Target Neighborhood Hits	1620	Shared Neighborhood Hits	252
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RHG26_HUMAN
θ value	2.44474e-05 (rank : 49)	NC score	0.230504 (rank : 348)
Query Neighborhood Hits	457	Target Neighborhood Hits	281	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

STS2_HUMAN
θ value	2.44474e-05 (rank : 50)	NC score	0.300815 (rank : 96)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SH3G2_MOUSE
θ value	3.19293e-05 (rank : 51)	NC score	0.463409 (rank : 32)
Query Neighborhood Hits	457	Target Neighborhood Hits	319	Shared Neighborhood Hits	192
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_MOUSE
θ value	3.19293e-05 (rank : 52)	NC score	0.460636 (rank : 34)
Query Neighborhood Hits	457	Target Neighborhood Hits	236	Shared Neighborhood Hits	165
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3G3_HUMAN
θ value	4.1701e-05 (rank : 53)	NC score	0.449443 (rank : 36)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	163
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

CE290_HUMAN
θ value	5.44631e-05 (rank : 54)	NC score	0.302688 (rank : 94)
Query Neighborhood Hits	457	Target Neighborhood Hits	1553	Shared Neighborhood Hits	246
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

FYN_HUMAN
θ value	5.44631e-05 (rank : 55)	NC score	0.137521 (rank : 716)
Query Neighborhood Hits	457	Target Neighborhood Hits	1078	Shared Neighborhood Hits	168
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	5.44631e-05 (rank : 56)	NC score	0.139712 (rank : 702)
Query Neighborhood Hits	457	Target Neighborhood Hits	1073	Shared Neighborhood Hits	168
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

KTN1_HUMAN
θ value	5.44631e-05 (rank : 57)	NC score	0.289391 (rank : 120)
Query Neighborhood Hits	457	Target Neighborhood Hits	1197	Shared Neighborhood Hits	225
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYH13_HUMAN
θ value	5.44631e-05 (rank : 58)	NC score	0.288695 (rank : 121)
Query Neighborhood Hits	457	Target Neighborhood Hits	1504	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_HUMAN
θ value	5.44631e-05 (rank : 59)	NC score	0.282369 (rank : 143)
Query Neighborhood Hits	457	Target Neighborhood Hits	1478	Shared Neighborhood Hits	243
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

OSTF1_MOUSE
θ value	5.44631e-05 (rank : 60)	NC score	0.347425 (rank : 72)
Query Neighborhood Hits	457	Target Neighborhood Hits	467	Shared Neighborhood Hits	167
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PIBF1_HUMAN
θ value	5.44631e-05 (rank : 61)	NC score	0.308123 (rank : 87)
Query Neighborhood Hits	457	Target Neighborhood Hits	1041	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

SMC1A_HUMAN
θ value	5.44631e-05 (rank : 62)	NC score	0.293797 (rank : 108)
Query Neighborhood Hits	457	Target Neighborhood Hits	1346	Shared Neighborhood Hits	252
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SYCP1_HUMAN
θ value	5.44631e-05 (rank : 63)	NC score	0.299882 (rank : 97)
Query Neighborhood Hits	457	Target Neighborhood Hits	1313	Shared Neighborhood Hits	242
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

KTN1_MOUSE
θ value	7.1131e-05 (rank : 64)	NC score	0.307583 (rank : 89)
Query Neighborhood Hits	457	Target Neighborhood Hits	1324	Shared Neighborhood Hits	241
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH2_HUMAN
θ value	7.1131e-05 (rank : 65)	NC score	0.283044 (rank : 140)
Query Neighborhood Hits	457	Target Neighborhood Hits	1491	Shared Neighborhood Hits	243
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH8_MOUSE
θ value	7.1131e-05 (rank : 66)	NC score	0.283377 (rank : 139)
Query Neighborhood Hits	457	Target Neighborhood Hits	1600	Shared Neighborhood Hits	258
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

OSTF1_HUMAN
θ value	7.1131e-05 (rank : 67)	NC score	0.354115 (rank : 68)
Query Neighborhood Hits	457	Target Neighborhood Hits	466	Shared Neighborhood Hits	167
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

CYTSA_HUMAN
θ value	9.29e-05 (rank : 68)	NC score	0.276191 (rank : 179)
Query Neighborhood Hits	457	Target Neighborhood Hits	1138	Shared Neighborhood Hits	229
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

SRC_HUMAN
θ value	9.29e-05 (rank : 69)	NC score	0.135747 (rank : 727)
Query Neighborhood Hits	457	Target Neighborhood Hits	1058	Shared Neighborhood Hits	166
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

ITSN1_MOUSE
θ value	0.000121331 (rank : 70)	NC score	0.433608 (rank : 40)
Query Neighborhood Hits	457	Target Neighborhood Hits	1669	Shared Neighborhood Hits	393
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CD2AP_MOUSE
θ value	0.000158464 (rank : 71)	NC score	0.470231 (rank : 26)
Query Neighborhood Hits	457	Target Neighborhood Hits	336	Shared Neighborhood Hits	187
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

GCC2_HUMAN
θ value	0.000158464 (rank : 72)	NC score	0.285453 (rank : 131)
Query Neighborhood Hits	457	Target Neighborhood Hits	1558	Shared Neighborhood Hits	250
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GRAP2_MOUSE
θ value	0.000158464 (rank : 73)	NC score	0.404246 (rank : 49)
Query Neighborhood Hits	457	Target Neighborhood Hits	297	Shared Neighborhood Hits	162
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ITSN1_HUMAN
θ value	0.000158464 (rank : 74)	NC score	0.432985 (rank : 41)
Query Neighborhood Hits	457	Target Neighborhood Hits	1757	Shared Neighborhood Hits	389
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

M3KL4_HUMAN
θ value	0.000158464 (rank : 75)	NC score	0.138166 (rank : 712)
Query Neighborhood Hits	457	Target Neighborhood Hits	1087	Shared Neighborhood Hits	210
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

RBP24_HUMAN
θ value	0.000158464 (rank : 76)	NC score	0.285606 (rank : 130)
Query Neighborhood Hits	457	Target Neighborhood Hits	1559	Shared Neighborhood Hits	248
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CRKL_HUMAN
θ value	0.000270298 (rank : 77)	NC score	0.374840 (rank : 57)
Query Neighborhood Hits	457	Target Neighborhood Hits	313	Shared Neighborhood Hits	151
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	0.000270298 (rank : 78)	NC score	0.370229 (rank : 59)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	148
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

PLEC1_HUMAN
θ value	0.000270298 (rank : 79)	NC score	0.225767 (rank : 372)
Query Neighborhood Hits	457	Target Neighborhood Hits	1326	Shared Neighborhood Hits	213
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RB6I2_HUMAN
θ value	0.000270298 (rank : 80)	NC score	0.302945 (rank : 93)
Query Neighborhood Hits	457	Target Neighborhood Hits	1584	Shared Neighborhood Hits	259
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CYLC2_HUMAN
θ value	0.00035302 (rank : 81)	NC score	0.147710 (rank : 667)
Query Neighborhood Hits	457	Target Neighborhood Hits	223	Shared Neighborhood Hits	50
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

MYO1E_HUMAN
θ value	0.00035302 (rank : 82)	NC score	0.293658 (rank : 109)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	182
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

RAD50_HUMAN
θ value	0.00035302 (rank : 83)	NC score	0.312894 (rank : 82)
Query Neighborhood Hits	457	Target Neighborhood Hits	1317	Shared Neighborhood Hits	248
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SH3G1_MOUSE
θ value	0.00035302 (rank : 84)	NC score	0.440673 (rank : 38)
Query Neighborhood Hits	457	Target Neighborhood Hits	291	Shared Neighborhood Hits	181
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SYCP1_MOUSE
θ value	0.00035302 (rank : 85)	NC score	0.296457 (rank : 104)
Query Neighborhood Hits	457	Target Neighborhood Hits	1456	Shared Neighborhood Hits	254
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRHY_HUMAN
θ value	0.00035302 (rank : 86)	NC score	0.259939 (rank : 227)
Query Neighborhood Hits	457	Target Neighborhood Hits	1385	Shared Neighborhood Hits	225
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ARHG7_MOUSE
θ value	0.000461057 (rank : 87)	NC score	0.396352 (rank : 50)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	222
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

GRAP_HUMAN
θ value	0.000461057 (rank : 88)	NC score	0.382714 (rank : 55)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	159
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

LIPB1_HUMAN
θ value	0.000461057 (rank : 89)	NC score	0.223488 (rank : 378)
Query Neighborhood Hits	457	Target Neighborhood Hits	640	Shared Neighborhood Hits	177
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

SHLB1_MOUSE
θ value	0.000461057 (rank : 90)	NC score	0.252086 (rank : 263)
Query Neighborhood Hits	457	Target Neighborhood Hits	101	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

CD2AP_HUMAN
θ value	0.000602161 (rank : 91)	NC score	0.467363 (rank : 29)
Query Neighborhood Hits	457	Target Neighborhood Hits	315	Shared Neighborhood Hits	185
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

MOES_MOUSE
θ value	0.000602161 (rank : 92)	NC score	0.181718 (rank : 534)
Query Neighborhood Hits	457	Target Neighborhood Hits	923	Shared Neighborhood Hits	202
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RAI14_HUMAN
θ value	0.000602161 (rank : 93)	NC score	0.201728 (rank : 464)
Query Neighborhood Hits	457	Target Neighborhood Hits	1367	Shared Neighborhood Hits	217
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SH3G1_HUMAN
θ value	0.000602161 (rank : 94)	NC score	0.448601 (rank : 37)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	196
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3K1_HUMAN
θ value	0.000602161 (rank : 95)	NC score	0.463431 (rank : 31)
Query Neighborhood Hits	457	Target Neighborhood Hits	341	Shared Neighborhood Hits	189
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	0.000602161 (rank : 96)	NC score	0.462163 (rank : 33)
Query Neighborhood Hits	457	Target Neighborhood Hits	332	Shared Neighborhood Hits	195
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

GOGB1_HUMAN
θ value	0.000786445 (rank : 97)	NC score	0.288251 (rank : 122)
Query Neighborhood Hits	457	Target Neighborhood Hits	2297	Shared Neighborhood Hits	284
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

P85A_MOUSE
θ value	0.000786445 (rank : 98)	NC score	0.216973 (rank : 406)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	169
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PEX13_HUMAN
θ value	0.000786445 (rank : 99)	NC score	0.347716 (rank : 71)
Query Neighborhood Hits	457	Target Neighborhood Hits	128	Shared Neighborhood Hits	106
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ROCK1_HUMAN
θ value	0.000786445 (rank : 100)	NC score	0.156535 (rank : 629)
Query Neighborhood Hits	457	Target Neighborhood Hits	2000	Shared Neighborhood Hits	261
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

VAV_HUMAN
θ value	0.000786445 (rank : 101)	NC score	0.329059 (rank : 79)
Query Neighborhood Hits	457	Target Neighborhood Hits	452	Shared Neighborhood Hits	177
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

CTRO_HUMAN
θ value	0.00102713 (rank : 102)	NC score	0.154693 (rank : 632)
Query Neighborhood Hits	457	Target Neighborhood Hits	2092	Shared Neighborhood Hits	262
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MYH4_HUMAN
θ value	0.00102713 (rank : 103)	NC score	0.277284 (rank : 174)
Query Neighborhood Hits	457	Target Neighborhood Hits	1377	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

RAD50_MOUSE
θ value	0.00102713 (rank : 104)	NC score	0.310916 (rank : 83)
Query Neighborhood Hits	457	Target Neighborhood Hits	1366	Shared Neighborhood Hits	250
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

DJC18_HUMAN
θ value	0.00134147 (rank : 105)	NC score	0.052394 (rank : 1496)
Query Neighborhood Hits	457	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H819	Gene names	DNAJC18
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 18.

GRAP2_HUMAN
θ value	0.00134147 (rank : 106)	NC score	0.393401 (rank : 51)
Query Neighborhood Hits	457	Target Neighborhood Hits	304	Shared Neighborhood Hits	160
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

MAP1B_HUMAN
θ value	0.00134147 (rank : 107)	NC score	0.164124 (rank : 602)
Query Neighborhood Hits	457	Target Neighborhood Hits	903	Shared Neighborhood Hits	139
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SHLB1_HUMAN
θ value	0.00134147 (rank : 108)	NC score	0.243401 (rank : 290)
Query Neighborhood Hits	457	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SRC_MOUSE
θ value	0.00134147 (rank : 109)	NC score	0.121005 (rank : 806)
Query Neighborhood Hits	457	Target Neighborhood Hits	1033	Shared Neighborhood Hits	156
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

AHI1_MOUSE
θ value	0.00175202 (rank : 110)	NC score	0.291982 (rank : 114)
Query Neighborhood Hits	457	Target Neighborhood Hits	496	Shared Neighborhood Hits	159
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

GOGA5_MOUSE
θ value	0.00175202 (rank : 111)	NC score	0.276452 (rank : 178)
Query Neighborhood Hits	457	Target Neighborhood Hits	1434	Shared Neighborhood Hits	240
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MYO1F_HUMAN
θ value	0.00175202 (rank : 112)	NC score	0.298703 (rank : 100)
Query Neighborhood Hits	457	Target Neighborhood Hits	275	Shared Neighborhood Hits	176
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

STAC_HUMAN
θ value	0.00175202 (rank : 113)	NC score	0.363217 (rank : 63)
Query Neighborhood Hits	457	Target Neighborhood Hits	276	Shared Neighborhood Hits	152
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CING_HUMAN
θ value	0.00228821 (rank : 114)	NC score	0.281614 (rank : 145)
Query Neighborhood Hits	457	Target Neighborhood Hits	1275	Shared Neighborhood Hits	239
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DJC18_MOUSE
θ value	0.00228821 (rank : 115)	NC score	0.053446 (rank : 1476)
Query Neighborhood Hits	457	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CZJ9, Q8R371	Gene names	Dnajc18
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 18.

FLIP1_HUMAN
θ value	0.00228821 (rank : 116)	NC score	0.291532 (rank : 116)
Query Neighborhood Hits	457	Target Neighborhood Hits	1405	Shared Neighborhood Hits	254
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

P85A_HUMAN
θ value	0.00228821 (rank : 117)	NC score	0.219127 (rank : 392)
Query Neighborhood Hits	457	Target Neighborhood Hits	479	Shared Neighborhood Hits	185
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

ROCK1_MOUSE
θ value	0.00228821 (rank : 118)	NC score	0.167351 (rank : 583)
Query Neighborhood Hits	457	Target Neighborhood Hits	2126	Shared Neighborhood Hits	278
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

STAC_MOUSE
θ value	0.00228821 (rank : 119)	NC score	0.356590 (rank : 66)
Query Neighborhood Hits	457	Target Neighborhood Hits	268	Shared Neighborhood Hits	150
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV_MOUSE
θ value	0.00228821 (rank : 120)	NC score	0.325971 (rank : 80)
Query Neighborhood Hits	457	Target Neighborhood Hits	430	Shared Neighborhood Hits	173
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

MY18A_MOUSE
θ value	0.00298849 (rank : 121)	NC score	0.285280 (rank : 132)
Query Neighborhood Hits	457	Target Neighborhood Hits	1989	Shared Neighborhood Hits	269
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYO1F_MOUSE
θ value	0.00298849 (rank : 122)	NC score	0.298319 (rank : 101)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	175
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

PLCG2_HUMAN
θ value	0.00298849 (rank : 123)	NC score	0.294283 (rank : 107)
Query Neighborhood Hits	457	Target Neighborhood Hits	280	Shared Neighborhood Hits	142
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

STAM2_MOUSE
θ value	0.00298849 (rank : 124)	NC score	0.353203 (rank : 69)
Query Neighborhood Hits	457	Target Neighborhood Hits	285	Shared Neighborhood Hits	160
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

DNMBP_HUMAN
θ value	0.00390308 (rank : 125)	NC score	0.366826 (rank : 61)
Query Neighborhood Hits	457	Target Neighborhood Hits	413	Shared Neighborhood Hits	203
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
θ value	0.00390308 (rank : 126)	NC score	0.356142 (rank : 67)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	197
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGR_HUMAN
θ value	0.00390308 (rank : 127)	NC score	0.135283 (rank : 729)
Query Neighborhood Hits	457	Target Neighborhood Hits	1067	Shared Neighborhood Hits	166
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GOGA4_HUMAN
θ value	0.00390308 (rank : 128)	NC score	0.292902 (rank : 111)
Query Neighborhood Hits	457	Target Neighborhood Hits	2034	Shared Neighborhood Hits	277
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KIF5C_HUMAN
θ value	0.00390308 (rank : 129)	NC score	0.186846 (rank : 519)
Query Neighborhood Hits	457	Target Neighborhood Hits	974	Shared Neighborhood Hits	218
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MRCKA_HUMAN
θ value	0.00390308 (rank : 130)	NC score	0.145577 (rank : 674)
Query Neighborhood Hits	457	Target Neighborhood Hits	1999	Shared Neighborhood Hits	260
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

NPHP1_MOUSE
θ value	0.00390308 (rank : 131)	NC score	0.342357 (rank : 77)
Query Neighborhood Hits	457	Target Neighborhood Hits	267	Shared Neighborhood Hits	163
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

PEX13_MOUSE
θ value	0.00390308 (rank : 132)	NC score	0.338802 (rank : 78)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

RASA1_HUMAN
θ value	0.00390308 (rank : 133)	NC score	0.167331 (rank : 584)
Query Neighborhood Hits	457	Target Neighborhood Hits	258	Shared Neighborhood Hits	76
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SLK_HUMAN
θ value	0.00390308 (rank : 134)	NC score	0.096143 (rank : 1001)
Query Neighborhood Hits	457	Target Neighborhood Hits	1775	Shared Neighborhood Hits	244
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ABI3_MOUSE
θ value	0.00509761 (rank : 135)	NC score	0.404301 (rank : 48)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	130
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AKAP9_HUMAN
θ value	0.00509761 (rank : 136)	NC score	0.280905 (rank : 149)
Query Neighborhood Hits	457	Target Neighborhood Hits	1710	Shared Neighborhood Hits	255
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR26_HUMAN
θ value	0.00509761 (rank : 137)	NC score	0.253480 (rank : 255)
Query Neighborhood Hits	457	Target Neighborhood Hits	1614	Shared Neighborhood Hits	251
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARHG6_HUMAN
θ value	0.00509761 (rank : 138)	NC score	0.368200 (rank : 60)
Query Neighborhood Hits	457	Target Neighborhood Hits	376	Shared Neighborhood Hits	212
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	0.00509761 (rank : 139)	NC score	0.376367 (rank : 56)
Query Neighborhood Hits	457	Target Neighborhood Hits	394	Shared Neighborhood Hits	216
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHGG_HUMAN
θ value	0.00509761 (rank : 140)	NC score	0.144861 (rank : 679)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CCD46_MOUSE
θ value	0.00509761 (rank : 141)	NC score	0.292104 (rank : 113)
Query Neighborhood Hits	457	Target Neighborhood Hits	1405	Shared Neighborhood Hits	257
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GRAP_MOUSE
θ value	0.00509761 (rank : 142)	NC score	0.383966 (rank : 53)
Query Neighborhood Hits	457	Target Neighborhood Hits	309	Shared Neighborhood Hits	164
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

JIP3_HUMAN
θ value	0.00509761 (rank : 143)	NC score	0.164433 (rank : 601)
Query Neighborhood Hits	457	Target Neighborhood Hits	1039	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MY18B_HUMAN
θ value	0.00509761 (rank : 144)	NC score	0.265827 (rank : 209)
Query Neighborhood Hits	457	Target Neighborhood Hits	1299	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ABI3_HUMAN
θ value	0.00665767 (rank : 145)	NC score	0.405347 (rank : 47)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	131
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AHI1_HUMAN
θ value	0.00665767 (rank : 146)	NC score	0.290039 (rank : 118)
Query Neighborhood Hits	457	Target Neighborhood Hits	537	Shared Neighborhood Hits	171
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ARHG5_HUMAN
θ value	0.00665767 (rank : 147)	NC score	0.196008 (rank : 486)
Query Neighborhood Hits	457	Target Neighborhood Hits	172	Shared Neighborhood Hits	96
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

CYLC1_HUMAN
θ value	0.00665767 (rank : 148)	NC score	0.195286 (rank : 492)
Query Neighborhood Hits	457	Target Neighborhood Hits	408	Shared Neighborhood Hits	96
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MYH3_HUMAN
θ value	0.00665767 (rank : 149)	NC score	0.281601 (rank : 146)
Query Neighborhood Hits	457	Target Neighborhood Hits	1660	Shared Neighborhood Hits	258
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PLCG1_MOUSE
θ value	0.00665767 (rank : 150)	NC score	0.293236 (rank : 110)
Query Neighborhood Hits	457	Target Neighborhood Hits	314	Shared Neighborhood Hits	151
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

RAI14_MOUSE
θ value	0.00665767 (rank : 151)	NC score	0.221011 (rank : 387)
Query Neighborhood Hits	457	Target Neighborhood Hits	1505	Shared Neighborhood Hits	238
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

REST_HUMAN
θ value	0.00665767 (rank : 152)	NC score	0.273777 (rank : 192)
Query Neighborhood Hits	457	Target Neighborhood Hits	1605	Shared Neighborhood Hits	255
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SMC2_MOUSE
θ value	0.00665767 (rank : 153)	NC score	0.283844 (rank : 136)
Query Neighborhood Hits	457	Target Neighborhood Hits	1131	Shared Neighborhood Hits	240
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

UACA_HUMAN
θ value	0.00665767 (rank : 154)	NC score	0.254683 (rank : 251)
Query Neighborhood Hits	457	Target Neighborhood Hits	1622	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

YES_MOUSE
θ value	0.00665767 (rank : 155)	NC score	0.132157 (rank : 751)
Query Neighborhood Hits	457	Target Neighborhood Hits	1052	Shared Neighborhood Hits	162
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

MYH8_HUMAN
θ value	0.00869519 (rank : 156)	NC score	0.283870 (rank : 135)
Query Neighborhood Hits	457	Target Neighborhood Hits	1610	Shared Neighborhood Hits	264
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NCF1_HUMAN
θ value	0.00869519 (rank : 157)	NC score	0.361664 (rank : 65)
Query Neighborhood Hits	457	Target Neighborhood Hits	198	Shared Neighborhood Hits	143
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF4_MOUSE
θ value	0.00869519 (rank : 158)	NC score	0.409658 (rank : 45)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	136
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

STAM2_HUMAN
θ value	0.00869519 (rank : 159)	NC score	0.343800 (rank : 75)
Query Neighborhood Hits	457	Target Neighborhood Hits	288	Shared Neighborhood Hits	160
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

VAV2_MOUSE
θ value	0.00869519 (rank : 160)	NC score	0.308714 (rank : 86)
Query Neighborhood Hits	457	Target Neighborhood Hits	456	Shared Neighborhood Hits	172
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

YES_HUMAN
θ value	0.00869519 (rank : 161)	NC score	0.130924 (rank : 760)
Query Neighborhood Hits	457	Target Neighborhood Hits	1059	Shared Neighborhood Hits	162
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

HCK_MOUSE
θ value	0.0113563 (rank : 162)	NC score	0.116907 (rank : 836)
Query Neighborhood Hits	457	Target Neighborhood Hits	1029	Shared Neighborhood Hits	161
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

MAP1B_MOUSE
θ value	0.0113563 (rank : 163)	NC score	0.190402 (rank : 505)
Query Neighborhood Hits	457	Target Neighborhood Hits	977	Shared Neighborhood Hits	153
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MPP8_HUMAN
θ value	0.0113563 (rank : 164)	NC score	0.144031 (rank : 684)
Query Neighborhood Hits	457	Target Neighborhood Hits	948	Shared Neighborhood Hits	177
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYH6_HUMAN
θ value	0.0113563 (rank : 165)	NC score	0.279855 (rank : 152)
Query Neighborhood Hits	457	Target Neighborhood Hits	1426	Shared Neighborhood Hits	237
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NCF1_MOUSE
θ value	0.0113563 (rank : 166)	NC score	0.362506 (rank : 64)
Query Neighborhood Hits	457	Target Neighborhood Hits	198	Shared Neighborhood Hits	146
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

ANM2_HUMAN
θ value	0.0148317 (rank : 167)	NC score	0.223579 (rank : 377)
Query Neighborhood Hits	457	Target Neighborhood Hits	175	Shared Neighborhood Hits	127
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

BPAEA_MOUSE
θ value	0.0148317 (rank : 168)	NC score	0.275879 (rank : 181)
Query Neighborhood Hits	457	Target Neighborhood Hits	1480	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYH10_MOUSE
θ value	0.0148317 (rank : 169)	NC score	0.271874 (rank : 195)
Query Neighborhood Hits	457	Target Neighborhood Hits	1612	Shared Neighborhood Hits	250
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	0.0148317 (rank : 170)	NC score	0.279514 (rank : 156)
Query Neighborhood Hits	457	Target Neighborhood Hits	1806	Shared Neighborhood Hits	275
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
θ value	0.0148317 (rank : 171)	NC score	0.274592 (rank : 189)
Query Neighborhood Hits	457	Target Neighborhood Hits	1829	Shared Neighborhood Hits	266
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

VAV2_HUMAN
θ value	0.0148317 (rank : 172)	NC score	0.307049 (rank : 90)
Query Neighborhood Hits	457	Target Neighborhood Hits	453	Shared Neighborhood Hits	174
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

LIPB1_MOUSE
θ value	0.0193708 (rank : 173)	NC score	0.230866 (rank : 341)
Query Neighborhood Hits	457	Target Neighborhood Hits	727	Shared Neighborhood Hits	184
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MYH6_MOUSE
θ value	0.0193708 (rank : 174)	NC score	0.279797 (rank : 153)
Query Neighborhood Hits	457	Target Neighborhood Hits	1501	Shared Neighborhood Hits	246
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NCF4_HUMAN
θ value	0.0193708 (rank : 175)	NC score	0.385558 (rank : 52)
Query Neighborhood Hits	457	Target Neighborhood Hits	161	Shared Neighborhood Hits	123
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NUMA1_HUMAN
θ value	0.0193708 (rank : 176)	NC score	0.277506 (rank : 171)
Query Neighborhood Hits	457	Target Neighborhood Hits	1523	Shared Neighborhood Hits	244
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RUSC1_HUMAN
θ value	0.0193708 (rank : 177)	NC score	0.263180 (rank : 216)
Query Neighborhood Hits	457	Target Neighborhood Hits	226	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

ITK_MOUSE
θ value	0.0252991 (rank : 178)	NC score	0.074759 (rank : 1202)
Query Neighborhood Hits	457	Target Neighborhood Hits	985	Shared Neighborhood Hits	114
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

MYH7_HUMAN
θ value	0.0252991 (rank : 179)	NC score	0.278892 (rank : 162)
Query Neighborhood Hits	457	Target Neighborhood Hits	1559	Shared Neighborhood Hits	245
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NCK1_HUMAN
θ value	0.0252991 (rank : 180)	NC score	0.371844 (rank : 58)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	163
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NFM_HUMAN
θ value	0.0252991 (rank : 181)	NC score	0.166626 (rank : 588)
Query Neighborhood Hits	457	Target Neighborhood Hits	1328	Shared Neighborhood Hits	231
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

ANR12_HUMAN
θ value	0.0330416 (rank : 182)	NC score	0.163966 (rank : 604)
Query Neighborhood Hits	457	Target Neighborhood Hits	1081	Shared Neighborhood Hits	199
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CRK_HUMAN
θ value	0.0330416 (rank : 183)	NC score	0.343403 (rank : 76)
Query Neighborhood Hits	457	Target Neighborhood Hits	308	Shared Neighborhood Hits	155
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	0.0330416 (rank : 184)	NC score	0.346314 (rank : 74)
Query Neighborhood Hits	457	Target Neighborhood Hits	314	Shared Neighborhood Hits	155
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PLCG1_HUMAN
θ value	0.0330416 (rank : 185)	NC score	0.277971 (rank : 167)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	141
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SFR12_HUMAN
θ value	0.0330416 (rank : 186)	NC score	0.151296 (rank : 650)
Query Neighborhood Hits	457	Target Neighborhood Hits	553	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ANM2_MOUSE
θ value	0.0431538 (rank : 187)	NC score	0.211644 (rank : 427)
Query Neighborhood Hits	457	Target Neighborhood Hits	175	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ATRX_HUMAN
θ value	0.0431538 (rank : 188)	NC score	0.122549 (rank : 801)
Query Neighborhood Hits	457	Target Neighborhood Hits	842	Shared Neighborhood Hits	165
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DDEF1_MOUSE
θ value	0.0431538 (rank : 189)	NC score	0.198079 (rank : 476)
Query Neighborhood Hits	457	Target Neighborhood Hits	592	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	0.0431538 (rank : 190)	NC score	0.187937 (rank : 515)
Query Neighborhood Hits	457	Target Neighborhood Hits	599	Shared Neighborhood Hits	159
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DNJC7_MOUSE
θ value	0.0431538 (rank : 191)	NC score	0.041279 (rank : 1535)
Query Neighborhood Hits	457	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

DOCK1_HUMAN
θ value	0.0431538 (rank : 192)	NC score	0.145706 (rank : 670)
Query Neighborhood Hits	457	Target Neighborhood Hits	191	Shared Neighborhood Hits	118
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

EP15_MOUSE
θ value	0.0431538 (rank : 193)	NC score	0.217396 (rank : 403)
Query Neighborhood Hits	457	Target Neighborhood Hits	820	Shared Neighborhood Hits	178
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GOGA5_HUMAN
θ value	0.0431538 (rank : 194)	NC score	0.277914 (rank : 168)
Query Neighborhood Hits	457	Target Neighborhood Hits	1168	Shared Neighborhood Hits	226
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

IASPP_MOUSE
θ value	0.0431538 (rank : 195)	NC score	0.188848 (rank : 511)
Query Neighborhood Hits	457	Target Neighborhood Hits	1024	Shared Neighborhood Hits	158
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

M3K10_HUMAN
θ value	0.0431538 (rank : 196)	NC score	0.111808 (rank : 868)
Query Neighborhood Hits	457	Target Neighborhood Hits	1071	Shared Neighborhood Hits	179
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

NFM_MOUSE
θ value	0.0431538 (rank : 197)	NC score	0.168353 (rank : 579)
Query Neighborhood Hits	457	Target Neighborhood Hits	1159	Shared Neighborhood Hits	224
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

OFD1_HUMAN
θ value	0.0431538 (rank : 198)	NC score	0.268334 (rank : 203)
Query Neighborhood Hits	457	Target Neighborhood Hits	753	Shared Neighborhood Hits	197
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

REST_MOUSE
θ value	0.0431538 (rank : 199)	NC score	0.273520 (rank : 193)
Query Neighborhood Hits	457	Target Neighborhood Hits	1506	Shared Neighborhood Hits	251
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

HCK_HUMAN
θ value	0.0563607 (rank : 200)	NC score	0.115145 (rank : 850)
Query Neighborhood Hits	457	Target Neighborhood Hits	1035	Shared Neighborhood Hits	159
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

IASPP_HUMAN
θ value	0.0563607 (rank : 201)	NC score	0.207929 (rank : 445)
Query Neighborhood Hits	457	Target Neighborhood Hits	688	Shared Neighborhood Hits	150
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LUZP1_MOUSE
θ value	0.0563607 (rank : 202)	NC score	0.278757 (rank : 165)
Query Neighborhood Hits	457	Target Neighborhood Hits	940	Shared Neighborhood Hits	213
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

SNX18_HUMAN
θ value	0.0563607 (rank : 203)	NC score	0.287096 (rank : 127)
Query Neighborhood Hits	457	Target Neighborhood Hits	207	Shared Neighborhood Hits	126
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	0.0563607 (rank : 204)	NC score	0.291661 (rank : 115)
Query Neighborhood Hits	457	Target Neighborhood Hits	198	Shared Neighborhood Hits	124
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

ANR18_HUMAN
θ value	0.0736092 (rank : 205)	NC score	0.196953 (rank : 481)
Query Neighborhood Hits	457	Target Neighborhood Hits	1106	Shared Neighborhood Hits	221
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ARHGG_MOUSE
θ value	0.0736092 (rank : 206)	NC score	0.162257 (rank : 614)
Query Neighborhood Hits	457	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CCD11_HUMAN
θ value	0.0736092 (rank : 207)	NC score	0.264740 (rank : 212)
Query Neighborhood Hits	457	Target Neighborhood Hits	822	Shared Neighborhood Hits	207
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

E41L2_MOUSE
θ value	0.0736092 (rank : 208)	NC score	0.055012 (rank : 1449)
Query Neighborhood Hits	457	Target Neighborhood Hits	459	Shared Neighborhood Hits	92
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FRK_HUMAN
θ value	0.0736092 (rank : 209)	NC score	0.105715 (rank : 909)
Query Neighborhood Hits	457	Target Neighborhood Hits	1058	Shared Neighborhood Hits	160
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

MAT1_HUMAN
θ value	0.0736092 (rank : 210)	NC score	0.116268 (rank : 843)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	59
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MRCKB_MOUSE
θ value	0.0736092 (rank : 211)	NC score	0.157200 (rank : 628)
Query Neighborhood Hits	457	Target Neighborhood Hits	2180	Shared Neighborhood Hits	286
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RUFY2_HUMAN
θ value	0.0736092 (rank : 212)	NC score	0.246401 (rank : 279)
Query Neighborhood Hits	457	Target Neighborhood Hits	1208	Shared Neighborhood Hits	224
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUSC1_MOUSE
θ value	0.0736092 (rank : 213)	NC score	0.251569 (rank : 267)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SM1L2_HUMAN
θ value	0.0736092 (rank : 214)	NC score	0.295784 (rank : 106)
Query Neighborhood Hits	457	Target Neighborhood Hits	1019	Shared Neighborhood Hits	236
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC4_HUMAN
θ value	0.0736092 (rank : 215)	NC score	0.269705 (rank : 201)
Query Neighborhood Hits	457	Target Neighborhood Hits	937	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

ASPP1_MOUSE
θ value	0.0961366 (rank : 216)	NC score	0.258696 (rank : 234)
Query Neighborhood Hits	457	Target Neighborhood Hits	1244	Shared Neighborhood Hits	280
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BCAR1_HUMAN
θ value	0.0961366 (rank : 217)	NC score	0.261358 (rank : 222)
Query Neighborhood Hits	457	Target Neighborhood Hits	554	Shared Neighborhood Hits	149
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	0.0961366 (rank : 218)	NC score	0.264514 (rank : 213)
Query Neighborhood Hits	457	Target Neighborhood Hits	438	Shared Neighborhood Hits	147
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CENPF_HUMAN
θ value	0.0961366 (rank : 219)	NC score	0.289572 (rank : 119)
Query Neighborhood Hits	457	Target Neighborhood Hits	1932	Shared Neighborhood Hits	272
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KIF3B_MOUSE
θ value	0.0961366 (rank : 220)	NC score	0.120179 (rank : 811)
Query Neighborhood Hits	457	Target Neighborhood Hits	533	Shared Neighborhood Hits	154
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

KMHN1_HUMAN
θ value	0.0961366 (rank : 221)	NC score	0.277197 (rank : 175)
Query Neighborhood Hits	457	Target Neighborhood Hits	950	Shared Neighborhood Hits	215
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

LMNA_HUMAN
θ value	0.0961366 (rank : 222)	NC score	0.165429 (rank : 594)
Query Neighborhood Hits	457	Target Neighborhood Hits	653	Shared Neighborhood Hits	183
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

M3K11_HUMAN
θ value	0.0961366 (rank : 223)	NC score	0.114911 (rank : 852)
Query Neighborhood Hits	457	Target Neighborhood Hits	1136	Shared Neighborhood Hits	176
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MRIP_MOUSE
θ value	0.0961366 (rank : 224)	NC score	0.164618 (rank : 600)
Query Neighborhood Hits	457	Target Neighborhood Hits	569	Shared Neighborhood Hits	148
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MYO6_MOUSE
θ value	0.0961366 (rank : 225)	NC score	0.190733 (rank : 504)
Query Neighborhood Hits	457	Target Neighborhood Hits	586	Shared Neighborhood Hits	155
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NOP56_MOUSE
θ value	0.0961366 (rank : 226)	NC score	0.048330 (rank : 1525)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D6Z1, Q3UD45, Q8BVL1, Q8VDT2, Q99LT8, Q9CT15	Gene names	Nol5a, Nop56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

PHF20_MOUSE
θ value	0.0961366 (rank : 227)	NC score	0.094338 (rank : 1015)
Query Neighborhood Hits	457	Target Neighborhood Hits	513	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

SMC2_HUMAN
θ value	0.0961366 (rank : 228)	NC score	0.298056 (rank : 102)
Query Neighborhood Hits	457	Target Neighborhood Hits	1405	Shared Neighborhood Hits	259
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TAF3_HUMAN
θ value	0.0961366 (rank : 229)	NC score	0.098919 (rank : 974)
Query Neighborhood Hits	457	Target Neighborhood Hits	568	Shared Neighborhood Hits	103
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BAIP2_HUMAN
θ value	0.125558 (rank : 230)	NC score	0.178256 (rank : 548)
Query Neighborhood Hits	457	Target Neighborhood Hits	192	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	0.125558 (rank : 231)	NC score	0.182067 (rank : 530)
Query Neighborhood Hits	457	Target Neighborhood Hits	185	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

CCD11_MOUSE
θ value	0.125558 (rank : 232)	NC score	0.246196 (rank : 280)
Query Neighborhood Hits	457	Target Neighborhood Hits	498	Shared Neighborhood Hits	156
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CLC4F_HUMAN
θ value	0.125558 (rank : 233)	NC score	0.216004 (rank : 409)
Query Neighborhood Hits	457	Target Neighborhood Hits	513	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

DDEF2_MOUSE
θ value	0.125558 (rank : 234)	NC score	0.187658 (rank : 516)
Query Neighborhood Hits	457	Target Neighborhood Hits	625	Shared Neighborhood Hits	157
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ERCC4_MOUSE
θ value	0.125558 (rank : 235)	NC score	0.041376 (rank : 1534)
Query Neighborhood Hits	457	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

HMMR_HUMAN
θ value	0.125558 (rank : 236)	NC score	0.279480 (rank : 158)
Query Neighborhood Hits	457	Target Neighborhood Hits	1082	Shared Neighborhood Hits	216
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

K0423_HUMAN
θ value	0.125558 (rank : 237)	NC score	0.042978 (rank : 1531)
Query Neighborhood Hits	457	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

M3K9_HUMAN
θ value	0.125558 (rank : 238)	NC score	0.114731 (rank : 854)
Query Neighborhood Hits	457	Target Neighborhood Hits	1123	Shared Neighborhood Hits	189
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NCF2_HUMAN
θ value	0.125558 (rank : 239)	NC score	0.431297 (rank : 42)
Query Neighborhood Hits	457	Target Neighborhood Hits	229	Shared Neighborhood Hits	154
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

TMF1_HUMAN
θ value	0.125558 (rank : 240)	NC score	0.268312 (rank : 204)
Query Neighborhood Hits	457	Target Neighborhood Hits	987	Shared Neighborhood Hits	209
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

CSK_HUMAN
θ value	0.163984 (rank : 241)	NC score	0.096304 (rank : 999)
Query Neighborhood Hits	457	Target Neighborhood Hits	1009	Shared Neighborhood Hits	130
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	0.163984 (rank : 242)	NC score	0.096520 (rank : 996)
Query Neighborhood Hits	457	Target Neighborhood Hits	1009	Shared Neighborhood Hits	130
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CTRO_MOUSE
θ value	0.163984 (rank : 243)	NC score	0.165054 (rank : 597)
Query Neighborhood Hits	457	Target Neighborhood Hits	2344	Shared Neighborhood Hits	283
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DNJC7_HUMAN
θ value	0.163984 (rank : 244)	NC score	0.039351 (rank : 1536)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	22
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

EFS_HUMAN
θ value	0.163984 (rank : 245)	NC score	0.279232 (rank : 160)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	132
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	0.163984 (rank : 246)	NC score	0.284111 (rank : 134)
Query Neighborhood Hits	457	Target Neighborhood Hits	389	Shared Neighborhood Hits	135
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

KI21A_HUMAN
θ value	0.163984 (rank : 247)	NC score	0.171323 (rank : 569)
Query Neighborhood Hits	457	Target Neighborhood Hits	1543	Shared Neighborhood Hits	238
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KIF5C_MOUSE
θ value	0.163984 (rank : 248)	NC score	0.197791 (rank : 477)
Query Neighborhood Hits	457	Target Neighborhood Hits	1040	Shared Neighborhood Hits	228
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LMNA_MOUSE
θ value	0.163984 (rank : 249)	NC score	0.165346 (rank : 595)
Query Neighborhood Hits	457	Target Neighborhood Hits	661	Shared Neighborhood Hits	185
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

NCK2_HUMAN
θ value	0.163984 (rank : 250)	NC score	0.364596 (rank : 62)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	163
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

RBM25_HUMAN
θ value	0.163984 (rank : 251)	NC score	0.210521 (rank : 433)
Query Neighborhood Hits	457	Target Neighborhood Hits	682	Shared Neighborhood Hits	165
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RRBP1_MOUSE
θ value	0.163984 (rank : 252)	NC score	0.251981 (rank : 264)
Query Neighborhood Hits	457	Target Neighborhood Hits	1650	Shared Neighborhood Hits	246
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

VAV3_HUMAN
θ value	0.163984 (rank : 253)	NC score	0.281193 (rank : 148)
Query Neighborhood Hits	457	Target Neighborhood Hits	398	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	0.163984 (rank : 254)	NC score	0.279222 (rank : 161)
Query Neighborhood Hits	457	Target Neighborhood Hits	404	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

FGR_MOUSE
θ value	0.21417 (rank : 255)	NC score	0.128997 (rank : 765)
Query Neighborhood Hits	457	Target Neighborhood Hits	1069	Shared Neighborhood Hits	165
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

MYH11_MOUSE
θ value	0.21417 (rank : 256)	NC score	0.277364 (rank : 173)
Query Neighborhood Hits	457	Target Neighborhood Hits	1777	Shared Neighborhood Hits	272
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

BPAEA_HUMAN
θ value	0.279714 (rank : 257)	NC score	0.230589 (rank : 347)
Query Neighborhood Hits	457	Target Neighborhood Hits	1369	Shared Neighborhood Hits	224
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CP135_MOUSE
θ value	0.279714 (rank : 258)	NC score	0.287761 (rank : 124)
Query Neighborhood Hits	457	Target Neighborhood Hits	1278	Shared Neighborhood Hits	239
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CROCC_HUMAN
θ value	0.279714 (rank : 259)	NC score	0.251280 (rank : 269)
Query Neighborhood Hits	457	Target Neighborhood Hits	1409	Shared Neighborhood Hits	231
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FLIP1_MOUSE
θ value	0.279714 (rank : 260)	NC score	0.290824 (rank : 117)
Query Neighborhood Hits	457	Target Neighborhood Hits	1176	Shared Neighborhood Hits	230
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

IF2P_HUMAN
θ value	0.279714 (rank : 261)	NC score	0.219285 (rank : 391)
Query Neighborhood Hits	457	Target Neighborhood Hits	889	Shared Neighborhood Hits	188
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IFIT3_MOUSE
θ value	0.279714 (rank : 262)	NC score	0.030177 (rank : 1540)
Query Neighborhood Hits	457	Target Neighborhood Hits	61	Shared Neighborhood Hits	15
SwissProt Accessions	Q64345, Q99L62	Gene names	Ifit3, Garg49, Ifi49
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (Glucocorticoid-attenuated response gene 49 protein) (GARG-49) (IRG2).

JIP2_HUMAN
θ value	0.279714 (rank : 263)	NC score	0.136547 (rank : 724)
Query Neighborhood Hits	457	Target Neighborhood Hits	288	Shared Neighborhood Hits	71
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	0.279714 (rank : 264)	NC score	0.136812 (rank : 723)
Query Neighborhood Hits	457	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KIF3B_HUMAN
θ value	0.279714 (rank : 265)	NC score	0.119176 (rank : 822)
Query Neighborhood Hits	457	Target Neighborhood Hits	540	Shared Neighborhood Hits	154
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

NFH_HUMAN
θ value	0.279714 (rank : 266)	NC score	0.109527 (rank : 883)
Query Neighborhood Hits	457	Target Neighborhood Hits	1242	Shared Neighborhood Hits	199
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF20_HUMAN
θ value	0.279714 (rank : 267)	NC score	0.086988 (rank : 1076)
Query Neighborhood Hits	457	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

TPM3_MOUSE
θ value	0.279714 (rank : 268)	NC score	0.227664 (rank : 362)
Query Neighborhood Hits	457	Target Neighborhood Hits	676	Shared Neighborhood Hits	169
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

BIN1_HUMAN
θ value	0.365318 (rank : 269)	NC score	0.175068 (rank : 554)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	0.365318 (rank : 270)	NC score	0.179060 (rank : 542)
Query Neighborhood Hits	457	Target Neighborhood Hits	283	Shared Neighborhood Hits	103
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BRE1A_HUMAN
θ value	0.365318 (rank : 271)	NC score	0.255031 (rank : 250)
Query Neighborhood Hits	457	Target Neighborhood Hits	1071	Shared Neighborhood Hits	225
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CCD46_HUMAN
θ value	0.365318 (rank : 272)	NC score	0.295881 (rank : 105)
Query Neighborhood Hits	457	Target Neighborhood Hits	1430	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CHCH3_MOUSE
θ value	0.365318 (rank : 273)	NC score	0.122119 (rank : 802)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CJ118_MOUSE
θ value	0.365318 (rank : 274)	NC score	0.271054 (rank : 199)
Query Neighborhood Hits	457	Target Neighborhood Hits	1132	Shared Neighborhood Hits	227
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CT032_HUMAN
θ value	0.365318 (rank : 275)	NC score	0.282447 (rank : 142)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DIAP1_HUMAN
θ value	0.365318 (rank : 276)	NC score	0.116744 (rank : 839)
Query Neighborhood Hits	457	Target Neighborhood Hits	784	Shared Neighborhood Hits	162
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

GRAP1_MOUSE
θ value	0.365318 (rank : 277)	NC score	0.258663 (rank : 235)
Query Neighborhood Hits	457	Target Neighborhood Hits	1234	Shared Neighborhood Hits	238
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HOOK3_HUMAN
θ value	0.365318 (rank : 278)	NC score	0.257188 (rank : 241)
Query Neighborhood Hits	457	Target Neighborhood Hits	1070	Shared Neighborhood Hits	234
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

KIF4A_HUMAN
θ value	0.365318 (rank : 279)	NC score	0.209294 (rank : 438)
Query Neighborhood Hits	457	Target Neighborhood Hits	1159	Shared Neighborhood Hits	225
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

P85B_HUMAN
θ value	0.365318 (rank : 280)	NC score	0.233883 (rank : 325)
Query Neighborhood Hits	457	Target Neighborhood Hits	543	Shared Neighborhood Hits	200
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RABE1_MOUSE
θ value	0.365318 (rank : 281)	NC score	0.277490 (rank : 172)
Query Neighborhood Hits	457	Target Neighborhood Hits	1105	Shared Neighborhood Hits	229
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SMC3_HUMAN
θ value	0.365318 (rank : 282)	NC score	0.275509 (rank : 184)
Query Neighborhood Hits	457	Target Neighborhood Hits	1186	Shared Neighborhood Hits	236
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SRMS_MOUSE
θ value	0.365318 (rank : 283)	NC score	0.076649 (rank : 1183)
Query Neighborhood Hits	457	Target Neighborhood Hits	964	Shared Neighborhood Hits	104
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TPM3_HUMAN
θ value	0.365318 (rank : 284)	NC score	0.227598 (rank : 363)
Query Neighborhood Hits	457	Target Neighborhood Hits	689	Shared Neighborhood Hits	168
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

ASPP1_HUMAN
θ value	0.47712 (rank : 285)	NC score	0.260418 (rank : 226)
Query Neighborhood Hits	457	Target Neighborhood Hits	956	Shared Neighborhood Hits	275
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAZ1A_HUMAN
θ value	0.47712 (rank : 286)	NC score	0.117066 (rank : 834)
Query Neighborhood Hits	457	Target Neighborhood Hits	693	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DMD_HUMAN
θ value	0.47712 (rank : 287)	NC score	0.225095 (rank : 373)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	219
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

KINH_HUMAN
θ value	0.47712 (rank : 288)	NC score	0.226346 (rank : 367)
Query Neighborhood Hits	457	Target Neighborhood Hits	1231	Shared Neighborhood Hits	239
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MACF1_HUMAN
θ value	0.47712 (rank : 289)	NC score	0.215360 (rank : 412)
Query Neighborhood Hits	457	Target Neighborhood Hits	1341	Shared Neighborhood Hits	213
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

P85B_MOUSE
θ value	0.47712 (rank : 290)	NC score	0.229629 (rank : 354)
Query Neighborhood Hits	457	Target Neighborhood Hits	519	Shared Neighborhood Hits	199
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

REN3B_HUMAN
θ value	0.47712 (rank : 291)	NC score	0.195949 (rank : 487)
Query Neighborhood Hits	457	Target Neighborhood Hits	412	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

SAS6_HUMAN
θ value	0.47712 (rank : 292)	NC score	0.257421 (rank : 239)
Query Neighborhood Hits	457	Target Neighborhood Hits	791	Shared Neighborhood Hits	202
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SHLB2_HUMAN
θ value	0.47712 (rank : 293)	NC score	0.213735 (rank : 419)
Query Neighborhood Hits	457	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	0.47712 (rank : 294)	NC score	0.216327 (rank : 407)
Query Neighborhood Hits	457	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

ARI4A_HUMAN
θ value	0.62314 (rank : 295)	NC score	0.137091 (rank : 720)
Query Neighborhood Hits	457	Target Neighborhood Hits	434	Shared Neighborhood Hits	106
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BLK_HUMAN
θ value	0.62314 (rank : 296)	NC score	0.097872 (rank : 984)
Query Neighborhood Hits	457	Target Neighborhood Hits	994	Shared Neighborhood Hits	137
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

DESP_HUMAN
θ value	0.62314 (rank : 297)	NC score	0.279531 (rank : 155)
Query Neighborhood Hits	457	Target Neighborhood Hits	1470	Shared Neighborhood Hits	255
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EP15_HUMAN
θ value	0.62314 (rank : 298)	NC score	0.218665 (rank : 396)
Query Neighborhood Hits	457	Target Neighborhood Hits	1021	Shared Neighborhood Hits	200
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

F107A_HUMAN
θ value	0.62314 (rank : 299)	NC score	0.061620 (rank : 1359)
Query Neighborhood Hits	457	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	O95990, Q96NH4	Gene names	FAM107A, DRR1, TU3A
Domain Architecture
Description	Protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A).

JIP1_MOUSE
θ value	0.62314 (rank : 300)	NC score	0.119012 (rank : 823)
Query Neighborhood Hits	457	Target Neighborhood Hits	259	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

K1C12_HUMAN
θ value	0.62314 (rank : 301)	NC score	0.072357 (rank : 1229)
Query Neighborhood Hits	457	Target Neighborhood Hits	372	Shared Neighborhood Hits	120
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

MACOI_HUMAN
θ value	0.62314 (rank : 302)	NC score	0.265706 (rank : 210)
Query Neighborhood Hits	457	Target Neighborhood Hits	650	Shared Neighborhood Hits	187
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

PEPL_HUMAN
θ value	0.62314 (rank : 303)	NC score	0.255518 (rank : 247)
Query Neighborhood Hits	457	Target Neighborhood Hits	1141	Shared Neighborhood Hits	225
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SMC3_MOUSE
θ value	0.62314 (rank : 304)	NC score	0.274730 (rank : 187)
Query Neighborhood Hits	457	Target Neighborhood Hits	1187	Shared Neighborhood Hits	236
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SNX23_HUMAN
θ value	0.62314 (rank : 305)	NC score	0.178845 (rank : 543)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	193
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ARHG4_HUMAN
θ value	0.813845 (rank : 306)	NC score	0.233195 (rank : 331)
Query Neighborhood Hits	457	Target Neighborhood Hits	242	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

F107B_HUMAN
θ value	0.813845 (rank : 307)	NC score	0.111719 (rank : 871)
Query Neighborhood Hits	457	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

F107B_MOUSE
θ value	0.813845 (rank : 308)	NC score	0.111725 (rank : 870)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

GOGA4_MOUSE
θ value	0.813845 (rank : 309)	NC score	0.281373 (rank : 147)
Query Neighborhood Hits	457	Target Neighborhood Hits	1939	Shared Neighborhood Hits	268
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HTSF1_HUMAN
θ value	0.813845 (rank : 310)	NC score	0.075260 (rank : 1197)
Query Neighborhood Hits	457	Target Neighborhood Hits	408	Shared Neighborhood Hits	76
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

IF5_HUMAN
θ value	0.813845 (rank : 311)	NC score	0.043352 (rank : 1530)
Query Neighborhood Hits	457	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF5_MOUSE
θ value	0.813845 (rank : 312)	NC score	0.042620 (rank : 1532)
Query Neighborhood Hits	457	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

INCE_MOUSE
θ value	0.813845 (rank : 313)	NC score	0.239298 (rank : 303)
Query Neighborhood Hits	457	Target Neighborhood Hits	903	Shared Neighborhood Hits	200
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

JIP1_HUMAN
θ value	0.813845 (rank : 314)	NC score	0.116868 (rank : 837)
Query Neighborhood Hits	457	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LZTS1_MOUSE
θ value	0.813845 (rank : 315)	NC score	0.207659 (rank : 446)
Query Neighborhood Hits	457	Target Neighborhood Hits	540	Shared Neighborhood Hits	157
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MD1L1_MOUSE
θ value	0.813845 (rank : 316)	NC score	0.267441 (rank : 207)
Query Neighborhood Hits	457	Target Neighborhood Hits	1001	Shared Neighborhood Hits	207
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MYH9_HUMAN
θ value	0.813845 (rank : 317)	NC score	0.271527 (rank : 197)
Query Neighborhood Hits	457	Target Neighborhood Hits	1762	Shared Neighborhood Hits	265
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RABE1_HUMAN
θ value	0.813845 (rank : 318)	NC score	0.278832 (rank : 163)
Query Neighborhood Hits	457	Target Neighborhood Hits	1104	Shared Neighborhood Hits	225
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SHAN1_HUMAN
θ value	0.813845 (rank : 319)	NC score	0.115888 (rank : 845)
Query Neighborhood Hits	457	Target Neighborhood Hits	1041	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

UACA_MOUSE
θ value	0.813845 (rank : 320)	NC score	0.253458 (rank : 256)
Query Neighborhood Hits	457	Target Neighborhood Hits	1620	Shared Neighborhood Hits	246
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AP3D1_HUMAN
θ value	1.06291 (rank : 321)	NC score	0.033516 (rank : 1539)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

EVPL_MOUSE
θ value	1.06291 (rank : 322)	NC score	0.244505 (rank : 286)
Query Neighborhood Hits	457	Target Neighborhood Hits	952	Shared Neighborhood Hits	206
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

KINH_MOUSE
θ value	1.06291 (rank : 323)	NC score	0.212963 (rank : 422)
Query Neighborhood Hits	457	Target Neighborhood Hits	1082	Shared Neighborhood Hits	232
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MACOI_MOUSE
θ value	1.06291 (rank : 324)	NC score	0.258871 (rank : 233)
Query Neighborhood Hits	457	Target Neighborhood Hits	620	Shared Neighborhood Hits	180
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

OXR1_HUMAN
θ value	1.06291 (rank : 325)	NC score	0.080477 (rank : 1136)
Query Neighborhood Hits	457	Target Neighborhood Hits	282	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

RBBP6_MOUSE
θ value	1.06291 (rank : 326)	NC score	0.107218 (rank : 900)
Query Neighborhood Hits	457	Target Neighborhood Hits	1014	Shared Neighborhood Hits	117
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SPTA1_HUMAN
θ value	1.06291 (rank : 327)	NC score	0.301235 (rank : 95)
Query Neighborhood Hits	457	Target Neighborhood Hits	748	Shared Neighborhood Hits	302
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TRI22_HUMAN
θ value	1.06291 (rank : 328)	NC score	0.016519 (rank : 1552)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

BRE1A_MOUSE
θ value	1.38821 (rank : 329)	NC score	0.252210 (rank : 262)
Query Neighborhood Hits	457	Target Neighborhood Hits	1025	Shared Neighborhood Hits	224
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

MRIP_HUMAN
θ value	1.38821 (rank : 330)	NC score	0.157808 (rank : 627)
Query Neighborhood Hits	457	Target Neighborhood Hits	578	Shared Neighborhood Hits	142
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

NDE1_HUMAN
θ value	1.38821 (rank : 331)	NC score	0.228826 (rank : 357)
Query Neighborhood Hits	457	Target Neighborhood Hits	823	Shared Neighborhood Hits	201
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NFH_MOUSE
θ value	1.38821 (rank : 332)	NC score	0.087185 (rank : 1073)
Query Neighborhood Hits	457	Target Neighborhood Hits	2247	Shared Neighborhood Hits	226
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PININ_MOUSE
θ value	1.38821 (rank : 333)	NC score	0.178499 (rank : 547)
Query Neighborhood Hits	457	Target Neighborhood Hits	777	Shared Neighborhood Hits	178
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RBBP6_HUMAN
θ value	1.38821 (rank : 334)	NC score	0.116845 (rank : 838)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	139
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

REN3A_HUMAN
θ value	1.38821 (rank : 335)	NC score	0.098970 (rank : 972)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

RENT2_HUMAN
θ value	1.38821 (rank : 336)	NC score	0.169784 (rank : 577)
Query Neighborhood Hits	457	Target Neighborhood Hits	618	Shared Neighborhood Hits	146
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SC15B_HUMAN
θ value	1.38821 (rank : 337)	NC score	0.048217 (rank : 1526)
Query Neighborhood Hits	457	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2D4	Gene names	SEC15L2, KIAA0919, SEC15B
Domain Architecture
Description	Exocyst complex component Sec15B.

SMC4_MOUSE
θ value	1.38821 (rank : 338)	NC score	0.258610 (rank : 236)
Query Neighborhood Hits	457	Target Neighborhood Hits	830	Shared Neighborhood Hits	197
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SPN90_MOUSE
θ value	1.38821 (rank : 339)	NC score	0.167429 (rank : 582)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TEX9_HUMAN
θ value	1.38821 (rank : 340)	NC score	0.250433 (rank : 272)
Query Neighborhood Hits	457	Target Neighborhood Hits	541	Shared Neighborhood Hits	171
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

CARD9_HUMAN
θ value	1.81305 (rank : 341)	NC score	0.250085 (rank : 273)
Query Neighborhood Hits	457	Target Neighborhood Hits	602	Shared Neighborhood Hits	185
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CHD9_HUMAN
θ value	1.81305 (rank : 342)	NC score	0.021470 (rank : 1548)
Query Neighborhood Hits	457	Target Neighborhood Hits	343	Shared Neighborhood Hits	56
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

GCC2_MOUSE
θ value	1.81305 (rank : 343)	NC score	0.285792 (rank : 129)
Query Neighborhood Hits	457	Target Neighborhood Hits	1619	Shared Neighborhood Hits	252
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

IF3A_HUMAN
θ value	1.81305 (rank : 344)	NC score	0.230850 (rank : 342)
Query Neighborhood Hits	457	Target Neighborhood Hits	875	Shared Neighborhood Hits	199
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	1.81305 (rank : 345)	NC score	0.233471 (rank : 328)
Query Neighborhood Hits	457	Target Neighborhood Hits	871	Shared Neighborhood Hits	199
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

LYN_MOUSE
θ value	1.81305 (rank : 346)	NC score	0.103285 (rank : 933)
Query Neighborhood Hits	457	Target Neighborhood Hits	1023	Shared Neighborhood Hits	146
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MIPO1_HUMAN
θ value	1.81305 (rank : 347)	NC score	0.241124 (rank : 296)
Query Neighborhood Hits	457	Target Neighborhood Hits	486	Shared Neighborhood Hits	162
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

NDE1_MOUSE
θ value	1.81305 (rank : 348)	NC score	0.206011 (rank : 452)
Query Neighborhood Hits	457	Target Neighborhood Hits	602	Shared Neighborhood Hits	172
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

NGEF_HUMAN
θ value	1.81305 (rank : 349)	NC score	0.162512 (rank : 613)
Query Neighborhood Hits	457	Target Neighborhood Hits	166	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PCLO_MOUSE
θ value	1.81305 (rank : 350)	NC score	0.054208 (rank : 1463)
Query Neighborhood Hits	457	Target Neighborhood Hits	2275	Shared Neighborhood Hits	167
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PLCB4_HUMAN
θ value	1.81305 (rank : 351)	NC score	0.202940 (rank : 460)
Query Neighborhood Hits	457	Target Neighborhood Hits	658	Shared Neighborhood Hits	188
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

RSF1_HUMAN
θ value	1.81305 (rank : 352)	NC score	0.102252 (rank : 948)
Query Neighborhood Hits	457	Target Neighborhood Hits	539	Shared Neighborhood Hits	105
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SFR12_MOUSE
θ value	1.81305 (rank : 353)	NC score	0.103926 (rank : 926)
Query Neighborhood Hits	457	Target Neighborhood Hits	486	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SIL1_HUMAN
θ value	1.81305 (rank : 354)	NC score	0.046188 (rank : 1528)
Query Neighborhood Hits	457	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H173, Q8N2L3	Gene names	SIL1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP).

SPN90_HUMAN
θ value	1.81305 (rank : 355)	NC score	0.182425 (rank : 528)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPTA2_HUMAN
θ value	1.81305 (rank : 356)	NC score	0.313303 (rank : 81)
Query Neighborhood Hits	457	Target Neighborhood Hits	888	Shared Neighborhood Hits	318
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SYNE1_HUMAN
θ value	1.81305 (rank : 357)	NC score	0.239156 (rank : 304)
Query Neighborhood Hits	457	Target Neighborhood Hits	1484	Shared Neighborhood Hits	235
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
θ value	1.81305 (rank : 358)	NC score	0.230954 (rank : 340)
Query Neighborhood Hits	457	Target Neighborhood Hits	1323	Shared Neighborhood Hits	219
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TEX2_MOUSE
θ value	1.81305 (rank : 359)	NC score	0.022442 (rank : 1547)
Query Neighborhood Hits	457	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ABTAP_MOUSE
θ value	2.36792 (rank : 360)	NC score	0.120326 (rank : 810)
Query Neighborhood Hits	457	Target Neighborhood Hits	381	Shared Neighborhood Hits	101
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CBP_MOUSE
θ value	2.36792 (rank : 361)	NC score	0.018375 (rank : 1550)
Query Neighborhood Hits	457	Target Neighborhood Hits	1051	Shared Neighborhood Hits	46
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CHD1_HUMAN
θ value	2.36792 (rank : 362)	NC score	0.018645 (rank : 1549)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CPXM1_MOUSE
θ value	2.36792 (rank : 363)	NC score	0.005283 (rank : 1559)
Query Neighborhood Hits	457	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

EP400_HUMAN
θ value	2.36792 (rank : 364)	NC score	0.017626 (rank : 1551)
Query Neighborhood Hits	457	Target Neighborhood Hits	556	Shared Neighborhood Hits	36
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

HOOK3_MOUSE
θ value	2.36792 (rank : 365)	NC score	0.255323 (rank : 248)
Query Neighborhood Hits	457	Target Neighborhood Hits	1007	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

JIP4_MOUSE
θ value	2.36792 (rank : 366)	NC score	0.127040 (rank : 777)
Query Neighborhood Hits	457	Target Neighborhood Hits	593	Shared Neighborhood Hits	155
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

MAP2_MOUSE
θ value	2.36792 (rank : 367)	NC score	0.054555 (rank : 1454)
Query Neighborhood Hits	457	Target Neighborhood Hits	342	Shared Neighborhood Hits	59
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MYO10_HUMAN
θ value	2.36792 (rank : 368)	NC score	0.194641 (rank : 496)
Query Neighborhood Hits	457	Target Neighborhood Hits	920	Shared Neighborhood Hits	203
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NEK1_MOUSE
θ value	2.36792 (rank : 369)	NC score	0.037960 (rank : 1537)
Query Neighborhood Hits	457	Target Neighborhood Hits	1311	Shared Neighborhood Hits	150
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

NKTR_HUMAN
θ value	2.36792 (rank : 370)	NC score	0.044726 (rank : 1529)
Query Neighborhood Hits	457	Target Neighborhood Hits	658	Shared Neighborhood Hits	90
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NKTR_MOUSE
θ value	2.36792 (rank : 371)	NC score	0.025086 (rank : 1543)
Query Neighborhood Hits	457	Target Neighborhood Hits	417	Shared Neighborhood Hits	47
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PKN2_MOUSE
θ value	2.36792 (rank : 372)	NC score	0.026167 (rank : 1542)
Query Neighborhood Hits	457	Target Neighborhood Hits	899	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

RIMB1_MOUSE
θ value	2.36792 (rank : 373)	NC score	0.307747 (rank : 88)
Query Neighborhood Hits	457	Target Neighborhood Hits	1376	Shared Neighborhood Hits	332
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TPM1_MOUSE
θ value	2.36792 (rank : 374)	NC score	0.233509 (rank : 327)
Query Neighborhood Hits	457	Target Neighborhood Hits	729	Shared Neighborhood Hits	197
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

BLK_MOUSE
θ value	3.0926 (rank : 375)	NC score	0.094188 (rank : 1017)
Query Neighborhood Hits	457	Target Neighborhood Hits	992	Shared Neighborhood Hits	125
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BRD4_HUMAN
θ value	3.0926 (rank : 376)	NC score	0.058034 (rank : 1403)
Query Neighborhood Hits	457	Target Neighborhood Hits	851	Shared Neighborhood Hits	136
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CASL_HUMAN
θ value	3.0926 (rank : 377)	NC score	0.234025 (rank : 322)
Query Neighborhood Hits	457	Target Neighborhood Hits	259	Shared Neighborhood Hits	134
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	3.0926 (rank : 378)	NC score	0.238045 (rank : 307)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	136
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

FNBP2_HUMAN
θ value	3.0926 (rank : 379)	NC score	0.199607 (rank : 471)
Query Neighborhood Hits	457	Target Neighborhood Hits	432	Shared Neighborhood Hits	204
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

JIP3_MOUSE
θ value	3.0926 (rank : 380)	NC score	0.158884 (rank : 625)
Query Neighborhood Hits	457	Target Neighborhood Hits	759	Shared Neighborhood Hits	183
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

KIF4A_MOUSE
θ value	3.0926 (rank : 381)	NC score	0.196544 (rank : 483)
Query Neighborhood Hits	457	Target Neighborhood Hits	1033	Shared Neighborhood Hits	216
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

LMD1_HUMAN
θ value	3.0926 (rank : 382)	NC score	0.034827 (rank : 1538)
Query Neighborhood Hits	457	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

MPP10_HUMAN
θ value	3.0926 (rank : 383)	NC score	0.141269 (rank : 698)
Query Neighborhood Hits	457	Target Neighborhood Hits	306	Shared Neighborhood Hits	105
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

NGEF_MOUSE
θ value	3.0926 (rank : 384)	NC score	0.164842 (rank : 598)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

SPTA1_MOUSE
θ value	3.0926 (rank : 385)	NC score	0.274680 (rank : 188)
Query Neighborhood Hits	457	Target Neighborhood Hits	675	Shared Neighborhood Hits	275
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

STK31_MOUSE
θ value	3.0926 (rank : 386)	NC score	0.091753 (rank : 1033)
Query Neighborhood Hits	457	Target Neighborhood Hits	474	Shared Neighborhood Hits	91
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

UBP8_HUMAN
θ value	3.0926 (rank : 387)	NC score	0.075026 (rank : 1199)
Query Neighborhood Hits	457	Target Neighborhood Hits	751	Shared Neighborhood Hits	176
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

41_HUMAN
θ value	4.03905 (rank : 388)	NC score	0.023241 (rank : 1546)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

BI2L1_MOUSE
θ value	4.03905 (rank : 389)	NC score	0.143466 (rank : 690)
Query Neighborhood Hits	457	Target Neighborhood Hits	197	Shared Neighborhood Hits	87
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BTK_HUMAN
θ value	4.03905 (rank : 390)	NC score	0.108561 (rank : 889)
Query Neighborhood Hits	457	Target Neighborhood Hits	1026	Shared Neighborhood Hits	163
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

CAD18_HUMAN
θ value	4.03905 (rank : 391)	NC score	-0.002801 (rank : 1564)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q13634	Gene names	CDH18, CDH14
Domain Architecture
Description	Cadherin-18 precursor (Cadherin-14).

CJ118_HUMAN
θ value	4.03905 (rank : 392)	NC score	0.256592 (rank : 243)
Query Neighborhood Hits	457	Target Neighborhood Hits	937	Shared Neighborhood Hits	203
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

FA50B_MOUSE
θ value	4.03905 (rank : 393)	NC score	0.072577 (rank : 1226)
Query Neighborhood Hits	457	Target Neighborhood Hits	186	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTJ8, Q80X84, Q9D993	Gene names	Fam50b, D0H6S2654E, X5l
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

FUT8_HUMAN
θ value	4.03905 (rank : 394)	NC score	0.088180 (rank : 1065)
Query Neighborhood Hits	457	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

JHD3D_MOUSE
θ value	4.03905 (rank : 395)	NC score	0.006017 (rank : 1558)
Query Neighborhood Hits	457	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

RADI_HUMAN
θ value	4.03905 (rank : 396)	NC score	0.149498 (rank : 655)
Query Neighborhood Hits	457	Target Neighborhood Hits	741	Shared Neighborhood Hits	188
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

SDPR_MOUSE
θ value	4.03905 (rank : 397)	NC score	0.173218 (rank : 559)
Query Neighborhood Hits	457	Target Neighborhood Hits	485	Shared Neighborhood Hits	143
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TR150_HUMAN
θ value	4.03905 (rank : 398)	NC score	0.041724 (rank : 1533)
Query Neighborhood Hits	457	Target Neighborhood Hits	313	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

41_MOUSE
θ value	5.27518 (rank : 399)	NC score	0.023770 (rank : 1544)
Query Neighborhood Hits	457	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

BI2L1_HUMAN
θ value	5.27518 (rank : 400)	NC score	0.148477 (rank : 661)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CF152_HUMAN
θ value	5.27518 (rank : 401)	NC score	0.247519 (rank : 276)
Query Neighborhood Hits	457	Target Neighborhood Hits	704	Shared Neighborhood Hits	210
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CN145_MOUSE
θ value	5.27518 (rank : 402)	NC score	0.251850 (rank : 266)
Query Neighborhood Hits	457	Target Neighborhood Hits	916	Shared Neighborhood Hits	203
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

DOT1L_HUMAN
θ value	5.27518 (rank : 403)	NC score	0.066930 (rank : 1284)
Query Neighborhood Hits	457	Target Neighborhood Hits	660	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FUT8_MOUSE
θ value	5.27518 (rank : 404)	NC score	0.105815 (rank : 908)
Query Neighborhood Hits	457	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

IWS1_MOUSE
θ value	5.27518 (rank : 405)	NC score	0.050852 (rank : 1513)
Query Neighborhood Hits	457	Target Neighborhood Hits	1258	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KMHN1_MOUSE
θ value	5.27518 (rank : 406)	NC score	0.275273 (rank : 185)
Query Neighborhood Hits	457	Target Neighborhood Hits	949	Shared Neighborhood Hits	225
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LAMA4_HUMAN
θ value	5.27518 (rank : 407)	NC score	0.131423 (rank : 755)
Query Neighborhood Hits	457	Target Neighborhood Hits	708	Shared Neighborhood Hits	164
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LYN_HUMAN
θ value	5.27518 (rank : 408)	NC score	0.102298 (rank : 946)
Query Neighborhood Hits	457	Target Neighborhood Hits	1022	Shared Neighborhood Hits	144
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LZTS1_HUMAN
θ value	5.27518 (rank : 409)	NC score	0.207278 (rank : 448)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MD1L1_HUMAN
θ value	5.27518 (rank : 410)	NC score	0.255100 (rank : 249)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	205
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

OXR1_MOUSE
θ value	5.27518 (rank : 411)	NC score	0.086840 (rank : 1079)
Query Neighborhood Hits	457	Target Neighborhood Hits	516	Shared Neighborhood Hits	101
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PLCB1_HUMAN
θ value	5.27518 (rank : 412)	NC score	0.143336 (rank : 691)
Query Neighborhood Hits	457	Target Neighborhood Hits	614	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PTK6_MOUSE
θ value	5.27518 (rank : 413)	NC score	0.089812 (rank : 1049)
Query Neighborhood Hits	457	Target Neighborhood Hits	1026	Shared Neighborhood Hits	142
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

STAC3_HUMAN
θ value	5.27518 (rank : 414)	NC score	0.297894 (rank : 103)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	134
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	5.27518 (rank : 415)	NC score	0.299263 (rank : 99)
Query Neighborhood Hits	457	Target Neighborhood Hits	232	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STK10_MOUSE
θ value	5.27518 (rank : 416)	NC score	0.125560 (rank : 785)
Query Neighborhood Hits	457	Target Neighborhood Hits	2132	Shared Neighborhood Hits	269
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TPM1_HUMAN
θ value	5.27518 (rank : 417)	NC score	0.230802 (rank : 345)
Query Neighborhood Hits	457	Target Neighborhood Hits	716	Shared Neighborhood Hits	193
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TTC3_HUMAN
θ value	5.27518 (rank : 418)	NC score	0.166334 (rank : 590)
Query Neighborhood Hits	457	Target Neighborhood Hits	664	Shared Neighborhood Hits	161
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

ANXA6_MOUSE
θ value	6.88961 (rank : 419)	NC score	0.002657 (rank : 1562)
Query Neighborhood Hits	457	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P14824	Gene names	Anxa6, Anx6
Domain Architecture
Description	Annexin A6 (Annexin VI) (Lipocortin VI) (P68) (P70) (Protein III) (Chromobindin-20) (67 kDa calelectrin) (Calphobindin-II) (CPB-II).

CCD45_MOUSE
θ value	6.88961 (rank : 420)	NC score	0.196560 (rank : 482)
Query Neighborhood Hits	457	Target Neighborhood Hits	663	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CEP70_MOUSE
θ value	6.88961 (rank : 421)	NC score	0.213996 (rank : 417)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	161
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CN145_HUMAN
θ value	6.88961 (rank : 422)	NC score	0.271063 (rank : 198)
Query Neighborhood Hits	457	Target Neighborhood Hits	1196	Shared Neighborhood Hits	242
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CR034_MOUSE
θ value	6.88961 (rank : 423)	NC score	0.264126 (rank : 214)
Query Neighborhood Hits	457	Target Neighborhood Hits	643	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CROCC_MOUSE
θ value	6.88961 (rank : 424)	NC score	0.257182 (rank : 242)
Query Neighborhood Hits	457	Target Neighborhood Hits	1460	Shared Neighborhood Hits	240
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DDX23_HUMAN
θ value	6.88961 (rank : 425)	NC score	0.048390 (rank : 1524)
Query Neighborhood Hits	457	Target Neighborhood Hits	486	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DNAI2_HUMAN
θ value	6.88961 (rank : 426)	NC score	0.013725 (rank : 1553)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

GRAP1_HUMAN
θ value	6.88961 (rank : 427)	NC score	0.252300 (rank : 261)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	213
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HOOK2_MOUSE
θ value	6.88961 (rank : 428)	NC score	0.207473 (rank : 447)
Query Neighborhood Hits	457	Target Neighborhood Hits	736	Shared Neighborhood Hits	186
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

ICAL_MOUSE
θ value	6.88961 (rank : 429)	NC score	0.023275 (rank : 1545)
Query Neighborhood Hits	457	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

INCE_HUMAN
θ value	6.88961 (rank : 430)	NC score	0.232275 (rank : 336)
Query Neighborhood Hits	457	Target Neighborhood Hits	978	Shared Neighborhood Hits	201
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MACF1_MOUSE
θ value	6.88961 (rank : 431)	NC score	0.206769 (rank : 449)
Query Neighborhood Hits	457	Target Neighborhood Hits	1313	Shared Neighborhood Hits	207
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

PTK6_HUMAN
θ value	6.88961 (rank : 432)	NC score	0.087195 (rank : 1072)
Query Neighborhood Hits	457	Target Neighborhood Hits	1020	Shared Neighborhood Hits	145
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

RIMB2_HUMAN
θ value	6.88961 (rank : 433)	NC score	0.193132 (rank : 499)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	117
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

S3TC2_MOUSE
θ value	6.88961 (rank : 434)	NC score	0.048061 (rank : 1527)
Query Neighborhood Hits	457	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

TAF3_MOUSE
θ value	6.88961 (rank : 435)	NC score	0.088784 (rank : 1058)
Query Neighborhood Hits	457	Target Neighborhood Hits	463	Shared Neighborhood Hits	98
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ZC313_HUMAN
θ value	6.88961 (rank : 436)	NC score	0.141850 (rank : 694)
Query Neighborhood Hits	457	Target Neighborhood Hits	772	Shared Neighborhood Hits	157
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN198_HUMAN
θ value	6.88961 (rank : 437)	NC score	0.008581 (rank : 1555)
Query Neighborhood Hits	457	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

B4GN4_MOUSE
θ value	8.99809 (rank : 438)	NC score	0.007996 (rank : 1556)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	11
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BICD2_HUMAN
θ value	8.99809 (rank : 439)	NC score	0.233278 (rank : 330)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	202
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BTK_MOUSE
θ value	8.99809 (rank : 440)	NC score	0.103009 (rank : 937)
Query Neighborhood Hits	457	Target Neighborhood Hits	1017	Shared Neighborhood Hits	157
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CCD55_HUMAN
θ value	8.99809 (rank : 441)	NC score	0.092033 (rank : 1030)
Query Neighborhood Hits	457	Target Neighborhood Hits	513	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CEP35_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.182468 (rank : 527)
Query Neighborhood Hits	457	Target Neighborhood Hits	811	Shared Neighborhood Hits	193
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CM003_HUMAN
θ value	8.99809 (rank : 443)	NC score	0.010733 (rank : 1554)
Query Neighborhood Hits	457	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX90, Q5VZV5, Q86WR2, Q8NBG1, Q96D22	Gene names	C13orf3, RAMA1
Domain Architecture	No domain graphic available
Description	Protein C13orf3.

DDX24_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.002090 (rank : 1563)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DEK_HUMAN
θ value	8.99809 (rank : 445)	NC score	0.049549 (rank : 1523)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

EZRI_MOUSE
θ value	8.99809 (rank : 446)	NC score	0.140794 (rank : 700)
Query Neighborhood Hits	457	Target Neighborhood Hits	693	Shared Neighborhood Hits	183
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FKBP5_MOUSE
θ value	8.99809 (rank : 447)	NC score	0.003892 (rank : 1560)
Query Neighborhood Hits	457	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

K2C1B_HUMAN
θ value	8.99809 (rank : 448)	NC score	0.093647 (rank : 1020)
Query Neighborhood Hits	457	Target Neighborhood Hits	542	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

MAP4_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.027011 (rank : 1541)
Query Neighborhood Hits	457	Target Neighborhood Hits	428	Shared Neighborhood Hits	37
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP9_HUMAN
θ value	8.99809 (rank : 450)	NC score	0.163199 (rank : 608)
Query Neighborhood Hits	457	Target Neighborhood Hits	518	Shared Neighborhood Hits	144
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

RHG04_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.178763 (rank : 545)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	152
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

STMN1_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.163931 (rank : 605)
Query Neighborhood Hits	457	Target Neighborhood Hits	554	Shared Neighborhood Hits	169
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

TAOK3_HUMAN
θ value	8.99809 (rank : 453)	NC score	0.095811 (rank : 1005)
Query Neighborhood Hits	457	Target Neighborhood Hits	1494	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TAOK3_MOUSE
θ value	8.99809 (rank : 454)	NC score	0.088602 (rank : 1060)
Query Neighborhood Hits	457	Target Neighborhood Hits	1458	Shared Neighborhood Hits	216
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

THIM_MOUSE
θ value	8.99809 (rank : 455)	NC score	0.003616 (rank : 1561)
Query Neighborhood Hits	457	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWT1, Q8JZR8	Gene names	Acaa2
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Mitochondrial 3-oxoacyl- CoA thiolase).

TMC2_HUMAN
θ value	8.99809 (rank : 456)	NC score	0.007482 (rank : 1557)
Query Neighborhood Hits	457	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TXLNG_HUMAN
θ value	8.99809 (rank : 457)	NC score	0.192691 (rank : 500)
Query Neighborhood Hits	457	Target Neighborhood Hits	568	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

3BP5_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.202161 (rank : 462)
Query Neighborhood Hits	457	Target Neighborhood Hits	375	Shared Neighborhood Hits	143
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.191326 (rank : 502)
Query Neighborhood Hits	457	Target Neighborhood Hits	346	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

A16L1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.088813 (rank : 1057)
Query Neighborhood Hits	457	Target Neighborhood Hits	664	Shared Neighborhood Hits	132
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

A16L1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.101970 (rank : 951)
Query Neighborhood Hits	457	Target Neighborhood Hits	776	Shared Neighborhood Hits	155
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

A20A1_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.124909 (rank : 788)
Query Neighborhood Hits	457	Target Neighborhood Hits	698	Shared Neighborhood Hits	153
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.124596 (rank : 792)
Query Neighborhood Hits	457	Target Neighborhood Hits	716	Shared Neighborhood Hits	151
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.124178 (rank : 795)
Query Neighborhood Hits	457	Target Neighborhood Hits	692	Shared Neighborhood Hits	153
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.128395 (rank : 769)
Query Neighborhood Hits	457	Target Neighborhood Hits	710	Shared Neighborhood Hits	155
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

AAT1_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.106054 (rank : 907)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

ABL1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.081939 (rank : 1124)
Query Neighborhood Hits	457	Target Neighborhood Hits	1220	Shared Neighborhood Hits	130
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.082641 (rank : 1116)
Query Neighborhood Hits	457	Target Neighborhood Hits	1178	Shared Neighborhood Hits	124
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.078244 (rank : 1164)
Query Neighborhood Hits	457	Target Neighborhood Hits	1045	Shared Neighborhood Hits	115
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABTAP_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.108132 (rank : 893)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ACINU_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.092943 (rank : 1023)
Query Neighborhood Hits	457	Target Neighborhood Hits	828	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.105352 (rank : 913)
Query Neighborhood Hits	457	Target Neighborhood Hits	712	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACTN2_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.056605 (rank : 1426)
Query Neighborhood Hits	457	Target Neighborhood Hits	295	Shared Neighborhood Hits	79
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.054012 (rank : 1467)
Query Neighborhood Hits	457	Target Neighborhood Hits	265	Shared Neighborhood Hits	75
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.066260 (rank : 1293)
Query Neighborhood Hits	457	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.068806 (rank : 1259)
Query Neighborhood Hits	457	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ADIP_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.210774 (rank : 431)
Query Neighborhood Hits	457	Target Neighborhood Hits	470	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

ADIP_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.188145 (rank : 513)
Query Neighborhood Hits	457	Target Neighborhood Hits	415	Shared Neighborhood Hits	154
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

AFAD_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.085575 (rank : 1087)
Query Neighborhood Hits	457	Target Neighborhood Hits	689	Shared Neighborhood Hits	135
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AINX_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.082824 (rank : 1113)
Query Neighborhood Hits	457	Target Neighborhood Hits	442	Shared Neighborhood Hits	135
SwissProt Accessions	Q16352, Q9BRC5	Gene names	INA
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

AINX_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.080450 (rank : 1137)
Query Neighborhood Hits	457	Target Neighborhood Hits	448	Shared Neighborhood Hits	138
SwissProt Accessions	P46660, Q61958, Q8VCW5	Gene names	Ina
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

AKA12_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.103919 (rank : 927)
Query Neighborhood Hits	457	Target Neighborhood Hits	825	Shared Neighborhood Hits	127
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AKAP2_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.058687 (rank : 1388)
Query Neighborhood Hits	457	Target Neighborhood Hits	507	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AKAP6_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.113391 (rank : 861)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	71
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

AL2SB_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.182500 (rank : 526)
Query Neighborhood Hits	457	Target Neighborhood Hits	294	Shared Neighborhood Hits	119
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

AMOL1_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.162211 (rank : 615)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL1_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.145651 (rank : 672)
Query Neighborhood Hits	457	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL2_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.170141 (rank : 575)
Query Neighborhood Hits	457	Target Neighborhood Hits	603	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.165074 (rank : 596)
Query Neighborhood Hits	457	Target Neighborhood Hits	591	Shared Neighborhood Hits	157
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AMOT_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.164790 (rank : 599)
Query Neighborhood Hits	457	Target Neighborhood Hits	712	Shared Neighborhood Hits	161
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AMPH_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.162785 (rank : 611)
Query Neighborhood Hits	457	Target Neighborhood Hits	455	Shared Neighborhood Hits	130
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.153675 (rank : 637)
Query Neighborhood Hits	457	Target Neighborhood Hits	291	Shared Neighborhood Hits	118
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

AMRP_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.119623 (rank : 818)
Query Neighborhood Hits	457	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	P55302	Gene names	Lrpap1
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin-binding protein 44) (HBP-44).

AN30A_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.209345 (rank : 437)
Query Neighborhood Hits	457	Target Neighborhood Hits	1119	Shared Neighborhood Hits	218
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANGL3_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.056029 (rank : 1433)
Query Neighborhood Hits	457	Target Neighborhood Hits	306	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ANGP2_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.083397 (rank : 1107)
Query Neighborhood Hits	457	Target Neighborhood Hits	400	Shared Neighborhood Hits	123
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP2_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.083004 (rank : 1112)
Query Neighborhood Hits	457	Target Neighborhood Hits	397	Shared Neighborhood Hits	133
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANLN_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.073232 (rank : 1217)
Query Neighborhood Hits	457	Target Neighborhood Hits	297	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANR11_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.094454 (rank : 1014)
Query Neighborhood Hits	457	Target Neighborhood Hits	1289	Shared Neighborhood Hits	184
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR21_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.098571 (rank : 977)
Query Neighborhood Hits	457	Target Neighborhood Hits	864	Shared Neighborhood Hits	183
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR26_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.235668 (rank : 315)
Query Neighborhood Hits	457	Target Neighborhood Hits	1554	Shared Neighborhood Hits	239
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR35_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.106691 (rank : 904)
Query Neighborhood Hits	457	Target Neighborhood Hits	784	Shared Neighborhood Hits	150
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANR38_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.061765 (rank : 1354)
Query Neighborhood Hits	457	Target Neighborhood Hits	512	Shared Neighborhood Hits	95
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

APC_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.066187 (rank : 1296)
Query Neighborhood Hits	457	Target Neighborhood Hits	603	Shared Neighborhood Hits	108
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.055875 (rank : 1435)
Query Neighborhood Hits	457	Target Neighborhood Hits	441	Shared Neighborhood Hits	86
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APOA1_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.068582 (rank : 1264)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	73
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

APOA1_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.098560 (rank : 978)
Query Neighborhood Hits	457	Target Neighborhood Hits	210	Shared Neighborhood Hits	82
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

APOA4_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.161921 (rank : 616)
Query Neighborhood Hits	457	Target Neighborhood Hits	399	Shared Neighborhood Hits	118
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOA4_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.189505 (rank : 508)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	119
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOB_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.086171 (rank : 1081)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	64
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

APOE_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.086106 (rank : 1082)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	70
SwissProt Accessions	P02649, Q9P2S4	Gene names	APOE
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

APOE_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.163454 (rank : 606)
Query Neighborhood Hits	457	Target Neighborhood Hits	319	Shared Neighborhood Hits	109
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

APS_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.078774 (rank : 1156)
Query Neighborhood Hits	457	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.059287 (rank : 1380)
Query Neighborhood Hits	457	Target Neighborhood Hits	134	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APXL_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.066609 (rank : 1291)
Query Neighborhood Hits	457	Target Neighborhood Hits	553	Shared Neighborhood Hits	77
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARHG1_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.064380 (rank : 1310)
Query Neighborhood Hits	457	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.059905 (rank : 1375)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	27
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.058195 (rank : 1401)
Query Neighborhood Hits	457	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.057348 (rank : 1410)
Query Neighborhood Hits	457	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.084350 (rank : 1097)
Query Neighborhood Hits	457	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.083291 (rank : 1110)
Query Neighborhood Hits	457	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.163193 (rank : 609)
Query Neighborhood Hits	457	Target Neighborhood Hits	185	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG8_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.078200 (rank : 1167)
Query Neighborhood Hits	457	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.083892 (rank : 1102)
Query Neighborhood Hits	457	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.201162 (rank : 467)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	144
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.201280 (rank : 466)
Query Neighborhood Hits	457	Target Neighborhood Hits	234	Shared Neighborhood Hits	141
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGA_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.081959 (rank : 1123)
Query Neighborhood Hits	457	Target Neighborhood Hits	187	Shared Neighborhood Hits	47
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.077615 (rank : 1175)
Query Neighborhood Hits	457	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.065011 (rank : 1303)
Query Neighborhood Hits	457	Target Neighborhood Hits	375	Shared Neighborhood Hits	44
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.070367 (rank : 1244)
Query Neighborhood Hits	457	Target Neighborhood Hits	351	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.067439 (rank : 1277)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.075511 (rank : 1196)
Query Neighborhood Hits	457	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ASPP2_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.252325 (rank : 260)
Query Neighborhood Hits	457	Target Neighborhood Hits	1156	Shared Neighborhood Hits	274
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATAD3_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.072937 (rank : 1221)
Query Neighborhood Hits	457	Target Neighborhood Hits	326	Shared Neighborhood Hits	97
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3B_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.082809 (rank : 1114)
Query Neighborhood Hits	457	Target Neighborhood Hits	340	Shared Neighborhood Hits	100
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATIF1_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.060311 (rank : 1367)
Query Neighborhood Hits	457	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	O35143	Gene names	Atpif1, Atpi, If1
Domain Architecture
Description	ATPase inhibitor, mitochondrial precursor.

ATRIP_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.088458 (rank : 1061)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

ATRIP_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.073879 (rank : 1212)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

ATRX_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.089804 (rank : 1050)
Query Neighborhood Hits	457	Target Neighborhood Hits	682	Shared Neighborhood Hits	135
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

AZI1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.237290 (rank : 309)
Query Neighborhood Hits	457	Target Neighborhood Hits	1000	Shared Neighborhood Hits	209
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.236669 (rank : 312)
Query Neighborhood Hits	457	Target Neighborhood Hits	990	Shared Neighborhood Hits	218
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BAP29_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.148456 (rank : 663)
Query Neighborhood Hits	457	Target Neighborhood Hits	362	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BAP29_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.144892 (rank : 678)
Query Neighborhood Hits	457	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BAP31_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.097740 (rank : 986)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	89
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.092309 (rank : 1027)
Query Neighborhood Hits	457	Target Neighborhood Hits	701	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.108547 (rank : 890)
Query Neighborhood Hits	457	Target Neighborhood Hits	803	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BCAR3_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.056077 (rank : 1431)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	42
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.053687 (rank : 1474)
Query Neighborhood Hits	457	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCN1_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.150236 (rank : 654)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	140
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

BCN1_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.144103 (rank : 683)
Query Neighborhood Hits	457	Target Neighborhood Hits	367	Shared Neighborhood Hits	130
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

BEGIN_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.124674 (rank : 791)
Query Neighborhood Hits	457	Target Neighborhood Hits	454	Shared Neighborhood Hits	135
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BEGIN_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.117232 (rank : 833)
Query Neighborhood Hits	457	Target Neighborhood Hits	383	Shared Neighborhood Hits	134
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BFSP1_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.144246 (rank : 682)
Query Neighborhood Hits	457	Target Neighborhood Hits	508	Shared Neighborhood Hits	152
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

BFSP2_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.088455 (rank : 1062)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	122
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

BFSP2_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.114605 (rank : 857)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	140
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

BICD1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.253611 (rank : 254)
Query Neighborhood Hits	457	Target Neighborhood Hits	844	Shared Neighborhood Hits	207
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.248610 (rank : 275)
Query Neighborhood Hits	457	Target Neighborhood Hits	837	Shared Neighborhood Hits	200
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.235266 (rank : 319)
Query Neighborhood Hits	457	Target Neighborhood Hits	864	Shared Neighborhood Hits	202
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIN3_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.057052 (rank : 1417)
Query Neighborhood Hits	457	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQY0, Q9BVG2, Q9NVY9	Gene names	BIN3
Domain Architecture
Description	Bridging integrator 3.

BIN3_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.111929 (rank : 866)
Query Neighborhood Hits	457	Target Neighborhood Hits	165	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

BMX_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.052850 (rank : 1487)
Query Neighborhood Hits	457	Target Neighborhood Hits	942	Shared Neighborhood Hits	67
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.052455 (rank : 1494)
Query Neighborhood Hits	457	Target Neighborhood Hits	912	Shared Neighborhood Hits	64
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BPA1_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.219098 (rank : 393)
Query Neighborhood Hits	457	Target Neighborhood Hits	1477	Shared Neighborhood Hits	229
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPTF_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.065225 (rank : 1301)
Query Neighborhood Hits	457	Target Neighborhood Hits	786	Shared Neighborhood Hits	125
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRAP_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.171008 (rank : 572)
Query Neighborhood Hits	457	Target Neighborhood Hits	560	Shared Neighborhood Hits	156
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.118664 (rank : 826)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	120
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRD3_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.053174 (rank : 1482)
Query Neighborhood Hits	457	Target Neighborhood Hits	369	Shared Neighborhood Hits	87
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.056948 (rank : 1420)
Query Neighborhood Hits	457	Target Neighborhood Hits	402	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.059662 (rank : 1376)
Query Neighborhood Hits	457	Target Neighborhood Hits	845	Shared Neighborhood Hits	136
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRE1B_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.241724 (rank : 295)
Query Neighborhood Hits	457	Target Neighborhood Hits	1040	Shared Neighborhood Hits	201
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.229789 (rank : 352)
Query Neighborhood Hits	457	Target Neighborhood Hits	970	Shared Neighborhood Hits	192
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BSN_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.075841 (rank : 1191)
Query Neighborhood Hits	457	Target Neighborhood Hits	1537	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.070792 (rank : 1241)
Query Neighborhood Hits	457	Target Neighborhood Hits	2057	Shared Neighborhood Hits	177
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BST2_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.062956 (rank : 1338)
Query Neighborhood Hits	457	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	Q10589, Q53G07	Gene names	BST2
Domain Architecture
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

C102B_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.247267 (rank : 277)
Query Neighborhood Hits	457	Target Neighborhood Hits	542	Shared Neighborhood Hits	159
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

C8AP2_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.084050 (rank : 1100)
Query Neighborhood Hits	457	Target Neighborhood Hits	548	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CA049_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.072740 (rank : 1223)
Query Neighborhood Hits	457	Target Neighborhood Hits	121	Shared Neighborhood Hits	56
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

CA065_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.188002 (rank : 514)
Query Neighborhood Hits	457	Target Neighborhood Hits	469	Shared Neighborhood Hits	147
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CAF1A_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.167028 (rank : 586)
Query Neighborhood Hits	457	Target Neighborhood Hits	750	Shared Neighborhood Hits	169
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.177965 (rank : 549)
Query Neighborhood Hits	457	Target Neighborhood Hits	736	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.243045 (rank : 293)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	196
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CAR10_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.164002 (rank : 603)
Query Neighborhood Hits	457	Target Neighborhood Hits	569	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CAR10_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.125681 (rank : 784)
Query Neighborhood Hits	457	Target Neighborhood Hits	407	Shared Neighborhood Hits	129
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

CAR11_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.218427 (rank : 397)
Query Neighborhood Hits	457	Target Neighborhood Hits	690	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CAR14_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.150661 (rank : 652)
Query Neighborhood Hits	457	Target Neighborhood Hits	449	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CAR14_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.151869 (rank : 645)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	145
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CASC5_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.126937 (rank : 778)
Query Neighborhood Hits	457	Target Neighborhood Hits	376	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CASP_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.252811 (rank : 258)
Query Neighborhood Hits	457	Target Neighborhood Hits	1131	Shared Neighborhood Hits	235
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.253856 (rank : 253)
Query Neighborhood Hits	457	Target Neighborhood Hits	1152	Shared Neighborhood Hits	237
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCAR1_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.122633 (rank : 799)
Query Neighborhood Hits	457	Target Neighborhood Hits	444	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCAR1_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.108330 (rank : 891)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CCD13_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.259096 (rank : 232)
Query Neighborhood Hits	457	Target Neighborhood Hits	721	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD16_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.067717 (rank : 1275)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	70
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

CCD16_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.079890 (rank : 1144)
Query Neighborhood Hits	457	Target Neighborhood Hits	218	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CCD19_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.245914 (rank : 282)
Query Neighborhood Hits	457	Target Neighborhood Hits	639	Shared Neighborhood Hits	179
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.243598 (rank : 289)
Query Neighborhood Hits	457	Target Neighborhood Hits	1228	Shared Neighborhood Hits	231
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.240922 (rank : 298)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD22_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.129189 (rank : 764)
Query Neighborhood Hits	457	Target Neighborhood Hits	242	Shared Neighborhood Hits	96
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CCD22_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.132415 (rank : 750)
Query Neighborhood Hits	457	Target Neighborhood Hits	268	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CCD27_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.211089 (rank : 430)
Query Neighborhood Hits	457	Target Neighborhood Hits	594	Shared Neighborhood Hits	161
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.224029 (rank : 375)
Query Neighborhood Hits	457	Target Neighborhood Hits	461	Shared Neighborhood Hits	143
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD37_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.095701 (rank : 1006)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	92
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CCD37_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.084890 (rank : 1091)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CCD38_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.144687 (rank : 680)
Query Neighborhood Hits	457	Target Neighborhood Hits	287	Shared Neighborhood Hits	118
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CCD38_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.073238 (rank : 1216)
Query Neighborhood Hits	457	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CDN8, Q8CDD6, Q8CDE1	Gene names	Ccdc38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CCD39_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.279500 (rank : 157)
Query Neighborhood Hits	457	Target Neighborhood Hits	868	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.284715 (rank : 133)
Query Neighborhood Hits	457	Target Neighborhood Hits	1026	Shared Neighborhood Hits	221
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.265447 (rank : 211)
Query Neighborhood Hits	457	Target Neighborhood Hits	1139	Shared Neighborhood Hits	229
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.273889 (rank : 191)
Query Neighborhood Hits	457	Target Neighborhood Hits	1399	Shared Neighborhood Hits	250
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.199963 (rank : 469)
Query Neighborhood Hits	457	Target Neighborhood Hits	406	Shared Neighborhood Hits	150
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD42_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.148026 (rank : 665)
Query Neighborhood Hits	457	Target Neighborhood Hits	284	Shared Neighborhood Hits	114
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD45_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.194775 (rank : 495)
Query Neighborhood Hits	457	Target Neighborhood Hits	525	Shared Neighborhood Hits	167
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD50_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.094750 (rank : 1011)
Query Neighborhood Hits	457	Target Neighborhood Hits	237	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD50_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.061040 (rank : 1362)
Query Neighborhood Hits	457	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD55_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.073515 (rank : 1214)
Query Neighborhood Hits	457	Target Neighborhood Hits	519	Shared Neighborhood Hits	90
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD62_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.271749 (rank : 196)
Query Neighborhood Hits	457	Target Neighborhood Hits	631	Shared Neighborhood Hits	185
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.230827 (rank : 343)
Query Neighborhood Hits	457	Target Neighborhood Hits	868	Shared Neighborhood Hits	213
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD91_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.224711 (rank : 374)
Query Neighborhood Hits	457	Target Neighborhood Hits	699	Shared Neighborhood Hits	188
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD93_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.227818 (rank : 360)
Query Neighborhood Hits	457	Target Neighborhood Hits	600	Shared Neighborhood Hits	170
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD93_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.187637 (rank : 517)
Query Neighborhood Hits	457	Target Neighborhood Hits	362	Shared Neighborhood Hits	137
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD94_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.055427 (rank : 1443)
Query Neighborhood Hits	457	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BW85, O75270, Q9H862, Q9NW16	Gene names	CCDC94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

CCD94_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.053274 (rank : 1478)
Query Neighborhood Hits	457	Target Neighborhood Hits	127	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D6J3	Gene names	Ccdc94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

CCD96_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.222173 (rank : 383)
Query Neighborhood Hits	457	Target Neighborhood Hits	595	Shared Neighborhood Hits	155
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.226679 (rank : 366)
Query Neighborhood Hits	457	Target Neighborhood Hits	704	Shared Neighborhood Hits	184
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC3_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.085506 (rank : 1088)
Query Neighborhood Hits	457	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CCDC5_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.098855 (rank : 975)
Query Neighborhood Hits	457	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

CCDC5_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.059062 (rank : 1383)
Query Neighborhood Hits	457	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BHX1, Q3UIH2, Q8R1M1	Gene names	Ccdc5
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5.

CCDC6_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.233318 (rank : 329)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	186
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCDC7_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.159586 (rank : 623)
Query Neighborhood Hits	457	Target Neighborhood Hits	253	Shared Neighborhood Hits	98
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

CCHCR_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.228515 (rank : 358)
Query Neighborhood Hits	457	Target Neighborhood Hits	717	Shared Neighborhood Hits	180
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.245948 (rank : 281)
Query Neighborhood Hits	457	Target Neighborhood Hits	932	Shared Neighborhood Hits	212
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CCNB3_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.102817 (rank : 941)
Query Neighborhood Hits	457	Target Neighborhood Hits	368	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CD008_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.052530 (rank : 1493)
Query Neighborhood Hits	457	Target Neighborhood Hits	330	Shared Neighborhood Hits	65
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CD72_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.077079 (rank : 1179)
Query Neighborhood Hits	457	Target Neighborhood Hits	345	Shared Neighborhood Hits	90
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

CD72_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.072586 (rank : 1225)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	82
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

CDC37_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.154023 (rank : 635)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	155
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDC37_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.124850 (rank : 789)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	133
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDR2_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.193276 (rank : 498)
Query Neighborhood Hits	457	Target Neighborhood Hits	404	Shared Neighborhood Hits	147
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

CDR2_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.214926 (rank : 415)
Query Neighborhood Hits	457	Target Neighborhood Hits	482	Shared Neighborhood Hits	159
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CE152_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.280874 (rank : 150)
Query Neighborhood Hits	457	Target Neighborhood Hits	976	Shared Neighborhood Hits	214
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CENPH_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.229855 (rank : 351)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	144
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CENPH_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.171644 (rank : 565)
Query Neighborhood Hits	457	Target Neighborhood Hits	195	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

CENPJ_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.202482 (rank : 461)
Query Neighborhood Hits	457	Target Neighborhood Hits	721	Shared Neighborhood Hits	197
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CENPK_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.166214 (rank : 591)
Query Neighborhood Hits	457	Target Neighborhood Hits	273	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

CENPK_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.091570 (rank : 1036)
Query Neighborhood Hits	457	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

CENPQ_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.087244 (rank : 1071)
Query Neighborhood Hits	457	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

CENPQ_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.104727 (rank : 917)
Query Neighborhood Hits	457	Target Neighborhood Hits	160	Shared Neighborhood Hits	71
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

CENPU_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.131657 (rank : 754)
Query Neighborhood Hits	457	Target Neighborhood Hits	289	Shared Neighborhood Hits	118
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CEP55_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.229556 (rank : 355)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	165
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.235389 (rank : 317)
Query Neighborhood Hits	457	Target Neighborhood Hits	693	Shared Neighborhood Hits	187
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.208760 (rank : 441)
Query Neighborhood Hits	457	Target Neighborhood Hits	576	Shared Neighborhood Hits	173
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CEP57_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.198315 (rank : 475)
Query Neighborhood Hits	457	Target Neighborhood Hits	580	Shared Neighborhood Hits	174
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP63_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.278831 (rank : 164)
Query Neighborhood Hits	457	Target Neighborhood Hits	1005	Shared Neighborhood Hits	217
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.217925 (rank : 399)
Query Neighborhood Hits	457	Target Neighborhood Hits	432	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CEP72_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.096266 (rank : 1000)
Query Neighborhood Hits	457	Target Neighborhood Hits	374	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CEP72_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.123962 (rank : 796)
Query Neighborhood Hits	457	Target Neighborhood Hits	381	Shared Neighborhood Hits	107
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CF010_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.104110 (rank : 923)
Query Neighborhood Hits	457	Target Neighborhood Hits	329	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CF060_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.275072 (rank : 186)
Query Neighborhood Hits	457	Target Neighborhood Hits	1270	Shared Neighborhood Hits	235
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF118_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.098604 (rank : 976)
Query Neighborhood Hits	457	Target Neighborhood Hits	154	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T5N4, Q8TC11	Gene names	C6orf118
Domain Architecture	No domain graphic available
Description	Protein C6orf118.

CF152_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.208250 (rank : 443)
Query Neighborhood Hits	457	Target Neighborhood Hits	597	Shared Neighborhood Hits	179
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CF182_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.198434 (rank : 474)
Query Neighborhood Hits	457	Target Neighborhood Hits	474	Shared Neighborhood Hits	158
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CF182_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.194837 (rank : 494)
Query Neighborhood Hits	457	Target Neighborhood Hits	551	Shared Neighborhood Hits	155
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CHCH3_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.077026 (rank : 1180)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CHCH6_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.052112 (rank : 1499)
Query Neighborhood Hits	457	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VN4	Gene names	Chchd6
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.

CHIN_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.050804 (rank : 1515)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.052764 (rank : 1488)
Query Neighborhood Hits	457	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.050466 (rank : 1517)
Query Neighborhood Hits	457	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CI039_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.287572 (rank : 126)
Query Neighborhood Hits	457	Target Neighborhood Hits	1171	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.287931 (rank : 123)
Query Neighborhood Hits	457	Target Neighborhood Hits	1088	Shared Neighborhood Hits	235
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.270689 (rank : 200)
Query Neighborhood Hits	457	Target Neighborhood Hits	1432	Shared Neighborhood Hits	249
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CIP1_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.063077 (rank : 1337)
Query Neighborhood Hits	457	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPC3	Gene names	CCNB1IP1, C14orf18, HEI10
Domain Architecture	No domain graphic available
Description	Cyclin-B1-interacting protein 1 (EC 6.3.2.-) (Human enhancer of invasion 10) (E3 ubiquitin-protein ligase HEI10).

CIP4_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.222629 (rank : 380)
Query Neighborhood Hits	457	Target Neighborhood Hits	374	Shared Neighborhood Hits	159
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CIR_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.060053 (rank : 1372)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	60
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CJ068_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.176285 (rank : 552)
Query Neighborhood Hits	457	Target Neighborhood Hits	316	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CK5P2_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.263046 (rank : 217)
Query Neighborhood Hits	457	Target Neighborhood Hits	1433	Shared Neighborhood Hits	257
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.267975 (rank : 206)
Query Neighborhood Hits	457	Target Neighborhood Hits	1151	Shared Neighborhood Hits	232
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.230810 (rank : 344)
Query Neighborhood Hits	457	Target Neighborhood Hits	592	Shared Neighborhood Hits	166
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.238846 (rank : 306)
Query Neighborhood Hits	457	Target Neighborhood Hits	596	Shared Neighborhood Hits	165
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CL025_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.053193 (rank : 1480)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

CLC4F_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.163261 (rank : 607)
Query Neighborhood Hits	457	Target Neighborhood Hits	572	Shared Neighborhood Hits	144
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

CLSPN_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.084602 (rank : 1095)
Query Neighborhood Hits	457	Target Neighborhood Hits	433	Shared Neighborhood Hits	115
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CLUA1_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.111745 (rank : 869)
Query Neighborhood Hits	457	Target Neighborhood Hits	236	Shared Neighborhood Hits	84
SwissProt Accessions	Q96AJ1, O75138, Q65ZA3, Q9H8R4, Q9H8T1	Gene names	CLUAP1, KIAA0643
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CLUA1_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.137744 (rank : 714)
Query Neighborhood Hits	457	Target Neighborhood Hits	261	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CM007_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.107712 (rank : 896)
Query Neighborhood Hits	457	Target Neighborhood Hits	422	Shared Neighborhood Hits	107
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.080592 (rank : 1134)
Query Neighborhood Hits	457	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CN044_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.099011 (rank : 971)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

CN045_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.139726 (rank : 701)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	102
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CN140_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.054482 (rank : 1459)
Query Neighborhood Hits	457	Target Neighborhood Hits	152	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CCG1, Q8CCM8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf140 homolog.

CNOT3_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.068883 (rank : 1258)
Query Neighborhood Hits	457	Target Neighborhood Hits	425	Shared Neighborhood Hits	86
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.070901 (rank : 1239)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNTRB_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.195722 (rank : 489)
Query Neighborhood Hits	457	Target Neighborhood Hits	690	Shared Neighborhood Hits	159
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.214944 (rank : 414)
Query Neighborhood Hits	457	Target Neighborhood Hits	1029	Shared Neighborhood Hits	207
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

COG6_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.052735 (rank : 1489)
Query Neighborhood Hits	457	Target Neighborhood Hits	118	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2V7, Q5T0U1, Q9ULT5	Gene names	COG6, KIAA1134
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

COVA1_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.135276 (rank : 730)
Query Neighborhood Hits	457	Target Neighborhood Hits	416	Shared Neighborhood Hits	120
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

COVA1_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.114162 (rank : 858)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CP135_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.283398 (rank : 138)
Query Neighborhood Hits	457	Target Neighborhood Hits	1290	Shared Neighborhood Hits	240
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.263044 (rank : 218)
Query Neighborhood Hits	457	Target Neighborhood Hits	1805	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP250_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.259688 (rank : 228)
Query Neighborhood Hits	457	Target Neighborhood Hits	1583	Shared Neighborhood Hits	244
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CR034_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.237160 (rank : 310)
Query Neighborhood Hits	457	Target Neighborhood Hits	538	Shared Neighborhood Hits	176
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CRCM_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.217056 (rank : 404)
Query Neighborhood Hits	457	Target Neighborhood Hits	520	Shared Neighborhood Hits	154
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CREB3_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.058426 (rank : 1394)
Query Neighborhood Hits	457	Target Neighborhood Hits	138	Shared Neighborhood Hits	51
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

CRIP1_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.078267 (rank : 1163)
Query Neighborhood Hits	457	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	P50238, Q13628, Q96J34	Gene names	CRIP1, CRIP
Domain Architecture
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP) (Cysteine-rich heart protein) (hCRHP).

CRIP1_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.077663 (rank : 1174)
Query Neighborhood Hits	457	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	P63254, P04006, Q3THF0	Gene names	Crip1, Crip
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP).

CRIP2_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.058221 (rank : 1400)
Query Neighborhood Hits	457	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	P52943	Gene names	CRIP2, CRP2
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Protein ESP1).

CRIP2_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.059582 (rank : 1377)
Query Neighborhood Hits	457	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCT8	Gene names	Crip2, Crp2, Hlp
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Heart LIM protein).

CRIP3_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.054530 (rank : 1456)
Query Neighborhood Hits	457	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Q6R5, Q5T043, Q6Q6R4, Q6Q6R6, Q6Q6R7	Gene names	CRIP3
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Chromosome 6 LIM-only protein) (h6LIMo).

CRIP3_MOUSE
θ value	θ > 10 (rank : 707)	NC score	0.066223 (rank : 1295)
Query Neighborhood Hits	457	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Q6R3, Q91V23, Q91V60	Gene names	Crip3, Tlp
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Thymus LIM protein) (m17TLP).

CROP_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.110682 (rank : 876)
Query Neighborhood Hits	457	Target Neighborhood Hits	402	Shared Neighborhood Hits	112
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.108081 (rank : 894)
Query Neighborhood Hits	457	Target Neighborhood Hits	403	Shared Neighborhood Hits	110
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CS029_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.078145 (rank : 1169)
Query Neighborhood Hits	457	Target Neighborhood Hits	329	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

CT077_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.056473 (rank : 1427)
Query Neighborhood Hits	457	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

CT077_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.055530 (rank : 1439)
Query Neighborhood Hits	457	Target Neighborhood Hits	122	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

CT096_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.195885 (rank : 488)
Query Neighborhood Hits	457	Target Neighborhood Hits	438	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT116_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.108569 (rank : 888)
Query Neighborhood Hits	457	Target Neighborhood Hits	294	Shared Neighborhood Hits	88
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CT116_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.085772 (rank : 1084)
Query Neighborhood Hits	457	Target Neighborhood Hits	268	Shared Neighborhood Hits	68
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CT151_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.072815 (rank : 1222)
Query Neighborhood Hits	457	Target Neighborhood Hits	382	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CT172_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.050258 (rank : 1522)
Query Neighborhood Hits	457	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CYC5, Q9CYF2, Q9DA26	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172 homolog.

CT2NL_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.250710 (rank : 270)
Query Neighborhood Hits	457	Target Neighborhood Hits	1059	Shared Neighborhood Hits	229
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.233858 (rank : 326)
Query Neighborhood Hits	457	Target Neighborhood Hits	902	Shared Neighborhood Hits	214
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CTGE2_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.197255 (rank : 479)
Query Neighborhood Hits	457	Target Neighborhood Hits	594	Shared Neighborhood Hits	170
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CTGE3_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.064427 (rank : 1309)
Query Neighborhood Hits	457	Target Neighborhood Hits	77	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IX95	Gene names	CTAGE3
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 3 (cTAGE-3 protein).

CTGE4_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.128191 (rank : 771)
Query Neighborhood Hits	457	Target Neighborhood Hits	393	Shared Neighborhood Hits	136
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

CTGE5_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.220624 (rank : 390)
Query Neighborhood Hits	457	Target Neighborhood Hits	800	Shared Neighborhood Hits	214
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CTGE5_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.226175 (rank : 369)
Query Neighborhood Hits	457	Target Neighborhood Hits	928	Shared Neighborhood Hits	211
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CTGE6_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.212799 (rank : 423)
Query Neighborhood Hits	457	Target Neighborhood Hits	650	Shared Neighborhood Hits	183
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

CTTB2_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.131359 (rank : 756)
Query Neighborhood Hits	457	Target Neighborhood Hits	1061	Shared Neighborhood Hits	204
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

CU013_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.222139 (rank : 384)
Query Neighborhood Hits	457	Target Neighborhood Hits	405	Shared Neighborhood Hits	146
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CUTL1_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.225805 (rank : 371)
Query Neighborhood Hits	457	Target Neighborhood Hits	1574	Shared Neighborhood Hits	236
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.226270 (rank : 368)
Query Neighborhood Hits	457	Target Neighborhood Hits	1620	Shared Neighborhood Hits	244
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CUTL2_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.124677 (rank : 790)
Query Neighborhood Hits	457	Target Neighborhood Hits	906	Shared Neighborhood Hits	151
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CUTL2_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.116635 (rank : 840)
Query Neighborhood Hits	457	Target Neighborhood Hits	771	Shared Neighborhood Hits	136
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CYLN2_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.260631 (rank : 225)
Query Neighborhood Hits	457	Target Neighborhood Hits	1004	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.258229 (rank : 238)
Query Neighborhood Hits	457	Target Neighborhood Hits	1002	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DAAM1_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.082455 (rank : 1117)
Query Neighborhood Hits	457	Target Neighborhood Hits	483	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM1_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.086918 (rank : 1077)
Query Neighborhood Hits	457	Target Neighborhood Hits	443	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM2_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.075673 (rank : 1195)
Query Neighborhood Hits	457	Target Neighborhood Hits	350	Shared Neighborhood Hits	112
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAAM2_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.070155 (rank : 1247)
Query Neighborhood Hits	457	Target Neighborhood Hits	371	Shared Neighborhood Hits	110
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAB2P_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.054543 (rank : 1455)
Query Neighborhood Hits	457	Target Neighborhood Hits	303	Shared Neighborhood Hits	80
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.055433 (rank : 1442)
Query Neighborhood Hits	457	Target Neighborhood Hits	284	Shared Neighborhood Hits	80
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DAPP1_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.102532 (rank : 944)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 741)	NC score	0.104343 (rank : 920)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DEK_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.051814 (rank : 1503)
Query Neighborhood Hits	457	Target Neighborhood Hits	280	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DESM_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.096419 (rank : 997)
Query Neighborhood Hits	457	Target Neighborhood Hits	495	Shared Neighborhood Hits	138
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

DESM_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.099368 (rank : 969)
Query Neighborhood Hits	457	Target Neighborhood Hits	498	Shared Neighborhood Hits	144
SwissProt Accessions	P31001	Gene names	Des
Domain Architecture
Description	Desmin.

DFFA_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.052594 (rank : 1492)
Query Neighborhood Hits	457	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	O00273, Q96I97, Q9Y6C6	Gene names	DFFA, DFF1, DFF45
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

DHX16_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.052073 (rank : 1500)
Query Neighborhood Hits	457	Target Neighborhood Hits	356	Shared Neighborhood Hits	107
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DIAP1_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.141618 (rank : 695)
Query Neighborhood Hits	457	Target Neighborhood Hits	839	Shared Neighborhood Hits	178
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DIAP2_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.051493 (rank : 1505)
Query Neighborhood Hits	457	Target Neighborhood Hits	342	Shared Neighborhood Hits	92
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DISC1_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.077380 (rank : 1177)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

DJC17_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.067872 (rank : 1271)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NVM6	Gene names	DNAJC17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

DLG5_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.216209 (rank : 408)
Query Neighborhood Hits	457	Target Neighborhood Hits	1088	Shared Neighborhood Hits	224
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMD_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.230772 (rank : 346)
Query Neighborhood Hits	457	Target Neighborhood Hits	1111	Shared Neighborhood Hits	223
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DMN_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.092796 (rank : 1025)
Query Neighborhood Hits	457	Target Neighborhood Hits	690	Shared Neighborhood Hits	158
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

DNJC8_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.084127 (rank : 1099)
Query Neighborhood Hits	457	Target Neighborhood Hits	380	Shared Neighborhood Hits	92
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.088357 (rank : 1064)
Query Neighborhood Hits	457	Target Neighborhood Hits	392	Shared Neighborhood Hits	96
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

DREB_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.151744 (rank : 646)
Query Neighborhood Hits	457	Target Neighborhood Hits	450	Shared Neighborhood Hits	132
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DREB_MOUSE
θ value	θ > 10 (rank : 757)	NC score	0.153938 (rank : 636)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	120
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DTBP1_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.096793 (rank : 994)
Query Neighborhood Hits	457	Target Neighborhood Hits	185	Shared Neighborhood Hits	70
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

DTBP1_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.089182 (rank : 1055)
Query Neighborhood Hits	457	Target Neighborhood Hits	209	Shared Neighborhood Hits	71
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

DTNA_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.057759 (rank : 1407)
Query Neighborhood Hits	457	Target Neighborhood Hits	295	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

DTNB_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.058367 (rank : 1398)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	89
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

DTNB_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.050888 (rank : 1512)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	77
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

DYDC1_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.058390 (rank : 1397)
Query Neighborhood Hits	457	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWB3, Q5QP03, Q5QP04, Q6WNP4, Q6ZU87	Gene names	DYDC1, DPY30D1
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 1 (RSD-9).

DYHC_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.148920 (rank : 656)
Query Neighborhood Hits	457	Target Neighborhood Hits	733	Shared Neighborhood Hits	199
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.148673 (rank : 657)
Query Neighborhood Hits	457	Target Neighborhood Hits	729	Shared Neighborhood Hits	199
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYNA_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.219048 (rank : 394)
Query Neighborhood Hits	457	Target Neighborhood Hits	1194	Shared Neighborhood Hits	216
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.218758 (rank : 395)
Query Neighborhood Hits	457	Target Neighborhood Hits	1084	Shared Neighborhood Hits	210
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

DYXC1_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.060569 (rank : 1363)
Query Neighborhood Hits	457	Target Neighborhood Hits	261	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

DZIP1_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.145705 (rank : 671)
Query Neighborhood Hits	457	Target Neighborhood Hits	675	Shared Neighborhood Hits	118
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

DZIP1_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.122572 (rank : 800)
Query Neighborhood Hits	457	Target Neighborhood Hits	530	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

DZIP3_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.109372 (rank : 884)
Query Neighborhood Hits	457	Target Neighborhood Hits	399	Shared Neighborhood Hits	110
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.111596 (rank : 872)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	119
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ECT2_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.066662 (rank : 1288)
Query Neighborhood Hits	457	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 774)	NC score	0.067978 (rank : 1269)
Query Neighborhood Hits	457	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EM55_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.058039 (rank : 1402)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.055106 (rank : 1447)
Query Neighborhood Hits	457	Target Neighborhood Hits	221	Shared Neighborhood Hits	73
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

EMIL2_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.138645 (rank : 710)
Query Neighborhood Hits	457	Target Neighborhood Hits	573	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EMIL2_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.099404 (rank : 968)
Query Neighborhood Hits	457	Target Neighborhood Hits	485	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

EMIL3_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.081400 (rank : 1130)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

EMIL3_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.087181 (rank : 1074)
Query Neighborhood Hits	457	Target Neighborhood Hits	240	Shared Neighborhood Hits	86
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

ENAH_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.128317 (rank : 770)
Query Neighborhood Hits	457	Target Neighborhood Hits	784	Shared Neighborhood Hits	165
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.078146 (rank : 1168)
Query Neighborhood Hits	457	Target Neighborhood Hits	919	Shared Neighborhood Hits	136
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP15R_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.233985 (rank : 323)
Query Neighborhood Hits	457	Target Neighborhood Hits	1083	Shared Neighborhood Hits	215
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 784)	NC score	0.229466 (rank : 356)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	224
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EPS8_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.101904 (rank : 953)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	91
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.106400 (rank : 906)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	106
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ERC2_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.292436 (rank : 112)
Query Neighborhood Hits	457	Target Neighborhood Hits	1156	Shared Neighborhood Hits	231
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ES8L1_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.099459 (rank : 967)
Query Neighborhood Hits	457	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L1_MOUSE
θ value	θ > 10 (rank : 789)	NC score	0.091146 (rank : 1040)
Query Neighborhood Hits	457	Target Neighborhood Hits	143	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.122689 (rank : 798)
Query Neighborhood Hits	457	Target Neighborhood Hits	193	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 791)	NC score	0.119485 (rank : 819)
Query Neighborhood Hits	457	Target Neighborhood Hits	169	Shared Neighborhood Hits	110
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.141607 (rank : 696)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	107
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L3_MOUSE
θ value	θ > 10 (rank : 793)	NC score	0.158359 (rank : 626)
Query Neighborhood Hits	457	Target Neighborhood Hits	168	Shared Neighborhood Hits	118
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ESCO1_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.081797 (rank : 1126)
Query Neighborhood Hits	457	Target Neighborhood Hits	361	Shared Neighborhood Hits	88
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

EVPL_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.244858 (rank : 285)
Query Neighborhood Hits	457	Target Neighborhood Hits	895	Shared Neighborhood Hits	208
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EXOC1_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.079474 (rank : 1149)
Query Neighborhood Hits	457	Target Neighborhood Hits	183	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

EXOC1_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.078232 (rank : 1165)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R3S6	Gene names	Exoc1, Sec3, Sec3l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

EXOC5_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.073621 (rank : 1213)
Query Neighborhood Hits	457	Target Neighborhood Hits	194	Shared Neighborhood Hits	78
SwissProt Accessions	O00471	Gene names	EXOC5, SEC10, SEC10L1
Domain Architecture
Description	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10).

EXOC5_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.072386 (rank : 1228)
Query Neighborhood Hits	457	Target Neighborhood Hits	194	Shared Neighborhood Hits	75
SwissProt Accessions	Q3TPX4	Gene names	Exoc5, Sec10l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 5 (Exocyst complex component Sec10).

EZRI_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.137364 (rank : 717)
Query Neighborhood Hits	457	Target Neighborhood Hits	663	Shared Neighborhood Hits	175
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FA44A_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.060428 (rank : 1366)
Query Neighborhood Hits	457	Target Neighborhood Hits	280	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

FA50A_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.119421 (rank : 821)
Query Neighborhood Hits	457	Target Neighborhood Hits	264	Shared Neighborhood Hits	100
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

FA50A_MOUSE
θ value	θ > 10 (rank : 803)	NC score	0.137992 (rank : 713)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

FA76B_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.055865 (rank : 1436)
Query Neighborhood Hits	457	Target Neighborhood Hits	184	Shared Neighborhood Hits	66
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FA76B_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.053042 (rank : 1485)
Query Neighborhood Hits	457	Target Neighborhood Hits	181	Shared Neighborhood Hits	65
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FARP2_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.050259 (rank : 1521)
Query Neighborhood Hits	457	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.053729 (rank : 1473)
Query Neighborhood Hits	457	Target Neighborhood Hits	209	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FBX28_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.055978 (rank : 1434)
Query Neighborhood Hits	457	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

FBX41_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.099627 (rank : 964)
Query Neighborhood Hits	457	Target Neighborhood Hits	475	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.103962 (rank : 924)
Query Neighborhood Hits	457	Target Neighborhood Hits	430	Shared Neighborhood Hits	110
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FCER2_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.050903 (rank : 1511)
Query Neighborhood Hits	457	Target Neighborhood Hits	392	Shared Neighborhood Hits	103
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

FER_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.089968 (rank : 1047)
Query Neighborhood Hits	457	Target Neighborhood Hits	1278	Shared Neighborhood Hits	211
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FEZ2_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.050373 (rank : 1519)
Query Neighborhood Hits	457	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

FGD1_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.055447 (rank : 1441)
Query Neighborhood Hits	457	Target Neighborhood Hits	367	Shared Neighborhood Hits	37
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.052913 (rank : 1486)
Query Neighborhood Hits	457	Target Neighborhood Hits	387	Shared Neighborhood Hits	32
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.063411 (rank : 1332)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.063427 (rank : 1331)
Query Neighborhood Hits	457	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.062340 (rank : 1345)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.064173 (rank : 1316)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	28
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.070679 (rank : 1242)
Query Neighborhood Hits	457	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 821)	NC score	0.069782 (rank : 1250)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD6_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.050934 (rank : 1510)
Query Neighborhood Hits	457	Target Neighborhood Hits	237	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.055522 (rank : 1440)
Query Neighborhood Hits	457	Target Neighborhood Hits	282	Shared Neighborhood Hits	36
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FMNL_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.057115 (rank : 1414)
Query Neighborhood Hits	457	Target Neighborhood Hits	428	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FYCO1_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.232350 (rank : 334)
Query Neighborhood Hits	457	Target Neighborhood Hits	1149	Shared Neighborhood Hits	206
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.239391 (rank : 302)
Query Neighborhood Hits	457	Target Neighborhood Hits	1059	Shared Neighborhood Hits	200
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GAS7_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.143995 (rank : 685)
Query Neighborhood Hits	457	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.127406 (rank : 775)
Query Neighborhood Hits	457	Target Neighborhood Hits	259	Shared Neighborhood Hits	93
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS8_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.262878 (rank : 220)
Query Neighborhood Hits	457	Target Neighborhood Hits	819	Shared Neighborhood Hits	211
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.248708 (rank : 274)
Query Neighborhood Hits	457	Target Neighborhood Hits	622	Shared Neighborhood Hits	185
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GBP1_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.083430 (rank : 1105)
Query Neighborhood Hits	457	Target Neighborhood Hits	339	Shared Neighborhood Hits	111
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

GBP1_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.070192 (rank : 1245)
Query Neighborhood Hits	457	Target Neighborhood Hits	302	Shared Neighborhood Hits	91
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

GBP2_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.084473 (rank : 1096)
Query Neighborhood Hits	457	Target Neighborhood Hits	349	Shared Neighborhood Hits	104
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

GBP2_MOUSE
θ value	θ > 10 (rank : 834)	NC score	0.082337 (rank : 1118)
Query Neighborhood Hits	457	Target Neighborhood Hits	323	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

GBP4_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.114704 (rank : 855)
Query Neighborhood Hits	457	Target Neighborhood Hits	484	Shared Neighborhood Hits	129
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

GBP5_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.058026 (rank : 1404)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

GCC1_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.232604 (rank : 332)
Query Neighborhood Hits	457	Target Neighborhood Hits	887	Shared Neighborhood Hits	196
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 838)	NC score	0.230250 (rank : 349)
Query Neighborhood Hits	457	Target Neighborhood Hits	777	Shared Neighborhood Hits	189
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCF_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.054921 (rank : 1452)
Query Neighborhood Hits	457	Target Neighborhood Hits	107	Shared Neighborhood Hits	48
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

GCP60_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.111084 (rank : 874)
Query Neighborhood Hits	457	Target Neighborhood Hits	419	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GCP60_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.101967 (rank : 952)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GEMI_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.063368 (rank : 1333)
Query Neighborhood Hits	457	Target Neighborhood Hits	192	Shared Neighborhood Hits	51
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

GEMI_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.075233 (rank : 1198)
Query Neighborhood Hits	457	Target Neighborhood Hits	163	Shared Neighborhood Hits	58
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

GFAP_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.133060 (rank : 745)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	184
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GFAP_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.131335 (rank : 757)
Query Neighborhood Hits	457	Target Neighborhood Hits	725	Shared Neighborhood Hits	190
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GIMA4_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.058000 (rank : 1405)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

GLE1_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.152494 (rank : 642)
Query Neighborhood Hits	457	Target Neighborhood Hits	445	Shared Neighborhood Hits	136
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

GLE1_MOUSE
θ value	θ > 10 (rank : 848)	NC score	0.151707 (rank : 647)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

GLU2B_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.070444 (rank : 1243)
Query Neighborhood Hits	457	Target Neighborhood Hits	377	Shared Neighborhood Hits	79
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.066771 (rank : 1287)
Query Neighborhood Hits	457	Target Neighborhood Hits	357	Shared Neighborhood Hits	79
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GNRP_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.067252 (rank : 1280)
Query Neighborhood Hits	457	Target Neighborhood Hits	239	Shared Neighborhood Hits	53
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 852)	NC score	0.059257 (rank : 1381)
Query Neighborhood Hits	457	Target Neighborhood Hits	191	Shared Neighborhood Hits	36
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GO45_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.115653 (rank : 847)
Query Neighborhood Hits	457	Target Neighborhood Hits	189	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H2G9, O15298, Q5T531, Q9GZX4	Gene names	BLZF1, JEM1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor).

GO45_MOUSE
θ value	θ > 10 (rank : 854)	NC score	0.053190 (rank : 1481)
Query Neighborhood Hits	457	Target Neighborhood Hits	139	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

GOG8A_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.206124 (rank : 451)
Query Neighborhood Hits	457	Target Neighborhood Hits	635	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.255771 (rank : 245)
Query Neighborhood Hits	457	Target Neighborhood Hits	1222	Shared Neighborhood Hits	228
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA1_MOUSE
θ value	θ > 10 (rank : 857)	NC score	0.254570 (rank : 252)
Query Neighborhood Hits	457	Target Neighborhood Hits	994	Shared Neighborhood Hits	213
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.230009 (rank : 350)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	186
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	θ > 10 (rank : 859)	NC score	0.252445 (rank : 259)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	203
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.262904 (rank : 219)
Query Neighborhood Hits	457	Target Neighborhood Hits	1317	Shared Neighborhood Hits	230
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.267996 (rank : 205)
Query Neighborhood Hits	457	Target Neighborhood Hits	1437	Shared Neighborhood Hits	237
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA6_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.239650 (rank : 300)
Query Neighborhood Hits	457	Target Neighborhood Hits	1007	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOPC_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.063343 (rank : 1334)
Query Neighborhood Hits	457	Target Neighborhood Hits	377	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GP73_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.155596 (rank : 630)
Query Neighborhood Hits	457	Target Neighborhood Hits	309	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GP73_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.180579 (rank : 539)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	144
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GPS2_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.094971 (rank : 1009)
Query Neighborhood Hits	457	Target Neighborhood Hits	459	Shared Neighborhood Hits	95
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GRB10_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.060535 (rank : 1364)
Query Neighborhood Hits	457	Target Neighborhood Hits	147	Shared Neighborhood Hits	44
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.062219 (rank : 1346)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	46
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.079296 (rank : 1153)
Query Neighborhood Hits	457	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.080880 (rank : 1133)
Query Neighborhood Hits	457	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.063543 (rank : 1329)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	48
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.070854 (rank : 1240)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

HAP1_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.187334 (rank : 518)
Query Neighborhood Hits	457	Target Neighborhood Hits	606	Shared Neighborhood Hits	177
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HAP1_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.138724 (rank : 709)
Query Neighborhood Hits	457	Target Neighborhood Hits	388	Shared Neighborhood Hits	114
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HAPIP_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.133657 (rank : 741)
Query Neighborhood Hits	457	Target Neighborhood Hits	350	Shared Neighborhood Hits	111
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HC127_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.168140 (rank : 580)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	θ > 10 (rank : 877)	NC score	0.168140 (rank : 581)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	111
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

HGS_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.052657 (rank : 1491)
Query Neighborhood Hits	457	Target Neighborhood Hits	517	Shared Neighborhood Hits	69
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.051401 (rank : 1507)
Query Neighborhood Hits	457	Target Neighborhood Hits	589	Shared Neighborhood Hits	69
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HIP1R_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.205790 (rank : 453)
Query Neighborhood Hits	457	Target Neighborhood Hits	809	Shared Neighborhood Hits	195
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 881)	NC score	0.222719 (rank : 379)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	207
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.227135 (rank : 364)
Query Neighborhood Hits	457	Target Neighborhood Hits	1016	Shared Neighborhood Hits	219
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HIRP3_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.064037 (rank : 1321)
Query Neighborhood Hits	457	Target Neighborhood Hits	323	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HM20A_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.074491 (rank : 1205)
Query Neighborhood Hits	457	Target Neighborhood Hits	343	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.076338 (rank : 1185)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	103
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

HMMR_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.280862 (rank : 151)
Query Neighborhood Hits	457	Target Neighborhood Hits	1178	Shared Neighborhood Hits	234
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME1_HUMAN
θ value	θ > 10 (rank : 887)	NC score	0.165547 (rank : 592)
Query Neighborhood Hits	457	Target Neighborhood Hits	564	Shared Neighborhood Hits	157
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

HOME1_MOUSE
θ value	θ > 10 (rank : 888)	NC score	0.171410 (rank : 567)
Query Neighborhood Hits	457	Target Neighborhood Hits	630	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

HOME2_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.181789 (rank : 533)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

HOME2_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.227743 (rank : 361)
Query Neighborhood Hits	457	Target Neighborhood Hits	882	Shared Neighborhood Hits	222
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOME3_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.078557 (rank : 1160)
Query Neighborhood Hits	457	Target Neighborhood Hits	275	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_MOUSE
θ value	θ > 10 (rank : 892)	NC score	0.085677 (rank : 1086)
Query Neighborhood Hits	457	Target Neighborhood Hits	316	Shared Neighborhood Hits	104
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOOK1_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.236794 (rank : 311)
Query Neighborhood Hits	457	Target Neighborhood Hits	942	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.236260 (rank : 313)
Query Neighborhood Hits	457	Target Neighborhood Hits	910	Shared Neighborhood Hits	202
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.204704 (rank : 455)
Query Neighborhood Hits	457	Target Neighborhood Hits	714	Shared Neighborhood Hits	183
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HSF2B_HUMAN
θ value	θ > 10 (rank : 896)	NC score	0.063777 (rank : 1324)
Query Neighborhood Hits	457	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

HSH2D_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.075775 (rank : 1194)
Query Neighborhood Hits	457	Target Neighborhood Hits	159	Shared Neighborhood Hits	42
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IDLC_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.148282 (rank : 664)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	127
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.138926 (rank : 708)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

IFT74_HUMAN
θ value	θ > 10 (rank : 900)	NC score	0.275710 (rank : 183)
Query Neighborhood Hits	457	Target Neighborhood Hits	949	Shared Neighborhood Hits	216
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 901)	NC score	0.259587 (rank : 229)
Query Neighborhood Hits	457	Target Neighborhood Hits	939	Shared Neighborhood Hits	211
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.257195 (rank : 240)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	204
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 903)	NC score	0.268444 (rank : 202)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	216
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IMMT_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.178766 (rank : 544)
Query Neighborhood Hits	457	Target Neighborhood Hits	494	Shared Neighborhood Hits	157
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

IMMT_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.132973 (rank : 746)
Query Neighborhood Hits	457	Target Neighborhood Hits	326	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

ING3_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.054318 (rank : 1461)
Query Neighborhood Hits	457	Target Neighborhood Hits	178	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	θ > 10 (rank : 907)	NC score	0.056945 (rank : 1421)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

INVO_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.221336 (rank : 386)
Query Neighborhood Hits	457	Target Neighborhood Hits	636	Shared Neighborhood Hits	149
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.134397 (rank : 736)
Query Neighborhood Hits	457	Target Neighborhood Hits	474	Shared Neighborhood Hits	116
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

IQGA1_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.081048 (rank : 1132)
Query Neighborhood Hits	457	Target Neighborhood Hits	250	Shared Neighborhood Hits	91
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

IQGA1_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.066612 (rank : 1290)
Query Neighborhood Hits	457	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

ITK_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.075775 (rank : 1193)
Query Neighborhood Hits	457	Target Neighborhood Hits	1016	Shared Neighborhood Hits	130
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

IWS1_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.058464 (rank : 1393)
Query Neighborhood Hits	457	Target Neighborhood Hits	1241	Shared Neighborhood Hits	116
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JIP4_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.131169 (rank : 758)
Query Neighborhood Hits	457	Target Neighborhood Hits	585	Shared Neighborhood Hits	152
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

K0494_HUMAN
θ value	θ > 10 (rank : 915)	NC score	0.171647 (rank : 564)
Query Neighborhood Hits	457	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0494_MOUSE
θ value	θ > 10 (rank : 916)	NC score	0.165545 (rank : 593)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0552_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.182373 (rank : 529)
Query Neighborhood Hits	457	Target Neighborhood Hits	442	Shared Neighborhood Hits	133
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

K0555_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.276128 (rank : 180)
Query Neighborhood Hits	457	Target Neighborhood Hits	880	Shared Neighborhood Hits	222
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

K0586_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.130827 (rank : 761)
Query Neighborhood Hits	457	Target Neighborhood Hits	311	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

K0831_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.106812 (rank : 901)
Query Neighborhood Hits	457	Target Neighborhood Hits	203	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

K0831_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.123447 (rank : 797)
Query Neighborhood Hits	457	Target Neighborhood Hits	277	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

K1377_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.057235 (rank : 1412)
Query Neighborhood Hits	457	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2H0, Q4G0U6	Gene names	KIAA1377
Domain Architecture	No domain graphic available
Description	Protein KIAA1377.

K1914_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.074260 (rank : 1207)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1914_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.054201 (rank : 1464)
Query Neighborhood Hits	457	Target Neighborhood Hits	216	Shared Neighborhood Hits	50
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1C10_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.102718 (rank : 942)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	156
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

K1C10_MOUSE
θ value	θ > 10 (rank : 926)	NC score	0.090140 (rank : 1044)
Query Neighborhood Hits	457	Target Neighborhood Hits	466	Shared Neighborhood Hits	141
SwissProt Accessions	P02535, P08731, Q8BUX3, Q8BV09, Q8BVU3, Q9CXH6, Q9JKB4	Gene names	Krt10, Krt1-10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) (56 kDa cytokeratin) (Keratin, type I cytoskeletal 59 kDa).

K1C12_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.076106 (rank : 1188)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	127
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

K1C13_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.077161 (rank : 1178)
Query Neighborhood Hits	457	Target Neighborhood Hits	386	Shared Neighborhood Hits	127
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

K1C13_MOUSE
θ value	θ > 10 (rank : 929)	NC score	0.080157 (rank : 1139)
Query Neighborhood Hits	457	Target Neighborhood Hits	410	Shared Neighborhood Hits	133
SwissProt Accessions	P08730, Q3V176, Q6PAI1	Gene names	Krt13, Krt1-13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13) (47 kDa cytokeratin).

K1C14_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.098935 (rank : 973)
Query Neighborhood Hits	457	Target Neighborhood Hits	491	Shared Neighborhood Hits	157
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

K1C14_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.104753 (rank : 916)
Query Neighborhood Hits	457	Target Neighborhood Hits	501	Shared Neighborhood Hits	156
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

K1C15_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.074077 (rank : 1210)
Query Neighborhood Hits	457	Target Neighborhood Hits	367	Shared Neighborhood Hits	120
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

K1C15_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.091654 (rank : 1034)
Query Neighborhood Hits	457	Target Neighborhood Hits	429	Shared Neighborhood Hits	138
SwissProt Accessions	Q61414, Q6PEQ0	Gene names	Krt15, Krt1-15
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

K1C16_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.090989 (rank : 1041)
Query Neighborhood Hits	457	Target Neighborhood Hits	440	Shared Neighborhood Hits	139
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

K1C16_MOUSE
θ value	θ > 10 (rank : 935)	NC score	0.094829 (rank : 1010)
Query Neighborhood Hits	457	Target Neighborhood Hits	444	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Z2K1	Gene names	Krt16, Krt1-16
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

K1C17_HUMAN
θ value	θ > 10 (rank : 936)	NC score	0.106533 (rank : 905)
Query Neighborhood Hits	457	Target Neighborhood Hits	463	Shared Neighborhood Hits	150
SwissProt Accessions	Q04695	Gene names	KRT17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1).

K1C17_MOUSE
θ value	θ > 10 (rank : 937)	NC score	0.102965 (rank : 938)
Query Neighborhood Hits	457	Target Neighborhood Hits	456	Shared Neighborhood Hits	144
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

K1C18_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.102276 (rank : 947)
Query Neighborhood Hits	457	Target Neighborhood Hits	441	Shared Neighborhood Hits	146
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

K1C18_MOUSE
θ value	θ > 10 (rank : 939)	NC score	0.085954 (rank : 1083)
Query Neighborhood Hits	457	Target Neighborhood Hits	386	Shared Neighborhood Hits	132
SwissProt Accessions	P05784, Q61766	Gene names	Krt18, Kerd, Krt1-18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18) (Cytokeratin endo B) (Keratin D).

K1C19_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.061404 (rank : 1361)
Query Neighborhood Hits	457	Target Neighborhood Hits	320	Shared Neighborhood Hits	112
SwissProt Accessions	P08727, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4	Gene names	KRT19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

K1C19_MOUSE
θ value	θ > 10 (rank : 941)	NC score	0.068028 (rank : 1268)
Query Neighborhood Hits	457	Target Neighborhood Hits	358	Shared Neighborhood Hits	115
SwissProt Accessions	P19001	Gene names	Krt19, Krt1-19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

K1C20_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.092650 (rank : 1026)
Query Neighborhood Hits	457	Target Neighborhood Hits	468	Shared Neighborhood Hits	144
SwissProt Accessions	P35900	Gene names	KRT20
Domain Architecture
Description	Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT).

K1C23_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.058643 (rank : 1391)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	107
SwissProt Accessions	Q9C075, Q9NUR6	Gene names	KRT23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

K1C23_MOUSE
θ value	θ > 10 (rank : 944)	NC score	0.079014 (rank : 1154)
Query Neighborhood Hits	457	Target Neighborhood Hits	370	Shared Neighborhood Hits	130
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

K1C9_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.104904 (rank : 915)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	158
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

K1H1_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.083422 (rank : 1106)
Query Neighborhood Hits	457	Target Neighborhood Hits	433	Shared Neighborhood Hits	128
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

K1H1_MOUSE
θ value	θ > 10 (rank : 947)	NC score	0.091643 (rank : 1035)
Query Neighborhood Hits	457	Target Neighborhood Hits	450	Shared Neighborhood Hits	140
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

K1H2_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.103197 (rank : 935)
Query Neighborhood Hits	457	Target Neighborhood Hits	492	Shared Neighborhood Hits	147
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

K1H2_MOUSE
θ value	θ > 10 (rank : 949)	NC score	0.096085 (rank : 1002)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	144
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

K1H4_HUMAN
θ value	θ > 10 (rank : 950)	NC score	0.103568 (rank : 930)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	149
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

K1H5_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.057267 (rank : 1411)
Query Neighborhood Hits	457	Target Neighborhood Hits	362	Shared Neighborhood Hits	100
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

K1H6_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.081486 (rank : 1129)
Query Neighborhood Hits	457	Target Neighborhood Hits	408	Shared Neighborhood Hits	131
SwissProt Accessions	O76013	Gene names	KRTHA6, HHA6, HKA6
Domain Architecture
Description	Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6).

K1H7_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.076069 (rank : 1189)
Query Neighborhood Hits	457	Target Neighborhood Hits	369	Shared Neighborhood Hits	127
SwissProt Accessions	O76014	Gene names	KRTHA7, HHA7, HKA7
Domain Architecture
Description	Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7).

K1H8_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.074665 (rank : 1203)
Query Neighborhood Hits	457	Target Neighborhood Hits	394	Shared Neighborhood Hits	121
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

K1HA_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.110161 (rank : 879)
Query Neighborhood Hits	457	Target Neighborhood Hits	502	Shared Neighborhood Hits	153
SwissProt Accessions	O76009	Gene names	KRTHA3A, HHA3-I, HKA3A
Domain Architecture
Description	Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I).

K1HB_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.090265 (rank : 1043)
Query Neighborhood Hits	457	Target Neighborhood Hits	470	Shared Neighborhood Hits	142
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

K22E_HUMAN
θ value	θ > 10 (rank : 957)	NC score	0.103099 (rank : 936)
Query Neighborhood Hits	457	Target Neighborhood Hits	515	Shared Neighborhood Hits	151
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

K22O_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.081933 (rank : 1125)
Query Neighborhood Hits	457	Target Neighborhood Hits	485	Shared Neighborhood Hits	144
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

K2C1B_MOUSE
θ value	θ > 10 (rank : 959)	NC score	0.098439 (rank : 980)
Query Neighborhood Hits	457	Target Neighborhood Hits	503	Shared Neighborhood Hits	159
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

K2C1_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.130751 (rank : 762)
Query Neighborhood Hits	457	Target Neighborhood Hits	624	Shared Neighborhood Hits	176
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

K2C1_MOUSE
θ value	θ > 10 (rank : 961)	NC score	0.097799 (rank : 985)
Query Neighborhood Hits	457	Target Neighborhood Hits	477	Shared Neighborhood Hits	152
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

K2C3_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.079422 (rank : 1151)
Query Neighborhood Hits	457	Target Neighborhood Hits	443	Shared Neighborhood Hits	132
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

K2C4_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.094201 (rank : 1016)
Query Neighborhood Hits	457	Target Neighborhood Hits	471	Shared Neighborhood Hits	155
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

K2C4_MOUSE
θ value	θ > 10 (rank : 964)	NC score	0.105463 (rank : 912)
Query Neighborhood Hits	457	Target Neighborhood Hits	521	Shared Neighborhood Hits	165
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

K2C5_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.103953 (rank : 925)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	159
SwissProt Accessions	P13647, Q6PI71, Q6UBJ0, Q8TA91	Gene names	KRT5
Domain Architecture
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin).

K2C5_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.100807 (rank : 958)
Query Neighborhood Hits	457	Target Neighborhood Hits	505	Shared Neighborhood Hits	162
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

K2C6A_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.101872 (rank : 954)
Query Neighborhood Hits	457	Target Neighborhood Hits	505	Shared Neighborhood Hits	157
SwissProt Accessions	P02538, Q6NT67, Q96CL4	Gene names	KRT6A, K6A
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin).

K2C6A_MOUSE
θ value	θ > 10 (rank : 968)	NC score	0.096342 (rank : 998)
Query Neighborhood Hits	457	Target Neighborhood Hits	481	Shared Neighborhood Hits	152
SwissProt Accessions	P50446, Q9Z332	Gene names	Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin) (Keratin-6 alpha) (mK6-alpha).

K2C6B_HUMAN
θ value	θ > 10 (rank : 969)	NC score	0.105472 (rank : 911)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	160
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6B_MOUSE
θ value	θ > 10 (rank : 970)	NC score	0.098222 (rank : 982)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

K2C6C_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.102149 (rank : 949)
Query Neighborhood Hits	457	Target Neighborhood Hits	503	Shared Neighborhood Hits	157
SwissProt Accessions	P48666	Gene names	KRT6C
Domain Architecture
Description	Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin).

K2C6E_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.104591 (rank : 918)
Query Neighborhood Hits	457	Target Neighborhood Hits	516	Shared Neighborhood Hits	157
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

K2C6G_MOUSE
θ value	θ > 10 (rank : 973)	NC score	0.091928 (rank : 1031)
Query Neighborhood Hits	457	Target Neighborhood Hits	452	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

K2C7_HUMAN
θ value	θ > 10 (rank : 974)	NC score	0.074244 (rank : 1208)
Query Neighborhood Hits	457	Target Neighborhood Hits	369	Shared Neighborhood Hits	124
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

K2C8_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.119817 (rank : 817)
Query Neighborhood Hits	457	Target Neighborhood Hits	593	Shared Neighborhood Hits	166
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

K2C8_MOUSE
θ value	θ > 10 (rank : 976)	NC score	0.118681 (rank : 825)
Query Neighborhood Hits	457	Target Neighborhood Hits	576	Shared Neighborhood Hits	175
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

KI13A_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.064171 (rank : 1317)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

KI13A_MOUSE
θ value	θ > 10 (rank : 978)	NC score	0.074290 (rank : 1206)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	121
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

KI13B_HUMAN
θ value	θ > 10 (rank : 979)	NC score	0.074564 (rank : 1204)
Query Neighborhood Hits	457	Target Neighborhood Hits	492	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

KI18A_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.053795 (rank : 1469)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	73
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

KI20A_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.099653 (rank : 963)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	101
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

KI20A_MOUSE
θ value	θ > 10 (rank : 982)	NC score	0.089561 (rank : 1052)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	95
SwissProt Accessions	P97329, Q542M4	Gene names	Kif20a, Rab6kifl
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (Kinesin-like protein 174).

KI21A_MOUSE
θ value	θ > 10 (rank : 983)	NC score	0.148487 (rank : 659)
Query Neighborhood Hits	457	Target Neighborhood Hits	1317	Shared Neighborhood Hits	224
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KI21B_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.131866 (rank : 753)
Query Neighborhood Hits	457	Target Neighborhood Hits	1017	Shared Neighborhood Hits	189
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KI21B_MOUSE
θ value	θ > 10 (rank : 985)	NC score	0.134528 (rank : 734)
Query Neighborhood Hits	457	Target Neighborhood Hits	997	Shared Neighborhood Hits	184
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KI67_HUMAN
θ value	θ > 10 (rank : 986)	NC score	0.066642 (rank : 1289)
Query Neighborhood Hits	457	Target Neighborhood Hits	581	Shared Neighborhood Hits	81
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIF11_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.160042 (rank : 622)
Query Neighborhood Hits	457	Target Neighborhood Hits	583	Shared Neighborhood Hits	173
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

KIF11_MOUSE
θ value	θ > 10 (rank : 988)	NC score	0.128535 (rank : 767)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	140
SwissProt Accessions	Q6P9P6, Q9Z1J0	Gene names	Kif11
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5).

KIF14_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.128153 (rank : 772)
Query Neighborhood Hits	457	Target Neighborhood Hits	732	Shared Neighborhood Hits	189
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KIF17_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.058658 (rank : 1390)
Query Neighborhood Hits	457	Target Neighborhood Hits	365	Shared Neighborhood Hits	102
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

KIF17_MOUSE
θ value	θ > 10 (rank : 991)	NC score	0.072352 (rank : 1230)
Query Neighborhood Hits	457	Target Neighborhood Hits	452	Shared Neighborhood Hits	112
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

KIF23_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.151343 (rank : 649)
Query Neighborhood Hits	457	Target Neighborhood Hits	618	Shared Neighborhood Hits	178
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

KIF3A_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.133922 (rank : 739)
Query Neighborhood Hits	457	Target Neighborhood Hits	704	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	θ > 10 (rank : 994)	NC score	0.133161 (rank : 744)
Query Neighborhood Hits	457	Target Neighborhood Hits	715	Shared Neighborhood Hits	182
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3C_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.108683 (rank : 887)
Query Neighborhood Hits	457	Target Neighborhood Hits	478	Shared Neighborhood Hits	141
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

KIF3C_MOUSE
θ value	θ > 10 (rank : 996)	NC score	0.108301 (rank : 892)
Query Neighborhood Hits	457	Target Neighborhood Hits	468	Shared Neighborhood Hits	139
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

KIF5A_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.183895 (rank : 524)
Query Neighborhood Hits	457	Target Neighborhood Hits	843	Shared Neighborhood Hits	200
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
θ value	θ > 10 (rank : 998)	NC score	0.182044 (rank : 531)
Query Neighborhood Hits	457	Target Neighborhood Hits	859	Shared Neighborhood Hits	196
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF6_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.072552 (rank : 1227)
Query Neighborhood Hits	457	Target Neighborhood Hits	271	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

KIFC1_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.124313 (rank : 794)
Query Neighborhood Hits	457	Target Neighborhood Hits	545	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

KIFC3_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.139240 (rank : 707)
Query Neighborhood Hits	457	Target Neighborhood Hits	619	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.139280 (rank : 706)
Query Neighborhood Hits	457	Target Neighborhood Hits	571	Shared Neighborhood Hits	163
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KLC1_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.102093 (rank : 950)
Query Neighborhood Hits	457	Target Neighborhood Hits	471	Shared Neighborhood Hits	149
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

KLC1_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.078635 (rank : 1158)
Query Neighborhood Hits	457	Target Neighborhood Hits	357	Shared Neighborhood Hits	123
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

KLC4_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.061949 (rank : 1350)
Query Neighborhood Hits	457	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

KLC4_MOUSE
θ value	θ > 10 (rank : 1006)	NC score	0.063458 (rank : 1330)
Query Neighborhood Hits	457	Target Neighborhood Hits	336	Shared Neighborhood Hits	108
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

KNTC2_HUMAN
θ value	θ > 10 (rank : 1007)	NC score	0.238848 (rank : 305)
Query Neighborhood Hits	457	Target Neighborhood Hits	673	Shared Neighborhood Hits	182
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 1008)	NC score	0.243392 (rank : 291)
Query Neighborhood Hits	457	Target Neighborhood Hits	692	Shared Neighborhood Hits	175
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KRHB1_HUMAN
θ value	θ > 10 (rank : 1009)	NC score	0.077911 (rank : 1170)
Query Neighborhood Hits	457	Target Neighborhood Hits	461	Shared Neighborhood Hits	128
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB3_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.076828 (rank : 1181)
Query Neighborhood Hits	457	Target Neighborhood Hits	438	Shared Neighborhood Hits	130
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

KRHB4_HUMAN
θ value	θ > 10 (rank : 1011)	NC score	0.064334 (rank : 1311)
Query Neighborhood Hits	457	Target Neighborhood Hits	352	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NSB2	Gene names	KRTHB4
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4).

KRHB4_MOUSE
θ value	θ > 10 (rank : 1012)	NC score	0.064192 (rank : 1314)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	119
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

KRHB5_HUMAN
θ value	θ > 10 (rank : 1013)	NC score	0.057050 (rank : 1418)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	106
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

KRHB5_MOUSE
θ value	θ > 10 (rank : 1014)	NC score	0.051839 (rank : 1502)
Query Neighborhood Hits	457	Target Neighborhood Hits	294	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

KRHB6_HUMAN
θ value	θ > 10 (rank : 1015)	NC score	0.078762 (rank : 1157)
Query Neighborhood Hits	457	Target Neighborhood Hits	447	Shared Neighborhood Hits	130
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

KRHB6_MOUSE
θ value	θ > 10 (rank : 1016)	NC score	0.067721 (rank : 1274)
Query Neighborhood Hits	457	Target Neighborhood Hits	413	Shared Neighborhood Hits	125
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

KSYK_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.050324 (rank : 1520)
Query Neighborhood Hits	457	Target Neighborhood Hits	901	Shared Neighborhood Hits	65
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 1018)	NC score	0.050846 (rank : 1514)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	68
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAMA1_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.055655 (rank : 1438)
Query Neighborhood Hits	457	Target Neighborhood Hits	804	Shared Neighborhood Hits	111
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.062520 (rank : 1340)
Query Neighborhood Hits	457	Target Neighborhood Hits	838	Shared Neighborhood Hits	135
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.119925 (rank : 815)
Query Neighborhood Hits	457	Target Neighborhood Hits	1092	Shared Neighborhood Hits	168
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 1022)	NC score	0.141365 (rank : 697)
Query Neighborhood Hits	457	Target Neighborhood Hits	1198	Shared Neighborhood Hits	187
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.125892 (rank : 783)
Query Neighborhood Hits	457	Target Neighborhood Hits	760	Shared Neighborhood Hits	140
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.091557 (rank : 1037)
Query Neighborhood Hits	457	Target Neighborhood Hits	859	Shared Neighborhood Hits	146
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.099242 (rank : 970)
Query Neighborhood Hits	457	Target Neighborhood Hits	584	Shared Neighborhood Hits	129
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 1026)	NC score	0.117755 (rank : 832)
Query Neighborhood Hits	457	Target Neighborhood Hits	1018	Shared Neighborhood Hits	180
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 1027)	NC score	0.091300 (rank : 1038)
Query Neighborhood Hits	457	Target Neighborhood Hits	919	Shared Neighborhood Hits	158
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.115054 (rank : 851)
Query Neighborhood Hits	457	Target Neighborhood Hits	922	Shared Neighborhood Hits	163
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.094980 (rank : 1008)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	159
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.098103 (rank : 983)
Query Neighborhood Hits	457	Target Neighborhood Hits	715	Shared Neighborhood Hits	137
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 1031)	NC score	0.073158 (rank : 1218)
Query Neighborhood Hits	457	Target Neighborhood Hits	614	Shared Neighborhood Hits	108
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LBC_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.061630 (rank : 1358)
Query Neighborhood Hits	457	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LBN_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.143523 (rank : 689)
Query Neighborhood Hits	457	Target Neighborhood Hits	308	Shared Neighborhood Hits	111
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

LBN_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.139519 (rank : 704)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	114
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

LC7L2_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.071917 (rank : 1232)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
θ value	θ > 10 (rank : 1036)	NC score	0.073442 (rank : 1215)
Query Neighborhood Hits	457	Target Neighborhood Hits	244	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

LCK_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.088403 (rank : 1063)
Query Neighborhood Hits	457	Target Neighborhood Hits	987	Shared Neighborhood Hits	118
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.087748 (rank : 1067)
Query Neighborhood Hits	457	Target Neighborhood Hits	981	Shared Neighborhood Hits	118
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LCP2_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.053744 (rank : 1471)
Query Neighborhood Hits	457	Target Neighborhood Hits	531	Shared Neighborhood Hits	62
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 1040)	NC score	0.063167 (rank : 1336)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LETM1_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.159039 (rank : 624)
Query Neighborhood Hits	457	Target Neighborhood Hits	338	Shared Neighborhood Hits	111
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LETM1_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.118241 (rank : 831)
Query Neighborhood Hits	457	Target Neighborhood Hits	240	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LIMA1_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.067840 (rank : 1272)
Query Neighborhood Hits	457	Target Neighborhood Hits	309	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

LIMA1_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.057086 (rank : 1415)
Query Neighborhood Hits	457	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

LIMD2_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.058891 (rank : 1385)
Query Neighborhood Hits	457	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BT23, Q96S91	Gene names	LIMD2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

LIMD2_MOUSE
θ value	θ > 10 (rank : 1046)	NC score	0.060177 (rank : 1369)
Query Neighborhood Hits	457	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGB5	Gene names	Limd2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

LIN1_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.078228 (rank : 1166)
Query Neighborhood Hits	457	Target Neighborhood Hits	187	Shared Neighborhood Hits	74
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

LIPA1_HUMAN
θ value	θ > 10 (rank : 1048)	NC score	0.232512 (rank : 333)
Query Neighborhood Hits	457	Target Neighborhood Hits	1294	Shared Neighborhood Hits	240
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPA2_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.225886 (rank : 370)
Query Neighborhood Hits	457	Target Neighborhood Hits	1044	Shared Neighborhood Hits	221
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.231950 (rank : 338)
Query Neighborhood Hits	457	Target Neighborhood Hits	1282	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA3_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.191155 (rank : 503)
Query Neighborhood Hits	457	Target Neighborhood Hits	828	Shared Neighborhood Hits	188
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.162841 (rank : 610)
Query Neighborhood Hits	457	Target Neighborhood Hits	636	Shared Neighborhood Hits	161
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB2_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.182912 (rank : 525)
Query Neighborhood Hits	457	Target Neighborhood Hits	599	Shared Neighborhood Hits	158
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LIPB2_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.180817 (rank : 538)
Query Neighborhood Hits	457	Target Neighborhood Hits	570	Shared Neighborhood Hits	157
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LMNB1_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.171612 (rank : 566)
Query Neighborhood Hits	457	Target Neighborhood Hits	714	Shared Neighborhood Hits	191
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LMNB1_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.171973 (rank : 562)
Query Neighborhood Hits	457	Target Neighborhood Hits	719	Shared Neighborhood Hits	191
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

LMNB2_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.169983 (rank : 576)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	187
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

LMNB2_MOUSE
θ value	θ > 10 (rank : 1058)	NC score	0.161010 (rank : 619)
Query Neighborhood Hits	457	Target Neighborhood Hits	674	Shared Neighborhood Hits	186
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LMO7_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.088749 (rank : 1059)
Query Neighborhood Hits	457	Target Neighborhood Hits	507	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LNK_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.068805 (rank : 1260)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 1061)	NC score	0.068311 (rank : 1267)
Query Neighborhood Hits	457	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LRC27_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.091167 (rank : 1039)
Query Neighborhood Hits	457	Target Neighborhood Hits	710	Shared Neighborhood Hits	127
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

LRC45_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.233969 (rank : 324)
Query Neighborhood Hits	457	Target Neighborhood Hits	933	Shared Neighborhood Hits	204
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 1064)	NC score	0.243996 (rank : 287)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	210
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC48_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.064592 (rank : 1307)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

LRMP_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.062085 (rank : 1347)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

LRRF1_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.181470 (rank : 535)
Query Neighborhood Hits	457	Target Neighborhood Hits	625	Shared Neighborhood Hits	164
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LRRF1_MOUSE
θ value	θ > 10 (rank : 1068)	NC score	0.095834 (rank : 1004)
Query Neighborhood Hits	457	Target Neighborhood Hits	440	Shared Neighborhood Hits	106
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

LRRF2_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.260652 (rank : 224)
Query Neighborhood Hits	457	Target Neighborhood Hits	791	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRRF2_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.256523 (rank : 244)
Query Neighborhood Hits	457	Target Neighborhood Hits	556	Shared Neighborhood Hits	173
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRSM1_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.146604 (rank : 668)
Query Neighborhood Hits	457	Target Neighborhood Hits	1078	Shared Neighborhood Hits	187
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRSM1_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.125349 (rank : 786)
Query Neighborhood Hits	457	Target Neighborhood Hits	874	Shared Neighborhood Hits	160
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

LZTS2_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.166999 (rank : 587)
Query Neighborhood Hits	457	Target Neighborhood Hits	427	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

LZTS2_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.151208 (rank : 651)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	121
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

M4K4_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.072703 (rank : 1224)
Query Neighborhood Hits	457	Target Neighborhood Hits	1589	Shared Neighborhood Hits	206
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	θ > 10 (rank : 1076)	NC score	0.071008 (rank : 1238)
Query Neighborhood Hits	457	Target Neighborhood Hits	1560	Shared Neighborhood Hits	201
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MACF4_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.229777 (rank : 353)
Query Neighborhood Hits	457	Target Neighborhood Hits	1321	Shared Neighborhood Hits	217
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MAP1A_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.209388 (rank : 436)
Query Neighborhood Hits	457	Target Neighborhood Hits	1626	Shared Neighborhood Hits	231
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP9_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.135774 (rank : 726)
Query Neighborhood Hits	457	Target Neighborhood Hits	529	Shared Neighborhood Hits	127
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAT1_MOUSE
θ value	θ > 10 (rank : 1080)	NC score	0.093478 (rank : 1021)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	69
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MATK_HUMAN
θ value	θ > 10 (rank : 1081)	NC score	0.062012 (rank : 1349)
Query Neighborhood Hits	457	Target Neighborhood Hits	954	Shared Neighborhood Hits	80
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 1082)	NC score	0.063794 (rank : 1323)
Query Neighborhood Hits	457	Target Neighborhood Hits	952	Shared Neighborhood Hits	87
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MCF2L_MOUSE
θ value	θ > 10 (rank : 1083)	NC score	0.115269 (rank : 849)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.092064 (rank : 1028)
Query Neighborhood Hits	457	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MDC1_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.051236 (rank : 1508)
Query Neighborhood Hits	457	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDN1_HUMAN
θ value	θ > 10 (rank : 1086)	NC score	0.054033 (rank : 1466)
Query Neighborhood Hits	457	Target Neighborhood Hits	662	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MERL_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.119483 (rank : 820)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	153
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.120731 (rank : 808)
Query Neighborhood Hits	457	Target Neighborhood Hits	524	Shared Neighborhood Hits	155
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MFAP1_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.152067 (rank : 643)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	120
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MFAP1_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.174801 (rank : 555)
Query Neighborhood Hits	457	Target Neighborhood Hits	353	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MICA1_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.052360 (rank : 1497)
Query Neighborhood Hits	457	Target Neighborhood Hits	279	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA1_MOUSE
θ value	θ > 10 (rank : 1092)	NC score	0.094556 (rank : 1012)
Query Neighborhood Hits	457	Target Neighborhood Hits	400	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.053679 (rank : 1475)
Query Neighborhood Hits	457	Target Neighborhood Hits	457	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MINK1_HUMAN
θ value	θ > 10 (rank : 1094)	NC score	0.055029 (rank : 1448)
Query Neighborhood Hits	457	Target Neighborhood Hits	1477	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	θ > 10 (rank : 1095)	NC score	0.054999 (rank : 1450)
Query Neighborhood Hits	457	Target Neighborhood Hits	1451	Shared Neighborhood Hits	177
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINT_HUMAN
θ value	θ > 10 (rank : 1096)	NC score	0.107487 (rank : 898)
Query Neighborhood Hits	457	Target Neighborhood Hits	1291	Shared Neighborhood Hits	158
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	θ > 10 (rank : 1097)	NC score	0.068531 (rank : 1265)
Query Neighborhood Hits	457	Target Neighborhood Hits	1514	Shared Neighborhood Hits	133
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MIPO1_MOUSE
θ value	θ > 10 (rank : 1098)	NC score	0.083130 (rank : 1111)
Query Neighborhood Hits	457	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D9F8	Gene names	Mipol1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein homolog.

MMRN1_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.222485 (rank : 381)
Query Neighborhood Hits	457	Target Neighborhood Hits	636	Shared Neighborhood Hits	148
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MMRN2_HUMAN
θ value	θ > 10 (rank : 1100)	NC score	0.155487 (rank : 631)
Query Neighborhood Hits	457	Target Neighborhood Hits	400	Shared Neighborhood Hits	121
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MOES_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.166606 (rank : 589)
Query Neighborhood Hits	457	Target Neighborhood Hits	892	Shared Neighborhood Hits	201
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MORC3_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.179912 (rank : 540)
Query Neighborhood Hits	457	Target Neighborhood Hits	489	Shared Neighborhood Hits	157
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

MORC4_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.069305 (rank : 1254)
Query Neighborhood Hits	457	Target Neighborhood Hits	244	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MORC4_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.053131 (rank : 1484)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MPP10_MOUSE
θ value	θ > 10 (rank : 1105)	NC score	0.141955 (rank : 693)
Query Neighborhood Hits	457	Target Neighborhood Hits	251	Shared Neighborhood Hits	104
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MPP9_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.241001 (rank : 297)
Query Neighborhood Hits	457	Target Neighborhood Hits	529	Shared Neighborhood Hits	164
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MRCKB_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.153544 (rank : 638)
Query Neighborhood Hits	457	Target Neighborhood Hits	2239	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKG_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.083660 (rank : 1104)
Query Neighborhood Hits	457	Target Neighborhood Hits	1519	Shared Neighborhood Hits	202
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKG_MOUSE
θ value	θ > 10 (rank : 1109)	NC score	0.090039 (rank : 1046)
Query Neighborhood Hits	457	Target Neighborhood Hits	1466	Shared Neighborhood Hits	213
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MTSS1_HUMAN
θ value	θ > 10 (rank : 1110)	NC score	0.050939 (rank : 1509)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	66
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MUTED_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.061829 (rank : 1352)
Query Neighborhood Hits	457	Target Neighborhood Hits	134	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TDH9, Q5THS1, Q68D56, Q8N5F9, Q9NU16	Gene names	MUTED
Domain Architecture	No domain graphic available
Description	Muted protein homolog.

MY18A_HUMAN
θ value	θ > 10 (rank : 1112)	NC score	0.278495 (rank : 166)
Query Neighborhood Hits	457	Target Neighborhood Hits	1929	Shared Neighborhood Hits	271
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH14_HUMAN
θ value	θ > 10 (rank : 1113)	NC score	0.246680 (rank : 278)
Query Neighborhood Hits	457	Target Neighborhood Hits	995	Shared Neighborhood Hits	201
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 1114)	NC score	0.255745 (rank : 246)
Query Neighborhood Hits	457	Target Neighborhood Hits	1225	Shared Neighborhood Hits	224
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYO15_HUMAN
θ value	θ > 10 (rank : 1115)	NC score	0.132045 (rank : 752)
Query Neighborhood Hits	457	Target Neighborhood Hits	671	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO15_MOUSE
θ value	θ > 10 (rank : 1116)	NC score	0.136843 (rank : 722)
Query Neighborhood Hits	457	Target Neighborhood Hits	467	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO1A_HUMAN
θ value	θ > 10 (rank : 1117)	NC score	0.133555 (rank : 743)
Query Neighborhood Hits	457	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

MYO1B_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.132696 (rank : 748)
Query Neighborhood Hits	457	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1B_MOUSE
θ value	θ > 10 (rank : 1119)	NC score	0.132517 (rank : 749)
Query Neighborhood Hits	457	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

MYO1C_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.133653 (rank : 742)
Query Neighborhood Hits	457	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1C_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.133844 (rank : 740)
Query Neighborhood Hits	457	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

MYO1D_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.134087 (rank : 737)
Query Neighborhood Hits	457	Target Neighborhood Hits	56	Shared Neighborhood Hits	25
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1D_MOUSE
θ value	θ > 10 (rank : 1123)	NC score	0.134054 (rank : 738)
Query Neighborhood Hits	457	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

MYO3A_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.096636 (rank : 995)
Query Neighborhood Hits	457	Target Neighborhood Hits	1033	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

MYO3A_MOUSE
θ value	θ > 10 (rank : 1125)	NC score	0.085051 (rank : 1089)
Query Neighborhood Hits	457	Target Neighborhood Hits	902	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

MYO3B_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.086906 (rank : 1078)
Query Neighborhood Hits	457	Target Neighborhood Hits	923	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

MYO5A_HUMAN
θ value	θ > 10 (rank : 1127)	NC score	0.240152 (rank : 299)
Query Neighborhood Hits	457	Target Neighborhood Hits	1092	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 1128)	NC score	0.239415 (rank : 301)
Query Neighborhood Hits	457	Target Neighborhood Hits	1117	Shared Neighborhood Hits	236
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.220801 (rank : 389)
Query Neighborhood Hits	457	Target Neighborhood Hits	911	Shared Neighborhood Hits	212
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 1130)	NC score	0.252839 (rank : 257)
Query Neighborhood Hits	457	Target Neighborhood Hits	1206	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.195228 (rank : 493)
Query Neighborhood Hits	457	Target Neighborhood Hits	727	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO7A_HUMAN
θ value	θ > 10 (rank : 1132)	NC score	0.141226 (rank : 699)
Query Neighborhood Hits	457	Target Neighborhood Hits	209	Shared Neighborhood Hits	72
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	θ > 10 (rank : 1133)	NC score	0.145510 (rank : 675)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	82
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO9B_HUMAN
θ value	θ > 10 (rank : 1134)	NC score	0.128852 (rank : 766)
Query Neighborhood Hits	457	Target Neighborhood Hits	641	Shared Neighborhood Hits	78
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	θ > 10 (rank : 1135)	NC score	0.126734 (rank : 779)
Query Neighborhood Hits	457	Target Neighborhood Hits	311	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYOC_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.097260 (rank : 989)
Query Neighborhood Hits	457	Target Neighborhood Hits	489	Shared Neighborhood Hits	140
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MYPT1_HUMAN
θ value	θ > 10 (rank : 1137)	NC score	0.071758 (rank : 1235)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	149
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT2_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.067750 (rank : 1273)
Query Neighborhood Hits	457	Target Neighborhood Hits	707	Shared Neighborhood Hits	148
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MYT1L_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.071776 (rank : 1234)
Query Neighborhood Hits	457	Target Neighborhood Hits	471	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

MYT1L_MOUSE
θ value	θ > 10 (rank : 1140)	NC score	0.067059 (rank : 1282)
Query Neighborhood Hits	457	Target Neighborhood Hits	461	Shared Neighborhood Hits	111
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

N4BP3_MOUSE
θ value	θ > 10 (rank : 1141)	NC score	0.062415 (rank : 1342)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C7U1, Q3TDC7, Q7TNR2, Q922W0, Q99J06	Gene names	N4bp3
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

NAF1_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.215660 (rank : 411)
Query Neighborhood Hits	457	Target Neighborhood Hits	937	Shared Neighborhood Hits	211
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 1143)	NC score	0.215735 (rank : 410)
Query Neighborhood Hits	457	Target Neighborhood Hits	852	Shared Neighborhood Hits	202
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NARGL_HUMAN
θ value	θ > 10 (rank : 1144)	NC score	0.056757 (rank : 1425)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	77
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NASP_HUMAN
θ value	θ > 10 (rank : 1145)	NC score	0.126290 (rank : 781)
Query Neighborhood Hits	457	Target Neighborhood Hits	709	Shared Neighborhood Hits	142
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NBN_HUMAN
θ value	θ > 10 (rank : 1146)	NC score	0.096821 (rank : 993)
Query Neighborhood Hits	457	Target Neighborhood Hits	226	Shared Neighborhood Hits	73
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

NCOR2_HUMAN
θ value	θ > 10 (rank : 1147)	NC score	0.058673 (rank : 1389)
Query Neighborhood Hits	457	Target Neighborhood Hits	870	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	θ > 10 (rank : 1148)	NC score	0.056073 (rank : 1432)
Query Neighborhood Hits	457	Target Neighborhood Hits	790	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NDEL1_HUMAN
θ value	θ > 10 (rank : 1149)	NC score	0.162648 (rank : 612)
Query Neighborhood Hits	457	Target Neighborhood Hits	415	Shared Neighborhood Hits	129
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
θ value	θ > 10 (rank : 1150)	NC score	0.161891 (rank : 617)
Query Neighborhood Hits	457	Target Neighborhood Hits	420	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

NEB1_HUMAN
θ value	θ > 10 (rank : 1151)	NC score	0.167138 (rank : 585)
Query Neighborhood Hits	457	Target Neighborhood Hits	829	Shared Neighborhood Hits	185
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 1152)	NC score	0.169359 (rank : 578)
Query Neighborhood Hits	457	Target Neighborhood Hits	883	Shared Neighborhood Hits	188
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 1153)	NC score	0.173317 (rank : 558)
Query Neighborhood Hits	457	Target Neighborhood Hits	889	Shared Neighborhood Hits	187
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEMO_HUMAN
θ value	θ > 10 (rank : 1154)	NC score	0.213409 (rank : 420)
Query Neighborhood Hits	457	Target Neighborhood Hits	820	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 1155)	NC score	0.217793 (rank : 400)
Query Neighborhood Hits	457	Target Neighborhood Hits	658	Shared Neighborhood Hits	175
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NEST_HUMAN
θ value	θ > 10 (rank : 1156)	NC score	0.201994 (rank : 463)
Query Neighborhood Hits	457	Target Neighborhood Hits	1305	Shared Neighborhood Hits	213
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NFL_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.111464 (rank : 873)
Query Neighborhood Hits	457	Target Neighborhood Hits	666	Shared Neighborhood Hits	167
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NFL_MOUSE
θ value	θ > 10 (rank : 1158)	NC score	0.110749 (rank : 875)
Query Neighborhood Hits	457	Target Neighborhood Hits	695	Shared Neighborhood Hits	166
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NGAP_HUMAN
θ value	θ > 10 (rank : 1159)	NC score	0.102695 (rank : 943)
Query Neighborhood Hits	457	Target Neighborhood Hits	517	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

NIN_HUMAN
θ value	θ > 10 (rank : 1160)	NC score	0.259577 (rank : 230)
Query Neighborhood Hits	457	Target Neighborhood Hits	1416	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
θ value	θ > 10 (rank : 1161)	NC score	0.258346 (rank : 237)
Query Neighborhood Hits	457	Target Neighborhood Hits	1376	Shared Neighborhood Hits	236
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NIPBL_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.089279 (rank : 1054)
Query Neighborhood Hits	457	Target Neighborhood Hits	1311	Shared Neighborhood Hits	168
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOC3L_MOUSE
θ value	θ > 10 (rank : 1163)	NC score	0.061516 (rank : 1360)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NOE1_HUMAN
θ value	θ > 10 (rank : 1164)	NC score	0.069421 (rank : 1251)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	115
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

NOE1_MOUSE
θ value	θ > 10 (rank : 1165)	NC score	0.065975 (rank : 1298)
Query Neighborhood Hits	457	Target Neighborhood Hits	258	Shared Neighborhood Hits	111
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NOL10_HUMAN
θ value	θ > 10 (rank : 1166)	NC score	0.079463 (rank : 1150)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOL10_MOUSE
θ value	θ > 10 (rank : 1167)	NC score	0.064705 (rank : 1306)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOP14_HUMAN
θ value	θ > 10 (rank : 1168)	NC score	0.160560 (rank : 621)
Query Neighborhood Hits	457	Target Neighborhood Hits	573	Shared Neighborhood Hits	167
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NOP14_MOUSE
θ value	θ > 10 (rank : 1169)	NC score	0.081503 (rank : 1128)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NOXO1_HUMAN
θ value	θ > 10 (rank : 1170)	NC score	0.137102 (rank : 719)
Query Neighborhood Hits	457	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 1171)	NC score	0.204110 (rank : 456)
Query Neighborhood Hits	457	Target Neighborhood Hits	114	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPBL_MOUSE
θ value	θ > 10 (rank : 1172)	NC score	0.064819 (rank : 1305)
Query Neighborhood Hits	457	Target Neighborhood Hits	1041	Shared Neighborhood Hits	117
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NPHP1_HUMAN
θ value	θ > 10 (rank : 1173)	NC score	0.281868 (rank : 144)
Query Neighborhood Hits	457	Target Neighborhood Hits	288	Shared Neighborhood Hits	164
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP3_HUMAN
θ value	θ > 10 (rank : 1174)	NC score	0.059412 (rank : 1378)
Query Neighborhood Hits	457	Target Neighborhood Hits	304	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

NPHP3_MOUSE
θ value	θ > 10 (rank : 1175)	NC score	0.067266 (rank : 1279)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

NRBF2_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.062342 (rank : 1344)
Query Neighborhood Hits	457	Target Neighborhood Hits	122	Shared Neighborhood Hits	54
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

NSBP1_HUMAN
θ value	θ > 10 (rank : 1177)	NC score	0.069995 (rank : 1248)
Query Neighborhood Hits	457	Target Neighborhood Hits	251	Shared Neighborhood Hits	58
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 1178)	NC score	0.054493 (rank : 1458)
Query Neighborhood Hits	457	Target Neighborhood Hits	681	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NTBP1_HUMAN
θ value	θ > 10 (rank : 1179)	NC score	0.073151 (rank : 1219)
Query Neighborhood Hits	457	Target Neighborhood Hits	171	Shared Neighborhood Hits	67
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NTBP1_MOUSE
θ value	θ > 10 (rank : 1180)	NC score	0.153143 (rank : 641)
Query Neighborhood Hits	457	Target Neighborhood Hits	528	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NUCB1_HUMAN
θ value	θ > 10 (rank : 1181)	NC score	0.094175 (rank : 1018)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	102
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB1_MOUSE
θ value	θ > 10 (rank : 1182)	NC score	0.122077 (rank : 803)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	122
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB2_HUMAN
θ value	θ > 10 (rank : 1183)	NC score	0.104234 (rank : 921)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	100
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

NUCB2_MOUSE
θ value	θ > 10 (rank : 1184)	NC score	0.121384 (rank : 804)
Query Neighborhood Hits	457	Target Neighborhood Hits	459	Shared Neighborhood Hits	137
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

NUF2_HUMAN
θ value	θ > 10 (rank : 1185)	NC score	0.259451 (rank : 231)
Query Neighborhood Hits	457	Target Neighborhood Hits	661	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUF2_MOUSE
θ value	θ > 10 (rank : 1186)	NC score	0.236026 (rank : 314)
Query Neighborhood Hits	457	Target Neighborhood Hits	585	Shared Neighborhood Hits	180
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NUP54_HUMAN
θ value	θ > 10 (rank : 1187)	NC score	0.054517 (rank : 1457)
Query Neighborhood Hits	457	Target Neighborhood Hits	93	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

NUP54_MOUSE
θ value	θ > 10 (rank : 1188)	NC score	0.066236 (rank : 1294)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

NUP62_HUMAN
θ value	θ > 10 (rank : 1189)	NC score	0.084698 (rank : 1094)
Query Neighborhood Hits	457	Target Neighborhood Hits	195	Shared Neighborhood Hits	65
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

NUP62_MOUSE
θ value	θ > 10 (rank : 1190)	NC score	0.074880 (rank : 1200)
Query Neighborhood Hits	457	Target Neighborhood Hits	200	Shared Neighborhood Hits	63
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

NUP88_HUMAN
θ value	θ > 10 (rank : 1191)	NC score	0.148482 (rank : 660)
Query Neighborhood Hits	457	Target Neighborhood Hits	354	Shared Neighborhood Hits	128
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

NUP88_MOUSE
θ value	θ > 10 (rank : 1192)	NC score	0.099738 (rank : 962)
Query Neighborhood Hits	457	Target Neighborhood Hits	239	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

OLR1_MOUSE
θ value	θ > 10 (rank : 1193)	NC score	0.153402 (rank : 640)
Query Neighborhood Hits	457	Target Neighborhood Hits	596	Shared Neighborhood Hits	144
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

OPTN_HUMAN
θ value	θ > 10 (rank : 1194)	NC score	0.245174 (rank : 284)
Query Neighborhood Hits	457	Target Neighborhood Hits	827	Shared Neighborhood Hits	208
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 1195)	NC score	0.264070 (rank : 215)
Query Neighborhood Hits	457	Target Neighborhood Hits	1120	Shared Neighborhood Hits	234
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

OTU6B_HUMAN
θ value	θ > 10 (rank : 1196)	NC score	0.091765 (rank : 1032)
Query Neighborhood Hits	457	Target Neighborhood Hits	182	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N6M0, Q9NTA4, Q9Y387	Gene names	OTUD6B
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

OTU6B_MOUSE
θ value	θ > 10 (rank : 1197)	NC score	0.099572 (rank : 965)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

P55G_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.206174 (rank : 450)
Query Neighborhood Hits	457	Target Neighborhood Hits	451	Shared Neighborhood Hits	181
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 1199)	NC score	0.196996 (rank : 480)
Query Neighborhood Hits	457	Target Neighborhood Hits	401	Shared Neighborhood Hits	168
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PALM_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.061692 (rank : 1356)
Query Neighborhood Hits	457	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	O75781, O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3	Gene names	PALM, KIAA0270
Domain Architecture
Description	Paralemmin.

PALM_MOUSE
θ value	θ > 10 (rank : 1201)	NC score	0.057385 (rank : 1409)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PAWR_HUMAN
θ value	θ > 10 (rank : 1202)	NC score	0.106713 (rank : 902)
Query Neighborhood Hits	457	Target Neighborhood Hits	252	Shared Neighborhood Hits	82
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

PCLO_HUMAN
θ value	θ > 10 (rank : 1203)	NC score	0.071798 (rank : 1233)
Query Neighborhood Hits	457	Target Neighborhood Hits	2046	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCNT_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.251955 (rank : 265)
Query Neighborhood Hits	457	Target Neighborhood Hits	1551	Shared Neighborhood Hits	247
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCNT_MOUSE
θ value	θ > 10 (rank : 1205)	NC score	0.235300 (rank : 318)
Query Neighborhood Hits	457	Target Neighborhood Hits	1207	Shared Neighborhood Hits	214
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PCQAP_HUMAN
θ value	θ > 10 (rank : 1206)	NC score	0.056868 (rank : 1423)
Query Neighborhood Hits	457	Target Neighborhood Hits	549	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PDCD7_HUMAN
θ value	θ > 10 (rank : 1207)	NC score	0.069263 (rank : 1256)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PELP1_HUMAN
θ value	θ > 10 (rank : 1208)	NC score	0.053195 (rank : 1479)
Query Neighborhood Hits	457	Target Neighborhood Hits	596	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PEPL_MOUSE
θ value	θ > 10 (rank : 1209)	NC score	0.250513 (rank : 271)
Query Neighborhood Hits	457	Target Neighborhood Hits	1105	Shared Neighborhood Hits	233
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PERI_HUMAN
θ value	θ > 10 (rank : 1210)	NC score	0.097254 (rank : 990)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	147
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

PERI_MOUSE
θ value	θ > 10 (rank : 1211)	NC score	0.097244 (rank : 991)
Query Neighborhood Hits	457	Target Neighborhood Hits	502	Shared Neighborhood Hits	145
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

PFD1_HUMAN
θ value	θ > 10 (rank : 1212)	NC score	0.060089 (rank : 1371)
Query Neighborhood Hits	457	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	O60925, Q53F95, Q96EX6	Gene names	PFDN1, PFD1
Domain Architecture
Description	Prefoldin subunit 1.

PFD4_HUMAN
θ value	θ > 10 (rank : 1213)	NC score	0.063768 (rank : 1325)
Query Neighborhood Hits	457	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQP4, Q5TD11, Q92779	Gene names	PFDN4, PFD4
Domain Architecture	No domain graphic available
Description	Prefoldin subunit 4 (Protein C-1).

PFD6_HUMAN
θ value	θ > 10 (rank : 1214)	NC score	0.063276 (rank : 1335)
Query Neighborhood Hits	457	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PFD6_MOUSE
θ value	θ > 10 (rank : 1215)	NC score	0.081088 (rank : 1131)
Query Neighborhood Hits	457	Target Neighborhood Hits	152	Shared Neighborhood Hits	68
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PHLB1_HUMAN
θ value	θ > 10 (rank : 1216)	NC score	0.143575 (rank : 688)
Query Neighborhood Hits	457	Target Neighborhood Hits	1038	Shared Neighborhood Hits	188
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	θ > 10 (rank : 1217)	NC score	0.109696 (rank : 882)
Query Neighborhood Hits	457	Target Neighborhood Hits	678	Shared Neighborhood Hits	129
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_HUMAN
θ value	θ > 10 (rank : 1218)	NC score	0.213776 (rank : 418)
Query Neighborhood Hits	457	Target Neighborhood Hits	964	Shared Neighborhood Hits	213
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 1219)	NC score	0.215070 (rank : 413)
Query Neighborhood Hits	457	Target Neighborhood Hits	1016	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB3_HUMAN
θ value	θ > 10 (rank : 1220)	NC score	0.120773 (rank : 807)
Query Neighborhood Hits	457	Target Neighborhood Hits	304	Shared Neighborhood Hits	88
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PININ_HUMAN
θ value	θ > 10 (rank : 1221)	NC score	0.181258 (rank : 536)
Query Neighborhood Hits	457	Target Neighborhood Hits	753	Shared Neighborhood Hits	179
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PKHA5_HUMAN
θ value	θ > 10 (rank : 1222)	NC score	0.104152 (rank : 922)
Query Neighborhood Hits	457	Target Neighborhood Hits	455	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHG1_HUMAN
θ value	θ > 10 (rank : 1223)	NC score	0.089593 (rank : 1051)
Query Neighborhood Hits	457	Target Neighborhood Hits	174	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PLCB1_MOUSE
θ value	θ > 10 (rank : 1224)	NC score	0.132889 (rank : 747)
Query Neighborhood Hits	457	Target Neighborhood Hits	531	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB2_HUMAN
θ value	θ > 10 (rank : 1225)	NC score	0.151889 (rank : 644)
Query Neighborhood Hits	457	Target Neighborhood Hits	608	Shared Neighborhood Hits	182
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PLCB3_HUMAN
θ value	θ > 10 (rank : 1226)	NC score	0.118583 (rank : 827)
Query Neighborhood Hits	457	Target Neighborhood Hits	445	Shared Neighborhood Hits	137
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB3_MOUSE
θ value	θ > 10 (rank : 1227)	NC score	0.089414 (rank : 1053)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	114
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLDN_HUMAN
θ value	θ > 10 (rank : 1228)	NC score	0.058414 (rank : 1396)
Query Neighborhood Hits	457	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

PLVAP_HUMAN
θ value	θ > 10 (rank : 1229)	NC score	0.174087 (rank : 557)
Query Neighborhood Hits	457	Target Neighborhood Hits	397	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

PLVAP_MOUSE
θ value	θ > 10 (rank : 1230)	NC score	0.110514 (rank : 877)
Query Neighborhood Hits	457	Target Neighborhood Hits	210	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VC4, Q99JB1	Gene names	Plvap, Pv1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (MECA-32 antigen).

POF1B_HUMAN
θ value	θ > 10 (rank : 1231)	NC score	0.234255 (rank : 320)
Query Neighborhood Hits	457	Target Neighborhood Hits	494	Shared Neighborhood Hits	165
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

POF1B_MOUSE
θ value	θ > 10 (rank : 1232)	NC score	0.237727 (rank : 308)
Query Neighborhood Hits	457	Target Neighborhood Hits	530	Shared Neighborhood Hits	162
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

POT15_HUMAN
θ value	θ > 10 (rank : 1233)	NC score	0.100149 (rank : 960)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	187
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PPIG_HUMAN
θ value	θ > 10 (rank : 1234)	NC score	0.077488 (rank : 1176)
Query Neighborhood Hits	457	Target Neighborhood Hits	670	Shared Neighborhood Hits	142
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PPIP2_HUMAN
θ value	θ > 10 (rank : 1235)	NC score	0.214272 (rank : 416)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 1236)	NC score	0.209651 (rank : 434)
Query Neighborhood Hits	457	Target Neighborhood Hits	308	Shared Neighborhood Hits	129
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRC1_HUMAN
θ value	θ > 10 (rank : 1237)	NC score	0.145153 (rank : 676)
Query Neighborhood Hits	457	Target Neighborhood Hits	328	Shared Neighborhood Hits	117
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PRC1_MOUSE
θ value	θ > 10 (rank : 1238)	NC score	0.148456 (rank : 662)
Query Neighborhood Hits	457	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PREX1_HUMAN
θ value	θ > 10 (rank : 1239)	NC score	0.080098 (rank : 1142)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRP40_HUMAN
θ value	θ > 10 (rank : 1240)	NC score	0.095652 (rank : 1007)
Query Neighborhood Hits	457	Target Neighborhood Hits	442	Shared Neighborhood Hits	115
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 1241)	NC score	0.087088 (rank : 1075)
Query Neighborhood Hits	457	Target Neighborhood Hits	447	Shared Neighborhood Hits	108
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PTN11_HUMAN
θ value	θ > 10 (rank : 1242)	NC score	0.058807 (rank : 1386)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	54
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 1243)	NC score	0.058632 (rank : 1392)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTRF_HUMAN
θ value	θ > 10 (rank : 1244)	NC score	0.079740 (rank : 1147)
Query Neighborhood Hits	457	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q6NZI2, O00535, Q6GMY1, Q96H74, Q9BT85, Q9HAP4	Gene names	PTRF
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor (PTRF protein).

PTRF_MOUSE
θ value	θ > 10 (rank : 1245)	NC score	0.070175 (rank : 1246)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	68
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

RAB3I_HUMAN
θ value	θ > 10 (rank : 1246)	NC score	0.100597 (rank : 959)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	101
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

RABE2_HUMAN
θ value	θ > 10 (rank : 1247)	NC score	0.193765 (rank : 497)
Query Neighborhood Hits	457	Target Neighborhood Hits	545	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_MOUSE
θ value	θ > 10 (rank : 1248)	NC score	0.213208 (rank : 421)
Query Neighborhood Hits	457	Target Neighborhood Hits	598	Shared Neighborhood Hits	170
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RADI_MOUSE
θ value	θ > 10 (rank : 1249)	NC score	0.143011 (rank : 692)
Query Neighborhood Hits	457	Target Neighborhood Hits	773	Shared Neighborhood Hits	180
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RASF8_HUMAN
θ value	θ > 10 (rank : 1250)	NC score	0.184090 (rank : 523)
Query Neighborhood Hits	457	Target Neighborhood Hits	469	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

RASF8_MOUSE
θ value	θ > 10 (rank : 1251)	NC score	0.178509 (rank : 546)
Query Neighborhood Hits	457	Target Neighborhood Hits	391	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

RBBP8_HUMAN
θ value	θ > 10 (rank : 1252)	NC score	0.171357 (rank : 568)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	141
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

RBCC1_HUMAN
θ value	θ > 10 (rank : 1253)	NC score	0.243170 (rank : 292)
Query Neighborhood Hits	457	Target Neighborhood Hits	1023	Shared Neighborhood Hits	213
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 1254)	NC score	0.251403 (rank : 268)
Query Neighborhood Hits	457	Target Neighborhood Hits	1048	Shared Neighborhood Hits	222
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBNS5_MOUSE
θ value	θ > 10 (rank : 1255)	NC score	0.055215 (rank : 1446)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	58
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RBP1_HUMAN
θ value	θ > 10 (rank : 1256)	NC score	0.116943 (rank : 835)
Query Neighborhood Hits	457	Target Neighborhood Hits	521	Shared Neighborhood Hits	145
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	θ > 10 (rank : 1257)	NC score	0.113532 (rank : 860)
Query Neighborhood Hits	457	Target Neighborhood Hits	493	Shared Neighborhood Hits	148
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RFC1_MOUSE
θ value	θ > 10 (rank : 1258)	NC score	0.054253 (rank : 1462)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	67
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RFIP3_HUMAN
θ value	θ > 10 (rank : 1259)	NC score	0.223814 (rank : 376)
Query Neighborhood Hits	457	Target Neighborhood Hits	1055	Shared Neighborhood Hits	200
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 1260)	NC score	0.227055 (rank : 365)
Query Neighborhood Hits	457	Target Neighborhood Hits	785	Shared Neighborhood Hits	201
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
θ value	θ > 10 (rank : 1261)	NC score	0.217553 (rank : 402)
Query Neighborhood Hits	457	Target Neighborhood Hits	708	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RGNEF_MOUSE
θ value	θ > 10 (rank : 1262)	NC score	0.131156 (rank : 759)
Query Neighborhood Hits	457	Target Neighborhood Hits	641	Shared Neighborhood Hits	169
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG25_HUMAN
θ value	θ > 10 (rank : 1263)	NC score	0.089894 (rank : 1048)
Query Neighborhood Hits	457	Target Neighborhood Hits	550	Shared Neighborhood Hits	139
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 1264)	NC score	0.063840 (rank : 1322)
Query Neighborhood Hits	457	Target Neighborhood Hits	492	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIF1_HUMAN
θ value	θ > 10 (rank : 1265)	NC score	0.061918 (rank : 1351)
Query Neighborhood Hits	457	Target Neighborhood Hits	320	Shared Neighborhood Hits	76
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

RILP_HUMAN
θ value	θ > 10 (rank : 1266)	NC score	0.069401 (rank : 1253)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

RILP_MOUSE
θ value	θ > 10 (rank : 1267)	NC score	0.103234 (rank : 934)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	89
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

RIMB1_HUMAN
θ value	θ > 10 (rank : 1268)	NC score	0.276906 (rank : 176)
Query Neighborhood Hits	457	Target Neighborhood Hits	1479	Shared Neighborhood Hits	315
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_MOUSE
θ value	θ > 10 (rank : 1269)	NC score	0.196073 (rank : 485)
Query Neighborhood Hits	457	Target Neighborhood Hits	246	Shared Neighborhood Hits	117
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RN168_MOUSE
θ value	θ > 10 (rank : 1270)	NC score	0.062370 (rank : 1343)
Query Neighborhood Hits	457	Target Neighborhood Hits	440	Shared Neighborhood Hits	81
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF8_HUMAN
θ value	θ > 10 (rank : 1271)	NC score	0.116555 (rank : 841)
Query Neighborhood Hits	457	Target Neighborhood Hits	622	Shared Neighborhood Hits	121
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 1272)	NC score	0.101613 (rank : 955)
Query Neighborhood Hits	457	Target Neighborhood Hits	618	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ROCK2_HUMAN
θ value	θ > 10 (rank : 1273)	NC score	0.148587 (rank : 658)
Query Neighborhood Hits	457	Target Neighborhood Hits	2073	Shared Neighborhood Hits	273
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	θ > 10 (rank : 1274)	NC score	0.151408 (rank : 648)
Query Neighborhood Hits	457	Target Neighborhood Hits	2072	Shared Neighborhood Hits	269
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RP1L1_HUMAN
θ value	θ > 10 (rank : 1275)	NC score	0.062526 (rank : 1339)
Query Neighborhood Hits	457	Target Neighborhood Hits	1072	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPGR1_HUMAN
θ value	θ > 10 (rank : 1276)	NC score	0.199660 (rank : 470)
Query Neighborhood Hits	457	Target Neighborhood Hits	578	Shared Neighborhood Hits	159
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RPGR1_MOUSE
θ value	θ > 10 (rank : 1277)	NC score	0.154045 (rank : 634)
Query Neighborhood Hits	457	Target Neighborhood Hits	713	Shared Neighborhood Hits	160
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RRBP1_HUMAN
θ value	θ > 10 (rank : 1278)	NC score	0.245579 (rank : 283)
Query Neighborhood Hits	457	Target Neighborhood Hits	1306	Shared Neighborhood Hits	223
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRP5_HUMAN
θ value	θ > 10 (rank : 1279)	NC score	0.054065 (rank : 1465)
Query Neighborhood Hits	457	Target Neighborhood Hits	291	Shared Neighborhood Hits	75
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

RT26_HUMAN
θ value	θ > 10 (rank : 1280)	NC score	0.075785 (rank : 1192)
Query Neighborhood Hits	457	Target Neighborhood Hits	75	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYN8, Q96Q58	Gene names	MRPS26, RPMS13
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S26, mitochondrial precursor (MRP-S26) (MRP- S13).

RUFY1_HUMAN
θ value	θ > 10 (rank : 1281)	NC score	0.211793 (rank : 426)
Query Neighborhood Hits	457	Target Neighborhood Hits	848	Shared Neighborhood Hits	196
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 1282)	NC score	0.201405 (rank : 465)
Query Neighborhood Hits	457	Target Neighborhood Hits	765	Shared Neighborhood Hits	179
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_MOUSE
θ value	θ > 10 (rank : 1283)	NC score	0.211192 (rank : 429)
Query Neighborhood Hits	457	Target Neighborhood Hits	820	Shared Neighborhood Hits	186
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY3_HUMAN
θ value	θ > 10 (rank : 1284)	NC score	0.209036 (rank : 439)
Query Neighborhood Hits	457	Target Neighborhood Hits	594	Shared Neighborhood Hits	183
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 1285)	NC score	0.204814 (rank : 454)
Query Neighborhood Hits	457	Target Neighborhood Hits	579	Shared Neighborhood Hits	180
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUSC2_HUMAN
θ value	θ > 10 (rank : 1286)	NC score	0.069264 (rank : 1255)
Query Neighborhood Hits	457	Target Neighborhood Hits	205	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC2_MOUSE
θ value	θ > 10 (rank : 1287)	NC score	0.069009 (rank : 1257)
Query Neighborhood Hits	457	Target Neighborhood Hits	305	Shared Neighborhood Hits	61
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

S6OS1_HUMAN
θ value	θ > 10 (rank : 1288)	NC score	0.066812 (rank : 1285)
Query Neighborhood Hits	457	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1H7	Gene names	SIX6OS1, C14orf39
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

S6OS1_MOUSE
θ value	θ > 10 (rank : 1289)	NC score	0.054885 (rank : 1453)
Query Neighborhood Hits	457	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

SAFB2_HUMAN
θ value	θ > 10 (rank : 1290)	NC score	0.113965 (rank : 859)
Query Neighborhood Hits	457	Target Neighborhood Hits	720	Shared Neighborhood Hits	143
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SAFB2_MOUSE
θ value	θ > 10 (rank : 1291)	NC score	0.089059 (rank : 1056)
Query Neighborhood Hits	457	Target Neighborhood Hits	581	Shared Neighborhood Hits	125
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SAKS1_HUMAN
θ value	θ > 10 (rank : 1292)	NC score	0.060051 (rank : 1373)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	51
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SAKS1_MOUSE
θ value	θ > 10 (rank : 1293)	NC score	0.062516 (rank : 1341)
Query Neighborhood Hits	457	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SAS6_MOUSE
θ value	θ > 10 (rank : 1294)	NC score	0.260758 (rank : 223)
Query Neighborhood Hits	457	Target Neighborhood Hits	931	Shared Neighborhood Hits	217
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SASH1_HUMAN
θ value	θ > 10 (rank : 1295)	NC score	0.054948 (rank : 1451)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	57
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SASH1_MOUSE
θ value	θ > 10 (rank : 1296)	NC score	0.050485 (rank : 1516)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	59
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SCG2_HUMAN
θ value	θ > 10 (rank : 1297)	NC score	0.053284 (rank : 1477)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

SCG3_MOUSE
θ value	θ > 10 (rank : 1298)	NC score	0.086469 (rank : 1080)
Query Neighborhood Hits	457	Target Neighborhood Hits	170	Shared Neighborhood Hits	70
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

SDCG1_HUMAN
θ value	θ > 10 (rank : 1299)	NC score	0.063634 (rank : 1328)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

SDCG8_HUMAN
θ value	θ > 10 (rank : 1300)	NC score	0.262681 (rank : 221)
Query Neighborhood Hits	457	Target Neighborhood Hits	1002	Shared Neighborhood Hits	219
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 1301)	NC score	0.242104 (rank : 294)
Query Neighborhood Hits	457	Target Neighborhood Hits	886	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SDPR_HUMAN
θ value	θ > 10 (rank : 1302)	NC score	0.139299 (rank : 705)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	108
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SDS3_HUMAN
θ value	θ > 10 (rank : 1303)	NC score	0.109356 (rank : 885)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SDS3_MOUSE
θ value	θ > 10 (rank : 1304)	NC score	0.105086 (rank : 914)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SEC20_HUMAN
θ value	θ > 10 (rank : 1305)	NC score	0.118408 (rank : 829)
Query Neighborhood Hits	457	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SEC20_MOUSE
θ value	θ > 10 (rank : 1306)	NC score	0.154145 (rank : 633)
Query Neighborhood Hits	457	Target Neighborhood Hits	323	Shared Neighborhood Hits	117
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

SEMG1_HUMAN
θ value	θ > 10 (rank : 1307)	NC score	0.064121 (rank : 1319)
Query Neighborhood Hits	457	Target Neighborhood Hits	200	Shared Neighborhood Hits	48
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEMG2_HUMAN
θ value	θ > 10 (rank : 1308)	NC score	0.067899 (rank : 1270)
Query Neighborhood Hits	457	Target Neighborhood Hits	251	Shared Neighborhood Hits	51
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SEPT7_HUMAN
θ value	θ > 10 (rank : 1309)	NC score	0.060023 (rank : 1374)
Query Neighborhood Hits	457	Target Neighborhood Hits	385	Shared Neighborhood Hits	117
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT7_MOUSE
θ value	θ > 10 (rank : 1310)	NC score	0.058344 (rank : 1399)
Query Neighborhood Hits	457	Target Neighborhood Hits	327	Shared Neighborhood Hits	100
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SFR17_HUMAN
θ value	θ > 10 (rank : 1311)	NC score	0.069415 (rank : 1252)
Query Neighborhood Hits	457	Target Neighborhood Hits	325	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SGOL2_HUMAN
θ value	θ > 10 (rank : 1312)	NC score	0.105483 (rank : 910)
Query Neighborhood Hits	457	Target Neighborhood Hits	207	Shared Neighborhood Hits	71
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SH21A_HUMAN
θ value	θ > 10 (rank : 1313)	NC score	0.066940 (rank : 1283)
Query Neighborhood Hits	457	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 1314)	NC score	0.064192 (rank : 1315)
Query Neighborhood Hits	457	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 1315)	NC score	0.085741 (rank : 1085)
Query Neighborhood Hits	457	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 1316)	NC score	0.093344 (rank : 1022)
Query Neighborhood Hits	457	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
θ value	θ > 10 (rank : 1317)	NC score	0.058901 (rank : 1384)
Query Neighborhood Hits	457	Target Neighborhood Hits	144	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 1318)	NC score	0.061658 (rank : 1357)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH24A_HUMAN
θ value	θ > 10 (rank : 1319)	NC score	0.170485 (rank : 573)
Query Neighborhood Hits	457	Target Neighborhood Hits	455	Shared Neighborhood Hits	154
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SH24A_MOUSE
θ value	θ > 10 (rank : 1320)	NC score	0.118431 (rank : 828)
Query Neighborhood Hits	457	Target Neighborhood Hits	326	Shared Neighborhood Hits	117
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SH2D3_HUMAN
θ value	θ > 10 (rank : 1321)	NC score	0.055419 (rank : 1444)
Query Neighborhood Hits	457	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 1322)	NC score	0.057554 (rank : 1408)
Query Neighborhood Hits	457	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHAN2_MOUSE
θ value	θ > 10 (rank : 1323)	NC score	0.126088 (rank : 782)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	99
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHB_HUMAN
θ value	θ > 10 (rank : 1324)	NC score	0.083354 (rank : 1108)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_MOUSE
θ value	θ > 10 (rank : 1325)	NC score	0.085028 (rank : 1090)
Query Neighborhood Hits	457	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC1_HUMAN
θ value	θ > 10 (rank : 1326)	NC score	0.077874 (rank : 1171)
Query Neighborhood Hits	457	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 1327)	NC score	0.082645 (rank : 1115)
Query Neighborhood Hits	457	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 1328)	NC score	0.076430 (rank : 1184)
Query Neighborhood Hits	457	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 1329)	NC score	0.076226 (rank : 1186)
Query Neighborhood Hits	457	Target Neighborhood Hits	144	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 1330)	NC score	0.078849 (rank : 1155)
Query Neighborhood Hits	457	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 1331)	NC score	0.083294 (rank : 1109)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	51
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_HUMAN
θ value	θ > 10 (rank : 1332)	NC score	0.078355 (rank : 1162)
Query Neighborhood Hits	457	Target Neighborhood Hits	204	Shared Neighborhood Hits	49
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_MOUSE
θ value	θ > 10 (rank : 1333)	NC score	0.078610 (rank : 1159)
Query Neighborhood Hits	457	Target Neighborhood Hits	137	Shared Neighborhood Hits	50
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
θ value	θ > 10 (rank : 1334)	NC score	0.082302 (rank : 1119)
Query Neighborhood Hits	457	Target Neighborhood Hits	164	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHE_MOUSE
θ value	θ > 10 (rank : 1335)	NC score	0.084776 (rank : 1093)
Query Neighborhood Hits	457	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SIL1_MOUSE
θ value	θ > 10 (rank : 1336)	NC score	0.052667 (rank : 1490)
Query Neighborhood Hits	457	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q9EPK6, Q91V34	Gene names	Sil1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor.

SKIL_HUMAN
θ value	θ > 10 (rank : 1337)	NC score	0.139619 (rank : 703)
Query Neighborhood Hits	457	Target Neighborhood Hits	460	Shared Neighborhood Hits	141
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SKIL_MOUSE
θ value	θ > 10 (rank : 1338)	NC score	0.172865 (rank : 561)
Query Neighborhood Hits	457	Target Neighborhood Hits	719	Shared Neighborhood Hits	193
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SKI_HUMAN
θ value	θ > 10 (rank : 1339)	NC score	0.127287 (rank : 776)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	132
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SKI_MOUSE
θ value	θ > 10 (rank : 1340)	NC score	0.134463 (rank : 735)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	132
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

SLAP1_HUMAN
θ value	θ > 10 (rank : 1341)	NC score	0.137704 (rank : 715)
Query Neighborhood Hits	457	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 1342)	NC score	0.137277 (rank : 718)
Query Neighborhood Hits	457	Target Neighborhood Hits	117	Shared Neighborhood Hits	45
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 1343)	NC score	0.145628 (rank : 673)
Query Neighborhood Hits	457	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 1344)	NC score	0.146284 (rank : 669)
Query Neighborhood Hits	457	Target Neighborhood Hits	136	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLK_MOUSE
θ value	θ > 10 (rank : 1345)	NC score	0.087765 (rank : 1066)
Query Neighborhood Hits	457	Target Neighborhood Hits	1798	Shared Neighborhood Hits	237
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SLY_HUMAN
θ value	θ > 10 (rank : 1346)	NC score	0.073883 (rank : 1211)
Query Neighborhood Hits	457	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	θ > 10 (rank : 1347)	NC score	0.087350 (rank : 1069)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SM1L2_MOUSE
θ value	θ > 10 (rank : 1348)	NC score	0.287575 (rank : 125)
Query Neighborhood Hits	457	Target Neighborhood Hits	918	Shared Neighborhood Hits	220
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMCE1_HUMAN
θ value	θ > 10 (rank : 1349)	NC score	0.064915 (rank : 1304)
Query Neighborhood Hits	457	Target Neighborhood Hits	272	Shared Neighborhood Hits	69
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	θ > 10 (rank : 1350)	NC score	0.079495 (rank : 1148)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	80
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SNIP_HUMAN
θ value	θ > 10 (rank : 1351)	NC score	0.058414 (rank : 1395)
Query Neighborhood Hits	457	Target Neighborhood Hits	313	Shared Neighborhood Hits	71
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SNP25_HUMAN
θ value	θ > 10 (rank : 1352)	NC score	0.079851 (rank : 1145)
Query Neighborhood Hits	457	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	P60880, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	SNAP25, SNAP
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNP25_MOUSE
θ value	θ > 10 (rank : 1353)	NC score	0.079851 (rank : 1146)
Query Neighborhood Hits	457	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	P60879, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	Snap25, Snap
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNPH_HUMAN
θ value	θ > 10 (rank : 1354)	NC score	0.115412 (rank : 848)
Query Neighborhood Hits	457	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

SNX9_HUMAN
θ value	θ > 10 (rank : 1355)	NC score	0.153438 (rank : 639)
Query Neighborhood Hits	457	Target Neighborhood Hits	148	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SNX9_MOUSE
θ value	θ > 10 (rank : 1356)	NC score	0.138447 (rank : 711)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SOCS6_HUMAN
θ value	θ > 10 (rank : 1357)	NC score	0.051947 (rank : 1501)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	37
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SOCS6_MOUSE
θ value	θ > 10 (rank : 1358)	NC score	0.053734 (rank : 1472)
Query Neighborhood Hits	457	Target Neighborhood Hits	146	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SOCS7_MOUSE
θ value	θ > 10 (rank : 1359)	NC score	0.060512 (rank : 1365)
Query Neighborhood Hits	457	Target Neighborhood Hits	154	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SPAG5_HUMAN
θ value	θ > 10 (rank : 1360)	NC score	0.210601 (rank : 432)
Query Neighborhood Hits	457	Target Neighborhood Hits	625	Shared Neighborhood Hits	176
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SPAG5_MOUSE
θ value	θ > 10 (rank : 1361)	NC score	0.217793 (rank : 401)
Query Neighborhood Hits	457	Target Neighborhood Hits	612	Shared Neighborhood Hits	159
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPC24_HUMAN
θ value	θ > 10 (rank : 1362)	NC score	0.171065 (rank : 571)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SPC24_MOUSE
θ value	θ > 10 (rank : 1363)	NC score	0.055787 (rank : 1437)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D083, Q3TIF5, Q8CD13	Gene names	Spbc24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24.

SPC25_HUMAN
θ value	θ > 10 (rank : 1364)	NC score	0.161782 (rank : 618)
Query Neighborhood Hits	457	Target Neighborhood Hits	273	Shared Neighborhood Hits	121
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

SPC25_MOUSE
θ value	θ > 10 (rank : 1365)	NC score	0.125347 (rank : 787)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	98
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

SPTB1_HUMAN
θ value	θ > 10 (rank : 1366)	NC score	0.144999 (rank : 677)
Query Neighborhood Hits	457	Target Neighborhood Hits	541	Shared Neighborhood Hits	151
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
θ value	θ > 10 (rank : 1367)	NC score	0.147773 (rank : 666)
Query Neighborhood Hits	457	Target Neighborhood Hits	543	Shared Neighborhood Hits	162
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB2_HUMAN
θ value	θ > 10 (rank : 1368)	NC score	0.185956 (rank : 520)
Query Neighborhood Hits	457	Target Neighborhood Hits	748	Shared Neighborhood Hits	187
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	θ > 10 (rank : 1369)	NC score	0.188993 (rank : 510)
Query Neighborhood Hits	457	Target Neighborhood Hits	770	Shared Neighborhood Hits	191
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN2_HUMAN
θ value	θ > 10 (rank : 1370)	NC score	0.098297 (rank : 981)
Query Neighborhood Hits	457	Target Neighborhood Hits	535	Shared Neighborhood Hits	137
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTN4_HUMAN
θ value	θ > 10 (rank : 1371)	NC score	0.104531 (rank : 919)
Query Neighborhood Hits	457	Target Neighborhood Hits	570	Shared Neighborhood Hits	138
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SPTN5_HUMAN
θ value	θ > 10 (rank : 1372)	NC score	0.114617 (rank : 856)
Query Neighborhood Hits	457	Target Neighborhood Hits	674	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SRGP1_HUMAN
θ value	θ > 10 (rank : 1373)	NC score	0.176093 (rank : 553)
Query Neighborhood Hits	457	Target Neighborhood Hits	390	Shared Neighborhood Hits	182
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 1374)	NC score	0.171309 (rank : 570)
Query Neighborhood Hits	457	Target Neighborhood Hits	331	Shared Neighborhood Hits	166
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 1375)	NC score	0.172896 (rank : 560)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	168
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRMS_HUMAN
θ value	θ > 10 (rank : 1376)	NC score	0.064105 (rank : 1320)
Query Neighborhood Hits	457	Target Neighborhood Hits	946	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SSNA1_HUMAN
θ value	θ > 10 (rank : 1377)	NC score	0.126297 (rank : 780)
Query Neighborhood Hits	457	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	O43805, Q6FG70, Q9BVW8	Gene names	SSNA1, NA14
Domain Architecture
Description	Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa).

SSNA1_MOUSE
θ value	θ > 10 (rank : 1378)	NC score	0.135163 (rank : 731)
Query Neighborhood Hits	457	Target Neighborhood Hits	182	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

ST18_HUMAN
θ value	θ > 10 (rank : 1379)	NC score	0.063658 (rank : 1326)
Query Neighborhood Hits	457	Target Neighborhood Hits	252	Shared Neighborhood Hits	91
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

ST18_MOUSE
θ value	θ > 10 (rank : 1380)	NC score	0.059159 (rank : 1382)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

STAM1_HUMAN
θ value	θ > 10 (rank : 1381)	NC score	0.347272 (rank : 73)
Query Neighborhood Hits	457	Target Neighborhood Hits	271	Shared Neighborhood Hits	153
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 1382)	NC score	0.352740 (rank : 70)
Query Neighborhood Hits	457	Target Neighborhood Hits	273	Shared Neighborhood Hits	153
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STIM1_HUMAN
θ value	θ > 10 (rank : 1383)	NC score	0.181928 (rank : 532)
Query Neighborhood Hits	457	Target Neighborhood Hits	665	Shared Neighborhood Hits	186
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	θ > 10 (rank : 1384)	NC score	0.181084 (rank : 537)
Query Neighborhood Hits	457	Target Neighborhood Hits	660	Shared Neighborhood Hits	193
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM2_HUMAN
θ value	θ > 10 (rank : 1385)	NC score	0.127862 (rank : 773)
Query Neighborhood Hits	457	Target Neighborhood Hits	420	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

STIM2_MOUSE
θ value	θ > 10 (rank : 1386)	NC score	0.124460 (rank : 793)
Query Neighborhood Hits	457	Target Neighborhood Hits	403	Shared Neighborhood Hits	149
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

STK10_HUMAN
θ value	θ > 10 (rank : 1387)	NC score	0.110055 (rank : 880)
Query Neighborhood Hits	457	Target Neighborhood Hits	1921	Shared Neighborhood Hits	254
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK31_HUMAN
θ value	θ > 10 (rank : 1388)	NC score	0.090105 (rank : 1045)
Query Neighborhood Hits	457	Target Neighborhood Hits	570	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

STMN1_MOUSE
θ value	θ > 10 (rank : 1389)	NC score	0.160593 (rank : 620)
Query Neighborhood Hits	457	Target Neighborhood Hits	560	Shared Neighborhood Hits	167
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

STMN2_HUMAN
θ value	θ > 10 (rank : 1390)	NC score	0.120119 (rank : 812)
Query Neighborhood Hits	457	Target Neighborhood Hits	458	Shared Neighborhood Hits	138
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	θ > 10 (rank : 1391)	NC score	0.120119 (rank : 813)
Query Neighborhood Hits	457	Target Neighborhood Hits	458	Shared Neighborhood Hits	138
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN3_HUMAN
θ value	θ > 10 (rank : 1392)	NC score	0.109020 (rank : 886)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NZ72, O75527, Q969Y4	Gene names	STMN3, SCLIP
Domain Architecture
Description	Stathmin-3 (SCG10-like protein).

STMN3_MOUSE
θ value	θ > 10 (rank : 1393)	NC score	0.093803 (rank : 1019)
Query Neighborhood Hits	457	Target Neighborhood Hits	331	Shared Neighborhood Hits	113
SwissProt Accessions	O70166	Gene names	Stmn3, Sclip
Domain Architecture
Description	Stathmin-3 (SCG10-like protein) (SCG10-related protein HiAT3) (Hippocampus abundant transcript 3).

STMN4_HUMAN
θ value	θ > 10 (rank : 1394)	NC score	0.112004 (rank : 864)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	134
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	θ > 10 (rank : 1395)	NC score	0.111977 (rank : 865)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	134
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STX12_HUMAN
θ value	θ > 10 (rank : 1396)	NC score	0.080072 (rank : 1143)
Query Neighborhood Hits	457	Target Neighborhood Hits	226	Shared Neighborhood Hits	94
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

STX12_MOUSE
θ value	θ > 10 (rank : 1397)	NC score	0.107564 (rank : 897)
Query Neighborhood Hits	457	Target Neighborhood Hits	283	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

STX18_HUMAN
θ value	θ > 10 (rank : 1398)	NC score	0.080120 (rank : 1140)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

STX1A_HUMAN
θ value	θ > 10 (rank : 1399)	NC score	0.077718 (rank : 1173)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	105
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1A_MOUSE
θ value	θ > 10 (rank : 1400)	NC score	0.074838 (rank : 1201)
Query Neighborhood Hits	457	Target Neighborhood Hits	261	Shared Neighborhood Hits	102
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1B_HUMAN
θ value	θ > 10 (rank : 1401)	NC score	0.078556 (rank : 1161)
Query Neighborhood Hits	457	Target Neighborhood Hits	252	Shared Neighborhood Hits	99
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

STX1C_HUMAN
θ value	θ > 10 (rank : 1402)	NC score	0.103326 (rank : 931)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	115
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
θ value	θ > 10 (rank : 1403)	NC score	0.103326 (rank : 932)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	115
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

STX2_HUMAN
θ value	θ > 10 (rank : 1404)	NC score	0.051428 (rank : 1506)
Query Neighborhood Hits	457	Target Neighborhood Hits	158	Shared Neighborhood Hits	72
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

STX3_HUMAN
θ value	θ > 10 (rank : 1405)	NC score	0.066409 (rank : 1292)
Query Neighborhood Hits	457	Target Neighborhood Hits	211	Shared Neighborhood Hits	89
SwissProt Accessions	Q13277, O43750, O43751, Q15360	Gene names	STX3, STX3A
Domain Architecture
Description	Syntaxin-3.

STX3_MOUSE
θ value	θ > 10 (rank : 1406)	NC score	0.067436 (rank : 1278)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	89
SwissProt Accessions	Q64704	Gene names	Stx3, Stx3a
Domain Architecture
Description	Syntaxin-3.

STX4_HUMAN
θ value	θ > 10 (rank : 1407)	NC score	0.097726 (rank : 987)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	103
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

STX4_MOUSE
θ value	θ > 10 (rank : 1408)	NC score	0.116296 (rank : 842)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	116
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

STXB4_HUMAN
θ value	θ > 10 (rank : 1409)	NC score	0.170280 (rank : 574)
Query Neighborhood Hits	457	Target Neighborhood Hits	616	Shared Neighborhood Hits	166
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 1410)	NC score	0.150362 (rank : 653)
Query Neighborhood Hits	457	Target Neighborhood Hits	629	Shared Neighborhood Hits	162
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SURF6_MOUSE
θ value	θ > 10 (rank : 1411)	NC score	0.075949 (rank : 1190)
Query Neighborhood Hits	457	Target Neighborhood Hits	195	Shared Neighborhood Hits	62
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

SWP70_HUMAN
θ value	θ > 10 (rank : 1412)	NC score	0.208663 (rank : 442)
Query Neighborhood Hits	457	Target Neighborhood Hits	973	Shared Neighborhood Hits	205
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 1413)	NC score	0.211246 (rank : 428)
Query Neighborhood Hits	457	Target Neighborhood Hits	1097	Shared Neighborhood Hits	214
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYBU_HUMAN
θ value	θ > 10 (rank : 1414)	NC score	0.062033 (rank : 1348)
Query Neighborhood Hits	457	Target Neighborhood Hits	188	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

SYBU_MOUSE
θ value	θ > 10 (rank : 1415)	NC score	0.065126 (rank : 1302)
Query Neighborhood Hits	457	Target Neighborhood Hits	214	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

SYCP2_HUMAN
θ value	θ > 10 (rank : 1416)	NC score	0.101251 (rank : 957)
Query Neighborhood Hits	457	Target Neighborhood Hits	230	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

SYCP3_HUMAN
θ value	θ > 10 (rank : 1417)	NC score	0.097456 (rank : 988)
Query Neighborhood Hits	457	Target Neighborhood Hits	276	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

SYCP3_MOUSE
θ value	θ > 10 (rank : 1418)	NC score	0.077773 (rank : 1172)
Query Neighborhood Hits	457	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

SYGP1_HUMAN
θ value	θ > 10 (rank : 1419)	NC score	0.103815 (rank : 928)
Query Neighborhood Hits	457	Target Neighborhood Hits	589	Shared Neighborhood Hits	152
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

T2_MOUSE
θ value	θ > 10 (rank : 1420)	NC score	0.065638 (rank : 1299)
Query Neighborhood Hits	457	Target Neighborhood Hits	140	Shared Neighborhood Hits	36
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

T3JAM_HUMAN
θ value	θ > 10 (rank : 1421)	NC score	0.211991 (rank : 425)
Query Neighborhood Hits	457	Target Neighborhood Hits	533	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

T3JAM_MOUSE
θ value	θ > 10 (rank : 1422)	NC score	0.185800 (rank : 521)
Query Neighborhood Hits	457	Target Neighborhood Hits	535	Shared Neighborhood Hits	146
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TACC1_HUMAN
θ value	θ > 10 (rank : 1423)	NC score	0.199577 (rank : 472)
Query Neighborhood Hits	457	Target Neighborhood Hits	597	Shared Neighborhood Hits	175
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	θ > 10 (rank : 1424)	NC score	0.199266 (rank : 473)
Query Neighborhood Hits	457	Target Neighborhood Hits	667	Shared Neighborhood Hits	177
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC2_HUMAN
θ value	θ > 10 (rank : 1425)	NC score	0.201046 (rank : 468)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	202
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 1426)	NC score	0.185724 (rank : 522)
Query Neighborhood Hits	457	Target Neighborhood Hits	774	Shared Neighborhood Hits	181
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TACC3_HUMAN
θ value	θ > 10 (rank : 1427)	NC score	0.190208 (rank : 506)
Query Neighborhood Hits	457	Target Neighborhood Hits	779	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TACC3_MOUSE
θ value	θ > 10 (rank : 1428)	NC score	0.203047 (rank : 459)
Query Neighborhood Hits	457	Target Neighborhood Hits	607	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TAD3L_HUMAN
θ value	θ > 10 (rank : 1429)	NC score	0.064322 (rank : 1312)
Query Neighborhood Hits	457	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	θ > 10 (rank : 1430)	NC score	0.063648 (rank : 1327)
Query Neighborhood Hits	457	Target Neighborhood Hits	188	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAF4_HUMAN
θ value	θ > 10 (rank : 1431)	NC score	0.053884 (rank : 1468)
Query Neighborhood Hits	457	Target Neighborhood Hits	687	Shared Neighborhood Hits	92
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAF7_HUMAN
θ value	θ > 10 (rank : 1432)	NC score	0.121129 (rank : 805)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	98
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TAF7_MOUSE
θ value	θ > 10 (rank : 1433)	NC score	0.119952 (rank : 814)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TAK1L_HUMAN
θ value	θ > 10 (rank : 1434)	NC score	0.059295 (rank : 1379)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

TAK1L_MOUSE
θ value	θ > 10 (rank : 1435)	NC score	0.071636 (rank : 1236)
Query Neighborhood Hits	457	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	P58500	Gene names	Tak1l, ORF63
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

TAOK1_HUMAN
θ value	θ > 10 (rank : 1436)	NC score	0.108003 (rank : 895)
Query Neighborhood Hits	457	Target Neighborhood Hits	1734	Shared Neighborhood Hits	252
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
θ value	θ > 10 (rank : 1437)	NC score	0.107431 (rank : 899)
Query Neighborhood Hits	457	Target Neighborhood Hits	1720	Shared Neighborhood Hits	251
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK2_MOUSE
θ value	θ > 10 (rank : 1438)	NC score	0.071555 (rank : 1237)
Query Neighborhood Hits	457	Target Neighborhood Hits	1373	Shared Neighborhood Hits	191
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

TARA_HUMAN
θ value	θ > 10 (rank : 1439)	NC score	0.128443 (rank : 768)
Query Neighborhood Hits	457	Target Neighborhood Hits	1626	Shared Neighborhood Hits	195
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	θ > 10 (rank : 1440)	NC score	0.143587 (rank : 687)
Query Neighborhood Hits	457	Target Neighborhood Hits	1133	Shared Neighborhood Hits	180
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAXB1_HUMAN
θ value	θ > 10 (rank : 1441)	NC score	0.283666 (rank : 137)
Query Neighborhood Hits	457	Target Neighborhood Hits	829	Shared Neighborhood Hits	212
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 1442)	NC score	0.275783 (rank : 182)
Query Neighborhood Hits	457	Target Neighborhood Hits	886	Shared Neighborhood Hits	213
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TBCD2_HUMAN
θ value	θ > 10 (rank : 1443)	NC score	0.106705 (rank : 903)
Query Neighborhood Hits	457	Target Neighborhood Hits	419	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TBCD4_HUMAN
θ value	θ > 10 (rank : 1444)	NC score	0.066023 (rank : 1297)
Query Neighborhood Hits	457	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TCAL5_HUMAN
θ value	θ > 10 (rank : 1445)	NC score	0.053765 (rank : 1470)
Query Neighborhood Hits	457	Target Neighborhood Hits	806	Shared Neighborhood Hits	86
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCGAP_HUMAN
θ value	θ > 10 (rank : 1446)	NC score	0.101582 (rank : 956)
Query Neighborhood Hits	457	Target Neighborhood Hits	872	Shared Neighborhood Hits	121
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 1447)	NC score	0.114751 (rank : 853)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	114
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCRG1_HUMAN
θ value	θ > 10 (rank : 1448)	NC score	0.189883 (rank : 507)
Query Neighborhood Hits	457	Target Neighborhood Hits	929	Shared Neighborhood Hits	185
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1449)	NC score	0.189411 (rank : 509)
Query Neighborhood Hits	457	Target Neighborhood Hits	947	Shared Neighborhood Hits	186
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEC_HUMAN
θ value	θ > 10 (rank : 1450)	NC score	0.084218 (rank : 1098)
Query Neighborhood Hits	457	Target Neighborhood Hits	1006	Shared Neighborhood Hits	133
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1451)	NC score	0.082116 (rank : 1122)
Query Neighborhood Hits	457	Target Neighborhood Hits	1006	Shared Neighborhood Hits	131
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEKT1_HUMAN
θ value	θ > 10 (rank : 1452)	NC score	0.179311 (rank : 541)
Query Neighborhood Hits	457	Target Neighborhood Hits	289	Shared Neighborhood Hits	128
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

TEKT1_MOUSE
θ value	θ > 10 (rank : 1453)	NC score	0.195660 (rank : 490)
Query Neighborhood Hits	457	Target Neighborhood Hits	399	Shared Neighborhood Hits	146
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TEKT2_HUMAN
θ value	θ > 10 (rank : 1454)	NC score	0.082194 (rank : 1120)
Query Neighborhood Hits	457	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

TEKT2_MOUSE
θ value	θ > 10 (rank : 1455)	NC score	0.102849 (rank : 940)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q922G7, Q9WVR0	Gene names	Tekt2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t).

TEKT3_HUMAN
θ value	θ > 10 (rank : 1456)	NC score	0.083678 (rank : 1103)
Query Neighborhood Hits	457	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXF9, Q8N5R5, Q96M48	Gene names	TEKT3
Domain Architecture
Description	Tektin-3.

TEKT3_MOUSE
θ value	θ > 10 (rank : 1457)	NC score	0.069794 (rank : 1249)
Query Neighborhood Hits	457	Target Neighborhood Hits	123	Shared Neighborhood Hits	55
SwissProt Accessions	Q6X6Z7	Gene names	Tekt3
Domain Architecture	No domain graphic available
Description	Tektin-3.

TEX14_HUMAN
θ value	θ > 10 (rank : 1458)	NC score	0.068770 (rank : 1261)
Query Neighborhood Hits	457	Target Neighborhood Hits	1103	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
θ value	θ > 10 (rank : 1459)	NC score	0.094536 (rank : 1013)
Query Neighborhood Hits	457	Target Neighborhood Hits	1333	Shared Neighborhood Hits	179
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX9_MOUSE
θ value	θ > 10 (rank : 1460)	NC score	0.243758 (rank : 288)
Query Neighborhood Hits	457	Target Neighborhood Hits	581	Shared Neighborhood Hits	182
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TFAP4_HUMAN
θ value	θ > 10 (rank : 1461)	NC score	0.082146 (rank : 1121)
Query Neighborhood Hits	457	Target Neighborhood Hits	289	Shared Neighborhood Hits	78
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

THOC2_HUMAN
θ value	θ > 10 (rank : 1462)	NC score	0.056933 (rank : 1422)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TIAM1_HUMAN
θ value	θ > 10 (rank : 1463)	NC score	0.080520 (rank : 1135)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 1464)	NC score	0.081593 (rank : 1127)
Query Neighborhood Hits	457	Target Neighborhood Hits	205	Shared Neighborhood Hits	30
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIM44_HUMAN
θ value	θ > 10 (rank : 1465)	NC score	0.072212 (rank : 1231)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	69
SwissProt Accessions	O43615, Q8N193	Gene names	TIMM44, MIMT44, TIM44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TIM44_MOUSE
θ value	θ > 10 (rank : 1466)	NC score	0.096847 (rank : 992)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	100
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TJAP1_HUMAN
θ value	θ > 10 (rank : 1467)	NC score	0.080100 (rank : 1141)
Query Neighborhood Hits	457	Target Neighborhood Hits	214	Shared Neighborhood Hits	74
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TJAP1_MOUSE
θ value	θ > 10 (rank : 1468)	NC score	0.099539 (rank : 966)
Query Neighborhood Hits	457	Target Neighborhood Hits	295	Shared Neighborhood Hits	102
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TLK2_MOUSE
θ value	θ > 10 (rank : 1469)	NC score	0.056098 (rank : 1430)
Query Neighborhood Hits	457	Target Neighborhood Hits	1088	Shared Neighborhood Hits	156
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

TMCC1_HUMAN
θ value	θ > 10 (rank : 1470)	NC score	0.103721 (rank : 929)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	118
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TMCC1_MOUSE
θ value	θ > 10 (rank : 1471)	NC score	0.095851 (rank : 1003)
Query Neighborhood Hits	457	Target Neighborhood Hits	315	Shared Neighborhood Hits	117
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TMCC3_HUMAN
θ value	θ > 10 (rank : 1472)	NC score	0.061797 (rank : 1353)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TMCC3_MOUSE
θ value	θ > 10 (rank : 1473)	NC score	0.054360 (rank : 1460)
Query Neighborhood Hits	457	Target Neighborhood Hits	192	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TMCO3_HUMAN
θ value	θ > 10 (rank : 1474)	NC score	0.111867 (rank : 867)
Query Neighborhood Hits	457	Target Neighborhood Hits	238	Shared Neighborhood Hits	102
SwissProt Accessions	Q6UWJ1, Q5JSB1, Q6NUN1, Q8NG29, Q8TCI6, Q96EA6, Q9NWT2	Gene names	TMCO3, C13orf11
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor (Putative LAG1-interacting protein).

TMCO3_MOUSE
θ value	θ > 10 (rank : 1475)	NC score	0.102323 (rank : 945)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BH01, Q3UFX1, Q7TMT5, Q8BGL4, Q8R303	Gene names	Tmco3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor.

TNIK_HUMAN
θ value	θ > 10 (rank : 1476)	NC score	0.064281 (rank : 1313)
Query Neighborhood Hits	457	Target Neighborhood Hits	1570	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TNIP3_HUMAN
θ value	θ > 10 (rank : 1477)	NC score	0.218075 (rank : 398)
Query Neighborhood Hits	457	Target Neighborhood Hits	511	Shared Neighborhood Hits	156
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TNNT1_HUMAN
θ value	θ > 10 (rank : 1478)	NC score	0.068637 (rank : 1263)
Query Neighborhood Hits	457	Target Neighborhood Hits	211	Shared Neighborhood Hits	77
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

TNNT1_MOUSE
θ value	θ > 10 (rank : 1479)	NC score	0.084827 (rank : 1092)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	91
SwissProt Accessions	O88346, O88795, Q9QUP7	Gene names	Tnnt1
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

TNNT2_HUMAN
θ value	θ > 10 (rank : 1480)	NC score	0.136948 (rank : 721)
Query Neighborhood Hits	457	Target Neighborhood Hits	433	Shared Neighborhood Hits	133
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TNNT2_MOUSE
θ value	θ > 10 (rank : 1481)	NC score	0.127615 (rank : 774)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	126
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TNNT3_HUMAN
θ value	θ > 10 (rank : 1482)	NC score	0.135645 (rank : 728)
Query Neighborhood Hits	457	Target Neighborhood Hits	327	Shared Neighborhood Hits	117
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TNNT3_MOUSE
θ value	θ > 10 (rank : 1483)	NC score	0.135997 (rank : 725)
Query Neighborhood Hits	457	Target Neighborhood Hits	317	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TPM2_HUMAN
θ value	θ > 10 (rank : 1484)	NC score	0.222174 (rank : 382)
Query Neighborhood Hits	457	Target Neighborhood Hits	677	Shared Neighborhood Hits	172
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 1485)	NC score	0.220921 (rank : 388)
Query Neighborhood Hits	457	Target Neighborhood Hits	676	Shared Neighborhood Hits	172
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM4_HUMAN
θ value	θ > 10 (rank : 1486)	NC score	0.216974 (rank : 405)
Query Neighborhood Hits	457	Target Neighborhood Hits	525	Shared Neighborhood Hits	160
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TPM4_MOUSE
θ value	θ > 10 (rank : 1487)	NC score	0.228098 (rank : 359)
Query Neighborhood Hits	457	Target Neighborhood Hits	703	Shared Neighborhood Hits	197
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPR_HUMAN
θ value	θ > 10 (rank : 1488)	NC score	0.266695 (rank : 208)
Query Neighborhood Hits	457	Target Neighborhood Hits	1921	Shared Neighborhood Hits	258
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TPX2_HUMAN
θ value	θ > 10 (rank : 1489)	NC score	0.050417 (rank : 1518)
Query Neighborhood Hits	457	Target Neighborhood Hits	150	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

TR150_MOUSE
θ value	θ > 10 (rank : 1490)	NC score	0.057074 (rank : 1416)
Query Neighborhood Hits	457	Target Neighborhood Hits	468	Shared Neighborhood Hits	76
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRAF3_HUMAN
θ value	θ > 10 (rank : 1491)	NC score	0.092852 (rank : 1024)
Query Neighborhood Hits	457	Target Neighborhood Hits	463	Shared Neighborhood Hits	124
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 1492)	NC score	0.092042 (rank : 1029)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	125
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF5_HUMAN
θ value	θ > 10 (rank : 1493)	NC score	0.072993 (rank : 1220)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	111
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 1494)	NC score	0.056773 (rank : 1424)
Query Neighborhood Hits	457	Target Neighborhood Hits	355	Shared Neighborhood Hits	81
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAIP_HUMAN
θ value	θ > 10 (rank : 1495)	NC score	0.232139 (rank : 337)
Query Neighborhood Hits	457	Target Neighborhood Hits	780	Shared Neighborhood Hits	189
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 1496)	NC score	0.232319 (rank : 335)
Query Neighborhood Hits	457	Target Neighborhood Hits	745	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRAK1_HUMAN
θ value	θ > 10 (rank : 1497)	NC score	0.221641 (rank : 385)
Query Neighborhood Hits	457	Target Neighborhood Hits	660	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TRAK2_HUMAN
θ value	θ > 10 (rank : 1498)	NC score	0.195605 (rank : 491)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	157
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TRIM8_HUMAN
θ value	θ > 10 (rank : 1499)	NC score	0.076135 (rank : 1187)
Query Neighborhood Hits	457	Target Neighborhood Hits	650	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 1500)	NC score	0.065266 (rank : 1300)
Query Neighborhood Hits	457	Target Neighborhood Hits	674	Shared Neighborhood Hits	143
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIO_HUMAN
θ value	θ > 10 (rank : 1501)	NC score	0.087363 (rank : 1068)
Query Neighborhood Hits	457	Target Neighborhood Hits	1580	Shared Neighborhood Hits	202
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TRIPB_HUMAN
θ value	θ > 10 (rank : 1502)	NC score	0.279779 (rank : 154)
Query Neighborhood Hits	457	Target Neighborhood Hits	1587	Shared Neighborhood Hits	259
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TS101_HUMAN
θ value	θ > 10 (rank : 1503)	NC score	0.118338 (rank : 830)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	116
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TS101_MOUSE
θ value	θ > 10 (rank : 1504)	NC score	0.109865 (rank : 881)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	108
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TSC1_HUMAN
θ value	θ > 10 (rank : 1505)	NC score	0.231766 (rank : 339)
Query Neighborhood Hits	457	Target Neighborhood Hits	765	Shared Neighborhood Hits	171
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TSKS_HUMAN
θ value	θ > 10 (rank : 1506)	NC score	0.064121 (rank : 1318)
Query Neighborhood Hits	457	Target Neighborhood Hits	220	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

TTC14_HUMAN
θ value	θ > 10 (rank : 1507)	NC score	0.112471 (rank : 863)
Query Neighborhood Hits	457	Target Neighborhood Hits	274	Shared Neighborhood Hits	87
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TTC1_HUMAN
θ value	θ > 10 (rank : 1508)	NC score	0.074187 (rank : 1209)
Query Neighborhood Hits	457	Target Neighborhood Hits	417	Shared Neighborhood Hits	104
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TUFT1_HUMAN
θ value	θ > 10 (rank : 1509)	NC score	0.235643 (rank : 316)
Query Neighborhood Hits	457	Target Neighborhood Hits	686	Shared Neighborhood Hits	190
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 1510)	NC score	0.234179 (rank : 321)
Query Neighborhood Hits	457	Target Neighborhood Hits	732	Shared Neighborhood Hits	193
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TXD11_HUMAN
θ value	θ > 10 (rank : 1511)	NC score	0.102909 (rank : 939)
Query Neighborhood Hits	457	Target Neighborhood Hits	402	Shared Neighborhood Hits	104
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TXK_HUMAN
θ value	θ > 10 (rank : 1512)	NC score	0.080404 (rank : 1138)
Query Neighborhood Hits	457	Target Neighborhood Hits	971	Shared Neighborhood Hits	121
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1513)	NC score	0.087309 (rank : 1070)
Query Neighborhood Hits	457	Target Neighborhood Hits	980	Shared Neighborhood Hits	132
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TXLNA_HUMAN
θ value	θ > 10 (rank : 1514)	NC score	0.196363 (rank : 484)
Query Neighborhood Hits	457	Target Neighborhood Hits	982	Shared Neighborhood Hits	188
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNA_MOUSE
θ value	θ > 10 (rank : 1515)	NC score	0.203303 (rank : 458)
Query Neighborhood Hits	457	Target Neighborhood Hits	846	Shared Neighborhood Hits	179
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNB_HUMAN
θ value	θ > 10 (rank : 1516)	NC score	0.171926 (rank : 563)
Query Neighborhood Hits	457	Target Neighborhood Hits	912	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TXLNB_MOUSE
θ value	θ > 10 (rank : 1517)	NC score	0.177466 (rank : 550)
Query Neighborhood Hits	457	Target Neighborhood Hits	640	Shared Neighborhood Hits	150
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TXLNG_MOUSE
θ value	θ > 10 (rank : 1518)	NC score	0.188412 (rank : 512)
Query Neighborhood Hits	457	Target Neighborhood Hits	552	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

TXND2_MOUSE
θ value	θ > 10 (rank : 1519)	NC score	0.098556 (rank : 979)
Query Neighborhood Hits	457	Target Neighborhood Hits	828	Shared Neighborhood Hits	131
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

U2AFL_HUMAN
θ value	θ > 10 (rank : 1520)	NC score	0.110251 (rank : 878)
Query Neighborhood Hits	457	Target Neighborhood Hits	503	Shared Neighborhood Hits	142
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

U2AFL_MOUSE
θ value	θ > 10 (rank : 1521)	NC score	0.076663 (rank : 1182)
Query Neighborhood Hits	457	Target Neighborhood Hits	389	Shared Neighborhood Hits	102
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

U2AFM_HUMAN
θ value	θ > 10 (rank : 1522)	NC score	0.112582 (rank : 862)
Query Neighborhood Hits	457	Target Neighborhood Hits	577	Shared Neighborhood Hits	150
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

U2AFM_MOUSE
θ value	θ > 10 (rank : 1523)	NC score	0.115809 (rank : 846)
Query Neighborhood Hits	457	Target Neighborhood Hits	543	Shared Neighborhood Hits	143
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

UBXD2_HUMAN
θ value	θ > 10 (rank : 1524)	NC score	0.060178 (rank : 1368)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	68
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

UN84A_HUMAN
θ value	θ > 10 (rank : 1525)	NC score	0.068748 (rank : 1262)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	76
SwissProt Accessions	O94901, Q96CZ7, Q9HA14, Q9UH98	Gene names	UNC84A, KIAA0810, SUN1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

UN84B_MOUSE
θ value	θ > 10 (rank : 1526)	NC score	0.066776 (rank : 1286)
Query Neighborhood Hits	457	Target Neighborhood Hits	194	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BJS4	Gene names	Unc84b, Sun2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2.

UT14A_MOUSE
θ value	θ > 10 (rank : 1527)	NC score	0.056267 (rank : 1428)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	65
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

UT14C_HUMAN
θ value	θ > 10 (rank : 1528)	NC score	0.057222 (rank : 1413)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	68
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

UTP11_HUMAN
θ value	θ > 10 (rank : 1529)	NC score	0.055303 (rank : 1445)
Query Neighborhood Hits	457	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y3A2, Q5VT93, Q9BS98, Q9NS31	Gene names	UTP11L
Domain Architecture
Description	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA- associated protein 11) (UTP11-like protein).

UTRO_HUMAN
θ value	θ > 10 (rank : 1530)	NC score	0.204053 (rank : 457)
Query Neighborhood Hits	457	Target Neighborhood Hits	960	Shared Neighborhood Hits	197
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

UVRAG_HUMAN
θ value	θ > 10 (rank : 1531)	NC score	0.067169 (rank : 1281)
Query Neighborhood Hits	457	Target Neighborhood Hits	150	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

VDP_HUMAN
θ value	θ > 10 (rank : 1532)	NC score	0.208838 (rank : 440)
Query Neighborhood Hits	457	Target Neighborhood Hits	645	Shared Neighborhood Hits	172
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VDP_MOUSE
θ value	θ > 10 (rank : 1533)	NC score	0.174591 (rank : 556)
Query Neighborhood Hits	457	Target Neighborhood Hits	469	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VIME_HUMAN
θ value	θ > 10 (rank : 1534)	NC score	0.130375 (rank : 763)
Query Neighborhood Hits	457	Target Neighborhood Hits	706	Shared Neighborhood Hits	182
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

VIME_MOUSE
θ value	θ > 10 (rank : 1535)	NC score	0.134778 (rank : 733)
Query Neighborhood Hits	457	Target Neighborhood Hits	716	Shared Neighborhood Hits	184
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

VINC_HUMAN
θ value	θ > 10 (rank : 1536)	NC score	0.064549 (rank : 1308)
Query Neighborhood Hits	457	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	θ > 10 (rank : 1537)	NC score	0.052133 (rank : 1498)
Query Neighborhood Hits	457	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

WDR60_MOUSE
θ value	θ > 10 (rank : 1538)	NC score	0.083993 (rank : 1101)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

WDR67_HUMAN
θ value	θ > 10 (rank : 1539)	NC score	0.176833 (rank : 551)
Query Neighborhood Hits	457	Target Neighborhood Hits	782	Shared Neighborhood Hits	173
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

WDR67_MOUSE
θ value	θ > 10 (rank : 1540)	NC score	0.116005 (rank : 844)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	126
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

WTAP_HUMAN
θ value	θ > 10 (rank : 1541)	NC score	0.120466 (rank : 809)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	92
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

WTAP_MOUSE
θ value	θ > 10 (rank : 1542)	NC score	0.118930 (rank : 824)
Query Neighborhood Hits	457	Target Neighborhood Hits	250	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

WWC1_HUMAN
θ value	θ > 10 (rank : 1543)	NC score	0.068378 (rank : 1266)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 1544)	NC score	0.058767 (rank : 1387)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	78
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWC3_HUMAN
θ value	θ > 10 (rank : 1545)	NC score	0.061756 (rank : 1355)
Query Neighborhood Hits	457	Target Neighborhood Hits	193	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

XE7_HUMAN
θ value	θ > 10 (rank : 1546)	NC score	0.208142 (rank : 444)
Query Neighborhood Hits	457	Target Neighborhood Hits	738	Shared Neighborhood Hits	184
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

XL3A_MOUSE
θ value	θ > 10 (rank : 1547)	NC score	0.090514 (rank : 1042)
Query Neighborhood Hits	457	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

XL3B_MOUSE
θ value	θ > 10 (rank : 1548)	NC score	0.099978 (rank : 961)
Query Neighborhood Hits	457	Target Neighborhood Hits	146	Shared Neighborhood Hits	74
SwissProt Accessions	Q61806, Q61244	Gene names	Xlr3b
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A (XLR-related protein A12).

XRCC4_HUMAN
θ value	θ > 10 (rank : 1549)	NC score	0.060122 (rank : 1370)
Query Neighborhood Hits	457	Target Neighborhood Hits	131	Shared Neighborhood Hits	50
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

YO11_MOUSE
θ value	θ > 10 (rank : 1550)	NC score	0.191330 (rank : 501)
Query Neighborhood Hits	457	Target Neighborhood Hits	272	Shared Neighborhood Hits	114
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

YTDC1_HUMAN
θ value	θ > 10 (rank : 1551)	NC score	0.057783 (rank : 1406)
Query Neighborhood Hits	457	Target Neighborhood Hits	458	Shared Neighborhood Hits	80
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZAP70_HUMAN
θ value	θ > 10 (rank : 1552)	NC score	0.051644 (rank : 1504)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	66
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1553)	NC score	0.052405 (rank : 1495)
Query Neighborhood Hits	457	Target Neighborhood Hits	905	Shared Neighborhood Hits	66
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZC11A_MOUSE
θ value	θ > 10 (rank : 1554)	NC score	0.056213 (rank : 1429)
Query Neighborhood Hits	457	Target Neighborhood Hits	216	Shared Neighborhood Hits	50
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZN291_HUMAN
θ value	θ > 10 (rank : 1555)	NC score	0.212602 (rank : 424)
Query Neighborhood Hits	457	Target Neighborhood Hits	647	Shared Neighborhood Hits	171
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ZN318_HUMAN
θ value	θ > 10 (rank : 1556)	NC score	0.079397 (rank : 1152)
Query Neighborhood Hits	457	Target Neighborhood Hits	497	Shared Neighborhood Hits	125
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ZN318_MOUSE
θ value	θ > 10 (rank : 1557)	NC score	0.119887 (rank : 816)
Query Neighborhood Hits	457	Target Neighborhood Hits	642	Shared Neighborhood Hits	152
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN365_HUMAN
θ value	θ > 10 (rank : 1558)	NC score	0.053134 (rank : 1483)
Query Neighborhood Hits	457	Target Neighborhood Hits	145	Shared Neighborhood Hits	57
SwissProt Accessions	Q70YC5, O94930, Q5HYE6, Q68SG8, Q6NSK2, Q6P9D4, Q70YC6, Q70YC7	Gene names	ZNF365, KIAA0844
Domain Architecture	No domain graphic available
Description	Protein ZNF365.

ZN365_MOUSE
θ value	θ > 10 (rank : 1559)	NC score	0.067494 (rank : 1276)
Query Neighborhood Hits	457	Target Neighborhood Hits	193	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BG89, Q80TQ4, Q8BK39, Q8BXT2	Gene names	Znf365, Kiaa0844, Zfp365
Domain Architecture	No domain graphic available
Description	Protein ZNF365 (Su48).

ZN638_HUMAN
θ value	θ > 10 (rank : 1560)	NC score	0.057042 (rank : 1419)
Query Neighborhood Hits	457	Target Neighborhood Hits	343	Shared Neighborhood Hits	78
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ZRF1_HUMAN
θ value	θ > 10 (rank : 1561)	NC score	0.135131 (rank : 732)
Query Neighborhood Hits	457	Target Neighborhood Hits	457	Shared Neighborhood Hits	127
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

ZRF1_MOUSE
θ value	θ > 10 (rank : 1562)	NC score	0.143669 (rank : 686)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	122
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

ZWINT_HUMAN
θ value	θ > 10 (rank : 1563)	NC score	0.144452 (rank : 681)
Query Neighborhood Hits	457	Target Neighborhood Hits	333	Shared Neighborhood Hits	120
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

ZWINT_MOUSE
θ value	θ > 10 (rank : 1564)	NC score	0.209548 (rank : 435)
Query Neighborhood Hits	457	Target Neighborhood Hits	497	Shared Neighborhood Hits	161
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

Hits sorted by NC score

NEBL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	457	Target Neighborhood Hits	457	Shared Neighborhood Hits	457
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
NC score	0.815639 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	457	Target Neighborhood Hits	420	Shared Neighborhood Hits	232
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

LASP1_MOUSE
NC score	0.647617 (rank : 3)	θ value	1.4233e-29 (rank : 5)
Query Neighborhood Hits	457	Target Neighborhood Hits	297	Shared Neighborhood Hits	171
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_HUMAN
NC score	0.644977 (rank : 4)	θ value	3.28125e-26 (rank : 6)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	171
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

NRAP_MOUSE
NC score	0.529674 (rank : 5)	θ value	5.55816e-50 (rank : 3)
Query Neighborhood Hits	457	Target Neighborhood Hits	167	Shared Neighborhood Hits	39
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

VINEX_HUMAN
NC score	0.526463 (rank : 6)	θ value	9.59137e-10 (rank : 10)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	172
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

SRBS1_HUMAN
NC score	0.521906 (rank : 7)	θ value	9.59137e-10 (rank : 9)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	197
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NRAP_HUMAN
NC score	0.521289 (rank : 8)	θ value	3.37202e-47 (rank : 4)
Query Neighborhood Hits	457	Target Neighborhood Hits	159	Shared Neighborhood Hits	29
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

VINEX_MOUSE
NC score	0.520792 (rank : 9)	θ value	8.11959e-09 (rank : 13)
Query Neighborhood Hits	457	Target Neighborhood Hits	286	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRC8_HUMAN
NC score	0.516506 (rank : 10)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	457	Target Neighborhood Hits	269	Shared Neighborhood Hits	170
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRBS1_MOUSE
NC score	0.512886 (rank : 11)	θ value	2.79066e-09 (rank : 11)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	184
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_MOUSE
NC score	0.511931 (rank : 12)	θ value	4.76016e-09 (rank : 12)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	168
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

PPIP1_MOUSE
NC score	0.500228 (rank : 13)	θ value	7.59969e-07 (rank : 19)
Query Neighborhood Hits	457	Target Neighborhood Hits	377	Shared Neighborhood Hits	238
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PPIP1_HUMAN
NC score	0.496457 (rank : 14)	θ value	1.69304e-06 (rank : 25)
Query Neighborhood Hits	457	Target Neighborhood Hits	389	Shared Neighborhood Hits	242
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PACN2_MOUSE
NC score	0.489192 (rank : 15)	θ value	9.92553e-07 (rank : 21)
Query Neighborhood Hits	457	Target Neighborhood Hits	382	Shared Neighborhood Hits	219
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_HUMAN
NC score	0.486193 (rank : 16)	θ value	2.21117e-06 (rank : 29)
Query Neighborhood Hits	457	Target Neighborhood Hits	339	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

HCLS1_MOUSE
NC score	0.483495 (rank : 17)	θ value	6.43352e-06 (rank : 35)
Query Neighborhood Hits	457	Target Neighborhood Hits	329	Shared Neighborhood Hits	156
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PACN3_MOUSE
NC score	0.481321 (rank : 18)	θ value	1.99992e-07 (rank : 17)
Query Neighborhood Hits	457	Target Neighborhood Hits	380	Shared Neighborhood Hits	225
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PACN3_HUMAN
NC score	0.480821 (rank : 19)	θ value	1.99992e-07 (rank : 16)
Query Neighborhood Hits	457	Target Neighborhood Hits	385	Shared Neighborhood Hits	220
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

ABI2_MOUSE
NC score	0.477560 (rank : 20)	θ value	2.21117e-06 (rank : 27)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	159
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

HCLS1_HUMAN
NC score	0.477255 (rank : 21)	θ value	1.43324e-05 (rank : 42)
Query Neighborhood Hits	457	Target Neighborhood Hits	358	Shared Neighborhood Hits	152
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

PACN1_HUMAN
NC score	0.477100 (rank : 22)	θ value	1.69304e-06 (rank : 24)
Query Neighborhood Hits	457	Target Neighborhood Hits	320	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

SH3G2_HUMAN
NC score	0.472726 (rank : 23)	θ value	1.87187e-05 (rank : 44)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	198
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

ABI1_MOUSE
NC score	0.471042 (rank : 24)	θ value	2.88788e-06 (rank : 30)
Query Neighborhood Hits	457	Target Neighborhood Hits	246	Shared Neighborhood Hits	155
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
NC score	0.471031 (rank : 25)	θ value	2.21117e-06 (rank : 26)
Query Neighborhood Hits	457	Target Neighborhood Hits	350	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CD2AP_MOUSE
NC score	0.470231 (rank : 26)	θ value	0.000158464 (rank : 71)
Query Neighborhood Hits	457	Target Neighborhood Hits	336	Shared Neighborhood Hits	187
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

DBNL_HUMAN
NC score	0.469741 (rank : 27)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	457	Target Neighborhood Hits	244	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

PACN1_MOUSE
NC score	0.468156 (rank : 28)	θ value	3.77169e-06 (rank : 31)
Query Neighborhood Hits	457	Target Neighborhood Hits	283	Shared Neighborhood Hits	183
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

CD2AP_HUMAN
NC score	0.467363 (rank : 29)	θ value	0.000602161 (rank : 91)
Query Neighborhood Hits	457	Target Neighborhood Hits	315	Shared Neighborhood Hits	185
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

DBNL_MOUSE
NC score	0.466310 (rank : 30)	θ value	4.45536e-07 (rank : 18)
Query Neighborhood Hits	457	Target Neighborhood Hits	306	Shared Neighborhood Hits	161
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

SH3K1_HUMAN
NC score	0.463431 (rank : 31)	θ value	0.000602161 (rank : 95)
Query Neighborhood Hits	457	Target Neighborhood Hits	341	Shared Neighborhood Hits	189
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3G2_MOUSE
NC score	0.463409 (rank : 32)	θ value	3.19293e-05 (rank : 51)
Query Neighborhood Hits	457	Target Neighborhood Hits	319	Shared Neighborhood Hits	192
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3K1_MOUSE
NC score	0.462163 (rank : 33)	θ value	0.000602161 (rank : 96)
Query Neighborhood Hits	457	Target Neighborhood Hits	332	Shared Neighborhood Hits	195
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3G3_MOUSE
NC score	0.460636 (rank : 34)	θ value	3.19293e-05 (rank : 52)
Query Neighborhood Hits	457	Target Neighborhood Hits	236	Shared Neighborhood Hits	165
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

ABI1_HUMAN
NC score	0.455136 (rank : 35)	θ value	8.40245e-06 (rank : 37)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

SH3G3_HUMAN
NC score	0.449443 (rank : 36)	θ value	4.1701e-05 (rank : 53)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	163
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_HUMAN
NC score	0.448601 (rank : 37)	θ value	0.000602161 (rank : 94)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	196
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
NC score	0.440673 (rank : 38)	θ value	0.00035302 (rank : 84)
Query Neighborhood Hits	457	Target Neighborhood Hits	291	Shared Neighborhood Hits	181
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ITSN2_MOUSE
NC score	0.438100 (rank : 39)	θ value	8.40245e-06 (rank : 38)
Query Neighborhood Hits	457	Target Neighborhood Hits	1371	Shared Neighborhood Hits	370
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN1_MOUSE
NC score	0.433608 (rank : 40)	θ value	0.000121331 (rank : 70)
Query Neighborhood Hits	457	Target Neighborhood Hits	1669	Shared Neighborhood Hits	393
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.432985 (rank : 41)	θ value	0.000158464 (rank : 74)
Query Neighborhood Hits	457	Target Neighborhood Hits	1757	Shared Neighborhood Hits	389
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NCF2_HUMAN
NC score	0.431297 (rank : 42)	θ value	0.125558 (rank : 239)
Query Neighborhood Hits	457	Target Neighborhood Hits	229	Shared Neighborhood Hits	154
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

ITSN2_HUMAN
NC score	0.430165 (rank : 43)	θ value	1.43324e-05 (rank : 43)
Query Neighborhood Hits	457	Target Neighborhood Hits	1173	Shared Neighborhood Hits	337
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

GRB2_HUMAN
NC score	0.410450 (rank : 44)	θ value	2.21117e-06 (rank : 28)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	163
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

NCF4_MOUSE
NC score	0.409658 (rank : 45)	θ value	0.00869519 (rank : 158)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	136
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

GRB2_MOUSE
NC score	0.409467 (rank : 46)	θ value	1.69304e-06 (rank : 22)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	163
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

ABI3_HUMAN
NC score	0.405347 (rank : 47)	θ value	0.00665767 (rank : 145)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	131
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
NC score	0.404301 (rank : 48)	θ value	0.00509761 (rank : 135)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	130
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

GRAP2_MOUSE
NC score	0.404246 (rank : 49)	θ value	0.000158464 (rank : 73)
Query Neighborhood Hits	457	Target Neighborhood Hits	297	Shared Neighborhood Hits	162
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

ARHG7_MOUSE
NC score	0.396352 (rank : 50)	θ value	0.000461057 (rank : 87)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	222
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

GRAP2_HUMAN
NC score	0.393401 (rank : 51)	θ value	0.00134147 (rank : 106)
Query Neighborhood Hits	457	Target Neighborhood Hits	304	Shared Neighborhood Hits	160
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

NCF4_HUMAN
NC score	0.385558 (rank : 52)	θ value	0.0193708 (rank : 175)
Query Neighborhood Hits	457	Target Neighborhood Hits	161	Shared Neighborhood Hits	123
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

GRAP_MOUSE
NC score	0.383966 (rank : 53)	θ value	0.00509761 (rank : 142)
Query Neighborhood Hits	457	Target Neighborhood Hits	309	Shared Neighborhood Hits	164
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ARHG7_HUMAN
NC score	0.383133 (rank : 54)	θ value	1.09739e-05 (rank : 39)
Query Neighborhood Hits	457	Target Neighborhood Hits	347	Shared Neighborhood Hits	183
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

GRAP_HUMAN
NC score	0.382714 (rank : 55)	θ value	0.000461057 (rank : 88)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	159
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ARHG6_MOUSE
NC score	0.376367 (rank : 56)	θ value	0.00509761 (rank : 139)
Query Neighborhood Hits	457	Target Neighborhood Hits	394	Shared Neighborhood Hits	216
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

CRKL_HUMAN
NC score	0.374840 (rank : 57)	θ value	0.000270298 (rank : 77)
Query Neighborhood Hits	457	Target Neighborhood Hits	313	Shared Neighborhood Hits	151
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

NCK1_HUMAN
NC score	0.371844 (rank : 58)	θ value	0.0252991 (rank : 180)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	163
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

CRKL_MOUSE
NC score	0.370229 (rank : 59)	θ value	0.000270298 (rank : 78)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	148
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

ARHG6_HUMAN
NC score	0.368200 (rank : 60)	θ value	0.00509761 (rank : 138)
Query Neighborhood Hits	457	Target Neighborhood Hits	376	Shared Neighborhood Hits	212
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

DNMBP_HUMAN
NC score	0.366826 (rank : 61)	θ value	0.00390308 (rank : 125)
Query Neighborhood Hits	457	Target Neighborhood Hits	413	Shared Neighborhood Hits	203
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

NCK2_HUMAN
NC score	0.364596 (rank : 62)	θ value	0.163984 (rank : 250)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	163
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

STAC_HUMAN
NC score	0.363217 (rank : 63)	θ value	0.00175202 (rank : 113)
Query Neighborhood Hits	457	Target Neighborhood Hits	276	Shared Neighborhood Hits	152
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NCF1_MOUSE
NC score	0.362506 (rank : 64)	θ value	0.0113563 (rank : 166)
Query Neighborhood Hits	457	Target Neighborhood Hits	198	Shared Neighborhood Hits	146
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF1_HUMAN
NC score	0.361664 (rank : 65)	θ value	0.00869519 (rank : 157)
Query Neighborhood Hits	457	Target Neighborhood Hits	198	Shared Neighborhood Hits	143
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

STAC_MOUSE
NC score	0.356590 (rank : 66)	θ value	0.00228821 (rank : 119)
Query Neighborhood Hits	457	Target Neighborhood Hits	268	Shared Neighborhood Hits	150
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

DNMBP_MOUSE
NC score	0.356142 (rank : 67)	θ value	0.00390308 (rank : 126)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	197
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

OSTF1_HUMAN
NC score	0.354115 (rank : 68)	θ value	7.1131e-05 (rank : 67)
Query Neighborhood Hits	457	Target Neighborhood Hits	466	Shared Neighborhood Hits	167
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

STAM2_MOUSE
NC score	0.353203 (rank : 69)	θ value	0.00298849 (rank : 124)
Query Neighborhood Hits	457	Target Neighborhood Hits	285	Shared Neighborhood Hits	160
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STAM1_MOUSE
NC score	0.352740 (rank : 70)	θ value	θ > 10 (rank : 1382)
Query Neighborhood Hits	457	Target Neighborhood Hits	273	Shared Neighborhood Hits	153
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

PEX13_HUMAN
NC score	0.347716 (rank : 71)	θ value	0.000786445 (rank : 99)
Query Neighborhood Hits	457	Target Neighborhood Hits	128	Shared Neighborhood Hits	106
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

OSTF1_MOUSE
NC score	0.347425 (rank : 72)	θ value	5.44631e-05 (rank : 60)
Query Neighborhood Hits	457	Target Neighborhood Hits	467	Shared Neighborhood Hits	167
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

STAM1_HUMAN
NC score	0.347272 (rank : 73)	θ value	θ > 10 (rank : 1381)
Query Neighborhood Hits	457	Target Neighborhood Hits	271	Shared Neighborhood Hits	153
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CRK_MOUSE
NC score	0.346314 (rank : 74)	θ value	0.0330416 (rank : 184)
Query Neighborhood Hits	457	Target Neighborhood Hits	314	Shared Neighborhood Hits	155
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

STAM2_HUMAN
NC score	0.343800 (rank : 75)	θ value	0.00869519 (rank : 159)
Query Neighborhood Hits	457	Target Neighborhood Hits	288	Shared Neighborhood Hits	160
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

CRK_HUMAN
NC score	0.343403 (rank : 76)	θ value	0.0330416 (rank : 183)
Query Neighborhood Hits	457	Target Neighborhood Hits	308	Shared Neighborhood Hits	155
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NPHP1_MOUSE
NC score	0.342357 (rank : 77)	θ value	0.00390308 (rank : 131)
Query Neighborhood Hits	457	Target Neighborhood Hits	267	Shared Neighborhood Hits	163
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

PEX13_MOUSE
NC score	0.338802 (rank : 78)	θ value	0.00390308 (rank : 132)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

VAV_HUMAN
NC score	0.329059 (rank : 79)	θ value	0.000786445 (rank : 101)
Query Neighborhood Hits	457	Target Neighborhood Hits	452	Shared Neighborhood Hits	177
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
NC score	0.325971 (rank : 80)	θ value	0.00228821 (rank : 120)
Query Neighborhood Hits	457	Target Neighborhood Hits	430	Shared Neighborhood Hits	173
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

SPTA2_HUMAN
NC score	0.313303 (rank : 81)	θ value	1.81305 (rank : 356)
Query Neighborhood Hits	457	Target Neighborhood Hits	888	Shared Neighborhood Hits	318
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

RAD50_HUMAN
NC score	0.312894 (rank : 82)	θ value	0.00035302 (rank : 83)
Query Neighborhood Hits	457	Target Neighborhood Hits	1317	Shared Neighborhood Hits	248
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
NC score	0.310916 (rank : 83)	θ value	0.00102713 (rank : 104)
Query Neighborhood Hits	457	Target Neighborhood Hits	1366	Shared Neighborhood Hits	250
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

ERC2_MOUSE
NC score	0.310839 (rank : 84)	θ value	7.34386e-10 (rank : 8)
Query Neighborhood Hits	457	Target Neighborhood Hits	1166	Shared Neighborhood Hits	235
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

EEA1_MOUSE
NC score	0.309423 (rank : 85)	θ value	4.0297e-08 (rank : 15)
Query Neighborhood Hits	457	Target Neighborhood Hits	1637	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

VAV2_MOUSE
NC score	0.308714 (rank : 86)	θ value	0.00869519 (rank : 160)
Query Neighborhood Hits	457	Target Neighborhood Hits	456	Shared Neighborhood Hits	172
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

PIBF1_HUMAN
NC score	0.308123 (rank : 87)	θ value	5.44631e-05 (rank : 61)
Query Neighborhood Hits	457	Target Neighborhood Hits	1041	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

RIMB1_MOUSE
NC score	0.307747 (rank : 88)	θ value	2.36792 (rank : 373)
Query Neighborhood Hits	457	Target Neighborhood Hits	1376	Shared Neighborhood Hits	332
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

KTN1_MOUSE
NC score	0.307583 (rank : 89)	θ value	7.1131e-05 (rank : 64)
Query Neighborhood Hits	457	Target Neighborhood Hits	1324	Shared Neighborhood Hits	241
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

VAV2_HUMAN
NC score	0.307049 (rank : 90)	θ value	0.0148317 (rank : 172)
Query Neighborhood Hits	457	Target Neighborhood Hits	453	Shared Neighborhood Hits	174
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

EEA1_HUMAN
NC score	0.305105 (rank : 91)	θ value	1.2105e-12 (rank : 7)
Query Neighborhood Hits	457	Target Neighborhood Hits	1796	Shared Neighborhood Hits	256
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RB6I2_MOUSE
NC score	0.303164 (rank : 92)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	457	Target Neighborhood Hits	1433	Shared Neighborhood Hits	245
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.302945 (rank : 93)	θ value	0.000270298 (rank : 80)
Query Neighborhood Hits	457	Target Neighborhood Hits	1584	Shared Neighborhood Hits	259
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CE290_HUMAN
NC score	0.302688 (rank : 94)	θ value	5.44631e-05 (rank : 54)
Query Neighborhood Hits	457	Target Neighborhood Hits	1553	Shared Neighborhood Hits	246
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SPTA1_HUMAN
NC score	0.301235 (rank : 95)	θ value	1.06291 (rank : 327)
Query Neighborhood Hits	457	Target Neighborhood Hits	748	Shared Neighborhood Hits	302
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

STS2_HUMAN
NC score	0.300815 (rank : 96)	θ value	2.44474e-05 (rank : 50)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SYCP1_HUMAN
NC score	0.299882 (rank : 97)	θ value	5.44631e-05 (rank : 63)
Query Neighborhood Hits	457	Target Neighborhood Hits	1313	Shared Neighborhood Hits	242
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SMC1A_MOUSE
NC score	0.299526 (rank : 98)	θ value	1.87187e-05 (rank : 45)
Query Neighborhood Hits	457	Target Neighborhood Hits	1384	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

STAC3_MOUSE
NC score	0.299263 (rank : 99)	θ value	5.27518 (rank : 415)
Query Neighborhood Hits	457	Target Neighborhood Hits	232	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

MYO1F_HUMAN
NC score	0.298703 (rank : 100)	θ value	0.00175202 (rank : 112)
Query Neighborhood Hits	457	Target Neighborhood Hits	275	Shared Neighborhood Hits	176
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
NC score	0.298319 (rank : 101)	θ value	0.00298849 (rank : 122)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	175
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

SMC2_HUMAN
NC score	0.298056 (rank : 102)	θ value	0.0961366 (rank : 228)
Query Neighborhood Hits	457	Target Neighborhood Hits	1405	Shared Neighborhood Hits	259
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

STAC3_HUMAN
NC score	0.297894 (rank : 103)	θ value	5.27518 (rank : 414)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	134
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SYCP1_MOUSE
NC score	0.296457 (rank : 104)	θ value	0.00035302 (rank : 85)
Query Neighborhood Hits	457	Target Neighborhood Hits	1456	Shared Neighborhood Hits	254
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CCD46_HUMAN
NC score	0.295881 (rank : 105)	θ value	0.365318 (rank : 272)
Query Neighborhood Hits	457	Target Neighborhood Hits	1430	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SM1L2_HUMAN
NC score	0.295784 (rank : 106)	θ value	0.0736092 (rank : 214)
Query Neighborhood Hits	457	Target Neighborhood Hits	1019	Shared Neighborhood Hits	236
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

PLCG2_HUMAN
NC score	0.294283 (rank : 107)	θ value	0.00298849 (rank : 123)
Query Neighborhood Hits	457	Target Neighborhood Hits	280	Shared Neighborhood Hits	142
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

SMC1A_HUMAN
NC score	0.293797 (rank : 108)	θ value	5.44631e-05 (rank : 62)
Query Neighborhood Hits	457	Target Neighborhood Hits	1346	Shared Neighborhood Hits	252
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

MYO1E_HUMAN
NC score	0.293658 (rank : 109)	θ value	0.00035302 (rank : 82)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	182
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

PLCG1_MOUSE
NC score	0.293236 (rank : 110)	θ value	0.00665767 (rank : 150)
Query Neighborhood Hits	457	Target Neighborhood Hits	314	Shared Neighborhood Hits	151
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

GOGA4_HUMAN
NC score	0.292902 (rank : 111)	θ value	0.00390308 (rank : 128)
Query Neighborhood Hits	457	Target Neighborhood Hits	2034	Shared Neighborhood Hits	277
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

ERC2_HUMAN
NC score	0.292436 (rank : 112)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	457	Target Neighborhood Hits	1156	Shared Neighborhood Hits	231
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CCD46_MOUSE
NC score	0.292104 (rank : 113)	θ value	0.00509761 (rank : 141)
Query Neighborhood Hits	457	Target Neighborhood Hits	1405	Shared Neighborhood Hits	257
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

AHI1_MOUSE
NC score	0.291982 (rank : 114)	θ value	0.00175202 (rank : 110)
Query Neighborhood Hits	457	Target Neighborhood Hits	496	Shared Neighborhood Hits	159
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

SNX18_MOUSE
NC score	0.291661 (rank : 115)	θ value	0.0563607 (rank : 204)
Query Neighborhood Hits	457	Target Neighborhood Hits	198	Shared Neighborhood Hits	124
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

FLIP1_HUMAN
NC score	0.291532 (rank : 116)	θ value	0.00228821 (rank : 116)
Query Neighborhood Hits	457	Target Neighborhood Hits	1405	Shared Neighborhood Hits	254
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
NC score	0.290824 (rank : 117)	θ value	0.279714 (rank : 260)
Query Neighborhood Hits	457	Target Neighborhood Hits	1176	Shared Neighborhood Hits	230
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

AHI1_HUMAN
NC score	0.290039 (rank : 118)	θ value	0.00665767 (rank : 146)
Query Neighborhood Hits	457	Target Neighborhood Hits	537	Shared Neighborhood Hits	171
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CENPF_HUMAN
NC score	0.289572 (rank : 119)	θ value	0.0961366 (rank : 219)
Query Neighborhood Hits	457	Target Neighborhood Hits	1932	Shared Neighborhood Hits	272
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KTN1_HUMAN
NC score	0.289391 (rank : 120)	θ value	5.44631e-05 (rank : 57)
Query Neighborhood Hits	457	Target Neighborhood Hits	1197	Shared Neighborhood Hits	225
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYH13_HUMAN
NC score	0.288695 (rank : 121)	θ value	5.44631e-05 (rank : 58)
Query Neighborhood Hits	457	Target Neighborhood Hits	1504	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

GOGB1_HUMAN
NC score	0.288251 (rank : 122)	θ value	0.000786445 (rank : 97)
Query Neighborhood Hits	457	Target Neighborhood Hits	2297	Shared Neighborhood Hits	284
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CI093_HUMAN
NC score	0.287931 (rank : 123)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	457	Target Neighborhood Hits	1088	Shared Neighborhood Hits	235
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CP135_MOUSE
NC score	0.287761 (rank : 124)	θ value	0.279714 (rank : 258)
Query Neighborhood Hits	457	Target Neighborhood Hits	1278	Shared Neighborhood Hits	239
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SM1L2_MOUSE
NC score	0.287575 (rank : 125)	θ value	θ > 10 (rank : 1348)
Query Neighborhood Hits	457	Target Neighborhood Hits	918	Shared Neighborhood Hits	220
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

CI039_HUMAN
NC score	0.287572 (rank : 126)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	457	Target Neighborhood Hits	1171	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

SNX18_HUMAN
NC score	0.287096 (rank : 127)	θ value	0.0563607 (rank : 203)
Query Neighborhood Hits	457	Target Neighborhood Hits	207	Shared Neighborhood Hits	126
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

MYH1_MOUSE
NC score	0.286307 (rank : 128)	θ value	1.69304e-06 (rank : 23)
Query Neighborhood Hits	457	Target Neighborhood Hits	1461	Shared Neighborhood Hits	242
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

GCC2_MOUSE
NC score	0.285792 (rank : 129)	θ value	1.81305 (rank : 343)
Query Neighborhood Hits	457	Target Neighborhood Hits	1619	Shared Neighborhood Hits	252
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RBP24_HUMAN
NC score	0.285606 (rank : 130)	θ value	0.000158464 (rank : 76)
Query Neighborhood Hits	457	Target Neighborhood Hits	1559	Shared Neighborhood Hits	248
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.285453 (rank : 131)	θ value	0.000158464 (rank : 72)
Query Neighborhood Hits	457	Target Neighborhood Hits	1558	Shared Neighborhood Hits	250
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MY18A_MOUSE
NC score	0.285280 (rank : 132)	θ value	0.00298849 (rank : 121)
Query Neighborhood Hits	457	Target Neighborhood Hits	1989	Shared Neighborhood Hits	269
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD39_MOUSE
NC score	0.284715 (rank : 133)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	457	Target Neighborhood Hits	1026	Shared Neighborhood Hits	221
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

EFS_MOUSE
NC score	0.284111 (rank : 134)	θ value	0.163984 (rank : 246)
Query Neighborhood Hits	457	Target Neighborhood Hits	389	Shared Neighborhood Hits	135
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

MYH8_HUMAN
NC score	0.283870 (rank : 135)	θ value	0.00869519 (rank : 156)
Query Neighborhood Hits	457	Target Neighborhood Hits	1610	Shared Neighborhood Hits	264
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SMC2_MOUSE
NC score	0.283844 (rank : 136)	θ value	0.00665767 (rank : 153)
Query Neighborhood Hits	457	Target Neighborhood Hits	1131	Shared Neighborhood Hits	240
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

TAXB1_HUMAN
NC score	0.283666 (rank : 137)	θ value	θ > 10 (rank : 1441)
Query Neighborhood Hits	457	Target Neighborhood Hits	829	Shared Neighborhood Hits	212
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

CP135_HUMAN
NC score	0.283398 (rank : 138)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	457	Target Neighborhood Hits	1290	Shared Neighborhood Hits	240
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH8_MOUSE
NC score	0.283377 (rank : 139)	θ value	7.1131e-05 (rank : 66)
Query Neighborhood Hits	457	Target Neighborhood Hits	1600	Shared Neighborhood Hits	258
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH2_HUMAN
NC score	0.283044 (rank : 140)	θ value	7.1131e-05 (rank : 65)
Query Neighborhood Hits	457	Target Neighborhood Hits	1491	Shared Neighborhood Hits	243
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH4_MOUSE
NC score	0.282544 (rank : 141)	θ value	1.09739e-05 (rank : 40)
Query Neighborhood Hits	457	Target Neighborhood Hits	1476	Shared Neighborhood Hits	244
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

CT032_HUMAN
NC score	0.282447 (rank : 142)	θ value	0.365318 (rank : 275)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

MYH1_HUMAN
NC score	0.282369 (rank : 143)	θ value	5.44631e-05 (rank : 59)
Query Neighborhood Hits	457	Target Neighborhood Hits	1478	Shared Neighborhood Hits	243
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

NPHP1_HUMAN
NC score	0.281868 (rank : 144)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	457	Target Neighborhood Hits	288	Shared Neighborhood Hits	164
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

CING_HUMAN
NC score	0.281614 (rank : 145)	θ value	0.00228821 (rank : 114)
Query Neighborhood Hits	457	Target Neighborhood Hits	1275	Shared Neighborhood Hits	239
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

MYH3_HUMAN
NC score	0.281601 (rank : 146)	θ value	0.00665767 (rank : 149)
Query Neighborhood Hits	457	Target Neighborhood Hits	1660	Shared Neighborhood Hits	258
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

GOGA4_MOUSE
NC score	0.281373 (rank : 147)	θ value	0.813845 (rank : 309)
Query Neighborhood Hits	457	Target Neighborhood Hits	1939	Shared Neighborhood Hits	268
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

VAV3_HUMAN
NC score	0.281193 (rank : 148)	θ value	0.163984 (rank : 253)
Query Neighborhood Hits	457	Target Neighborhood Hits	398	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

AKAP9_HUMAN
NC score	0.280905 (rank : 149)	θ value	0.00509761 (rank : 136)
Query Neighborhood Hits	457	Target Neighborhood Hits	1710	Shared Neighborhood Hits	255
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CE152_HUMAN
NC score	0.280874 (rank : 150)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	457	Target Neighborhood Hits	976	Shared Neighborhood Hits	214
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

HMMR_MOUSE
NC score	0.280862 (rank : 151)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	457	Target Neighborhood Hits	1178	Shared Neighborhood Hits	234
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MYH6_HUMAN
NC score	0.279855 (rank : 152)	θ value	0.0113563 (rank : 165)
Query Neighborhood Hits	457	Target Neighborhood Hits	1426	Shared Neighborhood Hits	237
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
NC score	0.279797 (rank : 153)	θ value	0.0193708 (rank : 174)
Query Neighborhood Hits	457	Target Neighborhood Hits	1501	Shared Neighborhood Hits	246
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

TRIPB_HUMAN
NC score	0.279779 (rank : 154)	θ value	θ > 10 (rank : 1502)
Query Neighborhood Hits	457	Target Neighborhood Hits	1587	Shared Neighborhood Hits	259
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

DESP_HUMAN
NC score	0.279531 (rank : 155)	θ value	0.62314 (rank : 297)
Query Neighborhood Hits	457	Target Neighborhood Hits	1470	Shared Neighborhood Hits	255
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

MYH11_HUMAN
NC score	0.279514 (rank : 156)	θ value	0.0148317 (rank : 170)
Query Neighborhood Hits	457	Target Neighborhood Hits	1806	Shared Neighborhood Hits	275
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CCD39_HUMAN
NC score	0.279500 (rank : 157)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	457	Target Neighborhood Hits	868	Shared Neighborhood Hits	203
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

HMMR_HUMAN
NC score	0.279480 (rank : 158)	θ value	0.125558 (rank : 236)
Query Neighborhood Hits	457	Target Neighborhood Hits	1082	Shared Neighborhood Hits	216
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

STS1_MOUSE
NC score	0.279388 (rank : 159)	θ value	4.92598e-06 (rank : 34)
Query Neighborhood Hits	457	Target Neighborhood Hits	104	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

EFS_HUMAN
NC score	0.279232 (rank : 160)	θ value	0.163984 (rank : 245)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	132
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

VAV3_MOUSE
NC score	0.279222 (rank : 161)	θ value	0.163984 (rank : 254)
Query Neighborhood Hits	457	Target Neighborhood Hits	404	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

MYH7_HUMAN
NC score	0.278892 (rank : 162)	θ value	0.0252991 (rank : 179)
Query Neighborhood Hits	457	Target Neighborhood Hits	1559	Shared Neighborhood Hits	245
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RABE1_HUMAN
NC score	0.278832 (rank : 163)	θ value	0.813845 (rank : 318)
Query Neighborhood Hits	457	Target Neighborhood Hits	1104	Shared Neighborhood Hits	225
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CEP63_HUMAN
NC score	0.278831 (rank : 164)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	457	Target Neighborhood Hits	1005	Shared Neighborhood Hits	217
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

LUZP1_MOUSE
NC score	0.278757 (rank : 165)	θ value	0.0563607 (rank : 202)
Query Neighborhood Hits	457	Target Neighborhood Hits	940	Shared Neighborhood Hits	213
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MY18A_HUMAN
NC score	0.278495 (rank : 166)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	457	Target Neighborhood Hits	1929	Shared Neighborhood Hits	271
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PLCG1_HUMAN
NC score	0.277971 (rank : 167)	θ value	0.0330416 (rank : 185)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	141
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

GOGA5_HUMAN
NC score	0.277914 (rank : 168)	θ value	0.0431538 (rank : 194)
Query Neighborhood Hits	457	Target Neighborhood Hits	1168	Shared Neighborhood Hits	226
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

STS1_HUMAN
NC score	0.277809 (rank : 169)	θ value	1.09739e-05 (rank : 41)
Query Neighborhood Hits	457	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

CYTSA_MOUSE
NC score	0.277599 (rank : 170)	θ value	2.44474e-05 (rank : 47)
Query Neighborhood Hits	457	Target Neighborhood Hits	1104	Shared Neighborhood Hits	227
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

NUMA1_HUMAN
NC score	0.277506 (rank : 171)	θ value	0.0193708 (rank : 176)
Query Neighborhood Hits	457	Target Neighborhood Hits	1523	Shared Neighborhood Hits	244
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RABE1_MOUSE
NC score	0.277490 (rank : 172)	θ value	0.365318 (rank : 281)
Query Neighborhood Hits	457	Target Neighborhood Hits	1105	Shared Neighborhood Hits	229
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

MYH11_MOUSE
NC score	0.277364 (rank : 173)	θ value	0.21417 (rank : 256)
Query Neighborhood Hits	457	Target Neighborhood Hits	1777	Shared Neighborhood Hits	272
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH4_HUMAN
NC score	0.277284 (rank : 174)	θ value	0.00102713 (rank : 103)
Query Neighborhood Hits	457	Target Neighborhood Hits	1377	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

KMHN1_HUMAN
NC score	0.277197 (rank : 175)	θ value	0.0961366 (rank : 221)
Query Neighborhood Hits	457	Target Neighborhood Hits	950	Shared Neighborhood Hits	215
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

RIMB1_HUMAN
NC score	0.276906 (rank : 176)	θ value	θ > 10 (rank : 1268)
Query Neighborhood Hits	457	Target Neighborhood Hits	1479	Shared Neighborhood Hits	315
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

LUZP1_HUMAN
NC score	0.276686 (rank : 177)	θ value	6.43352e-06 (rank : 36)
Query Neighborhood Hits	457	Target Neighborhood Hits	739	Shared Neighborhood Hits	181
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

GOGA5_MOUSE
NC score	0.276452 (rank : 178)	θ value	0.00175202 (rank : 111)
Query Neighborhood Hits	457	Target Neighborhood Hits	1434	Shared Neighborhood Hits	240
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CYTSA_HUMAN
NC score	0.276191 (rank : 179)	θ value	9.29e-05 (rank : 68)
Query Neighborhood Hits	457	Target Neighborhood Hits	1138	Shared Neighborhood Hits	229
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

K0555_HUMAN
NC score	0.276128 (rank : 180)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	457	Target Neighborhood Hits	880	Shared Neighborhood Hits	222
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

BPAEA_MOUSE
NC score	0.275879 (rank : 181)	θ value	0.0148317 (rank : 168)
Query Neighborhood Hits	457	Target Neighborhood Hits	1480	Shared Neighborhood Hits	251
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TAXB1_MOUSE
NC score	0.275783 (rank : 182)	θ value	θ > 10 (rank : 1442)
Query Neighborhood Hits	457	Target Neighborhood Hits	886	Shared Neighborhood Hits	213
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

IFT74_HUMAN
NC score	0.275710 (rank : 183)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	457	Target Neighborhood Hits	949	Shared Neighborhood Hits	216
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SMC3_HUMAN
NC score	0.275509 (rank : 184)	θ value	0.365318 (rank : 282)
Query Neighborhood Hits	457	Target Neighborhood Hits	1186	Shared Neighborhood Hits	236
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

KMHN1_MOUSE
NC score	0.275273 (rank : 185)	θ value	5.27518 (rank : 406)
Query Neighborhood Hits	457	Target Neighborhood Hits	949	Shared Neighborhood Hits	225
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

CF060_HUMAN
NC score	0.275072 (rank : 186)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	457	Target Neighborhood Hits	1270	Shared Neighborhood Hits	235
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

SMC3_MOUSE
NC score	0.274730 (rank : 187)	θ value	0.62314 (rank : 304)
Query Neighborhood Hits	457	Target Neighborhood Hits	1187	Shared Neighborhood Hits	236
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SPTA1_MOUSE
NC score	0.274680 (rank : 188)	θ value	3.0926 (rank : 385)
Query Neighborhood Hits	457	Target Neighborhood Hits	675	Shared Neighborhood Hits	275
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MYH9_MOUSE
NC score	0.274592 (rank : 189)	θ value	0.0148317 (rank : 171)
Query Neighborhood Hits	457	Target Neighborhood Hits	1829	Shared Neighborhood Hits	266
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH10_HUMAN
NC score	0.273964 (rank : 190)	θ value	2.44474e-05 (rank : 48)
Query Neighborhood Hits	457	Target Neighborhood Hits	1620	Shared Neighborhood Hits	252
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CCD41_MOUSE
NC score	0.273889 (rank : 191)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	457	Target Neighborhood Hits	1399	Shared Neighborhood Hits	250
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

REST_HUMAN
NC score	0.273777 (rank : 192)	θ value	0.00665767 (rank : 152)
Query Neighborhood Hits	457	Target Neighborhood Hits	1605	Shared Neighborhood Hits	255
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
NC score	0.273520 (rank : 193)	θ value	0.0431538 (rank : 199)
Query Neighborhood Hits	457	Target Neighborhood Hits	1506	Shared Neighborhood Hits	251
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CENPE_HUMAN
NC score	0.272318 (rank : 194)	θ value	4.92598e-06 (rank : 32)
Query Neighborhood Hits	457	Target Neighborhood Hits	2060	Shared Neighborhood Hits	280
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MYH10_MOUSE
NC score	0.271874 (rank : 195)	θ value	0.0148317 (rank : 169)
Query Neighborhood Hits	457	Target Neighborhood Hits	1612	Shared Neighborhood Hits	250
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CCD62_HUMAN
NC score	0.271749 (rank : 196)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	457	Target Neighborhood Hits	631	Shared Neighborhood Hits	185
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

MYH9_HUMAN
NC score	0.271527 (rank : 197)	θ value	0.813845 (rank : 317)
Query Neighborhood Hits	457	Target Neighborhood Hits	1762	Shared Neighborhood Hits	265
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CN145_HUMAN
NC score	0.271063 (rank : 198)	θ value	6.88961 (rank : 422)
Query Neighborhood Hits	457	Target Neighborhood Hits	1196	Shared Neighborhood Hits	242
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CJ118_MOUSE
NC score	0.271054 (rank : 199)	θ value	0.365318 (rank : 274)
Query Neighborhood Hits	457	Target Neighborhood Hits	1132	Shared Neighborhood Hits	227
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CING_MOUSE
NC score	0.270689 (rank : 200)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	457	Target Neighborhood Hits	1432	Shared Neighborhood Hits	249
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

SMC4_HUMAN
NC score	0.269705 (rank : 201)	θ value	0.0736092 (rank : 215)
Query Neighborhood Hits	457	Target Neighborhood Hits	937	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

IFT81_MOUSE
NC score	0.268444 (rank : 202)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	216
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

OFD1_HUMAN
NC score	0.268334 (rank : 203)	θ value	0.0431538 (rank : 198)
Query Neighborhood Hits	457	Target Neighborhood Hits	753	Shared Neighborhood Hits	197
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

TMF1_HUMAN
NC score	0.268312 (rank : 204)	θ value	0.125558 (rank : 240)
Query Neighborhood Hits	457	Target Neighborhood Hits	987	Shared Neighborhood Hits	209
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

GOGA3_MOUSE
NC score	0.267996 (rank : 205)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	457	Target Neighborhood Hits	1437	Shared Neighborhood Hits	237
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CK5P2_MOUSE
NC score	0.267975 (rank : 206)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	457	Target Neighborhood Hits	1151	Shared Neighborhood Hits	232
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

MD1L1_MOUSE
NC score	0.267441 (rank : 207)	θ value	0.813845 (rank : 316)
Query Neighborhood Hits	457	Target Neighborhood Hits	1001	Shared Neighborhood Hits	207
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

TPR_HUMAN
NC score	0.266695 (rank : 208)	θ value	θ > 10 (rank : 1488)
Query Neighborhood Hits	457	Target Neighborhood Hits	1921	Shared Neighborhood Hits	258
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MY18B_HUMAN
NC score	0.265827 (rank : 209)	θ value	0.00509761 (rank : 144)
Query Neighborhood Hits	457	Target Neighborhood Hits	1299	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MACOI_HUMAN
NC score	0.265706 (rank : 210)	θ value	0.62314 (rank : 302)
Query Neighborhood Hits	457	Target Neighborhood Hits	650	Shared Neighborhood Hits	187
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

CCD41_HUMAN
NC score	0.265447 (rank : 211)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	457	Target Neighborhood Hits	1139	Shared Neighborhood Hits	229
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD11_HUMAN
NC score	0.264740 (rank : 212)	θ value	0.0736092 (rank : 207)
Query Neighborhood Hits	457	Target Neighborhood Hits	822	Shared Neighborhood Hits	207
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

BCAR1_MOUSE
NC score	0.264514 (rank : 213)	θ value	0.0961366 (rank : 218)
Query Neighborhood Hits	457	Target Neighborhood Hits	438	Shared Neighborhood Hits	147
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CR034_MOUSE
NC score	0.264126 (rank : 214)	θ value	6.88961 (rank : 423)
Query Neighborhood Hits	457	Target Neighborhood Hits	643	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

OPTN_MOUSE
NC score	0.264070 (rank : 215)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	457	Target Neighborhood Hits	1120	Shared Neighborhood Hits	234
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RUSC1_HUMAN
NC score	0.263180 (rank : 216)	θ value	0.0193708 (rank : 177)
Query Neighborhood Hits	457	Target Neighborhood Hits	226	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

CK5P2_HUMAN
NC score	0.263046 (rank : 217)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	457	Target Neighborhood Hits	1433	Shared Neighborhood Hits	257
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CP250_HUMAN
NC score	0.263044 (rank : 218)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	457	Target Neighborhood Hits	1805	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GOGA3_HUMAN
NC score	0.262904 (rank : 219)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	457	Target Neighborhood Hits	1317	Shared Neighborhood Hits	230
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GAS8_HUMAN
NC score	0.262878 (rank : 220)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	457	Target Neighborhood Hits	819	Shared Neighborhood Hits	211
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

SDCG8_HUMAN
NC score	0.262681 (rank : 221)	θ value	θ > 10 (rank : 1300)
Query Neighborhood Hits	457	Target Neighborhood Hits	1002	Shared Neighborhood Hits	219
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

BCAR1_HUMAN
NC score	0.261358 (rank : 222)	θ value	0.0961366 (rank : 217)
Query Neighborhood Hits	457	Target Neighborhood Hits	554	Shared Neighborhood Hits	149
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SAS6_MOUSE
NC score	0.260758 (rank : 223)	θ value	θ > 10 (rank : 1294)
Query Neighborhood Hits	457	Target Neighborhood Hits	931	Shared Neighborhood Hits	217
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

LRRF2_HUMAN
NC score	0.260652 (rank : 224)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	457	Target Neighborhood Hits	791	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

CYLN2_HUMAN
NC score	0.260631 (rank : 225)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	457	Target Neighborhood Hits	1004	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

ASPP1_HUMAN
NC score	0.260418 (rank : 226)	θ value	0.47712 (rank : 285)
Query Neighborhood Hits	457	Target Neighborhood Hits	956	Shared Neighborhood Hits	275
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TRHY_HUMAN
NC score	0.259939 (rank : 227)	θ value	0.00035302 (rank : 86)
Query Neighborhood Hits	457	Target Neighborhood Hits	1385	Shared Neighborhood Hits	225
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CP250_MOUSE
NC score	0.259688 (rank : 228)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	457	Target Neighborhood Hits	1583	Shared Neighborhood Hits	244
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

IFT74_MOUSE
NC score	0.259587 (rank : 229)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	457	Target Neighborhood Hits	939	Shared Neighborhood Hits	211
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

NIN_HUMAN
NC score	0.259577 (rank : 230)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	457	Target Neighborhood Hits	1416	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NUF2_HUMAN
NC score	0.259451 (rank : 231)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	457	Target Neighborhood Hits	661	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

CCD13_HUMAN
NC score	0.259096 (rank : 232)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	457	Target Neighborhood Hits	721	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

MACOI_MOUSE
NC score	0.258871 (rank : 233)	θ value	1.06291 (rank : 324)
Query Neighborhood Hits	457	Target Neighborhood Hits	620	Shared Neighborhood Hits	180
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

ASPP1_MOUSE
NC score	0.258696 (rank : 234)	θ value	0.0961366 (rank : 216)
Query Neighborhood Hits	457	Target Neighborhood Hits	1244	Shared Neighborhood Hits	280
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GRAP1_MOUSE
NC score	0.258663 (rank : 235)	θ value	0.365318 (rank : 277)
Query Neighborhood Hits	457	Target Neighborhood Hits	1234	Shared Neighborhood Hits	238
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SMC4_MOUSE
NC score	0.258610 (rank : 236)	θ value	1.38821 (rank : 338)
Query Neighborhood Hits	457	Target Neighborhood Hits	830	Shared Neighborhood Hits	197
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

NIN_MOUSE
NC score	0.258346 (rank : 237)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	457	Target Neighborhood Hits	1376	Shared Neighborhood Hits	236
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CYLN2_MOUSE
NC score	0.258229 (rank : 238)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	457	Target Neighborhood Hits	1002	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

SAS6_HUMAN
NC score	0.257421 (rank : 239)	θ value	0.47712 (rank : 292)
Query Neighborhood Hits	457	Target Neighborhood Hits	791	Shared Neighborhood Hits	202
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

IFT81_HUMAN
NC score	0.257195 (rank : 240)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	204
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

HOOK3_HUMAN
NC score	0.257188 (rank : 241)	θ value	0.365318 (rank : 278)
Query Neighborhood Hits	457	Target Neighborhood Hits	1070	Shared Neighborhood Hits	234
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CROCC_MOUSE
NC score	0.257182 (rank : 242)	θ value	6.88961 (rank : 424)
Query Neighborhood Hits	457	Target Neighborhood Hits	1460	Shared Neighborhood Hits	240
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CJ118_HUMAN
NC score	0.256592 (rank : 243)	θ value	4.03905 (rank : 392)
Query Neighborhood Hits	457	Target Neighborhood Hits	937	Shared Neighborhood Hits	203
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

LRRF2_MOUSE
NC score	0.256523 (rank : 244)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	457	Target Neighborhood Hits	556	Shared Neighborhood Hits	173
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

GOGA1_HUMAN
NC score	0.255771 (rank : 245)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	457	Target Neighborhood Hits	1222	Shared Neighborhood Hits	228
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MYH14_MOUSE
NC score	0.255745 (rank : 246)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	457	Target Neighborhood Hits	1225	Shared Neighborhood Hits	224
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PEPL_HUMAN
NC score	0.255518 (rank : 247)	θ value	0.62314 (rank : 303)
Query Neighborhood Hits	457	Target Neighborhood Hits	1141	Shared Neighborhood Hits	225
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

HOOK3_MOUSE
NC score	0.255323 (rank : 248)	θ value	2.36792 (rank : 365)
Query Neighborhood Hits	457	Target Neighborhood Hits	1007	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MD1L1_HUMAN
NC score	0.255100 (rank : 249)	θ value	5.27518 (rank : 410)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	205
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

BRE1A_HUMAN
NC score	0.255031 (rank : 250)	θ value	0.365318 (rank : 271)
Query Neighborhood Hits	457	Target Neighborhood Hits	1071	Shared Neighborhood Hits	225
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

UACA_HUMAN
NC score	0.254683 (rank : 251)	θ value	0.00665767 (rank : 154)
Query Neighborhood Hits	457	Target Neighborhood Hits	1622	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GOGA1_MOUSE
NC score	0.254570 (rank : 252)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	457	Target Neighborhood Hits	994	Shared Neighborhood Hits	213
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CASP_MOUSE
NC score	0.253856 (rank : 253)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	457	Target Neighborhood Hits	1152	Shared Neighborhood Hits	237
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

BICD1_HUMAN
NC score	0.253611 (rank : 254)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	457	Target Neighborhood Hits	844	Shared Neighborhood Hits	207
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

ANR26_HUMAN
NC score	0.253480 (rank : 255)	θ value	0.00509761 (rank : 137)
Query Neighborhood Hits	457	Target Neighborhood Hits	1614	Shared Neighborhood Hits	251
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

UACA_MOUSE
NC score	0.253458 (rank : 256)	θ value	0.813845 (rank : 320)
Query Neighborhood Hits	457	Target Neighborhood Hits	1620	Shared Neighborhood Hits	246
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

MYO5C_HUMAN
NC score	0.252839 (rank : 257)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	457	Target Neighborhood Hits	1206	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CASP_HUMAN
NC score	0.252811 (rank : 258)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	457	Target Neighborhood Hits	1131	Shared Neighborhood Hits	235
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

GOGA2_MOUSE
NC score	0.252445 (rank : 259)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	203
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

ASPP2_HUMAN
NC score	0.252325 (rank : 260)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	457	Target Neighborhood Hits	1156	Shared Neighborhood Hits	274
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

GRAP1_HUMAN
NC score	0.252300 (rank : 261)	θ value	6.88961 (rank : 427)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	213
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

BRE1A_MOUSE
NC score	0.252210 (rank : 262)	θ value	1.38821 (rank : 329)
Query Neighborhood Hits	457	Target Neighborhood Hits	1025	Shared Neighborhood Hits	224
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

SHLB1_MOUSE
NC score	0.252086 (rank : 263)	θ value	0.000461057 (rank : 90)
Query Neighborhood Hits	457	Target Neighborhood Hits	101	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

RRBP1_MOUSE
NC score	0.251981 (rank : 264)	θ value	0.163984 (rank : 252)
Query Neighborhood Hits	457	Target Neighborhood Hits	1650	Shared Neighborhood Hits	246
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

PCNT_HUMAN
NC score	0.251955 (rank : 265)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	457	Target Neighborhood Hits	1551	Shared Neighborhood Hits	247
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CN145_MOUSE
NC score	0.251850 (rank : 266)	θ value	5.27518 (rank : 402)
Query Neighborhood Hits	457	Target Neighborhood Hits	916	Shared Neighborhood Hits	203
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

RUSC1_MOUSE
NC score	0.251569 (rank : 267)	θ value	0.0736092 (rank : 213)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

RBCC1_MOUSE
NC score	0.251403 (rank : 268)	θ value	θ > 10 (rank : 1254)
Query Neighborhood Hits	457	Target Neighborhood Hits	1048	Shared Neighborhood Hits	222
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CROCC_HUMAN
NC score	0.251280 (rank : 269)	θ value	0.279714 (rank : 259)
Query Neighborhood Hits	457	Target Neighborhood Hits	1409	Shared Neighborhood Hits	231
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT2NL_HUMAN
NC score	0.250710 (rank : 270)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	457	Target Neighborhood Hits	1059	Shared Neighborhood Hits	229
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PEPL_MOUSE
NC score	0.250513 (rank : 271)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	457	Target Neighborhood Hits	1105	Shared Neighborhood Hits	233
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

TEX9_HUMAN
NC score	0.250433 (rank : 272)	θ value	1.38821 (rank : 340)
Query Neighborhood Hits	457	Target Neighborhood Hits	541	Shared Neighborhood Hits	171
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

CARD9_HUMAN
NC score	0.250085 (rank : 273)	θ value	1.81305 (rank : 341)
Query Neighborhood Hits	457	Target Neighborhood Hits	602	Shared Neighborhood Hits	185
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

GAS8_MOUSE
NC score	0.248708 (rank : 274)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	457	Target Neighborhood Hits	622	Shared Neighborhood Hits	185
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

BICD1_MOUSE
NC score	0.248610 (rank : 275)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	457	Target Neighborhood Hits	837	Shared Neighborhood Hits	200
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CF152_HUMAN
NC score	0.247519 (rank : 276)	θ value	5.27518 (rank : 401)
Query Neighborhood Hits	457	Target Neighborhood Hits	704	Shared Neighborhood Hits	210
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

C102B_HUMAN
NC score	0.247267 (rank : 277)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	457	Target Neighborhood Hits	542	Shared Neighborhood Hits	159
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

MYH14_HUMAN
NC score	0.246680 (rank : 278)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	457	Target Neighborhood Hits	995	Shared Neighborhood Hits	201
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RUFY2_HUMAN
NC score	0.246401 (rank : 279)	θ value	0.0736092 (rank : 212)
Query Neighborhood Hits	457	Target Neighborhood Hits	1208	Shared Neighborhood Hits	224
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CCD11_MOUSE
NC score	0.246196 (rank : 280)	θ value	0.125558 (rank : 232)
Query Neighborhood Hits	457	Target Neighborhood Hits	498	Shared Neighborhood Hits	156
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCHCR_MOUSE
NC score	0.245948 (rank : 281)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	457	Target Neighborhood Hits	932	Shared Neighborhood Hits	212
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CCD19_HUMAN
NC score	0.245914 (rank : 282)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	457	Target Neighborhood Hits	639	Shared Neighborhood Hits	179
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

RRBP1_HUMAN
NC score	0.245579 (rank : 283)	θ value	θ > 10 (rank : 1278)
Query Neighborhood Hits	457	Target Neighborhood Hits	1306	Shared Neighborhood Hits	223
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

OPTN_HUMAN
NC score	0.245174 (rank : 284)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	457	Target Neighborhood Hits	827	Shared Neighborhood Hits	208
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

EVPL_HUMAN
NC score	0.244858 (rank : 285)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	457	Target Neighborhood Hits	895	Shared Neighborhood Hits	208
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
NC score	0.244505 (rank : 286)	θ value	1.06291 (rank : 322)
Query Neighborhood Hits	457	Target Neighborhood Hits	952	Shared Neighborhood Hits	206
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

LRC45_MOUSE
NC score	0.243996 (rank : 287)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	210
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

TEX9_MOUSE
NC score	0.243758 (rank : 288)	θ value	θ > 10 (rank : 1460)
Query Neighborhood Hits	457	Target Neighborhood Hits	581	Shared Neighborhood Hits	182
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

CCD21_HUMAN
NC score	0.243598 (rank : 289)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	457	Target Neighborhood Hits	1228	Shared Neighborhood Hits	231
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SHLB1_HUMAN
NC score	0.243401 (rank : 290)	θ value	0.00134147 (rank : 108)
Query Neighborhood Hits	457	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

KNTC2_MOUSE
NC score	0.243392 (rank : 291)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	457	Target Neighborhood Hits	692	Shared Neighborhood Hits	175
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

RBCC1_HUMAN
NC score	0.243170 (rank : 292)	θ value	θ > 10 (rank : 1253)
Query Neighborhood Hits	457	Target Neighborhood Hits	1023	Shared Neighborhood Hits	213
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CALD1_HUMAN
NC score	0.243045 (rank : 293)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	196
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

SDCG8_MOUSE
NC score	0.242104 (rank : 294)	θ value	θ > 10 (rank : 1301)
Query Neighborhood Hits	457	Target Neighborhood Hits	886	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

BRE1B_HUMAN
NC score	0.241724 (rank : 295)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	457	Target Neighborhood Hits	1040	Shared Neighborhood Hits	201
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MIPO1_HUMAN
NC score	0.241124 (rank : 296)	θ value	1.81305 (rank : 347)
Query Neighborhood Hits	457	Target Neighborhood Hits	486	Shared Neighborhood Hits	162
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MPP9_HUMAN
NC score	0.241001 (rank : 297)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	457	Target Neighborhood Hits	529	Shared Neighborhood Hits	164
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

CCD21_MOUSE
NC score	0.240922 (rank : 298)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MYO5A_HUMAN
NC score	0.240152 (rank : 299)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	457	Target Neighborhood Hits	1092	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

GOGA6_HUMAN
NC score	0.239650 (rank : 300)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	457	Target Neighborhood Hits	1007	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

MYO5A_MOUSE
NC score	0.239415 (rank : 301)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	457	Target Neighborhood Hits	1117	Shared Neighborhood Hits	236
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

FYCO1_MOUSE
NC score	0.239391 (rank : 302)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	457	Target Neighborhood Hits	1059	Shared Neighborhood Hits	200
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

INCE_MOUSE
NC score	0.239298 (rank : 303)	θ value	0.813845 (rank : 313)
Query Neighborhood Hits	457	Target Neighborhood Hits	903	Shared Neighborhood Hits	200
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

SYNE1_HUMAN
NC score	0.239156 (rank : 304)	θ value	1.81305 (rank : 357)
Query Neighborhood Hits	457	Target Neighborhood Hits	1484	Shared Neighborhood Hits	235
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

KNTC2_HUMAN
NC score	0.238848 (rank : 305)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	457	Target Neighborhood Hits	673	Shared Neighborhood Hits	182
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

CKAP4_MOUSE
NC score	0.238846 (rank : 306)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	457	Target Neighborhood Hits	596	Shared Neighborhood Hits	165
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CASL_MOUSE
NC score	0.238045 (rank : 307)	θ value	3.0926 (rank : 378)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	136
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

POF1B_MOUSE
NC score	0.237727 (rank : 308)	θ value	θ > 10 (rank : 1232)
Query Neighborhood Hits	457	Target Neighborhood Hits	530	Shared Neighborhood Hits	162
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

AZI1_HUMAN
NC score	0.237290 (rank : 309)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	457	Target Neighborhood Hits	1000	Shared Neighborhood Hits	209
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CR034_HUMAN
NC score	0.237160 (rank : 310)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	457	Target Neighborhood Hits	538	Shared Neighborhood Hits	176
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

HOOK1_HUMAN
NC score	0.236794 (rank : 311)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	457	Target Neighborhood Hits	942	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

AZI1_MOUSE
NC score	0.236669 (rank : 312)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	457	Target Neighborhood Hits	990	Shared Neighborhood Hits	218
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

HOOK1_MOUSE
NC score	0.236260 (rank : 313)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	457	Target Neighborhood Hits	910	Shared Neighborhood Hits	202
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

NUF2_MOUSE
NC score	0.236026 (rank : 314)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	457	Target Neighborhood Hits	585	Shared Neighborhood Hits	180
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

ANR26_MOUSE
NC score	0.235668 (rank : 315)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	457	Target Neighborhood Hits	1554	Shared Neighborhood Hits	239
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TUFT1_HUMAN
NC score	0.235643 (rank : 316)	θ value	θ > 10 (rank : 1509)
Query Neighborhood Hits	457	Target Neighborhood Hits	686	Shared Neighborhood Hits	190
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CEP55_MOUSE
NC score	0.235389 (rank : 317)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	457	Target Neighborhood Hits	693	Shared Neighborhood Hits	187
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

PCNT_MOUSE
NC score	0.235300 (rank : 318)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	457	Target Neighborhood Hits	1207	Shared Neighborhood Hits	214
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

BICD2_MOUSE
NC score	0.235266 (rank : 319)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	457	Target Neighborhood Hits	864	Shared Neighborhood Hits	202
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

POF1B_HUMAN
NC score	0.234255 (rank : 320)	θ value	θ > 10 (rank : 1231)
Query Neighborhood Hits	457	Target Neighborhood Hits	494	Shared Neighborhood Hits	165
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

TUFT1_MOUSE
NC score	0.234179 (rank : 321)	θ value	θ > 10 (rank : 1510)
Query Neighborhood Hits	457	Target Neighborhood Hits	732	Shared Neighborhood Hits	193
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CASL_HUMAN
NC score	0.234025 (rank : 322)	θ value	3.0926 (rank : 377)
Query Neighborhood Hits	457	Target Neighborhood Hits	259	Shared Neighborhood Hits	134
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

EP15R_HUMAN
NC score	0.233985 (rank : 323)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	457	Target Neighborhood Hits	1083	Shared Neighborhood Hits	215
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

LRC45_HUMAN
NC score	0.233969 (rank : 324)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	457	Target Neighborhood Hits	933	Shared Neighborhood Hits	204
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

P85B_HUMAN
NC score	0.233883 (rank : 325)	θ value	0.365318 (rank : 280)
Query Neighborhood Hits	457	Target Neighborhood Hits	543	Shared Neighborhood Hits	200
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CT2NL_MOUSE
NC score	0.233858 (rank : 326)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	457	Target Neighborhood Hits	902	Shared Neighborhood Hits	214
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

TPM1_MOUSE
NC score	0.233509 (rank : 327)	θ value	2.36792 (rank : 374)
Query Neighborhood Hits	457	Target Neighborhood Hits	729	Shared Neighborhood Hits	197
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

IF3A_MOUSE
NC score	0.233471 (rank : 328)	θ value	1.81305 (rank : 345)
Query Neighborhood Hits	457	Target Neighborhood Hits	871	Shared Neighborhood Hits	199
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

CCDC6_HUMAN
NC score	0.233318 (rank : 329)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	186
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

BICD2_HUMAN
NC score	0.233278 (rank : 330)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	202
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

ARHG4_HUMAN
NC score	0.233195 (rank : 331)	θ value	0.813845 (rank : 306)
Query Neighborhood Hits	457	Target Neighborhood Hits	242	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

GCC1_HUMAN
NC score	0.232604 (rank : 332)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	457	Target Neighborhood Hits	887	Shared Neighborhood Hits	196
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

LIPA1_HUMAN
NC score	0.232512 (rank : 333)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	457	Target Neighborhood Hits	1294	Shared Neighborhood Hits	240
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

FYCO1_HUMAN
NC score	0.232350 (rank : 334)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	457	Target Neighborhood Hits	1149	Shared Neighborhood Hits	206
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TRAIP_MOUSE
NC score	0.232319 (rank : 335)	θ value	θ > 10 (rank : 1496)
Query Neighborhood Hits	457	Target Neighborhood Hits	745	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

INCE_HUMAN
NC score	0.232275 (rank : 336)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	457	Target Neighborhood Hits	978	Shared Neighborhood Hits	201
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

TRAIP_HUMAN
NC score	0.232139 (rank : 337)	θ value	θ > 10 (rank : 1495)
Query Neighborhood Hits	457	Target Neighborhood Hits	780	Shared Neighborhood Hits	189
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

LIPA2_MOUSE
NC score	0.231950 (rank : 338)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	457	Target Neighborhood Hits	1282	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TSC1_HUMAN
NC score	0.231766 (rank : 339)	θ value	θ > 10 (rank : 1505)
Query Neighborhood Hits	457	Target Neighborhood Hits	765	Shared Neighborhood Hits	171
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

SYNE2_HUMAN
NC score	0.230954 (rank : 340)	θ value	1.81305 (rank : 358)
Query Neighborhood Hits	457	Target Neighborhood Hits	1323	Shared Neighborhood Hits	219
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

LIPB1_MOUSE
NC score	0.230866 (rank : 341)	θ value	0.0193708 (rank : 173)
Query Neighborhood Hits	457	Target Neighborhood Hits	727	Shared Neighborhood Hits	184
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

IF3A_HUMAN
NC score	0.230850 (rank : 342)	θ value	1.81305 (rank : 344)
Query Neighborhood Hits	457	Target Neighborhood Hits	875	Shared Neighborhood Hits	199
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

CCD91_HUMAN
NC score	0.230827 (rank : 343)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	457	Target Neighborhood Hits	868	Shared Neighborhood Hits	213
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CKAP4_HUMAN
NC score	0.230810 (rank : 344)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	457	Target Neighborhood Hits	592	Shared Neighborhood Hits	166
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

TPM1_HUMAN
NC score	0.230802 (rank : 345)	θ value	5.27518 (rank : 417)
Query Neighborhood Hits	457	Target Neighborhood Hits	716	Shared Neighborhood Hits	193
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

DMD_MOUSE
NC score	0.230772 (rank : 346)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	457	Target Neighborhood Hits	1111	Shared Neighborhood Hits	223
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

BPAEA_HUMAN
NC score	0.230589 (rank : 347)	θ value	0.279714 (rank : 257)
Query Neighborhood Hits	457	Target Neighborhood Hits	1369	Shared Neighborhood Hits	224
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RHG26_HUMAN
NC score	0.230504 (rank : 348)	θ value	2.44474e-05 (rank : 49)
Query Neighborhood Hits	457	Target Neighborhood Hits	281	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

GCC1_MOUSE
NC score	0.230250 (rank : 349)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	457	Target Neighborhood Hits	777	Shared Neighborhood Hits	189
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGA2_HUMAN
NC score	0.230009 (rank : 350)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	186
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

CENPH_HUMAN
NC score	0.229855 (rank : 351)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	144
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

BRE1B_MOUSE
NC score	0.229789 (rank : 352)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	457	Target Neighborhood Hits	970	Shared Neighborhood Hits	192
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MACF4_HUMAN
NC score	0.229777 (rank : 353)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	457	Target Neighborhood Hits	1321	Shared Neighborhood Hits	217
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

P85B_MOUSE
NC score	0.229629 (rank : 354)	θ value	0.47712 (rank : 290)
Query Neighborhood Hits	457	Target Neighborhood Hits	519	Shared Neighborhood Hits	199
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CEP55_HUMAN
NC score	0.229556 (rank : 355)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	165
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

EP15R_MOUSE
NC score	0.229466 (rank : 356)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	224
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

NDE1_HUMAN
NC score	0.228826 (rank : 357)	θ value	1.38821 (rank : 331)
Query Neighborhood Hits	457	Target Neighborhood Hits	823	Shared Neighborhood Hits	201
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

CCHCR_HUMAN
NC score	0.228515 (rank : 358)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	457	Target Neighborhood Hits	717	Shared Neighborhood Hits	180
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

TPM4_MOUSE
NC score	0.228098 (rank : 359)	θ value	θ > 10 (rank : 1487)
Query Neighborhood Hits	457	Target Neighborhood Hits	703	Shared Neighborhood Hits	197
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

CCD93_HUMAN
NC score	0.227818 (rank : 360)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	457	Target Neighborhood Hits	600	Shared Neighborhood Hits	170
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

HOME2_MOUSE
NC score	0.227743 (rank : 361)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	457	Target Neighborhood Hits	882	Shared Neighborhood Hits	222
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

TPM3_MOUSE
NC score	0.227664 (rank : 362)	θ value	0.279714 (rank : 268)
Query Neighborhood Hits	457	Target Neighborhood Hits	676	Shared Neighborhood Hits	169
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM3_HUMAN
NC score	0.227598 (rank : 363)	θ value	0.365318 (rank : 284)
Query Neighborhood Hits	457	Target Neighborhood Hits	689	Shared Neighborhood Hits	168
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

HIP1_HUMAN
NC score	0.227135 (rank : 364)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	457	Target Neighborhood Hits	1016	Shared Neighborhood Hits	219
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

RFIP4_HUMAN
NC score	0.227055 (rank : 365)	θ value	θ > 10 (rank : 1260)
Query Neighborhood Hits	457	Target Neighborhood Hits	785	Shared Neighborhood Hits	201
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CCD96_MOUSE
NC score	0.226679 (rank : 366)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	457	Target Neighborhood Hits	704	Shared Neighborhood Hits	184
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

KINH_HUMAN
NC score	0.226346 (rank : 367)	θ value	0.47712 (rank : 288)
Query Neighborhood Hits	457	Target Neighborhood Hits	1231	Shared Neighborhood Hits	239
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CUTL1_MOUSE
NC score	0.226270 (rank : 368)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	457	Target Neighborhood Hits	1620	Shared Neighborhood Hits	244
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CTGE5_MOUSE
NC score	0.226175 (rank : 369)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	457	Target Neighborhood Hits	928	Shared Neighborhood Hits	211
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

LIPA2_HUMAN
NC score	0.225886 (rank : 370)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	457	Target Neighborhood Hits	1044	Shared Neighborhood Hits	221
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CUTL1_HUMAN
NC score	0.225805 (rank : 371)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	457	Target Neighborhood Hits	1574	Shared Neighborhood Hits	236
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

PLEC1_HUMAN
NC score	0.225767 (rank : 372)	θ value	0.000270298 (rank : 79)
Query Neighborhood Hits	457	Target Neighborhood Hits	1326	Shared Neighborhood Hits	213
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

DMD_HUMAN
NC score	0.225095 (rank : 373)	θ value	0.47712 (rank : 287)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	219
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CCD91_MOUSE
NC score	0.224711 (rank : 374)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	457	Target Neighborhood Hits	699	Shared Neighborhood Hits	188
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD27_MOUSE
NC score	0.224029 (rank : 375)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	457	Target Neighborhood Hits	461	Shared Neighborhood Hits	143
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

RFIP3_HUMAN
NC score	0.223814 (rank : 376)	θ value	θ > 10 (rank : 1259)
Query Neighborhood Hits	457	Target Neighborhood Hits	1055	Shared Neighborhood Hits	200
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

ANM2_HUMAN
NC score	0.223579 (rank : 377)	θ value	0.0148317 (rank : 167)
Query Neighborhood Hits	457	Target Neighborhood Hits	175	Shared Neighborhood Hits	127
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

LIPB1_HUMAN
NC score	0.223488 (rank : 378)	θ value	0.000461057 (rank : 89)
Query Neighborhood Hits	457	Target Neighborhood Hits	640	Shared Neighborhood Hits	177
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

HIP1R_MOUSE
NC score	0.222719 (rank : 379)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	457	Target Neighborhood Hits	959	Shared Neighborhood Hits	207
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

CIP4_HUMAN
NC score	0.222629 (rank : 380)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	457	Target Neighborhood Hits	374	Shared Neighborhood Hits	159
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

MMRN1_HUMAN
NC score	0.222485 (rank : 381)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	457	Target Neighborhood Hits	636	Shared Neighborhood Hits	148
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

TPM2_HUMAN
NC score	0.222174 (rank : 382)	θ value	θ > 10 (rank : 1484)
Query Neighborhood Hits	457	Target Neighborhood Hits	677	Shared Neighborhood Hits	172
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

CCD96_HUMAN
NC score	0.222173 (rank : 383)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	457	Target Neighborhood Hits	595	Shared Neighborhood Hits	155
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CU013_HUMAN
NC score	0.222139 (rank : 384)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	457	Target Neighborhood Hits	405	Shared Neighborhood Hits	146
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

TRAK1_HUMAN
NC score	0.221641 (rank : 385)	θ value	θ > 10 (rank : 1497)
Query Neighborhood Hits	457	Target Neighborhood Hits	660	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

INVO_HUMAN
NC score	0.221336 (rank : 386)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	457	Target Neighborhood Hits	636	Shared Neighborhood Hits	149
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

RAI14_MOUSE
NC score	0.221011 (rank : 387)	θ value	0.00665767 (rank : 151)
Query Neighborhood Hits	457	Target Neighborhood Hits	1505	Shared Neighborhood Hits	238
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TPM2_MOUSE
NC score	0.220921 (rank : 388)	θ value	θ > 10 (rank : 1485)
Query Neighborhood Hits	457	Target Neighborhood Hits	676	Shared Neighborhood Hits	172
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

MYO5B_HUMAN
NC score	0.220801 (rank : 389)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	457	Target Neighborhood Hits	911	Shared Neighborhood Hits	212
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

CTGE5_HUMAN
NC score	0.220624 (rank : 390)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	457	Target Neighborhood Hits	800	Shared Neighborhood Hits	214
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

IF2P_HUMAN
NC score	0.219285 (rank : 391)	θ value	0.279714 (rank : 261)
Query Neighborhood Hits	457	Target Neighborhood Hits	889	Shared Neighborhood Hits	188
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

P85A_HUMAN
NC score	0.219127 (rank : 392)	θ value	0.00228821 (rank : 117)
Query Neighborhood Hits	457	Target Neighborhood Hits	479	Shared Neighborhood Hits	185
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

BPA1_MOUSE
NC score	0.219098 (rank : 393)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	457	Target Neighborhood Hits	1477	Shared Neighborhood Hits	229
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DYNA_HUMAN
NC score	0.219048 (rank : 394)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	457	Target Neighborhood Hits	1194	Shared Neighborhood Hits	216
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
NC score	0.218758 (rank : 395)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	457	Target Neighborhood Hits	1084	Shared Neighborhood Hits	210
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EP15_HUMAN
NC score	0.218665 (rank : 396)	θ value	0.62314 (rank : 298)
Query Neighborhood Hits	457	Target Neighborhood Hits	1021	Shared Neighborhood Hits	200
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CAR11_HUMAN
NC score	0.218427 (rank : 397)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	457	Target Neighborhood Hits	690	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

TNIP3_HUMAN
NC score	0.218075 (rank : 398)	θ value	θ > 10 (rank : 1477)
Query Neighborhood Hits	457	Target Neighborhood Hits	511	Shared Neighborhood Hits	156
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

CEP70_HUMAN
NC score	0.217925 (rank : 399)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	457	Target Neighborhood Hits	432	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

NEMO_MOUSE
NC score	0.217793 (rank : 400)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	457	Target Neighborhood Hits	658	Shared Neighborhood Hits	175
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

SPAG5_MOUSE
NC score	0.217793 (rank : 401)	θ value	θ > 10 (rank : 1361)
Query Neighborhood Hits	457	Target Neighborhood Hits	612	Shared Neighborhood Hits	159
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

RFIP4_MOUSE
NC score	0.217553 (rank : 402)	θ value	θ > 10 (rank : 1261)
Query Neighborhood Hits	457	Target Neighborhood Hits	708	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

EP15_MOUSE
NC score	0.217396 (rank : 403)	θ value	0.0431538 (rank : 193)
Query Neighborhood Hits	457	Target Neighborhood Hits	820	Shared Neighborhood Hits	178
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CRCM_HUMAN
NC score	0.217056 (rank : 404)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	457	Target Neighborhood Hits	520	Shared Neighborhood Hits	154
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

TPM4_HUMAN
NC score	0.216974 (rank : 405)	θ value	θ > 10 (rank : 1486)
Query Neighborhood Hits	457	Target Neighborhood Hits	525	Shared Neighborhood Hits	160
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

P85A_MOUSE
NC score	0.216973 (rank : 406)	θ value	0.000786445 (rank : 98)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	169
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SHLB2_MOUSE
NC score	0.216327 (rank : 407)	θ value	0.47712 (rank : 294)
Query Neighborhood Hits	457	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

DLG5_HUMAN
NC score	0.216209 (rank : 408)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	457	Target Neighborhood Hits	1088	Shared Neighborhood Hits	224
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

CLC4F_HUMAN
NC score	0.216004 (rank : 409)	θ value	0.125558 (rank : 233)
Query Neighborhood Hits	457	Target Neighborhood Hits	513	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

NAF1_MOUSE
NC score	0.215735 (rank : 410)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	457	Target Neighborhood Hits	852	Shared Neighborhood Hits	202
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NAF1_HUMAN
NC score	0.215660 (rank : 411)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	457	Target Neighborhood Hits	937	Shared Neighborhood Hits	211
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

MACF1_HUMAN
NC score	0.215360 (rank : 412)	θ value	0.47712 (rank : 289)
Query Neighborhood Hits	457	Target Neighborhood Hits	1341	Shared Neighborhood Hits	213
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PHLB2_MOUSE
NC score	0.215070 (rank : 413)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	457	Target Neighborhood Hits	1016	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CNTRB_MOUSE
NC score	0.214944 (rank : 414)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	457	Target Neighborhood Hits	1029	Shared Neighborhood Hits	207
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CDR2_MOUSE
NC score	0.214926 (rank : 415)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	457	Target Neighborhood Hits	482	Shared Neighborhood Hits	159
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

PPIP2_HUMAN
NC score	0.214272 (rank : 416)	θ value	θ > 10 (rank : 1235)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

CEP70_MOUSE
NC score	0.213996 (rank : 417)	θ value	6.88961 (rank : 421)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	161
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

PHLB2_HUMAN
NC score	0.213776 (rank : 418)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	457	Target Neighborhood Hits	964	Shared Neighborhood Hits	213
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SHLB2_HUMAN
NC score	0.213735 (rank : 419)	θ value	0.47712 (rank : 293)
Query Neighborhood Hits	457	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

NEMO_HUMAN
NC score	0.213409 (rank : 420)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	457	Target Neighborhood Hits	820	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

RABE2_MOUSE
NC score	0.213208 (rank : 421)	θ value	θ > 10 (rank : 1248)
Query Neighborhood Hits	457	Target Neighborhood Hits	598	Shared Neighborhood Hits	170
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

KINH_MOUSE
NC score	0.212963 (rank : 422)	θ value	1.06291 (rank : 323)
Query Neighborhood Hits	457	Target Neighborhood Hits	1082	Shared Neighborhood Hits	232
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CTGE6_HUMAN
NC score	0.212799 (rank : 423)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	457	Target Neighborhood Hits	650	Shared Neighborhood Hits	183
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

ZN291_HUMAN
NC score	0.212602 (rank : 424)	θ value	θ > 10 (rank : 1555)
Query Neighborhood Hits	457	Target Neighborhood Hits	647	Shared Neighborhood Hits	171
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

T3JAM_HUMAN
NC score	0.211991 (rank : 425)	θ value	θ > 10 (rank : 1421)
Query Neighborhood Hits	457	Target Neighborhood Hits	533	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

RUFY1_HUMAN
NC score	0.211793 (rank : 426)	θ value	θ > 10 (rank : 1281)
Query Neighborhood Hits	457	Target Neighborhood Hits	848	Shared Neighborhood Hits	196
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

ANM2_MOUSE
NC score	0.211644 (rank : 427)	θ value	0.0431538 (rank : 187)
Query Neighborhood Hits	457	Target Neighborhood Hits	175	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

SWP70_MOUSE
NC score	0.211246 (rank : 428)	θ value	θ > 10 (rank : 1413)
Query Neighborhood Hits	457	Target Neighborhood Hits	1097	Shared Neighborhood Hits	214
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RUFY2_MOUSE
NC score	0.211192 (rank : 429)	θ value	θ > 10 (rank : 1283)
Query Neighborhood Hits	457	Target Neighborhood Hits	820	Shared Neighborhood Hits	186
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CCD27_HUMAN
NC score	0.211089 (rank : 430)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	457	Target Neighborhood Hits	594	Shared Neighborhood Hits	161
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

ADIP_HUMAN
NC score	0.210774 (rank : 431)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	457	Target Neighborhood Hits	470	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

SPAG5_HUMAN
NC score	0.210601 (rank : 432)	θ value	θ > 10 (rank : 1360)
Query Neighborhood Hits	457	Target Neighborhood Hits	625	Shared Neighborhood Hits	176
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

RBM25_HUMAN
NC score	0.210521 (rank : 433)	θ value	0.163984 (rank : 251)
Query Neighborhood Hits	457	Target Neighborhood Hits	682	Shared Neighborhood Hits	165
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

PPIP2_MOUSE
NC score	0.209651 (rank : 434)	θ value	θ > 10 (rank : 1236)
Query Neighborhood Hits	457	Target Neighborhood Hits	308	Shared Neighborhood Hits	129
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

ZWINT_MOUSE
NC score	0.209548 (rank : 435)	θ value	θ > 10 (rank : 1564)
Query Neighborhood Hits	457	Target Neighborhood Hits	497	Shared Neighborhood Hits	161
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

MAP1A_HUMAN
NC score	0.209388 (rank : 436)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	457	Target Neighborhood Hits	1626	Shared Neighborhood Hits	231
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

AN30A_HUMAN
NC score	0.209345 (rank : 437)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	457	Target Neighborhood Hits	1119	Shared Neighborhood Hits	218
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

KIF4A_HUMAN
NC score	0.209294 (rank : 438)	θ value	0.365318 (rank : 279)
Query Neighborhood Hits	457	Target Neighborhood Hits	1159	Shared Neighborhood Hits	225
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

RUFY3_HUMAN
NC score	0.209036 (rank : 439)	θ value	θ > 10 (rank : 1284)
Query Neighborhood Hits	457	Target Neighborhood Hits	594	Shared Neighborhood Hits	183
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

VDP_HUMAN
NC score	0.208838 (rank : 440)	θ value	θ > 10 (rank : 1532)
Query Neighborhood Hits	457	Target Neighborhood Hits	645	Shared Neighborhood Hits	172
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CEP57_HUMAN
NC score	0.208760 (rank : 441)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	457	Target Neighborhood Hits	576	Shared Neighborhood Hits	173
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

SWP70_HUMAN
NC score	0.208663 (rank : 442)	θ value	θ > 10 (rank : 1412)
Query Neighborhood Hits	457	Target Neighborhood Hits	973	Shared Neighborhood Hits	205
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CF152_MOUSE
NC score	0.208250 (rank : 443)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	457	Target Neighborhood Hits	597	Shared Neighborhood Hits	179
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

XE7_HUMAN
NC score	0.208142 (rank : 444)	θ value	θ > 10 (rank : 1546)
Query Neighborhood Hits	457	Target Neighborhood Hits	738	Shared Neighborhood Hits	184
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

IASPP_HUMAN
NC score	0.207929 (rank : 445)	θ value	0.0563607 (rank : 201)
Query Neighborhood Hits	457	Target Neighborhood Hits	688	Shared Neighborhood Hits	150
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LZTS1_MOUSE
NC score	0.207659 (rank : 446)	θ value	0.813845 (rank : 315)
Query Neighborhood Hits	457	Target Neighborhood Hits	540	Shared Neighborhood Hits	157
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

HOOK2_MOUSE
NC score	0.207473 (rank : 447)	θ value	6.88961 (rank : 428)
Query Neighborhood Hits	457	Target Neighborhood Hits	736	Shared Neighborhood Hits	186
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

LZTS1_HUMAN
NC score	0.207278 (rank : 448)	θ value	5.27518 (rank : 409)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MACF1_MOUSE
NC score	0.206769 (rank : 449)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	457	Target Neighborhood Hits	1313	Shared Neighborhood Hits	207
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

P55G_HUMAN
NC score	0.206174 (rank : 450)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	457	Target Neighborhood Hits	451	Shared Neighborhood Hits	181
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

GOG8A_HUMAN
NC score	0.206124 (rank : 451)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	457	Target Neighborhood Hits	635	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

NDE1_MOUSE
NC score	0.206011 (rank : 452)	θ value	1.81305 (rank : 348)
Query Neighborhood Hits	457	Target Neighborhood Hits	602	Shared Neighborhood Hits	172
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

HIP1R_HUMAN
NC score	0.205790 (rank : 453)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	457	Target Neighborhood Hits	809	Shared Neighborhood Hits	195
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

RUFY3_MOUSE
NC score	0.204814 (rank : 454)	θ value	θ > 10 (rank : 1285)
Query Neighborhood Hits	457	Target Neighborhood Hits	579	Shared Neighborhood Hits	180
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

HOOK2_HUMAN
NC score	0.204704 (rank : 455)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	457	Target Neighborhood Hits	714	Shared Neighborhood Hits	183
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

NOXO1_MOUSE
NC score	0.204110 (rank : 456)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	457	Target Neighborhood Hits	114	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

UTRO_HUMAN
NC score	0.204053 (rank : 457)	θ value	θ > 10 (rank : 1530)
Query Neighborhood Hits	457	Target Neighborhood Hits	960	Shared Neighborhood Hits	197
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

TXLNA_MOUSE
NC score	0.203303 (rank : 458)	θ value	θ > 10 (rank : 1515)
Query Neighborhood Hits	457	Target Neighborhood Hits	846	Shared Neighborhood Hits	179
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TACC3_MOUSE
NC score	0.203047 (rank : 459)	θ value	θ > 10 (rank : 1428)
Query Neighborhood Hits	457	Target Neighborhood Hits	607	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

PLCB4_HUMAN
NC score	0.202940 (rank : 460)	θ value	1.81305 (rank : 351)
Query Neighborhood Hits	457	Target Neighborhood Hits	658	Shared Neighborhood Hits	188
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

CENPJ_HUMAN
NC score	0.202482 (rank : 461)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	457	Target Neighborhood Hits	721	Shared Neighborhood Hits	197
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

3BP5_HUMAN
NC score	0.202161 (rank : 462)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	457	Target Neighborhood Hits	375	Shared Neighborhood Hits	143
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

NEST_HUMAN
NC score	0.201994 (rank : 463)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	457	Target Neighborhood Hits	1305	Shared Neighborhood Hits	213
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

RAI14_HUMAN
NC score	0.201728 (rank : 464)	θ value	0.000602161 (rank : 93)
Query Neighborhood Hits	457	Target Neighborhood Hits	1367	Shared Neighborhood Hits	217
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RUFY1_MOUSE
NC score	0.201405 (rank : 465)	θ value	θ > 10 (rank : 1282)
Query Neighborhood Hits	457	Target Neighborhood Hits	765	Shared Neighborhood Hits	179
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

ARHG9_MOUSE
NC score	0.201280 (rank : 466)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	457	Target Neighborhood Hits	234	Shared Neighborhood Hits	141
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.201162 (rank : 467)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	144
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

TACC2_HUMAN
NC score	0.201046 (rank : 468)	θ value	θ > 10 (rank : 1425)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	202
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CCD42_HUMAN
NC score	0.199963 (rank : 469)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	457	Target Neighborhood Hits	406	Shared Neighborhood Hits	150
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

RPGR1_HUMAN
NC score	0.199660 (rank : 470)	θ value	θ > 10 (rank : 1276)
Query Neighborhood Hits	457	Target Neighborhood Hits	578	Shared Neighborhood Hits	159
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

FNBP2_HUMAN
NC score	0.199607 (rank : 471)	θ value	3.0926 (rank : 379)
Query Neighborhood Hits	457	Target Neighborhood Hits	432	Shared Neighborhood Hits	204
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TACC1_HUMAN
NC score	0.199577 (rank : 472)	θ value	θ > 10 (rank : 1423)
Query Neighborhood Hits	457	Target Neighborhood Hits	597	Shared Neighborhood Hits	175
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
NC score	0.199266 (rank : 473)	θ value	θ > 10 (rank : 1424)
Query Neighborhood Hits	457	Target Neighborhood Hits	667	Shared Neighborhood Hits	177
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

CF182_HUMAN
NC score	0.198434 (rank : 474)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	457	Target Neighborhood Hits	474	Shared Neighborhood Hits	158
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CEP57_MOUSE
NC score	0.198315 (rank : 475)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	457	Target Neighborhood Hits	580	Shared Neighborhood Hits	174
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

DDEF1_MOUSE
NC score	0.198079 (rank : 476)	θ value	0.0431538 (rank : 189)
Query Neighborhood Hits	457	Target Neighborhood Hits	592	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

KIF5C_MOUSE
NC score	0.197791 (rank : 477)	θ value	0.163984 (rank : 248)
Query Neighborhood Hits	457	Target Neighborhood Hits	1040	Shared Neighborhood Hits	228
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

TRDN_HUMAN
NC score	0.197778 (rank : 478)	θ value	1.87187e-05 (rank : 46)
Query Neighborhood Hits	457	Target Neighborhood Hits	542	Shared Neighborhood Hits	123
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

CTGE2_HUMAN
NC score	0.197255 (rank : 479)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	457	Target Neighborhood Hits	594	Shared Neighborhood Hits	170
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

P55G_MOUSE
NC score	0.196996 (rank : 480)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	457	Target Neighborhood Hits	401	Shared Neighborhood Hits	168
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

ANR18_HUMAN
NC score	0.196953 (rank : 481)	θ value	0.0736092 (rank : 205)
Query Neighborhood Hits	457	Target Neighborhood Hits	1106	Shared Neighborhood Hits	221
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CCD45_MOUSE
NC score	0.196560 (rank : 482)	θ value	6.88961 (rank : 420)
Query Neighborhood Hits	457	Target Neighborhood Hits	663	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

KIF4A_MOUSE
NC score	0.196544 (rank : 483)	θ value	3.0926 (rank : 381)
Query Neighborhood Hits	457	Target Neighborhood Hits	1033	Shared Neighborhood Hits	216
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

TXLNA_HUMAN
NC score	0.196363 (rank : 484)	θ value	θ > 10 (rank : 1514)
Query Neighborhood Hits	457	Target Neighborhood Hits	982	Shared Neighborhood Hits	188
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

RIMB2_MOUSE
NC score	0.196073 (rank : 485)	θ value	θ > 10 (rank : 1269)
Query Neighborhood Hits	457	Target Neighborhood Hits	246	Shared Neighborhood Hits	117
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ARHG5_HUMAN
NC score	0.196008 (rank : 486)	θ value	0.00665767 (rank : 147)
Query Neighborhood Hits	457	Target Neighborhood Hits	172	Shared Neighborhood Hits	96
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

REN3B_HUMAN
NC score	0.195949 (rank : 487)	θ value	0.47712 (rank : 291)
Query Neighborhood Hits	457	Target Neighborhood Hits	412	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

CT096_HUMAN
NC score	0.195885 (rank : 488)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	457	Target Neighborhood Hits	438	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CNTRB_HUMAN
NC score	0.195722 (rank : 489)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	457	Target Neighborhood Hits	690	Shared Neighborhood Hits	159
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

TEKT1_MOUSE
NC score	0.195660 (rank : 490)	θ value	θ > 10 (rank : 1453)
Query Neighborhood Hits	457	Target Neighborhood Hits	399	Shared Neighborhood Hits	146
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TRAK2_HUMAN
NC score	0.195605 (rank : 491)	θ value	θ > 10 (rank : 1498)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	157
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

CYLC1_HUMAN
NC score	0.195286 (rank : 492)	θ value	0.00665767 (rank : 148)
Query Neighborhood Hits	457	Target Neighborhood Hits	408	Shared Neighborhood Hits	96
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MYO6_HUMAN
NC score	0.195228 (rank : 493)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	457	Target Neighborhood Hits	727	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

CF182_MOUSE
NC score	0.194837 (rank : 494)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	457	Target Neighborhood Hits	551	Shared Neighborhood Hits	155
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CCD45_HUMAN
NC score	0.194775 (rank : 495)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	457	Target Neighborhood Hits	525	Shared Neighborhood Hits	167
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MYO10_HUMAN
NC score	0.194641 (rank : 496)	θ value	2.36792 (rank : 368)
Query Neighborhood Hits	457	Target Neighborhood Hits	920	Shared Neighborhood Hits	203
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

RABE2_HUMAN
NC score	0.193765 (rank : 497)	θ value	θ > 10 (rank : 1247)
Query Neighborhood Hits	457	Target Neighborhood Hits	545	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

CDR2_HUMAN
NC score	0.193276 (rank : 498)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	457	Target Neighborhood Hits	404	Shared Neighborhood Hits	147
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

RIMB2_HUMAN
NC score	0.193132 (rank : 499)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	117
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TXLNG_HUMAN
NC score	0.192691 (rank : 500)	θ value	8.99809 (rank : 457)
Query Neighborhood Hits	457	Target Neighborhood Hits	568	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

YO11_MOUSE
NC score	0.191330 (rank : 501)	θ value	θ > 10 (rank : 1550)
Query Neighborhood Hits	457	Target Neighborhood Hits	272	Shared Neighborhood Hits	114
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

3BP5_MOUSE
NC score	0.191326 (rank : 502)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	457	Target Neighborhood Hits	346	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

LIPA3_HUMAN
NC score	0.191155 (rank : 503)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	457	Target Neighborhood Hits	828	Shared Neighborhood Hits	188
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MYO6_MOUSE
NC score	0.190733 (rank : 504)	θ value	0.0961366 (rank : 225)
Query Neighborhood Hits	457	Target Neighborhood Hits	586	Shared Neighborhood Hits	155
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MAP1B_MOUSE
NC score	0.190402 (rank : 505)	θ value	0.0113563 (rank : 163)
Query Neighborhood Hits	457	Target Neighborhood Hits	977	Shared Neighborhood Hits	153
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TACC3_HUMAN
NC score	0.190208 (rank : 506)	θ value	θ > 10 (rank : 1427)
Query Neighborhood Hits	457	Target Neighborhood Hits	779	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TCRG1_HUMAN
NC score	0.189883 (rank : 507)	θ value	θ > 10 (rank : 1448)
Query Neighborhood Hits	457	Target Neighborhood Hits	929	Shared Neighborhood Hits	185
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

APOA4_MOUSE
NC score	0.189505 (rank : 508)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	119
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

TCRG1_MOUSE
NC score	0.189411 (rank : 509)	θ value	θ > 10 (rank : 1449)
Query Neighborhood Hits	457	Target Neighborhood Hits	947	Shared Neighborhood Hits	186
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

SPTB2_MOUSE
NC score	0.188993 (rank : 510)	θ value	θ > 10 (rank : 1369)
Query Neighborhood Hits	457	Target Neighborhood Hits	770	Shared Neighborhood Hits	191
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

IASPP_MOUSE
NC score	0.188848 (rank : 511)	θ value	0.0431538 (rank : 195)
Query Neighborhood Hits	457	Target Neighborhood Hits	1024	Shared Neighborhood Hits	158
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TXLNG_MOUSE
NC score	0.188412 (rank : 512)	θ value	θ > 10 (rank : 1518)
Query Neighborhood Hits	457	Target Neighborhood Hits	552	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

ADIP_MOUSE
NC score	0.188145 (rank : 513)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	457	Target Neighborhood Hits	415	Shared Neighborhood Hits	154
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

CA065_HUMAN
NC score	0.188002 (rank : 514)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	457	Target Neighborhood Hits	469	Shared Neighborhood Hits	147
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

DDEF2_HUMAN
NC score	0.187937 (rank : 515)	θ value	0.0431538 (rank : 190)
Query Neighborhood Hits	457	Target Neighborhood Hits	599	Shared Neighborhood Hits	159
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.187658 (rank : 516)	θ value	0.125558 (rank : 234)
Query Neighborhood Hits	457	Target Neighborhood Hits	625	Shared Neighborhood Hits	157
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CCD93_MOUSE
NC score	0.187637 (rank : 517)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	457	Target Neighborhood Hits	362	Shared Neighborhood Hits	137
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

HAP1_HUMAN
NC score	0.187334 (rank : 518)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	457	Target Neighborhood Hits	606	Shared Neighborhood Hits	177
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

KIF5C_HUMAN
NC score	0.186846 (rank : 519)	θ value	0.00390308 (rank : 129)
Query Neighborhood Hits	457	Target Neighborhood Hits	974	Shared Neighborhood Hits	218
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

SPTB2_HUMAN
NC score	0.185956 (rank : 520)	θ value	θ > 10 (rank : 1368)
Query Neighborhood Hits	457	Target Neighborhood Hits	748	Shared Neighborhood Hits	187
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

T3JAM_MOUSE
NC score	0.185800 (rank : 521)	θ value	θ > 10 (rank : 1422)
Query Neighborhood Hits	457	Target Neighborhood Hits	535	Shared Neighborhood Hits	146
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TACC2_MOUSE
NC score	0.185724 (rank : 522)	θ value	θ > 10 (rank : 1426)
Query Neighborhood Hits	457	Target Neighborhood Hits	774	Shared Neighborhood Hits	181
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

RASF8_HUMAN
NC score	0.184090 (rank : 523)	θ value	θ > 10 (rank : 1250)
Query Neighborhood Hits	457	Target Neighborhood Hits	469	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

KIF5A_HUMAN
NC score	0.183895 (rank : 524)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	457	Target Neighborhood Hits	843	Shared Neighborhood Hits	200
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LIPB2_HUMAN
NC score	0.182912 (rank : 525)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	457	Target Neighborhood Hits	599	Shared Neighborhood Hits	158
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

AL2SB_HUMAN
NC score	0.182500 (rank : 526)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	457	Target Neighborhood Hits	294	Shared Neighborhood Hits	119
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

CEP35_HUMAN
NC score	0.182468 (rank : 527)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	457	Target Neighborhood Hits	811	Shared Neighborhood Hits	193
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

SPN90_HUMAN
NC score	0.182425 (rank : 528)	θ value	1.81305 (rank : 355)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

K0552_HUMAN
NC score	0.182373 (rank : 529)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	457	Target Neighborhood Hits	442	Shared Neighborhood Hits	133
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

BAIP2_MOUSE
NC score	0.182067 (rank : 530)	θ value	0.125558 (rank : 231)
Query Neighborhood Hits	457	Target Neighborhood Hits	185	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

KIF5A_MOUSE
NC score	0.182044 (rank : 531)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	457	Target Neighborhood Hits	859	Shared Neighborhood Hits	196
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

STIM1_HUMAN
NC score	0.181928 (rank : 532)	θ value	θ > 10 (rank : 1383)
Query Neighborhood Hits	457	Target Neighborhood Hits	665	Shared Neighborhood Hits	186
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

HOME2_HUMAN
NC score	0.181789 (rank : 533)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

MOES_MOUSE
NC score	0.181718 (rank : 534)	θ value	0.000602161 (rank : 92)
Query Neighborhood Hits	457	Target Neighborhood Hits	923	Shared Neighborhood Hits	202
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

LRRF1_HUMAN
NC score	0.181470 (rank : 535)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	457	Target Neighborhood Hits	625	Shared Neighborhood Hits	164
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

PININ_HUMAN
NC score	0.181258 (rank : 536)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	457	Target Neighborhood Hits	753	Shared Neighborhood Hits	179
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

STIM1_MOUSE
NC score	0.181084 (rank : 537)	θ value	θ > 10 (rank : 1384)
Query Neighborhood Hits	457	Target Neighborhood Hits	660	Shared Neighborhood Hits	193
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

LIPB2_MOUSE
NC score	0.180817 (rank : 538)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	457	Target Neighborhood Hits	570	Shared Neighborhood Hits	157
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

GP73_MOUSE
NC score	0.180579 (rank : 539)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	144
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

MORC3_HUMAN
NC score	0.179912 (rank : 540)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	457	Target Neighborhood Hits	489	Shared Neighborhood Hits	157
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

TEKT1_HUMAN
NC score	0.179311 (rank : 541)	θ value	θ > 10 (rank : 1452)
Query Neighborhood Hits	457	Target Neighborhood Hits	289	Shared Neighborhood Hits	128
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

BIN1_MOUSE
NC score	0.179060 (rank : 542)	θ value	0.365318 (rank : 270)
Query Neighborhood Hits	457	Target Neighborhood Hits	283	Shared Neighborhood Hits	103
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

SNX23_HUMAN
NC score	0.178845 (rank : 543)	θ value	0.62314 (rank : 305)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	193
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

IMMT_HUMAN
NC score	0.178766 (rank : 544)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	457	Target Neighborhood Hits	494	Shared Neighborhood Hits	157
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

RHG04_HUMAN
NC score	0.178763 (rank : 545)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	457	Target Neighborhood Hits	307	Shared Neighborhood Hits	152
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RASF8_MOUSE
NC score	0.178509 (rank : 546)	θ value	θ > 10 (rank : 1251)
Query Neighborhood Hits	457	Target Neighborhood Hits	391	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

PININ_MOUSE
NC score	0.178499 (rank : 547)	θ value	1.38821 (rank : 333)
Query Neighborhood Hits	457	Target Neighborhood Hits	777	Shared Neighborhood Hits	178
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

BAIP2_HUMAN
NC score	0.178256 (rank : 548)	θ value	0.125558 (rank : 230)
Query Neighborhood Hits	457	Target Neighborhood Hits	192	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

CAF1A_MOUSE
NC score	0.177965 (rank : 549)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	457	Target Neighborhood Hits	736	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

TXLNB_MOUSE
NC score	0.177466 (rank : 550)	θ value	θ > 10 (rank : 1517)
Query Neighborhood Hits	457	Target Neighborhood Hits	640	Shared Neighborhood Hits	150
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

WDR67_HUMAN
NC score	0.176833 (rank : 551)	θ value	θ > 10 (rank : 1539)
Query Neighborhood Hits	457	Target Neighborhood Hits	782	Shared Neighborhood Hits	173
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

CJ068_HUMAN
NC score	0.176285 (rank : 552)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	457	Target Neighborhood Hits	316	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

SRGP1_HUMAN
NC score	0.176093 (rank : 553)	θ value	θ > 10 (rank : 1373)
Query Neighborhood Hits	457	Target Neighborhood Hits	390	Shared Neighborhood Hits	182
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

BIN1_HUMAN
NC score	0.175068 (rank : 554)	θ value	0.365318 (rank : 269)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

MFAP1_MOUSE
NC score	0.174801 (rank : 555)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	457	Target Neighborhood Hits	353	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

VDP_MOUSE
NC score	0.174591 (rank : 556)	θ value	θ > 10 (rank : 1533)
Query Neighborhood Hits	457	Target Neighborhood Hits	469	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

PLVAP_HUMAN
NC score	0.174087 (rank : 557)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	457	Target Neighborhood Hits	397	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

NEB2_MOUSE
NC score	0.173317 (rank : 558)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	457	Target Neighborhood Hits	889	Shared Neighborhood Hits	187
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SDPR_MOUSE
NC score	0.173218 (rank : 559)	θ value	4.03905 (rank : 397)
Query Neighborhood Hits	457	Target Neighborhood Hits	485	Shared Neighborhood Hits	143
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SRGP2_MOUSE
NC score	0.172896 (rank : 560)	θ value	θ > 10 (rank : 1375)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	168
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SKIL_MOUSE
NC score	0.172865 (rank : 561)	θ value	θ > 10 (rank : 1338)
Query Neighborhood Hits	457	Target Neighborhood Hits	719	Shared Neighborhood Hits	193
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

LMNB1_MOUSE
NC score	0.171973 (rank : 562)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	457	Target Neighborhood Hits	719	Shared Neighborhood Hits	191
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

TXLNB_HUMAN
NC score	0.171926 (rank : 563)	θ value	θ > 10 (rank : 1516)
Query Neighborhood Hits	457	Target Neighborhood Hits	912	Shared Neighborhood Hits	168
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

K0494_HUMAN
NC score	0.171647 (rank : 564)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	457	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

CENPH_MOUSE
NC score	0.171644 (rank : 565)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	457	Target Neighborhood Hits	195	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

LMNB1_HUMAN
NC score	0.171612 (rank : 566)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	457	Target Neighborhood Hits	714	Shared Neighborhood Hits	191
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

HOME1_MOUSE
NC score	0.171410 (rank : 567)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	457	Target Neighborhood Hits	630	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

RBBP8_HUMAN
NC score	0.171357 (rank : 568)	θ value	θ > 10 (rank : 1252)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	141
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

KI21A_HUMAN
NC score	0.171323 (rank : 569)	θ value	0.163984 (rank : 247)
Query Neighborhood Hits	457	Target Neighborhood Hits	1543	Shared Neighborhood Hits	238
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

SRGP2_HUMAN
NC score	0.171309 (rank : 570)	θ value	θ > 10 (rank : 1374)
Query Neighborhood Hits	457	Target Neighborhood Hits	331	Shared Neighborhood Hits	166
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SPC24_HUMAN
NC score	0.171065 (rank : 571)	θ value	θ > 10 (rank : 1362)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

BRAP_HUMAN
NC score	0.171008 (rank : 572)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	457	Target Neighborhood Hits	560	Shared Neighborhood Hits	156
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

SH24A_HUMAN
NC score	0.170485 (rank : 573)	θ value	θ > 10 (rank : 1319)
Query Neighborhood Hits	457	Target Neighborhood Hits	455	Shared Neighborhood Hits	154
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

STXB4_HUMAN
NC score	0.170280 (rank : 574)	θ value	θ > 10 (rank : 1409)
Query Neighborhood Hits	457	Target Neighborhood Hits	616	Shared Neighborhood Hits	166
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

AMOL2_HUMAN
NC score	0.170141 (rank : 575)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	457	Target Neighborhood Hits	603	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

LMNB2_HUMAN
NC score	0.169983 (rank : 576)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	187
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

RENT2_HUMAN
NC score	0.169784 (rank : 577)	θ value	1.38821 (rank : 336)
Query Neighborhood Hits	457	Target Neighborhood Hits	618	Shared Neighborhood Hits	146
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

NEB2_HUMAN
NC score	0.169359 (rank : 578)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	457	Target Neighborhood Hits	883	Shared Neighborhood Hits	188
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFM_MOUSE
NC score	0.168353 (rank : 579)	θ value	0.0431538 (rank : 197)
Query Neighborhood Hits	457	Target Neighborhood Hits	1159	Shared Neighborhood Hits	224
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

HC127_HUMAN
NC score	0.168140 (rank : 580)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.168140 (rank : 581)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	111
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

SPN90_MOUSE
NC score	0.167429 (rank : 582)	θ value	1.38821 (rank : 339)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ROCK1_MOUSE
NC score	0.167351 (rank : 583)	θ value	0.00228821 (rank : 118)
Query Neighborhood Hits	457	Target Neighborhood Hits	2126	Shared Neighborhood Hits	278
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RASA1_HUMAN
NC score	0.167331 (rank : 584)	θ value	0.00390308 (rank : 133)
Query Neighborhood Hits	457	Target Neighborhood Hits	258	Shared Neighborhood Hits	76
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

NEB1_HUMAN
NC score	0.167138 (rank : 585)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	457	Target Neighborhood Hits	829	Shared Neighborhood Hits	185
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

CAF1A_HUMAN
NC score	0.167028 (rank : 586)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	457	Target Neighborhood Hits	750	Shared Neighborhood Hits	169
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

LZTS2_HUMAN
NC score	0.166999 (rank : 587)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	457	Target Neighborhood Hits	427	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

NFM_HUMAN
NC score	0.166626 (rank : 588)	θ value	0.0252991 (rank : 181)
Query Neighborhood Hits	457	Target Neighborhood Hits	1328	Shared Neighborhood Hits	231
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MOES_HUMAN
NC score	0.166606 (rank : 589)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	457	Target Neighborhood Hits	892	Shared Neighborhood Hits	201
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TTC3_HUMAN
NC score	0.166334 (rank : 590)	θ value	5.27518 (rank : 418)
Query Neighborhood Hits	457	Target Neighborhood Hits	664	Shared Neighborhood Hits	161
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

CENPK_HUMAN
NC score	0.166214 (rank : 591)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	457	Target Neighborhood Hits	273	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

HOME1_HUMAN
NC score	0.165547 (rank : 592)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	457	Target Neighborhood Hits	564	Shared Neighborhood Hits	157
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

K0494_MOUSE
NC score	0.165545 (rank : 593)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

LMNA_HUMAN
NC score	0.165429 (rank : 594)	θ value	0.0961366 (rank : 222)
Query Neighborhood Hits	457	Target Neighborhood Hits	653	Shared Neighborhood Hits	183
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
NC score	0.165346 (rank : 595)	θ value	0.163984 (rank : 249)
Query Neighborhood Hits	457	Target Neighborhood Hits	661	Shared Neighborhood Hits	185
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

AMOL2_MOUSE
NC score	0.165074 (rank : 596)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	457	Target Neighborhood Hits	591	Shared Neighborhood Hits	157
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

CTRO_MOUSE
NC score	0.165054 (rank : 597)	θ value	0.163984 (rank : 243)
Query Neighborhood Hits	457	Target Neighborhood Hits	2344	Shared Neighborhood Hits	283
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NGEF_MOUSE
NC score	0.164842 (rank : 598)	θ value	3.0926 (rank : 384)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

AMOT_HUMAN
NC score	0.164790 (rank : 599)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	457	Target Neighborhood Hits	712	Shared Neighborhood Hits	161
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

MRIP_MOUSE
NC score	0.164618 (rank : 600)	θ value	0.0961366 (rank : 224)
Query Neighborhood Hits	457	Target Neighborhood Hits	569	Shared Neighborhood Hits	148
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

JIP3_HUMAN
NC score	0.164433 (rank : 601)	θ value	0.00509761 (rank : 143)
Query Neighborhood Hits	457	Target Neighborhood Hits	1039	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MAP1B_HUMAN
NC score	0.164124 (rank : 602)	θ value	0.00134147 (rank : 107)
Query Neighborhood Hits	457	Target Neighborhood Hits	903	Shared Neighborhood Hits	139
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CAR10_HUMAN
NC score	0.164002 (rank : 603)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	457	Target Neighborhood Hits	569	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

ANR12_HUMAN
NC score	0.163966 (rank : 604)	θ value	0.0330416 (rank : 182)
Query Neighborhood Hits	457	Target Neighborhood Hits	1081	Shared Neighborhood Hits	199
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

STMN1_HUMAN
NC score	0.163931 (rank : 605)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	457	Target Neighborhood Hits	554	Shared Neighborhood Hits	169
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

APOE_MOUSE
NC score	0.163454 (rank : 606)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	457	Target Neighborhood Hits	319	Shared Neighborhood Hits	109
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

CLC4F_MOUSE
NC score	0.163261 (rank : 607)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	457	Target Neighborhood Hits	572	Shared Neighborhood Hits	144
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

MAP9_HUMAN
NC score	0.163199 (rank : 608)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	457	Target Neighborhood Hits	518	Shared Neighborhood Hits	144
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

ARHG4_MOUSE
NC score	0.163193 (rank : 609)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	457	Target Neighborhood Hits	185	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

LIPA3_MOUSE
NC score	0.162841 (rank : 610)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	457	Target Neighborhood Hits	636	Shared Neighborhood Hits	161
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

AMPH_HUMAN
NC score	0.162785 (rank : 611)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	457	Target Neighborhood Hits	455	Shared Neighborhood Hits	130
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

NDEL1_HUMAN
NC score	0.162648 (rank : 612)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	457	Target Neighborhood Hits	415	Shared Neighborhood Hits	129
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NGEF_HUMAN
NC score	0.162512 (rank : 613)	θ value	1.81305 (rank : 349)
Query Neighborhood Hits	457	Target Neighborhood Hits	166	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGG_MOUSE
NC score	0.162257 (rank : 614)	θ value	0.0736092 (rank : 206)
Query Neighborhood Hits	457	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

AMOL1_HUMAN
NC score	0.162211 (rank : 615)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	457	Target Neighborhood Hits	435	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

APOA4_HUMAN
NC score	0.161921 (rank : 616)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	457	Target Neighborhood Hits	399	Shared Neighborhood Hits	118
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

NDEL1_MOUSE
NC score	0.161891 (rank : 617)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	457	Target Neighborhood Hits	420	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

SPC25_HUMAN
NC score	0.161782 (rank : 618)	θ value	θ > 10 (rank : 1364)
Query Neighborhood Hits	457	Target Neighborhood Hits	273	Shared Neighborhood Hits	121
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

LMNB2_MOUSE
NC score	0.161010 (rank : 619)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	457	Target Neighborhood Hits	674	Shared Neighborhood Hits	186
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

STMN1_MOUSE
NC score	0.160593 (rank : 620)	θ value	θ > 10 (rank : 1389)
Query Neighborhood Hits	457	Target Neighborhood Hits	560	Shared Neighborhood Hits	167
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

NOP14_HUMAN
NC score	0.160560 (rank : 621)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	457	Target Neighborhood Hits	573	Shared Neighborhood Hits	167
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

KIF11_HUMAN
NC score	0.160042 (rank : 622)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	457	Target Neighborhood Hits	583	Shared Neighborhood Hits	173
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

CCDC7_HUMAN
NC score	0.159586 (rank : 623)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	457	Target Neighborhood Hits	253	Shared Neighborhood Hits	98
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

LETM1_HUMAN
NC score	0.159039 (rank : 624)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	457	Target Neighborhood Hits	338	Shared Neighborhood Hits	111
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

JIP3_MOUSE
NC score	0.158884 (rank : 625)	θ value	3.0926 (rank : 380)
Query Neighborhood Hits	457	Target Neighborhood Hits	759	Shared Neighborhood Hits	183
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

ES8L3_MOUSE
NC score	0.158359 (rank : 626)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	457	Target Neighborhood Hits	168	Shared Neighborhood Hits	118
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

MRIP_HUMAN
NC score	0.157808 (rank : 627)	θ value	1.38821 (rank : 330)
Query Neighborhood Hits	457	Target Neighborhood Hits	578	Shared Neighborhood Hits	142
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRCKB_MOUSE
NC score	0.157200 (rank : 628)	θ value	0.0736092 (rank : 211)
Query Neighborhood Hits	457	Target Neighborhood Hits	2180	Shared Neighborhood Hits	286
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ROCK1_HUMAN
NC score	0.156535 (rank : 629)	θ value	0.000786445 (rank : 100)
Query Neighborhood Hits	457	Target Neighborhood Hits	2000	Shared Neighborhood Hits	261
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

GP73_HUMAN
NC score	0.155596 (rank : 630)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	457	Target Neighborhood Hits	309	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

MMRN2_HUMAN
NC score	0.155487 (rank : 631)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	457	Target Neighborhood Hits	400	Shared Neighborhood Hits	121
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

CTRO_HUMAN
NC score	0.154693 (rank : 632)	θ value	0.00102713 (rank : 102)
Query Neighborhood Hits	457	Target Neighborhood Hits	2092	Shared Neighborhood Hits	262
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SEC20_MOUSE
NC score	0.154145 (rank : 633)	θ value	θ > 10 (rank : 1306)
Query Neighborhood Hits	457	Target Neighborhood Hits	323	Shared Neighborhood Hits	117
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

RPGR1_MOUSE
NC score	0.154045 (rank : 634)	θ value	θ > 10 (rank : 1277)
Query Neighborhood Hits	457	Target Neighborhood Hits	713	Shared Neighborhood Hits	160
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CDC37_HUMAN
NC score	0.154023 (rank : 635)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	155
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

DREB_MOUSE
NC score	0.153938 (rank : 636)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	120
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

AMPH_MOUSE
NC score	0.153675 (rank : 637)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	457	Target Neighborhood Hits	291	Shared Neighborhood Hits	118
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

MRCKB_HUMAN
NC score	0.153544 (rank : 638)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	457	Target Neighborhood Hits	2239	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SNX9_HUMAN
NC score	0.153438 (rank : 639)	θ value	θ > 10 (rank : 1355)
Query Neighborhood Hits	457	Target Neighborhood Hits	148	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

OLR1_MOUSE
NC score	0.153402 (rank : 640)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	457	Target Neighborhood Hits	596	Shared Neighborhood Hits	144
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

NTBP1_MOUSE
NC score	0.153143 (rank : 641)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	457	Target Neighborhood Hits	528	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

GLE1_HUMAN
NC score	0.152494 (rank : 642)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	457	Target Neighborhood Hits	445	Shared Neighborhood Hits	136
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

MFAP1_HUMAN
NC score	0.152067 (rank : 643)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	120
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

PLCB2_HUMAN
NC score	0.151889 (rank : 644)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	457	Target Neighborhood Hits	608	Shared Neighborhood Hits	182
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

CAR14_MOUSE
NC score	0.151869 (rank : 645)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	145
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

DREB_HUMAN
NC score	0.151744 (rank : 646)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	457	Target Neighborhood Hits	450	Shared Neighborhood Hits	132
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GLE1_MOUSE
NC score	0.151707 (rank : 647)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

ROCK2_MOUSE
NC score	0.151408 (rank : 648)	θ value	θ > 10 (rank : 1274)
Query Neighborhood Hits	457	Target Neighborhood Hits	2072	Shared Neighborhood Hits	269
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

KIF23_HUMAN
NC score	0.151343 (rank : 649)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	457	Target Neighborhood Hits	618	Shared Neighborhood Hits	178
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

SFR12_HUMAN
NC score	0.151296 (rank : 650)	θ value	0.0330416 (rank : 186)
Query Neighborhood Hits	457	Target Neighborhood Hits	553	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

LZTS2_MOUSE
NC score	0.151208 (rank : 651)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	121
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

CAR14_HUMAN
NC score	0.150661 (rank : 652)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	457	Target Neighborhood Hits	449	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

STXB4_MOUSE
NC score	0.150362 (rank : 653)	θ value	θ > 10 (rank : 1410)
Query Neighborhood Hits	457	Target Neighborhood Hits	629	Shared Neighborhood Hits	162
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

BCN1_HUMAN
NC score	0.150236 (rank : 654)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	140
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

RADI_HUMAN
NC score	0.149498 (rank : 655)	θ value	4.03905 (rank : 396)
Query Neighborhood Hits	457	Target Neighborhood Hits	741	Shared Neighborhood Hits	188
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

DYHC_HUMAN
NC score	0.148920 (rank : 656)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	457	Target Neighborhood Hits	733	Shared Neighborhood Hits	199
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.148673 (rank : 657)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	457	Target Neighborhood Hits	729	Shared Neighborhood Hits	199
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

ROCK2_HUMAN
NC score	0.148587 (rank : 658)	θ value	θ > 10 (rank : 1273)
Query Neighborhood Hits	457	Target Neighborhood Hits	2073	Shared Neighborhood Hits	273
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

KI21A_MOUSE
NC score	0.148487 (rank : 659)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	457	Target Neighborhood Hits	1317	Shared Neighborhood Hits	224
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

NUP88_HUMAN
NC score	0.148482 (rank : 660)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	457	Target Neighborhood Hits	354	Shared Neighborhood Hits	128
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

BI2L1_HUMAN
NC score	0.148477 (rank : 661)	θ value	5.27518 (rank : 400)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

PRC1_MOUSE
NC score	0.148456 (rank : 662)	θ value	θ > 10 (rank : 1238)
Query Neighborhood Hits	457	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

BAP29_HUMAN
NC score	0.148456 (rank : 663)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	457	Target Neighborhood Hits	362	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

IDLC_HUMAN
NC score	0.148282 (rank : 664)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	127
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

CCD42_MOUSE
NC score	0.148026 (rank : 665)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	457	Target Neighborhood Hits	284	Shared Neighborhood Hits	114
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

SPTB1_MOUSE
NC score	0.147773 (rank : 666)	θ value	θ > 10 (rank : 1367)
Query Neighborhood Hits	457	Target Neighborhood Hits	543	Shared Neighborhood Hits	162
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

CYLC2_HUMAN
NC score	0.147710 (rank : 667)	θ value	0.00035302 (rank : 81)
Query Neighborhood Hits	457	Target Neighborhood Hits	223	Shared Neighborhood Hits	50
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

LRSM1_HUMAN
NC score	0.146604 (rank : 668)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	457	Target Neighborhood Hits	1078	Shared Neighborhood Hits	187
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SLAP2_MOUSE
NC score	0.146284 (rank : 669)	θ value	θ > 10 (rank : 1344)
Query Neighborhood Hits	457	Target Neighborhood Hits	136	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

DOCK1_HUMAN
NC score	0.145706 (rank : 670)	θ value	0.0431538 (rank : 192)
Query Neighborhood Hits	457	Target Neighborhood Hits	191	Shared Neighborhood Hits	118
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DZIP1_HUMAN
NC score	0.145705 (rank : 671)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	457	Target Neighborhood Hits	675	Shared Neighborhood Hits	118
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

AMOL1_MOUSE
NC score	0.145651 (rank : 672)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	457	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

SLAP2_HUMAN
NC score	0.145628 (rank : 673)	θ value	θ > 10 (rank : 1343)
Query Neighborhood Hits	457	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

MRCKA_HUMAN
NC score	0.145577 (rank : 674)	θ value	0.00390308 (rank : 130)
Query Neighborhood Hits	457	Target Neighborhood Hits	1999	Shared Neighborhood Hits	260
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MYO7A_MOUSE
NC score	0.145510 (rank : 675)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	82
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

PRC1_HUMAN
NC score	0.145153 (rank : 676)	θ value	θ > 10 (rank : 1237)
Query Neighborhood Hits	457	Target Neighborhood Hits	328	Shared Neighborhood Hits	117
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

SPTB1_HUMAN
NC score	0.144999 (rank : 677)	θ value	θ > 10 (rank : 1366)
Query Neighborhood Hits	457	Target Neighborhood Hits	541	Shared Neighborhood Hits	151
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

BAP29_MOUSE
NC score	0.144892 (rank : 678)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	457	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

ARHGG_HUMAN
NC score	0.144861 (rank : 679)	θ value	0.00509761 (rank : 140)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CCD38_HUMAN
NC score	0.144687 (rank : 680)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	457	Target Neighborhood Hits	287	Shared Neighborhood Hits	118
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

ZWINT_HUMAN
NC score	0.144452 (rank : 681)	θ value	θ > 10 (rank : 1563)
Query Neighborhood Hits	457	Target Neighborhood Hits	333	Shared Neighborhood Hits	120
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

BFSP1_HUMAN
NC score	0.144246 (rank : 682)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	457	Target Neighborhood Hits	508	Shared Neighborhood Hits	152
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

BCN1_MOUSE
NC score	0.144103 (rank : 683)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	457	Target Neighborhood Hits	367	Shared Neighborhood Hits	130
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

MPP8_HUMAN
NC score	0.144031 (rank : 684)	θ value	0.0113563 (rank : 164)
Query Neighborhood Hits	457	Target Neighborhood Hits	948	Shared Neighborhood Hits	177
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

GAS7_HUMAN
NC score	0.143995 (rank : 685)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	457	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

ZRF1_MOUSE
NC score	0.143669 (rank : 686)	θ value	θ > 10 (rank : 1562)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	122
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

TARA_MOUSE
NC score	0.143587 (rank : 687)	θ value	θ > 10 (rank : 1440)
Query Neighborhood Hits	457	Target Neighborhood Hits	1133	Shared Neighborhood Hits	180
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHLB1_HUMAN
NC score	0.143575 (rank : 688)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	457	Target Neighborhood Hits	1038	Shared Neighborhood Hits	188
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

LBN_HUMAN
NC score	0.143523 (rank : 689)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	457	Target Neighborhood Hits	308	Shared Neighborhood Hits	111
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

BI2L1_MOUSE
NC score	0.143466 (rank : 690)	θ value	4.03905 (rank : 389)
Query Neighborhood Hits	457	Target Neighborhood Hits	197	Shared Neighborhood Hits	87
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

PLCB1_HUMAN
NC score	0.143336 (rank : 691)	θ value	5.27518 (rank : 412)
Query Neighborhood Hits	457	Target Neighborhood Hits	614	Shared Neighborhood Hits	175
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RADI_MOUSE
NC score	0.143011 (rank : 692)	θ value	θ > 10 (rank : 1249)
Query Neighborhood Hits	457	Target Neighborhood Hits	773	Shared Neighborhood Hits	180
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MPP10_MOUSE
NC score	0.141955 (rank : 693)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	457	Target Neighborhood Hits	251	Shared Neighborhood Hits	104
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

ZC313_HUMAN
NC score	0.141850 (rank : 694)	θ value	6.88961 (rank : 436)
Query Neighborhood Hits	457	Target Neighborhood Hits	772	Shared Neighborhood Hits	157
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

DIAP1_MOUSE
NC score	0.141618 (rank : 695)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	457	Target Neighborhood Hits	839	Shared Neighborhood Hits	178
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

ES8L3_HUMAN
NC score	0.141607 (rank : 696)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	107
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

LAMA2_MOUSE
NC score	0.141365 (rank : 697)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	457	Target Neighborhood Hits	1198	Shared Neighborhood Hits	187
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MPP10_HUMAN
NC score	0.141269 (rank : 698)	θ value	3.0926 (rank : 383)
Query Neighborhood Hits	457	Target Neighborhood Hits	306	Shared Neighborhood Hits	105
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MYO7A_HUMAN
NC score	0.141226 (rank : 699)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	457	Target Neighborhood Hits	209	Shared Neighborhood Hits	72
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

EZRI_MOUSE
NC score	0.140794 (rank : 700)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	457	Target Neighborhood Hits	693	Shared Neighborhood Hits	183
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CN045_HUMAN
NC score	0.139726 (rank : 701)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	102
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

FYN_MOUSE
NC score	0.139712 (rank : 702)	θ value	5.44631e-05 (rank : 56)
Query Neighborhood Hits	457	Target Neighborhood Hits	1073	Shared Neighborhood Hits	168
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

SKIL_HUMAN
NC score	0.139619 (rank : 703)	θ value	θ > 10 (rank : 1337)
Query Neighborhood Hits	457	Target Neighborhood Hits	460	Shared Neighborhood Hits	141
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

LBN_MOUSE
NC score	0.139519 (rank : 704)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	114
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

SDPR_HUMAN
NC score	0.139299 (rank : 705)	θ value	θ > 10 (rank : 1302)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	108
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

KIFC3_MOUSE
NC score	0.139280 (rank : 706)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	457	Target Neighborhood Hits	571	Shared Neighborhood Hits	163
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_HUMAN
NC score	0.139240 (rank : 707)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	457	Target Neighborhood Hits	619	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

IDLC_MOUSE
NC score	0.138926 (rank : 708)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

HAP1_MOUSE
NC score	0.138724 (rank : 709)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	457	Target Neighborhood Hits	388	Shared Neighborhood Hits	114
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

EMIL2_HUMAN
NC score	0.138645 (rank : 710)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	457	Target Neighborhood Hits	573	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

SNX9_MOUSE
NC score	0.138447 (rank : 711)	θ value	θ > 10 (rank : 1356)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

M3KL4_HUMAN
NC score	0.138166 (rank : 712)	θ value	0.000158464 (rank : 75)
Query Neighborhood Hits	457	Target Neighborhood Hits	1087	Shared Neighborhood Hits	210
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

FA50A_MOUSE
NC score	0.137992 (rank : 713)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	457	Target Neighborhood Hits	293	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

CLUA1_MOUSE
NC score	0.137744 (rank : 714)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	457	Target Neighborhood Hits	261	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

SLAP1_HUMAN
NC score	0.137704 (rank : 715)	θ value	θ > 10 (rank : 1341)
Query Neighborhood Hits	457	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

FYN_HUMAN
NC score	0.137521 (rank : 716)	θ value	5.44631e-05 (rank : 55)
Query Neighborhood Hits	457	Target Neighborhood Hits	1078	Shared Neighborhood Hits	168
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

EZRI_HUMAN
NC score	0.137364 (rank : 717)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	457	Target Neighborhood Hits	663	Shared Neighborhood Hits	175
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

SLAP1_MOUSE
NC score	0.137277 (rank : 718)	θ value	θ > 10 (rank : 1342)
Query Neighborhood Hits	457	Target Neighborhood Hits	117	Shared Neighborhood Hits	45
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

NOXO1_HUMAN
NC score	0.137102 (rank : 719)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	457	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

ARI4A_HUMAN
NC score	0.137091 (rank : 720)	θ value	0.62314 (rank : 295)
Query Neighborhood Hits	457	Target Neighborhood Hits	434	Shared Neighborhood Hits	106
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

TNNT2_HUMAN
NC score	0.136948 (rank : 721)	θ value	θ > 10 (rank : 1480)
Query Neighborhood Hits	457	Target Neighborhood Hits	433	Shared Neighborhood Hits	133
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

MYO15_MOUSE
NC score	0.136843 (rank : 722)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	457	Target Neighborhood Hits	467	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

JIP2_MOUSE
NC score	0.136812 (rank : 723)	θ value	0.279714 (rank : 264)
Query Neighborhood Hits	457	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_HUMAN
NC score	0.136547 (rank : 724)	θ value	0.279714 (rank : 263)
Query Neighborhood Hits	457	Target Neighborhood Hits	288	Shared Neighborhood Hits	71
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TNNT3_MOUSE
NC score	0.135997 (rank : 725)	θ value	θ > 10 (rank : 1483)
Query Neighborhood Hits	457	Target Neighborhood Hits	317	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

MAP9_MOUSE
NC score	0.135774 (rank : 726)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	457	Target Neighborhood Hits	529	Shared Neighborhood Hits	127
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SRC_HUMAN
NC score	0.135747 (rank : 727)	θ value	9.29e-05 (rank : 69)
Query Neighborhood Hits	457	Target Neighborhood Hits	1058	Shared Neighborhood Hits	166
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

TNNT3_HUMAN
NC score	0.135645 (rank : 728)	θ value	θ > 10 (rank : 1482)
Query Neighborhood Hits	457	Target Neighborhood Hits	327	Shared Neighborhood Hits	117
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

FGR_HUMAN
NC score	0.135283 (rank : 729)	θ value	0.00390308 (rank : 127)
Query Neighborhood Hits	457	Target Neighborhood Hits	1067	Shared Neighborhood Hits	166
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

COVA1_HUMAN
NC score	0.135276 (rank : 730)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	457	Target Neighborhood Hits	416	Shared Neighborhood Hits	120
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SSNA1_MOUSE
NC score	0.135163 (rank : 731)	θ value	θ > 10 (rank : 1378)
Query Neighborhood Hits	457	Target Neighborhood Hits	182	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

ZRF1_HUMAN
NC score	0.135131 (rank : 732)	θ value	θ > 10 (rank : 1561)
Query Neighborhood Hits	457	Target Neighborhood Hits	457	Shared Neighborhood Hits	127
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

VIME_MOUSE
NC score	0.134778 (rank : 733)	θ value	θ > 10 (rank : 1535)
Query Neighborhood Hits	457	Target Neighborhood Hits	716	Shared Neighborhood Hits	184
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

KI21B_MOUSE
NC score	0.134528 (rank : 734)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	457	Target Neighborhood Hits	997	Shared Neighborhood Hits	184
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

SKI_MOUSE
NC score	0.134463 (rank : 735)	θ value	θ > 10 (rank : 1340)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	132
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

INVO_MOUSE
NC score	0.134397 (rank : 736)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	457	Target Neighborhood Hits	474	Shared Neighborhood Hits	116
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

MYO1D_HUMAN
NC score	0.134087 (rank : 737)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	457	Target Neighborhood Hits	56	Shared Neighborhood Hits	25
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1D_MOUSE
NC score	0.134054 (rank : 738)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	457	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

KIF3A_HUMAN
NC score	0.133922 (rank : 739)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	457	Target Neighborhood Hits	704	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYO1C_MOUSE
NC score	0.133844 (rank : 740)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	457	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

HAPIP_HUMAN
NC score	0.133657 (rank : 741)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	457	Target Neighborhood Hits	350	Shared Neighborhood Hits	111
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

MYO1C_HUMAN
NC score	0.133653 (rank : 742)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	457	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1A_HUMAN
NC score	0.133555 (rank : 743)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	457	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

KIF3A_MOUSE
NC score	0.133161 (rank : 744)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	457	Target Neighborhood Hits	715	Shared Neighborhood Hits	182
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

GFAP_HUMAN
NC score	0.133060 (rank : 745)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	184
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

IMMT_MOUSE
NC score	0.132973 (rank : 746)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	457	Target Neighborhood Hits	326	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

PLCB1_MOUSE
NC score	0.132889 (rank : 747)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	457	Target Neighborhood Hits	531	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

MYO1B_HUMAN
NC score	0.132696 (rank : 748)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	457	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1B_MOUSE
NC score	0.132517 (rank : 749)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	457	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

CCD22_MOUSE
NC score	0.132415 (rank : 750)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	457	Target Neighborhood Hits	268	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

YES_MOUSE
NC score	0.132157 (rank : 751)	θ value	0.00665767 (rank : 155)
Query Neighborhood Hits	457	Target Neighborhood Hits	1052	Shared Neighborhood Hits	162
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

MYO15_HUMAN
NC score	0.132045 (rank : 752)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	457	Target Neighborhood Hits	671	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

KI21B_HUMAN
NC score	0.131866 (rank : 753)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	457	Target Neighborhood Hits	1017	Shared Neighborhood Hits	189
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

CENPU_HUMAN
NC score	0.131657 (rank : 754)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	457	Target Neighborhood Hits	289	Shared Neighborhood Hits	118
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

LAMA4_HUMAN
NC score	0.131423 (rank : 755)	θ value	5.27518 (rank : 407)
Query Neighborhood Hits	457	Target Neighborhood Hits	708	Shared Neighborhood Hits	164
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

CTTB2_HUMAN
NC score	0.131359 (rank : 756)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	457	Target Neighborhood Hits	1061	Shared Neighborhood Hits	204
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

GFAP_MOUSE
NC score	0.131335 (rank : 757)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	457	Target Neighborhood Hits	725	Shared Neighborhood Hits	190
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

JIP4_HUMAN
NC score	0.131169 (rank : 758)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	457	Target Neighborhood Hits	585	Shared Neighborhood Hits	152
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

RGNEF_MOUSE
NC score	0.131156 (rank : 759)	θ value	θ > 10 (rank : 1262)
Query Neighborhood Hits	457	Target Neighborhood Hits	641	Shared Neighborhood Hits	169
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

YES_HUMAN
NC score	0.130924 (rank : 760)	θ value	0.00869519 (rank : 161)
Query Neighborhood Hits	457	Target Neighborhood Hits	1059	Shared Neighborhood Hits	162
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

K0586_HUMAN
NC score	0.130827 (rank : 761)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	457	Target Neighborhood Hits	311	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

K2C1_HUMAN
NC score	0.130751 (rank : 762)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	457	Target Neighborhood Hits	624	Shared Neighborhood Hits	176
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

VIME_HUMAN
NC score	0.130375 (rank : 763)	θ value	θ > 10 (rank : 1534)
Query Neighborhood Hits	457	Target Neighborhood Hits	706	Shared Neighborhood Hits	182
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

CCD22_HUMAN
NC score	0.129189 (rank : 764)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	457	Target Neighborhood Hits	242	Shared Neighborhood Hits	96
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

FGR_MOUSE
NC score	0.128997 (rank : 765)	θ value	0.21417 (rank : 255)
Query Neighborhood Hits	457	Target Neighborhood Hits	1069	Shared Neighborhood Hits	165
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

MYO9B_HUMAN
NC score	0.128852 (rank : 766)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	457	Target Neighborhood Hits	641	Shared Neighborhood Hits	78
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

KIF11_MOUSE
NC score	0.128535 (rank : 767)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	140
SwissProt Accessions	Q6P9P6, Q9Z1J0	Gene names	Kif11
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5).

TARA_HUMAN
NC score	0.128443 (rank : 768)	θ value	θ > 10 (rank : 1439)
Query Neighborhood Hits	457	Target Neighborhood Hits	1626	Shared Neighborhood Hits	195
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

A20A4_HUMAN
NC score	0.128395 (rank : 769)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	457	Target Neighborhood Hits	710	Shared Neighborhood Hits	155
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ENAH_HUMAN
NC score	0.128317 (rank : 770)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	457	Target Neighborhood Hits	784	Shared Neighborhood Hits	165
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CTGE4_HUMAN
NC score	0.128191 (rank : 771)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	457	Target Neighborhood Hits	393	Shared Neighborhood Hits	136
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

KIF14_HUMAN
NC score	0.128153 (rank : 772)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	457	Target Neighborhood Hits	732	Shared Neighborhood Hits	189
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

STIM2_HUMAN
NC score	0.127862 (rank : 773)	θ value	θ > 10 (rank : 1385)
Query Neighborhood Hits	457	Target Neighborhood Hits	420	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

TNNT2_MOUSE
NC score	0.127615 (rank : 774)	θ value	θ > 10 (rank : 1481)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	126
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

GAS7_MOUSE
NC score	0.127406 (rank : 775)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	457	Target Neighborhood Hits	259	Shared Neighborhood Hits	93
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

SKI_HUMAN
NC score	0.127287 (rank : 776)	θ value	θ > 10 (rank : 1339)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	132
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

JIP4_MOUSE
NC score	0.127040 (rank : 777)	θ value	2.36792 (rank : 366)
Query Neighborhood Hits	457	Target Neighborhood Hits	593	Shared Neighborhood Hits	155
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

CASC5_HUMAN
NC score	0.126937 (rank : 778)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	457	Target Neighborhood Hits	376	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

MYO9B_MOUSE
NC score	0.126734 (rank : 779)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	457	Target Neighborhood Hits	311	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SSNA1_HUMAN
NC score	0.126297 (rank : 780)	θ value	θ > 10 (rank : 1377)
Query Neighborhood Hits	457	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	O43805, Q6FG70, Q9BVW8	Gene names	SSNA1, NA14
Domain Architecture
Description	Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa).

NASP_HUMAN
NC score	0.126290 (rank : 781)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	457	Target Neighborhood Hits	709	Shared Neighborhood Hits	142
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SHAN2_MOUSE
NC score	0.126088 (rank : 782)	θ value	θ > 10 (rank : 1323)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	99
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

LAMA3_HUMAN
NC score	0.125892 (rank : 783)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	457	Target Neighborhood Hits	760	Shared Neighborhood Hits	140
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

CAR10_MOUSE
NC score	0.125681 (rank : 784)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	457	Target Neighborhood Hits	407	Shared Neighborhood Hits	129
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

STK10_MOUSE
NC score	0.125560 (rank : 785)	θ value	5.27518 (rank : 416)
Query Neighborhood Hits	457	Target Neighborhood Hits	2132	Shared Neighborhood Hits	269
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

LRSM1_MOUSE
NC score	0.125349 (rank : 786)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	457	Target Neighborhood Hits	874	Shared Neighborhood Hits	160
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

SPC25_MOUSE
NC score	0.125347 (rank : 787)	θ value	θ > 10 (rank : 1365)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	98
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

A20A1_HUMAN
NC score	0.124909 (rank : 788)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	457	Target Neighborhood Hits	698	Shared Neighborhood Hits	153
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

CDC37_MOUSE
NC score	0.124850 (rank : 789)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	133
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CUTL2_HUMAN
NC score	0.124677 (rank : 790)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	457	Target Neighborhood Hits	906	Shared Neighborhood Hits	151
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

BEGIN_HUMAN
NC score	0.124674 (rank : 791)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	457	Target Neighborhood Hits	454	Shared Neighborhood Hits	135
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

A20A2_HUMAN
NC score	0.124596 (rank : 792)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	457	Target Neighborhood Hits	716	Shared Neighborhood Hits	151
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

STIM2_MOUSE
NC score	0.124460 (rank : 793)	θ value	θ > 10 (rank : 1386)
Query Neighborhood Hits	457	Target Neighborhood Hits	403	Shared Neighborhood Hits	149
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

KIFC1_HUMAN
NC score	0.124313 (rank : 794)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	457	Target Neighborhood Hits	545	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

A20A3_HUMAN
NC score	0.124178 (rank : 795)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	457	Target Neighborhood Hits	692	Shared Neighborhood Hits	153
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

CEP72_MOUSE
NC score	0.123962 (rank : 796)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	457	Target Neighborhood Hits	381	Shared Neighborhood Hits	107
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

K0831_MOUSE
NC score	0.123447 (rank : 797)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	457	Target Neighborhood Hits	277	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

ES8L2_HUMAN
NC score	0.122689 (rank : 798)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	457	Target Neighborhood Hits	193	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

CCAR1_HUMAN
NC score	0.122633 (rank : 799)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	457	Target Neighborhood Hits	444	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

DZIP1_MOUSE
NC score	0.122572 (rank : 800)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	457	Target Neighborhood Hits	530	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

ATRX_HUMAN
NC score	0.122549 (rank : 801)	θ value	0.0431538 (rank : 188)
Query Neighborhood Hits	457	Target Neighborhood Hits	842	Shared Neighborhood Hits	165
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CHCH3_MOUSE
NC score	0.122119 (rank : 802)	θ value	0.365318 (rank : 273)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

NUCB1_MOUSE
NC score	0.122077 (rank : 803)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	122
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB2_MOUSE
NC score	0.121384 (rank : 804)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	457	Target Neighborhood Hits	459	Shared Neighborhood Hits	137
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

TAF7_HUMAN
NC score	0.121129 (rank : 805)	θ value	θ > 10 (rank : 1432)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	98
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

SRC_MOUSE
NC score	0.121005 (rank : 806)	θ value	0.00134147 (rank : 109)
Query Neighborhood Hits	457	Target Neighborhood Hits	1033	Shared Neighborhood Hits	156
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

PHLB3_HUMAN
NC score	0.120773 (rank : 807)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	457	Target Neighborhood Hits	304	Shared Neighborhood Hits	88
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

MERL_MOUSE
NC score	0.120731 (rank : 808)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	457	Target Neighborhood Hits	524	Shared Neighborhood Hits	155
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

WTAP_HUMAN
NC score	0.120466 (rank : 809)	θ value	θ > 10 (rank : 1541)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	92
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

ABTAP_MOUSE
NC score	0.120326 (rank : 810)	θ value	2.36792 (rank : 360)
Query Neighborhood Hits	457	Target Neighborhood Hits	381	Shared Neighborhood Hits	101
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

KIF3B_MOUSE
NC score	0.120179 (rank : 811)	θ value	0.0961366 (rank : 220)
Query Neighborhood Hits	457	Target Neighborhood Hits	533	Shared Neighborhood Hits	154
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

STMN2_HUMAN
NC score	0.120119 (rank : 812)	θ value	θ > 10 (rank : 1390)
Query Neighborhood Hits	457	Target Neighborhood Hits	458	Shared Neighborhood Hits	138
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.120119 (rank : 813)	θ value	θ > 10 (rank : 1391)
Query Neighborhood Hits	457	Target Neighborhood Hits	458	Shared Neighborhood Hits	138
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

TAF7_MOUSE
NC score	0.119952 (rank : 814)	θ value	θ > 10 (rank : 1433)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

LAMA2_HUMAN
NC score	0.119925 (rank : 815)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	457	Target Neighborhood Hits	1092	Shared Neighborhood Hits	168
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ZN318_MOUSE
NC score	0.119887 (rank : 816)	θ value	θ > 10 (rank : 1557)
Query Neighborhood Hits	457	Target Neighborhood Hits	642	Shared Neighborhood Hits	152
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

K2C8_HUMAN
NC score	0.119817 (rank : 817)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	457	Target Neighborhood Hits	593	Shared Neighborhood Hits	166
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

AMRP_MOUSE
NC score	0.119623 (rank : 818)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	457	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	P55302	Gene names	Lrpap1
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin-binding protein 44) (HBP-44).

ES8L2_MOUSE
NC score	0.119485 (rank : 819)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	457	Target Neighborhood Hits	169	Shared Neighborhood Hits	110
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

MERL_HUMAN
NC score	0.119483 (rank : 820)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	457	Target Neighborhood Hits	532	Shared Neighborhood Hits	153
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FA50A_HUMAN
NC score	0.119421 (rank : 821)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	457	Target Neighborhood Hits	264	Shared Neighborhood Hits	100
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

KIF3B_HUMAN
NC score	0.119176 (rank : 822)	θ value	0.279714 (rank : 265)
Query Neighborhood Hits	457	Target Neighborhood Hits	540	Shared Neighborhood Hits	154
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

JIP1_MOUSE
NC score	0.119012 (rank : 823)	θ value	0.62314 (rank : 300)
Query Neighborhood Hits	457	Target Neighborhood Hits	259	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

WTAP_MOUSE
NC score	0.118930 (rank : 824)	θ value	θ > 10 (rank : 1542)
Query Neighborhood Hits	457	Target Neighborhood Hits	250	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

K2C8_MOUSE
NC score	0.118681 (rank : 825)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	457	Target Neighborhood Hits	576	Shared Neighborhood Hits	175
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

BRAP_MOUSE
NC score	0.118664 (rank : 826)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	120
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

PLCB3_HUMAN
NC score	0.118583 (rank : 827)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	457	Target Neighborhood Hits	445	Shared Neighborhood Hits	137
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

SH24A_MOUSE
NC score	0.118431 (rank : 828)	θ value	θ > 10 (rank : 1320)
Query Neighborhood Hits	457	Target Neighborhood Hits	326	Shared Neighborhood Hits	117
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SEC20_HUMAN
NC score	0.118408 (rank : 829)	θ value	θ > 10 (rank : 1305)
Query Neighborhood Hits	457	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

TS101_HUMAN
NC score	0.118338 (rank : 830)	θ value	θ > 10 (rank : 1503)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	116
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

LETM1_MOUSE
NC score	0.118241 (rank : 831)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	457	Target Neighborhood Hits	240	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LAMB1_HUMAN
NC score	0.117755 (rank : 832)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	457	Target Neighborhood Hits	1018	Shared Neighborhood Hits	180
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BEGIN_MOUSE
NC score	0.117232 (rank : 833)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	457	Target Neighborhood Hits	383	Shared Neighborhood Hits	134
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BAZ1A_HUMAN
NC score	0.117066 (rank : 834)	θ value	0.47712 (rank : 286)
Query Neighborhood Hits	457	Target Neighborhood Hits	693	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

RBP1_HUMAN
NC score	0.116943 (rank : 835)	θ value	θ > 10 (rank : 1256)
Query Neighborhood Hits	457	Target Neighborhood Hits	521	Shared Neighborhood Hits	145
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

HCK_MOUSE
NC score	0.116907 (rank : 836)	θ value	0.0113563 (rank : 162)
Query Neighborhood Hits	457	Target Neighborhood Hits	1029	Shared Neighborhood Hits	161
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

JIP1_HUMAN
NC score	0.116868 (rank : 837)	θ value	0.813845 (rank : 314)
Query Neighborhood Hits	457	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

RBBP6_HUMAN
NC score	0.116845 (rank : 838)	θ value	1.38821 (rank : 334)
Query Neighborhood Hits	457	Target Neighborhood Hits	1135	Shared Neighborhood Hits	139
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

DIAP1_HUMAN
NC score	0.116744 (rank : 839)	θ value	0.365318 (rank : 276)
Query Neighborhood Hits	457	Target Neighborhood Hits	784	Shared Neighborhood Hits	162
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

CUTL2_MOUSE
NC score	0.116635 (rank : 840)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	457	Target Neighborhood Hits	771	Shared Neighborhood Hits	136
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

RNF8_HUMAN
NC score	0.116555 (rank : 841)	θ value	θ > 10 (rank : 1271)
Query Neighborhood Hits	457	Target Neighborhood Hits	622	Shared Neighborhood Hits	121
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

STX4_MOUSE
NC score	0.116296 (rank : 842)	θ value	θ > 10 (rank : 1408)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	116
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

MAT1_HUMAN
NC score	0.116268 (rank : 843)	θ value	0.0736092 (rank : 210)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	59
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

WDR67_MOUSE
NC score	0.116005 (rank : 844)	θ value	θ > 10 (rank : 1540)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	126
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

SHAN1_HUMAN
NC score	0.115888 (rank : 845)	θ value	0.813845 (rank : 319)
Query Neighborhood Hits	457	Target Neighborhood Hits	1041	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

U2AFM_MOUSE
NC score	0.115809 (rank : 846)	θ value	θ > 10 (rank : 1523)
Query Neighborhood Hits	457	Target Neighborhood Hits	543	Shared Neighborhood Hits	143
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

GO45_HUMAN
NC score	0.115653 (rank : 847)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	457	Target Neighborhood Hits	189	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H2G9, O15298, Q5T531, Q9GZX4	Gene names	BLZF1, JEM1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor).

SNPH_HUMAN
NC score	0.115412 (rank : 848)	θ value	θ > 10 (rank : 1354)
Query Neighborhood Hits	457	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

MCF2L_MOUSE
NC score	0.115269 (rank : 849)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

HCK_HUMAN
NC score	0.115145 (rank : 850)	θ value	0.0563607 (rank : 200)
Query Neighborhood Hits	457	Target Neighborhood Hits	1035	Shared Neighborhood Hits	159
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

LAMC1_HUMAN
NC score	0.115054 (rank : 851)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	457	Target Neighborhood Hits	922	Shared Neighborhood Hits	163
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

M3K11_HUMAN
NC score	0.114911 (rank : 852)	θ value	0.0961366 (rank : 223)
Query Neighborhood Hits	457	Target Neighborhood Hits	1136	Shared Neighborhood Hits	176
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

TCGAP_MOUSE
NC score	0.114751 (rank : 853)	θ value	θ > 10 (rank : 1447)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	114
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

M3K9_HUMAN
NC score	0.114731 (rank : 854)	θ value	0.125558 (rank : 238)
Query Neighborhood Hits	457	Target Neighborhood Hits	1123	Shared Neighborhood Hits	189
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

GBP4_HUMAN
NC score	0.114704 (rank : 855)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	457	Target Neighborhood Hits	484	Shared Neighborhood Hits	129
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

SPTN5_HUMAN
NC score	0.114617 (rank : 856)	θ value	θ > 10 (rank : 1372)
Query Neighborhood Hits	457	Target Neighborhood Hits	674	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

BFSP2_MOUSE
NC score	0.114605 (rank : 857)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	457	Target Neighborhood Hits	423	Shared Neighborhood Hits	140
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

COVA1_MOUSE
NC score	0.114162 (rank : 858)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SAFB2_HUMAN
NC score	0.113965 (rank : 859)	θ value	θ > 10 (rank : 1290)
Query Neighborhood Hits	457	Target Neighborhood Hits	720	Shared Neighborhood Hits	143
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

RBP1_MOUSE
NC score	0.113532 (rank : 860)	θ value	θ > 10 (rank : 1257)
Query Neighborhood Hits	457	Target Neighborhood Hits	493	Shared Neighborhood Hits	148
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

AKAP6_HUMAN
NC score	0.113391 (rank : 861)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	71
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

U2AFM_HUMAN
NC score	0.112582 (rank : 862)	θ value	θ > 10 (rank : 1522)
Query Neighborhood Hits	457	Target Neighborhood Hits	577	Shared Neighborhood Hits	150
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

TTC14_HUMAN
NC score	0.112471 (rank : 863)	θ value	θ > 10 (rank : 1507)
Query Neighborhood Hits	457	Target Neighborhood Hits	274	Shared Neighborhood Hits	87
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

STMN4_HUMAN
NC score	0.112004 (rank : 864)	θ value	θ > 10 (rank : 1394)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	134
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.111977 (rank : 865)	θ value	θ > 10 (rank : 1395)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	134
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

BIN3_MOUSE
NC score	0.111929 (rank : 866)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	457	Target Neighborhood Hits	165	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

TMCO3_HUMAN
NC score	0.111867 (rank : 867)	θ value	θ > 10 (rank : 1474)
Query Neighborhood Hits	457	Target Neighborhood Hits	238	Shared Neighborhood Hits	102
SwissProt Accessions	Q6UWJ1, Q5JSB1, Q6NUN1, Q8NG29, Q8TCI6, Q96EA6, Q9NWT2	Gene names	TMCO3, C13orf11
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor (Putative LAG1-interacting protein).

M3K10_HUMAN
NC score	0.111808 (rank : 868)	θ value	0.0431538 (rank : 196)
Query Neighborhood Hits	457	Target Neighborhood Hits	1071	Shared Neighborhood Hits	179
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

CLUA1_HUMAN
NC score	0.111745 (rank : 869)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	457	Target Neighborhood Hits	236	Shared Neighborhood Hits	84
SwissProt Accessions	Q96AJ1, O75138, Q65ZA3, Q9H8R4, Q9H8T1	Gene names	CLUAP1, KIAA0643
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

F107B_MOUSE
NC score	0.111725 (rank : 870)	θ value	0.813845 (rank : 308)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

F107B_HUMAN
NC score	0.111719 (rank : 871)	θ value	0.813845 (rank : 307)
Query Neighborhood Hits	457	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

DZIP3_MOUSE
NC score	0.111596 (rank : 872)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	119
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

NFL_HUMAN
NC score	0.111464 (rank : 873)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	457	Target Neighborhood Hits	666	Shared Neighborhood Hits	167
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

GCP60_HUMAN
NC score	0.111084 (rank : 874)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	457	Target Neighborhood Hits	419	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

NFL_MOUSE
NC score	0.110749 (rank : 875)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	457	Target Neighborhood Hits	695	Shared Neighborhood Hits	166
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

CROP_HUMAN
NC score	0.110682 (rank : 876)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	457	Target Neighborhood Hits	402	Shared Neighborhood Hits	112
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

PLVAP_MOUSE
NC score	0.110514 (rank : 877)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	457	Target Neighborhood Hits	210	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VC4, Q99JB1	Gene names	Plvap, Pv1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (MECA-32 antigen).

U2AFL_HUMAN
NC score	0.110251 (rank : 878)	θ value	θ > 10 (rank : 1520)
Query Neighborhood Hits	457	Target Neighborhood Hits	503	Shared Neighborhood Hits	142
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

K1HA_HUMAN
NC score	0.110161 (rank : 879)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	457	Target Neighborhood Hits	502	Shared Neighborhood Hits	153
SwissProt Accessions	O76009	Gene names	KRTHA3A, HHA3-I, HKA3A
Domain Architecture
Description	Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I).

STK10_HUMAN
NC score	0.110055 (rank : 880)	θ value	θ > 10 (rank : 1387)
Query Neighborhood Hits	457	Target Neighborhood Hits	1921	Shared Neighborhood Hits	254
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TS101_MOUSE
NC score	0.109865 (rank : 881)	θ value	θ > 10 (rank : 1504)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	108
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

PHLB1_MOUSE
NC score	0.109696 (rank : 882)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	457	Target Neighborhood Hits	678	Shared Neighborhood Hits	129
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

NFH_HUMAN
NC score	0.109527 (rank : 883)	θ value	0.279714 (rank : 266)
Query Neighborhood Hits	457	Target Neighborhood Hits	1242	Shared Neighborhood Hits	199
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DZIP3_HUMAN
NC score	0.109372 (rank : 884)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	457	Target Neighborhood Hits	399	Shared Neighborhood Hits	110
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

SDS3_HUMAN
NC score	0.109356 (rank : 885)	θ value	θ > 10 (rank : 1303)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

STMN3_HUMAN
NC score	0.109020 (rank : 886)	θ value	θ > 10 (rank : 1392)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NZ72, O75527, Q969Y4	Gene names	STMN3, SCLIP
Domain Architecture
Description	Stathmin-3 (SCG10-like protein).

KIF3C_HUMAN
NC score	0.108683 (rank : 887)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	457	Target Neighborhood Hits	478	Shared Neighborhood Hits	141
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

CT116_HUMAN
NC score	0.108569 (rank : 888)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	457	Target Neighborhood Hits	294	Shared Neighborhood Hits	88
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

BTK_HUMAN
NC score	0.108561 (rank : 889)	θ value	4.03905 (rank : 390)
Query Neighborhood Hits	457	Target Neighborhood Hits	1026	Shared Neighborhood Hits	163
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BAZ2B_HUMAN
NC score	0.108547 (rank : 890)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	457	Target Neighborhood Hits	803	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CCAR1_MOUSE
NC score	0.108330 (rank : 891)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	457	Target Neighborhood Hits	414	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

KIF3C_MOUSE
NC score	0.108301 (rank : 892)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	457	Target Neighborhood Hits	468	Shared Neighborhood Hits	139
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

ABTAP_HUMAN
NC score	0.108132 (rank : 893)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CROP_MOUSE
NC score	0.108081 (rank : 894)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	457	Target Neighborhood Hits	403	Shared Neighborhood Hits	110
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

TAOK1_HUMAN
NC score	0.108003 (rank : 895)	θ value	θ > 10 (rank : 1436)
Query Neighborhood Hits	457	Target Neighborhood Hits	1734	Shared Neighborhood Hits	252
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

CM007_HUMAN
NC score	0.107712 (rank : 896)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	457	Target Neighborhood Hits	422	Shared Neighborhood Hits	107
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

STX12_MOUSE
NC score	0.107564 (rank : 897)	θ value	θ > 10 (rank : 1397)
Query Neighborhood Hits	457	Target Neighborhood Hits	283	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

MINT_HUMAN
NC score	0.107487 (rank : 898)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	457	Target Neighborhood Hits	1291	Shared Neighborhood Hits	158
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TAOK1_MOUSE
NC score	0.107431 (rank : 899)	θ value	θ > 10 (rank : 1437)
Query Neighborhood Hits	457	Target Neighborhood Hits	1720	Shared Neighborhood Hits	251
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

RBBP6_MOUSE
NC score	0.107218 (rank : 900)	θ value	1.06291 (rank : 326)
Query Neighborhood Hits	457	Target Neighborhood Hits	1014	Shared Neighborhood Hits	117
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

K0831_HUMAN
NC score	0.106812 (rank : 901)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	457	Target Neighborhood Hits	203	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

PAWR_HUMAN
NC score	0.106713 (rank : 902)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	457	Target Neighborhood Hits	252	Shared Neighborhood Hits	82
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

TBCD2_HUMAN
NC score	0.106705 (rank : 903)	θ value	θ > 10 (rank : 1443)
Query Neighborhood Hits	457	Target Neighborhood Hits	419	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

ANR35_HUMAN
NC score	0.106691 (rank : 904)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	457	Target Neighborhood Hits	784	Shared Neighborhood Hits	150
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

K1C17_HUMAN
NC score	0.106533 (rank : 905)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	457	Target Neighborhood Hits	463	Shared Neighborhood Hits	150
SwissProt Accessions	Q04695	Gene names	KRT17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1).

EPS8_MOUSE
NC score	0.106400 (rank : 906)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	106
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

AAT1_HUMAN
NC score	0.106054 (rank : 907)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

FUT8_MOUSE
NC score	0.105815 (rank : 908)	θ value	5.27518 (rank : 404)
Query Neighborhood Hits	457	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

FRK_HUMAN
NC score	0.105715 (rank : 909)	θ value	0.0736092 (rank : 209)
Query Neighborhood Hits	457	Target Neighborhood Hits	1058	Shared Neighborhood Hits	160
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

SGOL2_HUMAN
NC score	0.105483 (rank : 910)	θ value	θ > 10 (rank : 1312)
Query Neighborhood Hits	457	Target Neighborhood Hits	207	Shared Neighborhood Hits	71
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

K2C6B_HUMAN
NC score	0.105472 (rank : 911)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	160
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C4_MOUSE
NC score	0.105463 (rank : 912)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	457	Target Neighborhood Hits	521	Shared Neighborhood Hits	165
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

ACINU_MOUSE
NC score	0.105352 (rank : 913)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	457	Target Neighborhood Hits	712	Shared Neighborhood Hits	145
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SDS3_MOUSE
NC score	0.105086 (rank : 914)	θ value	θ > 10 (rank : 1304)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

K1C9_HUMAN
NC score	0.104904 (rank : 915)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	158
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

K1C14_MOUSE
NC score	0.104753 (rank : 916)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	457	Target Neighborhood Hits	501	Shared Neighborhood Hits	156
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

CENPQ_MOUSE
NC score	0.104727 (rank : 917)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	457	Target Neighborhood Hits	160	Shared Neighborhood Hits	71
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

K2C6E_HUMAN
NC score	0.104591 (rank : 918)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	457	Target Neighborhood Hits	516	Shared Neighborhood Hits	157
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

SPTN4_HUMAN
NC score	0.104531 (rank : 919)	θ value	θ > 10 (rank : 1371)
Query Neighborhood Hits	457	Target Neighborhood Hits	570	Shared Neighborhood Hits	138
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

DAPP1_MOUSE
NC score	0.104343 (rank : 920)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

NUCB2_HUMAN
NC score	0.104234 (rank : 921)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	100
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

PKHA5_HUMAN
NC score	0.104152 (rank : 922)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	457	Target Neighborhood Hits	455	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CF010_HUMAN
NC score	0.104110 (rank : 923)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	457	Target Neighborhood Hits	329	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

FBX41_MOUSE
NC score	0.103962 (rank : 924)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	457	Target Neighborhood Hits	430	Shared Neighborhood Hits	110
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

K2C5_HUMAN
NC score	0.103953 (rank : 925)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	159
SwissProt Accessions	P13647, Q6PI71, Q6UBJ0, Q8TA91	Gene names	KRT5
Domain Architecture
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin).

SFR12_MOUSE
NC score	0.103926 (rank : 926)	θ value	1.81305 (rank : 353)
Query Neighborhood Hits	457	Target Neighborhood Hits	486	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

AKA12_HUMAN
NC score	0.103919 (rank : 927)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	457	Target Neighborhood Hits	825	Shared Neighborhood Hits	127
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

SYGP1_HUMAN
NC score	0.103815 (rank : 928)	θ value	θ > 10 (rank : 1419)
Query Neighborhood Hits	457	Target Neighborhood Hits	589	Shared Neighborhood Hits	152
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

TMCC1_HUMAN
NC score	0.103721 (rank : 929)	θ value	θ > 10 (rank : 1470)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	118
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

K1H4_HUMAN
NC score	0.103568 (rank : 930)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	149
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

STX1C_HUMAN
NC score	0.103326 (rank : 931)	θ value	θ > 10 (rank : 1402)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	115
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
NC score	0.103326 (rank : 932)	θ value	θ > 10 (rank : 1403)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	115
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

LYN_MOUSE
NC score	0.103285 (rank : 933)	θ value	1.81305 (rank : 346)
Query Neighborhood Hits	457	Target Neighborhood Hits	1023	Shared Neighborhood Hits	146
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

RILP_MOUSE
NC score	0.103234 (rank : 934)	θ value	θ > 10 (rank : 1267)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	89
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

K1H2_HUMAN
NC score	0.103197 (rank : 935)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	457	Target Neighborhood Hits	492	Shared Neighborhood Hits	147
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

K22E_HUMAN
NC score	0.103099 (rank : 936)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	457	Target Neighborhood Hits	515	Shared Neighborhood Hits	151
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

BTK_MOUSE
NC score	0.103009 (rank : 937)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	457	Target Neighborhood Hits	1017	Shared Neighborhood Hits	157
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

K1C17_MOUSE
NC score	0.102965 (rank : 938)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	457	Target Neighborhood Hits	456	Shared Neighborhood Hits	144
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

TXD11_HUMAN
NC score	0.102909 (rank : 939)	θ value	θ > 10 (rank : 1511)
Query Neighborhood Hits	457	Target Neighborhood Hits	402	Shared Neighborhood Hits	104
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TEKT2_MOUSE
NC score	0.102849 (rank : 940)	θ value	θ > 10 (rank : 1455)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q922G7, Q9WVR0	Gene names	Tekt2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t).

CCNB3_HUMAN
NC score	0.102817 (rank : 941)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	457	Target Neighborhood Hits	368	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

K1C10_HUMAN
NC score	0.102718 (rank : 942)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	457	Target Neighborhood Hits	526	Shared Neighborhood Hits	156
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

NGAP_HUMAN
NC score	0.102695 (rank : 943)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	457	Target Neighborhood Hits	517	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

DAPP1_HUMAN
NC score	0.102532 (rank : 944)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

TMCO3_MOUSE
NC score	0.102323 (rank : 945)	θ value	θ > 10 (rank : 1475)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BH01, Q3UFX1, Q7TMT5, Q8BGL4, Q8R303	Gene names	Tmco3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domain-containing protein 3 precursor.

LYN_HUMAN
NC score	0.102298 (rank : 946)	θ value	5.27518 (rank : 408)
Query Neighborhood Hits	457	Target Neighborhood Hits	1022	Shared Neighborhood Hits	144
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

K1C18_HUMAN
NC score	0.102276 (rank : 947)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	457	Target Neighborhood Hits	441	Shared Neighborhood Hits	146
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

RSF1_HUMAN
NC score	0.102252 (rank : 948)	θ value	1.81305 (rank : 352)
Query Neighborhood Hits	457	Target Neighborhood Hits	539	Shared Neighborhood Hits	105
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

K2C6C_HUMAN
NC score	0.102149 (rank : 949)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	457	Target Neighborhood Hits	503	Shared Neighborhood Hits	157
SwissProt Accessions	P48666	Gene names	KRT6C
Domain Architecture
Description	Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin).

KLC1_HUMAN
NC score	0.102093 (rank : 950)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	457	Target Neighborhood Hits	471	Shared Neighborhood Hits	149
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

A16L1_MOUSE
NC score	0.101970 (rank : 951)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	457	Target Neighborhood Hits	776	Shared Neighborhood Hits	155
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

GCP60_MOUSE
NC score	0.101967 (rank : 952)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

EPS8_HUMAN
NC score	0.101904 (rank : 953)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	91
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

K2C6A_HUMAN
NC score	0.101872 (rank : 954)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	457	Target Neighborhood Hits	505	Shared Neighborhood Hits	157
SwissProt Accessions	P02538, Q6NT67, Q96CL4	Gene names	KRT6A, K6A
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin).

RNF8_MOUSE
NC score	0.101613 (rank : 955)	θ value	θ > 10 (rank : 1272)
Query Neighborhood Hits	457	Target Neighborhood Hits	618	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TCGAP_HUMAN
NC score	0.101582 (rank : 956)	θ value	θ > 10 (rank : 1446)
Query Neighborhood Hits	457	Target Neighborhood Hits	872	Shared Neighborhood Hits	121
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SYCP2_HUMAN
NC score	0.101251 (rank : 957)	θ value	θ > 10 (rank : 1416)
Query Neighborhood Hits	457	Target Neighborhood Hits	230	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

K2C5_MOUSE
NC score	0.100807 (rank : 958)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	457	Target Neighborhood Hits	505	Shared Neighborhood Hits	162
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

RAB3I_HUMAN
NC score	0.100597 (rank : 959)	θ value	θ > 10 (rank : 1246)
Query Neighborhood Hits	457	Target Neighborhood Hits	270	Shared Neighborhood Hits	101
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

POT15_HUMAN
NC score	0.100149 (rank : 960)	θ value	θ > 10 (rank : 1233)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	187
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

XL3B_MOUSE
NC score	0.099978 (rank : 961)	θ value	θ > 10 (rank : 1548)
Query Neighborhood Hits	457	Target Neighborhood Hits	146	Shared Neighborhood Hits	74
SwissProt Accessions	Q61806, Q61244	Gene names	Xlr3b
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A (XLR-related protein A12).

NUP88_MOUSE
NC score	0.099738 (rank : 962)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	457	Target Neighborhood Hits	239	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

KI20A_HUMAN
NC score	0.099653 (rank : 963)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	101
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

FBX41_HUMAN
NC score	0.099627 (rank : 964)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	457	Target Neighborhood Hits	475	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

OTU6B_MOUSE
NC score	0.099572 (rank : 965)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

TJAP1_MOUSE
NC score	0.099539 (rank : 966)	θ value	θ > 10 (rank : 1468)
Query Neighborhood Hits	457	Target Neighborhood Hits	295	Shared Neighborhood Hits	102
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

ES8L1_HUMAN
NC score	0.099459 (rank : 967)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	457	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

EMIL2_MOUSE
NC score	0.099404 (rank : 968)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	457	Target Neighborhood Hits	485	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

DESM_MOUSE
NC score	0.099368 (rank : 969)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	457	Target Neighborhood Hits	498	Shared Neighborhood Hits	144
SwissProt Accessions	P31001	Gene names	Des
Domain Architecture
Description	Desmin.

LAMA4_MOUSE
NC score	0.099242 (rank : 970)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	457	Target Neighborhood Hits	584	Shared Neighborhood Hits	129
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

CN044_HUMAN
NC score	0.099011 (rank : 971)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

REN3A_HUMAN
NC score	0.098970 (rank : 972)	θ value	1.38821 (rank : 335)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

K1C14_HUMAN
NC score	0.098935 (rank : 973)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	457	Target Neighborhood Hits	491	Shared Neighborhood Hits	157
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

TAF3_HUMAN
NC score	0.098919 (rank : 974)	θ value	0.0961366 (rank : 229)
Query Neighborhood Hits	457	Target Neighborhood Hits	568	Shared Neighborhood Hits	103
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CCDC5_HUMAN
NC score	0.098855 (rank : 975)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	457	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

CF118_HUMAN
NC score	0.098604 (rank : 976)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	457	Target Neighborhood Hits	154	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T5N4, Q8TC11	Gene names	C6orf118
Domain Architecture	No domain graphic available
Description	Protein C6orf118.

ANR21_HUMAN
NC score	0.098571 (rank : 977)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	457	Target Neighborhood Hits	864	Shared Neighborhood Hits	183
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

APOA1_MOUSE
NC score	0.098560 (rank : 978)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	457	Target Neighborhood Hits	210	Shared Neighborhood Hits	82
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

TXND2_MOUSE
NC score	0.098556 (rank : 979)	θ value	θ > 10 (rank : 1519)
Query Neighborhood Hits	457	Target Neighborhood Hits	828	Shared Neighborhood Hits	131
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

K2C1B_MOUSE
NC score	0.098439 (rank : 980)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	457	Target Neighborhood Hits	503	Shared Neighborhood Hits	159
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

SPTN2_HUMAN
NC score	0.098297 (rank : 981)	θ value	θ > 10 (rank : 1370)
Query Neighborhood Hits	457	Target Neighborhood Hits	535	Shared Neighborhood Hits	137
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

K2C6B_MOUSE
NC score	0.098222 (rank : 982)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

LAMC2_HUMAN
NC score	0.098103 (rank : 983)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	457	Target Neighborhood Hits	715	Shared Neighborhood Hits	137
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

BLK_HUMAN
NC score	0.097872 (rank : 984)	θ value	0.62314 (rank : 296)
Query Neighborhood Hits	457	Target Neighborhood Hits	994	Shared Neighborhood Hits	137
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

K2C1_MOUSE
NC score	0.097799 (rank : 985)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	457	Target Neighborhood Hits	477	Shared Neighborhood Hits	152
SwissProt Accessions	P04104	Gene names	Krt1, Krt2-1
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin).

BAP31_HUMAN
NC score	0.097740 (rank : 986)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	89
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

STX4_HUMAN
NC score	0.097726 (rank : 987)	θ value	θ > 10 (rank : 1407)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	103
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

SYCP3_HUMAN
NC score	0.097456 (rank : 988)	θ value	θ > 10 (rank : 1417)
Query Neighborhood Hits	457	Target Neighborhood Hits	276	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

MYOC_HUMAN
NC score	0.097260 (rank : 989)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	457	Target Neighborhood Hits	489	Shared Neighborhood Hits	140
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

PERI_HUMAN
NC score	0.097254 (rank : 990)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	457	Target Neighborhood Hits	506	Shared Neighborhood Hits	147
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

PERI_MOUSE
NC score	0.097244 (rank : 991)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	457	Target Neighborhood Hits	502	Shared Neighborhood Hits	145
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

TIM44_MOUSE
NC score	0.096847 (rank : 992)	θ value	θ > 10 (rank : 1466)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	100
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

NBN_HUMAN
NC score	0.096821 (rank : 993)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	457	Target Neighborhood Hits	226	Shared Neighborhood Hits	73
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

DTBP1_HUMAN
NC score	0.096793 (rank : 994)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	457	Target Neighborhood Hits	185	Shared Neighborhood Hits	70
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

MYO3A_HUMAN
NC score	0.096636 (rank : 995)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	457	Target Neighborhood Hits	1033	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

CSK_MOUSE
NC score	0.096520 (rank : 996)	θ value	0.163984 (rank : 242)
Query Neighborhood Hits	457	Target Neighborhood Hits	1009	Shared Neighborhood Hits	130
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

DESM_HUMAN
NC score	0.096419 (rank : 997)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	457	Target Neighborhood Hits	495	Shared Neighborhood Hits	138
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

K2C6A_MOUSE
NC score	0.096342 (rank : 998)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	457	Target Neighborhood Hits	481	Shared Neighborhood Hits	152
SwissProt Accessions	P50446, Q9Z332	Gene names	Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin) (Keratin-6 alpha) (mK6-alpha).

CSK_HUMAN
NC score	0.096304 (rank : 999)	θ value	0.163984 (rank : 241)
Query Neighborhood Hits	457	Target Neighborhood Hits	1009	Shared Neighborhood Hits	130
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CEP72_HUMAN
NC score	0.096266 (rank : 1000)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	457	Target Neighborhood Hits	374	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

SLK_HUMAN
NC score	0.096143 (rank : 1001)	θ value	0.00390308 (rank : 134)
Query Neighborhood Hits	457	Target Neighborhood Hits	1775	Shared Neighborhood Hits	244
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

K1H2_MOUSE
NC score	0.096085 (rank : 1002)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	457	Target Neighborhood Hits	446	Shared Neighborhood Hits	144
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

TMCC1_MOUSE
NC score	0.095851 (rank : 1003)	θ value	θ > 10 (rank : 1471)
Query Neighborhood Hits	457	Target Neighborhood Hits	315	Shared Neighborhood Hits	117
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

LRRF1_MOUSE
NC score	0.095834 (rank : 1004)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	457	Target Neighborhood Hits	440	Shared Neighborhood Hits	106
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

TAOK3_HUMAN
NC score	0.095811 (rank : 1005)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	457	Target Neighborhood Hits	1494	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

CCD37_HUMAN
NC score	0.095701 (rank : 1006)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	92
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

PRP40_HUMAN
NC score	0.095652 (rank : 1007)	θ value	θ > 10 (rank : 1240)
Query Neighborhood Hits	457	Target Neighborhood Hits	442	Shared Neighborhood Hits	115
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

LAMC1_MOUSE
NC score	0.094980 (rank : 1008)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	457	Target Neighborhood Hits	856	Shared Neighborhood Hits	159
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

GPS2_HUMAN
NC score	0.094971 (rank : 1009)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	457	Target Neighborhood Hits	459	Shared Neighborhood Hits	95
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

K1C16_MOUSE
NC score	0.094829 (rank : 1010)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	457	Target Neighborhood Hits	444	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Z2K1	Gene names	Krt16, Krt1-16
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

CCD50_HUMAN
NC score	0.094750 (rank : 1011)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	457	Target Neighborhood Hits	237	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

MICA1_MOUSE
NC score	0.094556 (rank : 1012)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	457	Target Neighborhood Hits	400	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

TEX14_MOUSE
NC score	0.094536 (rank : 1013)	θ value	θ > 10 (rank : 1459)
Query Neighborhood Hits	457	Target Neighborhood Hits	1333	Shared Neighborhood Hits	179
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR11_HUMAN
NC score	0.094454 (rank : 1014)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	457	Target Neighborhood Hits	1289	Shared Neighborhood Hits	184
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PHF20_MOUSE
NC score	0.094338 (rank : 1015)	θ value	0.0961366 (rank : 227)
Query Neighborhood Hits	457	Target Neighborhood Hits	513	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

K2C4_HUMAN
NC score	0.094201 (rank : 1016)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	457	Target Neighborhood Hits	471	Shared Neighborhood Hits	155
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

BLK_MOUSE
NC score	0.094188 (rank : 1017)	θ value	3.0926 (rank : 375)
Query Neighborhood Hits	457	Target Neighborhood Hits	992	Shared Neighborhood Hits	125
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

NUCB1_HUMAN
NC score	0.094175 (rank : 1018)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	102
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

STMN3_MOUSE
NC score	0.093803 (rank : 1019)	θ value	θ > 10 (rank : 1393)
Query Neighborhood Hits	457	Target Neighborhood Hits	331	Shared Neighborhood Hits	113
SwissProt Accessions	O70166	Gene names	Stmn3, Sclip
Domain Architecture
Description	Stathmin-3 (SCG10-like protein) (SCG10-related protein HiAT3) (Hippocampus abundant transcript 3).

K2C1B_HUMAN
NC score	0.093647 (rank : 1020)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	457	Target Neighborhood Hits	542	Shared Neighborhood Hits	161
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

MAT1_MOUSE
NC score	0.093478 (rank : 1021)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	69
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

SH21B_MOUSE
NC score	0.093344 (rank : 1022)	θ value	θ > 10 (rank : 1316)
Query Neighborhood Hits	457	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

ACINU_HUMAN
NC score	0.092943 (rank : 1023)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	457	Target Neighborhood Hits	828	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TRAF3_HUMAN
NC score	0.092852 (rank : 1024)	θ value	θ > 10 (rank : 1491)
Query Neighborhood Hits	457	Target Neighborhood Hits	463	Shared Neighborhood Hits	124
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

DMN_HUMAN
NC score	0.092796 (rank : 1025)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	457	Target Neighborhood Hits	690	Shared Neighborhood Hits	158
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

K1C20_HUMAN
NC score	0.092650 (rank : 1026)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	457	Target Neighborhood Hits	468	Shared Neighborhood Hits	144
SwissProt Accessions	P35900	Gene names	KRT20
Domain Architecture
Description	Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT).

BAZ1B_HUMAN
NC score	0.092309 (rank : 1027)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	457	Target Neighborhood Hits	701	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

MCF2_HUMAN
NC score	0.092064 (rank : 1028)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	457	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

TRAF3_MOUSE
NC score	0.092042 (rank : 1029)	θ value	θ > 10 (rank : 1492)
Query Neighborhood Hits	457	Target Neighborhood Hits	476	Shared Neighborhood Hits	125
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

CCD55_HUMAN
NC score	0.092033 (rank : 1030)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	457	Target Neighborhood Hits	513	Shared Neighborhood Hits	113
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

K2C6G_MOUSE
NC score	0.091928 (rank : 1031)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	457	Target Neighborhood Hits	452	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

OTU6B_HUMAN
NC score	0.091765 (rank : 1032)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	457	Target Neighborhood Hits	182	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N6M0, Q9NTA4, Q9Y387	Gene names	OTUD6B
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

STK31_MOUSE
NC score	0.091753 (rank : 1033)	θ value	3.0926 (rank : 386)
Query Neighborhood Hits	457	Target Neighborhood Hits	474	Shared Neighborhood Hits	91
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

K1C15_MOUSE
NC score	0.091654 (rank : 1034)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	457	Target Neighborhood Hits	429	Shared Neighborhood Hits	138
SwissProt Accessions	Q61414, Q6PEQ0	Gene names	Krt15, Krt1-15
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

K1H1_MOUSE
NC score	0.091643 (rank : 1035)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	457	Target Neighborhood Hits	450	Shared Neighborhood Hits	140
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

CENPK_MOUSE
NC score	0.091570 (rank : 1036)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	457	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

LAMA3_MOUSE
NC score	0.091557 (rank : 1037)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	457	Target Neighborhood Hits	859	Shared Neighborhood Hits	146
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMB1_MOUSE
NC score	0.091300 (rank : 1038)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	457	Target Neighborhood Hits	919	Shared Neighborhood Hits	158
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRC27_HUMAN
NC score	0.091167 (rank : 1039)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	457	Target Neighborhood Hits	710	Shared Neighborhood Hits	127
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

ES8L1_MOUSE
NC score	0.091146 (rank : 1040)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	457	Target Neighborhood Hits	143	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

K1C16_HUMAN
NC score	0.090989 (rank : 1041)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	457	Target Neighborhood Hits	440	Shared Neighborhood Hits	139
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

XL3A_MOUSE
NC score	0.090514 (rank : 1042)	θ value	θ > 10 (rank : 1547)
Query Neighborhood Hits	457	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

K1HB_HUMAN
NC score	0.090265 (rank : 1043)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	457	Target Neighborhood Hits	470	Shared Neighborhood Hits	142
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

K1C10_MOUSE
NC score	0.090140 (rank : 1044)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	457	Target Neighborhood Hits	466	Shared Neighborhood Hits	141
SwissProt Accessions	P02535, P08731, Q8BUX3, Q8BV09, Q8BVU3, Q9CXH6, Q9JKB4	Gene names	Krt10, Krt1-10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) (56 kDa cytokeratin) (Keratin, type I cytoskeletal 59 kDa).

STK31_HUMAN
NC score	0.090105 (rank : 1045)	θ value	θ > 10 (rank : 1388)
Query Neighborhood Hits	457	Target Neighborhood Hits	570	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

MRCKG_MOUSE
NC score	0.090039 (rank : 1046)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	457	Target Neighborhood Hits	1466	Shared Neighborhood Hits	213
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

FER_HUMAN
NC score	0.089968 (rank : 1047)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	457	Target Neighborhood Hits	1278	Shared Neighborhood Hits	211
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

RHG25_HUMAN
NC score	0.089894 (rank : 1048)	θ value	θ > 10 (rank : 1263)
Query Neighborhood Hits	457	Target Neighborhood Hits	550	Shared Neighborhood Hits	139
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PTK6_MOUSE
NC score	0.089812 (rank : 1049)	θ value	5.27518 (rank : 413)
Query Neighborhood Hits	457	Target Neighborhood Hits	1026	Shared Neighborhood Hits	142
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

ATRX_MOUSE
NC score	0.089804 (rank : 1050)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	457	Target Neighborhood Hits	682	Shared Neighborhood Hits	135
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

PKHG1_HUMAN
NC score	0.089593 (rank : 1051)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	457	Target Neighborhood Hits	174	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

KI20A_MOUSE
NC score	0.089561 (rank : 1052)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	457	Target Neighborhood Hits	310	Shared Neighborhood Hits	95
SwissProt Accessions	P97329, Q542M4	Gene names	Kif20a, Rab6kifl
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (Kinesin-like protein 174).

PLCB3_MOUSE
NC score	0.089414 (rank : 1053)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	114
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

NIPBL_HUMAN
NC score	0.089279 (rank : 1054)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	457	Target Neighborhood Hits	1311	Shared Neighborhood Hits	168
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DTBP1_MOUSE
NC score	0.089182 (rank : 1055)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	457	Target Neighborhood Hits	209	Shared Neighborhood Hits	71
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

SAFB2_MOUSE
NC score	0.089059 (rank : 1056)	θ value	θ > 10 (rank : 1291)
Query Neighborhood Hits	457	Target Neighborhood Hits	581	Shared Neighborhood Hits	125
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

A16L1_HUMAN
NC score	0.088813 (rank : 1057)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	457	Target Neighborhood Hits	664	Shared Neighborhood Hits	132
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

TAF3_MOUSE
NC score	0.088784 (rank : 1058)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	457	Target Neighborhood Hits	463	Shared Neighborhood Hits	98
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

LMO7_HUMAN
NC score	0.088749 (rank : 1059)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	457	Target Neighborhood Hits	507	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

TAOK3_MOUSE
NC score	0.088602 (rank : 1060)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	457	Target Neighborhood Hits	1458	Shared Neighborhood Hits	216
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

ATRIP_HUMAN
NC score	0.088458 (rank : 1061)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

BFSP2_HUMAN
NC score	0.088455 (rank : 1062)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	122
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

LCK_HUMAN
NC score	0.088403 (rank : 1063)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	457	Target Neighborhood Hits	987	Shared Neighborhood Hits	118
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

DNJC8_MOUSE
NC score	0.088357 (rank : 1064)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	457	Target Neighborhood Hits	392	Shared Neighborhood Hits	96
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

FUT8_HUMAN
NC score	0.088180 (rank : 1065)	θ value	4.03905 (rank : 394)
Query Neighborhood Hits	457	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

SLK_MOUSE
NC score	0.087765 (rank : 1066)	θ value	θ > 10 (rank : 1345)
Query Neighborhood Hits	457	Target Neighborhood Hits	1798	Shared Neighborhood Hits	237
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

LCK_MOUSE
NC score	0.087748 (rank : 1067)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	457	Target Neighborhood Hits	981	Shared Neighborhood Hits	118
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

TRIO_HUMAN
NC score	0.087363 (rank : 1068)	θ value	θ > 10 (rank : 1501)
Query Neighborhood Hits	457	Target Neighborhood Hits	1580	Shared Neighborhood Hits	202
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

SLY_MOUSE
NC score	0.087350 (rank : 1069)	θ value	θ > 10 (rank : 1347)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

TXK_MOUSE
NC score	0.087309 (rank : 1070)	θ value	θ > 10 (rank : 1513)
Query Neighborhood Hits	457	Target Neighborhood Hits	980	Shared Neighborhood Hits	132
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

CENPQ_HUMAN
NC score	0.087244 (rank : 1071)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	457	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

PTK6_HUMAN
NC score	0.087195 (rank : 1072)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	457	Target Neighborhood Hits	1020	Shared Neighborhood Hits	145
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

NFH_MOUSE
NC score	0.087185 (rank : 1073)	θ value	1.38821 (rank : 332)
Query Neighborhood Hits	457	Target Neighborhood Hits	2247	Shared Neighborhood Hits	226
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EMIL3_MOUSE
NC score	0.087181 (rank : 1074)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	457	Target Neighborhood Hits	240	Shared Neighborhood Hits	86
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

PRP40_MOUSE
NC score	0.087088 (rank : 1075)	θ value	θ > 10 (rank : 1241)
Query Neighborhood Hits	457	Target Neighborhood Hits	447	Shared Neighborhood Hits	108
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PHF20_HUMAN
NC score	0.086988 (rank : 1076)	θ value	0.279714 (rank : 267)
Query Neighborhood Hits	457	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

DAAM1_MOUSE
NC score	0.086918 (rank : 1077)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	457	Target Neighborhood Hits	443	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

MYO3B_HUMAN
NC score	0.086906 (rank : 1078)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	457	Target Neighborhood Hits	923	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

OXR1_MOUSE
NC score	0.086840 (rank : 1079)	θ value	5.27518 (rank : 411)
Query Neighborhood Hits	457	Target Neighborhood Hits	516	Shared Neighborhood Hits	101
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SCG3_MOUSE
NC score	0.086469 (rank : 1080)	θ value	θ > 10 (rank : 1298)
Query Neighborhood Hits	457	Target Neighborhood Hits	170	Shared Neighborhood Hits	70
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

APOB_HUMAN
NC score	0.086171 (rank : 1081)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	64
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

APOE_HUMAN
NC score	0.086106 (rank : 1082)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	70
SwissProt Accessions	P02649, Q9P2S4	Gene names	APOE
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

K1C18_MOUSE
NC score	0.085954 (rank : 1083)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	457	Target Neighborhood Hits	386	Shared Neighborhood Hits	132
SwissProt Accessions	P05784, Q61766	Gene names	Krt18, Kerd, Krt1-18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18) (Cytokeratin endo B) (Keratin D).

CT116_MOUSE
NC score	0.085772 (rank : 1084)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	457	Target Neighborhood Hits	268	Shared Neighborhood Hits	68
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

SH21B_HUMAN
NC score	0.085741 (rank : 1085)	θ value	θ > 10 (rank : 1315)
Query Neighborhood Hits	457	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

HOME3_MOUSE
NC score	0.085677 (rank : 1086)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	457	Target Neighborhood Hits	316	Shared Neighborhood Hits	104
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

AFAD_HUMAN
NC score	0.085575 (rank : 1087)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	457	Target Neighborhood Hits	689	Shared Neighborhood Hits	135
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CCDC3_MOUSE
NC score	0.085506 (rank : 1088)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	457	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

MYO3A_MOUSE
NC score	0.085051 (rank : 1089)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	457	Target Neighborhood Hits	902	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

SHB_MOUSE
NC score	0.085028 (rank : 1090)	θ value	θ > 10 (rank : 1325)
Query Neighborhood Hits	457	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

CCD37_MOUSE
NC score	0.084890 (rank : 1091)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

TNNT1_MOUSE
NC score	0.084827 (rank : 1092)	θ value	θ > 10 (rank : 1479)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	91
SwissProt Accessions	O88346, O88795, Q9QUP7	Gene names	Tnnt1
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

SHE_MOUSE
NC score	0.084776 (rank : 1093)	θ value	θ > 10 (rank : 1335)
Query Neighborhood Hits	457	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

NUP62_HUMAN
NC score	0.084698 (rank : 1094)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	457	Target Neighborhood Hits	195	Shared Neighborhood Hits	65
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

CLSPN_HUMAN
NC score	0.084602 (rank : 1095)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	457	Target Neighborhood Hits	433	Shared Neighborhood Hits	115
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

GBP2_HUMAN
NC score	0.084473 (rank : 1096)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	457	Target Neighborhood Hits	349	Shared Neighborhood Hits	104
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

ARHG3_HUMAN
NC score	0.084350 (rank : 1097)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	457	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

TEC_HUMAN
NC score	0.084218 (rank : 1098)	θ value	θ > 10 (rank : 1450)
Query Neighborhood Hits	457	Target Neighborhood Hits	1006	Shared Neighborhood Hits	133
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

DNJC8_HUMAN
NC score	0.084127 (rank : 1099)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	457	Target Neighborhood Hits	380	Shared Neighborhood Hits	92
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

C8AP2_HUMAN
NC score	0.084050 (rank : 1100)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	457	Target Neighborhood Hits	548	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

WDR60_MOUSE
NC score	0.083993 (rank : 1101)	θ value	θ > 10 (rank : 1538)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	91
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ARHG8_MOUSE
NC score	0.083892 (rank : 1102)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	457	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

TEKT3_HUMAN
NC score	0.083678 (rank : 1103)	θ value	θ > 10 (rank : 1456)
Query Neighborhood Hits	457	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXF9, Q8N5R5, Q96M48	Gene names	TEKT3
Domain Architecture
Description	Tektin-3.

MRCKG_HUMAN
NC score	0.083660 (rank : 1104)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	457	Target Neighborhood Hits	1519	Shared Neighborhood Hits	202
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

GBP1_HUMAN
NC score	0.083430 (rank : 1105)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	457	Target Neighborhood Hits	339	Shared Neighborhood Hits	111
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

K1H1_HUMAN
NC score	0.083422 (rank : 1106)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	457	Target Neighborhood Hits	433	Shared Neighborhood Hits	128
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

ANGP2_HUMAN
NC score	0.083397 (rank : 1107)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	457	Target Neighborhood Hits	400	Shared Neighborhood Hits	123
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

SHB_HUMAN
NC score	0.083354 (rank : 1108)	θ value	θ > 10 (rank : 1324)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC3_MOUSE
NC score	0.083294 (rank : 1109)	θ value	θ > 10 (rank : 1331)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	51
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

ARHG3_MOUSE
NC score	0.083291 (rank : 1110)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	457	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

MIPO1_MOUSE
NC score	0.083130 (rank : 1111)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	457	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D9F8	Gene names	Mipol1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein homolog.

ANGP2_MOUSE
NC score	0.083004 (rank : 1112)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	457	Target Neighborhood Hits	397	Shared Neighborhood Hits	133
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

AINX_HUMAN
NC score	0.082824 (rank : 1113)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	457	Target Neighborhood Hits	442	Shared Neighborhood Hits	135
SwissProt Accessions	Q16352, Q9BRC5	Gene names	INA
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

ATD3B_HUMAN
NC score	0.082809 (rank : 1114)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	457	Target Neighborhood Hits	340	Shared Neighborhood Hits	100
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

SHC1_MOUSE
NC score	0.082645 (rank : 1115)	θ value	θ > 10 (rank : 1327)
Query Neighborhood Hits	457	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

ABL1_MOUSE
NC score	0.082641 (rank : 1116)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	457	Target Neighborhood Hits	1178	Shared Neighborhood Hits	124
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

DAAM1_HUMAN
NC score	0.082455 (rank : 1117)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	457	Target Neighborhood Hits	483	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

GBP2_MOUSE
NC score	0.082337 (rank : 1118)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	457	Target Neighborhood Hits	323	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

SHE_HUMAN
NC score	0.082302 (rank : 1119)	θ value	θ > 10 (rank : 1334)
Query Neighborhood Hits	457	Target Neighborhood Hits	164	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

TEKT2_HUMAN
NC score	0.082194 (rank : 1120)	θ value	θ > 10 (rank : 1454)
Query Neighborhood Hits	457	Target Neighborhood Hits	197	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

TFAP4_HUMAN
NC score	0.082146 (rank : 1121)	θ value	θ > 10 (rank : 1461)
Query Neighborhood Hits	457	Target Neighborhood Hits	289	Shared Neighborhood Hits	78
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TEC_MOUSE
NC score	0.082116 (rank : 1122)	θ value	θ > 10 (rank : 1451)
Query Neighborhood Hits	457	Target Neighborhood Hits	1006	Shared Neighborhood Hits	131
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ARHGA_HUMAN
NC score	0.081959 (rank : 1123)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	457	Target Neighborhood Hits	187	Shared Neighborhood Hits	47
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ABL1_HUMAN
NC score	0.081939 (rank : 1124)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	457	Target Neighborhood Hits	1220	Shared Neighborhood Hits	130
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

K22O_HUMAN
NC score	0.081933 (rank : 1125)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	457	Target Neighborhood Hits	485	Shared Neighborhood Hits	144
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

ESCO1_HUMAN
NC score	0.081797 (rank : 1126)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	457	Target Neighborhood Hits	361	Shared Neighborhood Hits	88
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

TIAM1_MOUSE
NC score	0.081593 (rank : 1127)	θ value	θ > 10 (rank : 1464)
Query Neighborhood Hits	457	Target Neighborhood Hits	205	Shared Neighborhood Hits	30
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

NOP14_MOUSE
NC score	0.081503 (rank : 1128)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

K1H6_HUMAN
NC score	0.081486 (rank : 1129)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	457	Target Neighborhood Hits	408	Shared Neighborhood Hits	131
SwissProt Accessions	O76013	Gene names	KRTHA6, HHA6, HKA6
Domain Architecture
Description	Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6).

EMIL3_HUMAN
NC score	0.081400 (rank : 1130)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

PFD6_MOUSE
NC score	0.081088 (rank : 1131)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	457	Target Neighborhood Hits	152	Shared Neighborhood Hits	68
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

IQGA1_HUMAN
NC score	0.081048 (rank : 1132)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	457	Target Neighborhood Hits	250	Shared Neighborhood Hits	91
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

GRB14_MOUSE
NC score	0.080880 (rank : 1133)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	457	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

CM007_MOUSE
NC score	0.080592 (rank : 1134)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	457	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TIAM1_HUMAN
NC score	0.080520 (rank : 1135)	θ value	θ > 10 (rank : 1463)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

OXR1_HUMAN
NC score	0.080477 (rank : 1136)	θ value	1.06291 (rank : 325)
Query Neighborhood Hits	457	Target Neighborhood Hits	282	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

AINX_MOUSE
NC score	0.080450 (rank : 1137)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	457	Target Neighborhood Hits	448	Shared Neighborhood Hits	138
SwissProt Accessions	P46660, Q61958, Q8VCW5	Gene names	Ina
Domain Architecture
Description	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (Neurofilament-66) (NF-66).

TXK_HUMAN
NC score	0.080404 (rank : 1138)	θ value	θ > 10 (rank : 1512)
Query Neighborhood Hits	457	Target Neighborhood Hits	971	Shared Neighborhood Hits	121
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

K1C13_MOUSE
NC score	0.080157 (rank : 1139)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	457	Target Neighborhood Hits	410	Shared Neighborhood Hits	133
SwissProt Accessions	P08730, Q3V176, Q6PAI1	Gene names	Krt13, Krt1-13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13) (47 kDa cytokeratin).

STX18_HUMAN
NC score	0.080120 (rank : 1140)	θ value	θ > 10 (rank : 1398)
Query Neighborhood Hits	457	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

TJAP1_HUMAN
NC score	0.080100 (rank : 1141)	θ value	θ > 10 (rank : 1467)
Query Neighborhood Hits	457	Target Neighborhood Hits	214	Shared Neighborhood Hits	74
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

PREX1_HUMAN
NC score	0.080098 (rank : 1142)	θ value	θ > 10 (rank : 1239)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

STX12_HUMAN
NC score	0.080072 (rank : 1143)	θ value	θ > 10 (rank : 1396)
Query Neighborhood Hits	457	Target Neighborhood Hits	226	Shared Neighborhood Hits	94
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

CCD16_MOUSE
NC score	0.079890 (rank : 1144)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	457	Target Neighborhood Hits	218	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

SNP25_HUMAN
NC score	0.079851 (rank : 1145)	θ value	θ > 10 (rank : 1352)
Query Neighborhood Hits	457	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	P60880, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	SNAP25, SNAP
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNP25_MOUSE
NC score	0.079851 (rank : 1146)	θ value	θ > 10 (rank : 1353)
Query Neighborhood Hits	457	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	P60879, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	Snap25, Snap
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

PTRF_HUMAN
NC score	0.079740 (rank : 1147)	θ value	θ > 10 (rank : 1244)
Query Neighborhood Hits	457	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q6NZI2, O00535, Q6GMY1, Q96H74, Q9BT85, Q9HAP4	Gene names	PTRF
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor (PTRF protein).

SMCE1_MOUSE
NC score	0.079495 (rank : 1148)	θ value	θ > 10 (rank : 1350)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	80
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

EXOC1_HUMAN
NC score	0.079474 (rank : 1149)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	457	Target Neighborhood Hits	183	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

NOL10_HUMAN
NC score	0.079463 (rank : 1150)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

K2C3_HUMAN
NC score	0.079422 (rank : 1151)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	457	Target Neighborhood Hits	443	Shared Neighborhood Hits	132
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

ZN318_HUMAN
NC score	0.079397 (rank : 1152)	θ value	θ > 10 (rank : 1556)
Query Neighborhood Hits	457	Target Neighborhood Hits	497	Shared Neighborhood Hits	125
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

GRB14_HUMAN
NC score	0.079296 (rank : 1153)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	457	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

K1C23_MOUSE
NC score	0.079014 (rank : 1154)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	457	Target Neighborhood Hits	370	Shared Neighborhood Hits	130
SwissProt Accessions	Q99PS0	Gene names	Krt23, Haik1, Krt1-23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

SHC3_HUMAN
NC score	0.078849 (rank : 1155)	θ value	θ > 10 (rank : 1330)
Query Neighborhood Hits	457	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

APS_HUMAN
NC score	0.078774 (rank : 1156)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	457	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

KRHB6_HUMAN
NC score	0.078762 (rank : 1157)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	457	Target Neighborhood Hits	447	Shared Neighborhood Hits	130
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

KLC1_MOUSE
NC score	0.078635 (rank : 1158)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	457	Target Neighborhood Hits	357	Shared Neighborhood Hits	123
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

SHD_MOUSE
NC score	0.078610 (rank : 1159)	θ value	θ > 10 (rank : 1333)
Query Neighborhood Hits	457	Target Neighborhood Hits	137	Shared Neighborhood Hits	50
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

HOME3_HUMAN
NC score	0.078557 (rank : 1160)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	457	Target Neighborhood Hits	275	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

STX1B_HUMAN
NC score	0.078556 (rank : 1161)	θ value	θ > 10 (rank : 1401)
Query Neighborhood Hits	457	Target Neighborhood Hits	252	Shared Neighborhood Hits	99
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

SHD_HUMAN
NC score	0.078355 (rank : 1162)	θ value	θ > 10 (rank : 1332)
Query Neighborhood Hits	457	Target Neighborhood Hits	204	Shared Neighborhood Hits	49
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

CRIP1_HUMAN
NC score	0.078267 (rank : 1163)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	457	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	P50238, Q13628, Q96J34	Gene names	CRIP1, CRIP
Domain Architecture
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP) (Cysteine-rich heart protein) (hCRHP).

ABL2_HUMAN
NC score	0.078244 (rank : 1164)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	457	Target Neighborhood Hits	1045	Shared Neighborhood Hits	115
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

EXOC1_MOUSE
NC score	0.078232 (rank : 1165)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R3S6	Gene names	Exoc1, Sec3, Sec3l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

LIN1_HUMAN
NC score	0.078228 (rank : 1166)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	457	Target Neighborhood Hits	187	Shared Neighborhood Hits	74
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

ARHG8_HUMAN
NC score	0.078200 (rank : 1167)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	457	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ENAH_MOUSE
NC score	0.078146 (rank : 1168)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	457	Target Neighborhood Hits	919	Shared Neighborhood Hits	136
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CS029_HUMAN
NC score	0.078145 (rank : 1169)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	457	Target Neighborhood Hits	329	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

KRHB1_HUMAN
NC score	0.077911 (rank : 1170)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	457	Target Neighborhood Hits	461	Shared Neighborhood Hits	128
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

SHC1_HUMAN
NC score	0.077874 (rank : 1171)	θ value	θ > 10 (rank : 1326)
Query Neighborhood Hits	457	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SYCP3_MOUSE
NC score	0.077773 (rank : 1172)	θ value	θ > 10 (rank : 1418)
Query Neighborhood Hits	457	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

STX1A_HUMAN
NC score	0.077718 (rank : 1173)	θ value	θ > 10 (rank : 1399)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	105
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

CRIP1_MOUSE
NC score	0.077663 (rank : 1174)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	457	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	P63254, P04006, Q3THF0	Gene names	Crip1, Crip
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP).

ARHGA_MOUSE
NC score	0.077615 (rank : 1175)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	457	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

PPIG_HUMAN
NC score	0.077488 (rank : 1176)	θ value	θ > 10 (rank : 1234)
Query Neighborhood Hits	457	Target Neighborhood Hits	670	Shared Neighborhood Hits	142
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

DISC1_HUMAN
NC score	0.077380 (rank : 1177)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

K1C13_HUMAN
NC score	0.077161 (rank : 1178)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	457	Target Neighborhood Hits	386	Shared Neighborhood Hits	127
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

CD72_HUMAN
NC score	0.077079 (rank : 1179)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	457	Target Neighborhood Hits	345	Shared Neighborhood Hits	90
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

CHCH3_HUMAN
NC score	0.077026 (rank : 1180)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

KRHB3_HUMAN
NC score	0.076828 (rank : 1181)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	457	Target Neighborhood Hits	438	Shared Neighborhood Hits	130
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

U2AFL_MOUSE
NC score	0.076663 (rank : 1182)	θ value	θ > 10 (rank : 1521)
Query Neighborhood Hits	457	Target Neighborhood Hits	389	Shared Neighborhood Hits	102
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

SRMS_MOUSE
NC score	0.076649 (rank : 1183)	θ value	0.365318 (rank : 283)
Query Neighborhood Hits	457	Target Neighborhood Hits	964	Shared Neighborhood Hits	104
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SHC2_HUMAN
NC score	0.076430 (rank : 1184)	θ value	θ > 10 (rank : 1328)
Query Neighborhood Hits	457	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

HM20A_MOUSE
NC score	0.076338 (rank : 1185)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	457	Target Neighborhood Hits	348	Shared Neighborhood Hits	103
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

SHC2_MOUSE
NC score	0.076226 (rank : 1186)	θ value	θ > 10 (rank : 1329)
Query Neighborhood Hits	457	Target Neighborhood Hits	144	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

TRIM8_HUMAN
NC score	0.076135 (rank : 1187)	θ value	θ > 10 (rank : 1499)
Query Neighborhood Hits	457	Target Neighborhood Hits	650	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

K1C12_MOUSE
NC score	0.076106 (rank : 1188)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	457	Target Neighborhood Hits	409	Shared Neighborhood Hits	127
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

K1H7_HUMAN
NC score	0.076069 (rank : 1189)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	457	Target Neighborhood Hits	369	Shared Neighborhood Hits	127
SwissProt Accessions	O76014	Gene names	KRTHA7, HHA7, HKA7
Domain Architecture
Description	Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7).

SURF6_MOUSE
NC score	0.075949 (rank : 1190)	θ value	θ > 10 (rank : 1411)
Query Neighborhood Hits	457	Target Neighborhood Hits	195	Shared Neighborhood Hits	62
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

BSN_HUMAN
NC score	0.075841 (rank : 1191)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	457	Target Neighborhood Hits	1537	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RT26_HUMAN
NC score	0.075785 (rank : 1192)	θ value	θ > 10 (rank : 1280)
Query Neighborhood Hits	457	Target Neighborhood Hits	75	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYN8, Q96Q58	Gene names	MRPS26, RPMS13
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S26, mitochondrial precursor (MRP-S26) (MRP- S13).

ITK_HUMAN
NC score	0.075775 (rank : 1193)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	457	Target Neighborhood Hits	1016	Shared Neighborhood Hits	130
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

HSH2D_HUMAN
NC score	0.075775 (rank : 1194)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	457	Target Neighborhood Hits	159	Shared Neighborhood Hits	42
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

DAAM2_HUMAN
NC score	0.075673 (rank : 1195)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	457	Target Neighborhood Hits	350	Shared Neighborhood Hits	112
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ARHGF_HUMAN
NC score	0.075511 (rank : 1196)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	457	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

HTSF1_HUMAN
NC score	0.075260 (rank : 1197)	θ value	0.813845 (rank : 310)
Query Neighborhood Hits	457	Target Neighborhood Hits	408	Shared Neighborhood Hits	76
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

GEMI_MOUSE
NC score	0.075233 (rank : 1198)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	457	Target Neighborhood Hits	163	Shared Neighborhood Hits	58
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

UBP8_HUMAN
NC score	0.075026 (rank : 1199)	θ value	3.0926 (rank : 387)
Query Neighborhood Hits	457	Target Neighborhood Hits	751	Shared Neighborhood Hits	176
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

NUP62_MOUSE
NC score	0.074880 (rank : 1200)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	457	Target Neighborhood Hits	200	Shared Neighborhood Hits	63
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

STX1A_MOUSE
NC score	0.074838 (rank : 1201)	θ value	θ > 10 (rank : 1400)
Query Neighborhood Hits	457	Target Neighborhood Hits	261	Shared Neighborhood Hits	102
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

ITK_MOUSE
NC score	0.074759 (rank : 1202)	θ value	0.0252991 (rank : 178)
Query Neighborhood Hits	457	Target Neighborhood Hits	985	Shared Neighborhood Hits	114
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

K1H8_HUMAN
NC score	0.074665 (rank : 1203)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	457	Target Neighborhood Hits	394	Shared Neighborhood Hits	121
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

KI13B_HUMAN
NC score	0.074564 (rank : 1204)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	457	Target Neighborhood Hits	492	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

HM20A_HUMAN
NC score	0.074491 (rank : 1205)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	457	Target Neighborhood Hits	343	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

KI13A_MOUSE
NC score	0.074290 (rank : 1206)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	457	Target Neighborhood Hits	395	Shared Neighborhood Hits	121
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

K1914_HUMAN
NC score	0.074260 (rank : 1207)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K2C7_HUMAN
NC score	0.074244 (rank : 1208)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	457	Target Neighborhood Hits	369	Shared Neighborhood Hits	124
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

TTC1_HUMAN
NC score	0.074187 (rank : 1209)	θ value	θ > 10 (rank : 1508)
Query Neighborhood Hits	457	Target Neighborhood Hits	417	Shared Neighborhood Hits	104
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

K1C15_HUMAN
NC score	0.074077 (rank : 1210)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	457	Target Neighborhood Hits	367	Shared Neighborhood Hits	120
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

SLY_HUMAN
NC score	0.073883 (rank : 1211)	θ value	θ > 10 (rank : 1346)
Query Neighborhood Hits	457	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

ATRIP_MOUSE
NC score	0.073879 (rank : 1212)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

EXOC5_HUMAN
NC score	0.073621 (rank : 1213)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	457	Target Neighborhood Hits	194	Shared Neighborhood Hits	78
SwissProt Accessions	O00471	Gene names	EXOC5, SEC10, SEC10L1
Domain Architecture
Description	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10).

CCD55_MOUSE
NC score	0.073515 (rank : 1214)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	457	Target Neighborhood Hits	519	Shared Neighborhood Hits	90
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

LC7L2_MOUSE
NC score	0.073442 (rank : 1215)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	457	Target Neighborhood Hits	244	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

CCD38_MOUSE
NC score	0.073238 (rank : 1216)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	457	Target Neighborhood Hits	165	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CDN8, Q8CDD6, Q8CDE1	Gene names	Ccdc38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

ANLN_MOUSE
NC score	0.073232 (rank : 1217)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	457	Target Neighborhood Hits	297	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

LAMC2_MOUSE
NC score	0.073158 (rank : 1218)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	457	Target Neighborhood Hits	614	Shared Neighborhood Hits	108
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NTBP1_HUMAN
NC score	0.073151 (rank : 1219)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	457	Target Neighborhood Hits	171	Shared Neighborhood Hits	67
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

TRAF5_HUMAN
NC score	0.072993 (rank : 1220)	θ value	θ > 10 (rank : 1493)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	111
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

ATAD3_MOUSE
NC score	0.072937 (rank : 1221)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	457	Target Neighborhood Hits	326	Shared Neighborhood Hits	97
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CT151_HUMAN
NC score	0.072815 (rank : 1222)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	457	Target Neighborhood Hits	382	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CA049_MOUSE
NC score	0.072740 (rank : 1223)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	457	Target Neighborhood Hits	121	Shared Neighborhood Hits	56
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

M4K4_HUMAN
NC score	0.072703 (rank : 1224)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	457	Target Neighborhood Hits	1589	Shared Neighborhood Hits	206
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CD72_MOUSE
NC score	0.072586 (rank : 1225)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	82
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

FA50B_MOUSE
NC score	0.072577 (rank : 1226)	θ value	4.03905 (rank : 393)
Query Neighborhood Hits	457	Target Neighborhood Hits	186	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTJ8, Q80X84, Q9D993	Gene names	Fam50b, D0H6S2654E, X5l
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

KIF6_HUMAN
NC score	0.072552 (rank : 1227)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	457	Target Neighborhood Hits	271	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

EXOC5_MOUSE
NC score	0.072386 (rank : 1228)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	457	Target Neighborhood Hits	194	Shared Neighborhood Hits	75
SwissProt Accessions	Q3TPX4	Gene names	Exoc5, Sec10l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 5 (Exocyst complex component Sec10).

K1C12_HUMAN
NC score	0.072357 (rank : 1229)	θ value	0.62314 (rank : 301)
Query Neighborhood Hits	457	Target Neighborhood Hits	372	Shared Neighborhood Hits	120
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

KIF17_MOUSE
NC score	0.072352 (rank : 1230)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	457	Target Neighborhood Hits	452	Shared Neighborhood Hits	112
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

TIM44_HUMAN
NC score	0.072212 (rank : 1231)	θ value	θ > 10 (rank : 1465)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	69
SwissProt Accessions	O43615, Q8N193	Gene names	TIMM44, MIMT44, TIM44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

LC7L2_HUMAN
NC score	0.071917 (rank : 1232)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

PCLO_HUMAN
NC score	0.071798 (rank : 1233)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	457	Target Neighborhood Hits	2046	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MYT1L_HUMAN
NC score	0.071776 (rank : 1234)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	457	Target Neighborhood Hits	471	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

MYPT1_HUMAN
NC score	0.071758 (rank : 1235)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	457	Target Neighborhood Hits	723	Shared Neighborhood Hits	149
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

TAK1L_MOUSE
NC score	0.071636 (rank : 1236)	θ value	θ > 10 (rank : 1435)
Query Neighborhood Hits	457	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	P58500	Gene names	Tak1l, ORF63
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

TAOK2_MOUSE
NC score	0.071555 (rank : 1237)	θ value	θ > 10 (rank : 1438)
Query Neighborhood Hits	457	Target Neighborhood Hits	1373	Shared Neighborhood Hits	191
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

M4K4_MOUSE
NC score	0.071008 (rank : 1238)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	457	Target Neighborhood Hits	1560	Shared Neighborhood Hits	201
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CNOT3_MOUSE
NC score	0.070901 (rank : 1239)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

GRB7_MOUSE
NC score	0.070854 (rank : 1240)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

BSN_MOUSE
NC score	0.070792 (rank : 1241)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	457	Target Neighborhood Hits	2057	Shared Neighborhood Hits	177
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FGD4_HUMAN
NC score	0.070679 (rank : 1242)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	457	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

GLU2B_HUMAN
NC score	0.070444 (rank : 1243)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	457	Target Neighborhood Hits	377	Shared Neighborhood Hits	79
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ARHGC_HUMAN
NC score	0.070367 (rank : 1244)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	457	Target Neighborhood Hits	351	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GBP1_MOUSE
NC score	0.070192 (rank : 1245)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	457	Target Neighborhood Hits	302	Shared Neighborhood Hits	91
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

PTRF_MOUSE
NC score	0.070175 (rank : 1246)	θ value	θ > 10 (rank : 1245)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	68
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

DAAM2_MOUSE
NC score	0.070155 (rank : 1247)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	457	Target Neighborhood Hits	371	Shared Neighborhood Hits	110
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

NSBP1_HUMAN
NC score	0.069995 (rank : 1248)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	457	Target Neighborhood Hits	251	Shared Neighborhood Hits	58
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

TEKT3_MOUSE
NC score	0.069794 (rank : 1249)	θ value	θ > 10 (rank : 1457)
Query Neighborhood Hits	457	Target Neighborhood Hits	123	Shared Neighborhood Hits	55
SwissProt Accessions	Q6X6Z7	Gene names	Tekt3
Domain Architecture	No domain graphic available
Description	Tektin-3.

FGD4_MOUSE
NC score	0.069782 (rank : 1250)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

NOE1_HUMAN
NC score	0.069421 (rank : 1251)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	115
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

SFR17_HUMAN
NC score	0.069415 (rank : 1252)	θ value	θ > 10 (rank : 1311)
Query Neighborhood Hits	457	Target Neighborhood Hits	325	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

RILP_HUMAN
NC score	0.069401 (rank : 1253)	θ value	θ > 10 (rank : 1266)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

MORC4_HUMAN
NC score	0.069305 (rank : 1254)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	457	Target Neighborhood Hits	244	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

RUSC2_HUMAN
NC score	0.069264 (rank : 1255)	θ value	θ > 10 (rank : 1286)
Query Neighborhood Hits	457	Target Neighborhood Hits	205	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

PDCD7_HUMAN
NC score	0.069263 (rank : 1256)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

RUSC2_MOUSE
NC score	0.069009 (rank : 1257)	θ value	θ > 10 (rank : 1287)
Query Neighborhood Hits	457	Target Neighborhood Hits	305	Shared Neighborhood Hits	61
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CNOT3_HUMAN
NC score	0.068883 (rank : 1258)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	457	Target Neighborhood Hits	425	Shared Neighborhood Hits	86
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ACTN4_MOUSE
NC score	0.068806 (rank : 1259)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	457	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

LNK_HUMAN
NC score	0.068805 (rank : 1260)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

TEX14_HUMAN
NC score	0.068770 (rank : 1261)	θ value	θ > 10 (rank : 1458)
Query Neighborhood Hits	457	Target Neighborhood Hits	1103	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

UN84A_HUMAN
NC score	0.068748 (rank : 1262)	θ value	θ > 10 (rank : 1525)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	76
SwissProt Accessions	O94901, Q96CZ7, Q9HA14, Q9UH98	Gene names	UNC84A, KIAA0810, SUN1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

TNNT1_HUMAN
NC score	0.068637 (rank : 1263)	θ value	θ > 10 (rank : 1478)
Query Neighborhood Hits	457	Target Neighborhood Hits	211	Shared Neighborhood Hits	77
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

APOA1_HUMAN
NC score	0.068582 (rank : 1264)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	457	Target Neighborhood Hits	262	Shared Neighborhood Hits	73
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

MINT_MOUSE
NC score	0.068531 (rank : 1265)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	457	Target Neighborhood Hits	1514	Shared Neighborhood Hits	133
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

WWC1_HUMAN
NC score	0.068378 (rank : 1266)	θ value	θ > 10 (rank : 1543)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

LNK_MOUSE
NC score	0.068311 (rank : 1267)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	457	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

K1C19_MOUSE
NC score	0.068028 (rank : 1268)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	457	Target Neighborhood Hits	358	Shared Neighborhood Hits	115
SwissProt Accessions	P19001	Gene names	Krt19, Krt1-19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

ECT2_MOUSE
NC score	0.067978 (rank : 1269)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	457	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

SEMG2_HUMAN
NC score	0.067899 (rank : 1270)	θ value	θ > 10 (rank : 1308)
Query Neighborhood Hits	457	Target Neighborhood Hits	251	Shared Neighborhood Hits	51
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

DJC17_HUMAN
NC score	0.067872 (rank : 1271)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NVM6	Gene names	DNAJC17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

LIMA1_HUMAN
NC score	0.067840 (rank : 1272)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	457	Target Neighborhood Hits	309	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MYPT2_HUMAN
NC score	0.067750 (rank : 1273)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	457	Target Neighborhood Hits	707	Shared Neighborhood Hits	148
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

KRHB6_MOUSE
NC score	0.067721 (rank : 1274)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	457	Target Neighborhood Hits	413	Shared Neighborhood Hits	125
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

CCD16_HUMAN
NC score	0.067717 (rank : 1275)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	70
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

ZN365_MOUSE
NC score	0.067494 (rank : 1276)	θ value	θ > 10 (rank : 1559)
Query Neighborhood Hits	457	Target Neighborhood Hits	193	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BG89, Q80TQ4, Q8BK39, Q8BXT2	Gene names	Znf365, Kiaa0844, Zfp365
Domain Architecture	No domain graphic available
Description	Protein ZNF365 (Su48).

ARHGC_MOUSE
NC score	0.067439 (rank : 1277)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

STX3_MOUSE
NC score	0.067436 (rank : 1278)	θ value	θ > 10 (rank : 1406)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	89
SwissProt Accessions	Q64704	Gene names	Stx3, Stx3a
Domain Architecture
Description	Syntaxin-3.

NPHP3_MOUSE
NC score	0.067266 (rank : 1279)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	457	Target Neighborhood Hits	335	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

GNRP_HUMAN
NC score	0.067252 (rank : 1280)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	457	Target Neighborhood Hits	239	Shared Neighborhood Hits	53
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

UVRAG_HUMAN
NC score	0.067169 (rank : 1281)	θ value	θ > 10 (rank : 1531)
Query Neighborhood Hits	457	Target Neighborhood Hits	150	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

MYT1L_MOUSE
NC score	0.067059 (rank : 1282)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	457	Target Neighborhood Hits	461	Shared Neighborhood Hits	111
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

SH21A_HUMAN
NC score	0.066940 (rank : 1283)	θ value	θ > 10 (rank : 1313)
Query Neighborhood Hits	457	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

DOT1L_HUMAN
NC score	0.066930 (rank : 1284)	θ value	5.27518 (rank : 403)
Query Neighborhood Hits	457	Target Neighborhood Hits	660	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

S6OS1_HUMAN
NC score	0.066812 (rank : 1285)	θ value	θ > 10 (rank : 1288)
Query Neighborhood Hits	457	Target Neighborhood Hits	134	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1H7	Gene names	SIX6OS1, C14orf39
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

UN84B_MOUSE
NC score	0.066776 (rank : 1286)	θ value	θ > 10 (rank : 1526)
Query Neighborhood Hits	457	Target Neighborhood Hits	194	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BJS4	Gene names	Unc84b, Sun2
Domain Architecture	No domain graphic available
Description	Sad1/unc-84-like protein 2.

GLU2B_MOUSE
NC score	0.066771 (rank : 1287)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	457	Target Neighborhood Hits	357	Shared Neighborhood Hits	79
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ECT2_HUMAN
NC score	0.066662 (rank : 1288)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	457	Target Neighborhood Hits	98	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

KI67_HUMAN
NC score	0.066642 (rank : 1289)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	457	Target Neighborhood Hits	581	Shared Neighborhood Hits	81
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

IQGA1_MOUSE
NC score	0.066612 (rank : 1290)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	457	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

APXL_HUMAN
NC score	0.066609 (rank : 1291)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	457	Target Neighborhood Hits	553	Shared Neighborhood Hits	77
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

STX3_HUMAN
NC score	0.066409 (rank : 1292)	θ value	θ > 10 (rank : 1405)
Query Neighborhood Hits	457	Target Neighborhood Hits	211	Shared Neighborhood Hits	89
SwissProt Accessions	Q13277, O43750, O43751, Q15360	Gene names	STX3, STX3A
Domain Architecture
Description	Syntaxin-3.

ACTN4_HUMAN
NC score	0.066260 (rank : 1293)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	457	Target Neighborhood Hits	279	Shared Neighborhood Hits	80
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

NUP54_MOUSE
NC score	0.066236 (rank : 1294)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BTS4, Q3TSI2, Q8BU42	Gene names	Nup54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

CRIP3_MOUSE
NC score	0.066223 (rank : 1295)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	457	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Q6R3, Q91V23, Q91V60	Gene names	Crip3, Tlp
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Thymus LIM protein) (m17TLP).

APC_HUMAN
NC score	0.066187 (rank : 1296)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	457	Target Neighborhood Hits	603	Shared Neighborhood Hits	108
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

TBCD4_HUMAN
NC score	0.066023 (rank : 1297)	θ value	θ > 10 (rank : 1444)
Query Neighborhood Hits	457	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

NOE1_MOUSE
NC score	0.065975 (rank : 1298)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	457	Target Neighborhood Hits	258	Shared Neighborhood Hits	111
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

T2_MOUSE
NC score	0.065638 (rank : 1299)	θ value	θ > 10 (rank : 1420)
Query Neighborhood Hits	457	Target Neighborhood Hits	140	Shared Neighborhood Hits	36
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

TRIM8_MOUSE
NC score	0.065266 (rank : 1300)	θ value	θ > 10 (rank : 1500)
Query Neighborhood Hits	457	Target Neighborhood Hits	674	Shared Neighborhood Hits	143
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BPTF_HUMAN
NC score	0.065225 (rank : 1301)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	457	Target Neighborhood Hits	786	Shared Neighborhood Hits	125
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SYBU_MOUSE
NC score	0.065126 (rank : 1302)	θ value	θ > 10 (rank : 1415)
Query Neighborhood Hits	457	Target Neighborhood Hits	214	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

ARHGB_HUMAN
NC score	0.065011 (rank : 1303)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	457	Target Neighborhood Hits	375	Shared Neighborhood Hits	44
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SMCE1_HUMAN
NC score	0.064915 (rank : 1304)	θ value	θ > 10 (rank : 1349)
Query Neighborhood Hits	457	Target Neighborhood Hits	272	Shared Neighborhood Hits	69
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

NPBL_MOUSE
NC score	0.064819 (rank : 1305)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	457	Target Neighborhood Hits	1041	Shared Neighborhood Hits	117
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NOL10_MOUSE
NC score	0.064705 (rank : 1306)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	457	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

LRC48_HUMAN
NC score	0.064592 (rank : 1307)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	457	Target Neighborhood Hits	324	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

VINC_HUMAN
NC score	0.064549 (rank : 1308)	θ value	θ > 10 (rank : 1536)
Query Neighborhood Hits	457	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

CTGE3_HUMAN
NC score	0.064427 (rank : 1309)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	457	Target Neighborhood Hits	77	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IX95	Gene names	CTAGE3
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 3 (cTAGE-3 protein).

ARHG1_HUMAN
NC score	0.064380 (rank : 1310)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	457	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

KRHB4_HUMAN
NC score	0.064334 (rank : 1311)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	457	Target Neighborhood Hits	352	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NSB2	Gene names	KRTHB4
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4).

TAD3L_HUMAN
NC score	0.064322 (rank : 1312)	θ value	θ > 10 (rank : 1429)
Query Neighborhood Hits	457	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TNIK_HUMAN
NC score	0.064281 (rank : 1313)	θ value	θ > 10 (rank : 1476)
Query Neighborhood Hits	457	Target Neighborhood Hits	1570	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

KRHB4_MOUSE
NC score	0.064192 (rank : 1314)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	457	Target Neighborhood Hits	344	Shared Neighborhood Hits	119
SwissProt Accessions	Q99M73	Gene names	Krthb4, Krt2-16
Domain Architecture
Description	Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4) (65 kDa type II keratin).

SH21A_MOUSE
NC score	0.064192 (rank : 1315)	θ value	θ > 10 (rank : 1314)
Query Neighborhood Hits	457	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

FGD3_MOUSE
NC score	0.064173 (rank : 1316)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	457	Target Neighborhood Hits	257	Shared Neighborhood Hits	28
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

KI13A_HUMAN
NC score	0.064171 (rank : 1317)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	457	Target Neighborhood Hits	359	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

TSKS_HUMAN
NC score	0.064121 (rank : 1318)	θ value	θ > 10 (rank : 1506)
Query Neighborhood Hits	457	Target Neighborhood Hits	220	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

SEMG1_HUMAN
NC score	0.064121 (rank : 1319)	θ value	θ > 10 (rank : 1307)
Query Neighborhood Hits	457	Target Neighborhood Hits	200	Shared Neighborhood Hits	48
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SRMS_HUMAN
NC score	0.064105 (rank : 1320)	θ value	θ > 10 (rank : 1376)
Query Neighborhood Hits	457	Target Neighborhood Hits	946	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

HIRP3_HUMAN
NC score	0.064037 (rank : 1321)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	457	Target Neighborhood Hits	323	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

RHG25_MOUSE
NC score	0.063840 (rank : 1322)	θ value	θ > 10 (rank : 1264)
Query Neighborhood Hits	457	Target Neighborhood Hits	492	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MATK_MOUSE
NC score	0.063794 (rank : 1323)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	457	Target Neighborhood Hits	952	Shared Neighborhood Hits	87
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

HSF2B_HUMAN
NC score	0.063777 (rank : 1324)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	457	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

PFD4_HUMAN
NC score	0.063768 (rank : 1325)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	457	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQP4, Q5TD11, Q92779	Gene names	PFDN4, PFD4
Domain Architecture	No domain graphic available
Description	Prefoldin subunit 4 (Protein C-1).

ST18_HUMAN
NC score	0.063658 (rank : 1326)	θ value	θ > 10 (rank : 1379)
Query Neighborhood Hits	457	Target Neighborhood Hits	252	Shared Neighborhood Hits	91
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

TAD3L_MOUSE
NC score	0.063648 (rank : 1327)	θ value	θ > 10 (rank : 1430)
Query Neighborhood Hits	457	Target Neighborhood Hits	188	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

SDCG1_HUMAN
NC score	0.063634 (rank : 1328)	θ value	θ > 10 (rank : 1299)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

GRB7_HUMAN
NC score	0.063543 (rank : 1329)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	48
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

KLC4_MOUSE
NC score	0.063458 (rank : 1330)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	457	Target Neighborhood Hits	336	Shared Neighborhood Hits	108
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

FGD2_MOUSE
NC score	0.063427 (rank : 1331)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	457	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD2_HUMAN
NC score	0.063411 (rank : 1332)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	457	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

GEMI_HUMAN
NC score	0.063368 (rank : 1333)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	457	Target Neighborhood Hits	192	Shared Neighborhood Hits	51
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

GOPC_HUMAN
NC score	0.063343 (rank : 1334)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	457	Target Neighborhood Hits	377	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

PFD6_HUMAN
NC score	0.063276 (rank : 1335)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	457	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

LCP2_MOUSE
NC score	0.063167 (rank : 1336)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CIP1_HUMAN
NC score	0.063077 (rank : 1337)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	457	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPC3	Gene names	CCNB1IP1, C14orf18, HEI10
Domain Architecture	No domain graphic available
Description	Cyclin-B1-interacting protein 1 (EC 6.3.2.-) (Human enhancer of invasion 10) (E3 ubiquitin-protein ligase HEI10).

BST2_HUMAN
NC score	0.062956 (rank : 1338)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	457	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	Q10589, Q53G07	Gene names	BST2
Domain Architecture
Description	Bone marrow stromal antigen 2 precursor (BST-2) (CD317 antigen) (HM1.24 antigen).

RP1L1_HUMAN
NC score	0.062526 (rank : 1339)	θ value	θ > 10 (rank : 1275)
Query Neighborhood Hits	457	Target Neighborhood Hits	1072	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

LAMA1_MOUSE
NC score	0.062520 (rank : 1340)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	457	Target Neighborhood Hits	838	Shared Neighborhood Hits	135
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SAKS1_MOUSE
NC score	0.062516 (rank : 1341)	θ value	θ > 10 (rank : 1293)
Query Neighborhood Hits	457	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

N4BP3_MOUSE
NC score	0.062415 (rank : 1342)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C7U1, Q3TDC7, Q7TNR2, Q922W0, Q99J06	Gene names	N4bp3
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

RN168_MOUSE
NC score	0.062370 (rank : 1343)	θ value	θ > 10 (rank : 1270)
Query Neighborhood Hits	457	Target Neighborhood Hits	440	Shared Neighborhood Hits	81
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

NRBF2_HUMAN
NC score	0.062342 (rank : 1344)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	457	Target Neighborhood Hits	122	Shared Neighborhood Hits	54
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

FGD3_HUMAN
NC score	0.062340 (rank : 1345)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

GRB10_MOUSE
NC score	0.062219 (rank : 1346)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	46
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

LRMP_HUMAN
NC score	0.062085 (rank : 1347)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

SYBU_HUMAN
NC score	0.062033 (rank : 1348)	θ value	θ > 10 (rank : 1414)
Query Neighborhood Hits	457	Target Neighborhood Hits	188	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

MATK_HUMAN
NC score	0.062012 (rank : 1349)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	457	Target Neighborhood Hits	954	Shared Neighborhood Hits	80
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

KLC4_HUMAN
NC score	0.061949 (rank : 1350)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	457	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

RIF1_HUMAN
NC score	0.061918 (rank : 1351)	θ value	θ > 10 (rank : 1265)
Query Neighborhood Hits	457	Target Neighborhood Hits	320	Shared Neighborhood Hits	76
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

MUTED_HUMAN
NC score	0.061829 (rank : 1352)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	457	Target Neighborhood Hits	134	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TDH9, Q5THS1, Q68D56, Q8N5F9, Q9NU16	Gene names	MUTED
Domain Architecture	No domain graphic available
Description	Muted protein homolog.

TMCC3_HUMAN
NC score	0.061797 (rank : 1353)	θ value	θ > 10 (rank : 1472)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

ANR38_MOUSE
NC score	0.061765 (rank : 1354)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	457	Target Neighborhood Hits	512	Shared Neighborhood Hits	95
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

WWC3_HUMAN
NC score	0.061756 (rank : 1355)	θ value	θ > 10 (rank : 1545)
Query Neighborhood Hits	457	Target Neighborhood Hits	193	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

PALM_HUMAN
NC score	0.061692 (rank : 1356)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	457	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	O75781, O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3	Gene names	PALM, KIAA0270
Domain Architecture
Description	Paralemmin.

SH22A_MOUSE
NC score	0.061658 (rank : 1357)	θ value	θ > 10 (rank : 1318)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

LBC_HUMAN
NC score	0.061630 (rank : 1358)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	457	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

F107A_HUMAN
NC score	0.061620 (rank : 1359)	θ value	0.62314 (rank : 299)
Query Neighborhood Hits	457	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	O95990, Q96NH4	Gene names	FAM107A, DRR1, TU3A
Domain Architecture
Description	Protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A).

NOC3L_MOUSE
NC score	0.061516 (rank : 1360)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

K1C19_HUMAN
NC score	0.061404 (rank : 1361)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	457	Target Neighborhood Hits	320	Shared Neighborhood Hits	112
SwissProt Accessions	P08727, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4	Gene names	KRT19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

CCD50_MOUSE
NC score	0.061040 (rank : 1362)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	457	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

DYXC1_HUMAN
NC score	0.060569 (rank : 1363)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	457	Target Neighborhood Hits	261	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

GRB10_HUMAN
NC score	0.060535 (rank : 1364)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	457	Target Neighborhood Hits	147	Shared Neighborhood Hits	44
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

SOCS7_MOUSE
NC score	0.060512 (rank : 1365)	θ value	θ > 10 (rank : 1359)
Query Neighborhood Hits	457	Target Neighborhood Hits	154	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

FA44A_HUMAN
NC score	0.060428 (rank : 1366)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	457	Target Neighborhood Hits	280	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

ATIF1_MOUSE
NC score	0.060311 (rank : 1367)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	457	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	O35143	Gene names	Atpif1, Atpi, If1
Domain Architecture
Description	ATPase inhibitor, mitochondrial precursor.

UBXD2_HUMAN
NC score	0.060178 (rank : 1368)	θ value	θ > 10 (rank : 1524)
Query Neighborhood Hits	457	Target Neighborhood Hits	241	Shared Neighborhood Hits	68
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

LIMD2_MOUSE
NC score	0.060177 (rank : 1369)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	457	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGB5	Gene names	Limd2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

XRCC4_HUMAN
NC score	0.060122 (rank : 1370)	θ value	θ > 10 (rank : 1549)
Query Neighborhood Hits	457	Target Neighborhood Hits	131	Shared Neighborhood Hits	50
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

PFD1_HUMAN
NC score	0.060089 (rank : 1371)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	457	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	O60925, Q53F95, Q96EX6	Gene names	PFDN1, PFD1
Domain Architecture
Description	Prefoldin subunit 1.

CIR_HUMAN
NC score	0.060053 (rank : 1372)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	457	Target Neighborhood Hits	249	Shared Neighborhood Hits	60
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

SAKS1_HUMAN
NC score	0.060051 (rank : 1373)	θ value	θ > 10 (rank : 1292)
Query Neighborhood Hits	457	Target Neighborhood Hits	202	Shared Neighborhood Hits	51
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SEPT7_HUMAN
NC score	0.060023 (rank : 1374)	θ value	θ > 10 (rank : 1309)
Query Neighborhood Hits	457	Target Neighborhood Hits	385	Shared Neighborhood Hits	117
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

ARHG1_MOUSE
NC score	0.059905 (rank : 1375)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	27
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

BRD4_MOUSE
NC score	0.059662 (rank : 1376)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	457	Target Neighborhood Hits	845	Shared Neighborhood Hits	136
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CRIP2_MOUSE
NC score	0.059582 (rank : 1377)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	457	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCT8	Gene names	Crip2, Crp2, Hlp
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Heart LIM protein).

NPHP3_HUMAN
NC score	0.059412 (rank : 1378)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	457	Target Neighborhood Hits	304	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

TAK1L_HUMAN
NC score	0.059295 (rank : 1379)	θ value	θ > 10 (rank : 1434)
Query Neighborhood Hits	457	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

APS_MOUSE
NC score	0.059287 (rank : 1380)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	457	Target Neighborhood Hits	134	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

GNRP_MOUSE
NC score	0.059257 (rank : 1381)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	457	Target Neighborhood Hits	191	Shared Neighborhood Hits	36
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ST18_MOUSE
NC score	0.059159 (rank : 1382)	θ value	θ > 10 (rank : 1380)
Query Neighborhood Hits	457	Target Neighborhood Hits	248	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

CCDC5_MOUSE
NC score	0.059062 (rank : 1383)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	457	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BHX1, Q3UIH2, Q8R1M1	Gene names	Ccdc5
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5.

SH22A_HUMAN
NC score	0.058901 (rank : 1384)	θ value	θ > 10 (rank : 1317)
Query Neighborhood Hits	457	Target Neighborhood Hits	144	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

LIMD2_HUMAN
NC score	0.058891 (rank : 1385)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	457	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BT23, Q96S91	Gene names	LIMD2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

PTN11_HUMAN
NC score	0.058807 (rank : 1386)	θ value	θ > 10 (rank : 1242)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	54
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

WWC1_MOUSE
NC score	0.058767 (rank : 1387)	θ value	θ > 10 (rank : 1544)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	78
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

AKAP2_HUMAN
NC score	0.058687 (rank : 1388)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	457	Target Neighborhood Hits	507	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

NCOR2_HUMAN
NC score	0.058673 (rank : 1389)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	457	Target Neighborhood Hits	870	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

KIF17_HUMAN
NC score	0.058658 (rank : 1390)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	457	Target Neighborhood Hits	365	Shared Neighborhood Hits	102
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

K1C23_HUMAN
NC score	0.058643 (rank : 1391)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	457	Target Neighborhood Hits	312	Shared Neighborhood Hits	107
SwissProt Accessions	Q9C075, Q9NUR6	Gene names	KRT23
Domain Architecture
Description	Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23).

PTN11_MOUSE
NC score	0.058632 (rank : 1392)	θ value	θ > 10 (rank : 1243)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

IWS1_HUMAN
NC score	0.058464 (rank : 1393)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	457	Target Neighborhood Hits	1241	Shared Neighborhood Hits	116
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CREB3_HUMAN
NC score	0.058426 (rank : 1394)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	457	Target Neighborhood Hits	138	Shared Neighborhood Hits	51
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

SNIP_HUMAN
NC score	0.058414 (rank : 1395)	θ value	θ > 10 (rank : 1351)
Query Neighborhood Hits	457	Target Neighborhood Hits	313	Shared Neighborhood Hits	71
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

PLDN_HUMAN
NC score	0.058414 (rank : 1396)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	457	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UL45	Gene names	PLDN, PA
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein).

DYDC1_HUMAN
NC score	0.058390 (rank : 1397)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	457	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWB3, Q5QP03, Q5QP04, Q6WNP4, Q6ZU87	Gene names	DYDC1, DPY30D1
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 1 (RSD-9).

DTNB_HUMAN
NC score	0.058367 (rank : 1398)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	457	Target Neighborhood Hits	255	Shared Neighborhood Hits	89
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

SEPT7_MOUSE
NC score	0.058344 (rank : 1399)	θ value	θ > 10 (rank : 1310)
Query Neighborhood Hits	457	Target Neighborhood Hits	327	Shared Neighborhood Hits	100
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

CRIP2_HUMAN
NC score	0.058221 (rank : 1400)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	457	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	P52943	Gene names	CRIP2, CRP2
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Protein ESP1).

ARHG2_HUMAN
NC score	0.058195 (rank : 1401)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	457	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

EM55_HUMAN
NC score	0.058039 (rank : 1402)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

BRD4_HUMAN
NC score	0.058034 (rank : 1403)	θ value	3.0926 (rank : 376)
Query Neighborhood Hits	457	Target Neighborhood Hits	851	Shared Neighborhood Hits	136
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

GBP5_MOUSE
NC score	0.058026 (rank : 1404)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

GIMA4_HUMAN
NC score	0.058000 (rank : 1405)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

YTDC1_HUMAN
NC score	0.057783 (rank : 1406)	θ value	θ > 10 (rank : 1551)
Query Neighborhood Hits	457	Target Neighborhood Hits	458	Shared Neighborhood Hits	80
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

DTNA_HUMAN
NC score	0.057759 (rank : 1407)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	457	Target Neighborhood Hits	295	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

SH2D3_MOUSE
NC score	0.057554 (rank : 1408)	θ value	θ > 10 (rank : 1322)
Query Neighborhood Hits	457	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

PALM_MOUSE
NC score	0.057385 (rank : 1409)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	457	Target Neighborhood Hits	228	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

ARHG2_MOUSE
NC score	0.057348 (rank : 1410)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	457	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

K1H5_HUMAN
NC score	0.057267 (rank : 1411)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	457	Target Neighborhood Hits	362	Shared Neighborhood Hits	100
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

K1377_HUMAN
NC score	0.057235 (rank : 1412)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	457	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2H0, Q4G0U6	Gene names	KIAA1377
Domain Architecture	No domain graphic available
Description	Protein KIAA1377.

UT14C_HUMAN
NC score	0.057222 (rank : 1413)	θ value	θ > 10 (rank : 1528)
Query Neighborhood Hits	457	Target Neighborhood Hits	217	Shared Neighborhood Hits	68
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

FMNL_MOUSE
NC score	0.057115 (rank : 1414)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	457	Target Neighborhood Hits	428	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

LIMA1_MOUSE
NC score	0.057086 (rank : 1415)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	457	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

TR150_MOUSE
NC score	0.057074 (rank : 1416)	θ value	θ > 10 (rank : 1490)
Query Neighborhood Hits	457	Target Neighborhood Hits	468	Shared Neighborhood Hits	76
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

BIN3_HUMAN
NC score	0.057052 (rank : 1417)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	457	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQY0, Q9BVG2, Q9NVY9	Gene names	BIN3
Domain Architecture
Description	Bridging integrator 3.

KRHB5_HUMAN
NC score	0.057050 (rank : 1418)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	457	Target Neighborhood Hits	321	Shared Neighborhood Hits	106
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

ZN638_HUMAN
NC score	0.057042 (rank : 1419)	θ value	θ > 10 (rank : 1560)
Query Neighborhood Hits	457	Target Neighborhood Hits	343	Shared Neighborhood Hits	78
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

BRD3_MOUSE
NC score	0.056948 (rank : 1420)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	457	Target Neighborhood Hits	402	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

ING3_MOUSE
NC score	0.056945 (rank : 1421)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

THOC2_HUMAN
NC score	0.056933 (rank : 1422)	θ value	θ > 10 (rank : 1462)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

PCQAP_HUMAN
NC score	0.056868 (rank : 1423)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	457	Target Neighborhood Hits	549	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

TRAF5_MOUSE
NC score	0.056773 (rank : 1424)	θ value	θ > 10 (rank : 1494)
Query Neighborhood Hits	457	Target Neighborhood Hits	355	Shared Neighborhood Hits	81
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

NARGL_HUMAN
NC score	0.056757 (rank : 1425)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	457	Target Neighborhood Hits	222	Shared Neighborhood Hits	77
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

ACTN2_HUMAN
NC score	0.056605 (rank : 1426)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	457	Target Neighborhood Hits	295	Shared Neighborhood Hits	79
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

CT077_HUMAN
NC score	0.056473 (rank : 1427)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	457	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

UT14A_MOUSE
NC score	0.056267 (rank : 1428)	θ value	θ > 10 (rank : 1527)
Query Neighborhood Hits	457	Target Neighborhood Hits	177	Shared Neighborhood Hits	65
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

ZC11A_MOUSE
NC score	0.056213 (rank : 1429)	θ value	θ > 10 (rank : 1554)
Query Neighborhood Hits	457	Target Neighborhood Hits	216	Shared Neighborhood Hits	50
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

TLK2_MOUSE
NC score	0.056098 (rank : 1430)	θ value	θ > 10 (rank : 1469)
Query Neighborhood Hits	457	Target Neighborhood Hits	1088	Shared Neighborhood Hits	156
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

BCAR3_HUMAN
NC score	0.056077 (rank : 1431)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	42
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

NCOR2_MOUSE
NC score	0.056073 (rank : 1432)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	457	Target Neighborhood Hits	790	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

ANGL3_MOUSE
NC score	0.056029 (rank : 1433)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	457	Target Neighborhood Hits	306	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

FBX28_HUMAN
NC score	0.055978 (rank : 1434)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	457	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

APC_MOUSE
NC score	0.055875 (rank : 1435)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	457	Target Neighborhood Hits	441	Shared Neighborhood Hits	86
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

FA76B_HUMAN
NC score	0.055865 (rank : 1436)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	457	Target Neighborhood Hits	184	Shared Neighborhood Hits	66
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

SPC24_MOUSE
NC score	0.055787 (rank : 1437)	θ value	θ > 10 (rank : 1363)
Query Neighborhood Hits	457	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D083, Q3TIF5, Q8CD13	Gene names	Spbc24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24.

LAMA1_HUMAN
NC score	0.055655 (rank : 1438)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	457	Target Neighborhood Hits	804	Shared Neighborhood Hits	111
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

CT077_MOUSE
NC score	0.055530 (rank : 1439)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	457	Target Neighborhood Hits	122	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

FGD6_MOUSE
NC score	0.055522 (rank : 1440)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	457	Target Neighborhood Hits	282	Shared Neighborhood Hits	36
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD1_HUMAN
NC score	0.055447 (rank : 1441)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	457	Target Neighborhood Hits	367	Shared Neighborhood Hits	37
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

DAB2P_MOUSE
NC score	0.055433 (rank : 1442)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	457	Target Neighborhood Hits	284	Shared Neighborhood Hits	80
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

CCD94_HUMAN
NC score	0.055427 (rank : 1443)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	457	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BW85, O75270, Q9H862, Q9NW16	Gene names	CCDC94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

SH2D3_HUMAN
NC score	0.055419 (rank : 1444)	θ value	θ > 10 (rank : 1321)
Query Neighborhood Hits	457	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

UTP11_HUMAN
NC score	0.055303 (rank : 1445)	θ value	θ > 10 (rank : 1529)
Query Neighborhood Hits	457	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y3A2, Q5VT93, Q9BS98, Q9NS31	Gene names	UTP11L
Domain Architecture
Description	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA- associated protein 11) (UTP11-like protein).

RBNS5_MOUSE
NC score	0.055215 (rank : 1446)	θ value	θ > 10 (rank : 1255)
Query Neighborhood Hits	457	Target Neighborhood Hits	266	Shared Neighborhood Hits	58
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

EM55_MOUSE
NC score	0.055106 (rank : 1447)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	457	Target Neighborhood Hits	221	Shared Neighborhood Hits	73
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

MINK1_HUMAN
NC score	0.055029 (rank : 1448)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	457	Target Neighborhood Hits	1477	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

E41L2_MOUSE
NC score	0.055012 (rank : 1449)	θ value	0.0736092 (rank : 208)
Query Neighborhood Hits	457	Target Neighborhood Hits	459	Shared Neighborhood Hits	92
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MINK1_MOUSE
NC score	0.054999 (rank : 1450)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	457	Target Neighborhood Hits	1451	Shared Neighborhood Hits	177
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SASH1_HUMAN
NC score	0.054948 (rank : 1451)	θ value	θ > 10 (rank : 1295)
Query Neighborhood Hits	457	Target Neighborhood Hits	292	Shared Neighborhood Hits	57
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

GCF_HUMAN
NC score	0.054921 (rank : 1452)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	457	Target Neighborhood Hits	107	Shared Neighborhood Hits	48
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

S6OS1_MOUSE
NC score	0.054885 (rank : 1453)	θ value	θ > 10 (rank : 1289)
Query Neighborhood Hits	457	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

MAP2_MOUSE
NC score	0.054555 (rank : 1454)	θ value	2.36792 (rank : 367)
Query Neighborhood Hits	457	Target Neighborhood Hits	342	Shared Neighborhood Hits	59
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

DAB2P_HUMAN
NC score	0.054543 (rank : 1455)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	457	Target Neighborhood Hits	303	Shared Neighborhood Hits	80
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

CRIP3_HUMAN
NC score	0.054530 (rank : 1456)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	457	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q6Q6R5, Q5T043, Q6Q6R4, Q6Q6R6, Q6Q6R7	Gene names	CRIP3
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Chromosome 6 LIM-only protein) (h6LIMo).

NUP54_HUMAN
NC score	0.054517 (rank : 1457)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	457	Target Neighborhood Hits	93	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z3B4, Q96EA7, Q9NVL5, Q9P0I1	Gene names	NUP54
Domain Architecture	No domain graphic available
Description	Nucleoporin p54 (54 kDa nucleoporin).

NSBP1_MOUSE
NC score	0.054493 (rank : 1458)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	457	Target Neighborhood Hits	681	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

CN140_MOUSE
NC score	0.054482 (rank : 1459)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	457	Target Neighborhood Hits	152	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CCG1, Q8CCM8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf140 homolog.

TMCC3_MOUSE
NC score	0.054360 (rank : 1460)	θ value	θ > 10 (rank : 1473)
Query Neighborhood Hits	457	Target Neighborhood Hits	192	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

ING3_HUMAN
NC score	0.054318 (rank : 1461)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	457	Target Neighborhood Hits	178	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

RFC1_MOUSE
NC score	0.054253 (rank : 1462)	θ value	θ > 10 (rank : 1258)
Query Neighborhood Hits	457	Target Neighborhood Hits	290	Shared Neighborhood Hits	67
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

PCLO_MOUSE
NC score	0.054208 (rank : 1463)	θ value	1.81305 (rank : 350)
Query Neighborhood Hits	457	Target Neighborhood Hits	2275	Shared Neighborhood Hits	167
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

K1914_MOUSE
NC score	0.054201 (rank : 1464)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	457	Target Neighborhood Hits	216	Shared Neighborhood Hits	50
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

RRP5_HUMAN
NC score	0.054065 (rank : 1465)	θ value	θ > 10 (rank : 1279)
Query Neighborhood Hits	457	Target Neighborhood Hits	291	Shared Neighborhood Hits	75
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

MDN1_HUMAN
NC score	0.054033 (rank : 1466)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	457	Target Neighborhood Hits	662	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

ACTN3_MOUSE
NC score	0.054012 (rank : 1467)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	457	Target Neighborhood Hits	265	Shared Neighborhood Hits	75
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

TAF4_HUMAN
NC score	0.053884 (rank : 1468)	θ value	θ > 10 (rank : 1431)
Query Neighborhood Hits	457	Target Neighborhood Hits	687	Shared Neighborhood Hits	92
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

KI18A_MOUSE
NC score	0.053795 (rank : 1469)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	73
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

TCAL5_HUMAN
NC score	0.053765 (rank : 1470)	θ value	θ > 10 (rank : 1445)
Query Neighborhood Hits	457	Target Neighborhood Hits	806	Shared Neighborhood Hits	86
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

LCP2_HUMAN
NC score	0.053744 (rank : 1471)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	457	Target Neighborhood Hits	531	Shared Neighborhood Hits	62
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SOCS6_MOUSE
NC score	0.053734 (rank : 1472)	θ value	θ > 10 (rank : 1358)
Query Neighborhood Hits	457	Target Neighborhood Hits	146	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

FARP2_MOUSE
NC score	0.053729 (rank : 1473)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	457	Target Neighborhood Hits	209	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

BCAR3_MOUSE
NC score	0.053687 (rank : 1474)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	457	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

MILK2_HUMAN
NC score	0.053679 (rank : 1475)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	457	Target Neighborhood Hits	457	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

DJC18_MOUSE
NC score	0.053446 (rank : 1476)	θ value	0.00228821 (rank : 115)
Query Neighborhood Hits	457	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CZJ9, Q8R371	Gene names	Dnajc18
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 18.

SCG2_HUMAN
NC score	0.053284 (rank : 1477)	θ value	θ > 10 (rank : 1297)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

CCD94_MOUSE
NC score	0.053274 (rank : 1478)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	457	Target Neighborhood Hits	127	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D6J3	Gene names	Ccdc94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

PELP1_HUMAN
NC score	0.053195 (rank : 1479)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	457	Target Neighborhood Hits	596	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CL025_HUMAN
NC score	0.053193 (rank : 1480)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	457	Target Neighborhood Hits	179	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

GO45_MOUSE
NC score	0.053190 (rank : 1481)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	457	Target Neighborhood Hits	139	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

BRD3_HUMAN
NC score	0.053174 (rank : 1482)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	457	Target Neighborhood Hits	369	Shared Neighborhood Hits	87
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

ZN365_HUMAN
NC score	0.053134 (rank : 1483)	θ value	θ > 10 (rank : 1558)
Query Neighborhood Hits	457	Target Neighborhood Hits	145	Shared Neighborhood Hits	57
SwissProt Accessions	Q70YC5, O94930, Q5HYE6, Q68SG8, Q6NSK2, Q6P9D4, Q70YC6, Q70YC7	Gene names	ZNF365, KIAA0844
Domain Architecture	No domain graphic available
Description	Protein ZNF365.

MORC4_MOUSE
NC score	0.053131 (rank : 1484)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	457	Target Neighborhood Hits	235	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

FA76B_MOUSE
NC score	0.053042 (rank : 1485)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	457	Target Neighborhood Hits	181	Shared Neighborhood Hits	65
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FGD1_MOUSE
NC score	0.052913 (rank : 1486)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	457	Target Neighborhood Hits	387	Shared Neighborhood Hits	32
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

BMX_HUMAN
NC score	0.052850 (rank : 1487)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	457	Target Neighborhood Hits	942	Shared Neighborhood Hits	67
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CHIN_MOUSE
NC score	0.052764 (rank : 1488)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	457	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

COG6_HUMAN
NC score	0.052735 (rank : 1489)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	457	Target Neighborhood Hits	118	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2V7, Q5T0U1, Q9ULT5	Gene names	COG6, KIAA1134
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

SIL1_MOUSE
NC score	0.052667 (rank : 1490)	θ value	θ > 10 (rank : 1336)
Query Neighborhood Hits	457	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q9EPK6, Q91V34	Gene names	Sil1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor.

HGS_HUMAN
NC score	0.052657 (rank : 1491)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	457	Target Neighborhood Hits	517	Shared Neighborhood Hits	69
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

DFFA_HUMAN
NC score	0.052594 (rank : 1492)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	457	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	O00273, Q96I97, Q9Y6C6	Gene names	DFFA, DFF1, DFF45
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

CD008_HUMAN
NC score	0.052530 (rank : 1493)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	457	Target Neighborhood Hits	330	Shared Neighborhood Hits	65
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

BMX_MOUSE
NC score	0.052455 (rank : 1494)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	457	Target Neighborhood Hits	912	Shared Neighborhood Hits	64
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

ZAP70_MOUSE
NC score	0.052405 (rank : 1495)	θ value	θ > 10 (rank : 1553)
Query Neighborhood Hits	457	Target Neighborhood Hits	905	Shared Neighborhood Hits	66
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

DJC18_HUMAN
NC score	0.052394 (rank : 1496)	θ value	0.00134147 (rank : 105)
Query Neighborhood Hits	457	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H819	Gene names	DNAJC18
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 18.

MICA1_HUMAN
NC score	0.052360 (rank : 1497)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	457	Target Neighborhood Hits	279	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

VINC_MOUSE
NC score	0.052133 (rank : 1498)	θ value	θ > 10 (rank : 1537)
Query Neighborhood Hits	457	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

CHCH6_MOUSE
NC score	0.052112 (rank : 1499)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	457	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VN4	Gene names	Chchd6
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.

DHX16_HUMAN
NC score	0.052073 (rank : 1500)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	457	Target Neighborhood Hits	356	Shared Neighborhood Hits	107
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

SOCS6_HUMAN
NC score	0.051947 (rank : 1501)	θ value	θ > 10 (rank : 1357)
Query Neighborhood Hits	457	Target Neighborhood Hits	126	Shared Neighborhood Hits	37
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

KRHB5_MOUSE
NC score	0.051839 (rank : 1502)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	457	Target Neighborhood Hits	294	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

DEK_MOUSE
NC score	0.051814 (rank : 1503)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	457	Target Neighborhood Hits	280	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

ZAP70_HUMAN
NC score	0.051644 (rank : 1504)	θ value	θ > 10 (rank : 1552)
Query Neighborhood Hits	457	Target Neighborhood Hits	893	Shared Neighborhood Hits	66
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

DIAP2_HUMAN
NC score	0.051493 (rank : 1505)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	457	Target Neighborhood Hits	342	Shared Neighborhood Hits	92
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

STX2_HUMAN
NC score	0.051428 (rank : 1506)	θ value	θ > 10 (rank : 1404)
Query Neighborhood Hits	457	Target Neighborhood Hits	158	Shared Neighborhood Hits	72
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

HGS_MOUSE
NC score	0.051401 (rank : 1507)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	457	Target Neighborhood Hits	589	Shared Neighborhood Hits	69
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MDC1_HUMAN
NC score	0.051236 (rank : 1508)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	457	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MTSS1_HUMAN
NC score	0.050939 (rank : 1509)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	457	Target Neighborhood Hits	504	Shared Neighborhood Hits	66
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

FGD6_HUMAN
NC score	0.050934 (rank : 1510)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	457	Target Neighborhood Hits	237	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FCER2_MOUSE
NC score	0.050903 (rank : 1511)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	457	Target Neighborhood Hits	392	Shared Neighborhood Hits	103
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

DTNB_MOUSE
NC score	0.050888 (rank : 1512)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	77
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

IWS1_MOUSE
NC score	0.050852 (rank : 1513)	θ value	5.27518 (rank : 405)
Query Neighborhood Hits	457	Target Neighborhood Hits	1258	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KSYK_MOUSE
NC score	0.050846 (rank : 1514)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	457	Target Neighborhood Hits	944	Shared Neighborhood Hits	68
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

CHIN_HUMAN
NC score	0.050804 (rank : 1515)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	457	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

SASH1_MOUSE
NC score	0.050485 (rank : 1516)	θ value	θ > 10 (rank : 1296)
Query Neighborhood Hits	457	Target Neighborhood Hits	263	Shared Neighborhood Hits	59
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

CHIO_HUMAN
NC score	0.050466 (rank : 1517)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	457	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TPX2_HUMAN
NC score	0.050417 (rank : 1518)	θ value	θ > 10 (rank : 1489)
Query Neighborhood Hits	457	Target Neighborhood Hits	150	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

FEZ2_MOUSE
NC score	0.050373 (rank : 1519)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	457	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

KSYK_HUMAN
NC score	0.050324 (rank : 1520)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	457	Target Neighborhood Hits	901	Shared Neighborhood Hits	65
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

FARP2_HUMAN
NC score	0.050259 (rank : 1521)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	457	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

CT172_MOUSE
NC score	0.050258 (rank : 1522)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	457	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CYC5, Q9CYF2, Q9DA26	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172 homolog.

DEK_HUMAN
NC score	0.049549 (rank : 1523)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	457	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

DDX23_HUMAN
NC score	0.048390 (rank : 1524)	θ value	6.88961 (rank : 425)
Query Neighborhood Hits	457	Target Neighborhood Hits	486	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

NOP56_MOUSE
NC score	0.048330 (rank : 1525)	θ value	0.0961366 (rank : 226)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D6Z1, Q3UD45, Q8BVL1, Q8VDT2, Q99LT8, Q9CT15	Gene names	Nol5a, Nop56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

SC15B_HUMAN
NC score	0.048217 (rank : 1526)	θ value	1.38821 (rank : 337)
Query Neighborhood Hits	457	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2D4	Gene names	SEC15L2, KIAA0919, SEC15B
Domain Architecture
Description	Exocyst complex component Sec15B.

S3TC2_MOUSE
NC score	0.048061 (rank : 1527)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	457	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

SIL1_HUMAN
NC score	0.046188 (rank : 1528)	θ value	1.81305 (rank : 354)
Query Neighborhood Hits	457	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H173, Q8N2L3	Gene names	SIL1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP).

NKTR_HUMAN
NC score	0.044726 (rank : 1529)	θ value	2.36792 (rank : 370)
Query Neighborhood Hits	457	Target Neighborhood Hits	658	Shared Neighborhood Hits	90
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

IF5_HUMAN
NC score	0.043352 (rank : 1530)	θ value	0.813845 (rank : 311)
Query Neighborhood Hits	457	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

K0423_HUMAN
NC score	0.042978 (rank : 1531)	θ value	0.125558 (rank : 237)
Query Neighborhood Hits	457	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

IF5_MOUSE
NC score	0.042620 (rank : 1532)	θ value	0.813845 (rank : 312)
Query Neighborhood Hits	457	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

TR150_HUMAN
NC score	0.041724 (rank : 1533)	θ value	4.03905 (rank : 398)
Query Neighborhood Hits	457	Target Neighborhood Hits	313	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ERCC4_MOUSE
NC score	0.041376 (rank : 1534)	θ value	0.125558 (rank : 235)
Query Neighborhood Hits	457	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

DNJC7_MOUSE
NC score	0.041279 (rank : 1535)	θ value	0.0431538 (rank : 191)
Query Neighborhood Hits	457	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

DNJC7_HUMAN
NC score	0.039351 (rank : 1536)	θ value	0.163984 (rank : 244)
Query Neighborhood Hits	457	Target Neighborhood Hits	212	Shared Neighborhood Hits	22
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

NEK1_MOUSE
NC score	0.037960 (rank : 1537)	θ value	2.36792 (rank : 369)
Query Neighborhood Hits	457	Target Neighborhood Hits	1311	Shared Neighborhood Hits	150
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

LMD1_HUMAN
NC score	0.034827 (rank : 1538)	θ value	3.0926 (rank : 382)
Query Neighborhood Hits	457	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

AP3D1_HUMAN
NC score	0.033516 (rank : 1539)	θ value	1.06291 (rank : 321)
Query Neighborhood Hits	457	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

IFIT3_MOUSE
NC score	0.030177 (rank : 1540)	θ value	0.279714 (rank : 262)
Query Neighborhood Hits	457	Target Neighborhood Hits	61	Shared Neighborhood Hits	15
SwissProt Accessions	Q64345, Q99L62	Gene names	Ifit3, Garg49, Ifi49
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (Glucocorticoid-attenuated response gene 49 protein) (GARG-49) (IRG2).

MAP4_HUMAN
NC score	0.027011 (rank : 1541)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	457	Target Neighborhood Hits	428	Shared Neighborhood Hits	37
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PKN2_MOUSE
NC score	0.026167 (rank : 1542)	θ value	2.36792 (rank : 372)
Query Neighborhood Hits	457	Target Neighborhood Hits	899	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

NKTR_MOUSE
NC score	0.025086 (rank : 1543)	θ value	2.36792 (rank : 371)
Query Neighborhood Hits	457	Target Neighborhood Hits	417	Shared Neighborhood Hits	47
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

41_MOUSE
NC score	0.023770 (rank : 1544)	θ value	5.27518 (rank : 399)
Query Neighborhood Hits	457	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

ICAL_MOUSE
NC score	0.023275 (rank : 1545)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	457	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

41_HUMAN
NC score	0.023241 (rank : 1546)	θ value	4.03905 (rank : 388)
Query Neighborhood Hits	457	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

TEX2_MOUSE
NC score	0.022442 (rank : 1547)	θ value	1.81305 (rank : 359)
Query Neighborhood Hits	457	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

CHD9_HUMAN
NC score	0.021470 (rank : 1548)	θ value	1.81305 (rank : 342)
Query Neighborhood Hits	457	Target Neighborhood Hits	343	Shared Neighborhood Hits	56
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD1_HUMAN
NC score	0.018645 (rank : 1549)	θ value	2.36792 (rank : 362)
Query Neighborhood Hits	457	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CBP_MOUSE
NC score	0.018375 (rank : 1550)	θ value	2.36792 (rank : 361)
Query Neighborhood Hits	457	Target Neighborhood Hits	1051	Shared Neighborhood Hits	46
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EP400_HUMAN
NC score	0.017626 (rank : 1551)	θ value	2.36792 (rank : 364)
Query Neighborhood Hits	457	Target Neighborhood Hits	556	Shared Neighborhood Hits	36
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

TRI22_HUMAN
NC score	0.016519 (rank : 1552)	θ value	1.06291 (rank : 328)
Query Neighborhood Hits	457	Target Neighborhood Hits	396	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

DNAI2_HUMAN
NC score	0.013725 (rank : 1553)	θ value	6.88961 (rank : 426)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

CM003_HUMAN
NC score	0.010733 (rank : 1554)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	457	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX90, Q5VZV5, Q86WR2, Q8NBG1, Q96D22	Gene names	C13orf3, RAMA1
Domain Architecture	No domain graphic available
Description	Protein C13orf3.

ZN198_HUMAN
NC score	0.008581 (rank : 1555)	θ value	6.88961 (rank : 437)
Query Neighborhood Hits	457	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

B4GN4_MOUSE
NC score	0.007996 (rank : 1556)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	457	Target Neighborhood Hits	129	Shared Neighborhood Hits	11
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

TMC2_HUMAN
NC score	0.007482 (rank : 1557)	θ value	8.99809 (rank : 456)
Query Neighborhood Hits	457	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

JHD3D_MOUSE
NC score	0.006017 (rank : 1558)	θ value	4.03905 (rank : 395)
Query Neighborhood Hits	457	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

CPXM1_MOUSE
NC score	0.005283 (rank : 1559)	θ value	2.36792 (rank : 363)
Query Neighborhood Hits	457	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

FKBP5_MOUSE
NC score	0.003892 (rank : 1560)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	457	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

THIM_MOUSE
NC score	0.003616 (rank : 1561)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	457	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWT1, Q8JZR8	Gene names	Acaa2
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltransferase) (Mitochondrial 3-oxoacyl- CoA thiolase).

ANXA6_MOUSE
NC score	0.002657 (rank : 1562)	θ value	6.88961 (rank : 419)
Query Neighborhood Hits	457	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P14824	Gene names	Anxa6, Anx6
Domain Architecture
Description	Annexin A6 (Annexin VI) (Lipocortin VI) (P68) (P70) (Protein III) (Chromobindin-20) (67 kDa calelectrin) (Calphobindin-II) (CPB-II).

DDX24_HUMAN
NC score	0.002090 (rank : 1563)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	457	Target Neighborhood Hits	190	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

CAD18_HUMAN
NC score	-0.002801 (rank : 1564)	θ value	4.03905 (rank : 391)
Query Neighborhood Hits	457	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q13634	Gene names	CDH18, CDH14
Domain Architecture
Description	Cadherin-18 precursor (Cadherin-14).